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Nigel Unwin, Ph.D. - Publications

Affiliations: 
University of Cambridge, Cambridge, England, United Kingdom 
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Unwin N. Protein-Lipid Interplay at the Neuromuscular Junction. Microscopy (Oxford, England). PMID 34226930 DOI: 10.1093/jmicro/dfab023  0.324
2021 Unwin N. Protein-Lipid Interplay at the Neuromuscular Junction. Microscopy (Oxford, England). PMID 34226930 DOI: 10.1093/jmicro/dfab023  0.324
2020 Unwin N. Protein-lipid architecture of a cholinergic postsynaptic membrane. Iucrj. 7: 852-859. PMID 32939277 DOI: 10.1107/S2052252520009446  0.386
2017 Unwin N. Segregation of lipids near acetylcholine-receptor channels imaged by cryo-EM. Iucrj. 4: 393-399. PMID 28875026 DOI: 10.1107/S2052252517005243  0.461
2013 Unwin N. Nicotinic acetylcholine receptor and the structural basis of neuromuscular transmission: insights from Torpedo postsynaptic membranes. Quarterly Reviews of Biophysics. 46: 283-322. PMID 24050525 DOI: 10.1017/S0033583513000061  0.538
2013 Zuber B, Unwin N. Structure and superorganization of acetylcholine receptor-rapsyn complexes. Proceedings of the National Academy of Sciences of the United States of America. 110: 10622-7. PMID 23754381 DOI: 10.1073/Pnas.1301277110  0.385
2012 Unwin N, Fujiyoshi Y. Gating movement of acetylcholine receptor caught by plunge-freezing. Journal of Molecular Biology. 422: 617-34. PMID 22841691 DOI: 10.1016/J.Jmb.2012.07.010  0.62
2011 Fisher LS, Ward A, Milligan RA, Unwin N, Potter CS, Carragher B. A helical processing pipeline for EM structure determination of membrane proteins. Methods (San Diego, Calif.). 55: 350-62. PMID 21964395 DOI: 10.1016/J.Ymeth.2011.09.013  0.612
2008 Fujiyoshi Y, Unwin N. Electron crystallography of proteins in membranes. Current Opinion in Structural Biology. 18: 587-92. PMID 18755273 DOI: 10.1016/J.Sbi.2008.07.005  0.536
2005 Unwin N. Refined structure of the nicotinic acetylcholine receptor at 4A resolution. Journal of Molecular Biology. 346: 967-89. PMID 15701510 DOI: 10.1016/J.Jmb.2004.12.031  0.502
2003 Unwin N. Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy. Febs Letters. 555: 91-5. PMID 14630325 DOI: 10.1016/S0014-5793(03)01084-6  0.538
2003 Miyazawa A, Fujiyoshi Y, Unwin N. Structure and gating mechanism of the acetylcholine receptor pore. Nature. 423: 949-55. PMID 12827192 DOI: 10.1038/Nature01748  0.615
2003 Colquhoun D, Shelley C, Hatton C, Unwin N, Sivilotti L. Nicotinic Acetylcholine Receptors Burger's Medicinal Chemistry and Drug Discovery. 357-405. DOI: 10.1002/0471266949.Bmc030  0.462
2002 Unwin N, Miyazawa A, Li J, Fujiyoshi Y. Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the alpha subunits. Journal of Molecular Biology. 319: 1165-76. PMID 12079355 DOI: 10.1016/S0022-2836(02)00381-9  0.586
2002 Unwin N. Structure of the acetylcholine-gated channel. Novartis Foundation Symposium. 245: 5-15; discussion 15-. PMID 12027014 DOI: 10.1002/0470868759.Ch2  0.473
2000 Unwin N. The Croonian Lecture 2000. Nicotinic acetylcholine receptor and the structural basis of fast synaptic transmission. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 355: 1813-29. PMID 11205343 DOI: 10.1098/Rstb.2000.0737  0.526
2000 Tierney ML, Unwin N. Electron microscopic evidence for the assembly of soluble pentameric extracellular domains of the nicotinic acetylcholine receptor. Journal of Molecular Biology. 303: 185-96. PMID 11023785 DOI: 10.1006/Jmbi.2000.4137  0.449
1999 Miyazawa A, Fujiyoshi Y, Stowell M, Unwin N. Nicotinic acetylcholine receptor at 4.6 A resolution: transverse tunnels in the channel wall. Journal of Molecular Biology. 288: 765-86. PMID 10329178 DOI: 10.1006/Jmbi.1999.2721  0.715
