Year |
Citation |
Score |
2016 |
Feldman HC, Tong M, Wang L, Meza-Acevedo R, Gobillot TA, Lebedev I, Gliedt MJ, Hari SB, Mitra AK, Backes BJ, Papa FR, Seeliger MA, Maly DJ. Structural and Functional Analysis of the Allosteric Inhibition of IRE1α with ATP-Competitive Ligands. Acs Chemical Biology. PMID 27227314 DOI: 10.1021/Acschembio.5B00940 |
0.504 |
|
2014 |
Ghosh R, Wang L, Wang ES, Perera BG, Igbaria A, Morita S, Prado K, Thamsen M, Caswell D, Macias H, Weiberth KF, Gliedt MJ, Alavi MV, Hari SB, Mitra AK, ... ... Backes BJ, et al. Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress. Cell. 158: 534-48. PMID 25018104 DOI: 10.1016/J.Cell.2014.07.002 |
0.494 |
|
2012 |
Wang L, Perera BG, Hari SB, Bhhatarai B, Backes BJ, Seeliger MA, Schürer SC, Oakes SA, Papa FR, Maly DJ. Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors. Nature Chemical Biology. 8: 982-9. PMID 23086298 DOI: 10.1038/Nchembio.1094 |
0.51 |
|
2002 |
Maly DJ, Leonetti F, Backes BJ, Dauber DS, Harris JL, Craik CS, Ellman JA. Expedient solid-phase synthesis of fluorogenic protease substrates using the 7-amino-4-carbamoylmethylcoumarin (ACC) fluorophore. The Journal of Organic Chemistry. 67: 910-5. PMID 11856036 DOI: 10.1021/Jo016140O |
0.683 |
|
2001 |
Harris JL, Niles A, Burdick K, Maffitt M, Backes BJ, Ellman JA, Kuntz I, Haak-Frendscho M, Craik CS. Definition of the extended substrate specificity determinants for beta-tryptases I and II. The Journal of Biological Chemistry. 276: 34941-7. PMID 11438529 DOI: 10.1074/Jbc.M102997200 |
0.479 |
|
2000 |
Harris JL, Backes BJ, Leonetti F, Mahrus S, Ellman JA, Craik CS. Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries. Proceedings of the National Academy of Sciences of the United States of America. 97: 7754-9. PMID 10869434 DOI: 10.1073/Pnas.140132697 |
0.652 |
|
2000 |
Backes BJ, Harris JL, Leonetti F, Craik CS, Ellman JA. Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin. Nature Biotechnology. 18: 187-93. PMID 10657126 DOI: 10.1038/72642 |
0.63 |
|
1999 |
Backes BJ, Dragoli DR, Ellman JA. Chiral N-Acyl-tert-butanesulfinamides: The "Safety-Catch" Principle Applied to Diastereoselective Enolate Alkylations. The Journal of Organic Chemistry. 64: 5472-5478. PMID 11674609 DOI: 10.1021/Jo990271W |
0.658 |
|
1999 |
Backes BJ, Dragoli DR, Ellman JA. Chiral N-acyl-tert-butanesulfinamides: The 'safety-catch' principle applied to diastereoselective enolate alkylations Journal of Organic Chemistry. 64: 5472-5478. DOI: 10.1021/jo990271w |
0.675 |
|
1999 |
Backes BJ, Ellman JA. An alkanesulfonamide 'safety-catch' linker for solid-phase synthesis Journal of Organic Chemistry. 64: 2322-2330. DOI: 10.1021/Jo981990Y |
0.549 |
|
1998 |
Cogan DA, Liu G, Kim K, Backes BJ, Ellman JA. Catalytic asymmetric oxidation of tert-butyl disulfide. Synthesis of tert-butanesulfinamides, tert-butyl sulfoxides, and tert-butanesulfinimines Journal of the American Chemical Society. 120: 8011-8019. DOI: 10.1021/Ja9809206 |
0.51 |
|
1997 |
Backes BJ, Ellman JA. Solid support linker strategies. Current Opinion in Chemical Biology. 1: 86-93. PMID 9667836 DOI: 10.1016/S1367-5931(97)80113-5 |
0.467 |
|
1996 |
Backes BJ, Virgilio AA, Ellman JA. Activation Method to Prepare a Highly Reactive Acylsulfonamide “Safety-Catch” Linker for Solid-Phase Synthesis1 Journal of the American Chemical Society. 118: 3055-3056. DOI: 10.1021/Ja9535165 |
0.451 |
|
1994 |
Backes BJ, Ellman JA. Carbon-Carbon Bond-Forming Methods on Solid Support. Utilization of Kenner's "Safety-Catch" Linker Journal of the American Chemical Society. 116: 11171-11172. DOI: 10.1021/Ja00103A048 |
0.399 |
|
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