| Year |
Citation |
Score |
| 2024 |
Treisman M, Coe L, Zhao Y, Sasi VM, Gullick J, Hansen MH, Ly A, Leichthammer V, Hess C, Machell DL, Schittenhelm RB, Hooper J, Jackson CJ, Tailhades J, De Voss JJ, ... Cryle MJ, et al. An Engineered Biarylitide Cross-Linking P450 from RiPP Biosynthesis Generates Alternative Cyclic Peptides. Organic Letters. PMID 38417822 DOI: 10.1021/acs.orglett.3c04366 |
0.364 |
|
| 2023 |
Marschall E, Cass RW, Prasad KM, Swarbrick JD, McKay AI, Payne JAE, Cryle MJ, Tailhades J. Synthetic ramoplanin analogues are accessible by effective incorporation of arylglycines in solid-phase peptide synthesis. Chemical Science. 15: 195-203. PMID 38131086 DOI: 10.1039/d3sc01944f |
0.343 |
|
| 2023 |
Zhang S, Zhang L, Greule A, Tailhades J, Marschall E, Prasongpholchai P, Leng DJ, Zhang J, Zhu J, Kaczmarski JA, Schittenhelm RB, Einsle O, Jackson CJ, Alberti F, Bechthold A, ... ... Cryle MJ, et al. P450-mediated dehydrotyrosine formation during WS9326 biosynthesis proceeds dehydrogenation of a specific acylated dipeptide substrate. Acta Pharmaceutica Sinica. B. 13: 3561-3574. PMID 37655329 DOI: 10.1016/j.apsb.2023.03.021 |
0.45 |
|
| 2023 |
Ho YTC, Kaczmarski JA, Tailhades J, Izoré T, Steer DL, Schittenhelm RB, Tosin M, Jackson CJ, Cryle MJ. Not always an innocent bystander: the impact of stabilised phosphopantetheine moieties when studying nonribosomal peptide biosynthesis. Chemical Communications (Cambridge, England). PMID 37310188 DOI: 10.1039/d3cc01578e |
0.39 |
|
| 2023 |
Ho YTC, Zhao Y, Tailhades J, Cryle MJ. A Chemoenzymatic Approach to Investigate Cytochrome P450 Cross-Linking in Glycopeptide Antibiotic Biosynthesis. Methods in Molecular Biology (Clifton, N.J.). 2670: 187-206. PMID 37184705 DOI: 10.1007/978-1-0716-3214-7_9 |
0.43 |
|
| 2022 |
Ho YTC, Schittenhelm RB, Iftime D, Stegmann E, Tailhades J, Cryle MJ. Exploring the Flexibility of the Glycopeptide Antibiotic Crosslinking Cascade for Extended Peptide Backbones. Chembiochem : a European Journal of Chemical Biology. e202200686. PMID 36534957 DOI: 10.1002/cbic.202200686 |
0.445 |
|
| 2022 |
Kittilä T, Schoppet M, Cryle MJ. Corrigendum: Online Pyrophosphate Assay for Analyzing Adenylation Domains of Nonribosomal Peptide Synthetases. Chembiochem : a European Journal of Chemical Biology. e202200381. PMID 35892251 DOI: 10.1002/cbic.202200381 |
0.306 |
|
| 2022 |
Zhao Y, Marschall E, Treisman M, McKay A, Padva L, Crüsemann M, Nelson DR, Steer DL, Schittenhelm RB, Tailhades J, Cryle MJ. Cytochrome P450 Enables Versatile Peptide Cyclisation to Generate Histidine- and Tyrosine-Containing Crosslinked Tripeptide Building Blocks. Angewandte Chemie (International Ed. in English). e202204957. PMID 35851739 DOI: 10.1002/anie.202204957 |
0.46 |
|
| 2022 |
Greule A, Izoré T, Machell D, Hansen MH, Schoppet M, De Voss JJ, Charkoudian LK, Schittenhelm RB, Harmer JR, Cryle MJ. The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Frontiers in Chemistry. 10: 868240. PMID 35464232 DOI: 10.3389/fchem.2022.868240 |
0.664 |
|
| 2021 |
