Year |
Citation |
Score |
2023 |
Stroik S, Carvajal-Garcia J, Gupta D, Edwards A, Luthman A, Wyatt DW, Dannenberg RL, Feng W, Kunkel TA, Gupta GP, Hedglin M, Wood R, Doublié S, Rothenberg E, Ramsden DA. Stepwise requirements for polymerases δ and θ in theta-mediated end joining. Nature. 623: 836-841. PMID 37968395 DOI: 10.1038/s41586-023-06729-7 |
0.579 |
|
2023 |
Stroik S, Luthman AJ, Ramsden DA. Templated insertions-DNA repair gets acrobatic. Environmental and Molecular Mutagenesis. PMID 37438951 DOI: 10.1002/em.22564 |
0.509 |
|
2023 |
Yang F, Su W, Chung OW, Tracy L, Wang L, Ramsden DA, Zhang ZZZ. Retrotransposons hijack alt-EJ for DNA replication and eccDNA biogenesis. Nature. PMID 37438532 DOI: 10.1038/s41586-023-06327-7 |
0.552 |
|
2022 |
Luedeman ME, Stroik S, Feng W, Luthman AJ, Gupta GP, Ramsden DA. Poly(ADP) ribose polymerase promotes DNA polymerase theta-mediated end joining by activation of end resection. Nature Communications. 13: 4547. PMID 35927262 DOI: 10.1038/s41467-022-32166-7 |
0.539 |
|
2022 |
Kaminski AM, Chiruvella KK, Ramsden DA, Bebenek K, Kunkel TA, Pedersen LC. Analysis of diverse double-strand break synapsis with Polλ reveals basis for unique substrate specificity in nonhomologous end-joining. Nature Communications. 13: 3806. PMID 35778389 DOI: 10.1038/s41467-022-31278-4 |
0.539 |
|
2021 |
Ramsden DA, Carvajal-Garcia J, Gupta GP. Mechanism, cellular functions and cancer roles of polymerase-theta-mediated DNA end joining. Nature Reviews. Molecular Cell Biology. PMID 34522048 DOI: 10.1038/s41580-021-00405-2 |
0.488 |
|
2021 |
Feng W, Simpson DA, Cho JE, Carvajal-Garcia J, Smith CM, Headley KM, Hathaway N, Ramsden DA, Gupta GP. Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks. Nucleic Acids Research. PMID 33963863 DOI: 10.1093/nar/gkab299 |
0.486 |
|
2021 |
Carvajal-Garcia J, Crown KN, Ramsden DA, Sekelsky J. DNA polymerase theta suppresses mitotic crossing over. Plos Genetics. 17: e1009267. PMID 33750946 DOI: 10.1371/journal.pgen.1009267 |
0.544 |
|
2020 |
Kumar RJ, Chao HX, Simpson DA, Feng W, Cho MG, Roberts VR, Sullivan AR, Shah SJ, Wozny AS, Fagan-Solis K, Kumar S, Luthman A, Ramsden DA, Purvis JE, Gupta GP. Dual inhibition of DNA-PK and DNA polymerase theta overcomes radiation resistance induced by p53 deficiency. Nar Cancer. 2: zcaa038. PMID 33385162 DOI: 10.1093/narcan/zcaa038 |
0.476 |
|
2020 |
Zhao B, Rothenberg E, Ramsden DA, Lieber MR. The molecular basis and disease relevance of non-homologous DNA end joining. Nature Reviews. Molecular Cell Biology. PMID 33077885 DOI: 10.1038/s41580-020-00297-8 |
0.571 |
|
2020 |
Kaminski AM, Pryor JM, Ramsden DA, Kunkel TA, Pedersen LC, Bebenek K. Structural snapshots of human DNA polymerase μ engaged on a DNA double-strand break. Nature Communications. 11: 4784. PMID 32963245 DOI: 10.1038/s41467-020-18506-5 |
0.601 |
|
2020 |
