| Year |
Citation |
Score |
| 2024 |
Özel F, Di Criscio M, Lupu DI, Sarkisyan D, Hlady RA, Robertson KD, Bakalkin G, Liu Y, Biernacka JM, Karpyak VM, Ekström TJ, Rüegg J. DNA methylation at DLGAP2 and risk for relapse in alcohol dependence during acamprosate treatment. Drug and Alcohol Dependence. 256: 111116. PMID 38364647 DOI: 10.1016/j.drugalcdep.2024.111116 |
0.32 |
|
| 2022 |
Binder M, Carr RM, Lasho TL, Finke CM, Mangaonkar AA, Pin CL, Berger KR, Mazzone A, Potluri S, Ordog T, Robertson KD, Marks DL, Fernandez-Zapico ME, Gaspar-Maia A, Patnaik MM. Oncogenic gene expression and epigenetic remodeling of cis-regulatory elements in ASXL1-mutant chronic myelomonocytic leukemia. Nature Communications. 13: 1434. PMID 35301312 DOI: 10.1038/s41467-022-29142-6 |
0.378 |
|
| 2021 |
Ho AM, Winham SJ, McCauley BM, Kundakovic M, Robertson KD, Sun Z, Ordog T, Webb LM, Frye MA, Veldic M. Plasma Cell-Free DNA Methylomics of Bipolar Disorder With and Without Rapid Cycling. Frontiers in Neuroscience. 15: 774037. PMID 34916903 DOI: 10.3389/fnins.2021.774037 |
0.357 |
|
| 2021 |
Tiedemann RL, Eden HE, Huang Z, Robertson KD, Rothbart SB. Distinguishing Active Versus Passive DNA Demethylation Using Illumina MethylationEPIC BeadChip Microarrays. Methods in Molecular Biology (Clifton, N.J.). 2272: 97-140. PMID 34009611 DOI: 10.1007/978-1-0716-1294-1_7 |
0.452 |
|
| 2020 |
Brown M, Zhang W, Yan D, Kenath R, Le L, Wang H, Delitto D, Ostrov D, Robertson K, Liu C, Pham K. The role of survivin in the progression of pancreatic ductal adenocarcinoma (PDAC) and a novel survivin-targeted therapeutic for PDAC. Plos One. 15: e0226917. PMID 31929540 DOI: 10.1371/Journal.Pone.0226917 |
0.384 |
|
| 2020 |
Luna A, Wu Q, Hlady R, Sathyanarayan A, Rustgi V, Guarrera J, Robertson K, Liu C. Response to Epigenetic Disruption in Tumor Suppressor of Hepatocellular Carcinoma (HCC) The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.08693 |
0.308 |
|
| 2019 |
Wei T, Nie J, Larson NB, Ye Z, Eckel Passow JE, Robertson KD, Kocher JA, Wang L. CpGtools: A Python Package for DNA Methylation Analysis. Bioinformatics (Oxford, England). PMID 31808791 DOI: 10.1093/Bioinformatics/Btz916 |
0.536 |
|
| 2019 |
Hlady RA, Zhao X, Pan X, Yang JD, Ahmed F, Antwi SO, Giama NH, Patel T, Roberts LR, Liu C, Robertson KD. Genome-wide discovery and validation of diagnostic DNA methylation-based biomarkers for hepatocellular cancer detection in circulating cell free DNA. Theranostics. 9: 7239-7250. PMID 31695765 DOI: 10.7150/Thno.35573 |
0.423 |
|
| 2019 |
Zheng Y, Hlady RA, Joyce BT, Robertson KD, He C, Nannini DR, Kibbe WA, Achenbach CJ, Murphy RL, Roberts LR, Hou L. DNA methylation of individual repetitive elements in hepatitis C virus infection-induced hepatocellular carcinoma. Clinical Epigenetics. 11: 145. PMID 31639042 DOI: 10.1186/S13148-019-0733-Y |
0.366 |
|
| 2019 |
Yang M, Hlady RA, Zhou D, Ho TH, Robertson KD. In silico DNA methylation analysis identifies potential prognostic biomarkers in type 2 papillary renal cell carcinoma. Cancer Medicine. PMID 31361072 DOI: 10.1002/Cam4.2402 |
0.451 |
|
| 2019 |
Ho AM, Winham SJ, Armasu SM, Blacker CJ, Millischer V, Lavebratt C, Overholser JC, Jurjus GJ, Dieter L, Mahajan G, Rajkowska G, Vallender EJ, Stockmeier CA, Robertson KD, Frye MA, et al. Genome-wide DNA methylomic differences between dorsolateral prefrontal and temporal pole cortices of bipolar disorder. Journal of Psychiatric Research. 117: 45-54. PMID 31279243 DOI: 10.1016/J.Jpsychires.2019.05.030 |
0.445 |
|
| 2019 |
Zhong J, Ye Z, Clark CR, Lenz SW, Nguyen JH, Yan H, Robertson KD, Farrugia G, Zhang Z, Ordog T, Lee JH. Enhanced and controlled chromatin extraction from FFPE tissues and the application to ChIP-seq. Bmc Genomics. 20: 249. PMID 30922218 DOI: 10.1186/S12864-019-5639-8 |
0.358 |
|
| 2019 |
Wang L, Marek GW, Hlady RA, Wagner RT, Zhao X, Clark VC, Fan AX, Liu C, Brantly M, Robertson KD. Alpha-1 antitrypsin deficiency liver disease, mutational homogeneity modulated by epigenetic heterogeneity with links to obesity. Hepatology (Baltimore, Md.). PMID 30681738 DOI: 10.1002/Hep.30526 |
