Trudy Mackay - Publications

Affiliations: 
North Carolina State University, Raleigh, NC 
Area:
Genetics, Neuroscience Biology

164 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Rand MD, Tennessen JM, Mackay TFC, Anholt RRH. Perspectives on the Drosophila melanogaster Model for Advances in Toxicological Science. Current Protocols. 3: e870. PMID 37639638 DOI: 10.1002/cpz1.870  0.322
2023 Lyman RF, Lyman RA, Yamamoto A, Huang W, Harbison ST, Zhou S, Anholt RRH, Mackay TFC. Natural genetic variation in a dopamine receptor is associated with variation in female fertility in . Proceedings. Biological Sciences. 290: 20230375. PMID 37040806 DOI: 10.1098/rspb.2023.0375  0.812
2023 MacPherson RA, Shankar V, Anholt RRH, Mackay TFC. Genetic and Genomic Analyses of Drosophila melanogaster Models of Chromatin Modification Disorders. Genetics. PMID 37036413 DOI: 10.1093/genetics/iyad061  0.35
2023 MacPherson RA, Shankar V, Anholt RRH, Mackay TFC. Genetic and Genomic Analyses of Models of Chromatin Modification Disorders. Biorxiv : the Preprint Server For Biology. PMID 37034595 DOI: 10.1101/2023.03.30.534923  0.339
2023 Anholt RRH, Mackay TFC. The genetic architecture of behavioral canalization. Trends in Genetics : Tig. PMID 36878820 DOI: 10.1016/j.tig.2023.02.007  0.406
2022 Mackay TFC, Anholt RRH. Gregor Mendel's legacy in quantitative genetics. Plos Biology. 20: e3001692. PMID 35852997 DOI: 10.1371/journal.pbio.3001692  0.327
2021 Özsoy ED, Yılmaz M, Patlar B, Emecen G, Durmaz E, Magwire MM, Zhou S, Huang W, Anholt RRH, Mackay TFC. Epistasis for head morphology in Drosophila melanogaster. G3 (Bethesda, Md.). 11. PMID 34568933 DOI: 10.1093/g3journal/jkab285  0.829
2021 Baker BM, Carbone MA, Huang W, Anholt RRH, Mackay TFC. Genetic basis of variation in cocaine and methamphetamine consumption in outbred populations of . Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34074789 DOI: 10.1073/pnas.2104131118  0.447
2021 Tallo CA, Duncan LH, Yamamoto AH, Slaydon JD, Arya GH, Turlapati L, Mackay TFC, Carbone MA. Heat shock proteins and small nucleolar RNAs are dysregulated in a Drosophila model for feline hypertrophic cardiomyopathy. G3 (Bethesda, Md.). 11. PMID 33561224 DOI: 10.1093/g3journal/jkaa014  0.325
2020 Huang W, Carbone MA, Lyman RF, Anholt RRH, Mackay TFC. Genotype by environment interaction for gene expression in Drosophila melanogaster. Nature Communications. 11: 5451. PMID 33116142 DOI: 10.1038/s41467-020-19131-y  0.435
2020 Morgante F, Huang W, Sørensen P, Maltecca C, Mackay TFC. Leveraging Multiple Layers of Data To Predict Complex Traits. G3 (Bethesda, Md.). PMID 33106232 DOI: 10.1534/g3.120.401847  0.361
2020 Yanagawa A, Huang W, Yamamoto A, Wada-Katsumata A, Schal C, Mackay TFC. Genetic Basis of Natural Variation in Spontaneous Grooming in . G3 (Bethesda, Md.). PMID 32727922 DOI: 10.1534/G3.120.401360  0.452
2020 Everett LJ, Huang W, Zhou S, Carbone MA, Lyman RF, Arya GH, Geisz MS, Ma J, Morgante F, St Armour G, Turlapati L, Anholt RRH, Mackay T. Gene expression networks in the Genetic Reference Panel. Genome Research. PMID 32144088 DOI: 10.1101/Gr.257592.119  0.64
2020 Huang W, Campbell T, Carbone MA, Jones WE, Unselt D, Anholt RRH, Mackay TFC. Context-dependent genetic architecture of Drosophila life span. Plos Biology. 18: e3000645. PMID 32134916 DOI: 10.1371/journal.pbio.3000645  0.412
2020 Parker GA, Kohn N, Spirina A, McMillen A, Huang W, Mackay TFC. Genetic Basis of Increased Lifespan and Postponed Senescence in . G3 (Bethesda, Md.). PMID 31969430 DOI: 10.1534/g3.120.401041  0.465
2019 Zhou S, Morgante F, Geisz M, Ma J, Anholt R, Mackay T. Systems Genetics of the Metabolome. Genome Research. PMID 31694867 DOI: 10.1101/Gr.243030.118  0.637
2019 Highfill CA, Baker BM, Stevens SD, Anholt RRH, Mackay TFC. Genetics of cocaine and methamphetamine consumption and preference in Drosophila melanogaster. Plos Genetics. 15: e1007834. PMID 31107875 DOI: 10.1371/journal.pgen.1007834  0.344
2018 Harbison ST, Kumar S, Huang W, McCoy LJ, Smith KR, Mackay TFC. Genome-Wide Association Study of Circadian Behavior in Drosophila melanogaster. Behavior Genetics. PMID 30341464 DOI: 10.1007/S10519-018-9932-0  0.786
2018 Morozova TV, Hussain Y, McCoy LJ, Zhirnov EV, Davis MR, Pray VA, Lyman RA, Duncan LH, McMillen A, Jones A, Mackay TFC, Anholt RRH. A Centered Genetic Network Contributes to Alcohol-Induced Variation in Development. G3 (Bethesda, Md.). PMID 29871898 DOI: 10.1534/g3.118.200260  0.351
2018 Rohde PD, Østergaard S, Kristensen TN, Sørensen P, Loeschcke V, Mackay TFC, Sarup P. Functional Validation of Candidate Genes Detected by Genomic Feature Models. G3 (Bethesda, Md.). PMID 29519937 DOI: 10.1534/G3.118.200082  0.404
