Mitchell Guttman, Ph.D.

Affiliations: 
2013- Biology and Biological Engineering California Institute of Technology, Pasadena, CA 
Area:
long non-coding RNA
Website:
https://guttmanlab.caltech.edu/
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"Mitchell Guttman"

Parents

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Eric Lander grad student 2006-2012 MIT (MathTree)

Children

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Colleen A. McHugh post-doc 2013- Caltech (Microtree)
Joanna Jachowicz post-doc 2017-2022 Caltech
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Publications

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Perez AA, Goronzy IN, Blanco MR, et al. (2024) ChIP-DIP maps binding of hundreds of proteins to DNA simultaneously and identifies diverse gene regulatory elements. Nature Genetics
Guo JK, Blanco MR, Guttman M. (2024) PRC2-RNA interactions: Viewpoint from Jimmy K. Guo, Mario R. Blanco, and Mitchell Guttman. Molecular Cell. 84: 3578-3585
Bhat P, Chow A, Emert B, et al. (2024) Genome organization around nuclear speckles drives mRNA splicing efficiency. Nature
Guo JK, Blanco MR, Walkup WG, et al. (2024) Denaturing purifications demonstrate that PRC2 and other widely reported chromatin proteins do not appear to bind directly to RNA in vivo. Molecular Cell
Perez AA, Goronzy IN, Blanco MR, et al. (2023) ChIP-DIP: A multiplexed method for mapping hundreds of proteins to DNA uncovers diverse regulatory elements controlling gene expression. Biorxiv : the Preprint Server For Biology
Wolin E, Guo JK, Blanco MR, et al. (2023) SPIDR: a highly multiplexed method for mapping RNA-protein interactions uncovers a potential mechanism for selective translational suppression upon cellular stress. Biorxiv : the Preprint Server For Biology
Bhat P, Chow A, Emert B, et al. (2023) 3D genome organization around nuclear speckles drives mRNA splicing efficiency. Biorxiv : the Preprint Server For Biology
Mattick JS, Amaral PP, Carninci P, et al. (2023) Long non-coding RNAs: definitions, functions, challenges and recommendations. Nature Reviews. Molecular Cell Biology
Goronzy IN, Quinodoz SA, Jachowicz JW, et al. (2022) Simultaneous mapping of 3D structure and nascent RNAs argues against nuclear compartments that preclude transcription. Cell Reports. 41: 111730
Guo JK, Guttman M. (2022) Regulatory non-coding RNAs: everything is possible, but what is important? Nature Methods. 19: 1156-1159
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