Megan L. Matthews, Ph.D.
Affiliations: | 2017- | Chemistry | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Chemical Biology, Analytical Chemistry, Proteomics, EnzymologyGoogle:
"Megan Matthews"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| J. Martin Bollinger | grad student | 2011 | Penn State | |
| Carsten Krebs | grad student | 2011 | Penn State | |
| (Protein control of dioxygen activation, substratehydrogen abstraction, and ligand-radical-transfer outcome in the aliphatic halogenase, SyrB2.) | ||||
| Benjamin F. Cravatt | post-doc | 2011- | Scripps Institute | |
BETA: Related publications
See more...
Publications
|
You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect. |
| Pan J, Wenger ES, Matthews ML, et al. (2019) Evidence for Modulation of Oxygen-Rebound Rate in Control of Outcome by Iron(II)- and 2-Oxoglutarate-Dependent Oxygenases. Journal of the American Chemical Society |
| Blaesi EJ, Palowitch GM, Hu K, et al. (2018) Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosine-derived dihydroxyphenylalanine radical. Proceedings of the National Academy of Sciences of the United States of America |
| Martinie RJ, Pollock CJ, Matthews ML, et al. (2017) Vanadyl as a Stable Structural Mimic of Reactive Ferryl Intermediates in Mononuclear Nonheme-Iron Enzymes. Inorganic Chemistry. 56: 13382-13389 |
| Kornahrens AF, Cognetta AB, Brody DM, et al. (2017) Design of Benzoxathiazin-3-one 1,1-Dioxides as a New Class of Irreversible Serine Hydrolase Inhibitors: Discovery of a Uniquely Selective PNPLA4 Inhibitor. Journal of the American Chemical Society |
| Matthews ML, He L, Horning BD, et al. (2017) Chemoproteomic profiling and discovery of protein electrophiles in human cells. Nature Chemistry. 9: 234-243 |
| Horning BD, Suciu RM, Ghadiri DA, et al. (2016) Chemical Proteomic Profiling of Human Methyltransferases. Journal of the American Chemical Society |
| Srnec M, Wong SD, Matthews ML, et al. (2016) Electronic Structure of the Ferryl Intermediate in the α-Ketoglutarate Dependent Non-Heme Iron Halogenase SyrB2: Contributions to H Atom Abstraction Reactivity. Journal of the American Chemical Society. 138: 5110-22 |
| Bollinger JM, Chang WC, Matthews ML, et al. (2015) Mechanisms of 2-oxoglutarate-dependent oxygenases: The hydroxylation paradigm and beyond Rsc Metallobiology. 2015: 95-122 |
| Rajagopalan S, Wang C, Yu K, et al. (2014) Design of activated serine-containing catalytic triads with atomic-level accuracy. Nature Chemical Biology. 10: 386-91 |
| Matthews ML, Chang WC, Layne AP, et al. (2014) Direct nitration and azidation of aliphatic carbons by an iron-dependent halogenase. Nature Chemical Biology. 10: 209-15 |