| Year |
Citation |
Score |
| 2023 |
Rosenzweig AF, Wang Z, Morales-Amador A, Spotton K, Brady SF. A Family of Antibiotics That Evades Resistance by Binding Polyprenyl Phosphates. Acs Infectious Diseases. PMID 37937847 DOI: 10.1021/acsinfecdis.3c00475 |
0.328 |
|
| 2023 |
Rosenzweig AF, Burian J, Brady SF. Present and future outlooks on environmental DNA-based methods for antibiotic discovery. Current Opinion in Microbiology. 75: 102335. PMID 37327680 DOI: 10.1016/j.mib.2023.102335 |
0.391 |
|
| 2022 |
Libis V, MacIntyre LW, Mehmood R, Guerrero L, Ternei MA, Antonovsky N, Burian J, Wang Z, Brady SF. Multiplexed mobilization and expression of biosynthetic gene clusters. Nature Communications. 13: 5256. PMID 36068239 DOI: 10.1038/s41467-022-32858-0 |
0.356 |
|
| 2022 |
Wang Z, Koirala B, Hernandez Y, Brady SF. Discovery of Paenibacillaceae Family Gram-Negative-Active Cationic Lipopeptide Antibiotics Using Evolution-Guided Chemical Synthesis. Organic Letters. PMID 35776528 DOI: 10.1021/acs.orglett.2c01879 |
0.406 |
|
| 2022 |
Wang Z, Koirala B, Hernandez Y, Zimmerman M, Brady SF. Bioinformatic prospecting and synthesis of a bifunctional lipopeptide antibiotic that evades resistance. Science (New York, N.Y.). 376: 991-996. PMID 35617397 DOI: 10.1126/science.abn4213 |
0.415 |
|
| 2022 |
Wang Z, Forelli N, Hernandez Y, Ternei M, Brady SF. Lapcin, a potent dual topoisomerase I/II inhibitor discovered by soil metagenome guided total chemical synthesis. Nature Communications. 13: 842. PMID 35149673 DOI: 10.1038/s41467-022-28292-x |
0.744 |
|
| 2022 |
Wang Z, Koirala B, Hernandez Y, Zimmerman M, Park S, Perlin DS, Brady SF. A naturally inspired antibiotic to target multidrug-resistant pathogens. Nature. PMID 34987225 DOI: 10.1038/s41586-021-04264-x |
0.4 |
|
| 2022 |
Peek J, Koirala B, Brady SF. Synthesis and evaluation of dual-action kanglemycin-fluoroquinolone hybrid antibiotics. Bioorganic & Medicinal Chemistry Letters. 57: 128484. PMID 34861348 DOI: 10.1016/j.bmcl.2021.128484 |
0.335 |
|
| 2021 |
Li L, Koirala B, Hernandez Y, MacIntyre LW, Ternei MA, Russo R, Brady SF. Identification of structurally diverse menaquinone-binding antibiotics with in vivo activity against multidrug-resistant pathogens. Nature Microbiology. PMID 34949828 DOI: 10.1038/s41564-021-01013-8 |
0.403 |
|
| 2021 |
Piscotta FJ, Hoffmann HH, Choi YJ, Small GI, Ashbrook AW, Koirala B, Campbell EA, Darst SA, Rice CM, Brady SF. Metabolites with SARS-CoV-2 Inhibitory Activity Identified from Human Microbiome Commensals. Msphere. e0071121. PMID 34851166 DOI: 10.1128/mSphere.00711-21 |
0.304 |
|
| 2021 |
Wang Z, Kasper A, Mehmood R, Ternei M, Li S, Freundlich JS, Brady S. Metagenome guided analog synthesis yields improved Gram-negative active albicidin and cystobactamid type antibiotics. Angewandte Chemie (International Ed. in English). PMID 34355488 DOI: 10.1002/anie.202104874 |
0.432 |
|
| 2021 |
Li L, MacIntyre LW, Ali T, Russo R, Koirala B, Hernandez Y, Brady SF. Biosynthetic Interrogation of Soil Metagenomes Reveals Metamarin, an Uncommon Cyclomarin Congener with Activity against . Journal of Natural Products. PMID 33621083 DOI: 10.1021/acs.jnatprod.0c01104 |
0.368 |
|
| 2020 |