0.404 |
|
| 2019 |
Binder M, Gaspar Maia A, Carr RM, Lasho T, Witzig TE, Pin C, Berger K, Alver B, Robertson K, Marks D, Fernandez-Zapico M, Patnaik MM. Distal Enhancer Elements in ASXL1-Mutant Chronic Myelomonocytic Leukemia Blood. 134: 2981-2981. DOI: 10.1182/Blood-2019-124917 |
0.494 |
|
| 2019 |
Carr RM, Lasho T, Marks D, Tolosa E, Almada LL, Alver B, Binder M, Safgren S, Horn I, Berger K, Mangaonkar AA, Antelo GB, Coltro G, Pin C, Witzig TE, ... Robertson K, et al. Clinical Categorization of Chronic Myelomonocytic Leukemia into Proliferative and Dysplastic Subtypes Correlates with Distinct Genomic, Transcriptomic and Epigenomic Signatures Blood. 134: 1710-1710. DOI: 10.1182/Blood-2019-123877 |
0.374 |
|
| 2019 |
Binder M, Gaspar Maia A, Carr RM, Pin C, Berger K, Alver B, Robertson K, Marks D, Fernandez-Zapico M, Patnaik MM. Epigenomic Determinants of Transcriptional Activity in ASXL1-Mutant Chronic Myelomonocytic Leukemia Blood. 134: 2987-2987. DOI: 10.1182/Blood-2019-123191 |
0.527 |
|
| 2019 |
Zhong J, Ye Z, Clark C, Lenz S, Nguyen J, Yan H, Robertson K, Farrugia G, Zhang Z, Ordog T, Lee J. Abstract 5180: Enhanced and controlled chromatin extraction for chromatin-based epigenetic assays in FFPE tissues Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-5180 |
0.385 |
|
| 2018 |
Liu J, Hanavan PD, Kras K, Ruiz YW, Castle EP, Lake DF, Chen X, O'Brien D, Luo H, Robertson KD, Gu H, Ho TH. Loss of SETD2 induces a metabolic switch in renal cell carcinoma cell lines toward enhanced oxidative phosphorylation. Journal of Proteome Research. PMID 30406665 DOI: 10.1021/Acs.Jproteome.8B00628 |
0.304 |
|
| 2018 |
Rosen AD, Robertson KD, Hlady RA, Muench C, Lee J, Philibert R, Horvath S, Kaminsky ZA, Lohoff FW. DNA methylation age is accelerated in alcohol dependence. Translational Psychiatry. 8: 182. PMID 30185790 DOI: 10.1038/S41398-018-0233-4 |
0.395 |
|
| 2018 |
Hlady RA, Sathyanarayan A, Thompson JJ, Zhou D, Wu Q, Pham K, Lee JH, Liu C, Robertson KD. Integrating the Epigenome to Identify Novel Drivers of Hepatocellular Carcinoma. Hepatology (Baltimore, Md.). PMID 30136421 DOI: 10.1002/Hep.30211 |
0.447 |
|
| 2018 |
Thompson JJ, Kaur R, Sosa CP, Lee JH, Kashiwagi K, Zhou D, Robertson KD. ZBTB24 is a transcriptional regulator that coordinates with DNMT3B to control DNA methylation. Nucleic Acids Research. PMID 30085123 DOI: 10.1093/Nar/Gky682 |
0.511 |
|
| 2018 |
Hlady RA, Robertson KD. A three-pronged epigenetic approach to the treatment of hepatocellular carcinoma. Hepatology (Baltimore, Md.). PMID 30070376 DOI: 10.1002/Hep.30133 |
0.307 |
|
| 2018 |
Marks DL, Olson RL, Urrutia R, Billadeau DD, Roy N, Calin GA, Fabbri M, Koutsioumpa M, Iliopoulos D, Ordog T, Huebert R, Sarmento O, Bamidele AO, Faubion W, Lomberk GL, ... ... Robertson K, et al. Epigenetics of gastrointestinal diseases: notes from a workshop. Epigenetics. 1-9. PMID 30056798 DOI: 10.1080/15592294.2018.1464351 |
0.456 |
|
| 2018 |
Ibrahim SH, Robertson KD. Use of the CRISPR/Cas9-Based Epigenetic Gene Activation System in Vivo: a New Potential Therapeutic Modality. Hepatology (Baltimore, Md.). PMID 29489018 DOI: 10.1002/Hep.29860 |
0.344 |
|
| 2018 |
Hlady RA, Robertson KD. Genetic and Epigenetic Heterogeneity in Normal Liver Homeostasis and Its Implications for Liver Disease and Hepatocellular Cancer. Seminars in Liver Disease. 38: 41-50. PMID 29471564 DOI: 10.1055/S-0037-1621712 |
0.333 |
|
| 2018 |
Torres-Gutierrez CJ, Heckman MG, Hlady RA, Ketterling RP, Sproat LZ, Pearce KE, Lesser ER, Diehl NN, Finn LE, Jiang LJ, Robertson KD, Cerhan JR, Foran JM. Association of Clinical Epidemiologic Exposures and Overall Survival with Genome-Wide DNA Methylation Profiles in Acute Myeloid Leukemia: Analysis of the Mayo Clinic AML Epidemiology Cohort Blood. 132: 3987-3987. DOI: 10.1182/Blood-2018-99-119386 |
0.433 |
|
| 2018 |
Mangaonkar AA, Reichard KK, Chiu A, Howard MT, King RL, Carr RM, Alver BM, Robertson KD, Cousin M, Villasboas JC, Fernandez-Zapico ME, Lasho TL, Gangat N, Al-Kali A, Elliott MA, et al. Indoleamine 2,3-Dioxygenase-1 Expressing Dendritic Cell Populations Are Associated with Tumor-Induced Immune Tolerance & Aggressive Disease Biology in Chronic Myelomonocytic Leukemia Blood. 132: 4344-4344. DOI: 10.1182/Blood-2018-99-113881 |
