Greg A. Somerville - Publications

Affiliations: 
Integrative Biomedical Sciences The University of Nebraska - Lincoln, Lincoln, NE 
Area:
Microbiology Biology, Biochemistry

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Kebriaei R, Bayer AS, Lapitan CK, Rybak MJ, Somerville GA, Mishra NN. Activity of the Lactate Dehydrogenase Inhibitor Oxamic Acid against the Fermentative Bacterium : Bactericidal Effects and Prevention of Daptomycin Resistance In Vitro and in an Ex Vivo Model. Antibiotics (Basel, Switzerland). 11. PMID 36290066 DOI: 10.3390/antibiotics11101409  0.36
2022 Somerville GA, Parrett AA, Reed JM, Gardner SG, Morton M, Powers R. Human Serum Alters the Metabolism and Antibiotic Susceptibility of . Journal of Proteome Research. PMID 35537087 DOI: 10.1021/acs.jproteome.2c00073  0.401
2021 Pätzold L, Brausch AC, Bielefeld EL, Zimmer L, Somerville GA, Bischoff M, Gaupp R. Impact of the Histidine-Containing Phosphocarrier Protein HPr on Carbon Metabolism and Virulence in . Microorganisms. 9. PMID 33668335 DOI: 10.3390/microorganisms9030466  0.41
2020 Parrett A, Reed JM, Gardner SG, Mishra NN, Bayer AS, Powers R, Somerville GA. Metabolic changes associated with adaptive resistance to daptomycin in Streptococcus mitis-oralis. Bmc Microbiology. 20: 162. PMID 32539684 DOI: 10.1186/S12866-020-01849-W  0.459
2019 Gunaratnam G, Tuchscherr L, Elhawy MI, Bertram R, Eisenbeis J, Spengler C, Tschernig T, Löffler B, Somerville GA, Jacobs K, Herrmann M, Bischoff M. ClpC affects the intracellular survival capacity of Staphylococcus aureus in non-professional phagocytic cells. Scientific Reports. 9: 16267. PMID 31700127 DOI: 10.1038/S41598-019-52731-3  0.457
2019 Reed JM, Gardner SG, Mishra NN, Bayer AS, Somerville GA. Metabolic interventions for the prevention and treatment of daptomycin non-susceptibility in Staphylococcus aureus. The Journal of Antimicrobial Chemotherapy. PMID 31074482 DOI: 10.1093/Jac/Dkz194  0.435
2019 Somerville G, Powers R, Rose, W, Miro J, Bayer A, Mishra N. 614. Metabolic Interventions for the Resensitization of Daptomycin-Resistant (DAP-R) Streptococcus mitis-oralis Strains to DAP In vitro and Ex Vivo in a Simulated Model of Experimental Endocarditis (IE) Open Forum Infectious Diseases. 6: S286-S286. DOI: 10.1093/Ofid/Ofz360.2511  0.388
2018 Reed JM, Olson S, Brees DF, Griffin CE, Grove RA, Davis PJ, Kachman SD, Adamec J, Somerville GA. Coordinated regulation of transcription by CcpA and the Staphylococcus aureus two-component system HptRS. Plos One. 13: e0207161. PMID 30540769 DOI: 10.1371/Journal.Pone.0207161  0.478
2017 Gardner SG, Marshall DD, Daum RS, Powers R, Somerville GA. Metabolic Mitigation of Staphylococcus aureus Vancomycin Intermediate-Level Susceptibility. Antimicrobial Agents and Chemotherapy. PMID 29109158 DOI: 10.1128/Aac.01608-17  0.497
2017 Stevens E, Laabei M, Gardner S, Somerville GA, Massey RC. Cytolytic toxin production by Staphylococcus aureus is dependent upon the activity of the protoheme IX farnesyltransferase. Scientific Reports. 7: 13744. PMID 29062030 DOI: 10.1038/S41598-017-14110-8  0.463
