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Roberta F. Colman

Affiliations: 
1973-2009 Chemistry and Biochemistry University of Delaware, Newark, DE, United States 
Area:
enzyme active sites
Website:
http://www.udel.edu/chem/colman/colman.htm
Google:
"Roberta Colman"
Bio:

http://www.udel.edu/chem/burmeister/bhc36/colman.html

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Parents

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Frank H. Westheimer grad student 1962 Harvard
Simon Black post-doc 1962-1964 NIH
Herbert Tabor post-doc 1962-1964 NIH
Carl Frieden post-doc 1964-1966 Washington University

Children

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Rodney A. Bednar grad student 1977-1981 University of Delaware
Marlene Ann Jacobson grad student 1984 University of Delaware
Joseph J. Barycki grad student 1991-1997 University of Delaware
Jibo Wang grad student 2000 University of Delaware
Dione Kampa grad student 2002 University of Delaware
Jennifer B. Palenchar grad student 2003 University of Delaware
Melissa A. Vargo grad student 2004 University of Delaware
Jennifer L. Hearne grad student 2006 University of Delaware
Luis A. Ralat grad student 2008 University of Delaware
Sharmila Sivendran grad student 2008 University of Delaware
Mayura Dange grad student 2010 University of Delaware
Lushanti M. De Zoysa Ariyananda grad student 2010 University of Delaware
Anastasia F. Thevenin grad student 2010 University of Delaware
John Matthew Tomich post-doc University of Delaware
Longqin Hu post-doc 1993-1996 University of Delaware

Collaborators

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BETA: Related publications

Publications

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Thévenin AF, Zony CL, Bahnson BJ, et al. (2011) GST pi modulates JNK activity through a direct interaction with JNK substrate, ATF2. Protein Science : a Publication of the Protein Society. 20: 834-48
De Zoysa Ariyananda L, Antonopoulos C, Currier J, et al. (2011) In vitro hybridization and separation of hybrids of human adenylosuccinate lyase from wild-type and disease-associated mutant enzymes. Biochemistry. 50: 1336-46
Thévenin AF, Zony CL, Bahnson BJ, et al. (2011) Activation by phosphorylation and purification of human c-Jun N-terminal kinase (JNK) isoforms in milligram amounts. Protein Expression and Purification. 75: 138-46
Dange M, Colman RF. (2010) Each conserved active site tyr in the three subunits of human isocitrate dehydrogenase has a different function. The Journal of Biological Chemistry. 285: 20520-5
Ariyananda Lde Z, Lee P, Antonopoulos C, et al. (2009) Biochemical and biophysical analysis of five disease-associated human adenylosuccinate lyase mutants. Biochemistry. 48: 5291-302
Hartong DT, Dange M, McGee TL, et al. (2008) Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle. Nature Genetics. 40: 1230-4
Huang YC, Misquitta S, Blond SY, et al. (2008) Catalytically active monomer of glutathione S-transferase pi and key residues involved in the electrostatic interaction between subunits. The Journal of Biological Chemistry. 283: 32880-8
Sivendran S, Colman RF. (2008) Effect of a new non-cleavable substrate analog on wild-type and serine mutants in the signature sequence of adenylosuccinate lyase of Bacillus subtilis and Homo sapiens. Protein Science : a Publication of the Protein Society. 17: 1162-74
Hung SH, Liu AH, Pixley RA, et al. (2008) A new nonhydrolyzable reactive cGMP analogue, (Rp)-guanosine-3',5'-cyclic-S-(4-bromo-2,3-dioxobutyl)monophosphorothioate, which targets the cGMP binding site of human platelet PDE3A. Bioorganic Chemistry. 36: 141-7
Ralat LA, Misquitta SA, Manevich Y, et al. (2008) Characterization of the complex of glutathione S-transferase pi and 1-cysteine peroxiredoxin. Archives of Biochemistry and Biophysics. 474: 109-18
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