| Year |
Citation |
Score |
| 2024 |
Chakraborty D, Coslo DM, Murray IA, Vijay A, Patterson AD, Perdew GH. Immune cell-intrinsic Ah receptor facilitates the expression of antimicrobial REG3G in the small intestine. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 38: e23471. PMID 38358358 DOI: 10.1096/fj.202302319R |
0.302 |
|
| 2023 |
Patel D, Murray IA, Dong F, Annalora AJ, Gowda K, Coslo DM, Krzeminski J, Koo I, Hao F, Amin SG, Marcus CB, Patterson AD, Perdew GH. Induction of AHR Signaling in Response to the Indolimine Class of Microbial Stress Metabolites. Metabolites. 13. PMID 37755265 DOI: 10.3390/metabo13090985 |
0.439 |
|
| 2023 |
Saha K, Subramenium Ganapathy A, Wang A, Arumugam P, Michael Morris N, Harris L, Yochum G, Koltun W, Perdew GH, Nighot M, Ma T, Nighot P. Alpha-tocopherylquinone-mediated activation of the Aryl Hydrocarbon Receptor regulates the production of inflammation-inducing cytokines and ameliorates intestinal inflammation. Mucosal Immunology. PMID 37716509 DOI: 10.1016/j.mucimm.2023.09.003 |
0.309 |
|
| 2023 |
Morgan EW, Dong F, Annalora AJ, Murray IA, Wolfe T, Erickson R, Gowda K, Amin SG, Petersen KS, Kris-Etherton PM, Marcus CB, Walk ST, Patterson AD, Perdew GH. Contribution of Circulating Host and Microbial Tryptophan Metabolites Toward Ah Receptor Activation. International Journal of Tryptophan Research : Ijtr. 16: 11786469231182510. PMID 37441265 DOI: 10.1177/11786469231182510 |
0.341 |
|
| 2023 |
Dong F, Annalora AJ, Murray IA, Tian Y, Marcus CB, Patterson AD, Perdew GH. Endogenous Tryptophan-Derived Ah Receptor Ligands are Dissociated from CYP1A1/1B1-Dependent Negative-Feedback. International Journal of Tryptophan Research : Ijtr. 16: 11786469231182508. PMID 37434789 DOI: 10.1177/11786469231182508 |
0.343 |
|
| 2023 |
Dong F, Murray IA, Annalora A, Coslo DM, Desai D, Gowda K, Yang J, Wang D, Koo I, Hao F, Amin SG, Patterson AD, Marcus C, Perdew GH. Complex chemical signals dictate Ah receptor activation through the gut-lung axis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 37: e23010. PMID 37272852 DOI: 10.1096/fj.202300703R |
0.312 |
|
| 2023 |
Zhou X, Chakraborty D, Murray IA, Coslo D, Kehs Z, Vijay A, Ton C, Desai D, Amin SG, Patterson AD, Perdew GH. Aryl Hydrocarbon Receptor Activation Coordinates Mouse Small Intestinal Epithelial Cell Programming. Laboratory Investigation; a Journal of Technical Methods and Pathology. 103: 100012. PMID 37039146 DOI: 10.1016/j.labinv.2022.100012 |
0.401 |
|
| 2023 |
Dong F, Murray IA, Annalora A, Coslo D, Desai D, Gowda K, Yang J, Wang D, Koo I, Hao F, Amin SG, Patterson AD, Marcus C, Perdew GH. Complex chemical signals dictate Ah receptor activation through the gut-lung axis. Biorxiv : the Preprint Server For Biology. PMID 36865156 DOI: 10.1101/2023.02.22.529529 |
0.307 |
|
| 2023 |
Morgan EW, Dong F, Annalora A, Murray IA, Wolfe T, Erickson R, Gowda K, Amin SG, Petersen KS, Kris-Etherton PM, Marcus C, Walk ST, Patterson AD, Perdew GH. Contribution of circulating host and microbial tryptophan metabolites towards Ah receptor activation. Biorxiv : the Preprint Server For Biology. PMID 36747842 DOI: 10.1101/2023.01.26.525691 |
0.345 |
|
| 2022 |
Rikken G, Smith KJ, van den Brink NJM, Smits JPH, Gowda K, Alnemri A, Kuzu GE, Murray IA, Lin JM, Smits JGA, van Vlijmen-Willems IM, Amin SG, Perdew GH, van den Bogaard EH. Lead optimization of aryl hydrocarbon receptor ligands for treatment of inflammatory skin disorders. Biochemical Pharmacology. 115400. PMID 36574884 DOI: 10.1016/j.bcp.2022.115400 |
0.356 |
|
| 2021 |
Liu Q, Zhang L, Allman E, Hubbard TD, Murray IA, Hao F, Tian Y, Gui W, Nichols RG, Smith PB, Vijay AM, Perdew GH, Patterson AD. The Aryl Hydrocarbon Receptor Activates Ceramide Biosynthesis in Mice Contributing to Hepatic Lipogenesis. Toxicology. 152831. PMID 34097992 DOI: 10.1016/j.tox.2021.152831 |
0.338 |
|
| 2020 |
Dong F, Perdew GH. The aryl hydrocarbon receptor as a mediator of host-microbiota interplay. Gut Microbes. 12: 1859812. PMID 33382356 DOI: 10.1080/19490976.2020.1859812 |
0.3 |
|
| 2020 |
Murray IA, Perdew GH. How Ah Receptor Ligand Specificity Became Important in Understanding Its Physiological Function. International Journal of Molecular Sciences. 21. PMID 33348604 DOI: 10.3390/ijms21249614 |
0.383 |
|
| 2020 |
Dong F, Hao F, Murray IA, Smith PB, Koo I, Tindall AM, Kris-Etherton PM, Gowda K, Amin SG, Patterson AD, Perdew GH. Intestinal microbiota-derived tryptophan metabolites are predictive of Ah receptor activity. Gut Microbes. 12: 1-24. PMID 32783770 DOI: 10.1080/19490976.2020.1788899 |
0.417 |
|
| 2020 |
Dvořák Z, Kopp F, Costello CM, Kemp JS, Li H, Vrzalová A, Štěpánková M, Bartoňková I, Jiskrová E, Poulíková K, Vyhlídalová B, Nordstroem LU, Karunaratne CV, Ranhotra HS, Mun KS, ... ... Perdew GH, et al. Targeting the pregnane X receptor using microbial metabolite mimicry. Embo Molecular Medicine. e11621. PMID 32153125 DOI: 10.15252/Emmm.201911621 |
0.477 |
|
| 2019 |
Nichols RG, Zhang J, Cai J, Murray IA, Koo I, Smith PB, Perdew GH, Patterson AD. Metatranscriptomic Analysis of the Mouse Gut Microbiome Response to the Persistent Organic Pollutant 2,3,7,8-Tetrachlorodibenzofuran. Metabolites. 10. PMID 31861317 DOI: 10.3390/Metabo10010001 |
0.351 |
|
| 2019 |
Gourronc FA, Perdew GH, Robertson LW, Klingelhutz AJ. PCB126 blocks the thermogenic beiging response of adipocytes. Environmental Science and Pollution Research International. PMID 31721030 DOI: 10.1007/S11356-019-06663-0 |
