Jonathan Alexander Winkler
Affiliations: | 2012 | Boston University, Boston, MA, United States |
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"Jonathan Winkler"Parents
Sign in to add mentor| James J. Collins | grad student | 2012 | Boston University | |
| (Improving antibiotic activity by manipulating bacterial reactive oxygen species metabolism.) | ||||
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Publications
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| Feuerstadt P, Louie TJ, Lashner B, et al. (2022) SER-109, an Oral Microbiome Therapy for Recurrent Infection. The New England Journal of Medicine. 386: 220-229 |
| McGovern BH, Ford CB, Henn MR, et al. (2020) SER-109, an Investigational Microbiome Drug to Reduce Recurrence after Clostridioides difficile infection: Lessons Learned from a Phase 2 Trial. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America |
| Khanna S, Pardi DS, Kelly CR, et al. (2016) A Novel Microbiome Therapeutic Increases Gut Microbial Diversity and Prevents Recurrent Clostridium difficile Infection. The Journal of Infectious Diseases |
| Pandey SP, Winkler JA, Li H, et al. (2014) Central role for RNase YbeY in Hfq-dependent and Hfq-independent small-RNA regulation in bacteria. Bmc Genomics. 15: 121 |
| Morones-Ramirez JR, Winkler JA, Spina CS, et al. (2013) Silver enhances antibiotic activity against gram-negative bacteria. Science Translational Medicine. 5: 190ra81 |
| Dwyer DJ, Winkler JA. (2013) Identification and characterization of programmed cell death markers in bacterial models. Methods in Molecular Biology (Clifton, N.J.). 1004: 145-59 |
| Brynildsen MP, Winkler JA, Spina CS, et al. (2013) Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production. Nature Biotechnology. 31: 160-5 |
| Foti JJ, Devadoss B, Winkler JA, et al. (2012) Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics. Science (New York, N.Y.). 336: 315-9 |
| Davies BW, Kohanski MA, Simmons LA, et al. (2009) Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli. Molecular Cell. 36: 845-60 |