2018 Meurs KM, Friedenberg SG, Williams B, Keene BW, Atkins CE, Adin D, Aona B, DeFrancesco T, Tou S, Mackay T. Evaluation of genes associated with human myxomatous mitral valve disease in dogs with familial myxomatous mitral valve degeneration. Veterinary Journal (London, England : 1997). 232: 16-19. PMID 29428085 DOI: 10.1016/J.Tvjl.2017.12.002  0.404
2018 Morgante F, Huang W, Maltecca C, Mackay TFC. Effect of genetic architecture on the prediction accuracy of quantitative traits in samples of unrelated individuals. Heredity. PMID 29426878 DOI: 10.1038/s41437-017-0043-0  0.367
2017 Anholt RRH, Mackay TFC. The road less traveled: from genotype to phenotype in flies and humans. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 29058036 DOI: 10.1007/s00335-017-9722-7  0.48
2017 Mackay TFC, Huang W. Charting the genotype-phenotype map: lessons from the Drosophila melanogaster Genetic Reference Panel. Wiley Interdisciplinary Reviews. Developmental Biology. PMID 28834395 DOI: 10.1002/wdev.289  0.511
2017 Zhou S, Luoma SE, St Armour GE, Thakkar E, Mackay TFC, Anholt RRH. A drosophila model for toxicogenomics: Genetic variation in susceptibility to heavy metal exposure. Plos Genetics. 13: e1006907. PMID 28732062 DOI: 10.1371/Journal.Pgen.1006907  0.591
2017 Garcia JF, Carbone MA, Mackay TFC, Anholt RRH. Regulation of Drosophila Lifespan by bellwether Promoter Alleles. Scientific Reports. 7: 4109. PMID 28646164 DOI: 10.1038/s41598-017-04530-x  0.381
2017 Fochler S, Morozova TV, Davis MR, Gearhart AW, Huang W, Mackay TFC, Anholt RRH. Genetics of Alcohol Consumption in Drosophila melanogaster. Genes, Brain, and Behavior. PMID 28627812 DOI: 10.1111/gbb.12399  0.463
2017 Rohde PD, Gaertner B, Wards K, Sørensen P, Mackay TFC. Genomic Analysis of Genotype by Social Environment Interaction for Drosophila Aggressive Behavior. Genetics. PMID 28550016 DOI: 10.1534/Genetics.117.200642  0.37
2016 Huang W, Mackay TF. The Genetic Architecture of Quantitative Traits Cannot Be Inferred from Variance Component Analysis. Plos Genetics. 12: e1006421. PMID 27812106 DOI: 10.1371/journal.pgen.1006421  0.462
2016 Carbone MA, Yamamoto A, Huang W, Lyman RA, Meadors TB, Yamamoto R, Anholt RR, Mackay TF. Genetic architecture of natural variation in visual senescence in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 113: E6620-E6629. PMID 27791033 DOI: 10.1073/pnas.1613833113  0.431
2016 Huang W, Lyman RF, Lyman RA, Carbone MA, Harbison ST, Magwire MM, Mackay TF. Correction: Spontaneous mutations and the origin and maintenance of quantitative genetic variation. Elife. 5. PMID 27759564 DOI: 10.7554/Elife.22300  0.818
2016 Garlapow ME, Everett LJ, Zhou S, Gearhart AW, Fay KA, Huang W, Morozova TV, Arya GH, Turlapati L, St Armour G, Hussain YN, McAdams SE, Fochler S, Mackay TF. Genetic and Genomic Response to Selection for Food Consumption in Drosophila melanogaster. Behavior Genetics. PMID 27704301 DOI: 10.1007/S10519-016-9819-X  0.503
2016 Friedenberg SG, Meurs KM, Mackay TF. Evaluation of artificial selection in Standard Poodles using whole-genome sequencing. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 27510710 DOI: 10.1007/s00335-016-9660-9  0.359
2016 Edwards SM, Sørensen IF, Sarup P, Mackay TF, Sørensen P. Genomic Prediction for Quantitative Traits Is Improved by Mapping Variants to Gene Ontology Categories in Drosophila melanogaster. Genetics. PMID 27235308 DOI: 10.1534/genetics.116.187161  0.421
2016 Huang W, Lyman RF, Lyman RA, Carbone MA, Harbison ST, Magwire MM, Mackay TF. Spontaneous mutations and the origin and maintenance of quantitative genetic variation. Elife. 5. PMID 27213517 DOI: 10.7554/Elife.14625  0.823
2016 Hunter CM, Huang W, Mackay TF, Singh ND. The Genetic Architecture of Natural Variation in Recombination Rate in Drosophila melanogaster. Plos Genetics. 12: e1005951. PMID 27035832 DOI: 10.1371/Journal.Pgen.1005951  0.432
2016 Riedl CA, Oster S, Busto M, Mackay TF, Sokolowski MB. Natural variability in Drosophila larval and pupal NaCl tolerance. Journal of Insect Physiology. 88: 15-23. PMID 26874056 DOI: 10.1016/j.jinsphys.2016.02.007  0.346
2016 Zhou S, Morozova TV, Hussain YN, Luoma SE, McCoy L, Yamamoto A, Mackay TF, Anholt RR. The Genetic Basis for Variation in Sensitivity to Lead Toxicity in Drosophila melanogaster. Environmental Health Perspectives. PMID 26859824 DOI: 10.1289/Ehp.1510513  0.514
2016 Vonesch SC, Lamparter D, Mackay TF, Bergmann S, Hafen E. Genome-Wide Analysis Reveals Novel Regulators of Growth in Drosophila melanogaster. Plos Genetics. 12: e1005616. PMID 26751788 DOI: 10.1371/Journal.Pgen.1005616  0.475
2015 He X, Zhou S, St Armour GE, Mackay TF, Anholt RR. Epistatic Partners of Neurogenic Genes Modulate Drosophila Olfactory Behavior. Genes, Brain, and Behavior. PMID 26678546 DOI: 10.1111/gbb.12279  0.665