Dror B, Wang Z, Brady SF, Jurkevitch E, Cytryn E. Elucidating the Diversity and Potential Function of Nonribosomal Peptide and Polyketide Biosynthetic Gene Clusters in the Root Microbiome. Msystems. 5. PMID 33361322 DOI: 10.1128/mSystems.00866-20 |
0.36 |
|
| 2020 |
Li X, Sun Z, Shang Z, Forelli N, Po KHL, Chen S, Brady SF. Total Synthesis of Malacidin A by β-Hydroxyaspartic Acid Ligation Mediated Cyclization and Absolute Structure Establishment. Angewandte Chemie (International Ed. in English). PMID 32725837 DOI: 10.1002/Anie.202009092 |
0.741 |
|
| 2020 |
Chu J, Koirala B, Forelli N, Vila-Farres X, Ternei MA, Ali T, Colosimo DA, Brady SF. Synthetic-bioinformatic natural product antibiotics with diverse modes of action. Journal of the American Chemical Society. PMID 32697091 DOI: 10.1021/jacs.0c04376 |
0.753 |
|
| 2019 |
Chu J, Vila-Farres X, Brady SF. Bioactive syn-BNP cyclic peptides inspired by nonribosomal peptide synthetase gene clusters from the human microbiome. Journal of the American Chemical Society. PMID 31545899 DOI: 10.1021/jacs.9b07317 |
0.767 |
|
| 2019 |
Libis V, Antonovsky N, Zhang M, Shang Z, Montiel D, Maniko J, Ternei MA, Calle PY, Lemetre C, Owen JG, Brady SF. Uncovering the biosynthetic potential of rare metagenomic DNA using co-occurrence network analysis of targeted sequences. Nature Communications. 10: 3848. PMID 31451725 DOI: 10.1038/S41467-019-11658-Z |
0.561 |
|
| 2019 |
Wu C, Shang Z, Lemetre C, Ternei MA, Brady SF. Cadasides, calcium-dependent acidic lipopeptides from the soil metagenome that are active against multidrug resistant bacteria. Journal of the American Chemical Society. PMID 30735616 DOI: 10.1021/Jacs.8B12087 |
0.638 |
|
| 2018 |
Kim SH, Lu W, Ahmadi MK, Montiel D, Ternei MA, Brady SF. Atolypenes, Tricyclic Bacterial Sesterterpenes Discovered Using a Multiplexed In Vitro Cas9-TAR Gene Cluster Refactoring Approach. Acs Synthetic Biology. PMID 30575381 DOI: 10.1021/Acssynbio.8B00361 |
0.347 |
|
| 2018 |
Peek J, Lilic M, Montiel D, Milshteyn A, Woodworth I, Biggins JB, Ternei MA, Calle PY, Danziger M, Warrier T, Saito K, Braffman N, Fay A, Glickman MS, Darst SA, ... ... Brady SF, et al. Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nature Communications. 9: 4147. PMID 30297823 DOI: 10.1038/S41467-018-06587-2 |
0.711 |
|
| 2018 |
Cohen LJ, Esterhazy D, Kim SH, Lemetre C, Aguilar RR, Gordon EA, Pickard AJ, Cross JR, Emiliano AB, Han SM, Chu J, Vila-Farres X, Kaplitt J, Rogoz A, Calle PY, ... ... Brady SF, et al. Corrigendum: Commensal bacteria make GPCR ligands that mimic human signalling molecules. Nature. 556: 135. PMID 29620727 DOI: 10.1038/Nature25997 |
0.684 |
|
| 2018 |
Hover BM, Kim SH, Katz M, Charlop-Powers Z, Owen JG, Ternei MA, Maniko J, Estrela AB, Molina H, Park S, Perlin DS, Brady SF. Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens. Nature Microbiology. PMID 29434326 DOI: 10.1038/S41564-018-0110-1 |
0.354 |
|
| 2018 |
Vila-Farres X, Chu J, Ternei MA, Lemetre C, Park S, Perlin DS, Brady SF. An Optimized Synthetic-Bioinformatic Natural Product Antibiotic Sterilizes Multidrug-Resistant Acinetobacter baumannii-Infected Wounds. Msphere. 3. PMID 29404414 DOI: 10.1128/mSphere.00528-17 |
0.738 |
|
| 2017 |
Cohen LJ, Esterhazy D, Kim SH, Lemetre C, Aguilar RR, Gordon EA, Pickard AJ, Cross JR, Emiliano AB, Han SM, Chu J, Vila-Farres X, Kaplitt J, Rogoz A, Calle PY, ... ... Brady SF, et al. Commensal bacteria make GPCR ligands that mimic human signalling molecules. Nature. PMID 28854168 DOI: 10.1038/Nature23874 |
