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Simmon P. Brooks - Publications

Affiliations: 
2002-2016 School of Biosciences Cardiff University, Cardiff, Wales, United Kingdom 
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65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Muha V, Williamson R, Hills R, McNeilly AD, McWilliams TG, Alonso J, Schimpl M, Leney AC, Heck AJR, Sutherland C, Read KD, McCrimmon RJ, Brooks SP, van Aalten DMF. Loss of CRMP2 O-GlcNAcylation leads to reduced novel object recognition performance in mice. Open Biology. 9: 190192. PMID 31771416 DOI: 10.1098/Rsob.190192  0.666
2018 McWilliams TG, Barini E, Pohjolan-Pirhonen R, Brooks SP, Singh F, Burel S, Balk K, Kumar A, Montava-Garriga L, Prescott AR, Hassoun SM, Mouton-Liger F, Ball G, Hills R, Knebel A, et al. Phosphorylation of Parkin at serine 65 is essential for its activation . Open Biology. 8. PMID 30404819 DOI: 10.1098/Rsob.180108  0.713
2018 Dunnett SB, Brooks SP. Motor Assessment in Huntington's Disease Mice. Methods in Molecular Biology (Clifton, N.J.). 1780: 121-141. PMID 29856017 DOI: 10.1007/978-1-4939-7825-0_7  0.542
2018 Harrison DJ, Roberton VH, Vinh NN, Brooks SP, Dunnett SB, Rosser AE. The Effect of Tissue Preparation and Donor Age on Striatal Graft Morphology in the Mouse. Cell Transplantation. 27: 230-244. PMID 29637815 DOI: 10.1177/0963689717744788  0.415
2018 McWilliams TG, Prescott AR, Montava-Garriga L, Ball G, Singh F, Barini E, Muqit MMK, Brooks SP, Ganley IG. Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand. Cell Metabolism. PMID 29337137 DOI: 10.1016/j.cmet.2017.12.008  0.661
2017 Bragg RM, Coffey SR, Weston RM, Ament SA, Cantle JP, Minnig S, Funk CC, Shuttleworth DD, Woods EL, Sullivan BR, Jones L, Glickenhaus A, Anderson JS, Anderson MD, Dunnett SB, ... ... Brooks SP, et al. Corrigendum: Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.Htt(Q111/+) model of Huntington's disease. Scientific Reports. 7: 44960. PMID 28350386 DOI: 10.1038/srep44960  0.47
2017 Bragg RM, Coffey SR, Weston RM, Ament SA, Cantle JP, Minnig S, Funk CC, Shuttleworth DD, Woods EL, Sullivan BR, Jones L, Glickenhaus A, Anderson JS, Anderson MD, Dunnett SB, ... ... Brooks SP, et al. Motivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.Htt(Q111/+) model of Huntington's disease. Scientific Reports. 7: 41570. PMID 28176805 DOI: 10.1038/Srep41570  0.523
2016 Bowles KR, Brooks SP, Hughes AC, Dunnett SB, Jones L. Correction: Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdhQ111 Model of HD. Plos One. 11: e0165069. PMID 27736977 DOI: 10.1371/journal.pone.0165069  0.364
2016 Yhnell E, Dunnett SB, Brooks SP. A Longitudinal Operant Assessment of Cognitive and Behavioural Changes in the HdhQ111 Mouse Model of Huntington's Disease. Plos One. 11: e0164072. PMID 27701442 DOI: 10.1371/Journal.Pone.0164072  0.798
2016 Yhnell E, Dunnett SB, Brooks SP. A Longitudinal Motor Characterisation of the HdhQ111 Mouse Model of Huntington's Disease. Journal of Huntington's Disease. PMID 27258586 DOI: 10.3233/Jhd-160191  0.78
2016 Bayram-Weston Z, Jones L, Dunnett SB, Brooks SP. Comparison of mHTT Antibodies in Huntington's Disease Mouse Models Reveal Specific Binding Profiles and Steady-State Ubiquitin Levels with Disease Development. Plos One. 11: e0155834. PMID 27196694 DOI: 10.1371/journal.pone.0155834  0.486
2016 Yhnell E, Lelos MJ, Dunnett SB, Brooks SP. Cognitive training modifies disease symptoms in a mouse model of Huntington's disease. Experimental Neurology. PMID 27163546 DOI: 10.1016/J.Expneurol.2016.05.008  0.788