2015 Zwarts L, Vanden Broeck L, Cappuyns E, Ayroles JF, Magwire MM, Vulsteke V, Clements J, Mackay TF, Callaerts P. The genetic basis of natural variation in mushroom body size in Drosophila melanogaster. Nature Communications. 6: 10115. PMID 26656654 DOI: 10.1038/Ncomms10115  0.771
2015 Dembeck LM, Böröczky K, Huang W, Schal C, Anholt RR, Mackay TF. Genetic architecture of natural variation in cuticularhydrocarbon composition in Drosophila melanogaster. Elife. 4. PMID 26568309 DOI: 10.7554/Elife.09861  0.411
2015 Dembeck LM, Huang W, Carbone MA, Mackay TF. Genetic Basis of Natural Variation in Body Pigmentation in Drosophila melanogaster. Fly. 0. PMID 26554300 DOI: 10.1080/19336934.2015.1102807  0.492
2015 Morozova TV, Huang W, Pray VA, Whitham T, Anholt RR, Mackay TF. Polymorphisms in early neurodevelopmental genes affect natural variation in alcohol sensitivity in adult drosophila. Bmc Genomics. 16: 865. PMID 26503115 DOI: 10.1186/s12864-015-2064-5  0.34
2015 Huang W, Carbone MA, Magwire MM, Peiffer JA, Lyman RF, Stone EA, Anholt RR, Mackay TF. Genetic basis of transcriptome diversity in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. PMID 26483487 DOI: 10.1073/Pnas.1519159112  0.802
2015 Carnes MU, Campbell T, Huang W, Butler DG, Carbone MA, Duncan LH, Harbajan SV, King EM, Peterson KR, Weitzel A, Zhou S, Mackay TF. The Genomic Basis of Postponed Senescence in Drosophila melanogaster. Plos One. 10: e0138569. PMID 26378456 DOI: 10.1371/Journal.Pone.0138569  0.6
2015 Sørensen P, de Los Campos G, Morgante F, Mackay TF, Sorensen D. Genetic Control of Environmental Variation of Two Quantitative Traits of Drosophila melanogaster Revealed by Whole-Genome Sequencing. Genetics. 201: 487-97. PMID 26269504 DOI: 10.1534/genetics.115.180273  0.424
2015 Shorter JR, Geisz M, Özsoy E, Magwire MM, Carbone MA, Mackay TF. The Effects of Royal Jelly on Fitness Traits and Gene Expression in Drosophila melanogaster. Plos One. 10: e0134612. PMID 26226016 DOI: 10.1371/Journal.Pone.0134612  0.714
2015 Anholt RR, Mackay TF. Dissecting the Genetic Architecture of Behavior in Drosophila melanogaster. Current Opinion in Behavioral Sciences. 2: 1-7. PMID 26203460 DOI: 10.1016/j.cobeha.2014.06.001  0.471
2015 Ober U, Huang W, Magwire M, Schlather M, Simianer H, Mackay TF. Correction: Accounting for Genetic Architecture Improves Sequence Based Genomic Prediction for a Drosophila Fitness Trait. Plos One. 10: e0132980. PMID 26167869 DOI: 10.1371/journal.pone.0132980  0.736
2015 Shorter J, Couch C, Huang W, Carbone MA, Peiffer J, Anholt RR, Mackay TF. Genetic architecture of natural variation in Drosophila melanogaster aggressive behavior. Proceedings of the National Academy of Sciences of the United States of America. PMID 26100892 DOI: 10.1073/Pnas.1510104112  0.528
2015 Ober U, Huang W, Magwire M, Schlather M, Simianer H, Mackay TF. Accounting for genetic architecture improves sequence based genomic prediction for a Drosophila fitness trait. Plos One. 10: e0126880. PMID 25950439 DOI: 10.1371/Journal.Pone.0126880  0.765
2015 Morgante F, Sørensen P, Sorensen DA, Maltecca C, Mackay TF. Genetic Architecture of Micro-Environmental Plasticity in Drosophila melanogaster. Scientific Reports. 5: 9785. PMID 25943032 DOI: 10.1038/srep09785  0.455
2015 Dembeck LM, Huang W, Magwire MM, Lawrence F, Lyman RF, Mackay TF. Genetic Architecture of Abdominal Pigmentation in Drosophila melanogaster. Plos Genetics. 11: e1005163. PMID 25933381 DOI: 10.1371/Journal.Pgen.1005163  0.802
2015 Ivanov DK, Escott-Price V, Ziehm M, Magwire MM, Mackay TF, Partridge L, Thornton JM. Longevity GWAS Using the Drosophila Genetic Reference Panel. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 25922346 DOI: 10.1093/Gerona/Glv047  0.791
2015 Arya GH, Magwire MM, Huang W, Serrano-Negron YL, Mackay TF, Anholt RR. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Chemical Senses. 40: 233-43. PMID 25687947 DOI: 10.1093/Chemse/Bjv001  0.781
2015 Gaertner BE, Ruedi EA, McCoy LJ, Moore JM, Wolfner MF, Mackay TF. Heritable variation in courtship patterns in Drosophila melanogaster. G3 (Bethesda, Md.). 5: 531-9. PMID 25650358 DOI: 10.1534/G3.114.014811  0.444
2015 Mackay TF. Epistasis for quantitative traits in Drosophila. Methods in Molecular Biology (Clifton, N.J.). 1253: 47-70. PMID 25403527 DOI: 10.1007/978-1-4939-2155-3_4  0.541
2015 Dembeck LM, Böröczky K, Huang W, Schal C, Anholt RRH, Mackay TFC. Genetic architecture of natural variation in cuticular hydrocarbon composition in Drosophila melanogaster Elife. 4. DOI: 10.7554/eLife.09861.001  0.382
2014 Montgomery SL, Vorojeikina D, Huang W, Mackay TF, Anholt RR, Rand MD. Genome-wide association analysis of tolerance to methylmercury toxicity in Drosophila implicates myogenic and neuromuscular developmental pathways. Plos One. 9: e110375. PMID 25360876 DOI: 10.1371/Journal.Pone.0110375  0.41