0.302 |
|
| 2018 |
Hlady R, Rustgi VK, Robertson K, Liu C. Su1503 - The Evolution of Dna Methylation Changes in Nonalcoholic Fatty Liver Disease to Cirrhosis and Liver Cancer Gastroenterology. 154: S-1160. DOI: 10.1016/S0016-5085(18)33844-7 |
0.382 |
|
| 2017 |
Zhong J, Ye Z, Lenz SW, Clark CR, Bharucha A, Farrugia G, Robertson KD, Zhang Z, Ordog T, Lee JH. Purification of nanogram-range immunoprecipitated DNA in ChIP-seq application. Bmc Genomics. 18: 985. PMID 29268714 DOI: 10.1186/S12864-017-4371-5 |
0.499 |
|
| 2017 |
Wu Q, Pi L, Le Trinh T, Zuo C, Xia M, Jiao Y, Hou Z, Jo S, Puszyk W, Pham K, Nelson DR, Robertson K, Ostrov D, Rameshwar P, Xia CQ, et al. A Novel Vaccine Targeting Glypican-3 as a Treatment for Hepatocellular Carcinoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28865999 DOI: 10.1016/J.Ymthe.2017.08.005 |
0.304 |
|
| 2017 |
Hlady RA, Zhou D, Puszyk W, Roberts LR, Liu C, Robertson KD. Initiation of aberrant DNA methylation patterns and heterogeneity in precancerous lesions of human hepatocellular cancer. Epigenetics. 0. PMID 28059585 DOI: 10.1080/15592294.2016.1277297 |
0.501 |
|
| 2017 |
Yang J, Hlady R, Mohamed E, Gores G, Roberts L, Robertson K. Novel circulating cell free DNA methylation alterations as a biomarker for the detection of hepatocellular carcinoma Journal of Hepatology. 66: S453. DOI: 10.1016/S0168-8278(17)31285-0 |
0.384 |
|
| 2016 |
Piao Y, Lee SK, Lee EJ, Robertson KD, Shi H, Ryu KH, Choi JH. CAME: Identification of Chromatin Accessibility from Nucleosome Occupancy and Methylome Sequencing. Bioinformatics (Oxford, England). PMID 28035030 DOI: 10.1093/Bioinformatics/Btw785 |
0.497 |
|
| 2016 |
Zhou D, Hlady RA, Schafer MJ, White TA, Liu C, Choi JH, Miller JD, Roberts LR, LeBrasseur NK, Robertson KD. High Fat Diet and Exercise Lead to a Disrupted and Pathogenic DNA Methylome in Mouse Liver. Epigenetics. 0. PMID 27858497 DOI: 10.1080/15592294.2016.1261239 |
0.392 |
|
| 2016 |
Yun S, Vincelette ND, Abraham I, Robertson KD, Fernandez-Zapico ME, Patnaik MM. Targeting epigenetic pathways in acute myeloid leukemia and myelodysplastic syndrome: a systematic review of hypomethylating agents trials. Clinical Epigenetics. 8: 68. PMID 27307795 DOI: 10.1186/S13148-016-0233-2 |
0.412 |
|
| 2016 |
Zhang W, Li Y, Kulik M, Tiedemann RL, Robertson KD, Dalton S, Zhao S. Nucleosome positioning changes during human embryonic stem cell differentiation. Epigenetics. 0. PMID 27088311 DOI: 10.1080/15592294.2016.1176649 |
0.418 |
|
| 2016 |
Shreders A, Heckman M, Zhou D, Yang M, Finn LE, Sproat L, Jiang L, Diehl N, Hlady R, Ketterling RP, Tibes R, Robertson KD, Foran JM. Unique Clinical Epidemiologic Risk Factors Are Associated with Distinct Methylation Subgroups in Newly-Diagnosed Acute Myeloid Leukemia (AML) Blood. 128: 1719-1719. DOI: 10.1182/Blood.V128.22.1719.1719 |
0.393 |
|
| 2015 |
Tiedemann RL, Hlady RA, Hanavan PD, Lake DF, Tibes R, Lee JH, Choi JH, Ho TH, Robertson KD. Dynamic reprogramming of DNA methylation in SETD2-deregulated renal cell carcinoma. Oncotarget. PMID 26646321 DOI: 10.18632/Oncotarget.6481 |
0.537 |
|
| 2015 |
Zhao X, Puszyk WM, Lu Z, Ostrov DA, George TJ, Robertson KD, Liu C. Small molecule inhibitor YM155-mediated activation of death receptor 5 is crucial for chemotherapy-induced apoptosis in pancreatic carcinoma. Molecular Cancer Therapeutics. 14: 80-9. PMID 25344582 DOI: 10.1158/1535-7163.Mct-14-0229 |
0.325 |
|
| 2014 |
Tiedemann RL, Putiri EL, Lee JH, Hlady RA, Kashiwagi K, Ordog T, Zhang Z, Liu C, Choi JH, Robertson KD. Acute depletion redefines the division of labor among DNA methyltransferases in methylating the human genome. Cell Reports. 9: 1554-66. PMID 25453758 DOI: 10.1016/J.Celrep.2014.10.013 |
0.604 |
|
| 2014 |
Hlady RA, Tiedemann RL, Puszyk W, Zendejas I, Roberts LR, Choi JH, Liu C, Robertson KD. Epigenetic signatures of alcohol abuse and hepatitis infection during human hepatocarcinogenesis. Oncotarget. 5: 9425-43. PMID 25294808 DOI: 10.18632/Oncotarget.2444 |