0.367 |
|
| 2019 |
Muku GE, Kusnadi A, Kuzu G, Tanos R, Murray IA, Gowda K, Amin S, Perdew GH. Selective Ah receptor modulators attenuate NPC1L1-mediated cholesterol uptake through repression of SREBP-2 transcriptional activity. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 31417158 DOI: 10.1038/S41374-019-0306-X |
0.841 |
|
| 2019 |
Tian Y, Gui W, Smith PB, Koo I, Murray IA, Cantorna MT, Perdew GH, Patterson AD. Isolation and Identification of Aryl Hydrocarbon Receptor Modulators in White Button Mushrooms (Agaricus bisporus). Journal of Agricultural and Food Chemistry. PMID 31339733 DOI: 10.1021/Acs.Jafc.9B03212 |
0.406 |
|
| 2019 |
Muku GE, Blazanin N, Dong F, Smith PB, Thiboutot D, Gowda K, Amin S, Murray IA, Perdew GH. Selective Ah receptor ligands mediate enhanced SREBP1 proteolysis to restrict lipogenesis in sebocytes. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 31225620 DOI: 10.1093/Toxsci/Kfz140 |
0.563 |
|
| 2019 |
Hubbard TD, Liu Q, Murray IA, Dong F, Miller Iii C, Smith PB, Gowda K, Lin JM, Amin S, Patterson AD, Perdew GH. Microbiota metabolism promotes synthesis of the human Ah receptor agonist 2,8-dihydroxyquinoline. Journal of Proteome Research. PMID 30777439 DOI: 10.1021/Acs.Jproteome.8B00946 |
0.538 |
|
| 2019 |
Muku GE, Murray IA, Perdew GH. Activation of the Ah Receptor Modulates Gastrointestinal Homeostasis and the Intestinal Microbiome Current Pharmacology Reports. 5: 319-331. DOI: 10.1007/S40495-019-00197-2 |
0.504 |
|
| 2018 |
Muku GE, Murray IA, Espín JC, Perdew GH. Urolithin A Is a Dietary Microbiota-Derived Human Aryl Hydrocarbon Receptor Antagonist. Metabolites. 8. PMID 30501068 DOI: 10.3390/Metabo8040086 |
0.572 |
|
| 2018 |
Esser C, Lawrence BP, Sherr DH, Perdew GH, Puga A, Barouki R, Coumoul X. Old Receptor, New Tricks-The Ever-Expanding Universe of Aryl Hydrocarbon Receptor Functions. Report from the 4th AHR Meeting, 29⁻31 August 2018 in Paris, France. International Journal of Molecular Sciences. 19. PMID 30445691 DOI: 10.3390/Ijms19113603 |
0.395 |
|
| 2018 |
Belton KR, Tian Y, Zhang L, Anitha M, Smith PB, Perdew GH, Patterson AD. Metabolomics Reveals Aryl Hydrocarbon Receptor Activation Induces Liver and Mammary Gland Metabolic Dysfunction in Lactating Mice. Journal of Proteome Research. PMID 29521512 DOI: 10.1021/Acs.Jproteome.7B00709 |
0.415 |
|
| 2018 |
Smith KJ, Murray IA, Boyer JA, Perdew GH. Allelic variants of the aryl hydrocarbon receptor differentially influence UVB-mediated skin inflammatory responses in SKH1 mice. Toxicology. 394: 27-34. PMID 29197551 DOI: 10.1016/J.Tox.2017.11.020 |
0.407 |
|
| 2018 |
van den Bogaard E, Rikken G, Smits J, Perdew G. 1075 From old king coal to novel therapeutics for inflammatory skin diseases: The aryl hydrocarbon Receptor as a therapeutic target Journal of Investigative Dermatology. 138: S182. DOI: 10.1016/J.Jid.2018.03.1088 |
0.342 |
|
| 2017 |
Hubbard TD, Murray IA, Nichols RG, Cassel K, Podolsky M, Kuzu G, Tian Y, Smith P, Kennett MJ, Patterson AD, Perdew GH. Dietary Broccoli Impacts Microbial Community Structure and Attenuates Chemically Induced Colitis in Mice in an Ah receptor dependent manner. Journal of Functional Foods. 37: 685-698. PMID 29242716 DOI: 10.1016/J.Jff.2017.08.038 |
0.408 |
|
| 2017 |
Smith KJ, Boyer JA, Muku GE, Murray IA, Gowda K, Desai D, Amin SG, Glick AB, Perdew GH. Ah receptor activation potentiates neutrophil chemoattractant (C-X-C motif) ligand 5 expression in keratinocytes and skin. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28973351 DOI: 10.1093/Toxsci/Kfx160 |
0.529 |
|
| 2017 |
Murray IA, Perdew GH. Ligand activation of the Ah receptor contributes to gastrointestinal homeostasis. Current Opinion in Toxicology. 2: 15-23. PMID 28944314 DOI: 10.1016/J.Cotox.2017.01.003 |
0.504 |
|
| 2017 |
Organtini KL, Hubbard TD, Perdew GH, Dorman FL. Assessment of Ah receptor transcriptional activity mediated by halogenated dibenzo-p-dioxins and dibenzofurans (PXDD/Fs) in human and mouse cell systems. Journal of Environmental Science and Health. Part a, Toxic/Hazardous Substances & Environmental Engineering. 1-8. PMID 28922086 DOI: 10.1080/10934529.2017.1362290 |
0.464 |
|
| 2017 |
Muku GE, Lahoti TS, Murray IA, Podolsky MA, Smith KJ, Hubbard TD, Kuzu G, Gowda K, Amin SG, Perdew GH. Ligand-mediated cytoplasmic retention of the Ah receptor inhibits macrophage-mediated acute inflammatory responses. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 28892097 DOI: 10.1038/Labinvest.2017.92 |
0.818 |
|
| 2017 |
Moyer BJ, Rojas IY, Murray IA, Lee S, Hazlett HF, Perdew GH, Tomlinson CR. Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors activate the aryl hydrocarbon receptor. Toxicology and Applied Pharmacology. PMID 28336214 DOI: 10.1016/J.Taap.2017.03.012 |
0.427 |
|
| 2016 |
Koga T, Yao PL, Goudarzi M, Murray IA, Balandaram G, Gonzalez FJ, Perdew GH, Fornace AJ, Peters JM. Regulation of Cytochrome P450 2B10 (CYP2B10) Expression in Liver by Peroxisome Proliferator-Activated Receptor-β/δ Modulation of SP1 Promoter Occupancy. The Journal of Biological Chemistry. PMID 27765815 DOI: 10.1074/Jbc.M116.755447 |
0.45 |
|
| 2016 |
Murray IA, Nichols RG, Zhang L, Patterson AD, Perdew GH. Expression of the aryl hydrocarbon receptor contributes to the establishment of intestinal microbial community structure in mice. Scientific Reports. 6: 33969. PMID 27659481 DOI: 10.1038/Srep33969 |
0.388 |
|
| 2016 |
