Year |
Citation |
Score |
2023 |
Xiao X, Feng J, Ma J, Xia X, Liu X, Zhang J, Ding C, Pang X, Zhang A. Design, Synthesis, and Pharmacological Evaluation of Multisubstituted Pyrido[4,3-]pyrimidine Analogues Bearing Deuterated Methylene Linkers as Potent KRAS Inhibitors. Journal of Medicinal Chemistry. PMID 37921024 DOI: 10.1021/acs.jmedchem.3c01724 |
0.309 |
|
2023 |
He P, Feng J, Xia X, Sun Y, He J, Guan T, Peng Y, Zhang X, Liu M, Pang X, Chen Y. Discovery of a Potent and Oral Available Complex I OXPHOS Inhibitor That Abrogates Tumor Growth and Circumvents MEKi Resistance. Journal of Medicinal Chemistry. PMID 37130350 DOI: 10.1021/acs.jmedchem.2c01844 |
0.335 |
|
2021 |
Guo J, Liu Y, Lv J, Zou B, Chen Z, Li K, Feng J, Cai Z, Wei L, Liu M, Pang X. BCL6 confers KRAS-mutant non-small-cell lung cancer resistance to BET inhibitors. The Journal of Clinical Investigation. 131. PMID 33393503 DOI: 10.1172/JCI133090 |
0.317 |
|
2019 |
Hu K, Li K, Lv J, Feng J, Chen J, Wu H, Cheng F, Jiang W, Wang J, Pei H, Chiao PJ, Cai Z, Chen Y, Liu M, Pang X. Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma. The Journal of Clinical Investigation. PMID 31874110 DOI: 10.1172/Jci124049 |
0.317 |
|
2019 |
Pang X, Yi Z, Zhang J, Lu B, Sung B, Qu W, Aggarwal BB, Liu M. Correction: Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway. Cancer Research. 79: 685. PMID 30709873 DOI: 10.1158/0008-5472.CAN-18-3859 |
0.493 |
|
2018 |
Jiang X, Lu W, Shen X, Wang Q, Lv J, Liu M, Cheng F, Zhao Z, Pang X. Repurposing sertraline sensitizes non-small cell lung cancer cells to erlotinib by inducing autophagy. Jci Insight. 3. PMID 29875309 DOI: 10.1172/Jci.Insight.98921 |
0.44 |
|
2017 |
Wu Z, Lu W, Yu W, Wang T, Li W, Liu G, Zhang H, Pang X, Huang J, Liu M, Cheng F, Tang Y. Quantitative and Systems Pharmacology 2. In silico polypharmacology of G protein-coupled receptor ligands via network-based approaches. Pharmacological Research. PMID 29133212 DOI: 10.1016/J.Phrs.2017.11.005 |
0.33 |
|
2016 |
Li K, Guo Q, Yang J, Chen H, Hu K, Zhao J, Zheng S, Pang X, Zhou S, Dang Y, Li L. FOXD3 is a tumor suppressor of colon cancer by inhibiting EGFR-Ras-Raf-MEK-ERK signal pathway. Oncotarget. PMID 27926503 DOI: 10.18632/oncotarget.13790 |
0.317 |
|
2016 |
Pang X, Liu M. A combination therapy for KRAS-mutant lung cancer by targeting synthetic lethal partners of mutant KRAS. Chinese Journal of Cancer. 35: 92. PMID 27793187 DOI: 10.1186/S40880-016-0154-7 |
0.462 |
|
2016 |
Pang X, Liu M. Defeat Mutant KRAS with Synthetic Lethality. Small Gtpases. 0. PMID 27463838 DOI: 10.1080/21541248.2016.1213783 |
0.412 |
|
2016 |
Chen J, Guo J, Chen Z, Wang J, Liu M, Pang X. Linifanib (ABT-869) Potentiates the Efficacy of Chemotherapeutic Agents through the Suppression of Receptor Tyrosine Kinase-Mediated AKT/mTOR Signaling Pathways in Gastric Cancer. Scientific Reports. 6: 29382. PMID 27387652 DOI: 10.1038/Srep29382 |
0.489 |
|
2016 |
Guo J, Lv J, Chang S, Chen Z, Lu W, Xu C, Liu M, Pang X. Inhibiting cytoplasmic accumulation of HuR synergizes genotoxic agents in urothelial carcinoma of the bladder. Oncotarget. PMID 27303922 DOI: 10.18632/Oncotarget.9932 |