0.438 |
|
| 2014 |
Putiri EL, Tiedemann RL, Liu C, Choi JH, Robertson KD. Impact of human MLL/COMPASS and polycomb complexes on the DNA methylome. Oncotarget. 5: 6338-52. PMID 25071008 DOI: 10.18632/Oncotarget.2215 |
0.603 |
|
| 2014 |
Putiri EL, Tiedemann RL, Thompson JJ, Liu C, Ho T, Choi JH, Robertson KD. Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells. Genome Biology. 15: R81. PMID 24958354 DOI: 10.1186/Gb-2014-15-6-R81 |
0.396 |
|
| 2014 |
Putiri EL, Tiedemann RL, Choi J, Robertson KD. Abstract 2319: Dynamics of TET methylcytosine dioxygenases in 5-methylcytosine and 5-hydroxymethylcytosine patterning in human cancer cells Cancer Research. 74: 2319-2319. DOI: 10.1158/1538-7445.Am2014-2319 |
0.567 |
|
| 2014 |
Hlady RA, Tiedemann R, Puszyk W, Liu C, Choi J, Robertson KD. Abstract 2309: Identification of common and unique epigenetic signatures of chronic hepatitis infection and alcohol abuse in human liver disease Cancer Research. 74: 2309-2309. DOI: 10.1158/1538-7445.Am2014-2309 |
0.468 |
|
| 2014 |
Tiedemann R, Choi J, Robertson K. Abstract 2305: Acute depletion reveals novel co-regulation of DNA methylation at conserved loci by DNMT1 and DNMT3B Cancer Research. 74: 2305-2305. DOI: 10.1158/1538-7445.Am2014-2305 |
0.602 |
|
| 2013 |
Jin B, Robertson KD. DNA methyltransferases, DNA damage repair, and cancer. Advances in Experimental Medicine and Biology. 754: 3-29. PMID 22956494 DOI: 10.1007/978-1-4419-9967-2_1 |
0.551 |
|
| 2013 |
Tiedemann RL, Choi J, Robertson KD. Abstract B34: Acute depletion reveals novel divisions of labor among human DNA methyltransferases in cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-B34 |
0.608 |
|
| 2013 |
Tiedemann RL, Choi J, Robertson KD. Abstract 2970: Acute depletion of DNA methyltransferases reveals unique and overlapping target sites in cancer. Cancer Research. 73: 2970-2970. DOI: 10.1158/1538-7445.Am2013-2970 |
0.588 |
|
| 2012 |
Jin B, Ernst J, Tiedemann RL, Xu H, Sureshchandra S, Kellis M, Dalton S, Liu C, Choi JH, Robertson KD. Linking DNA methyltransferases to epigenetic marks and nucleosome structure genome-wide in human tumor cells. Cell Reports. 2: 1411-24. PMID 23177624 DOI: 10.1016/J.Celrep.2012.10.017 |
0.618 |
|
| 2012 |
Yoo J, Kim JH, Robertson KD, Medina-Franco JL. Molecular modeling of inhibitors of human DNA methyltransferase with a crystal structure: discovery of a novel DNMT1 inhibitor. Advances in Protein Chemistry and Structural Biology. 87: 219-47. PMID 22607757 DOI: 10.1016/B978-0-12-398312-1.00008-1 |
0.375 |
|
| 2012 |
Zimmerman MA, Singh N, Martin PM, Thangaraju M, Ganapathy V, Waller JL, Shi H, Robertson KD, Munn DH, Liu K. Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G1405-15. PMID 22517765 DOI: 10.1152/Ajpgi.00543.2011 |
0.333 |
|
| 2012 |
Putiri EL, Robertson KD. Abstract 996: MBD-capture coupled with next generation sequencing elucidates genome-wide crosstalk between epigenetic marks and its role in cancer Cancer Research. 72: 996-996. DOI: 10.1158/1538-7445.Am2012-996 |
0.61 |
|
| 2012 |
Tiedemann RL, Robertson KD. Abstract 5009: Identification of DNA methyltransferase target sites in cancer cells Cancer Research. 72: 5009-5009. DOI: 10.1158/1538-7445.Am2012-5009 |
0.593 |
|
| 2012 |
Coothan-Kandaswamy V, Elangovan S, Gopal E, Kim JH, Robertson K, Thangaraju M, Ganapathy V, Prasad PD. Abstract 17: Tumor-suppressive function of SLC5A8 in renal cancer cells Cancer Research. 72: 17-17. DOI: 10.1158/1538-7445.Am2012-17 |
0.422 |
|
| 2012 |
Lee GE, Robertson KD. Abstract 1054: The role of DNMT1 in the DNA damage response Cancer Research. 72: 1054-1054. DOI: 10.1158/1538-7445.Am2012-1054 |
0.531 |
|
| 2011 |
Peng L, Yuan Z, Ling H, Fukasawa K, Robertson K, Olashaw N, Koomen J, Chen J, Lane WS, Seto E. SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities. Molecular and Cellular Biology. 31: 4720-34. PMID 21947282 DOI: 10.1128/Mcb.06147-11 |
0.586 |
|
| 2011 |
Jin B, Li Y, Robertson KD. DNA methylation: superior or subordinate in the epigenetic hierarchy? Genes & Cancer. 2: 607-17. PMID 21941617 DOI: 10.1177/1947601910393957 |
