Kevin B Dagbay
Affiliations: | University of Massachusetts, Amherst, Amherst, MA |
Area:
Protein Engineering, Cysteine Protease, Drug DiscoveryGoogle:
"Kevin Dagbay"Mean distance: (not calculated yet)
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Publications
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| Jackson JW, Pal A, Coricor G, et al. (2024) An antibody that inhibits TGF-β1 release from latent extracellular matrix complexes attenuates the progression of renal fibrosis. Science Signaling. 17: eadn6052 |
| Martin CJ, Datta A, Littlefield C, et al. (2020) Selective inhibition of TGFβ1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape. Science Translational Medicine. 12 |
| Dagbay KB, Treece E, Streich FC, et al. (2020) Structural basis for specific inhibition of extracellular activation of pro- or latent myostatin by the monoclonal antibody SRK-015. The Journal of Biological Chemistry |
| Okerberg ES, Dagbay KB, Green JL, et al. (2019) Chemoproteomics Using Nucleotide Acyl Phosphates Reveals an ATP-Binding Site at the Dimer Interface of Procaspase-6. Biochemistry |
| Eron SJ, MacPherson DJ, Dagbay KB, et al. (2018) Multiple mechanisms of zinc-mediated inhibition for the apoptotic caspases -3, -6, -7, & -8. Acs Chemical Biology |
| Dagbay KB, Hardy JA. (2017) Multiple proteolytic events in caspase-6 self-activation impact conformations of discrete structural regions. Proceedings of the National Academy of Sciences of the United States of America |
| Dagbay KB, Hill ME, Barrett E, et al. (2017) Tumor-Associated Mutations in Caspase-6 Negatively Impact Catalytic Efficiency. Biochemistry |
| Dagbay KB, Bolik-Coulon N, Savinov SN, et al. (2017) Caspase-6 Undergoes a Distinct Helix-Strand Interconversion Upon Substrate Binding. The Journal of Biological Chemistry |
| Dagbay K, Eron SJ, Serrano BP, et al. (2014) A multipronged approach for compiling a global map of allosteric regulation in the apoptotic caspases. Methods in Enzymology. 544: 215-49 |