2017 Bischoff M, Wonnenberg B, Nippe N, Nyffenegger-Jann NJ, Voss M, Beisswenger C, Sunderkötter C, Molle V, Dinh QT, Lammert F, Bals R, Herrmann M, Somerville GA, Tschernig T, Gaupp R. CcpA Affects Infectivity of Staphylococcus aureus in a Hyperglycemic Environment. Frontiers in Cellular and Infection Microbiology. 7: 172. PMID 28536677 DOI: 10.3389/Fcimb.2017.00172  0.394
2016 Gradnigo JS, Somerville GA, Huether MJ, Kemmy RJ, Johnson CM, Oliver MG, Moriyama EN. Genome Sequence of Streptomyces aureofaciens ATCC Strain 10762. Genome Announcements. 4. PMID 27340076 DOI: 10.1128/Genomea.00615-16  0.321
2016 Gaupp R, Wirf J, Wonnenberg B, Biegel T, Eisenbeis J, Graham J, Herrmann M, Lee CY, Beisswenger C, Wolz C, Tschernig T, Bischoff M, Somerville GA. RpiRc is a pleiotropic effector of virulence determinant synthesis and attenuates pathogenicity in Staphylococcus aureus. Infection and Immunity. PMID 27113358 DOI: 10.1128/Iai.00285-16  0.53
2015 Richardson AR, Somerville GA, Sonenshein AL. Regulating the Intersection of Metabolism and Pathogenesis in Gram-positive Bacteria. Microbiology Spectrum. 3. PMID 26185086 DOI: 10.1128/Microbiolspec.Mbp-0004-2014  0.492
2015 Gaupp R, Lei S, Reed JM, Peisker H, Boyle-Vavra S, Bayer AS, Bischoff M, Herrmann M, Daum RS, Powers R, Somerville GA. Staphylococcus aureus Metabolic Adaptations during the Transition from a Daptomycin Susceptibility Phenotype to a Daptomycin Nonsusceptibility Phenotype. Antimicrobial Agents and Chemotherapy. 59: 4226-38. PMID 25963986 DOI: 10.1128/Aac.00160-15  0.521
2014 Hartmann T, Baronian G, Nippe N, Voss M, Schulthess B, Wolz C, Eisenbeis J, Schmidt-Hohagen K, Gaupp R, Sunderkötter C, Beisswenger C, Bals R, Somerville GA, Herrmann M, Molle V, et al. The catabolite control protein E (CcpE) affects virulence determinant production and pathogenesis of Staphylococcus aureus. The Journal of Biological Chemistry. 289: 29701-11. PMID 25193664 DOI: 10.1074/Jbc.M114.584979  0.501
2014 Ledala N, Zhang B, Seravalli J, Powers R, Somerville GA. Influence of iron and aeration on Staphylococcus aureus growth, metabolism, and transcription. Journal of Bacteriology. 196: 2178-89. PMID 24706736 DOI: 10.1128/Jb.01475-14  0.391
2014 Stark JL, Copeland JC, Eletsky A, Somerville GA, Szyperski T, Powers R. Identification of low-molecular-weight compounds inhibiting growth of corynebacteria: potential lead compounds for antibiotics. Chemmedchem. 9: 282-5. PMID 24403054 DOI: 10.1002/Cmdc.201300386  0.307
2014 Somerville GA, Powers R. Growth and preparation of Staphylococcus epidermidis for NMR metabolomic analysis. Methods in Molecular Biology (Clifton, N.J.). 1106: 71-91. PMID 24222456 DOI: 10.1007/978-1-62703-736-5_6  0.394
2013 Hartmann T, Zhang B, Baronian G, Schulthess B, Homerova D, Grubmüller S, Kutzner E, Gaupp R, Bertram R, Powers R, Eisenreich W, Kormanec J, Herrmann M, Molle V, Somerville GA, et al. Catabolite control protein E (CcpE) is a LysR-type transcriptional regulator of tricarboxylic acid cycle activity in Staphylococcus aureus. The Journal of Biological Chemistry. 288: 36116-28. PMID 24194525 DOI: 10.1074/Jbc.M113.516302  0.517
