| Year |
Citation |
Score |
| 2023 |
Hogan G, Winer BY, Ahodantin J, Sellau J, Huang T, Douam F, Funaki M, Chiriboga L, Su L, Ploss A. Persistent hepatitis B virus and HIV coinfections in dually humanized mice engrafted with human liver and immune system. Journal of Medical Virology. 95: e28930. PMID 37403703 DOI: 10.1002/jmv.28930 |
0.333 |
|
| 2022 |
Ahodantin J, Nio K, Funaki M, Zhai X, Wilson E, Kottilil S, Cheng L, Li G, Su L. Type I interferons and TGF-β cooperate to induce liver fibrosis during HIV-1 infection under antiretroviral therapy. Jci Insight. PMID 35639478 DOI: 10.1172/jci.insight.152738 |
0.33 |
|
| 2021 |
Novotny LA, Evans JG, Su L, Guo H, Meissner EG. Review of Lambda Interferons in Hepatitis B Virus Infection: Outcomes and Therapeutic Strategies. Viruses. 13. PMID 34207487 DOI: 10.3390/v13061090 |
0.751 |
|
| 2021 |
Guo H, Wang Q, Ghneim K, Wang L, Rampanelli E, Holley-Guthrie E, Cheng L, Garrido C, Margolis DM, Eller LA, Robb ML, Sekaly RP, Chen X, Su L, Ting JP. Multi-omics analyses reveal that HIV-1 alters CD4 T cell immunometabolism to fuel virus replication. Nature Immunology. PMID 33767427 DOI: 10.1038/s41590-021-00898-1 |
0.412 |
|
| 2021 |
Lichtman EI, Du H, Shou P, Song F, Suzuki K, Ahn S, Li G, Ferrone S, Su L, Savoldo B, Dotti G. Preclinical Evaluation of B7-H3-Specific Chimeric Antigen Receptor T cells for the Treatment of Acute Myeloid Leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33531429 DOI: 10.1182/Blood-2018-99-113468 |
0.34 |
|
| 2020 |
Godot V, Tcherakian C, Gil L, Cervera-Marzal I, Li G, Cheng L, Ortonne N, Lelièvre JD, Pantaleo G, Fenwick C, Centlivre M, Mouquet H, Cardinaud S, Zurawski SM, Zurawski G, ... ... Su L, et al. TLR-9 agonist and CD40-targeting vaccination induces HIV-1 envelope-specific B cells with a diversified immunoglobulin repertoire in humanized mice. Plos Pathogens. 16: e1009025. PMID 33253297 DOI: 10.1371/journal.ppat.1009025 |
0.318 |
|
| 2020 |
Zhang Y, Ma Z, Wang Y, Boyer J, Ni G, Cheng L, Su S, Zhang Z, Zhu Z, Qian J, Su L, Zhang Q, Damania B, Liu P. Streptavidin Promotes DNA Binding and Activation of cGAS to Enhance Innate Immunity. Iscience. 23: 101463. PMID 32861998 DOI: 10.1016/J.Isci.2020.101463 |
0.311 |
|
| 2020 |
Guo Z, Wang G, Wu B, Chou WC, Cheng L, Zhou C, Lou J, Wu D, Su L, Zheng J, Pan-Yun Ting J, Wan YY. DCAF1 regulates Treg senescence via the ROS axis during immunological ageing. The Journal of Clinical Investigation. PMID 32730228 DOI: 10.1172/Jci136466 |
0.343 |
|
| 2020 |
Cheng L, Yu H, Wrobel JA, Li G, Liu P, Hu Z, Xu XN, Su L. Identification of pathogenic TRAIL-expressing innate immune cells during HIV-1 infection in humanized mice by scRNA-seq. Jci Insight. PMID 32406872 DOI: 10.1172/Jci.Insight.135344 |
0.516 |
|
| 2020 |
Sun C, Shou P, Du H, Hirabayashi K, Chen Y, Herring LE, Ahn S, Xu Y, Suzuki K, Li G, Tsahouridis O, Su L, Savoldo B, Dotti G. THEMIS-SHP1 Recruitment by 4-1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells. Cancer Cell. PMID 32004441 DOI: 10.1016/j.ccell.2019.12.014 |
0.313 |
|
| 2020 |
Li F, Wang Z, Hu F, Su L. Cell Culture Models and Animal Models for HBV Study. Advances in Experimental Medicine and Biology. 1179: 109-135. PMID 31741335 DOI: 10.1007/978-981-13-9151-4_5 |
0.346 |
|
| 2019 |
Tan G, Yi Z, Song H, Xu F, Li F, Aliyari R, Zhang H, Du P, Ding Y, Niu J, Wang X, Su L, Qin FX, Cheng G. Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation. Cell Reports. 29: 3551-3563.e3. PMID 31825835 DOI: 10.1016/J.Celrep.2019.11.041 |
0.327 |
|
| 2019 |
Bi W, Xu W, Cheng L, Xue J, Wang Q, Yu F, Xia S, Wang Q, Li G, Qin C, Lu L, Su L, Jiang S. IgG Fc-binding motif-conjugated HIV-1 fusion inhibitor exhibits improved potency and in vivo half-life: Potential application in combination with broad neutralizing antibodies. Plos Pathogens. 15: e1008082. PMID 31805154 DOI: 10.1371/Journal.Ppat.1008082 |
0.418 |
|
| 2019 |
Wang Q, Su L. Vpr Enhances HIV-1 Env Processing and Virion Infectivity in Macrophages by Modulating TET2-Dependent IFITM3 Expression. Mbio. 10. PMID 31431548 DOI: 10.1128/Mbio.01344-19 |
0.45 |
|
| 2019 |
Allen TM, Brehm MA, Bridges S, Ferguson S, Kumar P, Mirochnitchenko O, Palucka K, Pelanda R, Sanders-Beer B, Shultz LD, Su L, PrabhuDas M. Humanized immune system mouse models: progress, challenges and opportunities. Nature Immunology. PMID 31160798 DOI: 10.1038/S41590-019-0416-Z |
0.303 |
|
| 2019 |
Su L. Pathogenic Role of Type I Interferons in HIV-Induced Immune Impairments in Humanized Mice. Current Hiv/Aids Reports. PMID 31055732 DOI: 10.1007/s11904-019-00444-7 |