0.725 |
|
| 2017 |
Chu J, Vila Farres X, Inoyama D, Gallardo-Macias R, Jaskowski M, Satish S, Freundlich JS, Brady SF. Human microbiome inspired antibiotics with improved β-lactam synergy against MDR Staphylococcus aureus. Acs Infectious Diseases. PMID 28845973 DOI: 10.1021/Acsinfecdis.7B00056 |
0.741 |
|
| 2017 |
Bitok JK, Lemetre C, Ternei MA, Brady SF. Identification of biosynthetic gene clusters from metagenomic libraries using PPTase complementation in a Streptomyces host. Fems Microbiology Letters. 364. PMID 28817927 DOI: 10.1093/femsle/fnx155 |
0.365 |
|
| 2017 |
Cohen L, Han S, Huang YH, Brady SF. Identification of the Colicin V bacteriocin gene cluster by functional screening of a human microbiome metagenomic library. Acs Infectious Diseases. PMID 28810737 DOI: 10.1021/acsinfecdis.7b00081 |
0.369 |
|
| 2017 |
Vila-Farres X, Chu J, Inoyama D, Ternei MA, Lemetre C, Cohen LJ, Cho W, Reddy BV, Zebroski HA, Freundlich JS, Perlin DS, Brady SF. Antimicrobials inspired by nonribosomal peptide synthetase gene clusters. Journal of the American Chemical Society. PMID 28055186 DOI: 10.1021/Jacs.6B11861 |
0.787 |
|
| 2016 |
Riquelme C, Enes Dapkevicius ML, Miller AZ, Charlop-Powers Z, Brady S, Mason C, Cheeptham N. Biotechnological potential of Actinobacteria from Canadian and Azorean volcanic caves. Applied Microbiology and Biotechnology. PMID 27812802 DOI: 10.1007/S00253-016-7932-7 |
0.342 |
|
| 2016 |
Chu J, Vila-Farres X, Inoyama D, Ternei M, Cohen LJ, Gordon EA, Reddy BV, Charlop-Powers Z, Zebroski HA, Gallardo-Macias R, Jaskowski M, Satish S, Park S, Perlin DS, Freundlich JS, ... Brady SF, et al. Discovery of MRSA active antibiotics using primary sequence from the human microbiome. Nature Chemical Biology. PMID 27748750 DOI: 10.1038/Nchembio.2207 |
0.706 |
|
| 2016 |
Iqbal HA, Low-Beinart L, Obiajulu JU, Brady SF. Natural Product Discovery through Improved Functional Metagenomics in Streptomyces. Journal of the American Chemical Society. PMID 27447056 DOI: 10.1021/jacs.6b02921 |
0.364 |
|
| 2016 |
Kang HS, Charlop-Powers Z, Brady SF. Multiplexed CRISPR/Cas9 and TAR-mediated promoter engineering of natural product biosynthetic gene clusters in yeast. Acs Synthetic Biology. PMID 27197732 DOI: 10.1021/Acssynbio.6B00080 |
0.328 |
|
| 2015 |
Katz M, Hover BM, Brady SF. Culture-independent discovery of natural products from soil metagenomes. Journal of Industrial Microbiology & Biotechnology. PMID 26586404 DOI: 10.1007/s10295-015-1706-6 |
0.344 |
|
| 2015 |
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, ... ... Brady SF, et al. Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31. PMID 26284661 DOI: 10.1038/Nchembio.1890 |
0.768 |
|
| 2015 |
Cohen LJ, Kang HS, Chu J, Huang YH, Gordon EA, Reddy BV, Ternei MA, Craig JW, Brady SF. Functional metagenomic discovery of bacterial effectors in the human microbiome and isolation of commendamide, a GPCR G2A/132 agonist. Proceedings of the National Academy of Sciences of the United States of America. 112: E4825-34. PMID 26283367 DOI: 10.1073/Pnas.1508737112 |
0.731 |
|
| 2015 |
