Wendi M. David, Ph.D.
Affiliations: | University of Texas at Austin, Austin, Texas, U.S.A. |
Area:
Synthetic Medicinal Chemistry, Nucleic Acids Chemistry, Natural Products Chemistry, Computational ChemistryGoogle:
"Wendi David"Mean distance: 9.25 | S | N | B | C | P |
Parents
Sign in to add mentor| Sean M. Kerwin | grad student | 2000 | UT Austin | |
| (Studies of a new class of aza -enediynes: Aza -Bergman cyclization and the potential use of aza-enediynes as antitumor agents.) | ||||
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Publications
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| Kerwin SM, David WM. (2015) G-quadruplex dynamics: Assays for intramolecular G-quadruplex helicases and inhibitors Biological Relevance and Therapeutic Applications of Dna and Rna Quadruplexes. 85-99 |
| Laroche C, Li J, Gonzales C, et al. (2010) Cyclization kinetics and biological evaluation of an anticancer 1,2-dialkynylimidazole Organic and Biomolecular Chemistry. 8: 1535-1539 |
| Kumar D, David WM, Kerwin SM. (2010) ChemInform Abstract: N-Propargyl-2-alkynylbenzothiazolium Aza-enediynes: Role of the 2-Alkynylbenzothiazolium Functionality in DNA Cleavage. Cheminform. 33: no-no |
| Plyler J, Jasheway K, Tuesuwan B, et al. (2009) Real-time investigation of SV40 large T-antigen helicase activity using surface plasmon resonance. Cell Biochemistry and Biophysics. 53: 43-52 |
| Tuesuwan B, Kern JT, Thomas PW, et al. (2008) Simian virus 40 large T-antigen G-quadruplex DNA helicase inhibition by G-quadruplex DNA-interactive agents Biochemistry. 47: 1896-1909 |
| Nadipuram AK, David WM, Kumar D, et al. (2002) Synthesis and Thermolysis of Heterocyclic 3-Aza-3-ene-1,5-diynes Organic Letters. 4: 4543-4546 |
| David WM, Brodbelt J, Kerwin SM, et al. (2002) Investigation of quadruplex oligonucleotide - Drug interactions by electrospray ionization mass spectrometry Analytical Chemistry. 74: 2029-2033 |
| Tuntiwechapikul W, David WM, Kumar D, et al. (2002) DNA modification by 4-aza-3-ene-1,6-diynes: DNA cleavage, pH-dependent cytosine-specific interactions, and cancer cell cytotoxicity Biochemistry. 41: 5283-5290 |
| David WM, Brodbelt JS. (2002) ESI-MS investigation of quadruplex DNA and quadruplex DNA:Drug interactions Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 421-422 |
| Kumar D, David WM, Kerwin SM. (2001) N-propargyl-2-alkynylbenzothiazolium aza-enediynes: Role of the 2-alkynylbenzothiazolium functionality in DNA cleavage Bioorganic and Medicinal Chemistry Letters. 11: 2971-2974 |