0.598 |
|
| 2011 |
Putiri EL, Robertson KD. Epigenetic mechanisms and genome stability. Clinical Epigenetics. 2: 299-314. PMID 21927626 DOI: 10.1007/S13148-010-0017-Z |
0.517 |
|
| 2011 |
Liu F, Liu Q, Yang D, Bollag WB, Robertson K, Wu P, Liu K. Verticillin A overcomes apoptosis resistance in human colon carcinoma through DNA methylation-dependent upregulation of BNIP3. Cancer Research. 71: 6807-16. PMID 21911457 DOI: 10.1158/0008-5472.Can-11-1575 |
0.429 |
|
| 2011 |
Lee EJ, Pei L, Srivastava G, Joshi T, Kushwaha G, Choi JH, Robertson KD, Wang X, Colbourne JK, Zhang L, Schroth GP, Xu D, Zhang K, Shi H. Targeted bisulfite sequencing by solution hybrid selection and massively parallel sequencing. Nucleic Acids Research. 39: e127. PMID 21785137 DOI: 10.1093/Nar/Gkr598 |
0.453 |
|
| 2011 |
Van Emburgh BO, Robertson KD. Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants. Nucleic Acids Research. 39: 4984-5002. PMID 21378119 DOI: 10.1093/Nar/Gkr116 |
0.521 |
|
| 2011 |
Liu H, Dong H, Robertson K, Liu C. DNA methylation suppresses expression of the urea cycle enzyme carbamoyl phosphate synthetase 1 (CPS1) in human hepatocellular carcinoma. American Journal of Pathology. 178: 652-661. PMID 21281797 DOI: 10.1016/J.Ajpath.2010.10.023 |
0.438 |
|
| 2011 |
Ha K, Lee GE, Palii SS, Brown KD, Takeda Y, Liu K, Bhalla KN, Robertson KD. Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery. Human Molecular Genetics. 20: 126-40. PMID 20940144 DOI: 10.1093/Hmg/Ddq451 |
0.529 |
|
| 2011 |
Dyer LM, Schooler KP, Ai L, Klop C, Qiu J, Robertson KD, Brown KD. The transglutaminase 2 gene is aberrantly hypermethylated in glioma. Journal of Neuro-Oncology. 101: 429-40. PMID 20596752 DOI: 10.1007/S11060-010-0277-7 |
0.462 |
|
| 2010 |
Jin B, Robertson KD. Abstract 4874: Epigenetic gene silencing is co-regulated by DNMT3B and polycomb-mediated histone modifications in human cancer Cancer Research. 70: 4874-4874. DOI: 10.1158/1538-7445.Am10-4874 |
0.565 |
|
| 2010 |
Li Y, Emburgh BOV, Jin B, Robertson KD. Abstract 4868: Interaction between DNMT3B and polycomb repression complexes and their role in histone modification Cancer Research. 70: 4868-4868. DOI: 10.1158/1538-7445.Am10-4868 |
0.612 |
|
| 2010 |
Ha K, Robertson KD, Bhalla KN. Abstract 485: Role of DNA methyltransferase I (DNMT1) in the DNA damage response Cancer Research. 70: 485-485. DOI: 10.1158/1538-7445.Am10-485 |
0.509 |
|
| 2010 |
Emburgh BOV, Robertson KD. Abstract 145: Interactions among DNA methyltransferase isoforms and their effects on DNA methylation Cancer Research. 70: 145-145. DOI: 10.1158/1538-7445.Am10-145 |
0.58 |
|
| 2009 |
Gopalakrishnan S, Van Emburgh BO, Shan J, Su Z, Fields CR, Vieweg J, Hamazaki T, Schwartz PH, Terada N, Robertson KD. A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding. Molecular Cancer Research : McR. 7: 1622-34. PMID 19825994 DOI: 10.1158/1541-7786.Mcr-09-0018 |
0.803 |
|
| 2009 |
Jin B, Yao B, Li JL, Fields CR, Delmas AL, Liu C, Robertson KD. DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer. Cancer Research. 69: 7412-21. PMID 19723660 DOI: 10.1158/0008-5472.Can-09-0116 |
0.552 |
|
| 2009 |
Zeng W, de Greef JC, Chen YY, Chien R, Kong X, Gregson HC, Winokur ST, Pyle A, Robertson KD, Schmiesing JA, Kimonis VE, Balog J, Frants RR, Ball AR, Lock LF, et al. Specific loss of histone H3 lysine 9 trimethylation and HP1gamma/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD). Plos Genetics. 5: e1000559. PMID 19593370 DOI: 10.1371/Journal.Pgen.1000559 |
0.416 |
|
| 2009 |
Gopalakrishnan S, Sullivan BA, Trazzi S, Della Valle G, Robertson KD. DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions. Human Molecular Genetics. 18: 3178-93. PMID 19482874 DOI: 10.1093/Hmg/Ddp256 |
0.794 |
|
| 2009 |
Demircan B, Dyer LM, Gerace M, Lobenhofer EK, Robertson KD, Brown KD. Comparative epigenomics of human and mouse mammary tumors. Genes, Chromosomes & Cancer. 48: 83-97. PMID 18836996 DOI: 10.1002/Gcc.20620 |
0.445 |
|
| 2008 |