Montiel D, Kang HS, Chang FY, Charlop-Powers Z, Brady SF. Yeast homologous recombination-based promoter engineering for the activation of silent natural product biosynthetic gene clusters. Proceedings of the National Academy of Sciences of the United States of America. PMID 26150486 DOI: 10.1073/Pnas.1507606112 |
0.339 |
|
| 2015 |
Chang FY, Ternei MA, Calle PY, Brady SF. Targeted metagenomics: finding rare tryptophan dimer natural products in the environment. Journal of the American Chemical Society. 137: 6044-52. PMID 25872030 DOI: 10.1021/jacs.5b01968 |
0.351 |
|
| 2015 |
Owen JG, Charlop-Powers Z, Smith AG, Ternei MA, Calle PY, Reddy BV, Montiel D, Brady SF. Multiplexed metagenome mining using short DNA sequence tags facilitates targeted discovery of epoxyketone proteasome inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 112: 4221-6. PMID 25831524 DOI: 10.1073/Pnas.1501124112 |
0.343 |
|
| 2015 |
Charlop-Powers Z, Owen JG, Reddy BV, Ternei MA, Guimarães DO, de Frias UA, Pupo MT, Seepe P, Feng Z, Brady SF. Global biogeographic sampling of bacterial secondary metabolism. Elife. 4: e05048. PMID 25599565 DOI: 10.7554/Elife.05048 |
0.353 |
|
| 2014 |
Kang HS, Brady SF. Mining soil metagenomes to better understand the evolution of natural product structural diversity: pentangular polyphenols as a case study. Journal of the American Chemical Society. 136: 18111-9. PMID 25521786 DOI: 10.1021/ja510606j |
0.366 |
|
| 2014 |
Biggins JB, Kang HS, Ternei MA, DeShazer D, Brady SF. The chemical arsenal of Burkholderia pseudomallei is essential for pathogenicity. Journal of the American Chemical Society. 136: 9484-90. PMID 24884988 DOI: 10.1021/ja504617n |
0.718 |
|
| 2014 |
Kang HS, Brady SF. Arixanthomycins A-C: Phylogeny-guided discovery of biologically active eDNA-derived pentangular polyphenols. Acs Chemical Biology. 9: 1267-72. PMID 24730509 DOI: 10.1021/cb500141b |
0.33 |
|
| 2014 |
Chang FY, Brady SF. Characterization of an environmental DNA-derived gene cluster that encodes the bisindolylmaleimide methylarcyriarubin. Chembiochem : a European Journal of Chemical Biology. 15: 815-21. PMID 24648189 DOI: 10.1002/cbic.201300756 |
0.354 |
|
| 2014 |
Biggins JB, Kang HS, Ternei MA, Deshazer D, Brady SF. The chemical arsenal of burkholderia pseudomallei is essential for pathogenicity Journal of the American Chemical Society. 136: 9484-9490. DOI: 10.1021/ja504617n |
0.652 |
|
| 2013 |
Chang FY, Ternei MA, Calle PY, Brady SF. Discovery and synthetic refactoring of tryptophan dimer gene clusters from the environment. Journal of the American Chemical Society. 135: 17906-12. PMID 24171465 DOI: 10.1021/ja408683p |
0.319 |
|
| 2013 |
Owen JG, Reddy BV, Ternei MA, Charlop-Powers Z, Calle PY, Kim JH, Brady SF. Mapping gene clusters within arrayed metagenomic libraries to expand the structural diversity of biomedically relevant natural products. Proceedings of the National Academy of Sciences of the United States of America. 110: 11797-802. PMID 23824289 DOI: 10.1073/Pnas.1222159110 |
0.369 |
|
| 2013 |
Chang FY, Brady SF. Discovery of indolotryptoline antiproliferative agents by homology-guided metagenomic screening. Proceedings of the National Academy of Sciences of the United States of America. 110: 2478-83. PMID 23302687 DOI: 10.1073/pnas.1218073110 |
0.37 |
|
| 2013 |