Hubbard TD, Murray IA, Bisson WH, Sullivan AP, Sebastian A, Perry GH, Jablonski NG, Perdew GH. Divergent Ah receptor ligand selectivity during hominin evolution. Molecular Biology and Evolution. PMID 27486223 DOI: 10.1093/Molbev/Msw143 |
0.458 |
|
| 2016 |
Balandaram G, Kramer LR, Kang BH, Murray IA, Perdew GH, Gonzalez FJ, Peters JM. Ligand activation of peroxisome proliferator-activated receptor-β/δ suppresses liver tumorigenesis in hepatitis B transgenic mice. Toxicology. PMID 27427494 DOI: 10.1016/J.Tox.2016.07.010 |
0.48 |
|
| 2016 |
Gutierrez MA, Davis SS, Rosko A, Nguyen SM, Mitchell KP, Mateen S, Neves J, Garcia TY, Mooney S, Perdew GH, Hubbard TD, Lamba DA, Ramanathan A. A novel AhR ligand, 2AI, protects the retina from environmental stress. Scientific Reports. 6: 29025. PMID 27364765 DOI: 10.1038/Srep29025 |
0.375 |
|
| 2016 |
Girer NG, Murray IA, Omiecinski CJ, Perdew GH. Hepatic Aryl Hydrocarbon Receptor Attenuates Fibroblast Growth Factor 21 Expression. The Journal of Biological Chemistry. PMID 27226639 DOI: 10.1074/Jbc.M116.715151 |
0.833 |
|
| 2015 |
Yang J, Hu S, Zhao L, Kaplan DH, Perdew GH, Xiong N. Selective programming of CCR10(+) innate lymphoid cells in skin-draining lymph nodes for cutaneous homeostatic regulation. Nature Immunology. PMID 26523865 DOI: 10.1038/Ni.3312 |
0.33 |
|
| 2015 |
Lahoti TS, Boyer JA, Kusnadi A, Muku GE, Murray IA, Perdew GH. Aryl Hydrocarbon Receptor Activation Synergistically Induces Lipopolysaccharide-Mediated Expression of Proinflammatory Chemokine (c-c motif) Ligand 20. Toxicological Sciences : An Official Journal of the Society of Toxicology. 148: 229-40. PMID 26259605 DOI: 10.1093/Toxsci/Kfv178 |
0.851 |
|
| 2015 |
Hubbard TD, Murray IA, Bisson WH, Lahoti TS, Gowda K, Amin SG, Patterson AD, Perdew GH. Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles. Scientific Reports. 5: 12689. PMID 26235394 DOI: 10.1038/Srep12689 |
0.84 |
|
| 2015 |
Hubbard TD, Murray IA, Perdew GH. Indole and Tryptophan Metabolism: Endogenous and Dietary Routes to Ah Receptor Activation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 1522-35. PMID 26041783 DOI: 10.1124/Dmd.115.064246 |
0.534 |
|
| 2015 |
Zhang L, Hatzakis E, Nichols RG, Hao R, Correll J, Smith PB, Chiaro CR, Perdew GH, Patterson AD. Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice. Environmental Science & Technology. 49: 8067-77. PMID 26023891 DOI: 10.1021/Acs.Est.5B01389 |
0.415 |
|
| 2015 |
Mohinta S, Kannan AK, Gowda K, Amin SG, Perdew GH, August A. Differential regulation of Th17 and T regulatory cell differentiation by aryl hydrocarbon receptor dependent xenobiotic response element dependent and independent pathways. Toxicological Sciences : An Official Journal of the Society of Toxicology. 145: 233-43. PMID 25716673 DOI: 10.1093/Toxsci/Kfv046 |
0.41 |
|
| 2015 |
van den Bogaard EH, Podolsky MA, Smits JP, Cui X, John C, Gowda K, Desai D, Amin SG, Schalkwijk J, Perdew GH, Glick AB. Genetic and pharmacological analysis identifies a physiological role for the AHR in epidermal differentiation. The Journal of Investigative Dermatology. 135: 1320-8. PMID 25602157 DOI: 10.1038/Jid.2015.6 |
0.438 |
|
| 2014 |
Murray IA, Patterson AD, Perdew GH. Aryl hydrocarbon receptor ligands in cancer: friend and foe. Nature Reviews. Cancer. 14: 801-14. PMID 25568920 DOI: 10.1038/Nrc3846 |
0.522 |
|
| 2014 |
Perkins A, Phillips JL, Kerkvliet NI, Tanguay RL, Perdew GH, Kolluri SK, Bisson WH. A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain. Biology. 3: 645-69. PMID 25329374 DOI: 10.3390/Biology3040645 |
0.491 |
|
| 2014 |
Borland MG, Krishnan P, Lee C, Albrecht PP, Shan W, Bility MT, Marcus CB, Lin JM, Amin S, Gonzalez FJ, Perdew GH, Peters JM. Modulation of aryl hydrocarbon receptor (AHR)-dependent signaling by peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in keratinocytes. Carcinogenesis. 35: 1602-12. PMID 24639079 DOI: 10.1093/Carcin/Bgu067 |
0.495 |
|
| 2014 |
Fang ZZ, Krausz KW, Nagaoka K, Tanaka N, Gowda K, Amin SG, Perdew GH, Gonzalez FJ. In vivo effects of the pure aryl hydrocarbon receptor antagonist GNF-351 after oral administration are limited to the gastrointestinal tract. British Journal of Pharmacology. 171: 1735-46. PMID 24417285 DOI: 10.1111/Bph.12576 |
0.453 |
|
| 2014 |
Lahoti TS, Hughes JM, Kusnadi A, John K, Zhu B, Murray IA, Gowda K, Peters JM, Amin SG, Perdew GH. Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis. The Journal of Pharmacology and Experimental Therapeutics. 348: 236-45. PMID 24309559 DOI: 10.1124/Jpet.113.209726 |
0.783 |
|
| 2014 |
Budinsky RA, Schrenk D, Simon T, Van den Berg M, Reichard JF, Silkworth JB, Aylward LL, Brix A, Gasiewicz T, Kaminski N, Perdew G, Starr TB, Walker NJ, Rowlands JC. Mode of action and dose-response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study. Critical Reviews in Toxicology. 44: 83-119. PMID 24245878 DOI: 10.3109/10408444.2013.835787 |
0.436 |
|
| 2014 |
John K, Lahoti TS, Wagner K, Hughes JM, Perdew GH. The Ah receptor regulates growth factor expression in head and neck squamous cell carcinoma cell lines. Molecular Carcinogenesis. 53: 765-76. PMID 23625689 DOI: 10.1002/Mc.22032 |
0.823 |
|
| 2013 |
Lahoti TS, John K, Hughes JM, Kusnadi A, Murray IA, Krishnegowda G, Amin S, Perdew GH. Aryl hydrocarbon receptor antagonism mitigates cytokine-mediated inflammatory signalling in primary human fibroblast-like synoviocytes. Annals of the Rheumatic Diseases. 72: 1708-16. PMID 23349129 DOI: 10.1136/Annrheumdis-2012-202639 |
0.807 |
|
| 2013 |