0.311 |
|
| 2019 |
Nunoya JI, Masuda M, Ye C, Su L. Chimeric Antigen Receptor T Cell Bearing Herpes Virus Entry Mediator Co-stimulatory Signal Domain Exhibits High Functional Potency. Molecular Therapy Oncolytics. 14: 27-37. PMID 31011630 DOI: 10.1016/J.Omto.2019.03.002 |
0.427 |
|
| 2019 |
Li G, Zhang Z, Reszka-Blanco N, Li F, Chi L, Ma J, Jeffrey J, Cheng L, Su L. Specific activation of HIV-1 by a bromodomain inhibitor from monocytic cells in humanized mice under ART in vivo. Journal of Virology. PMID 30971469 DOI: 10.1128/Jvi.00233-19 |
0.511 |
|
| 2019 |
Song H, Tan G, Yang Y, Cui A, Li H, Li T, Wu Z, Yang M, Lv G, Chi X, Niu J, Zhu K, Crispe IN, Su L, Tu Z. Hepatitis B Virus-Induced Imbalance of Inflammatory and Antiviral Signaling by Differential Phosphorylation of STAT1 in Human Monocytes. Journal of Immunology (Baltimore, Md. : 1950). PMID 30842274 DOI: 10.4049/Jimmunol.1800848 |
0.344 |
|
| 2019 |
Li T, Yang Y, Song H, Li H, Cui A, Liu Y, Su L, Crispe IN, Tu Z. Activated NK cells kill hepatic stellate cells via p38/PI3K signaling in a TRAIL-involved degranulation manner. Journal of Leukocyte Biology. PMID 30748035 DOI: 10.1002/Jlb.2A0118-031Rr |
0.387 |
|
| 2019 |
Xi R, Kadur Lakshminarasimha Murthy P, Tung KL, Guy CD, Wan J, Li F, Wang Z, Li X, Varanko A, Rakhilin N, Xin Y, Liu B, Qian SB, Su L, Han Y, et al. SENP3-mediated host defense response contains HBV replication and restores protein synthesis. Plos One. 14: e0209179. PMID 30640896 DOI: 10.1371/Journal.Pone.0209179 |
0.364 |
|
| 2018 |
Cheng L, Wang Q, Li G, Banga R, Ma J, Yu H, Yasui F, Zhang Z, Pantaleo G, Perreau M, Zurawski S, Zurawski G, Levy Y, Su L. TLR3 agonist and CD40-targeting vaccination induces immune responses and reduces HIV-1 reservoirs. The Journal of Clinical Investigation. PMID 30148455 DOI: 10.1172/Jci99005 |
0.461 |
|
| 2018 |
Lv L, Wang Q, Xu Y, Tsao LC, Nakagawa T, Guo H, Su L, Xiong Y. Vpr Targets TET2 for Degradation by CRL4 E3 Ligase to Sustain IL-6 Expression and Enhance HIV-1 Replication. Molecular Cell. 70: 961-970.e5. PMID 29883611 DOI: 10.1016/J.Molcel.2018.05.007 |
0.427 |
|
| 2018 |
Cheng L, Ma J, Li G, Su L. Humanized Mice Engrafted With Human HSC Only or HSC and Thymus Support Comparable HIV-1 Replication, Immunopathology, and Responses to ART and Immune Therapy. Frontiers in Immunology. 9: 817. PMID 29725337 DOI: 10.3389/Fimmu.2018.00817 |
0.463 |
|
| 2018 |
Li D, Hu M, Liu Y, Ye P, Du P, Li CS, Cheng L, Liu P, Jiang J, Su L, Wang S, Zheng P, Liu Y. CD24-p53 axis suppresses diethylnitrosamine-induced hepatocellular carcinogenesis by sustaining intrahepatic macrophages. Cell Discovery. 4: 6. PMID 29423273 DOI: 10.1038/S41421-017-0007-9 |
0.318 |
|
| 2018 |
Zhao J, Cheng L, Wang H, Yu H, Tu B, Fu Q, Li G, Wang Q, Sun Y, Zhang X, Liu Z, Chen W, Zhang L, Su L, Zhang Z. Infection and depletion of CD4+ group-1 innate lymphoid cells by HIV-1 via type-I interferon pathway. Plos Pathogens. 14: e1006819. PMID 29304123 DOI: 10.1371/Journal.Ppat.1006819 |
0.487 |
|
| 2017 |
Pang W, Zhang GH, Jiang J, Zheng HY, Zhang LT, Zhang XL, Song JH, Zhang MX, Zhu JW, Lei AH, Tian RR, Liu XM, Zhang L, Gao G, Su L, et al. HIV-1 can infect northern pig-tailed macaques (Macaca leonina) and form viral reservoirs in vivo. Science Bulletin. 62: 1315-1324. PMID 36659293 DOI: 10.1016/j.scib.2017.09.020 |
0.331 |
|
| 2017 |
Li G, Nunoya JI, Cheng L, Reszka-Blanco N, Tsao LC, Jeffrey J, Su L. Regulatory T Cells Contribute to HIV-1 Reservoir Persistence in CD4 T Cells Through cAMP-Dependent Mechanisms in Humanized Mice In Vivo. The Journal of Infectious Diseases. PMID 29045701 DOI: 10.1093/Infdis/Jix547 |
0.514 |
|
| 2017 |
Cheng L, Zhang Z, Li G, Li F, Wang L, Zhang L, Zurawski SM, Zurawski G, Levy Y, Su L. Human innate responses and adjuvant activity of TLR ligands in vivo in mice reconstituted with a human immune system. Vaccine. PMID 28958808 DOI: 10.1016/J.Vaccine.2017.09.052 |
0.382 |
|
| 2017 |
Li H, Zhai N, Wang Z, Song H, Yang Y, Cui A, Li T, Wang G, Niu J, Crispe IN, Su L, Tu Z. Regulatory NK cells mediated between immunosuppressive monocytes and dysfunctional T cells in chronic HBV infection. Gut. PMID 28899983 DOI: 10.1136/Gutjnl-2017-314098 |
0.374 |
|
| 2017 |
Li G, Zhao J, Cheng L, Jiang Q, Kan S, Qin E, Tu B, Zhang X, Zhang L, Su L, Zhang Z. HIV-1 infection depletes human CD34+CD38- hematopoietic progenitor cells via pDC-dependent mechanisms. Plos Pathogens. 13: e1006505. PMID 28759657 DOI: 10.1371/Journal.Ppat.1006505 |
0.463 |
|
| 2017 |
