Colleen A. McHugh, Ph.D.
Affiliations: | 2004-2011 | Molecular Microbiology and Immunology | Johns Hopkins University, Baltimore, MD |
| 2018- | Chemistry and Biochemistry | University of California, San Diego, La Jolla, CA |
Area:
Biochemistry, Structural Biology, Microbiology, Molecular BiologyWebsite:
mchughlab.comGoogle:
"Colleen McHugh"Bio:
Parents
Sign in to add mentor| Egbert Hoiczyk | grad student | 2011 | Johns Hopkins | |
| (Identification and characterization of multimeric protein complexes from Myxococcus xanthus.) | ||||
| Mitchell Guttman | post-doc | 2013- | Caltech (Cell Biology Tree) | |
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Publications
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| Hall SD, Tran K, Zhu J, et al. (2025) DUBR non-coding RNA regulates gene expression by affecting AP-1 enhancer accessibility. Functional & Integrative Genomics. 25: 68 |
| Balaji A, Button AC, Hall SD, et al. (2025) The levels of the long non-coding RNA MALAT1 affect cell viability and modulate TDP-43 binding to mRNA in the nucleus. The Journal of Biological Chemistry. 108207 |
| Su T, Trang N, Zhu J, et al. (2024) GRAS1 non-coding RNA protects against DNA damage and cell death by binding and stabilizing NKAP. Biorxiv : the Preprint Server For Biology |
| Button AC, Hall SD, Ashley EL, et al. (2023) Dissection of protein and RNA regions required for SPEN binding to XIST A-repeat RNA. Rna (New York, N.Y.) |
| Trang N, Su T, Hall S, et al. (2023) Streamlined Purification of RNA-Protein Complexes Using UV Cross-Linking and RNA Antisense Purification. Methods in Molecular Biology (Clifton, N.J.). 2666: 213-229 |
| Burnett CA, Wong AT, Vasquez CA, et al. (2022) Examination of the Cell Cycle Dependence of Cytosine and Adenine Base Editors. Frontiers in Genome Editing. 4: 923718 |
| McHugh CA, Guttman M. (2018) RAP-MS: A Method to Identify Proteins that Interact Directly with a Specific RNA Molecule in Cells. Methods in Molecular Biology (Clifton, N.J.). 1649: 473-488 |
| McHugh CA, Chen CK, Chow A, et al. (2015) The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3. Nature. 521: 232-6 |
| McHugh CA, Fontana J, Nemecek D, et al. (2014) A virus capsid-like nanocompartment that stores iron and protects bacteria from oxidative stress. The Embo Journal. 33: 1896-911 |
| McHugh CA, Russell P, Guttman M. (2014) Methods for comprehensive experimental identification of RNA-protein interactions. Genome Biology. 15: 203 |