Labrecque MP, Takhar MK, Hollingshead BD, Prefontaine GG, Perdew GH, Beischlag TV. Effect of selective aryl hydrocarbon receptor modulators on estrogen-inducible transcription. Plos One. DOI: 10.1371/Journal.Pone.0029545.G004 |
0.79 |
|
| 2012 |
DiNatale BC, Smith K, John K, Krishnegowda G, Amin SG, Perdew GH. Ah receptor antagonism represses head and neck tumor cell aggressive phenotype. Molecular Cancer Research : McR. 10: 1369-79. PMID 22912337 DOI: 10.1158/1541-7786.Mcr-12-0216 |
0.817 |
|
| 2012 |
Tanos R, Murray IA, Smith PB, Patterson A, Perdew GH. Role of the Ah receptor in homeostatic control of fatty acid synthesis in the liver. Toxicological Sciences : An Official Journal of the Society of Toxicology. 129: 372-9. PMID 22696238 DOI: 10.1093/Toxsci/Kfs204 |
0.825 |
|
| 2012 |
Narayanan GA, Murray IA, Krishnegowda G, Amin S, Perdew GH. Selective aryl hydrocarbon receptor modulator-mediated repression of CD55 expression induced by cytokine exposure. The Journal of Pharmacology and Experimental Therapeutics. 342: 345-55. PMID 22553215 DOI: 10.1124/Jpet.112.193482 |
0.449 |
|
| 2012 |
Labrecque MP, Takhar MK, Hollingshead BD, Prefontaine GG, Perdew GH, Beischlag TV. Distinct roles for aryl hydrocarbon receptor nuclear translocator and ah receptor in estrogen-mediated signaling in human cancer cell lines. Plos One. 7: e29545. PMID 22235307 DOI: 10.1371/Journal.Pone.0029545 |
0.811 |
|
| 2012 |
Tanos R, Patel RD, Murray IA, Smith PB, Patterson AD, Perdew GH. Aryl hydrocarbon receptor regulates the cholesterol biosynthetic pathway in a dioxin response element-independent manner. Hepatology (Baltimore, Md.). 55: 1994-2004. PMID 22234961 DOI: 10.1002/Hep.25571 |
0.842 |
|
| 2011 |
Smith KJ, Murray IA, Tanos R, Tellew J, Boitano AE, Bisson WH, Kolluri SK, Cooke MP, Perdew GH. Identification of a high-affinity ligand that exhibits complete aryl hydrocarbon receptor antagonism. The Journal of Pharmacology and Experimental Therapeutics. 338: 318-27. PMID 21493753 DOI: 10.1124/Jpet.110.178392 |
0.845 |
|
| 2011 |
Murray IA, Flaveny CA, Chiaro CR, Sharma AK, Tanos RS, Schroeder JC, Amin SG, Bisson WH, Kolluri SK, Perdew GH. Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3',4'-dimethoxy-α-naphthoflavone. Molecular Pharmacology. 79: 508-19. PMID 21127131 DOI: 10.1124/Mol.110.069369 |
0.845 |
|
| 2011 |
DiNatale BC, Schroeder JC, Perdew GH. Ah receptor antagonism inhibits constitutive and cytokine inducible IL6 production in head and neck tumor cell lines. Molecular Carcinogenesis. 50: 173-83. PMID 21104991 DOI: 10.1002/Mc.20702 |
0.819 |
|
| 2011 |
Omiecinski CJ, Vanden Heuvel JP, Perdew GH, Peters JM. Xenobiotic metabolism, disposition, and regulation by receptors: from biochemical phenomenon to predictors of major toxicities. Toxicological Sciences : An Official Journal of the Society of Toxicology. 120: S49-75. PMID 21059794 DOI: 10.1093/Toxsci/Kfq338 |
0.387 |
|
| 2010 |
Perdew GH, Hollingshead BD, Dinatale BC, Morales JL, Labrecque MP, Takhar MK, Tam KJ, Beischlag TV. Estrogen receptor expression is required for low-dose resveratrol-mediated repression of aryl hydrocarbon receptor activity. The Journal of Pharmacology and Experimental Therapeutics. 335: 273-83. PMID 20716622 DOI: 10.1124/Jpet.110.170654 |
0.826 |
|
| 2010 |
Boitano AE, Wang J, Romeo R, Bouchez LC, Parker AE, Sutton SE, Walker JR, Flaveny CA, Perdew GH, Denison MS, Schultz PG, Cooke MP. Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science (New York, N.Y.). 329: 1345-8. PMID 20688981 DOI: 10.1126/Science.1191536 |
0.734 |
|
| 2010 |
Palkar PS, Borland MG, Naruhn S, Ferry CH, Lee C, Sk UH, Sharma AK, Amin S, Murray IA, Anderson CR, Perdew GH, Gonzalez FJ, Müller R, Peters JM. Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-beta/delta antagonist GSK3787. Molecular Pharmacology. 78: 419-30. PMID 20516370 DOI: 10.1124/Mol.110.065508 |
0.516 |
|
| 2010 |
DiNatale BC, Schroeder JC, Francey LJ, Kusnadi A, Perdew GH. Mechanistic insights into the events that lead to synergistic induction of interleukin 6 transcription upon activation of the aryl hydrocarbon receptor and inflammatory signaling. The Journal of Biological Chemistry. 285: 24388-97. PMID 20511231 DOI: 10.1074/Jbc.M110.118570 |
0.829 |
|
| 2010 |
Murray IA, Krishnegowda G, DiNatale BC, Flaveny C, Chiaro C, Lin JM, Sharma AK, Amin S, Perdew GH. Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties. Chemical Research in Toxicology. 23: 955-66. PMID 20423157 DOI: 10.1021/Tx100045H |
0.85 |
|
| 2010 |
DiNatale BC, Perdew GH. Protein function analysis: rapid, cell-based siRNA-mediated ablation of endogenous expression with simultaneous ectopic replacement. Cytotechnology. 62: 495-503. PMID 20390449 DOI: 10.1007/S10616-010-9270-4 |
0.794 |
|
| 2010 |
DiNatale BC, Murray IA, Schroeder JC, Flaveny CA, Lahoti TS, Laurenzana EM, Omiecinski CJ, Perdew GH. Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling. Toxicological Sciences : An Official Journal of the Society of Toxicology. 115: 89-97. PMID 20106948 DOI: 10.1093/Toxsci/Kfq024 |
0.82 |
|
| 2010 |
Flaveny CA, Murray IA, Perdew GH. Differential gene regulation by the human and mouse aryl hydrocarbon receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. 114: 217-25. PMID 20044593 DOI: 10.1093/Toxsci/Kfp308 |
0.788 |
|
| 2010 |
Schroeder JC, Dinatale BC, Murray IA, Flaveny CA, Liu Q, Laurenzana EM, Lin JM, Strom SC, Omiecinski CJ, Amin S, Perdew GH. The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor. Biochemistry. 49: 393-400. PMID 20000589 DOI: 10.1021/Bi901786X |