2014 Zhou S, Mackay T, Anholt RR. Transcriptional and epigenetic responses to mating and aging in Drosophila melanogaster. Bmc Genomics. 15: 927. PMID 25344338 DOI: 10.1186/1471-2164-15-927  0.569
2014 Ellis LL, Huang W, Quinn AM, Ahuja A, Alfrejd B, Gomez FE, Hjelmen CE, Moore KL, Mackay TF, Johnston JS, Tarone AM. Intrapopulation genome size variation in D. melanogaster reflects life history variation and plasticity. Plos Genetics. 10: e1004522. PMID 25057905 DOI: 10.1371/Journal.Pgen.1004522  0.36
2014 Huang W, Massouras A, Inoue Y, Peiffer J, Ràmia M, Tarone AM, Turlapati L, Zichner T, Zhu D, Lyman RF, Magwire MM, Blankenburg K, Carbone MA, Chang K, Ellis LL, ... ... Mackay TF, et al. Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines. Genome Research. 24: 1193-208. PMID 24714809 DOI: 10.1101/Gr.171546.113  0.79
2014 Mackay TF. Epistasis and quantitative traits: using model organisms to study gene-gene interactions. Nature Reviews. Genetics. 15: 22-33. PMID 24296533 DOI: 10.1038/nrg3627  0.49
2013 Harbison ST, McCoy LJ, Mackay TF. Genome-wide association study of sleep in Drosophila melanogaster. Bmc Genomics. 14: 281. PMID 23617951 DOI: 10.1186/1471-2164-14-281  0.715
2013 Swarup S, Huang W, Mackay TF, Anholt RR. Analysis of natural variation reveals neurogenetic networks for Drosophila olfactory behavior. Proceedings of the National Academy of Sciences of the United States of America. 110: 1017-22. PMID 23277560 DOI: 10.1073/Pnas.1220168110  0.707
2013 Wilson RH, Lai CQ, Lyman RF, Mackay TF. Genomic response to selection for postponed senescence in Drosophila. Mechanisms of Ageing and Development. 134: 79-88. PMID 23262286 DOI: 10.1016/J.Mad.2012.11.003  0.651
2012 Massouras A, Waszak SM, Albarca-Aguilera M, Hens K, Holcombe W, Ayroles JF, Dermitzakis ET, Stone EA, Jensen JD, Mackay TF, Deplancke B. Genomic variation and its impact on gene expression in Drosophila melanogaster. Plos Genetics. 8: e1003055. PMID 23189034 DOI: 10.1371/Journal.Pgen.1003055  0.465
2012 Jumbo-Lucioni P, Bu S, Harbison ST, Slaughter JC, Mackay TF, Moellering DR, De Luca M. Nuclear genomic control of naturally occurring variation in mitochondrial function in Drosophila melanogaster. Bmc Genomics. 13: 659. PMID 23171078 DOI: 10.1186/1471-2164-13-659  0.723
2012 Huang W, Richards S, Carbone MA, Zhu D, Anholt RR, Ayroles JF, Duncan L, Jordan KW, Lawrence F, Magwire MM, Warner CB, Blankenburg K, Han Y, Javaid M, Jayaseelan J, ... ... Mackay TF, et al. Epistasis dominates the genetic architecture of Drosophila quantitative traits. Proceedings of the National Academy of Sciences of the United States of America. 109: 15553-9. PMID 22949659 DOI: 10.1073/Pnas.1213423109  0.788
2012 Anholt RR, Mackay TF. Genetics of aggression. Annual Review of Genetics. 46: 145-64. PMID 22934647 DOI: 10.1146/annurev-genet-110711-155514  0.487
2012 Jordan KW, Craver KL, Magwire MM, Cubilla CE, Mackay TF, Anholt RR. Genome-wide association for sensitivity to chronic oxidative stress in Drosophila melanogaster. Plos One. 7: e38722. PMID 22715409 DOI: 10.1371/Journal.Pone.0038722  0.75
2012 Weber AL, Khan GF, Magwire MM, Tabor CL, Mackay TF, Anholt RR. Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster. Plos One. 7: e34745. PMID 22496853 DOI: 10.1371/Journal.Pone.0034745  0.732
2012 Zhou S, Campbell TG, Stone EA, Mackay TF, Anholt RR. Phenotypic plasticity of the Drosophila transcriptome. Plos Genetics. 8: e1002593. PMID 22479193 DOI: 10.1371/Journal.Pgen.1002593  0.576
2012 Swarup S, Harbison ST, Hahn LE, Morozova TV, Yamamoto A, Mackay TF, Anholt RR. Extensive epistasis for olfactory behaviour, sleep and waking activity in Drosophila melanogaster. Genetics Research. 94: 9-20. PMID 22353245 DOI: 10.1017/S001667231200002X  0.813
2012 Morozova TV, Goldman D, Mackay TF, Anholt RR. The genetic basis of alcoholism: multiple phenotypes, many genes, complex networks. Genome Biology. 13: 239. PMID 22348705 DOI: 10.1186/Gb-2012-13-2-239  0.309
2012 Mackay TF, Richards S, Stone EA, Barbadilla A, Ayroles JF, Zhu D, Casillas S, Han Y, Magwire MM, Cridland JM, Richardson MF, Anholt RR, Barrón M, Bess C, Blankenburg KP, et al. The Drosophila melanogaster Genetic Reference Panel. Nature. 482: 173-8. PMID 22318601 DOI: 10.1038/Nature10811  0.804
2012 Weber A, Khan G, Magwire M, Tabor C, Anholt R, Mackay T. Genome-wide association mapping of resistance to oxidative stress in Drosophila identifies genes involved in complex disease F1000research. 3. DOI: 10.7490/F1000Research.1089991.1  0.74
2011 Ayroles JF, Laflamme BA, Stone EA, Wolfner MF, Mackay TF. Functional genome annotation of Drosophila seminal fluid proteins using transcriptional genetic networks. Genetics Research. 93: 387-95. PMID 22189604 DOI: 10.1017/S0016672311000346  0.436