Izoré T, Candace Ho YT, Kaczmarski JA, Gavriilidou A, Chow KH, Steer DL, Goode RJA, Schittenhelm RB, Tailhades J, Tosin M, Challis GL, Krenske EH, Ziemert N, Jackson CJ, Cryle MJ. Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. Nature Communications. 12: 2511. PMID 33947858 DOI: 10.1038/s41467-021-22623-0 |
0.399 |
|
| 2021 |
Leng DJ, Greule A, Cryle MJ, Tosin M. Chemical probes reveal the timing of early chlorination in vancomycin biosynthesis. Chemical Communications (Cambridge, England). PMID 33533358 DOI: 10.1039/d0cc07421g |
0.34 |
|
| 2020 |
Kaniusaite M, Goode RJA, Tailhades J, Schittenhelm RB, Cryle MJ. Exploring modular reengineering strategies to redesign the teicoplanin non-ribosomal peptide synthetase. Chemical Science. 11: 9443-9458. PMID 34094211 DOI: 10.1039/d0sc03483e |
0.349 |
|
| 2020 |
Kaniusaite M, Kittilä T, Goode RJA, Schittenhelm RB, Cryle MJ. Redesign of Substrate Selection in Glycopeptide Antibiotic Biosynthesis Enables Effective Formation of Alternate Peptide Backbones. Acs Chemical Biology. 15: 2444-2455. PMID 32794694 DOI: 10.1021/acschembio.0c00435 |
0.348 |
|
| 2020 |
Zhao Y, Ho YTC, Tailhades J, Cryle MJ. Understanding the glycopeptide antibiotic crosslinking cascade - in vitro approaches revealing the details of a complex biosynthesis pathway. Chembiochem : a European Journal of Chemical Biology. PMID 32696500 DOI: 10.1002/cbic.202000309 |
0.416 |
|
| 2020 |
Kaniusaite M, Tailhades J, Kittilä T, Fage CD, Goode RJA, Schittenhelm RB, Cryle MJ. Understanding the early stages of peptide formation during the biosynthesis of teicoplanin and related glycopeptide antibiotics. The Febs Journal. PMID 32359003 DOI: 10.1111/febs.15350 |
0.382 |
|
| 2020 |
Cryle MJ, Tailhades J, Zhao Y, Ho C, Greule A, Ahmed I, Schoppet M, Kulkarni K, Goode RJA, Schittenhelm RB, De Voss JJ. A chemoenzymatic approach to the synthesis of glycopeptide antibiotic analogues. Angewandte Chemie (International Ed. in English). PMID 32297389 DOI: 10.1002/anie.202003726 |
0.674 |
|
| 2020 |
Zhao Y, Goode RJA, Schittenhelm RB, Tailhades J, Cryle MJ. Exploring the Tetracyclization of Teicoplanin Precursor Peptides through Chemoenzymatic Synthesis. The Journal of Organic Chemistry. 85: 1537-1547. PMID 31774678 DOI: 10.1021/acs.joc.9b02640 |
0.45 |
|
| 2019 |
Kaniusaite M, Tailhades J, Marschall EA, Goode RJA, Schittenhelm RB, Cryle MJ. A proof-reading mechanism for non-proteinogenic amino acid incorporation into glycopeptide antibiotics. Chemical Science. 10: 9466-9482. PMID 32055321 DOI: 10.1039/c9sc03678d |
0.44 |
|
| 2019 |
Kaniusaite M, Goode RJA, Schittenhelm RB, Makris TM, Cryle MJ. The Diiron Monooxygenase CmlA from Chloramphenicol Biosynthesis Allows Reconstitution of β-Hydroxylation during Glycopeptide Antibiotic Biosynthesis. Acs Chemical Biology. PMID 31774267 DOI: 10.1021/Acschembio.9B00862 |
0.427 |
|
| 2019 |
Tailhades J, Zhao Y, Schoppet M, Greule A, Goode RJA, Schittenhelm RB, De Voss JJ, Cryle MJ. Enzymatic Cascade To Evaluate the Tricyclization of Glycopeptide Antibiotic Precursor Peptides as a Prequel to Biosynthetic Redesign. Organic Letters. PMID 31603691 DOI: 10.1021/acs.orglett.9b03245 |
0.664 |
|
| 2019 |