0.842 |
|
| 2010 |
Murray IA, Morales JL, Flaveny CA, Dinatale BC, Chiaro C, Gowdahalli K, Amin S, Perdew GH. Evidence for ligand-mediated selective modulation of aryl hydrocarbon receptor activity. Molecular Pharmacology. 77: 247-54. PMID 19903824 DOI: 10.1124/Mol.109.061788 |
0.838 |
|
| 2010 |
Murray IA, Flaveny CA, DiNatale BC, Chairo CR, Schroeder JC, Kusnadi A, Perdew GH. Antagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimethoxyflavone. The Journal of Pharmacology and Experimental Therapeutics. 332: 135-44. PMID 19828881 DOI: 10.1124/Jpet.109.158261 |
0.824 |
|
| 2010 |
DiNatale B, Perdew GH. Abstract 1226: The AH receptor plays a key role in mediating IL6 production in head and neck tumor cell lines Cancer Research. 70: 1226-1226. DOI: 10.1158/1538-7445.Am10-1226 |
0.825 |
|
| 2009 |
Flaveny CA, Perdew GH. Transgenic Humanized AHR Mouse Reveals Differences between Human and Mouse AHR Ligand Selectivity. Molecular and Cellular Pharmacology. 1: 119-123. PMID 20419055 DOI: 10.4255/Mcpharmacol.09.15 |
0.791 |
|
| 2009 |
Flaveny C, Perdew GH, Miller CA. The Aryl-hydrocarbon receptor does not require the p23 co-chaperone for ligand binding and target gene expression in vivo. Toxicology Letters. 189: 57-62. PMID 19447165 DOI: 10.1016/J.Toxlet.2009.05.002 |
0.784 |
|
| 2009 |
Patel RD, Murray IA, Flaveny CA, Kusnadi A, Perdew GH. Ah receptor represses acute-phase response gene expression without binding to its cognate response element. Laboratory Investigation; a Journal of Technical Methods and Pathology. 89: 695-707. PMID 19333233 DOI: 10.1038/Labinvest.2009.24 |
0.8 |
|
| 2009 |
Flaveny CA, Murray IA, Chiaro CR, Perdew GH. Ligand selectivity and gene regulation by the human aryl hydrocarbon receptor in transgenic mice. Molecular Pharmacology. 75: 1412-20. PMID 19299563 DOI: 10.1124/Mol.109.054825 |
0.785 |
|
| 2008 |
Perdew GH. Ah receptor binding to its cognate response element is required for dioxin-mediated toxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 106: 301-3. PMID 18930947 DOI: 10.1093/Toxsci/Kfn220 |
0.513 |
|
| 2008 |
Chiaro CR, Patel RD, Perdew GH. 12(R)-Hydroxy-5(Z),8(Z),10(E),14(Z)-eicosatetraenoic acid [12(R)-HETE], an arachidonic acid derivative, is an activator of the aryl hydrocarbon receptor. Molecular Pharmacology. 74: 1649-56. PMID 18779363 DOI: 10.1124/Mol.108.049379 |
0.451 |
|
| 2008 |
Shan W, Palkar PS, Murray IA, McDevitt EI, Kennett MJ, Kang BH, Isom HC, Perdew GH, Gonzalez FJ, Peters JM. Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) attenuates carbon tetrachloride hepatotoxicity by downregulating proinflammatory gene expression. Toxicological Sciences : An Official Journal of the Society of Toxicology. 105: 418-28. PMID 18622026 DOI: 10.1093/Toxsci/Kfn142 |
0.479 |
|
| 2008 |
Chiaro CR, Morales JL, Prabhu KS, Perdew GH. Leukotriene A4 metabolites are endogenous ligands for the Ah receptor. Biochemistry. 47: 8445-55. PMID 18616291 DOI: 10.1021/Bi800712F |
0.695 |
|
| 2008 |
Beischlag TV, Luis Morales J, Hollingshead BD, Perdew GH. The aryl hydrocarbon receptor complex and the control of gene expression. Critical Reviews in Eukaryotic Gene Expression. 18: 207-50. PMID 18540824 DOI: 10.1615/Critreveukargeneexpr.V18.I3.20 |
0.827 |
|
| 2008 |
Hollingshead BD, Beischlag TV, Dinatale BC, Ramadoss P, Perdew GH. Inflammatory signaling and aryl hydrocarbon receptor mediate synergistic induction of interleukin 6 in MCF-7 cells. Cancer Research. 68: 3609-17. PMID 18483242 DOI: 10.1158/0008-5472.Can-07-6168 |
0.784 |
|
| 2008 |
Girroir EE, Hollingshead HE, He P, Zhu B, Perdew GH, Peters JM. Quantitative expression patterns of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) protein in mice. Biochemical and Biophysical Research Communications. 371: 456-61. PMID 18442472 DOI: 10.1016/J.Bbrc.2008.04.086 |
0.365 |
|
| 2008 |
Flaveny C, Reen RK, Kusnadi A, Perdew GH. The mouse and human Ah receptor differ in recognition of LXXLL motifs. Archives of Biochemistry and Biophysics. 471: 215-23. PMID 18242161 DOI: 10.1016/J.Abb.2008.01.014 |
0.756 |
|
| 2008 |
Morales JL, Krzeminski J, Amin S, Perdew GH. Characterization of the antiallergic drugs 3-[2-(2-phenylethyl) benzoimidazole-4-yl]-3-hydroxypropanoic acid and ethyl 3-hydroxy-3-[2-(2-phenylethyl)benzoimidazol-4-yl]propanoate as full aryl hydrocarbon receptor agonists. Chemical Research in Toxicology. 21: 472-82. PMID 18179178 DOI: 10.1021/Tx700350V |
0.622 |
|
| 2008 |
Murray IA, Perdew GH. Omeprazole stimulates the induction of human insulin-like growth factor binding protein-1 through aryl hydrocarbon receptor activation. The Journal of Pharmacology and Experimental Therapeutics. 324: 1102-10. PMID 18055878 DOI: 10.1124/Jpet.107.132241 |
0.508 |
|
| 2007 |
Chiaro CR, Patel RD, Marcus CB, Perdew GH. Evidence for an aryl hydrocarbon receptor-mediated cytochrome p450 autoregulatory pathway. Molecular Pharmacology. 72: 1369-79. PMID 17720764 DOI: 10.1124/Mol.107.038968 |
0.489 |
|
| 2007 |
Sun YW, Herzog CR, Krzeminski J, Amin S, Perdew G, El-Bayoumy K. Effects of the environmental mammary carcinogen 6-nitrochrysene on p53 and p21(Cip1) protein expression and cell cycle regulation in MCF-7 and MCF-10A cells. Chemico-Biological Interactions. 170: 31-9. PMID 17678638 DOI: 10.1016/J.Cbi.2007.06.039 |
0.338 |
|
| 2007 |
Patel RD, Hollingshead BD, Omiecinski CJ, Perdew GH. Aryl-hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver. Hepatology (Baltimore, Md.). 46: 209-18. PMID 17596880 DOI: 10.1002/Hep.21671 |