Carvajal-Garcia J, Cho JE, Carvajal-Garcia P, Feng W, Wood RD, Sekelsky J, Gupta GP, Roberts SA, Ramsden DA. Mechanistic basis for microhomology identification and genome scarring by polymerase theta. Proceedings of the National Academy of Sciences of the United States of America. PMID 32234782 DOI: 10.1073/Pnas.1921791117 |
0.555 |
|
2020 |
Quiñones JL, Thapar U, Wilson SH, Ramsden DA, Demple B. Oxidative DNA-protein crosslinks formed in mammalian cells by abasic site lyases involved in DNA repair. Dna Repair. 87: 102773. PMID 31945542 DOI: 10.1016/J.Dnarep.2019.102773 |
0.534 |
|
2020 |
Carvajal-Garcia J, Gales ER, Ramsden DA, Sekelsky J. The Ortholog of RFWD3 Functions Independently of RAD51 During DNA Repair. G3 (Bethesda, Md.). PMID 31900333 DOI: 10.1534/g3.119.400903 |
0.452 |
|
2019 |
Feng W, Simpson DA, Carvajal-Garcia J, Price BA, Kumar RJ, Mose LE, Wood RD, Rashid N, Purvis JE, Parker JS, Ramsden DA, Gupta GP. Genetic determinants of cellular addiction to DNA polymerase theta. Nature Communications. 10: 4286. PMID 31537809 DOI: 10.1038/S41467-019-12234-1 |
0.56 |
|
2019 |
Kaminski AM, Chiruvella KK, Ramsden DA, Kunkel TA, Bebenek K, Pedersen LC. Unexpected behavior of DNA polymerase Mu opposite template 8-oxo-7,8-dihydro-2'-guanosine. Nucleic Acids Research. PMID 31435651 DOI: 10.2210/Pdb6P1R/Pdb |
0.654 |
|
2018 |
Pryor JM, Conlin MP, Carvajal-Garcia J, Luedeman ME, Luthman AJ, Small GW, Ramsden DA. Ribonucleotide incorporation enables repair of chromosome breaks by nonhomologous end joining. Science (New York, N.Y.). 361: 1126-1129. PMID 30213916 DOI: 10.1126/Science.Aat2477 |
0.566 |
|
2018 |
Brown AJ, Al-Soodani AT, Saul M, Her S, Garcia JC, Ramsden DA, Her C, Roberts SA. High-Throughput Analysis of DNA Break-Induced Chromosome Rearrangements by Amplicon Sequencing. Methods in Enzymology. 601: 111-144. PMID 29523230 DOI: 10.1016/Bs.Mie.2017.11.028 |
0.442 |
|
2017 |
Sastre-Moreno G, Pryor JM, Díaz-Talavera A, Ruiz JF, Ramsden DA, Blanco L. Polμ tumor variants decrease the efficiency and accuracy of NHEJ. Nucleic Acids Research. 45: 10018-10031. PMID 28973441 DOI: 10.1093/Nar/Gkx625 |
0.526 |
|
2017 |
Conlin MP, Reid DA, Small GW, Chang HH, Watanabe G, Lieber MR, Ramsden DA, Rothenberg E. DNA Ligase IV Guides End-Processing Choice during Nonhomologous End Joining. Cell Reports. 20: 2810-2819. PMID 28930678 DOI: 10.1016/J.Celrep.2017.08.091 |
0.625 |
|
2017 |
Moon AF, Pryor JM, Ramsden DA, Kunkel TA, Bebenek K, Pedersen LC. Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu. Nucleic Acids Research. 45: 9138-9148. PMID 28911097 DOI: 10.1093/Nar/Gkx527 |
0.653 |
|
2017 |
Yang Y, Gao Y, Mutter-Rottmayer L, Zlatanou A, Durando M, Ding W, Wyatt D, Ramsden D, Tanoue Y, Tateishi S, Vaziri C. DNA repair factor RAD18 and DNA polymerase Polκ confer tolerance of oncogenic DNA replication stress. The Journal of Cell Biology. PMID 28835467 DOI: 10.1083/Jcb.201702006 |
0.604 |
|
2017 |
Bellendir SP, Rognstad DJ, Morris LP, Zapotoczny G, Walton WG, Redinbo MR, Ramsden DA, Sekelsky J, Erie DA. Substrate preference of Gen endonucleases highlights the importance of branched structures as DNA damage repair intermediates. Nucleic Acids Research. PMID 28369583 DOI: 10.1093/Nar/Gkx214 |
