Thomas E. Dever

Affiliations: 
Protein Biosynthesis National Institutes of Health, Bethesda, MD 
Area:
Gene Regulation and Development
Website:
http://deverlab.nichd.nih.gov/dever_bio.htm
Google:
"Thomas Edward Dever"
Mean distance: 10.69
 

Parents

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William C. Merrick grad student 1990 Case Western
 (Characterization of eukaryotic protein synthesis factors)
Alan G. Hinnebusch post-doc 1990-1994 NICHD
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Publications

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Grosely R, Alvarado C, Ivanov IP, et al. (2024) eIF1 and eIF5 dynamically control translation start site fidelity. Biorxiv : the Preprint Server For Biology
Dever TE, Ivanov IP, Hinnebusch AG. (2023) Translational regulation by uORFs and start codon selection stringency. Genes & Development. 37: 474-489
Shin BS, Ivanov IP, Kim JR, et al. (2023) eEF2 diphthamide modification restrains spurious frameshifting to maintain translational fidelity. Nucleic Acids Research
Wang J, Shin BS, Alvarado C, et al. (2022) Rapid 40S scanning and its regulation by mRNA structure during eukaryotic translation initiation. Cell. 185: 4474-4487.e17
Lapointe CP, Grosely R, Sokabe M, et al. (2022) eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining. Nature
Ivanov IP, Saba JA, Fan CM, et al. (2022) Evolutionarily conserved inhibitory uORFs sensitize mRNA translation to start codon selection stringency. Proceedings of the National Academy of Sciences of the United States of America. 119
Wang J, Wang J, Shin BS, et al. (2020) Structural basis for the transition from translation initiation to elongation by an 80S-eIF5B complex. Nature Communications. 11: 5003
Dever TE, Ivanov IP, Sachs MS. (2020) Conserved Upstream Open Reading Frame Nascent Peptides that Control Translation. Annual Review of Genetics
Kotzaeridou U, Young-Baird SK, Suckow V, et al. (2020) Novel pathogenic EIF2S3 missense variants causing clinically variable MEHMO syndrome with impaired eIF2γ translational function, and literature review. Clinical Genetics
Young-Baird SK, Lourenço MB, Elder MK, et al. (2019) Suppression of MEHMO Syndrome Mutation in eIF2 by Small Molecule ISRIB. Molecular Cell
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