0.818 |
|
| 2007 |
Morales JL, Perdew GH. Carboxyl terminus of hsc70-interacting protein (CHIP) can remodel mature aryl hydrocarbon receptor (AhR) complexes and mediate ubiquitination of both the AhR and the 90 kDa heat-shock protein (hsp90) in vitro. Biochemistry. 46: 610-21. PMID 17209571 DOI: 10.1021/Bi062165B |
0.646 |
|
| 2006 |
Hollingshead BD, Patel RD, Perdew GH. Endogenous hepatic expression of the hepatitis B virus X-associated protein 2 is adequate for maximal association with aryl hydrocarbon receptor-90-kDa heat shock protein complexes. Molecular Pharmacology. 70: 2096-107. PMID 16988012 DOI: 10.1124/Mol.106.029215 |
0.818 |
|
| 2006 |
Chen YH, Beischlag TV, Kim JH, Perdew GH, Stallcup MR. Role of GAC63 in transcriptional activation mediated by the aryl hydrocarbon receptor. The Journal of Biological Chemistry. 281: 12242-7. PMID 16513642 DOI: 10.1074/Jbc.M512537200 |
0.54 |
|
| 2006 |
Patel RD, Kim DJ, Peters JM, Perdew GH. The aryl hydrocarbon receptor directly regulates expression of the potent mitogen epiregulin. Toxicological Sciences : An Official Journal of the Society of Toxicology. 89: 75-82. PMID 16192470 DOI: 10.1093/Toxsci/Kfi344 |
0.51 |
|
| 2005 |
Ramadoss P, Marcus C, Perdew GH. Role of the aryl hydrocarbon receptor in drug metabolism. Expert Opinion On Drug Metabolism & Toxicology. 1: 9-21. PMID 16922649 DOI: 10.1517/17425255.1.1.9 |
0.765 |
|
| 2005 |
Murray IA, Reen RK, Leathery N, Ramadoss P, Bonati L, Gonzalez FJ, Peters JM, Perdew GH. Evidence that ligand binding is a key determinant of Ah receptor-mediated transcriptional activity. Archives of Biochemistry and Biophysics. 442: 59-71. PMID 16137638 DOI: 10.1016/J.Abb.2005.07.014 |
0.799 |
|
| 2005 |
Ramadoss P, Perdew GH. The transactivation domain of the Ah receptor is a key determinant of cellular localization and ligand-independent nucleocytoplasmic shuttling properties. Biochemistry. 44: 11148-59. PMID 16101299 DOI: 10.1021/Bi050948B |
0.788 |
|
| 2005 |
Gray JP, Burns KA, Leas TL, Perdew GH, Vanden Heuvel JP. Regulation of peroxisome proliferator-activated receptor alpha by protein kinase C. Biochemistry. 44: 10313-21. PMID 16042408 DOI: 10.1021/Bi050721G |
0.441 |
|
| 2005 |
Beischlag TV, Perdew GH. ER alpha-AHR-ARNT protein-protein interactions mediate estradiol-dependent transrepression of dioxin-inducible gene transcription. The Journal of Biological Chemistry. 280: 21607-11. PMID 15837795 DOI: 10.1074/Jbc.C500090200 |
0.471 |
|
| 2005 |
Kim DJ, Murray IA, Burns AM, Gonzalez FJ, Perdew GH, Peters JM. Peroxisome proliferator-activated receptor-beta/delta inhibits epidermal cell proliferation by down-regulation of kinase activity. The Journal of Biological Chemistry. 280: 9519-27. PMID 15632134 DOI: 10.1074/Jbc.M413808200 |
0.386 |
|
| 2004 |
Hollingshead BD, Petrulis JR, Perdew GH. The aryl hydrocarbon (Ah) receptor transcriptional regulator hepatitis B virus X-associated protein 2 antagonizes p23 binding to Ah receptor-Hsp90 complexes and is dispensable for receptor function. The Journal of Biological Chemistry. 279: 45652-61. PMID 15322122 DOI: 10.1074/Jbc.M407840200 |
0.821 |
|
| 2004 |
Ramadoss P, Perdew GH. Use of 2-azido-3-[125I]iodo-7,8-dibromodibenzo-p-dioxin as a probe to determine the relative ligand affinity of human versus mouse aryl hydrocarbon receptor in cultured cells. Molecular Pharmacology. 66: 129-36. PMID 15213304 DOI: 10.1124/Mol.66.1.129 |
0.779 |
|
| 2004 |
Ramadoss P, Petrulis JR, Hollingshead BD, Kusnadi A, Perdew GH. Divergent roles of hepatitis B virus X-associated protein 2 (XAP2) in human versus mouse Ah receptor complexes. Biochemistry. 43: 700-9. PMID 14730974 DOI: 10.1021/Bi035827V |
0.821 |
|
| 2003 |
Sumanasekera WK, Tien ES, Davis JW, Turpey R, Perdew GH, Vanden Heuvel JP. Heat shock protein-90 (Hsp90) acts as a repressor of peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARbeta activity. Biochemistry. 42: 10726-35. PMID 12962497 DOI: 10.1021/Bi0347353 |
0.827 |
|
| 2003 |
Sumanasekera WK, Tien ES, Turpey R, Vanden Heuvel JP, Perdew GH. Evidence that peroxisome proliferator-activated receptor alpha is complexed with the 90-kDa heat shock protein and the hepatitis virus B X-associated protein 2. The Journal of Biological Chemistry. 278: 4467-73. PMID 12482853 DOI: 10.1074/Jbc.M211261200 |
0.837 |
|
| 2003 |
Petrulis JR, Kusnadi A, Ramadoss P, Hollingshead B, Perdew GH. The hsp90 Co-chaperone XAP2 alters importin beta recognition of the bipartite nuclear localization signal of the Ah receptor and represses transcriptional activity. The Journal of Biological Chemistry. 278: 2677-85. PMID 12431985 DOI: 10.1074/Jbc.M209331200 |
0.835 |
|
| 2002 |
Reen RK, Cadwallader A, Perdew GH. The subdomains of the transactivation domain of the aryl hydrocarbon receptor (AhR) inhibit AhR and estrogen receptor transcriptional activity. Archives of Biochemistry and Biophysics. 408: 93-102. PMID 12485607 DOI: 10.1016/S0003-9861(02)00518-0 |
0.55 |
|
| 2002 |
Carlson DB, Perdew GH. A dynamic role for the Ah receptor in cell signaling? Insights from a diverse group of Ah receptor interacting proteins. Journal of Biochemical and Molecular Toxicology. 16: 317-25. PMID 12481307 DOI: 10.1002/Jbt.10051 |
0.505 |
|
| 2002 |
Swanson HI, Whitelaw ML, Petrulis JR, Perdew GH. Use of [125I]4'-iodoflavone as a tool to characterize ligand-dependent differences in Ah receptor behavior. Journal of Biochemical and Molecular Toxicology. 16: 298-310. PMID 12481305 DOI: 10.1002/Jbt.10053 |