2013 Thomas VC, Chittezham Thomas V, Kinkead LC, Janssen A, Schaeffer CR, Woods KM, Lindgren JK, Peaster JM, Chaudhari SS, Sadykov M, Jones J, AbdelGhani SM, Zimmerman MC, Bayles KW, Somerville GA, et al. A dysfunctional tricarboxylic acid cycle enhances fitness of Staphylococcus epidermidis during β-lactam stress. Mbio. 4. PMID 23963176 DOI: 10.1128/Mbio.00437-13  0.436
2013 Somerville GA, Proctor RA. Cultivation conditions and the diffusion of oxygen into culture media: the rationale for the flask-to-medium ratio in microbiology. Bmc Microbiology. 13: 9. PMID 23324109 DOI: 10.1186/1471-2180-13-9  0.319
2011 Sadykov MR, Hartmann T, Mattes TA, Hiatt M, Jann NJ, Zhu Y, Ledala N, Landmann R, Herrmann M, Rohde H, Bischoff M, Somerville GA. CcpA coordinates central metabolism and biofilm formation in Staphylococcus epidermidis. Microbiology (Reading, England). 157: 3458-68. PMID 21964732 DOI: 10.1099/Mic.0.051243-0  0.658
2011 Zhu Y, Nandakumar R, Sadykov MR, Madayiputhiya N, Luong TT, Gaupp R, Lee CY, Somerville GA. RpiR homologues may link Staphylococcus aureus RNAIII synthesis and pentose phosphate pathway regulation. Journal of Bacteriology. 193: 6187-96. PMID 21926234 DOI: 10.1128/Jb.05930-11  0.638
2011 Zhang B, Halouska S, Schiaffo CE, Sadykov MR, Somerville GA, Powers R. NMR analysis of a stress response metabolic signaling network. Journal of Proteome Research. 10: 3743-54. PMID 21692534 DOI: 10.1021/Pr200360W  0.466
2011 Massilamany C, Gangaplara A, Gardner DJ, Musser JM, Steffen D, Somerville GA, Reddy J. TCA cycle inactivation in Staphylococcus aureus alters nitric oxide production in RAW 264.7 cells. Molecular and Cellular Biochemistry. 355: 75-82. PMID 21519920 DOI: 10.1007/S11010-011-0840-3  0.466
2010 Sadykov MR, Zhang B, Halouska S, Nelson JL, Kreimer LW, Zhu Y, Powers R, Somerville GA. Using NMR metabolomics to investigate tricarboxylic acid cycle-dependent signal transduction in Staphylococcus epidermidis. The Journal of Biological Chemistry. 285: 36616-24. PMID 20861019 DOI: 10.1074/Jbc.M110.152843  0.604
2010 Majerczyk CD, Dunman PM, Luong TT, Lee CY, Sadykov MR, Somerville GA, Bodi K, Sonenshein AL. Direct targets of CodY in Staphylococcus aureus. Journal of Bacteriology. 192: 2861-77. PMID 20363936 DOI: 10.1128/Jb.00220-10  0.439
2010 Sadykov MR, Mattes TA, Luong TT, Zhu Y, Day SR, Sifri CD, Lee CY, Somerville GA. Tricarboxylic acid cycle-dependent synthesis of Staphylococcus aureus Type 5 and 8 capsular polysaccharides. Journal of Bacteriology. 192: 1459-62. PMID 20061474 DOI: 10.1128/Jb.01377-09  0.597
2009 Zhu Y, Xiong YQ, Sadykov MR, Fey PD, Lei MG, Lee CY, Bayer AS, Somerville GA. Tricarboxylic acid cycle-dependent attenuation of Staphylococcus aureus in vivo virulence by selective inhibition of amino acid transport. Infection and Immunity. 77: 4256-64. PMID 19667045 DOI: 10.1128/Iai.00195-09  0.646
2009 Somerville GA, Proctor RA. At the crossroads of bacterial metabolism and virulence factor synthesis in Staphylococci. Microbiology and Molecular Biology Reviews : Mmbr. 73: 233-48. PMID 19487727 DOI: 10.1128/Mmbr.00005-09  0.486
2009 Chatterjee I, Schmitt S, Batzilla CF, Engelmann S, Keller A, Ring MW, Kautenburger R, Ziebuhr W, Hecker M, Preissner KT, Bischoff M, Proctor RA, Beck HP, Lenhof HP, Somerville GA, et al. Staphylococcus aureus ClpC ATPase is a late growth phase effector of metabolism and persistence. Proteomics. 9: 1152-76. PMID 19253280 DOI: 10.1002/Pmic.200800586  0.46