Wang Y, Li Y, Li H, Song H, Zhai N, Lou L, Wang F, Zhang K, Bao W, Jin X, Su L, Tu Z. Brucella Dysregulates Monocytes and Inhibits Macrophage Polarization through LC3-Dependent Autophagy. Frontiers in Immunology. 8: 691. PMID 28659924 DOI: 10.3389/Fimmu.2017.00691 |
0.342 |
|
| 2017 |
Cheng L, Yu H, Li G, Li F, Ma J, Li J, Chi L, Zhang L, Su L. Type I interferons suppress viral replication but contribute to T cell depletion and dysfunction during chronic HIV-1 infection. Jci Insight. 2. PMID 28614789 DOI: 10.1172/Jci.Insight.94366 |
0.517 |
|
| 2017 |
Zhai N, Li H, Song H, Yang Y, Cui A, Li T, Niu J, Crispe IN, Su L, Tu Z. Hepatitis C Virus Induces MDSCs-Like Monocytes through TLR2/PI3K/AKT/STAT3 Signaling. Plos One. 12: e0170516. PMID 28114346 DOI: 10.1371/Journal.Pone.0170516 |
0.387 |
|
| 2017 |
Li F, Nio K, Yasui F, Murphy CM, Su L. Studying HBV Infection and Therapy in Immune-Deficient NOD-Rag1-/-IL2RgammaC-null (NRG) Fumarylacetoacetate Hydrolase (Fah) Knockout Mice Transplanted with Human Hepatocytes. Methods in Molecular Biology (Clifton, N.J.). 1540: 267-276. PMID 27975325 DOI: 10.1007/978-1-4939-6700-1_23 |
0.347 |
|
| 2016 |
Bility MT, Nio K, Li F, McGivern DR, Lemon SM, Feeney ER, Chung RT, Su L. Chronic hepatitis C infection-induced liver fibrogenesis is associated with M2 macrophage activation. Scientific Reports. 6: 39520. PMID 28000758 DOI: 10.1038/Srep39520 |
0.34 |
|
| 2016 |
Cheng L, Ma J, Li J, Li D, Li G, Li F, Zhang Q, Yu H, Yasui F, Ye C, Tsao LC, Hu Z, Su L, Zhang L. Blocking type I interferon signaling enhances T cell recovery and reduces HIV-1 reservoirs. The Journal of Clinical Investigation. PMID 27941247 DOI: 10.1172/Jci90745 |
0.449 |
|
| 2016 |
Ye C, Wang W, Cheng L, Li G, Wen M, Wang Q, Zhang Q, Li D, Zhou P, Su L. Glycosyl-phosphatidylinositol (GPI)-anchored anti-HIV scFv efficiently protect CD4 T cells from HIV-1 infection and deletion in hu-PBL mice. Journal of Virology. PMID 27881659 DOI: 10.1128/Jvi.01389-16 |
0.505 |
|
| 2016 |
Zhang Q, Wang Y, Zhai N, Song H, Li H, Yang Y, Li T, Guo X, Chi B, Niu J, Crispe IN, Su L, Tu Z. HCV core protein inhibits polarization and activity of both M1 and M2 macrophages through the TLR2 signaling pathway. Scientific Reports. 6: 36160. PMID 27786268 DOI: 10.1038/Srep36160 |
0.342 |
|
| 2016 |
Murphy CM, Xu Y, Li F, Nio K, Reszka-Blanco N, Li X, Wu Y, Yu Y, Xiong Y, Su L. Hepatitis B Virus X Protein Promotes Degradation of SMC5/6 to Enhance HBV Replication. Cell Reports. 16: 2846-2854. PMID 27626656 DOI: 10.1016/J.Celrep.2016.08.026 |
0.349 |
|
| 2016 |
Brezar V, Godot V, Cheng L, Su L, Lévy Y, Seddiki N. T-Regulatory Cells and Vaccination "Pay Attention and Do Not Neglect Them": Lessons from HIV and Cancer Vaccine Trials. Vaccines. 4. PMID 27608046 DOI: 10.3390/Vaccines4030030 |
0.386 |
|
| 2016 |
Pang X, Wang Z, Zhai N, Zhang Q, Song H, Zhang Y, Li T, Li H, Su L, Niu J, Tu Z. IL-10 plays a central regulatory role in the cytokines induced by hepatitis C virus core protein and polyinosinic acid:polycytodylic acid. International Immunopharmacology. 38: 284-290. PMID 27337528 DOI: 10.1016/J.Intimp.2016.06.013 |
0.335 |
|
| 2016 |
Guo H, König R, Deng M, Riess M, Mo J, Zhang L, Petrucelli A, Yoh SM, Barefoot B, Samo M, Sempowski GD, Zhang A, Colberg-Poley AM, Feng H, Lemon SM, ... ... Su L, et al. NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses. Cell Host & Microbe. 19: 515-528. PMID 27078069 DOI: 10.1016/J.Chom.2016.03.001 |
0.394 |
|
| 2016 |
Tsao LC, Guo H, Jeffrey J, Hoxie JA, Su L. CCR5 interaction with HIV-1 Env contributes to Env-induced depletion of CD4 T cells in vitro and in vivo. Retrovirology. 13: 22. PMID 27026376 DOI: 10.1186/S12977-016-0255-Z |
0.517 |
|
| 2016 |
Zhu D, Liu L, Yang D, Fu S, Bian Y, Sun Z, He J, Su L, Zhang L, Peng H, Fu YX. Clearing Persistent Extracellular Antigen of Hepatitis B Virus: An Immunomodulatory Strategy To Reverse Tolerance for an Effective Therapeutic Vaccination. Journal of Immunology (Baltimore, Md. : 1950). PMID 26936879 DOI: 10.4049/Jimmunol.1502061 |
0.354 |
|
| 2015 |
Whitehurst CB, Li G, Montgomery SA, Montgomery ND, Su L, Pagano JS. Knockout of Epstein-Barr Virus BPLF1 Retards B-Cell Transformation and Lymphoma Formation in Humanized Mice. Mbio. 6. PMID 26489865 DOI: 10.1128/Mbio.01574-15 |
0.358 |
|
| 2015 |
Zhang Z, Cheng L, Zhao J, Li G, Zhang L, Chen W, Nie W, Reszka-Blanco NJ, Wang FS, Su L. Plasmacytoid dendritic cells promote HIV-1-induced group 3 innate lymphoid cell depletion. The Journal of Clinical Investigation. 125: 3692-703. PMID 26301812 DOI: 10.1172/Jci82124 |
0.496 |
|
| 2015 |