0.501 |
|
| 2002 |
Dull AB, Carlson DB, Petrulis JR, Perdew GH. Characterization of the phosphorylation status of the hepatitis B virus X-associated protein 2. Archives of Biochemistry and Biophysics. 406: 209-21. PMID 12361709 DOI: 10.1016/S0003-9861(02)00444-7 |
0.327 |
|
| 2002 |
Petrulis JR, Perdew GH. The role of chaperone proteins in the aryl hydrocarbon receptor core complex. Chemico-Biological Interactions. 141: 25-40. PMID 12213383 DOI: 10.1016/S0009-2797(02)00064-9 |
0.5 |
|
| 2002 |
Levine SL, Perdew GH. Okadaic acid increases ARNT homodimer transactivation potential Cell Biology and Toxicology. 18: 109-120. PMID 12046689 DOI: 10.1023/A:1015332217714 |
0.415 |
|
| 2001 |
Petrulis JR, Perdew GH. Monitoring nuclear import with GFP-variant fusion proteins in digitonin-permeabilized cells Biotechniques. 31: 772-775. PMID 11680706 DOI: 10.2144/01314St02 |
0.3 |
|
| 2001 |
Kumar MB, Ramadoss P, Reen RK, Vanden Heuvel JP, Perdew GH. The Q-rich subdomain of the human Ah receptor transactivation domain is required for dioxin-mediated transcriptional activity. The Journal of Biological Chemistry. 276: 42302-10. PMID 11551916 DOI: 10.1074/Jbc.M104798200 |
0.817 |
|
| 2001 |
Levine SL, Perdew GH. Aryl hydrocarbon receptor (AHR)/AhR nuclear translocator (ARNT) activity is unaltered by phosphorylation of a periodicity/ARNT/single-minded (PAS)-region serine residue Molecular Pharmacology. 59: 557-566. PMID 11179451 DOI: 10.1124/Mol.59.3.557 |
0.394 |
|
| 2000 |
Levine SL, Petrulis JR, Dubil A, Perdew GH. A tetratricopeptide repeat half-site in the aryl hydrocarbon receptor is important for DNA binding and trans-activation potential Molecular Pharmacology. 58: 1517-1524. PMID 11093792 DOI: 10.1124/Mol.58.6.1517 |
0.459 |
|
| 2000 |
Meyer BK, Petrulis JR, Perdew GH. Aryl hydrocarbon (Ah) receptor levels are selectively modulated by hsp90-associated immunophilin homolog XAP2 Cell Stress and Chaperones. 5: 243-254. PMID 11005382 DOI: 10.1379/1466-1268(2000)005<0243:Aharla>2.0.Co;2 |
0.48 |
|
| 2000 |
Petrulis JR, Hord NG, Perdew GH. Subcellular localization of the aryl hydrocarbon receptor is modulated by the immunophilin homolog hepatitis B virus X-associated protein 2 Journal of Biological Chemistry. 275: 37448-37453. PMID 10986286 DOI: 10.1074/Jbc.M006873200 |
0.49 |
|
| 1999 |
Kumar MB, Perdew GH. Nuclear receptor coactivator SRC-1 interacts with the Q-rich subdomain of the AhR and modulates its transactivation potential. Gene Expression. 8: 273-86. PMID 10947077 |
0.644 |
|
| 1999 |
Long WP, Perdew GH. Lack of an absolute requirement for the native aryl hydrocarbon receptor (AhR) and AhR nuclear translocator transactivation domains in protein kinase C-mediated modulation of the AhR pathway. Archives of Biochemistry and Biophysics. 371: 246-59. PMID 10545212 DOI: 10.1006/Abbi.1999.1452 |
0.416 |
|
| 1999 |
Kumar MB, Tarpey RW, Perdew GH. Differential recruitment of coactivator RIP140 by Ah and estrogen receptors. Absence of a role for LXXLL motifs. The Journal of Biological Chemistry. 274: 22155-64. PMID 10428779 DOI: 10.1074/Jbc.274.32.22155 |
0.718 |
|
| 1999 |
Meyer BK, Perdew GH. Characterization of the AhR-hsp90-XAP2 core complex and the role of the immunophilin-related protein XAP2 in AhR stabilization Biochemistry. 38: 8907-8917. PMID 10413464 DOI: 10.1021/Bi982223W |
0.449 |
|
| 1999 |
Long WP, Chen X, Perdew GH. Protein kinase C modulates aryl hydrocarbon receptor nuclear translocator protein-mediated transactivation potential in a dimer context Journal of Biological Chemistry. 274: 12391-12400. PMID 10212212 DOI: 10.1074/Jbc.274.18.12391 |
0.451 |
|
| 1998 |
Abbott BD, Probst MR, Perdew GH, Buckalew AR. AH receptor, ARNT, glucocorticoid receptor, EGF receptor, EGF, TGFα, TGFβ1, TGFβ2, and TGFβ3 expression in human embryonic palate, and effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) Teratology. 58: 30-43. PMID 9787404 DOI: 10.1002/(Sici)1096-9926(199808)58:2<30::Aid-Tera4>3.0.Co;2-4 |
0.458 |
|
| 1998 |
Brunt SA, Perdew GH, Toft DO, Silver JC. Hsp90-containing multiprotein complexes in the eukaryotic microbe Achlya Cell Stress and Chaperones. 3: 44-56. PMID 9585181 DOI: 10.1379/1466-1268(1998)003<0044:Hcmcit>2.3.Co;2 |
0.329 |
|
| 1998 |
Long WP, Pray-Grant M, Tsai JC, Perdew GH. Protein kinase C activity is required for aryl hydrocarbon receptor pathway-mediated signal transduction Molecular Pharmacology. 53: 691-700. PMID 9547360 DOI: 10.1124/Mol.53.4.691 |
0.489 |
|
| 1998 |
Meyer BK, Pray-Grant MG, Vanden Heuvel JP, Perdew GH. Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity Molecular and Cellular Biology. 18: 978-988. PMID 9447995 DOI: 10.1128/Mcb.18.2.978 |
0.476 |
|
| 1997 |
Chen HS, Singh SS, Perdew GH. The Ah receptor is a sensitive target of geldanamycin-induced protein turnover Archives of Biochemistry and Biophysics. 348: 190-198. PMID 9390191 DOI: 10.1006/Abbi.1997.0398 |
0.357 |
|
| 1997 |
Tsai JC, Perdew GH. Ah receptor nuclear translocator protein heterogeneity is altered after heterodimerization with the Ah receptor Biochemistry. 36: 9066-9072. PMID 9220996 DOI: 10.1021/Bi970891W |
0.441 |
|
| 1997 |
Perdew GH, Wiegand H, Vanden Heuvel JP, Mitchell C, Singh SS. A 50 kilodalton protein associated with raf and pp60(v-src) protein kinases is a mammalian homolog of the cell cycle control protein cdc37 Biochemistry. 36: 3600-3607. PMID 9132011 DOI: 10.1021/Bi9612529 |
