Peter W. Piper - Publications

Affiliations: 
Biochemistry University College London 

114 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Millson SH, Truman AW, Piper PW. Hsp90 and phosphorylation of the Slt2(Mpk1) MAP kinase activation loop are essential for catalytic, but not non-catalytic, Slt2-mediated transcription in yeast. Cell Stress & Chaperones. PMID 35420390 DOI: 10.1007/s12192-022-01274-0  0.675
2017 Escalante SG, Brightmore JA, Piper PW, Millson SH. UCS protein function is partially restored in the Saccharomyces cerevisiae she4 mutant with expression of the human UNC45-GC, but not UNC45-SM. Cell Stress & Chaperones. PMID 29288355 DOI: 10.1007/S12192-017-0870-1  0.407
2017 Gomez-Escalante S, Piper PW, Millson SH. Mutation of the Ser18 phosphorylation site on the sole Saccharomyces cerevisiae UCS protein, She4, can compromise high-temperature survival. Cell Stress & Chaperones. 22: 135-141. PMID 27888470 DOI: 10.1007/S12192-016-0750-0  0.444
2017 Piper JD, Piper PW. Benzoate and Sorbate Salts: A Systematic Review of the Potential Hazards of These Invaluable Preservatives and the Expanding Spectrum of Clinical Uses for Sodium Benzoate Comprehensive Reviews in Food Science and Food Safety. 16: 868-880. DOI: 10.1111/1541-4337.12284  0.309
2014 Millson SH, Piper PW. Insights from yeast into whether the inhibition of heat shock transcription factor (Hsf1) by rapamycin can prevent the Hsf1 activation that results from treatment with an Hsp90 inhibitor. Oncotarget. 5: 5054-64. PMID 24970820 DOI: 10.18632/Oncotarget.2077  0.497
2014 Millson S, van Oosten-Hawle P, Alkuriji MA, Truman A, Siderius M, Piper PW. Cdc37 engages in stable, S14A mutation-reinforced association with the most atypical member of the yeast kinome, Cdk-activating kinase (Cak1). Cell Stress & Chaperones. 19: 695-703. PMID 24452458 DOI: 10.1007/S12192-014-0497-4  0.658
2012 Piper PW, Millson SH. Spotlight on the microbes that produce heat shock protein 90-targeting antibiotics. Open Biology. 2: 120138. PMID 23271830 DOI: 10.1098/Rsob.120138  0.423
2012 Mollapour M, Piper PW. Activity of the yeast zinc-finger transcription factor War1 is lost with alanine mutation of two putative phosphorylation sites in the activation domain. Yeast (Chichester, England). 29: 39-44. PMID 22113732 DOI: 10.1002/Yea.1915  0.669
2011 Piper PW, Millson SH. Mechanisms of Resistance to Hsp90 Inhibitor Drugs: A Complex Mosaic Emerges. Pharmaceuticals (Basel, Switzerland). 4: 1400-1422. PMID 27721330 DOI: 10.3390/Ph4111400  0.435
2011 Piper PW. Resistance of yeasts to weak organic acid food preservatives. Advances in Applied Microbiology. 77: 97-113. PMID 22050823 DOI: 10.1016/B978-0-12-387044-5.00004-2  0.373
2011 Millson SH, Chua CS, Roe SM, Polier S, Solovieva S, Pearl LH, Sim TS, Prodromou C, Piper PW. Features of the Streptomyces hygroscopicus HtpG reveal how partial geldanamycin resistance can arise with mutation to the ATP binding pocket of a eukaryotic Hsp90. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 3828-37. PMID 21778327 DOI: 10.1096/Fj.11-188821  0.418
2011 Mollapour M, Tsutsumi S, Truman AW, Xu W, Vaughan CK, Beebe K, Konstantinova A, Vourganti S, Panaretou B, Piper PW, Trepel JB, Prodromou C, Pearl LH, Neckers L. Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity. Molecular Cell. 41: 672-81. PMID 21419342 DOI: 10.1016/J.Molcel.2011.02.011  0.769
2010 Vaughan CK, Neckers L, Piper PW. Understanding of the Hsp90 molecular chaperone reaches new heights. Nature Structural & Molecular Biology. 17: 1400-4. PMID 21127511 DOI: 10.1038/Nsmb1210-1400  0.382
2010 Shepherd A, Piper PW. The Fps1p aquaglyceroporin facilitates the use of small aliphatic amides as a nitrogen source by amidase-expressing yeasts. Fems Yeast Research. 10: 527-34. PMID 20491941 DOI: 10.1111/J.1567-1364.2010.00636.X  0.362
