May M. Paing, Ph.D.

Affiliations: 
2005 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmacology
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"May Paing"
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Parents

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JoAnn Trejo grad student 2005 UNC Chapel Hill
 (Regulation of protease -activated receptor-1 signaling and trafficking.)
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Publications

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Salinas ND, Paing MM, Tolia NH. (2014) Critical glycosylated residues in exon three of erythrocyte glycophorin A engage Plasmodium falciparum EBA-175 and define receptor specificity. Mbio. 5: e01606-14
Paing MM, Tolia NH. (2014) Multimeric assembly of host-pathogen adhesion complexes involved in apicomplexan invasion. Plos Pathogens. 10: e1004120
Chen E, Paing MM, Salinas N, et al. (2013) Structural and functional basis for inhibition of erythrocyte invasion by antibodies that target Plasmodium falciparum EBA-175. Plos Pathogens. 9: e1003390
Dores MR, Paing MM, Lin H, et al. (2012) AP-3 regulates PAR1 ubiquitin-independent MVB/lysosomal sorting via an ALIX-mediated pathway. Molecular Biology of the Cell. 23: 3612-23
Dores MR, Chen B, Lin H, et al. (2012) ALIX binds a YPX(3)L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting. The Journal of Cell Biology. 197: 407-19
Russo A, Soh UJ, Paing MM, et al. (2009) Caveolae are required for protease-selective signaling by protease-activated receptor-1. Proceedings of the National Academy of Sciences of the United States of America. 106: 6393-7
Marchese A, Paing MM, Temple BR, et al. (2008) G protein-coupled receptor sorting to endosomes and lysosomes. Annual Review of Pharmacology and Toxicology. 48: 601-29
Paing MM, Johnston CA, Siderovski DP, et al. (2006) Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization. Molecular and Cellular Biology. 26: 3231-42
Stalheim L, Ding Y, Gullapalli A, et al. (2005) Multiple independent functions of arrestins in the regulation of protease-activated receptor-2 signaling and trafficking. Molecular Pharmacology. 67: 78-87
Paing MM, Temple BR, Trejo J. (2004) A tyrosine-based sorting signal regulates intracellular trafficking of protease-activated receptor-1: multiple regulatory mechanisms for agonist-induced G protein-coupled receptor internalization. The Journal of Biological Chemistry. 279: 21938-47
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