0.461 |
|
2016 |
Wang J, Hu K, Guo J, Cheng F, Lv J, Jiang W, Lu W, Liu J, Pang X, Liu M. Suppression of KRas-mutant cancer through the combined inhibition of KRAS with PLK1 and ROCK. Nature Communications. 7: 11363. PMID 27193833 DOI: 10.1038/Ncomms11363 |
0.457 |
|
2016 |
Wu Y, Wang X, Chang S, Lu W, Liu M, Pang X. β-Lapachone Induces NQO1- and Oxidative Stress-Dependent Hsp90 Cleavage and Inhibits Tumor Growth and Angiogenesis. The Journal of Pharmacology and Experimental Therapeutics. PMID 27048660 DOI: 10.1124/Jpet.116.232694 |
0.444 |
|
2016 |
Rong JC, Liu M, Li Y, Sun TY, Pang XH, Qin QL, Chen XL, Xie BB. Complete genome sequence of a marine bacterium with two chromosomes, Pseudoalteromonas translucida KMM 520(T). Marine Genomics. PMID 26849967 DOI: 10.1016/j.margen.2016.01.007 |
0.444 |
|
2015 |
Jiao Y, Pang X, Liu M, Zhang B, Li L, Zhai G. Recent progresses in bioadhesive microspheres via transmucosal administration. Colloids and Surfaces. B, Biointerfaces. 140: 361-372. PMID 26774569 DOI: 10.1016/j.colsurfb.2015.12.049 |
0.317 |
|
2015 |
Li Z, Su H, Yu W, Li X, Cheng H, Liu M, Pang X, Zou X. Design, synthesis and anticancer activities of novel otobain derivatives. Organic & Biomolecular Chemistry. PMID 26593226 DOI: 10.1039/C5Ob02176F |
0.423 |
|
2015 |
Lv J, Wang J, Chang S, Liu M, Pang X. The greedy nature of mutant RAS: a boon for drug discovery targeting cancer metabolism? Acta Biochimica Et Biophysica Sinica. PMID 26487443 DOI: 10.1093/Abbs/Gmv102 |
0.4 |
|
2015 |
Guan Q, Liu M, Liu R, Zhang H, Pang X, Sun Y, Zeng D. Tongxinluo Induces nNOS Expression Through ERK Activation: Possible Contribution to the Effects of Tongxinluo to Attenuate Vasoconstriction. Journal of Cardiovascular Pharmacology. 66: 9-15. PMID 26164718 DOI: 10.1097/FJC.0000000000000228 |
0.365 |
|
2015 |
Li P, Liu Y, Wang H, He Y, Wang X, He Y, Lv F, Chen H, Pang X, Liu M, Shi T, Yi Z. PubAngioGen: a database and knowledge for angiogenesis and related diseases. Nucleic Acids Research. 43: D963-7. PMID 25392416 DOI: 10.1093/Nar/Gku1139 |
0.393 |
|
2015 |
Wang B, Yu W, Guo J, Jiang X, Lu W, Liu M, Pang X. The antiparasitic drug, potassium antimony tartrate, inhibits tumor angiogenesis and tumor growth in nonsmall-cell lung cancer. The Journal of Pharmacology and Experimental Therapeutics. 352: 129-38. PMID 25352499 DOI: 10.1124/Jpet.114.218644 |
0.526 |
|
2014 |
Yang F, Zhang T, Wu H, Yang Y, Liu N, Chen A, Li Q, Li J, Qin L, Jiang B, Wang X, Pang X, Yi Z, Liu M, Chen Y. Design and optimization of novel hydroxamate-based histone deacetylase inhibitors of Bis-substituted aromatic amides bearing potent activities against tumor growth and metastasis. Journal of Medicinal Chemistry. 57: 9357-69. PMID 25360834 DOI: 10.1021/Jm5012148 |
0.49 |
|
2014 |
Wang J, Zhang L, Chen G, Zhang J, Li Z, Lu W, Liu M, Pang X. Small molecule 1'-acetoxychavicol acetate suppresses breast tumor metastasis by regulating the SHP-1/STAT3/MMPs signaling pathway. Breast Cancer Research and Treatment. 148: 279-89. PMID 25301089 DOI: 10.1007/S10549-014-3165-6 |