2011 Zwarts L, Magwire MM, Carbone MA, Versteven M, Herteleer L, Anholt RR, Callaerts P, Mackay TF. Complex genetic architecture of Drosophila aggressive behavior. Proceedings of the National Academy of Sciences of the United States of America. 108: 17070-5. PMID 21949384 DOI: 10.1073/Pnas.1113877108  0.791
2011 Morozova TV, Mackay TF, Anholt RR. Transcriptional networks for alcohol sensitivity in Drosophila melanogaster. Genetics. 187: 1193-205. PMID 21270389 DOI: 10.1534/genetics.110.125229  0.367
2010 Arya GH, Weber AL, Wang P, Magwire MM, Negron YL, Mackay TF, Anholt RR. Natural variation, functional pleiotropy and transcriptional contexts of odorant binding protein genes in Drosophila melanogaster. Genetics. 186: 1475-85. PMID 20870963 DOI: 10.1534/Genetics.110.123166  0.787
2010 Magwire MM, Yamamoto A, Carbone MA, Roshina NV, Symonenko AV, Pasyukova EG, Morozova TV, Mackay TF. Quantitative and molecular genetic analyses of mutations increasing Drosophila life span. Plos Genetics. 6: e1001037. PMID 20686706 DOI: 10.1371/Journal.Pgen.1001037  0.752
2010 Desroches CE, Busto M, Riedl CA, Mackay TF, Sokolowski MB. Quantitative trait locus mapping of gravitaxis behaviour in Drosophila melanogaster. Genetics Research. 92: 167-74. PMID 20667161 DOI: 10.1017/S0016672310000194  0.384
2010 Rollmann SM, Wang P, Date P, West SA, Mackay TF, Anholt RR. Odorant receptor polymorphisms and natural variation in olfactory behavior in Drosophila melanogaster. Genetics. 186: 687-97. PMID 20628035 DOI: 10.1534/Genetics.110.119446  0.326
2010 Clowers KJ, Lyman RF, Mackay TF, Morgan TJ. Genetic variation in senescence marker protein-30 is associated with natural variation in cold tolerance in Drosophila. Genetics Research. 92: 103-13. PMID 20515514 DOI: 10.1017/S0016672310000108  0.451
2010 Jumbo-Lucioni P, Ayroles JF, Chambers MM, Jordan KW, Leips J, Mackay TF, De Luca M. Systems genetics analysis of body weight and energy metabolism traits in Drosophila melanogaster. Bmc Genomics. 11: 297. PMID 20459830 DOI: 10.1186/1471-2164-11-297  0.489
2010 Mackay TF. Mutations and quantitative genetic variation: lessons from Drosophila. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 365: 1229-39. PMID 20308098 DOI: 10.1098/rstb.2009.0315  0.512
2010 Zhou S, Mackay TF, Anholt RR. Tuning the chemosensory window: a fly's perspective. Fly. 4: 230-5. PMID 20305396 DOI: 10.4161/Fly.4.3.11627  0.466
2009 Yamamoto A, Anholt RR, MacKay TF. Epistatic interactions attenuate mutations affecting startle behaviour in Drosophila melanogaster. Genetics Research. 91: 373-82. PMID 19968911 DOI: 10.1017/S0016672309990279  0.452
2009 Zhou S, Stone EA, Mackay TF, Anholt RR. Plasticity of the chemoreceptor repertoire in Drosophila melanogaster. Plos Genetics. 5: e1000681. PMID 19816562 DOI: 10.1371/Journal.Pgen.1000681  0.516
2009 Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, Cho JH, Guttmacher AE, Kong A, Kruglyak L, Mardis E, ... ... Mackay TF, et al. Finding the missing heritability of complex diseases. Nature. 461: 747-53. PMID 19812666 DOI: 10.1038/Nature08494  0.336
2009 Mackay TF. Genetics. A-maize-ing diversity. Science (New York, N.Y.). 325: 688-9. PMID 19661410 DOI: 10.1126/science.1178420  0.369
2009 Morozova TV, Ayroles JF, Jordan KW, Duncan LH, Carbone MA, Lyman RF, Stone EA, Govindaraju DR, Ellison RC, Mackay TF, Anholt RR. Alcohol sensitivity in Drosophila: translational potential of systems genetics. Genetics. 183: 733-45, 1SI-12SI. PMID 19652175 DOI: 10.1534/Genetics.109.107490  0.348
2009 Edwards AC, Ayroles JF, Stone EA, Carbone MA, Lyman RF, Mackay TF. A transcriptional network associated with natural variation in Drosophila aggressive behavior. Genome Biology. 10: R76. PMID 19607677 DOI: 10.1186/Gb-2009-10-7-R76  0.657
2009 Mackay TF, Stone EA, Ayroles JF. The genetics of quantitative traits: challenges and prospects. Nature Reviews. Genetics. 10: 565-77. PMID 19584810 DOI: 10.1038/Nrg2612  0.483
2009 Edwards AC, Zwarts L, Yamamoto A, Callaerts P, Mackay TF. Mutations in many genes affect aggressive behavior in Drosophila melanogaster. Bmc Biology. 7: 29. PMID 19519879 DOI: 10.1186/1741-7007-7-29  0.608
2009 Harbison ST, Mackay TF, Anholt RR. Understanding the neurogenetics of sleep: progress from Drosophila. Trends in Genetics : Tig. 25: 262-9. PMID 19446357 DOI: 10.1016/J.Tig.2009.04.003  0.679
2009 Mackay TF. Q&A: Genetic analysis of quantitative traits. Journal of Biology. 8: 23. PMID 19435484 DOI: 10.1186/jbiol133  0.329
2009 Edwards AC, Mackay TF. Quantitative trait loci for aggressive behavior in Drosophila melanogaster. Genetics. 182: 889-97. PMID 19414563 DOI: 10.1534/Genetics.109.101691  0.654
2009 Flint J, Mackay TF. Genetic architecture of quantitative traits in mice, flies, and humans. Genome Research. 19: 723-33. PMID 19411597 DOI: 10.1101/gr.086660.108  0.487
