Kendall W. Nettles, Ph.D.
Affiliations: | University of Chicago, Chicago, IL |
Area:
breast cancer, steroid hormone actionGoogle:
"Kendall Nettles"Mean distance: 9.94 | S | N | B | C | P |
Parents
Sign in to add mentor| Geoffrey L. Greene | grad student | 2003 | Chicago | |
| (Allosteric control of cofactor recruitment by the estrogen receptor.) | ||||
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Publications
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| Min CK, Nwachukwu JC, Hou Y, et al. (2024) Asymmetric Allostery in Estrogen Receptor-α Homodimers Drives Responses to the Ensemble of Estrogens in the Hormonal Milieu. Biorxiv : the Preprint Server For Biology |
| Iii JY, Gomes F, Durbin K, et al. (2023) Native top-down proteomics reveals EGFR-ERα signaling crosstalk in breast cancer cells dissociates NUTF2 dimers to modulate ERα signaling and cell growth. Research Square |
| Tinivella A, Nwachukwu JC, Angeli A, et al. (2022) Design, synthesis, biological evaluation and crystal structure determination of dual modulators of carbonic anhydrases and estrogen receptors. European Journal of Medicinal Chemistry. 246: 115011 |
| Min J, Nwachukwu JC, Min CK, et al. (2021) Dual-mechanism estrogen receptor inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Bruno NE, Nwachukwu JC, Srinivasan S, et al. (2021) Chemical systems biology reveals mechanisms of glucocorticoid receptor signaling. Nature Chemical Biology |
| Laws MJ, Ziegler Y, Shahoei SH, et al. (2020) Suppression of breast cancer metastasis and extension of survival by a new antiestrogen in a preclinical model driven by mutant estrogen receptors. Breast Cancer Research and Treatment |
| Nwachukwu J, Min J, Srinivasan SK, et al. (2020) OR12-07 Full Antagonism of Breast Cancer Cell Proliferation Can Result from Many Ligand-Induced Conformational Distortions of the Estrogen Receptor Ligand Binding Domain Journal of the Endocrine Society. 4 |
| Katzenellenbogen JA, Min J, Srinivasan S, et al. (2020) Abstract P6-04-10: Combining direct and indirect modes of antiestrogen ligand antagonism of estrogen receptor activity in breast cancer Cancer Research. 80 |
| Lo YC, Cormier O, Liu T, et al. (2019) Pocket similarity identifies selective estrogen receptor modulators as microtubule modulators at the taxane site. Nature Communications. 10: 1033 |
| Zhang B, Kiefer JR, Blake RA, et al. (2019) Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha. Bioorganic & Medicinal Chemistry Letters |