0.363 |
|
2017 |
Sastre-Moreno G, Pryor JM, Moreno-Oñate M, Herrero-Ruiz AM, Cortés-Ledesma F, Blanco L, Ramsden DA, Ruiz JF. Regulation of human polλ by ATM-mediated phosphorylation during non-homologous end joining. Dna Repair. PMID 28109743 DOI: 10.1016/J.Dnarep.2017.01.004 |
0.609 |
|
2016 |
Reid DA, Conlin MP, Yin Y, Chang HH, Watanabe G, Lieber MR, Ramsden DA, Rothenberg E. Bridging of double-stranded breaks by the nonhomologous end-joining ligation complex is modulated by DNA end chemistry. Nucleic Acids Research. PMID 27924007 DOI: 10.1093/Nar/Gkw1221 |
0.643 |
|
2016 |
Wyatt DW, Feng W, Conlin MP, Yousefzadeh MJ, Roberts SA, Mieczkowski P, Wood RD, Gupta GP, Ramsden DA. Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks. Molecular Cell. PMID 27453047 DOI: 10.1016/J.Molcel.2016.06.020 |
0.58 |
|
2016 |
Schellenberg MJ, Perera L, Strom CN, Waters CA, Monian B, Appel CD, Vilas CK, Williams JG, Ramsden DA, Williams RS. Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2. Nucleic Acids Research. PMID 27060144 DOI: 10.1093/Nar/Gkw228 |
0.62 |
|
2016 |
Almohaini M, Chalasani SL, Bafail D, Akopiants K, Zhou T, Yannone SM, Ramsden DA, Hartman MC, Povirk LF. Nonhomologous end joining of complex DNA double-strand breaks with proximal thymine glycol and interplay with base excision repair. Dna Repair. 41: 16-26. PMID 27049455 DOI: 10.1016/J.Dnarep.2016.03.003 |
0.597 |
|
2015 |
Pryor JM, Waters CA, Aza A, Asagoshi K, Strom C, Mieczkowski PA, Blanco L, Ramsden DA. Essential role for polymerase specialization in cellular nonhomologous end joining. Proceedings of the National Academy of Sciences of the United States of America. 112: E4537-45. PMID 26240371 DOI: 10.1073/Pnas.1505805112 |
0.67 |
|
2015 |
Wilson JE, Petrucelli AS, Chen L, Koblansky AA, Truax AD, Oyama Y, Rogers AB, Brickey WJ, Wang Y, Schneider M, Mühlbauer M, Chou WC, Barker BR, Jobin C, Allbritton NL, ... Ramsden DA, et al. Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt. Nature Medicine. PMID 26107252 DOI: 10.1038/Nm.3908 |
0.383 |
|
2015 |
Reid DA, Keegan S, Leo-Macias A, Watanabe G, Strande NT, Chang HH, Oksuz BA, Fenyo D, Lieber MR, Ramsden DA, Rothenberg E. Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair. Proceedings of the National Academy of Sciences of the United States of America. 112: E2575-84. PMID 25941401 DOI: 10.1073/Pnas.1420115112 |
0.805 |
|
2015 |
Pryor JM, Waters CA, Aza A, Asagoshi K, Strom C, Mieczkowski PA, Blanco L, Ramsden DA. Essential role for polymerase specialization in cellular nonhomologous end joining Proceedings of the National Academy of Sciences of the United States of America. 112: E4537-E4545. DOI: 10.1073/pnas.1505805112 |
0.325 |
|
2014 |
Yousefzadeh MJ, Wyatt DW, Takata K, Mu Y, Hensley SC, Tomida J, Bylund GO, Doublié S, Johansson E, Ramsden DA, McBride KM, Wood RD. Mechanism of suppression of chromosomal instability by DNA polymerase POLQ. Plos Genetics. 10: e1004654. PMID 25275444 DOI: 10.1371/Journal.Pgen.1004654 |