2010 Mollapour M, Tsutsumi S, Donnelly AC, Beebe K, Tokita MJ, Lee MJ, Lee S, Morra G, Bourboulia D, Scroggins BT, Colombo G, Blagg BS, Panaretou B, Stetler-Stevenson WG, Trepel JB, ... Piper PW, et al. Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function. Molecular Cell. 37: 333-43. PMID 20159553 DOI: 10.1016/J.Molcel.2010.01.005  0.698
2010 Millson SH, Prodromou C, Piper PW. A simple yeast-based system for analyzing inhibitor resistance in the human cancer drug targets Hsp90alpha/beta. Biochemical Pharmacology. 79: 1581-8. PMID 20138026 DOI: 10.1016/J.Bcp.2010.01.031  0.408
2009 Mollapour M, Shepherd A, Piper PW. Presence of the Fps1p aquaglyceroporin channel is essential for Hog1p activation, but suppresses Slt2(Mpk1)p activation, with acetic acid stress of yeast. Microbiology (Reading, England). 155: 3304-11. PMID 19608606 DOI: 10.1099/Mic.0.030502-0  0.66
2009 Millson SH, Nuttall JM, Mollapour M, Piper PW. The Hsp90/Cdc37p chaperone system is a determinant of molybdate resistance in Saccharomyces cerevisiae. Yeast (Chichester, England). 26: 339-47. PMID 19399909 DOI: 10.1002/Yea.1670  0.693
2009 Prodromou C, Nuttall JM, Millson SH, Roe SM, Sim TS, Tan D, Workman P, Pearl LH, Piper PW. Structural basis of the radicicol resistance displayed by a fungal hsp90. Acs Chemical Biology. 4: 289-97. PMID 19236053 DOI: 10.1021/Cb9000316  0.453
2009 Vaughan CK, Piper PW, Pearl LH, Prodromou C. A common conformationally coupled ATPase mechanism for yeast and human cytoplasmic HSP90s. The Febs Journal. 276: 199-209. PMID 19032597 DOI: 10.1111/J.1742-4658.2008.06773.X  0.423
2008 Vaughan CK, Mollapour M, Smith JR, Truman A, Hu B, Good VM, Panaretou B, Neckers L, Clarke PA, Workman P, Piper PW, Prodromou C, Pearl LH. Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37. Molecular Cell. 31: 886-95. PMID 18922470 DOI: 10.1016/J.Molcel.2008.07.021  0.749
2008 Millson SH, Vaughan CK, Zhai C, Ali MM, Panaretou B, Piper PW, Pearl LH, Prodromou C. Chaperone ligand-discrimination by the TPR-domain protein Tah1. The Biochemical Journal. 413: 261-8. PMID 18412542 DOI: 10.1042/Bj20080105  0.437
2008 Mollapour M, Shepherd A, Piper PW. Novel stress responses facilitate Saccharomyces cerevisiae growth in the presence of the monocarboxylate preservatives. Yeast (Chichester, England). 25: 169-77. PMID 18240334 DOI: 10.1002/Yea.1576  0.658
2007 Millson SH, Truman AW, Rácz A, Hu B, Panaretou B, Nuttall J, Mollapour M, Söti C, Piper PW. Expressed as the sole Hsp90 of yeast, the α and β isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90β generates sensitivity to the Hsp90 inhibitor radicicol Febs Journal. 274: 4453-4463. PMID 17681020 DOI: 10.1111/J.1742-4658.2007.05974.X  0.778
2007 Mollapour M, Piper PW. Hog1 mitogen-activated protein kinase phosphorylation targets the yeast Fps1 aquaglyceroporin for endocytosis, thereby rendering cells resistant to acetic acid. Molecular and Cellular Biology. 27: 6446-56. PMID 17620418 DOI: 10.1128/Mcb.02205-06  0.672
2007 Truman AW, Millson SH, Nuttall JM, Mollapour M, Prodromou C, Piper PW. In the yeast heat shock response, Hsf1-directed induction of Hsp90 facilitates the activation of the Slt2 (Mpk1) mitogen-activated protein kinase required for cell integrity Eukaryotic Cell. 6: 744-752. PMID 17293484 DOI: 10.1128/Ec.00009-07  0.773
2006 Mollapour M, Piper PW. Hog1p mitogen-activated protein kinase determines acetic acid resistance in Saccharomyces cerevisiae. Fems Yeast Research. 6: 1274-80. PMID 17156024 DOI: 10.1111/J.1567-1364.2006.00118.X  0.645
2006 Piper PW, Truman AW, Millson SH, Nuttall J. Hsp90 chaperone control over transcriptional regulation by the yeast slt2(Mpk1)p and human ERK5 mitogen-activated protein kinases (MAPKs) Biochemical Society Transactions. 34: 783-785. PMID 17052197 DOI: 10.1042/Bst0340783  0.471
