Madeline A. Lancaster, Ph.D. - Publications

Affiliations: 
2004-2010 Biomedical Sciences University of California, San Diego, La Jolla, CA 
 2010-2015 Institute of Molecular Biotechnology (IMBA) 
 2015- Cell Biology MRC Laboratory of Molecular Biology, Cambridge, England, United Kingdom 

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Benito-Kwiecinski S, Giandomenico SL, Sutcliffe M, Riis ES, Freire-Pritchett P, Kelava I, Wunderlich S, Martin U, Wray GA, McDole K, Lancaster MA. An early cell shape transition drives evolutionary expansion of the human forebrain. Cell. PMID 33765444 DOI: 10.1016/j.cell.2021.02.050  0.305
2020 Pellegrini L, Bonfio C, Chadwick J, Begum F, Skehel M, Lancaster MA. Human CNS barrier-forming organoids with cerebrospinal fluid production. Science (New York, N.Y.). PMID 32527923 DOI: 10.1126/Science.Aaz5626  0.332
2019 Benito-Kwiecinski S, Lancaster MA. Brain Organoids: Human Neurodevelopment in a Dish. Cold Spring Harbor Perspectives in Biology. PMID 31767649 DOI: 10.1101/Cshperspect.A035709  0.448
2019 Lancaster MA, Huch M. Disease modelling in human organoids. Disease Models & Mechanisms. 12. PMID 31383635 DOI: 10.1242/Dmm.039347  0.41
2019 Giandomenico SL, Mierau SB, Gibbons GM, Wenger LMD, Masullo L, Sit T, Sutcliffe M, Boulanger J, Tripodi M, Derivery E, Paulsen O, Lakatos A, Lancaster MA. Cerebral organoids at the air-liquid interface generate diverse nerve tracts with functional output. Nature Neuroscience. 22: 669-679. PMID 30886407 DOI: 10.1038/S41593-019-0350-2  0.372
2019 Lancaster MA. An Electric Take on Neural Fate and Cortical Development. Developmental Cell. 48: 1-2. PMID 30620896 DOI: 10.1016/J.Devcel.2018.12.014  0.359
2018 Jabaudon D, Lancaster M. Exploring landscapes of brain morphogenesis with organoids. Development (Cambridge, England). 145. PMID 30455367 DOI: 10.1242/Dev.172049  0.389
2018 Lancaster MA, Corsini NS, Wolfinger S, Gustafson EH, Phillips AW, Burkard TR, Otani T, Livesey FJ, Knoblich JA. Publisher Correction: Guided self-organization and cortical plate formation in human brain organoids. Nature Biotechnology. 36: 1016. PMID 30307926 DOI: 10.1038/Nbt1018-1016A  0.611
2018 Lancaster MA. Brain organoids get vascularized. Nature Biotechnology. 36: 407-408. PMID 29734310 DOI: 10.1038/Nbt.4133  0.339
2018 Lancaster MA. Crinkle-Cut Brain Organoids. Cell Stem Cell. 22: 616-618. PMID 29727676 DOI: 10.1016/J.Stem.2018.04.011  0.343
2017 Adhya D, Annuario E, Lancaster MA, Price J, Baron-Cohen S, Srivastava DP. Understanding role of steroids in typical and atypical brain development: Advantages of using a "brain in a dish" approach. Journal of Neuroendocrinology. PMID 29024164 DOI: 10.1111/Jne.12547  0.416
2017 Lancaster MA, Corsini NS, Wolfinger S, Gustafson EH, Phillips AW, Burkard TR, Otani T, Livesey FJ, Knoblich JA. Guided self-organization and cortical plate formation in human brain organoids. Nature Biotechnology. PMID 28562594 DOI: 10.1038/Nbt.3906  0.623
2017 Sutcliffe M, Lancaster MA. A Simple Method of Generating 3D Brain Organoids Using Standard Laboratory Equipment. Methods in Molecular Biology (Clifton, N.J.). PMID 28361479 DOI: 10.1007/7651_2017_2  0.408
2017 Renner M, Lancaster MA, Bian S, Choi H, Ku T, Peer A, Chung K, Knoblich JA. Self-organized developmental patterning and differentiation in cerebral organoids. The Embo Journal. PMID 28283582 DOI: 10.15252/Embj.201694700  0.638
2017 Giandomenico SL, Lancaster MA. Probing human brain evolution and development in organoids. Current Opinion in Cell Biology. 44: 36-43. PMID 28157638 DOI: 10.1016/J.Ceb.2017.01.001  0.382
2016 Li Y, Muffat J, Omer A, Bosch I, Lancaster MA, Sur M, Gehrke L, Knoblich JA, Jaenisch R. Induction of Expansion and Folding in Human Cerebral Organoids. Cell Stem Cell. PMID 28041895 DOI: 10.1016/J.Stem.2016.11.017  0.631