1999 Miyazawa A, Fujiyoshi Y, Stowell M, Unwin N. Nicotinic acetylcholine receptor at 4.6 A resolution Seibutsu Butsuri. 39: S108. DOI: 10.2142/Biophys.39.S108_2  0.68
1998 Stowell MH, Miyazawa A, Unwin N. Macromolecular structure determination by electron microscopy: new advances and recent results. Current Opinion in Structural Biology. 8: 595-600. PMID 9818263 DOI: 10.1016/S0959-440X(98)80150-4  0.66
1998 Unwin N. The nicotinic acetylcholine receptor of the Torpedo electric ray. Journal of Structural Biology. 121: 181-90. PMID 9615437 DOI: 10.1006/Jsbi.1997.3949  0.553
1997 Beroukhim R, Unwin N. Distortion correction of tubular crystals: improvements in the acetylcholine receptor structure. Ultramicroscopy. 70: 57-81. PMID 9440347 DOI: 10.1016/S0304-3991(97)00070-3  0.542
1996 Unwin N. Projection structure of the nicotinic acetylcholine receptor: distinct conformations of the alpha subunits. Journal of Molecular Biology. 257: 586-96. PMID 8648626 DOI: 10.1006/Jmbi.1996.0187  0.435
1995 Unwin N. Acetylcholine receptor channel imaged in the open state. Nature. 373: 37-43. PMID 7800037 DOI: 10.1038/373037A0  0.509
1995 Beroukhim R, Unwin N. Three-dimensional location of the main immunogenic region of the acetylcholine receptor. Neuron. 15: 323-31. PMID 7544140 DOI: 10.1016/0896-6273(95)90037-3  0.543
1994 Li M, Unwin N, Stauffer KA, Jan YN, Jan LY. Images of purified Shaker potassium channels. Current Biology : Cb. 4: 110-5. PMID 7953509 DOI: 10.1016/S0960-9822(94)00026-6  0.35
1993 Unwin N. Nicotinic acetylcholine receptor at 9 A resolution. Journal of Molecular Biology. 229: 1101-24. PMID 8445638 DOI: 10.1006/Jmbi.1993.1107  0.509
1993 Unwin N. Neurotransmitter action: opening of ligand-gated ion channels. Cell. 72: 31-41. PMID 7679054 DOI: 10.1016/S0092-8674(05)80026-1  0.409
1992 Stauffer KA, Unwin N. Structure of gap junction channels. Seminars in Cell Biology. 3: 17-20. PMID 1377970 DOI: 10.1016/S1043-4682(10)80004-2  0.418
1991 Stauffer KA, Kumar NM, Gilula NB, Unwin N. Isolation and purification of gap junction channels. The Journal of Cell Biology. 115: 141-50. PMID 1655801 DOI: 10.1083/Jcb.115.1.141  0.331
1990 Toyoshima C, Unwin N. Three-dimensional structure of the acetylcholine receptor by cryoelectron microscopy and helical image reconstruction. The Journal of Cell Biology. 111: 2623-35. PMID 2277076  0.413
1989 Unwin N. The structure of ion channels in membranes of excitable cells. Neuron. 3: 665-76. PMID 2484344 DOI: 10.1016/0896-6273(89)90235-3  0.386
1988 Unwin N, Toyoshima C, Kubalek E. Arrangement of the acetylcholine receptor subunits in the resting and desensitized states, determined by cryoelectron microscopy of crystallized Torpedo postsynaptic membranes. The Journal of Cell Biology. 107: 1123-38. PMID 3417777  0.412
1988 Toyoshima C, Unwin N. Contrast transfer for frozen-hydrated specimens: determination from pairs of defocused images. Ultramicroscopy. 25: 279-91. PMID 3188279 DOI: 10.1016/0304-3991(88)90003-4  0.305
1988 Toyoshima C, Unwin N. Ion channel of acetylcholine receptor reconstructed from images of postsynaptic membranes. Nature. 336: 247-50. PMID 2461515 DOI: 10.1038/336247A0  0.512
1987 Kubalek E, Ralston S, Lindstrom J, Unwin N. Location of subunits within the acetylcholine receptor by electron image analysis of tubular crystals from Torpedo marmorata. The Journal of Cell Biology. 105: 9-18. PMID 3611197 DOI: 10.1083/Jcb.105.1.9  0.302
1978 Unwin N. Three-dimensional-structure analysis by electron microscopy Biochemical Society Transactions. 6: 38. DOI: 10.1042/Bst0060038  0.323
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