2006 Phelan JP, Millson SH, Parker PJ, Piper PW, Cooke FT. Fab1p and AP-1 are required for trafficking of endogenously ubiquitylated cargoes to the vacuole lumen in S. cerevisiae. Journal of Cell Science. 119: 4225-34. PMID 17003107 DOI: 10.1242/Jcs.03188  0.345
2006 Truman AW, Millson SH, Nuttall JM, King V, Mollapour M, Prodromou C, Pearl LH, Piper PW. Expressed in the yeast Saccharomyces cerevisiae, human ERK5 is a client of the Hsp90 chaperone that complements loss of the Slt2p (Mpk1p) cell integrity stress-activated protein kinase Eukaryotic Cell. 5: 1914-1924. PMID 16950928 DOI: 10.1128/Ec.00263-06  0.766
2006 Piper PW, Harris NL, MacLean M. Preadaptation to efficient respiratory maintenance is essential both for maximal longevity and the retention of replicative potential in chronologically ageing yeast. Mechanisms of Ageing and Development. 127: 733-40. PMID 16784770 DOI: 10.1016/J.Mad.2006.05.004  0.35
2006 Ali MM, Roe SM, Vaughan CK, Meyer P, Panaretou B, Piper PW, Prodromou C, Pearl LH. Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex. Nature. 440: 1013-7. PMID 16625188 DOI: 10.1038/Nature04716  0.424
2006 Mollapour M, Phelan JP, Millson SH, Piper PW, Cooke FT. Weak acid and alkali stress regulate phosphatidylinositol bisphosphate synthesis in Saccharomyces cerevisiae. The Biochemical Journal. 395: 73-80. PMID 16316315 DOI: 10.1042/Bj20051765  0.633
2005 Millson SH, Truman AW, King V, Prodromou C, Pearl LH, Piper PW. A two-hybrid screen of the yeast proteome for Hsp90 interactors uncovers a novel Hsp90 chaperone requirement in the activity of a stress-activated mitogen-activated protein kinase, Slt2p (Mpk1p) Eukaryotic Cell. 4: 849-860. PMID 15879519 DOI: 10.1128/Ec.4.5.849-860.2005  0.709
2005 Guerra E, Chye PP, Berardi E, Piper PW. Hypoxia abolishes transience of the heat-shock response in the methylotrophic yeast Hansenula polymorpha. Microbiology (Reading, England). 151: 805-11. PMID 15758226 DOI: 10.1099/Mic.0.27272-0  0.379
2005 Hu B, Liao C, Millson SH, Mollapour M, Prodromou C, Pearl LH, Piper PW, Panaretou B. Qri2/Nse4, a component of the essential Smc5/6 DNA repair complex. Molecular Microbiology. 55: 1735-50. PMID 15752197 DOI: 10.1111/J.1365-2958.2005.04531.X  0.614
2005 Harris N, Bachler M, Costa V, Mollapour M, Moradas-Ferreira P, Piper PW. Overexpressed Sod1p acts either to reduce or to increase the lifespans and stress resistance of yeast, depending on whether it is Cu(2+)-deficient or an active Cu,Zn-superoxide dismutase. Aging Cell. 4: 41-52. PMID 15659212 DOI: 10.1111/J.1474-9726.2005.00142.X  0.592
2004 Millson SH, Truman AW, Wolfram F, King V, Panaretou B, Prodromou C, Pearl LH, Piper PW. Investigating the protein-protein interactions of the yeast Hsp90 chaperone system by two-hybrid analysis: Potential uses and limitations of this approach Cell Stress and Chaperones. 9: 359-368. PMID 15633294 DOI: 10.1379/Csc-29R1.1  0.689
2004 Siligardi G, Hu B, Panaretou B, Piper PW, Pearl LH, Prodromou C. Co-chaperone regulation of conformational switching in the Hsp90 ATPase cycle. The Journal of Biological Chemistry. 279: 51989-98. PMID 15466438 DOI: 10.1074/Jbc.M410562200  0.432
2004 Mollapour M, Fong D, Balakrishnan K, Harris N, Thompson S, Schüller C, Kuchler K, Piper PW. Screening the yeast deletant mutant collection for hypersensitivity and hyper-resistance to sorbate, a weak organic acid food preservative. Yeast (Chichester, England). 21: 927-46. PMID 15334557 DOI: 10.1002/Yea.1141  0.646
2004 Meyer P, Prodromou C, Liao C, Hu B, Roe SM, Vaughan CK, Vlasic I, Panaretou B, Piper PW, Pearl LH. Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery. The Embo Journal. 23: 1402-10. PMID 15039704 DOI: 10.1038/Sj.Emboj.7600141  0.412
2004 Meyer P, Prodromou C, Liao C, Hu B, Mark Roe S, Vaughan CK, Vlasic I, Panaretou B, Piper PW, Pearl LH. Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery. The Embo Journal. 23: 511-9. PMID 14739935 DOI: 10.1038/Sj.Emboj.7600060  0.412