Greule A, Izoré T, Iftime D, Tailhades J, Schoppet M, Zhao Y, Peschke M, Ahmed I, Kulik A, Adamek M, Goode RJA, Schittenhelm RB, Kaczmarski JA, Jackson CJ, Ziemert N, ... ... Cryle MJ, et al. Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibiotics. Nature Communications. 10: 2613. PMID 31197182 DOI: 10.1038/S41467-019-10384-W |
0.68 |
|
| 2019 |
Greule A, Charkoudian LK, Cryle MJ. Studying trans-acting enzymes that target carrier protein-bound amino acids during nonribosomal peptide synthesis. Methods in Enzymology. 617: 113-154. PMID 30784400 DOI: 10.1016/Bs.Mie.2018.12.008 |
0.467 |
|
| 2019 |
Schoppet M, Peschke M, Kirchberg A, Wiebach V, Süssmuth RD, Stegmann E, Cryle MJ. The biosynthetic implications of late-stage condensation domain selectivity during glycopeptide antibiotic biosynthesis. Chemical Science. 10: 118-133. PMID 30713624 DOI: 10.1039/C8Sc03530J |
0.387 |
|
| 2019 |
Izoré T, Tailhades J, Hansen MH, Kaczmarski JA, Jackson CJ, Cryle MJ. nonribosomal peptide synthetase Ebony encodes an atypical condensation domain. Proceedings of the National Academy of Sciences of the United States of America. PMID 30705105 DOI: 10.1073/Pnas.1811194116 |
0.301 |
|
| 2018 |
Izoré T, Cryle MJ. The many faces and important roles of protein-protein interactions during non-ribosomal peptide synthesis. Natural Product Reports. 35: 1120-1139. PMID 30207358 DOI: 10.1039/c8np00038g |
0.366 |
|
| 2018 |
Brieke C, Tarnawski M, Greule A, Cryle MJ. Investigating Cytochrome P450 specificity during glycopeptide antibiotic biosynthesis through a homologue hybridization approach. Journal of Inorganic Biochemistry. 185: 43-51. PMID 29751197 DOI: 10.1016/j.jinorgbio.2018.05.001 |
0.419 |
|
| 2018 |
Schoppet M, Tailhades J, Kulkarni K, Cryle MJ. Precursor Manipulation in Glycopeptide Antibiotic Biosynthesis: Are β-Amino Acids Compatible with the Oxidative Cyclization Cascade? The Journal of Organic Chemistry. 83: 7206-7214. PMID 29708747 DOI: 10.1021/acs.joc.8b00418 |
0.465 |
|
| 2018 |
Greule A, Stok JE, De Voss JJ, Cryle MJ. Unrivalled diversity: the many roles and reactions of bacterial cytochromes P450 in secondary metabolism. Natural Product Reports. PMID 29667657 DOI: 10.1039/c7np00063d |
0.627 |
|
| 2018 |
Tailhades J, Schoppet M, Greule A, Peschke M, Brieke C, Cryle MJ. A route to diastereomerically pure phenylglycine thioester peptides: crucial intermediates for investigating glycopeptide antibiotic biosynthesis. Chemical Communications (Cambridge, England). 54: 2146-2149. PMID 29423498 DOI: 10.1039/c7cc09409d |
0.385 |
|
| 2018 |
Peschke M, Brieke C, Heimes M, Cryle MJ. The Thioesterase Domain in Glycopeptide Antibiotic Biosynthesis Is Selective for Cross-Linked Aglycones. Acs Chemical Biology. 13: 110-120. PMID 29192758 DOI: 10.1021/acschembio.7b00943 |
0.394 |
|
| 2017 |
Kittilä T, Kittel C, Tailhades J, Butz D, Schoppet M, Büttner A, Goode RJA, Schittenhelm RB, van Pee KH, Süssmuth RD, Wohlleben W, Cryle MJ, Stegmann E. Halogenation of glycopeptide antibiotics occurs at the amino acid level during non-ribosomal peptide synthesis. Chemical Science. 8: 5992-6004. PMID 28989629 DOI: 10.1039/C7Sc00460E |