0.667 |
|
2014 |
Strande NT, Carvajal-Garcia J, Hallett RA, Waters CA, Roberts SA, Strom C, Kuhlman B, Ramsden DA. Requirements for 5'dRP/AP lyase activity in Ku. Nucleic Acids Research. 42: 11136-43. PMID 25200085 DOI: 10.1093/Nar/Gku796 |
0.698 |
|
2014 |
Waters CA, Strande NT, Pryor JM, Strom CN, Mieczkowski P, Burkhalter MD, Oh S, Qaqish BF, Moore DT, Hendrickson EA, Ramsden DA. The fidelity of the ligation step determines how ends are resolved during nonhomologous end joining. Nature Communications. 5: 4286. PMID 24989324 DOI: 10.1038/Ncomms5286 |
0.731 |
|
2014 |
Williams GJ, Hammel M, Radhakrishnan SK, Ramsden D, Lees-Miller SP, Tainer JA. Structural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time. Dna Repair. 17: 110-20. PMID 24656613 DOI: 10.1016/J.Dnarep.2014.02.009 |
0.65 |
|
2014 |
Waters CA, Strande NT, Wyatt DW, Pryor JM, Ramsden DA. Nonhomologous end joining: a good solution for bad ends. Dna Repair. 17: 39-51. PMID 24630899 DOI: 10.1016/J.Dnarep.2014.02.008 |
0.778 |
|
2014 |
Moon AF, Pryor JM, Ramsden DA, Kunkel TA, Bebenek K, Pedersen LC. Sustained active site rigidity during synthesis by human DNA polymerase μ. Nature Structural & Molecular Biology. 21: 253-60. PMID 24487959 DOI: 10.1038/Nsmb.2766 |
0.645 |
|
2014 |
Kusumoto-Matsuo R, Ghosh D, Karmakar P, May A, Ramsden D, Bohr VA. Serines 440 and 467 in the Werner syndrome protein are phosphorylated by DNA-PK and affects its dynamics in response to DNA double strand breaks. Aging. 6: 70-81. PMID 24429382 DOI: 10.18632/AGING.100629 |
0.508 |
|
2013 |
Mohapatra S, Yannone SM, Lee SH, Hromas RA, Akopiants K, Menon V, Ramsden DA, Povirk LF. Trimming of damaged 3' overhangs of DNA double-strand breaks by the Metnase and Artemis endonucleases. Dna Repair. 12: 422-32. PMID 23602515 DOI: 10.1016/J.Dnarep.2013.03.005 |
0.666 |
|
2012 |
Strande NT, Waters CA, Ramsden DA. Resolution of complex ends by Nonhomologous end joining - better to be lucky than good? Genome Integrity. 3: 10. PMID 23276302 DOI: 10.1186/2041-9414-3-10 |
0.739 |
|
2012 |
Schellenberg MJ, Appel CD, Adhikari S, Robertson PD, Ramsden DA, Williams RS. Mechanism of repair of 5'-topoisomerase II-DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2. Nature Structural & Molecular Biology. 19: 1363-71. PMID 23104055 DOI: 10.1038/Nsmb.2418 |
0.632 |
|
2012 |
Ramsden DA, Asagoshi K. DNA polymerases in nonhomologous end joining: are there any benefits to standing out from the crowd? Environmental and Molecular Mutagenesis. 53: 741-51. PMID 22987211 DOI: 10.1002/Em.21725 |
0.681 |
|
2012 |
Strande N, Roberts SA, Oh S, Hendrickson EA, Ramsden DA. Specificity of the dRP/AP lyase of Ku promotes nonhomologous end joining (NHEJ) fidelity at damaged ends. The Journal of Biological Chemistry. 287: 13686-93. PMID 22362780 DOI: 10.1074/Jbc.M111.329730 |
0.757 |
|
2011 |