Wang Y, McGivern DR, Cheng L, Li G, Lemon SM, Niu J, Su L, Reszka-Blanco NJ. Ribavirin Contributes to Hepatitis C Virus Suppression by Augmenting pDC Activation and Type 1 IFN Production. Plos One. 10: e0135232. PMID 26274905 DOI: 10.1371/Journal.Pone.0135232 |
0.332 |
|
| 2015 |
Cheng M, Zhang X, Yu H, Du P, Plumas J, Chaperot L, Su L, Zhang L. Characterization of species-specific genes regulated by E2-2 in human plasmacytoid dendritic cells. Scientific Reports. 5: 10752. PMID 26182859 DOI: 10.1038/Srep10752 |
0.337 |
|
| 2015 |
Cheng L, Li F, Bility MT, Murphy CM, Su L. Modeling hepatitis B virus infection, immunopathology and therapy in mice. Antiviral Research. PMID 26099683 DOI: 10.1016/J.Antiviral.2015.06.012 |
0.322 |
|
| 2015 |
Jiao YM, Liu CE, Luo LJ, Zhu WJ, Zhang T, Zhang LG, Su LS, Li HJ, Wu H. CD4+CD25+CD127-Regulatory Cells Play Multiple Roles in Maintaining HIV-1 p24 Production in Patients on Long-term Treatment: HIV-1 p24 Producing Cells and Suppression of Anti-HIV Immunity. International Journal of Infectious Diseases : Ijid : Official Publication of the International Society For Infectious Diseases. PMID 26095899 DOI: 10.1016/j.ijid.2015.06.008 |
0.383 |
|
| 2015 |
Reszka-Blanco NJ, Sivaraman V, Zhang L, Su L. HIV-1 Env and Nef Cooperatively Contribute to Plasmacytoid Dendritic Cell Activation via CD4-Dependent Mechanisms. Journal of Virology. 89: 7604-11. PMID 25972534 DOI: 10.1128/Jvi.00695-15 |
0.46 |
|
| 2015 |
Guo H, Zhang J, Zhang X, Wang Y, Yu H, Yin X, Li J, Du P, Plumas J, Chaperot L, Chen J, Su L, Liu Y, Zhang L. SCARB2/LIMP-2 Regulates IFN Production of Plasmacytoid Dendritic Cells by Mediating Endosomal Translocation of TLR9 and Nuclear Translocation of IRF7. Journal of Immunology (Baltimore, Md. : 1950). 194: 4737-49. PMID 25862818 DOI: 10.4049/Jimmunol.1402312 |
0.359 |
|
| 2014 |
Cheng L, Du X, Su L, Wang S. Immunotherapy of metastatic and autochthonous liver cancer with IL-15/IL-15Rα fusion protein. Oncoimmunology. 3: e963409. PMID 25941592 DOI: 10.4161/21624011.2014.963409 |
0.332 |
|
| 2014 |
Zhai N, Chi X, Li T, Song H, Li H, Jin X, Crispe IN, Su L, Niu J, Tu Z. Hepatitis C virus core protein triggers expansion and activation of CD4(+)CD25(+) regulatory T cells in chronic hepatitis C patients. Cellular & Molecular Immunology. PMID 25531392 DOI: 10.1038/Cmi.2014.119 |
0.398 |
|
| 2014 |
Chen Y, Wang S, Yi Z, Tian H, Aliyari R, Li Y, Chen G, Liu P, Zhong J, Chen X, Du P, Su L, Qin FX, Deng H, Cheng G. Interferon-inducible cholesterol-25-hydroxylase inhibits hepatitis C virus replication via distinct mechanisms. Scientific Reports. 4: 7242. PMID 25467815 DOI: 10.1038/Srep07242 |
0.311 |
|
| 2014 |
Bility MT, Curtis A, Su L. A chimeric mouse model to study immunopathogenesis of HCV infection. Methods in Molecular Biology (Clifton, N.J.). 1213: 379-88. PMID 25173399 DOI: 10.1007/978-1-4939-1453-1_31 |
0.33 |
|
| 2014 |
Li G, Cheng M, Nunoya J, Cheng L, Guo H, Yu H, Liu YJ, Su L, Zhang L. Plasmacytoid dendritic cells suppress HIV-1 replication but contribute to HIV-1 induced immunopathogenesis in humanized mice. Plos Pathogens. 10: e1004291. PMID 25077616 DOI: 10.1371/Journal.Ppat.1004291 |
0.49 |
|
| 2014 |
Cheng L, Du X, Wang Z, Ju J, Jia M, Huang Q, Xing Q, Xu M, Tan Y, Liu M, Du P, Su L, Wang S. Hyper-IL-15 suppresses metastatic and autochthonous liver cancer by promoting tumour-specific CD8+ T cell responses. Journal of Hepatology. 61: 1297-303. PMID 25016226 DOI: 10.1016/J.Jhep.2014.07.004 |
0.411 |
|
| 2014 |
Guo H, Gao J, Taxman DJ, Ting JP, Su L. HIV-1 infection induces interleukin-1β production via TLR8 protein-dependent and NLRP3 inflammasome mechanisms in human monocytes. The Journal of Biological Chemistry. 289: 21716-26. PMID 24939850 DOI: 10.1074/Jbc.M114.566620 |
0.395 |
|
| 2014 |
Li F, Cowley DO, Banner D, Holle E, Zhang L, Su L. Efficient genetic manipulation of the NOD-Rag1-/-IL2RgammaC-null mouse by combining in vitro fertilization and CRISPR/Cas9 technology. Scientific Reports. 4: 5290. PMID 24936832 DOI: 10.1038/Srep05290 |
0.316 |
|
| 2014 |
Bility MT, Cheng L, Zhang Z, Luan Y, Li F, Chi L, Zhang L, Tu Z, Gao Y, Fu Y, Niu J, Wang F, Su L. Hepatitis B virus infection and immunopathogenesis in a humanized mouse model: induction of human-specific liver fibrosis and M2-like macrophages. Plos Pathogens. 10: e1004032. PMID 24651854 DOI: 10.1371/Journal.Ppat.1004032 |
0.362 |
|
| 2014 |
Nunoya J, Washburn ML, Kovalev GI, Su L. Regulatory T cells prevent liver fibrosis during HIV type 1 infection in a humanized mouse model. The Journal of Infectious Diseases. 209: 1039-44. PMID 24133182 DOI: 10.1093/Infdis/Jit548 |