2009 Harbison ST, Carbone MA, Ayroles JF, Stone EA, Lyman RF, Mackay TF. Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep. Nature Genetics. 41: 371-5. PMID 19234472 DOI: 10.1038/Ng.330  0.721
2009 Ayroles JF, Carbone MA, Stone EA, Jordan KW, Lyman RF, Magwire MM, Rollmann SM, Duncan LH, Lawrence F, Anholt RR, Mackay TF. Systems genetics of complex traits in Drosophila melanogaster. Nature Genetics. 41: 299-307. PMID 19234471 DOI: 10.1038/Ng.332  0.795
2009 Carbone MA, Ayroles JF, Yamamoto A, Morozova TV, West SA, Magwire MM, Mackay TF, Anholt RR. Overexpression of myocilin in the Drosophila eye activates the unfolded protein response: implications for glaucoma. Plos One. 4: e4216. PMID 19148291 DOI: 10.1371/Journal.Pone.0004216  0.692
2009 Mackay TF. The genetic architecture of complex behaviors: lessons from Drosophila. Genetica. 136: 295-302. PMID 18758968 DOI: 10.1007/s10709-008-9310-6  0.532
2008 Yamamoto A, Zwarts L, Callaerts P, Norga K, Mackay TF, Anholt RR. Neurogenetic networks for startle-induced locomotion in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 105: 12393-8. PMID 18713854 DOI: 10.1073/Pnas.0804889105  0.452
2008 Rollmann SM, Zwarts L, Edwards AC, Yamamoto A, Callaerts P, Norga K, Mackay TF, Anholt RR. Pleiotropic effects of Drosophila neuralized on complex behaviors and brain structure. Genetics. 179: 1327-36. PMID 18562639 DOI: 10.1534/Genetics.108.088435  0.601
2008 Sambandan D, Carbone MA, Anholt RR, Mackay TF. Phenotypic plasticity and genotype by environment interaction for olfactory behavior in Drosophila melanogaster. Genetics. 179: 1079-88. PMID 18505870 DOI: 10.1534/Genetics.108.086769  0.83
2007 Riedl CA, Riedl M, Mackay TF, Sokolowski MB. Genetic and behavioral analysis of natural variation in Drosophila melanogaster pupation position. Fly. 1: 23-32. PMID 18690058 DOI: 10.4161/Fly.3830  0.338
2007 Morozova TV, Anholt RR, Mackay TF. Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaster. Genome Biology. 8: R231. PMID 17973985 DOI: 10.1186/gb-2007-8-10-r231  0.326
2007 Lai CQ, Leips J, Zou W, Roberts JF, Wollenberg KR, Parnell LD, Zeng ZB, Ordovas JM, Mackay TF. Speed-mapping quantitative trait loci using microarrays. Nature Methods. 4: 839-41. PMID 17873888 DOI: 10.1038/Nmeth1084  0.318
2007 Wang P, Lyman RF, Shabalina SA, Mackay TF, Anholt RR. Association of polymorphisms in odorant-binding protein genes with variation in olfactory response to benzaldehyde in Drosophila. Genetics. 177: 1655-65. PMID 17720903 DOI: 10.1534/Genetics.107.079731  0.336
2007 Jordan KW, Carbone MA, Yamamoto A, Morgan TJ, Mackay TF. Quantitative genomics of locomotor behavior in Drosophila melanogaster. Genome Biology. 8: R172. PMID 17708775 DOI: 10.1186/gb-2007-8-8-r172  0.417
2007 Rollmann SM, Yamamoto A, Goossens T, Zwarts L, Callaerts-Végh Z, Callaerts P, Norga K, Mackay TF, Anholt RR. The early developmental gene Semaphorin 5c contributes to olfactory behavior in adult Drosophila. Genetics. 176: 947-56. PMID 17435226 DOI: 10.1534/Genetics.106.069781  0.363
2007 Mackay TF, Anholt RR. Ain't misbehavin' ? Genotype-environment interactions and the genetics of behavior. Trends in Genetics : Tig. 23: 311-4. PMID 17418441 DOI: 10.1016/j.tig.2007.03.013  0.36
2007 Lai CQ, Parnell LD, Lyman RF, Ordovas JM, Mackay TF. Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping. Mechanisms of Ageing and Development. 128: 237-49. PMID 17196240 DOI: 10.1016/J.Mad.2006.12.003  0.357
2006 Edwards AC, Rollmann SM, Morgan TJ, Mackay TF. Quantitative genomics of aggressive behavior in Drosophila melanogaster. Plos Genetics. 2: e154. PMID 17044737 DOI: 10.1371/Journal.Pgen.0020154  0.607
2006 Sambandan D, Yamamoto A, Fanara JJ, Mackay TF, Anholt RR. Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster. Genetics. 174: 1349-63. PMID 17028343 DOI: 10.1534/Genetics.106.060574  0.825
2006 Rollmann SM, Magwire MM, Morgan TJ, Ozsoy ED, Yamamoto A, Mackay TF, Anholt RR. Pleiotropic fitness effects of the Tre1-Gr5a region in Drosophila melanogaster. Nature Genetics. 38: 824-9. PMID 16783380 DOI: 10.1038/Ng1823  0.754
2006 Jordan KW, Morgan TJ, Mackay TF. Quantitative trait loci for locomotor behavior in Drosophila melanogaster. Genetics. 174: 271-84. PMID 16783013 DOI: 10.1534/genetics.106.058099  0.449
2006 Mackay TF, Anholt RR. Of flies and man: Drosophila as a model for human complex traits. Annual Review of Genomics and Human Genetics. 7: 339-67. PMID 16756480 DOI: 10.1146/annurev.genom.7.080505.115758  0.468
2006 Wilson RH, Morgan TJ, Mackay TF. High-resolution mapping of quantitative trait loci affecting increased life span in Drosophila melanogaster. Genetics. 173: 1455-63. PMID 16702433 DOI: 10.1534/Genetics.105.055111  0.658