Gopalakrishnan S, Van Emburgh BO, Robertson KD. DNA methylation in development and human disease. Mutation Research. 647: 30-8. PMID 18778722 DOI: 10.1016/J.Mrfmmm.2008.08.006 |
0.809 |
|
| 2008 |
Qiu J, Ai L, Ramachandran C, Yao B, Gopalakrishnan S, Fields CR, Delmas AL, Dyer LM, Melnick SJ, Yachnis AT, Schwartz PH, Fine HA, Brown KD, Robertson KD. Invasion suppressor cystatin E/M (CST6): high-level cell type-specific expression in normal brain and epigenetic silencing in gliomas. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 910-25. PMID 18607344 DOI: 10.1038/Labinvest.2008.66 |
0.765 |
|
| 2008 |
Jin B, Tao Q, Peng J, Soo HM, Wu W, Ying J, Fields CR, Delmas AL, Liu X, Qiu J, Robertson KD. DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. Human Molecular Genetics. 17: 690-709. PMID 18029387 DOI: 10.1093/Hmg/Ddm341 |
0.571 |
|
| 2008 |
Palii SS, Van Emburgh BO, Sankpal UT, Brown KD, Robertson KD. DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B. Molecular and Cellular Biology. 28: 752-71. PMID 17991895 DOI: 10.1128/Mcb.01799-07 |
0.526 |
|
| 2007 |
Palii SS, Robertson KD. Epigenetic control of tumor suppression. Critical Reviews in Eukaryotic Gene Expression. 17: 295-316. PMID 17725495 DOI: 10.1615/Critreveukargeneexpr.V17.I4.40 |
0.488 |
|
| 2007 |
Jung Y, Park J, Kim TY, Park JH, Jong HS, Im SA, Robertson KD, Bang YJ, Kim TY. Potential advantages of DNA methyltransferase 1 (DNMT1)-targeted inhibition for cancer therapy. Journal of Molecular Medicine (Berlin, Germany). 85: 1137-48. PMID 17571247 DOI: 10.1007/S00109-007-0216-Z |
0.496 |
|
| 2007 |
Chan SL, Cui Y, van Hasselt A, Li H, Srivastava G, Jin H, Ng KM, Wang Y, Lee KY, Tsao GS, Zhong S, Robertson KD, Rha SY, Chan AT, Tao Q. The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas. Laboratory Investigation; a Journal of Technical Methods and Pathology. 87: 644-50. PMID 17384664 DOI: 10.1038/Labinvest.3700547 |
0.51 |
|
| 2007 |
Brown KD, Robertson KD. DNMT1 knockout delivers a strong blow to genome stability and cell viability Nature Genetics. 39: 289-290. PMID 17325677 DOI: 10.1038/Ng0307-289 |
0.446 |
|
| 2007 |
Zhong S, Fields CR, Su N, Pan YX, Robertson KD. Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer. Oncogene. 26: 2621-34. PMID 17043644 DOI: 10.1038/Sj.Onc.1210041 |
0.493 |
|
| 2007 |
Robertson KD, Sankpal U, Brown KD. The DNA methylation inhibitor 5‐aza‐2′‐deoxycytidine (5‐azadC) induces reversible genome‐wide DNA damage that is distinctly influenced by DNA methyltransferases (DNMTs) 1 and 3B The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A660-C |
0.506 |
|
| 2006 |
Kim TY, Bang YJ, Robertson KD. Histone deacetylase inhibitors for cancer therapy. Epigenetics. 1: 14-23. PMID 17998811 DOI: 10.4161/Epi.1.1.2644 |
0.483 |
|
| 2006 |
Zhao LY, Niu Y, Santiago A, Liu J, Albert SH, Robertson KD, Liao D. An EBF3-mediated transcriptional program that induces cell cycle arrest and apoptosis. Cancer Research. 66: 9445-52. PMID 17018599 DOI: 10.1158/0008-5472.Can-06-1713 |
0.411 |
|
| 2006 |
Ai L, Kim WJ, Kim TY, Fields CR, Massoll NA, Robertson KD, Brown KD. Epigenetic silencing of the tumor suppressor cystatin M occurs during breast cancer progression. Cancer Research. 66: 7899-909. PMID 16912163 DOI: 10.1158/0008-5472.Can-06-0576 |
0.395 |
|
| 2006 |
Kim TY, Zhong S, Fields CR, Kim JH, Robertson KD. Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. Cancer Research. 66: 7490-501. PMID 16885346 DOI: 10.1158/0008-5472.Can-05-4552 |
0.574 |
|
| 2006 |
Ai L, Tao Q, Zhong S, Fields CR, Kim WJ, Lee MW, Cui Y, Brown KD, Robertson KD. Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer. Carcinogenesis. 27: 1341-8. PMID 16501252 DOI: 10.1093/Carcin/Bgi379 |
0.426 |
|
| 2005 |
Robertson KD. DNA methylation and human disease. Nature Reviews. Genetics. 6: 597-610. PMID 16136652 DOI: 10.1038/Nrg1655 |
0.581 |
|
| 2004 |
Yokochi T, Robertson KD. Doxorubicin inhibits DNMT1, resulting in conditional apoptosis. Molecular Pharmacology. 66: 1415-20. PMID 15340041 DOI: 10.1124/Mol.104.002634 |
0.481 |
|
| 2004 |