0.784 |
|
| 2014 |
Yang D, Liu L, Zhu D, Peng H, Su L, Fu YX, Zhang L. A mouse model for HBV immunotolerance and immunotherapy. Cellular & Molecular Immunology. 11: 71-8. PMID 24076617 DOI: 10.1038/Cmi.2013.43 |
0.328 |
|
| 2013 |
Tu Z, Zhang P, Li H, Niu J, Jin X, Su L. Cross-linking of CD81 by HCV-E2 protein inhibits human intrahepatic plasmacytoid dendritic cells response to CpG-ODN. Cellular Immunology. 284: 98-103. PMID 23954883 DOI: 10.1016/J.Cellimm.2013.07.012 |
0.367 |
|
| 2013 |
Zhang Z, Fu J, Xu X, Wang S, Xu R, Zhao M, Nie W, Wang X, Zhang J, Li T, Su L, Wang FS. Safety and immunological responses to human mesenchymal stem cell therapy in difficult-to-treat HIV-1-infected patients. Aids (London, England). 27: 1283-93. PMID 23925377 DOI: 10.1097/Qad.0B013E32835Fab77 |
0.425 |
|
| 2013 |
Bility MT, Li F, Cheng L, Su L. Liver immune-pathogenesis and therapy of human liver tropic virus infection in humanized mouse models. Journal of Gastroenterology and Hepatology. 28: 120-4. PMID 23855307 DOI: 10.1111/Jgh.12092 |
0.364 |
|
| 2013 |
Wang Y, Misumi I, Gu AD, Curtis TA, Su L, Whitmire JK, Wan YY. GATA-3 controls the maintenance and proliferation of T cells downstream of TCR and cytokine signaling. Nature Immunology. 14: 714-22. PMID 23708251 DOI: 10.1038/Ni.2623 |
0.459 |
|
| 2013 |
Liu SY, Aliyari R, Chikere K, Li G, Marsden MD, Smith JK, Pernet O, Guo H, Nusbaum R, Zack JA, Freiberg AN, Su L, Lee B, Cheng G. Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol. Immunity. 38: 92-105. PMID 23273844 DOI: 10.1016/J.Immuni.2012.11.005 |
0.434 |
|
| 2012 |
Bility MT, Zhang L, Washburn ML, Curtis TA, Kovalev GI, Su L. Generation of a humanized mouse model with both human immune system and liver cells to model hepatitis C virus infection and liver immunopathogenesis. Nature Protocols. 7: 1608-17. PMID 22899330 DOI: 10.1038/Nprot.2012.083 |
0.742 |
|
| 2012 |
Su L. Studying human immunology and immunopathology in humanized mice transplanted with human lymphoid tissues and immune cells. Cellular & Molecular Immunology. 9: 191-2. PMID 22565218 DOI: 10.1038/Cmi.2012.4 |
0.363 |
|
| 2012 |
Zhang L, Su L. HIV-1 immunopathogenesis in humanized mouse models. Cellular & Molecular Immunology. 9: 237-44. PMID 22504952 DOI: 10.1038/Cmi.2012.7 |
0.46 |
|
| 2011 |
Holmes D, Gao J, Su L. Foxp3 inhibits HDAC1 activity to modulate gene expression in human T cells. Virology. 421: 12-8. PMID 21974802 DOI: 10.1016/J.Virol.2011.09.002 |
0.75 |
|
| 2011 |
Hench VK, Su L. Regulation of IL-2 gene expression by Siva and FOXP3 in human T cells. Bmc Immunology. 12: 54. PMID 21955384 DOI: 10.1186/1471-2172-12-54 |
0.789 |
|
| 2011 |
Ding X, Yang W, Shi X, Du P, Su L, Qin Z, Chen J, Deng H. TNF receptor 1 mediates dendritic cell maturation and CD8 T cell response through two distinct mechanisms. Journal of Immunology (Baltimore, Md. : 1950). 187: 1184-91. PMID 21709152 DOI: 10.4049/Jimmunol.1002902 |
0.444 |
|
| 2011 |
Sivaraman V, Zhang L, Su L. Type I interferon contributes to CD4+ T cell depletion induced by infection with HIV-1 in the human thymus. Journal of Virology. 85: 9243-6. PMID 21697497 DOI: 10.1128/Jvi.00457-11 |
0.49 |
|
| 2011 |
Mackey-Cushman SL, Gao J, Holmes DA, Nunoya JI, Wang R, Unutmaz D, Su L. FoxP3 interacts with linker histone H1.5 to modulate gene expression and program Treg cell activity. Genes and Immunity. 12: 559-67. PMID 21654845 DOI: 10.1038/Gene.2011.31 |
0.712 |
|
| 2011 |
Zhang Z, Xu X, Lu J, Zhang S, Gu L, Fu J, Jin L, Li H, Zhao M, Zhang J, Wu H, Su L, Fu YX, Wang FS. B and T lymphocyte attenuator down-regulation by HIV-1 depends on type I interferon and contributes to T-cell hyperactivation. The Journal of Infectious Diseases. 203: 1668-78. PMID 21592997 DOI: 10.1093/Infdis/Jir165 |
0.537 |
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| 2011 |
Zhang L, Jiang Q, Li G, Jeffrey J, Kovalev GI, Su L. Efficient infection, activation, and impairment of pDCs in the BM and peripheral lymphoid organs during early HIV-1 infection in humanized rag2⁻/⁻γ C⁻/⁻ mice in vivo. Blood. 117: 6184-92. PMID 21505190 DOI: 10.1182/Blood-2011-01-331173 |
0.505 |
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| 2011 |
Cheng L, Wang J, Li X, Xing Q, Du P, Su L, Wang S. Interleukin-6 induces Gr-1+CD11b+ myeloid cells to suppress CD8+ T cell-mediated liver injury in mice. Plos One. 6: e17631. PMID 21394214 DOI: 10.1371/Journal.Pone.0017631 |
0.424 |
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| 2011 |