2016 Fears K, Stone T, Elliston L, Bayram-Weston Z, Harrison D, Dunnett SB, Jones L, Brooks S. C4 Motivation and reward seeking in HD mouse lines: possible association with ventral striatal mHTT load and dopamine receptor loss Journal of Neurology, Neurosurgery & Psychiatry. 87: A28.1-A28. DOI: 10.1136/Jnnp-2016-314597.84  0.371
2016 Stone T, Elliston L, Brooks S, Holmans P, Dunnett SB, Jones L. B12 Characterising gene expression changes in mouse lines with varying repeat lengths in HTT Journal of Neurology, Neurosurgery & Psychiatry. 87: A13.1-A13. DOI: 10.1136/Jnnp-2016-314597.43  0.383
2016 Yhnell E, Lelos M, Dunnett S, Brooks S. L30 Cognitive training improves disease symptoms in a mouse model of huntington’s disease Journal of Neurology, Neurosurgery & Psychiatry. 87: A100.2-A101. DOI: 10.1136/Jnnp-2016-314597.285  0.779
2015 Bayram-Weston Z, Stone TC, Giles P, Elliston L, Janghra N, Higgs GV, Holmans PA, Dunnett SB, Brooks SP, Jones L. Similar striatal gene expression profiles in the striatum of the YAC128 and HdhQ150 mouse models of Huntington's disease are not reflected in mutant Huntingtin inclusion prevalence. Bmc Genomics. 16: 1079. PMID 26691352 DOI: 10.1186/s12864-015-2251-4  0.484
2015 Bowles KR, Brooks SP, Dunnett SB, Jones L. Huntingtin Subcellular Localisation Is Regulated by Kinase Signalling Activity in the StHdhQ111 Model of HD. Plos One. 10: e0144864. PMID 26660732 DOI: 10.1371/journal.pone.0144864  0.444
2015 Bayram-Weston Z, Olsen E, Harrison DJ, Dunnett SB, Brooks SP. Optimising Golgi-Cox staining for use with perfusion-fixed brain tissue validated in the zQ175 mouse model of Huntington's disease. Journal of Neuroscience Methods. PMID 26459195 DOI: 10.1016/j.jneumeth.2015.09.033  0.417
2015 Steventon JJ, Harrison DJ, Trueman RC, Rosser AE, Jones DK, Brooks SP. In Vivo MRI Evidence that Neuropathology is Attenuated by Cognitive Enrichment in the Yac128 Huntington's Disease Mouse Model. Journal of Huntington's Disease. 4: 149-60. PMID 26397896 DOI: 10.3233/Jhd-150147  0.337
2015 Yhnell E, Dunnett SB, Brooks SP. The utilisation of operant delayed matching and non-matching to position for probing cognitive flexibility and working memory in mouse models of Huntington's disease. Journal of Neuroscience Methods. PMID 26321735 DOI: 10.1016/J.Jneumeth.2015.08.022  0.786
2015 Brooks SP, Dunnett SB. Mouse Models of Huntington's Disease. Current Topics in Behavioral Neurosciences. 22: 101-33. PMID 24357436 DOI: 10.1007/7854_2013_256  0.535
2014 Hughes AC, Mort M, Elliston L, Thomas RM, Brooks SP, Dunnett SB, Jones L. Identification of novel alternative splicing events in the huntingtin gene and assessment of the functional consequences using structural protein homology modelling. Journal of Molecular Biology. 426: 1428-38. PMID 24389360 DOI: 10.1016/j.jmb.2013.12.028  0.462
2014 Yhnell E, Dunnett S, Brooks S. C04 A Longitudinal Behavioural Characterisation of the HDHQ111 Mouse Model of Huntington's Disease Journal of Neurology, Neurosurgery & Psychiatry. 85: A26-A26. DOI: 10.1136/Jnnp-2014-309032.77  0.805
2014 Harrison D, Patel Y, Tear A, Jones L, Dunnett S, Brooks S. C03 Longitudinal Analysis Of The Behavioural Phenotype In The Zq175 (c57bl/6j) Huntington's Disease Mouse Line Journal of Neurology, Neurosurgery & Psychiatry. 85: A25-A26. DOI: 10.1136/jnnp-2014-309032.76  0.616
2014 Bayram-Weston Z, Jones L, Dunnett S, Brooks S. B09 Differential Sensitivity of Aggregate Markers in HDHQ140 Mouse Model Journal of Neurology, Neurosurgery & Psychiatry. 85: A11-A12. DOI: 10.1136/jnnp-2014-309032.37  0.503