2008 Sadykov MR, Olson ME, Halouska S, Zhu Y, Fey PD, Powers R, Somerville GA. Tricarboxylic acid cycle-dependent regulation of Staphylococcus epidermidis polysaccharide intercellular adhesin synthesis. Journal of Bacteriology. 190: 7621-32. PMID 18820013 DOI: 10.1128/Jb.00806-08  0.668
2008 Majerczyk CD, Sadykov MR, Luong TT, Lee C, Somerville GA, Sonenshein AL. Staphylococcus aureus CodY negatively regulates virulence gene expression Journal of Bacteriology. 190: 2257-2265. PMID 18156263 DOI: 10.1128/Jb.01545-07  0.497
2008 Handke LD, Rogers KL, Olson ME, Somerville GA, Jerrells TJ, Rupp ME, Dunman PM, Fey PD. Staphylococcus epidermidis saeR is an effector of anaerobic growth and a mediator of acute inflammation. Infection and Immunity. 76: 141-52. PMID 17954724 DOI: 10.1128/Iai.00556-07  0.49
2007 Zhu Y, Weiss EC, Otto M, Fey PD, Smeltzer MS, Somerville GA. Staphylococcus aureus biofilm metabolism and the influence of arginine on polysaccharide intercellular adhesin synthesis, biofilm formation, and pathogenesis. Infection and Immunity. 75: 4219-26. PMID 17576756 DOI: 10.1128/Iai.00509-07  0.635
2007 Nelson JL, Rice KC, Slater SR, Fox PM, Archer GL, Bayles KW, Fey PD, Kreiswirth BN, Somerville GA. Vancomycin-intermediate Staphylococcus aureus strains have impaired acetate catabolism: implications for polysaccharide intercellular adhesin synthesis and autolysis. Antimicrobial Agents and Chemotherapy. 51: 616-22. PMID 17130298 DOI: 10.1128/Aac.01057-06  0.469
2006 Chatterjee I, Somerville GA, Heilmann C, Sahl HG, Maurer HH, Herrmann M. Very low ethanol concentrations affect the viability and growth recovery in post-stationary-phase Staphylococcus aureus populations. Applied and Environmental Microbiology. 72: 2627-36. PMID 16597967 DOI: 10.1128/Aem.72.4.2627-2636.2006  0.355
2005 Chatterjee I, Becker P, Grundmeier M, Bischoff M, Somerville GA, Peters G, Sinha B, Harraghy N, Proctor RA, Herrmann M. Staphylococcus aureus ClpC is required for stress resistance, aconitase activity, growth recovery, and death. Journal of Bacteriology. 187: 4488-96. PMID 15968059 DOI: 10.1128/Jb.187.13.4488-4496.2005  0.489
2005 Vuong C, Kidder JB, Jacobson ER, Otto M, Proctor RA, Somerville GA. Staphylococcus epidermidis polysaccharide intercellular adhesin production significantly increases during tricarboxylic acid cycle stress. Journal of Bacteriology. 187: 2967-73. PMID 15838022 DOI: 10.1128/Jb.187.9.2967-2973.2005  0.444
2004 Banks DJ, Porcella SF, Barbian KD, Beres SB, Philips LE, Voyich JM, DeLeo FR, Martin JM, Somerville GA, Musser JM. Progress toward characterization of the group A Streptococcus metagenome: complete genome sequence of a macrolide-resistant serotype M6 strain. The Journal of Infectious Diseases. 190: 727-38. PMID 15272401 DOI: 10.1086/422697  0.334
2004 Chenoweth MR, Somerville GA, Krause DC, O'Reilly KL, Gherardini FC. Growth characteristics of Bartonella henselae in a novel liquid medium: primary isolation, growth-phase-dependent phage induction, and metabolic studies. Applied and Environmental Microbiology. 70: 656-63. PMID 14766538 DOI: 10.1128/Aem.70.2.656-663.2004  0.414