Washburn ML, Bility MT, Zhang L, Kovalev GI, Buntzman A, Frelinger JA, Barry W, Ploss A, Rice CM, Su L. A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease. Gastroenterology. 140: 1334-44. PMID 21237170 DOI: 10.1053/J.Gastro.2011.01.001 |
0.749 |
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| 2011 |
West JA, Gregory SM, Sivaraman V, Su L, Damania B. Activation of plasmacytoid dendritic cells by Kaposi's sarcoma-associated herpesvirus. Journal of Virology. 85: 895-904. PMID 20980519 DOI: 10.1128/Jvi.01007-10 |
0.382 |
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| 2010 |
Zhang LG, Meissner E, Chen JZ, Su LS. Current humanized mouse models for studying human immunology and HIV-1 immuno-pathogenesis Science China Life Sciences. 53: 195-203. PMID 20596827 DOI: 10.1007/S11427-010-0059-7 |
0.677 |
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| 2010 |
Johnson SM, Torrice CD, Bell JF, Monahan KB, Jiang Q, Wang Y, Ramsey MR, Jin J, Wong KK, Su L, Zhou D, Sharpless NE. Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition. The Journal of Clinical Investigation. 120: 2528-36. PMID 20577054 DOI: 10.1172/Jci41402 |
0.317 |
|
| 2010 |
Washburn ML, Kovalev GI, Koroleva E, Fu YX, Su L. LIGHT induces distinct signals to clear an AAV-expressed persistent antigen in the mouse liver and to induce liver inflammation. Plos One. 5: e10585. PMID 20498840 DOI: 10.1371/Journal.Pone.0010585 |
0.733 |
|
| 2010 |
Ince WL, Zhang L, Jiang Q, Arrildt K, Su L, Swanstrom R. Evolution of the HIV-1 env gene in the Rag2-/- gammaC-/- humanized mouse model. Journal of Virology. 84: 2740-52. PMID 20042504 DOI: 10.1128/Jvi.02180-09 |
0.452 |
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| 2009 |
Sivaraman V, Zhang L, Meissner EG, Jeffrey JL, Su L. The heptad repeat 2 domain is a major determinant for enhanced human immunodeficiency virus type 1 (HIV-1) fusion and pathogenicity of a highly pathogenic HIV-1 Env. Journal of Virology. 83: 11715-25. PMID 19726524 DOI: 10.1128/Jvi.00649-09 |
0.725 |
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| 2009 |
Choudhary SK, Rezk NL, Ince WL, Cheema M, Zhang L, Su L, Swanstrom R, Kashuba AD, Margolis DM. Suppression of human immunodeficiency virus type 1 (HIV-1) viremia with reverse transcriptase and integrase inhibitors, CD4+ T-cell recovery, and viral rebound upon interruption of therapy in a new model for HIV treatment in the humanized Rag2-/-{gamma}c-/- mouse. Journal of Virology. 83: 8254-8. PMID 19494021 DOI: 10.1128/Jvi.00580-09 |
0.496 |
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| 2008 |
Holmes D, Jiang Q, Zhang L, Su L. Foxp3 and Treg cells in HIV-1 infection and immuno-pathogenesis. Immunologic Research. 41: 248-66. PMID 18726715 DOI: 10.1007/S12026-008-8037-X |
0.746 |
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| 2008 |
Jiang Q, Zhang L, Wang R, Jeffrey J, Washburn ML, Brouwer D, Barbour S, Kovalev GI, Unutmaz D, Su L. FoxP3+CD4+ regulatory T cells play an important role in acute HIV-1 infection in humanized Rag2-/-gammaC-/- mice in vivo. Blood. 112: 2858-68. PMID 18544681 DOI: 10.1182/Blood-2008-03-145946 |
0.802 |
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| 2008 |
Lu X, Kovalev GI, Chang H, Kallin E, Knudsen G, Xia L, Mishra N, Ruiz P, Li E, Su L, Zhang Y. Inactivation of NuRD component Mta2 causes abnormal T cell activation and lupus-like autoimmune disease in mice. The Journal of Biological Chemistry. 283: 13825-33. PMID 18353770 DOI: 10.1074/Jbc.M801275200 |
0.411 |
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| 2007 |
Nordone SK, Ignacio GA, Su L, Sempowski GD, Golenbock DT, Li L, Dean GA. Failure of TLR4-driven NF-kappa B activation to stimulate virus replication in models of HIV type 1 activation. Aids Research and Human Retroviruses. 23: 1387-95. PMID 18184082 DOI: 10.1089/Aid.2007.0033 |
0.43 |
|
| 2007 |
Laakso MM, Lee FH, Haggarty B, Agrawal C, Nolan KM, Biscone M, Romano J, Jordan AP, Leslie GJ, Meissner EG, Su L, Hoxie JA, Doms RW. V3 loop truncations in HIV-1 envelope impart resistance to coreceptor inhibitors and enhanced sensitivity to neutralizing antibodies. Plos Pathogens. 3: e117. PMID 17722977 DOI: 10.1371/Journal.Ppat.0030117 |
0.683 |
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| 2007 |
Jiang Q, Coffield VM, Kondo M, Su L. TSLP is involved in expansion of early thymocyte progenitors. Bmc Immunology. 8: 11. PMID 17640367 DOI: 10.1186/1471-2172-8-11 |
0.794 |
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| 2007 |
Helms WS, Jeffrey JL, Holmes DA, Townsend MB, Clipstone NA, Su L. Modulation of NFAT-dependent gene expression by the RhoA signaling pathway in T cells. Journal of Leukocyte Biology. 82: 361-9. PMID 17502338 DOI: 10.1189/Jlb.0206120 |