Charlop-Powers Z, Banik JJ, Owen JG, Craig JW, Brady SF. Selective enrichment of environmental DNA libraries for genes encoding nonribosomal peptides and polyketides by phosphopantetheine transferase-dependent complementation of siderophore biosynthesis. Acs Chemical Biology. 8: 138-43. PMID 23072412 DOI: 10.1021/Cb3004918 |
0.352 |
|
| 2012 |
Kallifidas D, Kang HS, Brady SF. Tetarimycin A, an MRSA-active antibiotic identified through induced expression of environmental DNA gene clusters. Journal of the American Chemical Society. 134: 19552-5. PMID 23157252 DOI: 10.1021/Ja3093828 |
0.396 |
|
| 2012 |
Kallifidas D, Brady SF. Reassembly of functionally intact environmental DNA-derived biosynthetic gene clusters. Methods in Enzymology. 517: 225-39. PMID 23084941 DOI: 10.1016/B978-0-12-404634-4.00011-5 |
0.354 |
|
| 2012 |
Biggins JB, Ternei MA, Brady SF. Malleilactone, a polyketide synthase-derived virulence factor encoded by the cryptic secondary metabolome of Burkholderia pseudomallei group pathogens. Journal of the American Chemical Society. 134: 13192-5. PMID 22765305 DOI: 10.1021/ja3052156 |
0.726 |
|
| 2012 |
Reddy BV, Kallifidas D, Kim JH, Charlop-Powers Z, Feng Z, Brady SF. Natural product biosynthetic gene diversity in geographically distinct soil microbiomes. Applied and Environmental Microbiology. 78: 3744-52. PMID 22427492 DOI: 10.1128/Aem.00102-12 |
0.337 |
|
| 2012 |
Feng Z, Chakraborty D, Dewell SB, Reddy BV, Brady SF. Environmental DNA-encoded antibiotics fasamycins A and B inhibit FabF in type II fatty acid biosynthesis. Journal of the American Chemical Society. 134: 2981-7. PMID 22224500 DOI: 10.1021/Ja207662W |
0.396 |
|
| 2011 |
Feng Z, Kallifidas D, Brady SF. Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites. Proceedings of the National Academy of Sciences of the United States of America. 108: 12629-34. PMID 21768346 DOI: 10.1073/Pnas.1103921108 |
0.392 |
|
| 2011 |
Chang FY, Brady SF. Cloning and characterization of an environmental DNA-derived gene cluster that encodes the biosynthesis of the antitumor substance BE-54017. Journal of the American Chemical Society. 133: 9996-9. PMID 21542592 DOI: 10.1021/ja2022653 |
0.328 |
|
| 2011 |
Biggins JB, Gleber CD, Brady SF. Acyldepsipeptide HDAC inhibitor production induced in Burkholderia thailandensis. Organic Letters. 13: 1536-9. PMID 21348454 DOI: 10.1021/ol200225v |
0.693 |
|
| 2011 |
Biggins JB, Liu X, Feng Z, Brady SF. Metabolites from the induced expression of cryptic single operons found in the genome of Burkholderia pseudomallei. Journal of the American Chemical Society. 133: 1638-41. PMID 21247113 DOI: 10.1021/ja1087369 |
0.699 |
|
| 2010 |
Banik JJ, Craig JW, Calle PY, Brady SF. Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products. Journal of the American Chemical Society. 132: 15661-70. PMID 20945895 DOI: 10.1021/ja105825a |
0.319 |
|
| 2010 |
Banik JJ, Brady SF. Recent application of metagenomic approaches toward the discovery of antimicrobials and other bioactive small molecules. Current Opinion in Microbiology. 13: 603-9. PMID 20884282 DOI: 10.1016/j.mib.2010.08.012 |
0.359 |
|
| 2010 |
Feng Z, Kim JH, Brady SF. Fluostatins produced by the heterologous expression of a TAR reassembled environmental DNA derived type II PKS gene cluster. Journal of the American Chemical Society. 132: 11902-3. PMID 20690632 DOI: 10.1021/ja104550p |