0.474 |
|
2014 |
Kong L, Rao M, Ou J, Yin J, Lu W, Liu M, Pang X, Gao S. Total synthesis and biological studies of cryptocin and derivatives of equisetin and fusarisetin A. Organic & Biomolecular Chemistry. 12: 7591-7. PMID 25139438 DOI: 10.1039/C4Ob01149J |
0.372 |
|
2014 |
Zheng C, Fang Y, Tong W, Li G, Wu H, Zhou W, Lin Q, Yang F, Yang Z, Wang P, Peng Y, Pang X, Yi Z, Luo J, Liu M, et al. Synthesis and biological evaluation of novel tetrahydro-β-carboline derivatives as antitumor growth and metastasis agents through inhibiting the transforming growth factor-β signaling pathway. Journal of Medicinal Chemistry. 57: 600-12. PMID 24417479 DOI: 10.1021/Jm401117T |
0.466 |
|
2012 |
Dai F, Chen Y, Song Y, Huang L, Zhai D, Dong Y, Lai L, Zhang T, Li D, Pang X, Liu M, Yi Z. A natural small molecule harmine inhibits angiogenesis and suppresses tumour growth through activation of p53 in endothelial cells. Plos One. 7: e52162. PMID 23300602 DOI: 10.1371/Journal.Pone.0052162 |
0.511 |
|
2012 |
Pang X, Liu M, Bi F. [Review on the research progress of the role of miRNAs in gastric cancer]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi = Journal of Biomedical Engineering = Shengwu Yixue Gongchengxue Zazhi. 29: 780-3, 802. PMID 23016435 |
0.318 |
|
2012 |
Chen J, Wang J, Lin L, He L, Wu Y, Zhang L, Yi Z, Chen Y, Pang X, Liu M. Inhibition of STAT3 signaling pathway by nitidine chloride suppressed the angiogenesis and growth of human gastric cancer. Molecular Cancer Therapeutics. 11: 277-87. PMID 22203730 DOI: 10.1158/1535-7163.Mct-11-0648 |
0.53 |
|
2012 |
Wang Y, Chen Y, Wang J, Chen J, Aggarwal BB, Pang X, Liu M. Xanthohumol, a prenylated chalcone derived from hops, suppresses cancer cell invasion through inhibiting the expression of CXCR4 chemokine receptor. Current Molecular Medicine. 12: 153-62. PMID 22172099 DOI: 10.2174/156652412798889072 |
0.492 |
|
2011 |
Chen J, Li T, Wu Y, He L, Zhang L, Shi T, Yi Z, Liu M, Pang X. Prognostic significance of vascular endothelial growth factor expression in gastric carcinoma: a meta-analysis. Journal of Cancer Research and Clinical Oncology. 137: 1799-812. PMID 21918901 DOI: 10.1007/S00432-011-1057-2 |
0.371 |
|
2011 |
Wu Y, He L, Zhang L, Chen J, Yi Z, Zhang J, Liu M, Pang X. Anacardic acid (6-pentadecylsalicylic acid) inhibits tumor angiogenesis by targeting Src/FAK/Rho GTPases signaling pathway. The Journal of Pharmacology and Experimental Therapeutics. 339: 403-11. PMID 21828260 DOI: 10.1124/Jpet.111.181891 |
0.495 |
|
2011 |
Zhou Q, Zhai Y, Lou J, Liu M, Pang X, Sun F. Thiabendazole inhibits ubiquinone reduction activity of mitochondrial respiratory complex II via a water molecule mediated binding feature. Protein & Cell. 2: 531-42. PMID 21822798 DOI: 10.1007/S13238-011-1079-1 |
0.328 |
|
2011 |