Ramsden DA. Polymerases in nonhomologous end joining: building a bridge over broken chromosomes. Antioxidants & Redox Signaling. 14: 2509-19. PMID 20649463 DOI: 10.1089/Ars.2010.3429 |
0.674 |
|
2010 |
Mani RS, Yu Y, Fang S, Lu M, Fanta M, Zolner AE, Tahbaz N, Ramsden DA, Litchfield DW, Lees-Miller SP, Weinfeld M. Dual modes of interaction between XRCC4 and polynucleotide kinase/phosphatase: implications for nonhomologous end joining. The Journal of Biological Chemistry. 285: 37619-29. PMID 20852255 DOI: 10.1074/Jbc.M109.058719 |
0.427 |
|
2010 |
Ramsden DA, Weed BD, Reddy YV. V(D)J recombination: Born to be wild. Seminars in Cancer Biology. 20: 254-60. PMID 20600921 DOI: 10.1016/J.Semcancer.2010.06.002 |
0.307 |
|
2010 |
Kusumoto-Matsuo R, Opresko PL, Ramsden D, Tahara H, Bohr VA. Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops. Aging. 2: 274-84. PMID 20519774 DOI: v2/n5/full/100141.html |
0.582 |
|
2010 |
Roberts SA, Strande N, Burkhalter MD, Strom C, Havener JM, Hasty P, Ramsden DA. Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends. Nature. 464: 1214-7. PMID 20383123 DOI: 10.1038/Nature08926 |
0.805 |
|
2009 |
Burkhalter MD, Roberts SA, Havener JM, Ramsden DA. Activity of ribonucleotide reductase helps determine how cells repair DNA double strand breaks. Dna Repair. 8: 1258-63. PMID 19713159 DOI: 10.1016/J.Dnarep.2009.07.009 |
0.513 |
|
2009 |
Garcia-Diaz M, Bebenek K, Larrea AA, Havener JM, Perera L, Krahn JM, Pedersen LC, Ramsden DA, Kunkel TA. Template strand scrunching during DNA gap repair synthesis by human polymerase lambda. Nature Structural & Molecular Biology. 16: 967-72. PMID 19701199 DOI: 10.1038/Nsmb.1654 |
0.608 |
|
2009 |
Zhou T, Akopiants K, Mohapatra S, Lin PS, Valerie K, Ramsden DA, Lees-Miller SP, Povirk LF. Tyrosyl-DNA phosphodiesterase and the repair of 3'-phosphoglycolate-terminated DNA double-strand breaks. Dna Repair. 8: 901-11. PMID 19505854 DOI: 10.1016/J.Dnarep.2009.05.003 |
0.67 |
|
2008 |
Bukowy Z, Harrigan JA, Ramsden DA, Tudek B, Bohr VA, Stevnsner T. WRN Exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either DNA strand Nucleic Acids Research. 36: 4975-4987. PMID 18658245 DOI: 10.1093/Nar/Gkn468 |
0.496 |
|
2008 |
Mueller GA, Moon AF, Derose EF, Havener JM, Ramsden DA, Pedersen LC, London RE. A comparison of BRCT domains involved in nonhomologous end-joining: introducing the solution structure of the BRCT domain of polymerase lambda. Dna Repair. 7: 1340-51. PMID 18585102 DOI: 10.1016/J.Dnarep.2008.04.018 |
0.56 |
|
2008 |
Kusumoto R, Dawut L, Marchetti C, Wan Lee J, Vindigni A, Ramsden D, Bohr VA. Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing. Biochemistry. 47: 7548-56. PMID 18558713 DOI: 10.1021/bi702325t |
0.567 |
|
2008 |
Davis BJ, Havener JM, Ramsden DA. End-bridging is required for pol mu to efficiently promote repair of noncomplementary ends by nonhomologous end joining. Nucleic Acids Research. 36: 3085-94. PMID 18397950 DOI: 10.1093/Nar/Gkn164 |
0.63 |
|
2007 |