0.468 |
|
| 2017 |
Peschke M, Brieke C, Goode RJ, Schittenhelm RB, Cryle MJ. Chlorinated Glycopeptide Antibiotic Peptide Precursors Improve Cytochrome P450-Catalyzed Cyclization Cascade Efficiency. Biochemistry. 56: 1239-1247. PMID 28218515 DOI: 10.1021/acs.biochem.6b01102 |
0.468 |
|
| 2017 |
Mollo A, von Krusenstiern AN, Bulos JA, Ulrich V, Åkerfeldt KS, Cryle MJ, Charkoudian LK. P450 monooxygenase ComJ catalyses side chain phenolic cross-coupling during complestatin biosynthesis Rsc Adv.. 7: 35376-35384. DOI: 10.1039/C7Ra06518C |
0.415 |
|
| 2016 |
Ulrich V, Brieke C, Cryle MJ. Biochemical and structural characterisation of the second oxidative crosslinking step during the biosynthesis of the glycopeptide antibiotic A47934. Beilstein Journal of Organic Chemistry. 12: 2849-2864. PMID 28144358 DOI: 10.3762/bjoc.12.284 |
0.456 |
|
| 2016 |
Payne JA, Schoppet M, Hansen MH, Cryle MJ. Diversity of nature's assembly lines - recent discoveries in non-ribosomal peptide synthesis. Molecular Biosystems. PMID 27853778 DOI: 10.1039/c6mb00675b |
0.362 |
|
| 2016 |
Peschke M, Brieke C, Cryle MJ. F-O-G Ring Formation in Glycopeptide Antibiotic Biosynthesis is Catalysed by OxyE. Scientific Reports. 6: 35584. PMID 27752135 DOI: 10.1038/srep35584 |
0.42 |
|
| 2016 |
Ulrich V, Peschke M, Brieke C, Cryle MJ. More than just recruitment: the X-domain influences catalysis of the first phenolic coupling reaction in A47934 biosynthesis by Cytochrome P450 StaH. Molecular Biosystems. PMID 27477788 DOI: 10.1039/c6mb00373g |
0.357 |
|
| 2016 |
Kittilä T, Mollo A, Charkoudian LK, Cryle MJ. New Structural Data Reveal the Motion of Carrier Proteins in Nonribosomal Peptide Synthesis. Angewandte Chemie (International Ed. in English). PMID 27435901 DOI: 10.1002/Anie.201602614 |
0.366 |
|
| 2016 |
Peschke M, Gonsior M, Süssmuth RD, Cryle MJ. Understanding the crucial interactions between Cytochrome P450s and non-ribosomal peptide synthetases during glycopeptide antibiotic biosynthesis. Current Opinion in Structural Biology. 41: 46-53. PMID 27289043 DOI: 10.1016/J.Sbi.2016.05.018 |
0.47 |
|
| 2016 |
Peschke M, Haslinger K, Brieke C, Reinstein J, Cryle MJ. Regulation of the P450 Oxygenation Cascade Involved in Glycopeptide Antibiotic Biosynthesis. Journal of the American Chemical Society. 138: 6746-53. PMID 27213615 DOI: 10.1021/jacs.6b00307 |
0.788 |
|
| 2016 |
Brieke C, Kratzig V, Peschke M, Cryle MJ. Facile Synthetic Access to Glycopeptide Antibiotic Precursor Peptides for the Investigation of Cytochrome P450 Action in Glycopeptide Antibiotic Biosynthesis. Methods in Molecular Biology (Clifton, N.J.). 1401: 85-102. PMID 26831703 DOI: 10.1007/978-1-4939-3375-4_6 |
0.428 |
|
| 2016 |
Haslinger K, Cryle MJ. Structure of OxyA tei: completing our picture of the glycopeptide antibiotic producing Cytochrome P450 cascade. Febs Letters. 590: 571-81. PMID 26820384 DOI: 10.1002/1873-3468.12081 |
0.752 |
|
| 2015 |
Kokona B, Winesett ES, Nikolai von Krusenstiern A, Cryle MJ, Fairman R, Charkoudian LK. Probing the selectivity of beta-hydroxylation reactions in non-ribosomal peptide synthesis using analytical ultracentrifugation. Analytical Biochemistry. PMID 26655390 DOI: 10.1016/J.Ab.2015.11.011 |