2013 Harrison DJ, Busse M, Openshaw R, Rosser AE, Dunnett SB, Brooks SP. Exercise attenuates neuropathology and has greater benefit on cognitive than motor deficits in the R6/1 Huntington's disease mouse model. Experimental Neurology. 248: 457-69. PMID 23911978 DOI: 10.1016/J.Expneurol.2013.07.014  0.522
2013 Peters OM, Shelkovnikova T, Tarasova T, Springe S, Kukharsky MS, Smith GA, Brooks S, Kozin SA, Kotelevtsev Y, Bachurin SO, Ninkina N, Buchman VL. Chronic administration of Dimebon does not ameliorate amyloid-β pathology in 5xFAD transgenic mice. Journal of Alzheimer's Disease : Jad. 36: 589-96. PMID 23645096 DOI: 10.3233/Jad-130071  0.704
2013 Brooks SP, Dunnett SB. Cognitive deficits in animal models of basal ganglia disorders. Brain Research Bulletin. 92: 29-40. PMID 22588013 DOI: 10.1016/j.brainresbull.2012.04.011  0.571
2012 Brooks SP, Trueman RC, Dunnett SB. Assessment of Motor Coordination and Balance in Mice Using the Rotarod, Elevated Bridge, and Footprint Tests. Current Protocols in Mouse Biology. 2: 37-53. PMID 26069004 DOI: 10.1002/9780470942390.mo110165  0.524
2012 Trueman RC, Dunnett SB, Jones L, Brooks SP. Five choice serial reaction time performance in the HdhQ92 mouse model of Huntington's disease. Brain Research Bulletin. 88: 163-70. PMID 22085744 DOI: 10.1016/j.brainresbull.2011.10.019  0.566
2012 Brooks SP, Jones L, Dunnett SB. Comparative analysis of pathology and behavioural phenotypes in mouse models of Huntington's disease. Brain Research Bulletin. 88: 81-93. PMID 22004616 DOI: 10.1016/j.brainresbull.2011.10.002  0.521
2012 Giles P, Elliston L, Higgs GV, Brooks SP, Dunnett SB, Jones L. Longitudinal analysis of gene expression and behaviour in the HdhQ150 mouse model of Huntington's disease. Brain Research Bulletin. 88: 199-209. PMID 22001697 DOI: 10.1016/j.brainresbull.2011.10.001  0.516
2012 Fielding SA, Brooks SP, Klein A, Bayram-Weston Z, Jones L, Dunnett SB. Profiles of motor and cognitive impairment in the transgenic rat model of Huntington's disease. Brain Research Bulletin. 88: 223-36. PMID 21963415 DOI: 10.1016/j.brainresbull.2011.09.011  0.577
2012 Bowles KR, Brooks SP, Dunnett SB, Jones L. Gene expression and behaviour in mouse models of HD. Brain Research Bulletin. 88: 276-84. PMID 21854837 DOI: 10.1016/j.brainresbull.2011.07.021  0.5
2012 Bayram-Weston Z, Jones L, Dunnett SB, Brooks SP. Light and electron microscopic characterization of the evolution of cellular pathology in the R6/1 Huntington's disease transgenic mice. Brain Research Bulletin. 88: 104-12. PMID 21801812 DOI: 10.1016/j.brainresbull.2011.07.009  0.491
2012 Brooks SP, Jones L, Dunnett SB. Longitudinal analyses of operant performance on the serial implicit learning task (SILT) in the YAC128 Huntington's disease mouse line. Brain Research Bulletin. 88: 130-6. PMID 21763407 DOI: 10.1016/j.brainresbull.2011.06.008  0.607
2012 Brooks SP, Janghra N, Higgs GV, Bayram-Weston Z, Heuer A, Jones L, Dunnett SB. Selective cognitive impairment in the YAC128 Huntington's disease mouse. Brain Research Bulletin. 88: 121-9. PMID 21624441 DOI: 10.1016/J.Brainresbull.2011.05.010  0.666
2012 Bayram-Weston Z, Jones L, Dunnett SB, Brooks SP. Light and electron microscopic characterization of the evolution of cellular pathology in YAC128 Huntington's disease transgenic mice. Brain Research Bulletin. 88: 137-47. PMID 21620935 DOI: 10.1016/j.brainresbull.2011.05.005  0.53