DeRose EF, Clarkson MW, Gilmore SA, Galban CJ, Tripathy A, Havener JM, Mueller GA, Ramsden DA, London RE, Lee AL. Solution structure of polymerase mu's BRCT Domain reveals an element essential for its role in nonhomologous end joining. Biochemistry. 46: 12100-10. PMID 17915942 DOI: 10.1021/Bi7007728 |
0.36 |
|
2007 |
Povirk LF, Zhou RZ, Ramsden DA, Lees-Miller SP, Valerie K. Phosphorylation in the serine/threonine 2609-2647 cluster promotes but is not essential for DNA-dependent protein kinase-mediated nonhomologous end joining in human whole-cell extracts. Nucleic Acids Research. 35: 3869-78. PMID 17526517 DOI: 10.1093/Nar/Gkm339 |
0.584 |
|
2007 |
Roberts SA, Ramsden DA. Loading of the nonhomologous end joining factor, Ku, on protein-occluded DNA ends. The Journal of Biological Chemistry. 282: 10605-13. PMID 17289670 DOI: 10.1074/Jbc.M611125200 |
0.625 |
|
2007 |
Moon AF, Garcia-Diaz M, Bebenek K, Davis BJ, Zhong X, Ramsden DA, Kunkel TA, Pedersen LC. Structural insight into the substrate specificity of DNA Polymerase mu. Nature Structural & Molecular Biology. 14: 45-53. PMID 17159995 DOI: 10.1038/Nsmb1180 |
0.601 |
|
2007 |
Moon AF, Garcia-Diaz M, Bebenek K, Davis BJ, Zhong X, Ramsden DA, Kunkel TA, Pedersen LC. Erratum: Corrigendum: Structural insight into the substrate specificity of DNA Polymerase μ Nature Structural & Molecular Biology. 14: 680-680. DOI: 10.1038/Nsmb0707-680B |
0.563 |
|
2006 |
Juárez R, Ruiz JF, Nick McElhinny SA, Ramsden D, Blanco L. A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis. Nucleic Acids Research. 34: 4572-82. PMID 16963491 DOI: 10.1093/Nar/Gkl457 |
0.809 |
|
2006 |
Reddy YV, Perkins EJ, Ramsden DA. Genomic instability due to V(D)J recombination-associated transposition. Genes & Development. 20: 1575-82. PMID 16778076 DOI: 10.1101/gad.1432706 |
0.54 |
|
2005 |
Nick McElhinny SA, Havener JM, Garcia-Diaz M, Juárez R, Bebenek K, Kee BL, Blanco L, Kunkel TA, Ramsden DA. A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining. Molecular Cell. 19: 357-66. PMID 16061182 DOI: 10.1016/J.Molcel.2005.06.012 |
0.801 |
|
2004 |
Reddy YV, Ding Q, Lees-Miller SP, Meek K, Ramsden DA. Non-homologous end joining requires that the DNA-PK complex undergo an autophosphorylation-dependent rearrangement at DNA ends. The Journal of Biological Chemistry. 279: 39408-13. PMID 15258142 DOI: 10.1074/Jbc.M406432200 |
0.65 |
|
2004 |
Nick McElhinny SA, Ramsden DA. Sibling rivalry: competition between Pol X family members in V(D)J recombination and general double strand break repair. Immunological Reviews. 200: 156-64. PMID 15242403 DOI: 10.1111/J.0105-2896.2004.00160.X |
0.793 |
|
2004 |
Meek K, Gupta S, Ramsden DA, Lees-Miller SP. The DNA-dependent protein kinase: the director at the end. Immunological Reviews. 200: 132-41. PMID 15242401 DOI: 10.1111/J.0105-2896.2004.00162.X |
0.669 |
|
2004 |
Cowell LG, Davila M, Ramsden D, Kelsoe G. Computational tools for understanding sequence variability in recombination signals. Immunological Reviews. 200: 57-69. PMID 15242396 DOI: 10.1111/J.0105-2896.2004.00171.X |