2004 Roe SM, Ali MM, Meyer P, Vaughan CK, Panaretou B, Piper PW, Prodromou C, Pearl LH. The Mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50(cdc37). Cell. 116: 87-98. PMID 14718169 DOI: 10.1016/S0092-8674(03)01027-4  0.415
2004 Schüller C, Mamnun YM, Mollapour M, Krapf G, Schuster M, Bauer BE, Piper PW, Kuchler K. Global phenotypic analysis and transcriptional profiling defines the weak acid stress response regulon in Saccharomyces cerevisiae. Molecular Biology of the Cell. 15: 706-20. PMID 14617816 DOI: 10.1091/Mbc.E03-05-0322  0.648
2003 Piper PW, Millson SH, Mollapour M, Panaretou B, Siligardi G, Pearl LH, Prodromou C. Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast. European Journal of Biochemistry. 270: 4689-95. PMID 14622256 DOI: 10.1046/J.1432-1033.2003.03866.X  0.678
2003 Bauer BE, Rossington D, Mollapour M, Mamnun Y, Kuchler K, Piper PW. Weak organic acid stress inhibits aromatic amino acid uptake by yeast, causing a strong influence of amino acid auxotrophies on the phenotypes of membrane transporter mutants. European Journal of Biochemistry. 270: 3189-95. PMID 12869194 DOI: 10.1046/J.1432-1033.2003.03701.X  0.64
2003 Millson SH, Truman AW, Piper PW. Vectors for N- or C-terminal positioning of the yeast Gal4p DNA binding or activator domains Biotechniques. 35: 60-64. PMID 12866406 DOI: 10.2144/03351Bm06  0.649
2003 Harris N, Costa V, MacLean M, Mollapour M, Moradas-Ferreira P, Piper PW. Mnsod overexpression extends the yeast chronological (G(0)) life span but acts independently of Sir2p histone deacetylase to shorten the replicative life span of dividing cells. Free Radical Biology & Medicine. 34: 1599-606. PMID 12788479 DOI: 10.1016/S0891-5849(03)00210-7  0.617
2003 Hatzixanthis K, Mollapour M, Seymour I, Bauer BE, Krapf G, Schüller C, Kuchler K, Piper PW. Moderately lipophilic carboxylate compounds are the selective inducers of the Saccharomyces cerevisiae Pdr12p ATP-binding cassette transporter. Yeast (Chichester, England). 20: 575-85. PMID 12734796 DOI: 10.1002/Yea.981  0.642
2003 Meyer P, Prodromou C, Hu B, Vaughan C, Roe SM, Panaretou B, Piper PW, Pearl LH. Structural and functional analysis of the middle segment of hsp90: implications for ATP hydrolysis and client protein and cochaperone interactions. Molecular Cell. 11: 647-58. PMID 12667448 DOI: 10.1016/S1097-2765(03)00065-0  0.405
2003 Kren A, Mamnun YM, Bauer BE, Schüller C, Wolfger H, Hatzixanthis K, Mollapour M, Gregori C, Piper P, Kuchler K. War1p, a novel transcription factor controlling weak acid stress response in yeast. Molecular and Cellular Biology. 23: 1775-85. PMID 12588995 DOI: 10.1128/Mcb.23.5.1775-1785.2003  0.661
2003 Piper PW, Panaretou B, Millson SH, Truman A, Mollapour M, Pearl LH, Prodromou C. Yeast is selectively hypersensitised to heat shock protein 90 (Hsp90)-targetting drugs with heterologous expression of the human Hsp90beta, a property that can be exploited in screens for new Hsp90 chaperone inhibitors. Gene. 302: 165-70. PMID 12527207 DOI: 10.1016/S0378-1119(02)01102-2  0.76
2002 Piper PW, Jones GW, Bringloe D, Harris N, MacLean M, Mollapour M. The shortened replicative life span of prohibitin mutants of yeast appears to be due to defective mitochondrial segregation in old mother cells. Aging Cell. 1: 149-57. PMID 12882345 DOI: 10.1046/J.1474-9728.2002.00018.X  0.621
2002 Panaretou B, Siligardi G, Meyer P, Maloney A, Sullivan JK, Singh S, Millson SH, Clarke PA, Naaby-Hansen S, Stein R, Cramer R, Mollapour M, Workman P, Piper PW, Pearl LH, et al. Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1. Molecular Cell. 10: 1307-18. PMID 12504007 DOI: 10.1016/S1097-2765(02)00785-2  0.693
2002 Siligardi G, Panaretou B, Meyer P, Singh S, Woolfson DN, Piper PW, Pearl LH, Prodromou C. Regulation of Hsp90 ATPase activity by the co-chaperone Cdc37p/p50cdc37. The Journal of Biological Chemistry. 277: 20151-9. PMID 11916974 DOI: 10.1074/Jbc.M201287200  0.43