0.487 |
|
| 2015 |
Brieke C, Peschke M, Haslinger K, Cryle MJ. Sequential In Vitro Cyclization by Cytochrome P450 Enzymes of Glycopeptide Antibiotic Precursors Bearing the X-Domain from Nonribosomal Peptide Biosynthesis. Angewandte Chemie (International Ed. in English). 54: 15715-9. PMID 26549530 DOI: 10.1002/anie.201507533 |
0.776 |
|
| 2015 |
Al Toma RS, Brieke C, Cryle MJ, Süssmuth RD. Structural aspects of phenylglycines, their biosynthesis and occurrence in peptide natural products. Natural Product Reports. PMID 25940955 DOI: 10.1039/C5Np00025D |
0.352 |
|
| 2015 |
Haslinger K, Peschke M, Brieke C, Maximowitsch E, Cryle MJ. X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis. Nature. 521: 105-9. PMID 25686610 DOI: 10.1038/nature14141 |
0.772 |
|
| 2015 |
Zhang A, Zhang T, Hall EA, Hutchinson S, Cryle MJ, Wong LL, Zhou W, Bell SG. The crystal structure of the versatile cytochrome P450 enzyme CYP109B1 from Bacillus subtilis. Molecular Biosystems. 11: 869-81. PMID 25587700 DOI: 10.1039/C4Mb00665H |
0.317 |
|
| 2015 |
Haslinger K, Redfield C, Cryle MJ. Structure of the terminal PCP domain of the non-ribosomal peptide synthetase in teicoplanin biosynthesis. Proteins. 83: 711-21. PMID 25586301 DOI: 10.1002/prot.24758 |
0.762 |
|
| 2015 |
Brieke C, Kratzig V, Haslinger K, Winkler A, Cryle MJ. Rapid access to glycopeptide antibiotic precursor peptides coupled with cytochrome P450-mediated catalysis: towards a biomimetic synthesis of glycopeptide antibiotics. Organic & Biomolecular Chemistry. 13: 2012-21. PMID 25501135 DOI: 10.1039/c4ob02452d |
0.764 |
|
| 2014 |
Haslinger K, Maximowitsch E, Brieke C, Koch A, Cryle MJ. Cytochrome P450 OxyBtei catalyzes the first phenolic coupling step in teicoplanin biosynthesis. Chembiochem : a European Journal of Chemical Biology. 15: 2719-28. PMID 25358800 DOI: 10.1002/cbic.201402441 |
0.794 |
|
| 2014 |
Haslinger K, Brieke C, Uhlmann S, Sieverling L, Süssmuth RD, Cryle MJ. The structure of a transient complex of a nonribosomal peptide synthetase and a cytochrome P450 monooxygenase. Angewandte Chemie (International Ed. in English). 53: 8518-22. PMID 25044735 DOI: 10.1002/Anie.201404977 |
0.774 |
|
| 2014 |
Brieke C, Cryle MJ. A facile Fmoc solid phase synthesis strategy to access epimerization-prone biosynthetic intermediates of glycopeptide antibiotics. Organic Letters. 16: 2454-7. PMID 24730694 DOI: 10.1021/ol500840f |
0.308 |
|
| 2013 |
Uhlmann S, Süssmuth RD, Cryle MJ. Cytochrome p450sky interacts directly with the nonribosomal peptide synthetase to generate three amino acid precursors in skyllamycin biosynthesis. Acs Chemical Biology. 8: 2586-96. PMID 24079328 DOI: 10.1021/Cb400555E |
0.377 |
|
| 2013 |
Erk B, Rolles D, Foucar L, Rudek B, Epp SW, Cryle M, Bostedt C, Schorb S, Bozek J, Rouzee A, Hundertmark A, Marchenko T, Simon M, Filsinger F, Christensen L, et al. Ultrafast Charge Rearrangement and Nuclear Dynamics upon Inner-Shell Multiple Ionization of Small Polyatomic Molecules Physical Review Letters. 110. DOI: 10.1103/PhysRevLett.110.053003 |