Pang X, Zhang L, Lai L, Chen J, Wu Y, Yi Z, Zhang J, Qu W, Aggarwal BB, Liu M. 1'-Acetoxychavicol acetate suppresses angiogenesis-mediated human prostate tumor growth by targeting VEGF-mediated Src-FAK-Rho GTPase-signaling pathway. Carcinogenesis. 32: 904-12. PMID 21427164 DOI: 10.1093/Carcin/Bgr052 |
0.532 |
|
2011 |
Pang X, Wu Y, Wu Y, Lu B, Chen J, Wang J, Yi Z, Qu W, Liu M. (-)-Gossypol suppresses the growth of human prostate cancer xenografts via modulating VEGF signaling-mediated angiogenesis. Molecular Cancer Therapeutics. 10: 795-805. PMID 21372225 DOI: 10.1158/1535-7163.MCT-10-0936 |
0.53 |
|
2011 |
He L, Wu Y, Lin L, Wang J, Wu Y, Chen Y, Yi Z, Liu M, Pang X. Hispidulin, a small flavonoid molecule, suppresses the angiogenesis and growth of human pancreatic cancer by targeting vascular endothelial growth factor receptor 2-mediated PI3K/Akt/mTOR signaling pathway. Cancer Science. 102: 219-25. PMID 21087351 DOI: 10.1111/J.1349-7006.2010.01778.X |
0.541 |
|
2010 |
Dong Y, Lu B, Zhang X, Zhang J, Lai L, Li D, Wu Y, Song Y, Luo J, Pang X, Yi Z, Liu M. Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway. Carcinogenesis. 31: 2097-104. PMID 20732905 DOI: 10.1093/Carcin/Bgq167 |
0.538 |
|
2010 |
Pang X, Zhang L, Wu Y, Lin L, Li J, Qu W, Safe S, Liu M. Methyl 2-cyano-3,11-dioxo-18-olean-1,12-dien-30-oate (CDODA-Me), a derivative of glycyrrhetinic acid, functions as a potent angiogenesis inhibitor. The Journal of Pharmacology and Experimental Therapeutics. 335: 172-9. PMID 20631299 DOI: 10.1124/Jpet.110.171066 |
0.522 |
|
2010 |
Liu M, Dong F, Yan X, Zeng W, Hou L, Pang X. Biosorption of uranium by Saccharomyces cerevisiae and surface interactions under culture conditions. Bioresource Technology. 101: 8573-80. PMID 20599379 DOI: 10.1016/j.biortech.2010.06.063 |
0.319 |
|
2010 |
Pang X, Yi Z, Zhang J, Lu B, Sung B, Qu W, Aggarwal BB, Liu M. Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway. Cancer Research. 70: 1951-9. PMID 20160026 DOI: 10.1158/0008-5472.Can-09-3201 |
0.56 |
|
2009 |
Cho SG, Yi Z, Pang X, Yi T, Wang Y, Luo J, Wu Z, Li D, Liu M. Kisspeptin-10, a KISS1-derived decapeptide, inhibits tumor angiogenesis by suppressing Sp1-mediated VEGF expression and FAK/Rho GTPase activation Cancer Research. 69: 7062-7070. PMID 19671799 DOI: 10.1158/0008-5472.Can-09-0476 |
0.545 |
|
2009 |
Pang X, Yi Z, Zhang X, Sung B, Qu W, Lian X, Aggarwal BB, Liu M. Acetyl-11-keto-beta-boswellic acid inhibits prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis. Cancer Research. 69: 5893-900. PMID 19567671 DOI: 10.1158/0008-5472.Can-09-0755 |
0.534 |
|
2009 |
Pang X, Yi T, Yi Z, Cho SG, Qu W, Pinkaew D, Fujise K, Liu M. Morelloflavone, a biflavonoid, inhibits tumor angiogenesis by targeting rho GTPases and extracellular signal-regulated kinase signaling pathways. Cancer Research. 69: 518-25. PMID 19147565 DOI: 10.1158/0008-5472.Can-08-2531 |
0.559 |
|
2008 |
Yi T, Cho SG, Yi Z, Pang X, Rodriguez M, Wang Y, Sethi G, Aggarwal BB, Liu M. Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways. Molecular Cancer Therapeutics. 7: 1789-96. PMID 18644991 DOI: 10.1158/1535-7163.Mct-08-0124 |
0.559 |
|
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