Robertson AK, Geiman TM, Sankpal UT, Hager GL, Robertson KD. Effects of chromatin structure on the enzymatic and DNA binding functions of DNA methyltransferases DNMT1 and Dnmt3a in vitro. Biochemical and Biophysical Research Communications. 322: 110-8. PMID 15313181 DOI: 10.1016/J.Bbrc.2004.07.083 |
0.556 |
|
| 2004 |
Yokochi T, Robertson KD. DMB (DNMT-magnetic beads) assay: measuring DNA methyltransferase activity in vitro. Methods in Molecular Biology (Clifton, N.J.). 287: 285-96. PMID 15273420 DOI: 10.1385/1-59259-828-5:285 |
0.515 |
|
| 2004 |
Espada J, Ballestar E, Fraga MF, Villar-Garea A, Juarranz A, Stockert JC, Robertson KD, Fuks F, Esteller M. Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern. The Journal of Biological Chemistry. 279: 37175-84. PMID 15220328 DOI: 10.1074/Jbc.M404842200 |
0.538 |
|
| 2004 |
Yokochi T, Robertson KD. Dimethyl sulfoxide stimulates the catalytic activity of de novo DNA methyltransferase 3a (Dnmt3a) in vitro. Bioorganic Chemistry. 32: 234-43. PMID 15210338 DOI: 10.1016/J.Bioorg.2004.04.005 |
0.449 |
|
| 2004 |
Geiman TM, Sankpal UT, Robertson AK, Chen Y, Mazumdar M, Heale JT, Schmiesing JA, Kim W, Yokomori K, Zhao Y, Robertson KD. Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery. Nucleic Acids Research. 32: 2716-29. PMID 15148359 DOI: 10.1093/Nar/Gkh589 |
0.558 |
|
| 2004 |
Geiman TM, Sankpal UT, Robertson AK, Zhao Y, Zhao Y, Robertson KD. DNMT3B interacts with hSNF2H chromatin remodeling enzyme, HDACs 1 and 2, and components of the histone methylation system. Biochemical and Biophysical Research Communications. 318: 544-55. PMID 15120635 DOI: 10.1016/J.Bbrc.2004.04.058 |
0.574 |
|
| 2004 |
Chan AT, Tao Q, Robertson KD, Flinn IW, Mann RB, Klencke B, Kwan WH, Leung TW, Johnson PJ, Ambinder RF. Azacitidine induces demethylation of the Epstein-Barr virus genome in tumors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 1373-81. PMID 15007085 DOI: 10.1200/Jco.2004.04.185 |
0.485 |
|
| 2004 |
Ling Y, Sankpal UT, Robertson AK, McNally JG, Karpova T, Robertson KD. Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription. Nucleic Acids Research. 32: 598-610. PMID 14752048 DOI: 10.1093/Nar/Gkh195 |
0.474 |
|
| 2003 |
Tao Q, Robertson KD. Stealth technology: how Epstein-Barr virus utilizes DNA methylation to cloak itself from immune detection. Clinical Immunology (Orlando, Fla.). 109: 53-63. PMID 14585276 DOI: 10.1016/S1521-6616(03)00198-0 |
0.551 |
|
| 2002 |
Geiman TM, Robertson KD. Chromatin remodeling, histone modifications, and DNA methylation-how does it all fit together? Journal of Cellular Biochemistry. 87: 117-25. PMID 12244565 DOI: 10.1002/Jcb.10286 |
0.565 |
|
| 2002 |
Tao Q, Huang H, Geiman TM, Lim CY, Fu L, Qiu GH, Robertson KD. Defective de novo methylation of viral and cellular DNA sequences in ICF syndrome cells. Human Molecular Genetics. 11: 2091-102. PMID 12189161 DOI: 10.1093/Hmg/11.18.2091 |
0.499 |
|
| 2002 |
Robertson KD. DNA methylation and chromatin - unraveling the tangled web. Oncogene. 21: 5361-79. PMID 12154399 DOI: 10.1038/Sj.Onc.1205609 |
0.607 |
|
| 2002 |
Yokochi T, Robertson KD. Preferential methylation of unmethylated DNA by Mammalian de novo DNA methyltransferase Dnmt3a. The Journal of Biological Chemistry. 277: 11735-45. PMID 11821381 DOI: 10.1074/Jbc.M106590200 |
0.543 |
|
| 2001 |
Robertson KD. DNA methylation, methyltransferases, and cancer Oncogene. 20: 3139-3155. PMID 11420731 DOI: 10.1038/Sj.Onc.1204341 |
0.582 |
|
| 2001 |
Robertson KD, Wolffe AP. DNA methylation in health and disease. Nature Reviews. Genetics. 1: 11-9. PMID 11262868 DOI: 10.1038/35049533 |
0.541 |
|
| 2000 |
Robertson KD, Ait-Si-Ali S, Yokochi T, Wade PA, Jones PL, Wolffe AP. DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters. Nature Genetics. 25: 338-42. PMID 10888886 DOI: 10.1038/77124 |
0.6 |
|
| 2000 |
Robertson KD. The role of DNA methylation in modulating Epstein-Barr virus gene expression. Current Topics in Microbiology and Immunology. 249: 21-34. PMID 10802936 DOI: 10.1007/978-3-642-59696-4_2 |
0.497 |
|
| 2000 |
Robertson KD, Keyomarsi K, Gonzales FA, Velicescu M, Jones PA. Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells. Nucleic Acids Research. 28: 2108-13. PMID 10773079 DOI: 10.1093/Nar/28.10.2108 |