0.302 |
|
2004 |
Perkins EJ, Kee BL, Ramsden DA. Histone 3 lysine 4 methylation during the pre-B to immature B-cell transition. Nucleic Acids Research. 32: 1942-7. PMID 15051812 DOI: 10.1093/Nar/Gkh523 |
0.459 |
|
2003 |
Ding Q, Reddy YV, Wang W, Woods T, Douglas P, Ramsden DA, Lees-Miller SP, Meek K. Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair. Molecular and Cellular Biology. 23: 5836-48. PMID 12897153 DOI: 10.1128/Mcb.23.16.5836-5848.2003 |
0.648 |
|
2003 |
Nick McElhinny SA, Ramsden DA. Polymerase mu is a DNA-directed DNA/RNA polymerase. Molecular and Cellular Biology. 23: 2309-15. PMID 12640116 DOI: 10.1128/Mcb.23.7.2309-2315.2003 |
0.83 |
|
2003 |
Havener JM, Nick McElhinny SA, Bassett E, Gauger M, Ramsden DA, Chaney SG. Translesion synthesis past platinum DNA adducts by human DNA polymerase mu. Biochemistry. 42: 1777-88. PMID 12578393 DOI: 10.1021/Bi0270079 |
0.815 |
|
2002 |
Mahajan KN, Nick McElhinny SA, Mitchell BS, Ramsden DA. Association of DNA polymerase mu (pol mu) with Ku and ligase IV: role for pol mu in end-joining double-strand break repair. Molecular and Cellular Biology. 22: 5194-202. PMID 12077346 DOI: 10.1128/Mcb.22.14.5194-5202.2002 |
0.83 |
|
2002 |
Karmakar P, Piotrowski J, Brosh RM, Sommers JA, Miller SP, Cheng WH, Snowden CM, Ramsden DA, Bohr VA. Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation. The Journal of Biological Chemistry. 277: 18291-302. PMID 11889123 DOI: 10.1074/Jbc.M111523200 |
0.611 |
|
2002 |
Perkins EJ, Nair A, Cowley DO, Van Dyke T, Chang Y, Ramsden DA. Sensing of intermediates in V(D)J recombination by ATM. Genes & Development. 16: 159-64. PMID 11799059 DOI: 10.1101/Gad.956902 |
0.659 |
|
2000 |
Nick McElhinny SA, Snowden CM, McCarville J, Ramsden DA. Ku recruits the XRCC4-ligase IV complex to DNA ends. Molecular and Cellular Biology. 20: 2996-3003. PMID 10757784 DOI: 10.1128/Mcb.20.9.2996-3003.2000 |
0.821 |
|
1999 |
Gellert M, Hesse JE, Hiom K, Melek M, Modesti M, Paull TT, Ramsden DA, Van Gent DC. V(D)J recombination: Links to transposition and double-strand break repair Cold Spring Harbor Symposia On Quantitative Biology. 64: 161-167. PMID 11232281 DOI: 10.1101/Sqb.1999.64.161 |
0.39 |
|
1998 |
Ramsden DA, Gellert M. Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks. The Embo Journal. 17: 609-14. PMID 9430651 DOI: 10.1093/Emboj/17.2.609 |
0.578 |
|
1997 |
Ramsden DA, van Gent DC, Gellert M. Specificity in V(D)J recombination: new lessons from biochemistry and genetics. Current Opinion in Immunology. 9: 114-20. PMID 9039786 DOI: 10.1016/S0952-7915(97)80167-7 |
0.408 |
|
1996 |
Ramsden DA, McBlane JF, van Gent DC, Gellert M. Distinct DNA sequence and structure requirements for the two steps of V(D)J recombination signal cleavage. The Embo Journal. 15: 3197-3206. DOI: 10.1002/J.1460-2075.1996.Tb00682.X |
0.404 |
|
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