2012 Dunnett SB, Heuer A, Lelos M, Brooks SP, Rosser AE. Bilateral striatal lesions disrupt performance in an operant delayed reinforcement task in rats. Brain Research Bulletin. 88: 251-60. PMID 21515345 DOI: 10.1016/J.Brainresbull.2011.04.002  0.625
2012 Bayram-Weston Z, Jones L, Dunnett SB, Brooks SP. Light and electron microscopic characterization of the evolution of cellular pathology in HdhQ92 Huntington's disease knock-in mice. Brain Research Bulletin. 88: 171-81. PMID 21513775 DOI: 10.1016/j.brainresbull.2011.03.013  0.544
2012 Bayram-Weston Z, Torres EM, Jones L, Dunnett SB, Brooks SP. Light and electron microscopic characterization of the evolution of cellular pathology in the Hdh(CAG)150 Huntington's disease knock-in mouse. Brain Research Bulletin. 88: 189-98. PMID 21511013 DOI: 10.1016/j.brainresbull.2011.03.014  0.547
2012 Trueman RC, Dunnett SB, Brooks SP. Operant-based instrumental learning for analysis of genetically modified models of Huntington's disease. Brain Research Bulletin. 88: 261-75. PMID 21440048 DOI: 10.1016/j.brainresbull.2011.03.015  0.548
2012 Trueman RC, Jones L, Dunnett SB, Brooks SP. Early onset deficits on the delayed alternation task in the Hdh(Q92) knock-in mouse model of Huntington's disease. Brain Research Bulletin. 88: 156-62. PMID 21440047 DOI: 10.1016/j.brainresbull.2011.03.012  0.592
2012 Deschepper M, Hoogendoorn B, Brooks S, Dunnett SB, Jones L. Proteomic changes in the brains of Huntington's disease mouse models reflect pathology and implicate mitochondrial changes. Brain Research Bulletin. 88: 210-22. PMID 21272615 DOI: 10.1016/j.brainresbull.2011.01.012  0.475
2012 Brooks SP, Janghra N, Workman VL, Bayram-Weston Z, Jones L, Dunnett SB. Longitudinal analysis of the behavioural phenotype in R6/1 (C57BL/6J) Huntington's disease transgenic mice. Brain Research Bulletin. 88: 94-103. PMID 21272613 DOI: 10.1016/j.brainresbull.2011.01.010  0.551
2012 Dunnett SB, Fuller A, Rosser AE, Brooks SP. A novel extended sequence learning task (ESLeT) for rodents: validation and the effects of amphetamine, scopolamine and striatal lesions. Brain Research Bulletin. 88: 237-50. PMID 20969933 DOI: 10.1016/J.Brainresbull.2010.10.005  0.465
2012 Brooks S, Higgs G, Janghra N, Jones L, Dunnett SB. Longitudinal analysis of the behavioural phenotype in YAC128 (C57BL/6J) Huntington's disease transgenic mice. Brain Research Bulletin. 88: 113-20. PMID 20460143 DOI: 10.1016/j.brainresbull.2010.05.005  0.56
2012 Brooks S, Higgs G, Jones L, Dunnett SB. Longitudinal analysis of the behavioural phenotype in Hdh(CAG)150 Huntington's disease knock-in mice. Brain Research Bulletin. 88: 182-8. PMID 20457230 DOI: 10.1016/j.brainresbull.2010.05.004  0.604
2012 Brooks S, Higgs G, Jones L, Dunnett SB. Longitudinal analysis of the behavioural phenotype in HdhQ92 Huntington's disease knock-in mice. Brain Research Bulletin. 88: 148-55. PMID 20457229 DOI: 10.1016/j.brainresbull.2010.05.003  0.54
2012 Bayram-Weston Z, Jones L, Dunnett S, Brooks S. B08 Differential sensitivity of aggregate markers in HdhQ150 and YAC128 HD mouse models Journal of Neurology, Neurosurgery & Psychiatry. 83: A8.1-A8. DOI: 10.1136/jnnp-2012-303524.24  0.501
2010 Twohig JP, Roberts MI, Gavalda N, Rees-Taylor EL, Giralt A, Adams D, Brooks SP, Bull MJ, Calder CJ, Cuff S, Yong AA, Alberch J, Davies A, Dunnett SB, Tolkovsky AM, et al. Age-dependent maintenance of motor control and corticostriatal innervation by death receptor 3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3782-92. PMID 20220013 DOI: 10.1523/Jneurosci.1928-09.2010  0.504
