Aylin S. Ulku, Ph.D.

Affiliations: 
2003 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Molecular Biology, Pharmacology, Cell Biology, Oncology
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"Aylin Ulku"

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Channing J. Der grad student 2003 UNC Chapel Hill
 (*Ras regulation of gene expression in ovarian carcinogenesis.)
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Publications

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Campbell PM, Singh A, Williams FJ, et al. (2006) Genetic and pharmacologic dissection of Ras effector utilization in oncogenesis. Methods in Enzymology. 407: 195-217
Booden MA, Ulku AS, Der CJ. (2006) Cellular assays of oncogene transformation Cell Biology, Four-Volume Set. 1: 345-352
Pruitt K, Ulkü AS, Frantz K, et al. (2005) Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells. The Journal of Biological Chemistry. 280: 23363-70
Collette J, Ulku AS, Der CJ, et al. (2004) Enhanced cathepsin L expression is mediated by different Ras effector pathways in fibroblasts and epithelial cells. International Journal of Cancer. Journal International Du Cancer. 112: 190-9
Eckert LB, Repasky GA, Ulkü AS, et al. (2004) Involvement of Ras activation in human breast cancer cell signaling, invasion, and anoikis. Cancer Research. 64: 4585-92
Ulkü AS, Schäfer R, Der CJ. (2003) Essential role of Raf in Ras transformation and deregulation of matrix metalloproteinase expression in ovarian epithelial cells. Molecular Cancer Research : McR. 1: 1077-88
Vos MD, Ellis CA, Elam C, et al. (2003) RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor. The Journal of Biological Chemistry. 278: 28045-51
Ulkü AS, Der CJ. (2003) Ras signaling, deregulation of gene expression and oncogenesis. Cancer Treatment and Research. 115: 189-208
McFall A, Ulkü A, Lambert QT, et al. (2001) Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase. Molecular and Cellular Biology. 21: 5488-99
Fiordalisi JJ, Johnson RL, Ulkü AS, et al. (2001) Mammalian expression vectors for Ras family proteins: generation and use of expression constructs to analyze Ras family function. Methods in Enzymology. 332: 3-36
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