0.347 |
|
| 2010 |
Kim JH, Feng Z, Bauer JD, Kallifidas D, Calle PY, Brady SF. Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR. Biopolymers. 93: 833-44. PMID 20577994 DOI: 10.1002/Bip.21450 |
0.365 |
|
| 2008 |
Banik JJ, Brady SF. Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary. Proceedings of the National Academy of Sciences of the United States of America. 105: 17273-7. PMID 18987322 DOI: 10.1073/pnas.0807564105 |
0.37 |
|
| 2008 |
Clarke-Pearson MF, Brady SF. Paerucumarin, a new metabolite produced by the pvc gene cluster from Pseudomonas aeruginosa. Journal of Bacteriology. 190: 6927-30. PMID 18689486 DOI: 10.1128/JB.00801-08 |
0.327 |
|
| 2007 |
Brady SF, Bauer JD, Clarke-Pearson MF, Daniels R. Natural products from isnA-containing biosynthetic gene clusters recovered from the genomes of cultured and uncultured bacteria. Journal of the American Chemical Society. 129: 12102-3. PMID 17880089 DOI: 10.1021/ja075492v |
0.333 |
|
| 2007 |
Clardy J, Brady SF. Cyclic AMP directly activates NasP, an N-acyl amino acid antibiotic biosynthetic enzyme cloned from an uncultured beta-proteobacterium. Journal of Bacteriology. 189: 6487-9. PMID 17586635 DOI: 10.1128/Jb.00457-07 |
0.392 |
|
| 2006 |
Maloney KN, Hao W, Xu J, Gibbons J, Hucul J, Roll D, Brady SF, Schroeder FC, Clardy J. Phaeosphaeride A, an inhibitor of STAT3-dependent signaling isolated from an endophytic fungus. Organic Letters. 8: 4067-70. PMID 16928075 DOI: 10.1021/Ol061556F |
0.721 |
|
| 2005 |
Brady SF, Clardy J. Systematic investigation of the Escherichia coli metabolome for the biosynthetic origin of an isocyanide carbon atom. Angewandte Chemie (International Ed. in English). 44: 7045-8. PMID 16217820 DOI: 10.1002/Anie.200501942 |
0.4 |
|
| 2005 |
Brady SF, Clardy J. Cloning and heterologous expression of isocyanide biosynthetic genes from environmental DNA. Angewandte Chemie (International Ed. in English). 44: 7063-5. PMID 16206308 DOI: 10.1002/Anie.200501941 |
0.437 |
|
| 2005 |
Brady SF, Clardy J. N-acyl derivatives of arginine and tryptophan isolated from environmental DNA expressed in Escherichia coli. Organic Letters. 7: 3613-6. PMID 16092832 DOI: 10.1021/Ol0509585 |
0.513 |
|
| 2005 |
Weibel DB, Lee A, Mayer M, Brady SF, Bruzewicz D, Yang J, Diluzio WR, Clardy J, Whitesides GM. Bacterial printing press that regenerates its ink: contact-printing bacteria using hydrogel stamps. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 6436-42. PMID 15982051 DOI: 10.1021/La047173C |
0.358 |
|
| 2004 |
Brady SF, Chao CJ, Clardy J. Long-chain N-acyltyrosine synthases from environmental DNA. Applied and Environmental Microbiology. 70: 6865-70. PMID 15528554 DOI: 10.1128/Aem.70.11.6865-6870.2004 |
0.506 |
|
| 2004 |
Brady SF, Clardy J. Palmitoylputrescine, an antibiotic isolated from the heterologous expression of DNA extracted from bromeliad tank water. Journal of Natural Products. 67: 1283-6. PMID 15332842 DOI: 10.1021/Np0499766 |
0.506 |
|
| 2003 |
Brady SF, Clardy J. Synthesis of long-chain fatty acid enol esters isolated from an environmental DNA clone. Organic Letters. 5: 121-4. PMID 12529120 DOI: 10.1021/Ol0267681 |
0.482 |
|
| 2002 |