2006 Carbone MA, Jordan KW, Lyman RF, Harbison ST, Leips J, Morgan TJ, DeLuca M, Awadalla P, Mackay TF. Phenotypic variation and natural selection at catsup, a pleiotropic quantitative trait gene in Drosophila. Current Biology : Cb. 16: 912-9. PMID 16682353 DOI: 10.1016/J.Cub.2006.03.051  0.793
2006 Moehring AJ, Llopart A, Elwyn S, Coyne JA, Mackay TF. The genetic basis of postzygotic reproductive isolation between Drosophila santomea and D. yakuba due to hybrid male sterility. Genetics. 173: 225-33. PMID 16510788 DOI: 10.1534/Genetics.105.052985  0.316
2006 Leips J, Gilligan P, Mackay TF. Quantitative trait loci with age-specific effects on fecundity in Drosophila melanogaster. Genetics. 172: 1595-605. PMID 16272414 DOI: 10.1534/genetics.105.048520  0.358
2005 Mackay TF, Lyman RF. Drosophila bristles and the nature of quantitative genetic variation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 360: 1513-27. PMID 16108138 DOI: 10.1098/Rstb.2005.1672  0.488
2005 Carbone MA, Llopart A, deAngelis M, Coyne JA, Mackay TF. Quantitative trait loci affecting the difference in pigmentation between Drosophila yakuba and D. santomea. Genetics. 171: 211-25. PMID 15972457 DOI: 10.1534/Genetics.105.044412  0.317
2005 Wayne ML, Korol A, Mackay TF. Microclinal variation for ovariole number and body size in Drosophila melanogaster in 'Evolution Canyon'. Genetica. 123: 263-70. PMID 15954497 DOI: 10.1007/S10709-004-5056-Y  0.376
2005 Mackay TF, Lyman RF, Lawrence F. Polygenic mutation in Drosophila melanogaster: Mapping spontaneous mutations affecting sensory bristle number. Genetics. 170: 1723-35. PMID 15944368 DOI: 10.1534/Genetics.104.032581  0.356
2005 Mackay TF, Heinsohn SL, Lyman RF, Moehring AJ, Morgan TJ, Rollmann SM. Genetics and genomics of Drosophila mating behavior. Proceedings of the National Academy of Sciences of the United States of America. 102: 6622-9. PMID 15851659 DOI: 10.1073/Pnas.0501986102  0.434
2005 Harbison ST, Chang S, Kamdar KP, Mackay TF. Quantitative genomics of starvation stress resistance in Drosophila. Genome Biology. 6: R36. PMID 15833123 DOI: 10.1186/gb-2005-6-4-r36  0.778
2005 Rollmann SM, Mackay TF, Anholt RR. Pinocchio, a novel protein expressed in the antenna, contributes to olfactory behavior in Drosophila melanogaster. Journal of Neurobiology. 63: 146-58. PMID 15719418 DOI: 10.1002/Neu.20123  0.319
2004 Anholt RR, Mackay TF. Quantitative genetic analyses of complex behaviours in Drosophila. Nature Reviews. Genetics. 5: 838-49. PMID 15520793 DOI: 10.1038/nrg1472  0.434
2004 Pasyukova EG, Roshina NV, Mackay TF. Shuttle craft: a candidate quantitative trait gene for Drosophila lifespan. Aging Cell. 3: 297-307. PMID 15379853 DOI: 10.1111/J.1474-9728.2004.00114.X  0.501
2004 Moehring AJ, Li J, Schug MD, Smith SG, deAngelis M, Mackay TF, Coyne JA. Quantitative trait loci for sexual isolation between Drosophila simulans and D. mauritiana. Genetics. 167: 1265-74. PMID 15280240 DOI: 10.1534/genetics.103.024364  0.317
2004 Moehring AJ, Mackay TF. The quantitative genetic basis of male mating behavior in Drosophila melanogaster. Genetics. 167: 1249-63. PMID 15280239 DOI: 10.1534/genetics.103.024372  0.303
2004 Mackay TF. The genetic architecture of quantitative traits: lessons from Drosophila. Current Opinion in Genetics & Development. 14: 253-7. PMID 15172667 DOI: 10.1016/j.gde.2004.04.003  0.42
2004 Harbison ST, Yamamoto AH, Fanara JJ, Norga KK, Mackay TF. Quantitative trait loci affecting starvation resistance in Drosophila melanogaster. Genetics. 166: 1807-23. PMID 15126400 DOI: 10.1534/Genetics.166.4.1807  0.796
2004 Mackay TF. Methods for genetic dissection of complex traits. Science of Aging Knowledge Environment : Sage Ke. 2004: pe17. PMID 15115850 DOI: 10.1126/sageke.2004.17.pe17  0.358
2004 Genissel A, Pastinen T, Dowell A, Mackay TF, Long AD. No evidence for an association between common nonsynonymous polymorphisms in delta and bristle number variation in natural and laboratory populations of Drosophila melanogaster. Genetics. 166: 291-306. PMID 15020426 DOI: 10.1534/genetics.166.1.291  0.356
2004 Geiger-Thornsberry GL, Mackay TF. Quantitative trait loci affecting natural variation in Drosophila longevity. Mechanisms of Ageing and Development. 125: 179-89. PMID 15013662 DOI: 10.1016/j.mad.2003.12.008  0.441
2003 Ungerer MC, Halldorsdottir SS, Purugganan MD, Mackay TF. Genotype-environment interactions at quantitative trait loci affecting inflorescence development in Arabidopsis thaliana. Genetics. 165: 353-65. PMID 14504242  0.383
2003 Weinig C, Dorn LA, Kane NC, German ZM, Halldorsdottir SS, Ungerer MC, Toyonaga Y, Mackay TF, Purugganan MD, Schmitt J. Heterogeneous selection at specific loci in natural environments in Arabidopsis thaliana. Genetics. 165: 321-9. PMID 14504239  0.433