0.805 |
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| 2007 |
Holmes D, Knudsen G, Mackey-Cushman S, Su L. FoxP3 enhances HIV-1 gene expression by modulating NFkappaB occupancy at the long terminal repeat in human T cells. The Journal of Biological Chemistry. 282: 15973-80. PMID 17416586 DOI: 10.1074/Jbc.M702051200 |
0.767 |
|
| 2007 |
Zhang L, Kovalev GI, Su L. HIV-1 infection and pathogenesis in a novel humanized mouse model. Blood. 109: 2978-81. PMID 17132723 DOI: 10.1182/Blood-2006-07-033159 |
0.503 |
|
| 2007 |
Su L. PD-1+ T cells: Exhausted and premature? Blood. 109: 4593-4594. DOI: 10.1182/Blood-2007-03-079434 |
0.429 |
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| 2006 |
Loomis RJ, Holmes DA, Elms A, Solski PA, Der CJ, Su L. Citron kinase, a RhoA effector, enhances HIV-1 virion production by modulating exocytosis. Traffic (Copenhagen, Denmark). 7: 1643-53. PMID 17118119 DOI: 10.1111/J.1600-0854.2006.00503.X |
0.784 |
|
| 2006 |
Meissner EG, Zhang L, Jiang S, Su L. Fusion-induced apoptosis contributes to thymocyte depletion by a pathogenic human immunodeficiency virus type 1 envelope in the human thymus. Journal of Virology. 80: 11019-30. PMID 16956934 DOI: 10.1128/Jvi.01382-06 |
0.728 |
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| 2006 |
Jiang Q, Su H, Knudsen G, Helms W, Su L. Delayed functional maturation of natural regulatory T cells in the medulla of postnatal thymus: role of TSLP. Bmc Immunology. 7: 6. PMID 16579866 DOI: 10.1186/1471-2172-7-6 |
0.718 |
|
| 2005 |
Williams KL, Lich JD, Duncan JA, Reed W, Rallabhandi P, Moore C, Kurtz S, Coffield VM, Accavitti-Loper MA, Su L, Vogel SN, Braunstein M, Ting JP. The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals. The Journal of Biological Chemistry. 280: 39914-24. PMID 16203735 DOI: 10.1074/Jbc.M502820200 |
0.77 |
|
| 2005 |
Wysocki CA, Jiang Q, Panoskaltsis-Mortari A, Taylor PA, McKinnon KP, Su L, Blazar BR, Serody JS. Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease. Blood. 106: 3300-7. PMID 16002422 DOI: 10.1182/Blood-2005-04-1632 |
0.41 |
|
| 2005 |
Meissner EG, Coffield VM, Su L. Thymic pathogenicity of an HIV-1 envelope is associated with increased CXCR4 binding efficiency and V5-gp41-dependent activity, but not V1/V2-associated CD4 binding efficiency and viral entry. Virology. 336: 184-97. PMID 15892960 DOI: 10.1016/J.Virol.2005.03.032 |
0.791 |
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| 2005 |
Okada Y, Feng Q, Lin Y, Jiang Q, Li Y, Coffield VM, Su L, Xu G, Zhang Y. hDOT1L links histone methylation to leukemogenesis. Cell. 121: 167-78. PMID 15851025 DOI: 10.1016/J.Cell.2005.05.021 |
0.752 |
|
| 2004 |
Coffield VM, Helms WS, Jiang Q, Su L. Galpha13 mediates a signal that is essential for proliferation and survival of thymocyte progenitors. The Journal of Experimental Medicine. 200: 1315-24. PMID 15534370 DOI: 10.1084/Jem.20040944 |
0.785 |
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| 2004 |
Meissner EG, Duus KM, Gao F, Yu XF, Su L. Characterization of a thymus-tropic HIV-1 isolate from a rapid progressor: role of the envelope. Virology. 328: 74-88. PMID 15380360 DOI: 10.1016/J.Virol.2004.07.019 |
0.697 |
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| 2003 |
Coffield VM, Su L. Receptor-ligand genetics: Inactivation of receptors with a modified viral protein. Discovery Medicine. 3: 30-2. PMID 20705033 |
0.761 |
|
| 2003 |
Meissner EG, Duus KM, Loomis R, D'Agostin R, Su L. HIV-1 replication and pathogenesis in the human thymus. Current Hiv Research. 1: 275-85. PMID 15046252 DOI: 10.2174/1570162033485258 |
0.797 |
|
| 2003 |
Gebuhr TC, Kovalev GI, Bultman S, Godfrey V, Su L, Magnuson T. The role of Brg1, a catalytic subunit of mammalian chromatin-remodeling complexes, in T cell development. The Journal of Experimental Medicine. 198: 1937-49. PMID 14676303 DOI: 10.1084/Jem.20030714 |
0.432 |
|
| 2003 |
Coffield VM, Jiang Q, Su L. A genetic approach to inactivating chemokine receptors using a modified viral protein. Nature Biotechnology. 21: 1321-7. PMID 14555957 DOI: 10.1038/Nbt889 |
0.779 |
|
| 2003 |
Miller ED, Smith JA, Lichtinger M, Wang L, Su L. Activation of the signal transducer and activator of transcription 1 signaling pathway in thymocytes from HIV-1-infected human thymus. Aids (London, England). 17: 1269-77. PMID 12799548 DOI: 10.1097/00002030-200306130-00001 |
0.457 |
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| 2002 |
