Channing J. Der
Affiliations: | Genetics & Molecular Biology | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
Molecular Biology, Cell BiologyWebsite:
https://unclineberger.org/people/profiles/channing-j.-derGoogle:
"Channing J. Der"Bio:
https://www.ous-research.no/home/institute/news/16792
https://books.google.com/books?id=R7IvAQAAIAAJ
Parents
Sign in to add mentor| Eric J. Stanbridge | grad student | 1981 | UC Irvine (Chemistry Tree) | |
| (Cell surface alterations associated with transformation and tumorgenicity in human cells.) | ||||
| Geoffrey M. Cooper | post-doc | 1982 | Harvard Medical School (Chemistry Tree) | |
Children
Sign in to add trainee| Irem Ozkan-Dagliyan | grad student | University of North Carolina at Chapel Hill School of Medicine (Chemistry Tree) | |
| Kevin Pruitt | grad student | 2001 | UNC Chapel Hill |
| John M. Lambert | grad student | 2002 | UNC Chapel Hill |
| Patricia A. Solski | grad student | 2003 | UNC Chapel Hill |
| Aylin S. Ulku | grad student | 2003 | UNC Chapel Hill |
| Emily J. Chenette | grad student | 2004 | UNC Chapel Hill |
| Todd Palmby | grad student | 2004 | UNC Chapel Hill |
| Jiyoung Cha | grad student | 2007 | UNC Chapel Hill |
| Patrick J. Roberts | grad student | 2007 | UNC Chapel Hill |
| Ariella B. Hanker | grad student | 2009 | UNC Chapel Hill |
| Tanya P. Zand | grad student | 2010 | UNC Chapel Hill |
| Danielle R. Cook | grad student | 2013 | UNC Chapel Hill |
| Gary W. Reuther | post-doc | UNC Chapel Hill |
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Publications
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| DeLiberty JM, Roach MK, Stalnecker CA, et al. (2025) Concurrent Inhibition of the RAS-MAPK Pathway and PIKfyve is a Therapeutic Strategy for Pancreatic Cancer. Cancer Research |
| Isermann T, Sers C, Der CJ, et al. (2024) KRAS inhibitors: resistance drivers and combinatorial strategies. Trends in Cancer |
| Wasko UN, Jiang J, Dalton TC, et al. (2024) Author Correction: Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature |
| Klomp JA, Klomp JE, Stalnecker CA, et al. (2024) Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers. Science (New York, N.Y.). 384: eadk0775 |
| Klomp JE, Diehl JN, Klomp JA, et al. (2024) Determining the ERK-regulated phosphoproteome driving KRAS-mutant cancer. Science (New York, N.Y.). 384: eadk0850 |
| Holderfield M, Lee BJ, Jiang J, et al. (2024) Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Nature |
| Wasko UN, Jiang J, Dalton TC, et al. (2024) Tumor-selective activity of RAS-GTP inhibition in pancreatic cancer. Nature |
| Schaefer A, Hodge RG, Zhang H, et al. (2023) RHOA drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling. Science Signaling. 16: eadg5289 |
| Wasko UN, Jiang J, Curiel-Garcia A, et al. (2023) Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma. Biorxiv : the Preprint Server For Biology |
| Goodwin CM, Waters AM, Klomp JE, et al. (2022) Combination Therapies with CDK4/6 Inhibitors to Treat KRAS-mutant Pancreatic Cancer. Cancer Research |