0.331 |
|
| 1997 |
Hogenesch JB, Chan WK, Jackiw VH, Brown RC, Gu YZ, Pray-Grant M, Perdew GH, Bradfield CA. Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway. The Journal of Biological Chemistry. 272: 8581-93. PMID 9079689 DOI: 10.1074/jbc.272.13.8581 |
0.339 |
|
| 1996 |
Perdew GH, Bradfield CA. Mapping the 90 kDa heat shock protein binding region of the Ah receptor. Biochemistry and Molecular Biology International. 39: 589-93. PMID 8828811 DOI: 10.1080/15216549600201651 |
0.402 |
|
| 1996 |
Owens-Grillo JK, Czar MJ, Hutchison KA, Hoffmann K, Perdew GH, Pratt WB. A model of protein targeting mediated by immunophilins and other proteins that bind to hsp90 via tetratricopeptide repeat domains. The Journal of Biological Chemistry. 271: 13468-75. PMID 8662874 DOI: 10.1074/Jbc.271.23.13468 |
0.391 |
|
| 1996 |
Singh SS, Hord NG, Perdew GH. Characterization of the activated form of the aryl hydrocarbon receptor in the nucleus of HeLa cells in the absence of exogenous ligand Archives of Biochemistry and Biophysics. 329: 47-55. PMID 8619634 DOI: 10.1006/Abbi.1996.0190 |
0.515 |
|
| 1995 |
Xiaohong Wang, Thomsen JS, Santostefano M, Rosengren R, Safe S, Perdew GH. Comparative properties of the nuclear aryl hydrocarbon (Ah) receptor complex from several human cell lines European Journal of Pharmacology: Environmental Toxicology And. 293: 191-205. PMID 8666036 DOI: 10.1016/0926-6917(95)00017-8 |
0.434 |
|
| 1995 |
Abbott BD, Birnbaum LS, Perdew GH. Developmental expression of two members of a new class of transcription factors: I. Expression of aryl hydrocarbon receptor in the C57BL/6N mouse embryo Developmental Dynamics. 204: 133-143. PMID 8589437 DOI: 10.1002/Aja.1002040204 |
0.451 |
|
| 1995 |
Perdew GH, Abbott B, Stanker LH. Production and characterization of monoclonal antibodies directed against the Ah receptor Hybridoma. 14: 279-283. PMID 7590792 DOI: 10.1089/Hyb.1995.14.279 |
0.354 |
|
| 1995 |
Perdew GH, Hollenback CE. Evidence for two functionally distinct forms of the human Ah receptor Journal of Biochemical Toxicology. 10: 95-102. PMID 7562958 DOI: 10.1002/Jbt.2570100206 |
0.337 |
|
| 1994 |
Abbott BD, Perdew GH, Birnbaum LS. Ah receptor in embryonic mouse palate and effects of TCDD on receptor expression Toxicology and Applied Pharmacology. 126: 16-25. PMID 8184424 DOI: 10.1006/Taap.1994.1085 |
0.488 |
|
| 1994 |
Abbott BD, Perdew GH, Buckalew AR, Birnbaum LS. Interactive regulation of Ah and glucocorticoid receptors in the synergistic induction of cleft palate by 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone Toxicology and Applied Pharmacology. 128: 138-150. PMID 8079347 DOI: 10.1006/Taap.1994.1191 |
0.476 |
|
| 1994 |
Abbott BD, Probst MR, Perdew GH. Immunohistochemical double-staining for Ah receptor and ARNT in human embryonic palatal shelves Teratology. 50: 361-366. PMID 7716743 DOI: 10.1002/Tera.1420500507 |
0.54 |
|
| 1994 |
Hord NG, Perdew GH. Physicochemical and immunocytochemical analysis of the aryl hydrocarbon receptor nuclear translocator: Characterization of two monoclonal antibodies to the aryl hydrocarbon receptor nuclear translocator Molecular Pharmacology. 46: 618-626. PMID 7526149 |
0.329 |
|
| 1993 |
Singh SS, Perdew GH. Alterations in the Ah receptor level after staurosporine treatment Archives of Biochemistry and Biophysics. 305: 170-175. PMID 8393644 DOI: 10.1006/Abbi.1993.1407 |
0.523 |
|
| 1993 |
Swanson HI, Perdew GH. Half-life of aryl hydrocarbon receptor in Hepa 1 cells: Evidence for ligand-dependent alterations in cytosolic receptor levels Archives of Biochemistry and Biophysics. 302: 167-174. PMID 8385898 DOI: 10.1006/Abbi.1993.1195 |
0.396 |
|
| 1992 |
Perdew GH. Chemical cross-linking of the cytosolic and nuclear forms of the Ah receptor in hepatoma cell line 1c1c7 Biochemical and Biophysical Research Communications. 182: 55-62. PMID 1310021 DOI: 10.1016/S0006-291X(05)80111-1 |
0.351 |
|
| 1991 |
Perdew GH, Babbs CF. Production of Ah Receptor Ligands in Rat Fecal Suspensions Containing Tryptophan or Indole-3-Carbinol Nutrition and Cancer. 16: 209-218. PMID 1663613 DOI: 10.1080/01635589109514159 |
0.458 |
|
| 1991 |
Perdew GH. Comparison of the nuclear and cytosolic forms of the Ah receptor from Hepa 1c1c7 cells: Charge heterogeneity and ATP binding properties Archives of Biochemistry and Biophysics. 291: 284-290. PMID 1659322 DOI: 10.1016/0003-9861(91)90136-7 |
0.354 |
|
| 1991 |
Swanson HI, Perdew GH. Detection of the Ah receptor in rainbow trout: Use of 2-azido-3-[125I]iodo-7,8-dibromodibenzo-P-dioxmin in cell culture Toxicology Letters. 58: 85-95. PMID 1654604 DOI: 10.1016/0378-4274(91)90194-B |
0.469 |
|
| 1990 |
Dalman FC, Koenig RJ, Perdew GH, Massa E, Pratt WB. In contrast to the glucocorticoid receptor, the thyroid hormone receptor is translated in the DNA binding state and is not associated with hsp90 Journal of Biological Chemistry. 265: 3615-3618. PMID 2303466 |
0.331 |
|
| 1990 |
Perdew GH, Hollenback CE. Analysis of photoaffinity-labeled aryl hydrocarbon receptor heterogeneity by two-dimensional gel electrophoresis Biochemistry. 29: 6210-6214. PMID 2169866 DOI: 10.1021/Bi00478A014 |
0.316 |
|
| 1989 |
Dalman FC, Bresnick EH, Patel PD, Perdew GH, Watson SJ, Pratt WB. Direct evidence that the glucocorticoid receptor binds to hsp90 at or near the termination of receptor translation in vitro. The Journal of Biological Chemistry. 264: 19815-21. PMID 2584195 |
0.352 |
|
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