0.526 |
|
| 2000 |
Robertson KD, Jones PA. DNA methylation: past, present and future directions. Carcinogenesis. 21: 461-7. PMID 10688866 DOI: 10.1093/Carcin/21.3.461 |
0.613 |
|
| 1999 |
Ambinder RF, Robertson KD, Tao Q. DNA methylation and the Epstein-Barr virus Seminars in Cancer Biology. 9: 369-375. PMID 10547345 DOI: 10.1006/Scbi.1999.0137 |
0.49 |
|
| 1999 |
Bender CM, Gonzalgo ML, Gonzales FA, Nguyen CT, Robertson KD, Jones PA. Roles of cell division and gene transcription in the methylation of CpG islands. Molecular and Cellular Biology. 19: 6690-8. PMID 10490608 DOI: 10.1128/Mcb.19.10.6690 |
0.473 |
|
| 1999 |
Robertson KD, Jones PA. Tissue-specific alternative splicing in the human INK4a/ARF cell cycle regulatory locus. Oncogene. 18: 3810-20. PMID 10445844 DOI: 10.1038/Sj.Onc.1202737 |
0.355 |
|
| 1999 |
Qian T, Swinnen LJ, Yang J, Srivastava G, Robertson KD, Ambinder RF. Methylation status of the Epstein-Barr virus major latent promoter C in latrogenic B cell lymphoproliferative disease: Application of PCR-based analysis American Journal of Pathology. 155: 619-625. PMID 10433954 DOI: 10.1016/S0002-9440(10)65157-7 |
0.523 |
|
| 1999 |
Robertson KD, Uzvolgyi E, Liang G, Talmadge C, Sumegi J, Gonzales FA, Jones PA. The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Research. 27: 2291-8. PMID 10325416 DOI: 10.1093/Nar/27.11.2291 |
0.567 |
|
| 1998 |
Robertson KD, Jones PA. The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53. Molecular and Cellular Biology. 18: 6457-73. PMID 9774662 DOI: 10.1128/Mcb.18.11.6457 |
0.497 |
|
| 1998 |
Tao Q, Robertson KD, Manns A, Hildesheim A, Ambinder RF. The Epstein-Barr virus major latent promoter Qp is constitutively active, hypomethylated, and methylation sensitive Journal of Virology. 72: 7075-7083. PMID 9696800 DOI: 10.1128/Jvi.72.9.7075-7083.1998 |
0.53 |
|
| 1998 |
Tao Q, Robertson KD, Manns A, Hildesheim A, Ambinder RF. Epstein-Barr virus (EBV) in endemic Burkitt's lymphoma: Molecular analysis of primary tumor tissue Blood. 91: 1373-1381. PMID 9454768 DOI: 10.1182/Blood.V91.4.1373 |
0.457 |
|
| 1997 |
Robertson KD, Jones PA. Dynamic interrelationships between DNA replication, methylation, and repair. American Journal of Human Genetics. 61: 1220-4. PMID 9399916 DOI: 10.1086/301658 |
0.439 |
|
| 1997 |
Robertson KD, Ambinder RF. Methylation of the Epstein-Barr virus genome in normal lymphocytes Blood. 90: 4480-4484. PMID 9373258 DOI: 10.1182/Blood.V90.11.4480.4480_4480_4484 |
0.513 |
|
| 1997 |
Robertson KD, Ambinder RF. Mapping promoter regions that are hypersensitive to methylation-mediated inhibition of transcription: Application of the methylation cassette assay to the Epstein-Barr virus major latency promoter Journal of Virology. 71: 6445-6454. PMID 9261362 DOI: 10.1128/Jvi.71.9.6445-6454.1997 |
0.513 |
|
| 1996 |
Ambinder RF, Robertson KD, Moore SM, Yang J. Epstein-Barr virus as a therapeutic target in Hodgkin's disease and nasopharyngeal carcinoma. Seminars in Cancer Biology. 7: 217-26. PMID 8946606 DOI: 10.1006/Scbi.1996.0029 |
0.351 |
|
| 1996 |
Robertson KD, Manns A, Swinnen LJ, Zong JC, Gulley ML, Ambinder RF. CpG methylation of the major Epstein-Barr virus latency promoter in Burkitt's lymphoma and Hodgkin's disease Blood. 88: 3129-3136. PMID 8874213 DOI: 10.1182/Blood.V88.8.3129.Bloodjournal8883129 |
0.455 |
|
| 1995 |
Robertson KD, Hayward SD, Ling PD, Samid D, Ambinder RF. Transcriptional activation of the Epstein-Barr virus latency C promoter after 5-azacytidine treatment: evidence that demethylation at a single CpG site is crucial. Molecular and Cellular Biology. 15: 6150-9. PMID 7565767 DOI: 10.1128/Mcb.15.11.6150 |
0.474 |
|
| 1994 |
Robertson KD, Barletta J, Samid D, Ambinder RF. Pharmacologic activation of expression of immunodominant viral antigens: A new strategy for the treatment of Epstein-Barr-virus-associated malignancies Current Topics in Microbiology and Immunology. 194: 145-154. PMID 7534666 DOI: 10.1007/978-3-642-79275-5_18 |
0.313 |
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