Jason W. Locasale
Affiliations: | Pharmacology and Cancer Biology | Duke University, Durham, NC |
Area:
nutrition, chemistry, quantitative biology, metabolomics, epigenetics, cancerWebsite:
http://jlocasale.duke.eduGoogle:
"Jason Locasale"Parents
Sign in to add mentor| Arup K. Chakraborty | grad student | 2005-2009 | MIT (Chemistry Tree) |
| Lewis C. Cantley | post-doc | 2008-2012 | Harvard Medical School, Boston, USA |
Children
Sign in to add trainee| Ahmad A. Cluntun | grad student | 2012-2015 | Duke |
| Ziwei Dai | post-doc | 2016- | Duke |
BETA: Related publications
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Publications
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| Eduardo MB, Cottone G, McCloskey CW, et al. (2025) A metabolic shift to the serine pathway induced by lipids fosters epigenetic reprogramming in nontransformed breast cells. Science Advances. 11: eads9182 |
| Liu S, Liu X, Locasale JW. (2024) Quantitation of metabolic activity from isotope tracing data using automated methodology. Nature Metabolism |
| Lv D, Dixit D, Cruz AF, et al. (2024) Metabolic regulation of the glioblastoma stem cell epitranscriptome by malate dehydrogenase 2. Cell Metabolism |
| Patel R, Cooper DE, Kadakia KT, et al. (2024) Targeting glutamine metabolism improves sarcoma response to radiation therapy in vivo. Communications Biology. 7: 608 |
| Kundu A, Brinkley GJ, Nam H, et al. (2024) L-2-hydroxyglutarate remodeling of the epigenome and epitranscriptome creates a metabolic vulnerability in kidney cancer models. The Journal of Clinical Investigation |
| Locasale JW, Goncalves MD, Di Tano M, et al. (2024) Diet and Cancer Metabolism. Cold Spring Harbor Perspectives in Medicine |
| Swanton C, Bernard E, Abbosh C, et al. (2024) Embracing cancer complexity: Hallmarks of systemic disease. Cell. 187: 1589-1616 |
| Liu S, Liu X, Locasale JW. (2024) Quantification of metabolic activity from isotope tracing data using automated methodology. Biorxiv : the Preprint Server For Biology |
| Zhang R, Fang J, Xie X, et al. (2024) Regulation of urea cycle by reversible high-stoichiometry lysine succinylation. Nature Metabolism |
| Monteith AJ, Ramsey HE, Silver AJ, et al. (2024) Lactate utilization enables metabolic escape to confer resistance to BET inhibition in acute myeloid leukemia. Cancer Research |