Solski PA, Helms W, Keely PJ, Su L, Der CJ. RhoA biological activity is dependent on prenylation but independent of specific isoprenoid modification. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 13: 363-73. PMID 12193475 |
0.73 |
|
| 2001 |
Kao SM, Miller ED, Su L. A leucine zipper motif in the cytoplasmic domain of gp41 is required for HIV-1 replication and pathogenesis in vivo. Virology. 289: 208-17. PMID 11689043 DOI: 10.1006/Viro.2001.1112 |
0.442 |
|
| 2001 |
Kovalev GI, Franklin DS, Coffield VM, Xiong Y, Su L. An important role of CDK inhibitor p18(INK4c) in modulating antigen receptor-mediated T cell proliferation. Journal of Immunology (Baltimore, Md. : 1950). 167: 3285-92. PMID 11544316 DOI: 10.4049/Jimmunol.167.6.3285 |
0.793 |
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| 2001 |
Miller ED, Duus KM, Townsend M, Yi Y, Collman R, Reitz M, Su L. Human immunodeficiency virus type 1 IIIB selected for replication in vivo exhibits increased envelope glycoproteins in virions without alteration in coreceptor usage: Separation of in vivo replication from macrophage tropism Journal of Virology. 75: 8498-8506. PMID 11507195 DOI: 10.1128/Jvi.75.18.8498-8506.2001 |
0.44 |
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| 2001 |
Duus KM, Miller ED, Smith JA, Kovalev GI, Su L. Separation of human immunodeficiency virus type 1 replication from nef-mediated pathogenesis in the human thymus. Journal of Virology. 75: 3916-24. PMID 11264380 DOI: 10.1128/Jvi.75.8.3916-3924.2001 |
0.432 |
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| 2000 |
Wang L, Zhang H, Solski PA, Hart MJ, Der CJ, Su L. Modulation of HIV-1 replication by a novel RhoA effector activity. Journal of Immunology (Baltimore, Md. : 1950). 164: 5369-74. PMID 10799900 DOI: 10.4049/Jimmunol.164.10.5369 |
0.444 |
|
| 2000 |
Simon TD, Kovalev GI, Coffield VM, Su L. Regulation of the hematopoietic stem/progenitor cell subsets in mouse bone marrow by the cdk inhibitor p18INK4c Experimental Hematology. 28: 1494. DOI: 10.1016/S0301-472X(00)00567-1 |
0.769 |
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| 1999 |
Zhang H, Wang L, Kao S, Whitehead IP, Hart MJ, Liu B, Duus K, Burridge K, Der CJ, Su L. Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF. Current Biology : Cb. 9: 1271-4. PMID 10556093 DOI: 10.1016/S0960-9822(99)80511-9 |
0.447 |
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| 1997 |
Fultz PN, Su L, May P, West JT. Isolation of sooty mangabey simian T-cell leukemia virus type I [STLV-I(sm)] and characterization of a mangabey T-cell line coinfected with STLV-I(sm) and simian immunodeficiency virus SIVsmmPBj14. Virology. 235: 271-85. PMID 9281507 DOI: 10.1006/Viro.1997.8705 |
0.33 |
|
| 1997 |
Su L, Lee R, Bonyhadi M, Matsuzaki H, Forestell S, Escaich S, Böhnlein E, Kaneshima H. Hematopoietic Stem Cell–Based Gene Therapy for Acquired Immunodeficiency Syndrome: Efficient Transduction and Expression of RevM10 in Myeloid Cells In Vivo and In Vitro Blood. 89: 2283-2290. DOI: 10.1182/Blood.V89.7.2283 |
0.459 |
|
| 1997 |
Bonyhadi ML, Moss K, Voytovich A, Auten J, Kalfoglou C, Plavec I, Forestell S, Su L, Böhnlein E, Kaneshima H. RevM10-expressing T cells derived in vivo from transduced human hematopoietic stem-progenitor cells inhibit human immunodeficiency virus replication. Journal of Virology. 71: 4707-4716. DOI: 10.1128/Jvi.71.6.4707-4716.1997 |
0.536 |
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| 1997 |
Su L. HIV-1 pathogenesis and therapeutic intervention in the SCID-hu Thy/Liv mouse: A model for primary HIV-1 infection in the human thymus Reviews in Medical Virology. 7: 157-166. DOI: 10.1002/(SICI)1099-1654(199709)7:3<157::AID-RMV197>3.0.CO;2-R |
0.355 |
|
| 1995 |
Fultz PN, Schwiebert RS, Su L, Salter MM. Effects of total lymphoid irradiation on SIV-infected macaques Aids Research and Human Retroviruses. 11: 1517-1527. PMID 8679296 DOI: 10.1089/aid.1995.11.1517 |
0.311 |
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| 1995 |
Bonyhadi ML, Su L, Auten J, McCune JM, Kaneshima H. Development of a human thymic organ culture model for the study of HIV pathogenesis Aids Research and Human Retroviruses. 11: 1073-1080. PMID 8554904 |
0.333 |
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| 1994 |
Kaneshima H, Su L, Bonyhadi ML, Connor RI, Ho DD, Mccune JM. Rapid-high, syncytium-inducing isolates of human immunodeficiency virus type 1 induce cytopathicity in the human thymus of the SCID-hu mouse Journal of Virology. 68: 8188-8192. PMID 7966610 |
0.333 |
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