2002 Piper PW, Bringloe D. Loss of prohibitins, though it shortens the replicative life span of yeast cells undergoing division, does not shorten the chronological life span of G0-arrested cells. Mechanisms of Ageing and Development. 123: 287-95. PMID 11744041 DOI: 10.1016/S0047-6374(01)00326-8  0.338
2002 Mollapour M, Piper PW. The ZbYME2 gene from the food spoilage yeast Zygosaccharomyces bailii confers not only YME2 functions in Saccharomyces cerevisiae, but also the capacity for catabolism of sorbate and benzoate, two major weak organic acid preservatives. Molecular Microbiology. 42: 919-30. PMID 11737636 DOI: 10.1046/J.1365-2958.2001.02686.X  0.649
2001 Piper P, Calderon CO, Hatzixanthis K, Mollapour M. Weak acid adaptation: the stress response that confers yeasts with resistance to organic acid food preservatives. Microbiology (Reading, England). 147: 2635-2642. PMID 11577142 DOI: 10.1099/00221287-147-10-2635  0.615
2001 Harris N, MacLean M, Hatzianthis K, Panaretou B, Piper PW. Increasing Saccharomyces cerevisiae stress resistance, through the overactivation of the heat shock response resulting from defects in the Hsp90 chaperone, does not extend replicative life span but can be associated with slower chronological ageing of nondividing cells. Molecular Genetics and Genomics : Mgg. 265: 258-63. PMID 11361336 DOI: 10.1007/s004380000409  0.318
2001 MacLean M, Harris N, Piper PW. Chronological lifespan of stationary phase yeast cells; a model for investigating the factors that might influence the ageing of postmitotic tissues in higher organisms. Yeast (Chichester, England). 18: 499-509. PMID 11284006 DOI: 10.1002/Yea.701  0.361
2001 Mollapour M, Piper P. Targeted gene deletion in Zygosaccharomyces bailii. Yeast (Chichester, England). 18: 173-86. PMID 11169759 DOI: 10.1002/1097-0061(20010130)18:2<173::Aid-Yea663>3.0.Co;2-F  0.616
2000 Prodromou C, Panaretou B, Chohan S, Siligardi G, O'Brien R, Ladbury JE, Roe SM, Piper PW, Pearl LH. The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains. The Embo Journal. 19: 4383-92. PMID 10944121 DOI: 10.1093/Emboj/19.16.4383  0.415
2000 Holyoak CD, Thompson S, Ortiz Calderon C, Hatzixanthis K, Bauer B, Kuchler K, Piper PW, Coote PJ. Loss of Cmk1 Ca(2+)-calmodulin-dependent protein kinase in yeast results in constitutive weak organic acid resistance, associated with a post-transcriptional activation of the Pdr12 ATP-binding cassette transporter. Molecular Microbiology. 37: 595-605. PMID 10931353 DOI: 10.1046/J.1365-2958.2000.02017.X  0.474
2000 Piper PW. Yeast superoxide dismutase mutants reveal a pro-oxidant action of weak organic acid food preservatives. Free Radical Biology & Medicine. 27: 1219-27. PMID 10641714 DOI: 10.1016/S0891-5849(99)00147-1  0.32
1999 Panaretou B, Sinclair K, Prodromou C, Johal J, Pearl L, Piper PW. The Hsp90 of Candida albicans can confer Hsp90 functions in Saccharomyces cerevisiae: a potential model for the processes that generate immunogenic fragments of this molecular chaperone in C. albicans infections. Microbiology (Reading, England). 145: 3455-3463. PMID 10627043 DOI: 10.1099/00221287-145-12-3455  0.422
1999 Holyoak CD, Bracey D, Piper PW, Kuchler K, Coote PJ. The Saccharomyces cerevisiae weak-acid-inducible ABC transporter Pdr12 transports fluorescein and preservative anions from the cytosol by an energy-dependent mechanism. Journal of Bacteriology. 181: 4644-52. PMID 10419965 DOI: 10.1128/Jb.181.15.4644-4652.1999  0.348
1999 Seymour IJ, Piper PW. Stress induction of HSP30, the plasma membrane heat shock protein gene of Saccharomyces cerevisiae, appears not to use known stress-regulated transcription factors. Microbiology (Reading, England). 145: 231-239. PMID 10206703 DOI: 10.1099/13500872-145-1-231  0.45