0.396 |
|
| 2013 |
Erk B, Rolles D, Foucar L, Rudek B, Epp SW, Cryle M, Bostedt C, Schorb S, Bozek J, Rouzee A, Hundertmark A, Marchenko T, Simon M, Filsinger F, Christensen L, et al. Inner-shell multiple ionization of polyatomic molecules with an intense x-ray free-electron laser studied by coincident ion momentum imaging Journal of Physics B: Atomic, Molecular and Optical Physics. 46. DOI: 10.1088/0953-4075/46/16/164031 |
0.419 |
|
| 2012 |
Cryle MJ, Hayes PY, De Voss JJ. Enzyme-substrate complementarity governs access to a cationic reaction manifold in the P450(BM3)-catalysed oxidation of cyclopropyl fatty acids. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 15994-9. PMID 23109039 DOI: 10.1002/chem.201203035 |
0.666 |
|
| 2012 |
Kassemeyer S, Steinbrener J, Lomb L, Hartmann E, Aquila A, Barty A, Martin AV, Hampton CY, Bajt S, Barthelmess M, Barends TR, Bostedt C, Bott M, Bozek JD, Coppola N, ... Cryle M, et al. Femtosecond free-electron laser x-ray diffraction data sets for algorithm development. Optics Express. 20: 4149-58. PMID 22418172 DOI: 10.1364/Oe.20.004149 |
0.408 |
|
| 2012 |
Erk B, Rudenko A, Rolles D, Rudek B, Foucar L, Epp S, Cryle M, Schlichting I, Bostedt C, Schorb S, Bozek J, Rouzee A, Hundertmark A, Marchenko T, Simon M, et al. Coulomb explosion imaging of small organic molecules at LCLS Journal of Physics: Conference Series. 388. DOI: 10.1088/1742-6596/388/2/022108 |
0.393 |
|
| 2011 |
Cryle MJ. Carrier protein substrates in cytochrome P450-catalysed oxidation. Metallomics : Integrated Biometal Science. 3: 323-6. PMID 21243168 DOI: 10.1039/c0mt00081g |
0.329 |
|
| 2011 |
Cryle MJ, Staaden J, Schlichting I. Structural characterization of CYP165D3, a cytochrome P450 involved in phenolic coupling in teicoplanin biosynthesis. Archives of Biochemistry and Biophysics. 507: 163-73. PMID 20974107 DOI: 10.1016/j.abb.2010.10.017 |
0.606 |
|
| 2010 |
Cryle MJ, Bell SG, Schlichting I. Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase. Biochemistry. 49: 7282-96. PMID 20690619 DOI: 10.1021/Bi100910Y |
0.55 |
|
| 2010 |
Cryle MJ. Selectivity in a barren landscape: the P450(BioI)-ACP complex. Biochemical Society Transactions. 38: 934-9. PMID 20658980 DOI: 10.1042/BST0380934 |
0.35 |
|
| 2010 |
Cryle MJ, Meinhart A, Schlichting I. Structural characterization of OxyD, a cytochrome P450 involved in beta-hydroxytyrosine formation in vancomycin biosynthesis. The Journal of Biological Chemistry. 285: 24562-74. PMID 20519494 DOI: 10.1074/jbc.M110.131904 |
0.606 |
|
| 2009 |
Glas AF, Maul MJ, Cryle M, Barends TRM, Schneider S, Kaya E, Schlichting I, Carell T. The archaeal cofactor F0 is a light-harvesting antenna chromophore in eukaryotes Proceedings of the National Academy of Sciences of the United States of America. 106: 11540-11545. PMID 19570997 DOI: 10.1073/Pnas.0812665106 |
0.436 |
|
| 2009 |
Barends T, Domratcheva T, Maul M, Cryle M, Glas A, Schneider S, Carell T, Schlichting I. Light-driven repair of DNA damage by Drosophila (6-4)-photolyase Acta Crystallographica Section A. 65: 17-17. DOI: 10.1107/S0108767309099711 |
