Year |
Citation |
Score |
2019 |
Sernee MF, Ralton JE, Nero TL, Sobala LF, Kloehn J, Vieira-Lara MA, Cobbold SA, Stanton L, Pires DEV, Hanssen E, Males A, Ward T, Bastidas LM, van der Peet PL, Parker MW, et al. A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites. Cell Host & Microbe. 26: 385-399.e9. PMID 31513773 DOI: 10.1016/J.Chom.2019.08.009 |
0.465 |
|
2016 |
Parker LJ, Bocedi A, Ascher DB, Aitken JB, Harris HH, Lo Bello M, Ricci G, Morton CJ, Parker MW. Glutathione transferase P1-1 as an arsenic drug-sequestering enzyme. Protein Science : a Publication of the Protein Society. PMID 27863446 DOI: 10.1002/pro.3084 |
0.499 |
|
2015 |
Hermans SJ, Ascher DB, Hancock NC, Holien JK, Michell BJ, Chai SY, Morton CJ, Parker MW. Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides. Protein Science : a Publication of the Protein Society. 24: 190-9. PMID 25408552 DOI: 10.1002/pro.2604 |
0.564 |
|
2015 |
Hermans SJ, Ascher DB, Hancock NC, Holien JK, Michell BJ, Chai SY, Morton CJ, Parker MW. Crystal structure of human insulin-regulated aminopeptidase with specificity for cyclic peptides Protein Science. 24: 190-199. DOI: 10.1002/pro.2604 |
0.514 |
|
2014 |
Watt AD, Crespi GA, Down RA, Ascher DB, Gunn A, Perez KA, McLean CA, Villemagne VL, Parker MW, Barnham KJ, Miles LA. Anti-Aβ antibody target engagement: a response to Siemers et al. Acta Neuropathologica. 128: 611-4. PMID 25120193 DOI: 10.1007/S00401-014-1333-8 |
0.444 |
|
2014 |
Watt AD, Crespi GA, Down RA, Ascher DB, Gunn A, Perez KA, McLean CA, Villemagne VL, Parker MW, Barnham KJ, Miles LA. Do current therapeutic anti-Aβ antibodies for Alzheimer's disease engage the target? Acta Neuropathologica. 127: 803-10. PMID 24803227 DOI: 10.1007/S00401-014-1290-2 |
0.492 |
|
2014 |
Ascher DB, Wielens J, Nero TL, Doughty L, Morton CJ, Parker MW. Potent hepatitis C inhibitors bind directly to NS5A and reduce its affinity for RNA Scientific Reports. 4. PMID 24755925 DOI: 10.1038/srep04765 |
0.483 |
|
2014 |
Crespi GA, Ascher DB, Parker MW, Miles LA. Crystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer's disease immunotherapy candidate bapineuzumab complexed with amyloid-β. Acta Crystallographica. Section F, Structural Biology Communications. 70: 374-7. PMID 24598931 DOI: 10.1107/S2053230X14001642 |
0.517 |
|
2014 |
Feil SC, Ascher DB, Kuiper MJ, Tweten RK, Parker MW. Structural studies of Streptococcus pyogenes streptolysin O provide insights into the early steps of membrane penetration. Journal of Molecular Biology. 426: 785-92. PMID 24316049 DOI: 10.1016/J.Jmb.2013.11.020 |
0.493 |
|
2012 |
Ascher DB, Polekhina G, Parker MW. Crystallization and preliminary X-ray diffraction analysis of human endoplasmic reticulum aminopeptidase 2. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 68: 468-71. PMID 22505422 DOI: 10.1107/S1744309112006963 |
0.539 |
|
2012 |
Parker LJ, Ascher DB, Gao C, Miles LA, Harris HH, Parker MW. Structural approaches to probing metal interaction with proteins. Journal of Inorganic Biochemistry. 115: 138-47. PMID 22437159 DOI: 10.1016/j.jinorgbio.2012.02.015 |
0.505 |
|
2011 |
Parker LJ, Italiano LC, Morton CJ, Hancock NC, Ascher DB, Aitken JB, Harris HH, Campomanes P, Rothlisberger U, De Luca A, Lo Bello M, Ang WH, Dyson PJ, Parker MW. Studies of glutathione transferase P1-1 bound to a platinum(IV)-based anticancer compound reveal the molecular basis of its activation Chemistry - a European Journal. 17: 7806-7816. PMID 21681839 DOI: 10.1002/chem.201100586 |
0.52 |
|
2011 |
Ascher DB, Cromer BA, Morton CJ, Volitakis I, Cherny RA, Albiston AL, Chai SY, Parker MW. Regulation of insulin-regulated membrane aminopeptidase activity by its C-terminal domain Biochemistry. 50: 2611-2622. PMID 21348480 DOI: 10.1021/bi101893w |
0.539 |
|
2011 |
Parker LJ, Italiano LC, Morton CJ, Hancock NC, Ascher DB, Aitken JB, Harris HH, Campomanes P, Rothlisberger U, De Luca A, Lo Bello M, Ang WH, Dyson PJ, Parker MW. Cover Picture: Studies of Glutathione Transferase P1‐1 Bound to a Platinum(IV)‐Based Anticancer Compound Reveal the Molecular Basis of Its Activation (Chem. Eur. J. 28/2011) Chemistry – a European Journal. 17: 7705-7705. DOI: 10.1002/CHEM.201190140 |
0.472 |
|
2008 |
Chai SY, Yeatman HR, Parker MW, Ascher DB, Thompson PE, Mulvey HT, Albiston AL. Development of cognitive enhancers based on inhibition of insulin-regulated aminopeptidase. Bmc Neuroscience. 9: S14. PMID 19090987 DOI: 10.1186/1471-2202-9-S2-S14 |
0.519 |
|
2008 |
Albiston AL, Morton CJ, Ng HL, Pham V, Yeatman HR, Ye S, Fernando RN, De Bundel D, Ascher DB, Mendelsohn FA, Parker MW, Chai SY. Identification and characterization of a new cognitive enhancer based on inhibition of insulin-regulated aminopeptidase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 4209-17. PMID 18716029 DOI: 10.1096/fj.08-112227 |
0.515 |
|
2008 |
Ye S, Chai SY, Lew RA, Ascher DB, Morton CJ, Parker MW, Albiston AL. Identification of modulating residues defining the catalytic cleft of insulin-regulated aminopeptidase Biochemistry and Cell Biology. 86: 251-261. PMID 18523486 DOI: 10.1139/O08-037 |
0.541 |
|
2008 |
Wun KS, Miles LA, Crespi GA, Wycherley K, Ascher DB, Barnham KJ, Cappai R, Beyreuther K, Masters CL, Parker MW, McKinstry WJ. Crystallization and preliminary X-ray diffraction analysis of the Fab fragment of WO2, an antibody specific for the Abeta peptides associated with Alzheimer's disease. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 64: 438-41. PMID 18453721 DOI: 10.1107/S1744309108011718 |
0.516 |
|
2008 |
Ascher DB, Crespi GAN, Ng HL, Morton CJ, Parker MW, Miles LA. Novel Therapeutic Approaches to Treat Alzheimer’s Disease and Memory Disorders Journal of Proteomics & Bioinformatics. 1: 464-476. DOI: 10.4172/JPB.1000054 |
0.454 |
|
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