1999 Prodromou C, Siligardi G, O'Brien R, Woolfson DN, Regan L, Panaretou B, Ladbury JE, Piper PW, Pearl LH. Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)-domain co-chaperones. The Embo Journal. 18: 754-62. PMID 9927435 DOI: 10.1093/Emboj/18.3.754  0.432
1999 Roe SM, Prodromou C, O'Brien R, Ladbury JE, Piper PW, Pearl LH. Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin. Journal of Medicinal Chemistry. 42: 260-6. PMID 9925731 DOI: 10.1021/jm980403y  0.312
1999 Cheng L, Moghraby J, Piper PW. Weak organic acid treatment causes a trehalose accumulation in low-pH cultures of Saccharomyces cerevisiae, not displayed by the more preservative-resistant Zygosaccharomyces bailii. Fems Microbiology Letters. 170: 89-95. PMID 9919656 DOI: 10.1111/J.1574-6968.1999.Tb13359.X  0.355
1998 Panaretou B, Prodromou C, Roe SM, O'Brien R, Ladbury JE, Piper PW, Pearl LH. ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo. The Embo Journal. 17: 4829-36. PMID 9707442 DOI: 10.1093/Emboj/17.16.4829  0.464
1998 Piper P, Mahé Y, Thompson S, Pandjaitan R, Holyoak C, Egner R, Mühlbauer M, Coote P, Kuchler K. The pdr12 ABC transporter is required for the development of weak organic acid resistance in yeast. The Embo Journal. 17: 4257-65. PMID 9687494 DOI: 10.1093/Emboj/17.15.4257  0.392
1998 Piper P. Differential role of Hsps and trehalose in stress tolerance. Trends in Microbiology. 6: 43-4. PMID 9507635 DOI: 10.1016/S0966-842X(97)01190-6  0.347
1998 Mager WH, Maurer K, Piper PW. 18 Identifying Stress Genes Methods in Microbiology. 26: 337-349. DOI: 10.1016/S0580-9517(08)70339-8  0.331
1997 Braley R, Piper PW. The C-terminus of yeast plasma membrane H+-ATPase is essential for the regulation of this enzyme by heat shock protein Hsp30, but not for stress activation Febs Letters. 418: 123-126. PMID 9414109 DOI: 10.1016/S0014-5793(97)01359-8  0.447
1997 Piper PW, Ortiz-Calderon C, Holyoak C, Coote P, Cole M. Hsp30, the integral plasma membrane heat shock protein of Saccharomyces cerevisiae, is a stress-inducible regulator of plasma membrane H(+)-ATPase. Cell Stress & Chaperones. 2: 12-24. PMID 9250391 DOI: 10.1379/1466-1268(1997)002<0012:Htipmh>2.3.Co;2  0.443
1997 Prodromou C, Roe SM, O'Brien R, Ladbury JE, Piper PW, Pearl LH. Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone. Cell. 90: 65-75. PMID 9230303 DOI: 10.1016/S0092-8674(00)80314-1  0.411
1997 Prodromou C, Roe SM, Piper PW, Pearl LH. A molecular clamp in the crystal structure of the N-terminal domain of the yeast Hsp90 chaperone. Nature Structural Biology. 4: 477-82. PMID 9187656 DOI: 10.1038/Nsb0697-477  0.37
1997 Hodgetts S, Matthews R, Morrissey G, Mitsutake K, Piper P, Burnie J. Over-expression of Saccharomyces cerevisiae hsp90 enhances the virulence of this yeast in mice. Fems Immunology and Medical Microbiology. 16: 229-34. PMID 9116640 DOI: 10.1111/J.1574-695X.1996.Tb00140.X  0.386
1997 Watt R, Piper PW. UBI4, the polyubiquitin gene of Saccharomyces cerevisiae, is a heat shock gene that is also subject to catabolite derepression control. Molecular & General Genetics : Mgg. 253: 439-47. PMID 9037103 DOI: 10.1007/s004380050341  0.305
1997 Prodromou C, Piper PW, Pearl LH. Expression and crystallization of the yeast Hsp82 chaperone, and preliminary X-ray diffraction studies of the amino-terminal domain. Proteins. 25: 517-22. PMID 8865348 DOI: 10.1002/(Sici)1097-0134(199608)25:4<517::Aid-Prot13>3.0.Co;2-K  0.343
1996 Piper P. Induction of heat shock proteins and thermotolerance. Methods in Molecular Biology (Clifton, N.J.). 53: 313-7. PMID 8924991 DOI: 10.1385/0-89603-319-8:313  0.37
1996 Panaretou B, Piper P. Isolation of yeast plasma membranes. Methods in Molecular Biology (Clifton, N.J.). 53: 117-21. PMID 8924973 DOI: 10.1385/0-89603-319-8:117  0.326
1996 Piper PW. The heat shock and ethanol stress responses of yeast exhibit extensive similarity and functional overlap. Fems Microbiology Letters. 134: 121-7. PMID 8586257 DOI: 10.1111/J.1574-6968.1995.Tb07925.X  0.383