Gillespie DE, Brady SF, Bettermann AD, Cianciotto NP, Liles MR, Rondon MR, Clardy J, Goodman RM, Handelsman J. Isolation of antibiotics turbomycin a and B from a metagenomic library of soil microbial DNA. Applied and Environmental Microbiology. 68: 4301-6. PMID 12200279 DOI: 10.1128/Aem.68.9.4301-4306.2002 |
0.522 |
|
| 2002 |
Brady SF, Chao CJ, Clardy J. New natural product families from an environmental DNA (eDNA) gene cluster. Journal of the American Chemical Society. 124: 9968-9. PMID 12188643 DOI: 10.1021/Ja0268985 |
0.564 |
|
| 2001 |
Brady SF, Bondi SM, Clardy J. The guanacastepenes: a highly diverse family of secondary metabolites produced by an endophytic fungus. Journal of the American Chemical Society. 123: 9900-1. PMID 11583556 DOI: 10.1021/Ja016176Y |
0.43 |
|
| 2001 |
Brady SF, Chao CJ, Handelsman J, Clardy J. Cloning and heterologous expression of a natural product biosynthetic gene cluster from eDNA. Organic Letters. 3: 1981-4. PMID 11418029 DOI: 10.1021/Ol015949K |
0.559 |
|
| 2000 |
Brady SF, Singh MP, Janso JE, Clardy J. Cytoskyrins A and B, new BIA active bisanthraquinones isolated from an endophytic fungus. Organic Letters. 2: 4047-9. PMID 11112640 DOI: 10.1021/Ol006681K |
0.491 |
|
| 2000 |
Brady SF, Wagenaar MM, Singh MP, Janso JE, Clardy J. The cytosporones, new octaketide antibiotics isolated from an endophytic fungus. Organic Letters. 2: 4043-6. PMID 11112639 DOI: 10.1021/Ol006680S |
0.724 |
|
| 2000 |
Brady SF, Clardy J. CR377, a new pentaketide antifungal agent isolated from an endophytic fungus. Journal of Natural Products. 63: 1447-8. PMID 11076576 DOI: 10.1021/Np990568P |
0.456 |
|
| 2000 |
Rondon MR, August PR, Bettermann AD, Brady SF, Grossman TH, Liles MR, Loiacono KA, Lynch BA, MacNeil IA, Minor C, Tiong CL, Gilman M, Osburne MS, Clardy J, Handelsman J, et al. Cloning the soil metagenome: a strategy for accessing the genetic and functional diversity of uncultured microorganisms. Applied and Environmental Microbiology. 66: 2541-7. PMID 10831436 DOI: 10.1128/Aem.66.6.2541-2547.2000 |
0.525 |
|
| 2000 |
Singh MP, Janso JE, Luckman SW, Brady SF, Clardy J, Greenstein M, Maiese WM. Biological activity of guanacastepene, a novel diterpenoid antibiotic produced by an unidentified fungus CR115. The Journal of Antibiotics. 53: 256-61. PMID 10819296 DOI: 10.7164/Antibiotics.53.256 |
0.46 |
|
| 2000 |
Brady SF, Singh MP, Janso JE, Clardy J. Guanacastepene, a fungal-derived diterpene antibiotic with a new carbon skeleton Journal of the American Chemical Society. 122: 2116-2117. DOI: 10.1021/Ja993835M |
0.37 |
|
| 2000 |
Brady SF, Clardy J. Long-chain N-acyl amino acid antibiotics isolated from heterologously expressed environmental DNA [20] Journal of the American Chemical Society. 122: 12903-12904. DOI: 10.1021/Ja002990U |
0.377 |
|
| 1999 |
Stohl EA, Brady SF, Clardy J, Handelsman J. ZmaR, a novel and widespread antibiotic resistance determinant that acetylates zwittermicin A. Journal of Bacteriology. 181: 5455-60. PMID 10464220 DOI: 10.1128/Jb.181.17.5455-5460.1999 |
0.515 |
|
| 1998 |
Handelsman J, Rondon MR, Brady SF, Clardy J, Goodman RM. Molecular biological access to the chemistry of unknown soil microbes: a new frontier for natural products. Chemistry & Biology. 5: R245-9. PMID 9818143 DOI: 10.1016/S1074-5521(98)90108-9 |
0.444 |
|
| Show low-probability matches. |