2016 Luo C, Lancaster MA, Castanon R, Nery JR, Knoblich JA, Ecker JR. Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain. Cell Reports. 17: 3369-3384. PMID 28009303 DOI: 10.1016/J.Celrep.2016.12.001  0.634
2016 Kelava I, Lancaster MA. Dishing out mini-brains: Current progress and future prospects in brain organoid research. Developmental Biology. PMID 27402594 DOI: 10.1016/J.Ydbio.2016.06.037  0.434
2016 Kelava I, Lancaster MA. Stem Cell Models of Human Brain Development. Cell Stem Cell. 18: 736-48. PMID 27257762 DOI: 10.1016/J.Stem.2016.05.022  0.422
2015 Camp JG, Badsha F, Florio M, Kanton S, Gerber T, Wilsch-Bräuninger M, Lewitus E, Sykes A, Hevers W, Lancaster M, Knoblich JA, Lachmann R, Pääbo S, Huttner WB, Treutlein B. Human cerebral organoids recapitulate gene expression programs of fetal neocortex development. Proceedings of the National Academy of Sciences of the United States of America. PMID 26644564 DOI: 10.1073/Pnas.1520760112  0.646
2015 Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, et al. Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Stem Cell Reports. PMID 26610635 DOI: 10.1016/J.Stemcr.2015.10.011  0.337
2014 Lancaster MA, Knoblich JA. Generation of cerebral organoids from human pluripotent stem cells. Nature Protocols. 9: 2329-40. PMID 25188634 DOI: 10.1038/Nprot.2014.158  0.666
2014 Lancaster MA, Knoblich JA. Organogenesis in a dish: modeling development and disease using organoid technologies. Science (New York, N.Y.). 345: 1247125. PMID 25035496 DOI: 10.1126/Science.1247125  0.622
2013 Lancaster MA, Renner M, Martin CA, Wenzel D, Bicknell LS, Hurles ME, Homfray T, Penninger JM, Jackson AP, Knoblich JA. Cerebral organoids model human brain development and microcephaly. Nature. 501: 373-9. PMID 23995685 DOI: 10.1038/Nature12517  0.68
2012 Lancaster MA, Knoblich JA. Spindle orientation in mammalian cerebral cortical development. Current Opinion in Neurobiology. 22: 737-46. PMID 22554882 DOI: 10.1016/J.Conb.2012.04.003  0.597
2011 Lancaster MA, Gopal DJ, Kim J, Saleem SN, Silhavy JL, Louie CM, Thacker BE, Williams Y, Zaki MS, Gleeson JG. Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome. Nature Medicine. 17: 726-31. PMID 21623382 DOI: 10.1038/Nm.2380  0.692
2011 Lancaster MA, Schroth J, Gleeson JG. Subcellular spatial regulation of canonical Wnt signalling at the primary cilium. Nature Cell Biology. 13: 700-7. PMID 21602792 DOI: 10.1038/Ncb2259  0.505
2010 Lancaster MA, Gleeson JG. Cystic kidney disease: the role of Wnt signaling. Trends in Molecular Medicine. 16: 349-60. PMID 20576469 DOI: 10.1016/J.Molmed.2010.05.004  0.529
2010 Louie CM, Caridi G, Lopes VS, Brancati F, Kispert A, Lancaster MA, Schlossman AM, Otto EA, Leitges M, Gröne HJ, Lopez I, Gudiseva HV, O'Toole JF, Vallespin E, Ayyagari R, et al. AHI1 is required for photoreceptor outer segment development and is a modifier for retinal degeneration in nephronophthisis. Nature Genetics. 42: 175-80. PMID 20081859 DOI: 10.1038/Ng.519  0.671
2009 Lancaster MA, Louie CM, Silhavy JL, Sintasath L, Decambre M, Nigam SK, Willert K, Gleeson JG. Impaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy. Nature Medicine. 15: 1046-54. PMID 19718039 DOI: 10.1038/Nm.2010  0.665
2009 Lancaster MA, Gleeson JG. The primary cilium as a cellular signaling center: lessons from disease. Current Opinion in Genetics & Development. 19: 220-9. PMID 19477114 DOI: 10.1016/J.Gde.2009.04.008  0.586
2006 Valente EM, Silhavy JL, Brancati F, Barrano G, Krishnaswami SR, Castori M, Lancaster MA, Boltshauser E, Boccone L, Al-Gazali L, Fazzi E, Signorini S, Louie CM, Bellacchio E, et al. Mutations in CEP290, which encodes a centrosomal protein, cause pleiotropic forms of Joubert syndrome. Nature Genetics. 38: 623-5. PMID 16682970 DOI: 10.1038/Ng1805  0.683
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