1996 Hodgetts S, Matthews R, Morrissey G, Mitsutake K, Piper P, Burnie J. Research articleOver-expression of Saccharomyces cerevisiae hsp90 enhances the virulence of this yeast in mice Fems Immunology and Medical Microbiology. 16. DOI: 10.1016/S0928-8244(96)00088-0  0.385
1996 Piper PW, Emson C, Jones CE, Cowan DA, Fleming TM, Littlechild JA. Complementation of apgk deletion mutation inSaccharomyces cerevisiae with expression of the phosphoglycerate-kinase gene from the hyperthermophilic ArchaeonSulfolobus solfataricus Current Genetics. 29: 594-596. DOI: 10.1007/S002940050091  0.344
1995 Piper PW, Talreja K, Panaretou B, Moradas-Ferreira P, Byrne K, Praekelt UM, Meacock P, Récnacq M, Boucherie H. Induction of major heat-shock proteins of Saccharomyces cerevisiae, including plasma membrane Hsp30, by ethanol levels above a critical threshold. Microbiology (Reading, England). 3031-8. PMID 7812443 DOI: 10.1099/13500872-140-11-3031  0.39
1995 Chen Y, Piper PW. Consequences of the overexpression of ubiquitin in yeast: elevated tolerances of osmostress, ethanol and canavanine, yet reduced tolerances of cadmium, arsenite and paromomycin. Biochimica Et Biophysica Acta. 1268: 59-64. PMID 7626663 DOI: 10.1016/0167-4889(95)00044-S  0.394
1994 Cheng L, Piper PW. Weak acid preservatives block the heat shock response and heat-shock-element-directed lacZ expression of low pH Saccharomyces cerevisiae cultures, an inhibitory action partially relieved by respiratory deficiency. Microbiology (Reading, England). 1085-96. PMID 8025674 DOI: 10.1099/13500872-140-5-1085  0.384
1994 Chen Y, Pioli D, Piper PW. Overexpression of the gene for polyubiquitin in yeast confers increased secretion of a human leucocyte protease inhibitor. Bio/Technology (Nature Publishing Company). 12: 819-23. PMID 7765022 DOI: 10.1038/Nbt0894-819  0.351
1993 Piper PW. Molecular events associated with acquisition of heat tolerance by the yeast Saccharomyces cerevisiae. Fems Microbiology Reviews. 11: 339-55. PMID 8398211 DOI: 10.1111/J.1574-6976.1993.Tb00005.X  0.435
1993 Cheng L, Kirk N, Piper PW. A small influence of HSP90 levels on the trehalose and heat shock element inductions of the yeast heat shock response. Biochemical and Biophysical Research Communications. 195: 201-7. PMID 8363601 DOI: 10.1006/Bbrc.1993.2030  0.435
1992 Hirst K, Piper PW. Starvation for His-tRNAHis in yeast causes translational arrest without a high level of misincorporation of glutamine at histidine codons. Current Genetics. 21: 177-82. PMID 1563042 DOI: 10.1007/Bf00336838  0.391
1992 Panaretou B, Piper PW. The plasma membrane of yeast acquires a novel heat-shock protein (hsp30) and displays a decline in proton-pumping ATPase levels in response to both heat shock and the entry to stationary phase. European Journal of Biochemistry. 206: 635-40. PMID 1535043 DOI: 10.1111/J.1432-1033.1992.Tb16968.X  0.396
1992 Cheng L, Hirst K, Piper PW. Authentic temperature-regulation of a heat shock gene inserted into yeast on a high copy number vector. Influences of overexpression of HSP90 protein on high temperature growth and thermotolerance. Biochimica Et Biophysica Acta. 1132: 26-34. PMID 1511010 DOI: 10.1016/0167-4781(92)90048-5  0.436
1992 Piper P. Heat shock and development (vol. 17 in a monograph series on results and problems in cell differentiation) Febs Letters. 313: 325-325. DOI: 10.1016/0014-5793(92)81228-E  0.32
1991 Piper P. Interdependence of several heat shock gene activations, cyclic AMP decline and changes at the plasma membrane of Saccharomyces cerevisiae. Antonie Van Leeuwenhoek. 58: 195-201. PMID 2175162 DOI: 10.1007/Bf00548933  0.337
1991 De Virgilio C, Piper P, Boller T, Wiemken A. Acquisition of thermotolerance in Saccharomyces cerevisiae without heat shock protein hsp 104 and in the absence of protein synthesis. Febs Letters. 288: 86-90. PMID 1831771 DOI: 10.1016/0014-5793(91)81008-V  0.419