2003 Somerville GA, Cockayne A, Dürr M, Peschel A, Otto M, Musser JM. Synthesis and deformylation of Staphylococcus aureus delta-toxin are linked to tricarboxylic acid cycle activity. Journal of Bacteriology. 185: 6686-94. PMID 14594843 DOI: 10.1128/Jb.185.22.6686-6694.2003  0.448
2003 Chaussee MS, Somerville GA, Reitzer L, Musser JM. Rgg coordinates virulence factor synthesis and metabolism in Streptococcus pyogenes. Journal of Bacteriology. 185: 6016-24. PMID 14526012 DOI: 10.1128/Jb.185.20.6016-6024.2003  0.526
2003 Vuong C, Gerke C, Somerville GA, Fischer ER, Otto M. Quorum-sensing control of biofilm factors in Staphylococcus epidermidis. The Journal of Infectious Diseases. 188: 706-18. PMID 12934187 DOI: 10.1086/377239  0.469
2003 Somerville GA, Saïd-Salim B, Wickman JM, Raffel SJ, Kreiswirth BN, Musser JM. Correlation of acetate catabolism and growth yield in Staphylococcus aureus: implications for host-pathogen interactions. Infection and Immunity. 71: 4724-32. PMID 12874354 DOI: 10.1128/Iai.71.8.4724-4732.2003  0.489
2003 Schwan TG, Battisti JM, Porcella SF, Raffel SJ, Schrumpf ME, Fischer ER, Carroll JA, Stewart PE, Rosa P, Somerville GA. Glycerol-3-phosphate acquisition in spirochetes: distribution and biological activity of glycerophosphodiester phosphodiesterase (GlpQ) among Borrelia species. Journal of Bacteriology. 185: 1346-56. PMID 12562805 DOI: 10.1128/Jb.185.4.1346-1356.2003  0.316
2003 Kobayashi SD, Voyich JM, Somerville GA, Braughton KR, Malech HL, Musser JM, DeLeo FR. An apoptosis-differentiation program in human polymorphonuclear leukocytes facilitates resolution of inflammation. Journal of Leukocyte Biology. 73: 315-22. PMID 12554809 DOI: 10.1189/Jlb.1002481  0.381
2002 Somerville GA, Chaussee MS, Morgan CI, Fitzgerald JR, Dorward DW, Reitzer LJ, Musser JM. Staphylococcus aureus aconitase inactivation unexpectedly inhibits post-exponential-phase growth and enhances stationary-phase survival. Infection and Immunity. 70: 6373-82. PMID 12379717 DOI: 10.1128/Iai.70.11.6373-6382.2002  0.449
2002 Somerville GA, Beres SB, Fitzgerald JR, DeLeo FR, Cole RL, Hoff JS, Musser JM. In vitro serial passage of Staphylococcus aureus: changes in physiology, virulence factor production, and agr nucleotide sequence. Journal of Bacteriology. 184: 1430-7. PMID 11844774 DOI: 10.1128/Jb.184.5.1430-1437.2002  0.39
2001 Smoot LM, Smoot JC, Graham MR, Somerville GA, Sturdevant DE, Migliaccio CA, Sylva GL, Musser JM. Global differential gene expression in response to growth temperature alteration in group A Streptococcus. Proceedings of the National Academy of Sciences of the United States of America. 98: 10416-21. PMID 11517341 DOI: 10.1073/Pnas.191267598  0.377
1999 Somerville G, Mikoryak CA, Reitzer L. Physiological Characterization of Pseudomonas aeruginosa during Exotoxin A Synthesis: Glutamate, Iron Limitation, and Aconitase Activity Journal of Bacteriology. 181: 1072-1078. PMID 9973331 DOI: 10.1128/Jb.181.4.1072-1078.1999  0.408
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