2003 Anholt RR, Dilda CL, Chang S, Fanara JJ, Kulkarni NH, Ganguly I, Rollmann SM, Kamdar KP, Mackay TF. The genetic architecture of odor-guided behavior in Drosophila: epistasis and the transcriptome. Nature Genetics. 35: 180-4. PMID 12958599 DOI: 10.1038/Ng1240  0.817
2003 Norga KK, Gurganus MC, Dilda CL, Yamamoto A, Lyman RF, Patel PH, Rubin GM, Hoskins RA, Mackay TF, Bellen HJ. Quantitative analysis of bristle number in Drosophila mutants identifies genes involved in neural development. Current Biology : Cb. 13: 1388-96. PMID 12932322 DOI: 10.1016/S0960-9822(03)00546-3  0.824
2003 Ganguly I, Mackay TF, Anholt RR. Scribble is essential for olfactory behavior in Drosophila melanogaster. Genetics. 164: 1447-57. PMID 12930751  0.688
2003 De Luca M, Roshina NV, Geiger-Thornsberry GL, Lyman RF, Pasyukova EG, Mackay TF. Dopa decarboxylase (Ddc) affects variation in Drosophila longevity. Nature Genetics. 34: 429-33. PMID 12881721 DOI: 10.1038/Ng1218  0.44
2002 Lyman RF, Nevo E, Mackay TF. Variation in Drosophila sensory bristle number at 'Evolution Canyon'. Genetical Research. 80: 215-23. PMID 12688660 DOI: 10.1017/S0016672302005876  0.36
2002 Weinig C, Ungerer MC, Dorn LA, Kane NC, Toyonaga Y, Halldorsdottir SS, Mackay TF, Purugganan MD, Schmitt J. Novel loci control variation in reproductive timing in Arabidopsis thaliana in natural environments. Genetics. 162: 1875-84. PMID 12524356  0.353
2002 Dilda CL, Mackay TF. The genetic architecture of Drosophila sensory bristle number. Genetics. 162: 1655-74. PMID 12524340  0.816
2002 Fanara JJ, Robinson KO, Rollmann SM, Anholt RR, Mackay TF. Vanaso is a candidate quantitative trait gene for Drosophila olfactory behavior. Genetics. 162: 1321-8. PMID 12454076  0.496
2002 Gibson G, Mackay TF. Enabling population and quantitative genomics. Genetical Research. 80: 1-6. PMID 12448852 DOI: 10.1017/S0016672302005839  0.375
2002 Robin C, Lyman RF, Long AD, Langley CH, Mackay TF. hairy: A quantitative trait locus for drosophila sensory bristle number. Genetics. 162: 155-64. PMID 12242230  0.465
2002 Leips J, Mackay TF. The complex genetic architecture of Drosophila life span. Experimental Aging Research. 28: 361-90. PMID 12227919 DOI: 10.1080/03610730290080399  0.395
2002 Geiger-Thornsberry GL, Mackay TF. Association of single-nucleotide polymorphisms at the Delta locus with genotype by environment interaction for sensory bristle number in drosophila Melanogaster. Genetical Research. 79: 211-8. PMID 12220128 DOI: 10.1017/S0016672302005621  0.338
2002 Ungerer MC, Halldorsdottir SS, Modliszewski JL, Mackay TF, Purugganan MD. Quantitative trait loci for inflorescence development in Arabidopsis thaliana. Genetics. 160: 1133-51. PMID 11901129  0.47
2002 Mackay TF. The nature of quantitative genetic variation for Drosophila longevity. Mechanisms of Ageing and Development. 123: 95-104. PMID 11718804 DOI: 10.1016/S0047-6374(01)00330-X  0.409
2001 Wayne ML, Hackett JB, Dilda CL, Nuzhdin SV, Pasyukova EG, Mackay TF. Quantitative trait locus mapping of fitness-related traits in Drosophila melanogaster. Genetical Research. 77: 107-16. PMID 11279827 DOI: 10.1017/S0016672300004894  0.809
2001 Anholt RR, Fanara JJ, Fedorowicz GM, Ganguly I, Kulkarni NH, Mackay TF, Rollmann SM. Functional genomics of odor-guided behavior in Drosophila melanogaster. Chemical Senses. 26: 215-21. PMID 11238254 DOI: 10.1093/Chemse/26.2.215  0.735
1999 Nuzhdin SV, Dilda CL, Mackay TF. The genetic architecture of selection response. Inferences from fine-scale mapping of bristle number quantitative trait loci in Drosophila melanogaster. Genetics. 153: 1317-31. PMID 10545462  0.807
1997 Wayne ML, Hackett JB, Mackay TFC. QUANTITATIVE GENETICS OF OVARIOLE NUMBER IN DROSOPHILA MELANOGASTER. I. SEGREGATING VARIATION AND FITNESS. Evolution; International Journal of Organic Evolution. 51: 1156-1163. PMID 28565484 DOI: 10.1111/J.1558-5646.1997.Tb03963.X  0.423
1997 Nuzhdin SV, Pasyukova EG, Dilda CL, Zeng ZB, Mackay TF. Sex-specific quantitative trait loci affecting longevity in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 94: 9734-9. PMID 9275193 DOI: 10.1073/Pnas.94.18.9734  0.816
1996 Fry JD, Heinsohn SL, Mackay TFC. THE CONTRIBUTION OF NEW MUTATIONS TO GENOTYPE-ENVIRONMENT INTERACTION FOR FITNESS IN DROSOPHILA MELANOGASTER. Evolution; International Journal of Organic Evolution. 50: 2316-2327. PMID 28565671 DOI: 10.1111/j.1558-5646.1996.tb03619.x  0.358
1992 Mackay TFC, Lyman RF, Jackson MS, Terzian C, Hill WG. POLYGENIC MUTATION IN DROSOPHILA MELANOGASTER: ESTIMATES FROM DIVERGENCE AMONG INBRED STRAINS. Evolution; International Journal of Organic Evolution. 46: 300-316. PMID 28564027 DOI: 10.1111/J.1558-5646.1992.Tb02039.X  0.329
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