2010 Brooks S, Jones L, Dunnett SB. A29 Frontostriatal pathology in the (C57BL/6J) YAC128 mouse uncovered by the operant delayed alternation task Journal of Neurology, Neurosurgery & Psychiatry. 81: A9.3-A10. DOI: 10.1136/jnnp.2010.222570.29  0.582
2009 Brooks SP, Dunnett SB. Tests to assess motor phenotype in mice: a user's guide. Nature Reviews. Neuroscience. 10: 519-29. PMID 19513088 DOI: 10.1038/nrn2652  0.543
2009 Brooks SP, Dunnett SB. Lesions of the premotor and supplementary motor areas fail to prevent implicit learning in the operant serial implicit learning task. Brain Research. 1284: 116-24. PMID 19501057 DOI: 10.1016/j.brainres.2009.05.081  0.49
2009 Brooks S, Fielding S, Döbrössy M, von Hörsten S, Dunnett S. Subtle but progressive cognitive deficits in the female tgHD hemizygote rat as demonstrated by operant SILT performance. Brain Research Bulletin. 79: 310-5. PMID 19480990 DOI: 10.1016/j.brainresbull.2009.03.003  0.523
2009 Trueman RC, Brooks SP, Jones L, Dunnett SB. Rule learning, visuospatial function and motor performance in the Hdh(Q92) knock-in mouse model of Huntington's disease. Behavioural Brain Research. 203: 215-22. PMID 19445966 DOI: 10.1016/j.bbr.2009.05.006  0.596
2008 Trueman RC, Brooks SP, Jones L, Dunnett SB. Time course of choice reaction time deficits in the Hdh(Q92) knock-in mouse model of Huntington's disease in the operant serial implicit learning task (SILT). Behavioural Brain Research. 189: 317-24. PMID 18367261 DOI: 10.1016/j.bbr.2008.01.020  0.571
2008 Hodges A, Hughes G, Brooks S, Elliston L, Holmans P, Dunnett SB, Jones L. Brain gene expression correlates with changes in behavior in the R6/1 mouse model of Huntington's disease. Genes, Brain, and Behavior. 7: 288-99. PMID 17696994 DOI: 10.1111/j.1601-183X.2007.00350.x  0.493
2007 Brooks SP, Trueman RC, Dunnett SB. Striatal lesions in the mouse disrupt acquisition and retention, but not implicit learning, in the SILT procedural motor learning task. Brain Research. 1185: 179-88. PMID 17964549 DOI: 10.1016/j.brainres.2007.09.017  0.461
2007 Trueman RC, Brooks SP, Jones L, Dunnett SB. The operant serial implicit learning task reveals early onset motor learning deficits in the Hdh knock-in mouse model of Huntington's disease. The European Journal of Neuroscience. 25: 551-8. PMID 17284197 DOI: 10.1111/j.1460-9568.2007.05307.x  0.566
2006 Brooks SP, Betteridge H, Trueman RC, Jones L, Dunnett SB. Selective extra-dimensional set shifting deficit in a knock-in mouse model of Huntington's disease. Brain Research Bulletin. 69: 452-7. PMID 16624677 DOI: 10.1016/j.brainresbull.2006.02.011  0.528
2005 Brooks SP, Pask T, Jones L, Dunnett SB. Behavioural profiles of inbred mouse strains used as transgenic backgrounds. II: cognitive tests. Genes, Brain, and Behavior. 4: 307-17. PMID 16011577 DOI: 10.1111/j.1601-183X.2004.00109.x  0.487
2005 Trueman RC, Brooks SP, Dunnett SB. Implicit learning in a serial choice visual discrimination task in the operant 9-hole box by intact and striatal lesioned mice. Behavioural Brain Research. 159: 313-22. PMID 15817194 DOI: 10.1016/j.bbr.2004.11.021  0.471
2004 Brooks SP, Pask T, Jones L, Dunnett SB. Behavioural profiles of inbred mouse strains used as transgenic backgrounds. I: motor tests. Genes, Brain, and Behavior. 3: 206-15. PMID 15248866 DOI: 10.1111/j.1601-183X.2004.00072.x  0.451
2004 Bensadoun JC, Brooks SP, Dunnett SB. Free operant and discrete trial performance of mice in the nine-hole box apparatus: validation using amphetamine and scopolamine. Psychopharmacology. 174: 396-405. PMID 14985934 DOI: 10.1007/s00213-003-1751-0  0.481
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