1991 Kirk N, Piper PW. The determinants of heat-shock element-directed lacZ expression in Saccharomyces cerevisiae. Yeast (Chichester, England). 7: 539-46. PMID 1767585 DOI: 10.1002/Yea.320070602  0.382
1991 Kirk N, Piper PW. Methanol as a convenient inducer of heat shock element-directed heterologous gene expression in yeast Biotechnology Letters. 13: 465-470. DOI: 10.1007/Bf01049201  0.363
1990 Piper PW, Curran BP. When a glycolytic gene on a yeast 2 mu ORI-STB plasmid is made essential for growth its expression level is a major determinant of plasmid copy number. Current Genetics. 17: 119-23. PMID 2182198 DOI: 10.1007/Bf00312855  0.349
1990 Panaretou B, Piper PW. Plasma-membrane ATPase action affects several stress tolerances of Saccharomyces cerevisiae and Schizosaccharomyces pombe as well as the extent and duration of the heat shock response Journal of General Microbiology. 136: 1763-1770. DOI: 10.1099/00221287-136-9-1763  0.424
1989 Piper PW, Stråby KB. Processing of transcripts of a dimeric tRNA gene in yeast uses the nuclease responsible for maturation of the 3' termini upon 5 S and 37 S precursor rRNAs. Febs Letters. 250: 311-6. PMID 2666158 DOI: 10.1016/0014-5793(89)80745-8  0.308
1988 Piper PW, Curran B, Davies MW, Hirst K, Lockheart A, Ogden JE, Stanway CA, Kingsman AJ, Kingsman SM. A heat shock element in the phosphoglycerate kinase gene promoter of yeast. Nucleic Acids Research. 16: 1333-48. PMID 3279391 DOI: 10.1093/Nar/16.4.1333  0.419
1988 Piper PW, Curran B, Davies MW, Hirst K, Lockheart A, Seward K. Catabolite control of the elevation of PGK mRNA levels by heat shock in Saccharomyces cerevisiae. Molecular Microbiology. 2: 353-61. PMID 3041241 DOI: 10.1111/J.1365-2958.1988.Tb00039.X  0.386
1988 Lambert E, Cowan D, Piper PW. Detection of sequences homologous to the highly-conserved HSP70 gene of eukaryotes in thermophilic eubacteria and archaebacteria Fems Microbiology Letters. 56: 157-160. DOI: 10.1111/J.1574-6968.1988.Tb03169.X  0.389
1988 Piper PW, Lockheart A. A temperature-sensitive mutant ofSacchromyces cerevisiaedefective in the specific phosphatase of trehalose biosynthesis Fems Microbiology Letters. 49: 245-250. DOI: 10.1111/J.1574-6968.1988.Tb02724.X  0.313
1987 Piper PW, Curran B, Davies MW, Lockheart A, Reid G. Transcription of the phosphoglycerate kinase gene of Saccharomyces cerevisiae increases when fermentative cultures are stressed by heat-shock. European Journal of Biochemistry. 161: 525-31. PMID 3539592 DOI: 10.1111/J.1432-1033.1986.Tb10474.X  0.402
1987 Piper PW, Curran B, Davies W, Hirst K, Seward K. Saccharomyces cerevisiae mRNA populations of different intrinsic stability in unstressed and heat shocked cells display almost constant m7GpppA:m7GpppG 5'-cap structure ratios. Febs Letters. 220: 177-80. PMID 3301410 DOI: 10.1016/0014-5793(87)80898-0  0.341
1987 Piper PW, Davies MW, Curran B, Lockheart A, Spalding A, Tuite MF. The influence of cell ploidy on the thermotolerance of Saccharomyces cerevisiae Current Genetics. 11: 595-598. DOI: 10.1007/Bf00393921  0.374
1975 Rhodes D, Piper PW, Clark BF. Location of a platinum binding site in the structure of yeast phenylalanine transfer RNA. Journal of Molecular Biology. 89: 469-75. PMID 4613862 DOI: 10.1016/0022-2836(74)90476-8  0.584
1975 Piper PW, Clark BF. The nucleotide sequences of cytoplasmic methionine and valine tRNAs from mouse myeloma cells. Febs Letters. 47: 56-9. PMID 4426398 DOI: 10.1016/0014-5793(74)80425-4  0.598
1974 Piper PW, Clark BF. Primary structure of a mouse myeloma cell initiator transfer RNA. Nature. 247: 516-8. PMID 4818551 DOI: 10.1038/247516A0  0.576
1973 Piper PW, Clark BF. Lack of Tp-psi-p in loop IV of a mammalian initiator transfer RNA. Febs Letters. 30: 265-7. PMID 4735597 DOI: 10.1016/0014-5793(73)80666-0  0.562
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