0.397 |
|
| 2008 |
Maul MJ, Barends TRM, Glas AF, Cryle MJ, Domratcheva T, Schneider S, Schlichting I, Carell T. Crystal structure and mechanism of a DNA (6-4) photolyase Angewandte Chemie - International Edition. 47: 10076-10080. PMID 18956392 DOI: 10.1002/Anie.200804268 |
0.414 |
|
| 2008 |
Cryle MJ, Schlichting I. Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex. Proceedings of the National Academy of Sciences of the United States of America. 105: 15696-701. PMID 18838690 DOI: 10.1073/pnas.0805983105 |
0.586 |
|
| 2008 |
Kühnel K, Ke N, Cryle MJ, Sligar SG, Schuler MA, Schlichting I. Crystal structures of substrate-free and retinoic acid-bound cyanobacterial cytochrome P450 CYP120A1. Biochemistry. 47: 6552-9. PMID 18512957 DOI: 10.1021/Bi800328S |
0.561 |
|
| 2008 |
Cryle MJ, De Voss JJ. The role of the conserved threonine in P450 BM3 oxygen activation: substrate-determined hydroxylation activity of the Thr268Ala mutant. Chembiochem : a European Journal of Chemical Biology. 9: 261-6. PMID 18161730 DOI: 10.1002/cbic.200700537 |
0.631 |
|
| 2007 |
Kim D, Cryle MJ, De Voss JJ, Ortiz de Montellano PR. Functional expression and characterization of cytochrome P450 52A21 from Candida albicans. Archives of Biochemistry and Biophysics. 464: 213-20. PMID 17400174 DOI: 10.1016/j.abb.2007.02.032 |
0.63 |
|
| 2006 |
Cryle MJ, De Voss JJ. Is the ferric hydroperoxy species responsible for sulfur oxidation in cytochrome p450s? Angewandte Chemie (International Ed. in English). 45: 8221-3. PMID 17111450 DOI: 10.1002/anie.200603411 |
0.562 |
|
| 2006 |
Cryle MJ, Espinoza RD, Smith SJ, Matovic NJ, De Voss JJ. Are branched chain fatty acids the natural substrates for P450(BM3)? Chemical Communications (Cambridge, England). 2353-5. PMID 16733577 DOI: 10.1039/b601202g |
0.622 |
|
| 2005 |
He X, Cryle MJ, De Voss JJ, Ortiz De Montellano PR. Calibration of the channel that determines the ω-hydroxylation regiospecificity of cytochrome P4504A1: Catalytic oxidation of 12-halododecanoic acids Journal of Biological Chemistry. 280: 22697-22705. PMID 15849199 DOI: 10.1074/jbc.M502632200 |
0.584 |
|
| 2005 |
Cryle MJ, Ortiz de Montellano PR, De Voss JJ. Cyclopropyl containing fatty acids as mechanistic probes for cytochromes P450. The Journal of Organic Chemistry. 70: 2455-69. PMID 15787531 DOI: 10.1021/jo047985d |
0.613 |
|
| 2004 |
Cryle MJ, Stuthe JM, Ortiz de Montellano PR, De Voss JJ. Cyclopropyl fatty acids implicate a radical but not a cation as an intermediate in P450BM3-catalysed hydroxylations. Chemical Communications (Cambridge, England). 512-3. PMID 14973583 DOI: 10.1039/b315911f |
0.61 |
|
| 2004 |
Cryle MJ, De Voss JJ. Carbon-carbon bond cleavage by cytochrome p450(BioI)(CYP107H1). Chemical Communications (Cambridge, England). 86-7. PMID 14737344 DOI: 10.1039/b311652b |
0.609 |
|
| 2003 |
Cryle MJ, Matovic NJ, De Voss JJ. Products of cytochrome P450(BioI) (CYP107H1)-catalyzed oxidation of fatty acids. Organic Letters. 5: 3341-4. PMID 12943422 DOI: 10.1021/ol035254e |
0.619 |
|
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