☰

Rainer Riedl - Publications

Affiliations: 
1998-2000 Scripps Research Institute 
 2001-2008 Eli Lilly & Co 
 2009- Zurich University of Applied Sciences 
Tree Info Similar researchers PubMed Report error

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Bagatella S, Haghayegh Jahromi N, Monney C, Polidori M, Gall FM, Marchionatti E, Serra F, Riedl R, Engelhardt B, Oevermann A. Bovine neutrophil chemotaxis to Listeria monocytogenes in neurolisteriosis depends on microglia-released rather than bacterial factors. Journal of Neuroinflammation. 19: 304. PMID 36527076 DOI: 10.1186/s12974-022-02653-1  0.705
2022 Kiss C, Gall FM, Dreier B, Adams M, Riedl R, Plückthun A, Mittl PRE. Structure of a hydrophobic leucinostatin derivative determined by host lattice display. Acta Crystallographica. Section D, Structural Biology. 78: 1439-1450. PMID 36458615 DOI: 10.1107/S2059798322010762  0.73
2022 Brand M, Bommeli EB, Rütimann M, Lindenmann U, Riedl R. Discovery of a Dual SENP1 and SENP2 Inhibitor. International Journal of Molecular Sciences. 23. PMID 36292935 DOI: 10.3390/ijms232012085  0.765
2022 Sabani B, Brand M, Albert I, Inderbitzin J, Eichenseher F, Schmelcher M, Rohrer J, Riedl R, Lehmann S. A novel surface functionalization platform to prime extracellular vesicles for targeted therapy and diagnostic imaging. Nanomedicine : Nanotechnology, Biology, and Medicine. 102607. PMID 36167305 DOI: 10.1016/j.nano.2022.102607  0.49
2021 Shrestha N, Gall FM, Mathieu C, Hierweger MM, Brügger M, Alves MP, Vesin J, Banfi D, Kalbermatter D, Horvat B, Chambon M, Turcatti G, Fotiadis D, Riedl R, Plattet P. Highly Potent Host-Specific Small-Molecule Inhibitor of Paramyxovirus and Pneumovirus Replication with High Resistance Barrier. Mbio. e0262121. PMID 34724816 DOI: 10.1128/mBio.02621-21  0.736
2021 Fischer T, Riedl R. Paracelsus' legacy in the faunal realm: Drugs deriving from animal toxins. Drug Discovery Today. PMID 34678490 DOI: 10.1016/j.drudis.2021.10.003  0.372
2021 Brand M, Wang L, Agnello S, Gazzola S, Gall FM, Raguž L, Kaiser M, Schmidt RS, Ritschl A, Jelk J, Hemphill A, Mäser P, Bütikofer P, Adams M, Riedl R. Antiprotozoal structure-activity relationships of synthetic leucinostatin derivatives and elucidation of their mode of action. Angewandte Chemie (International Ed. in English). PMID 33730410 DOI: 10.1002/anie.202102153  0.723
2021 Zizzari AT, Pliatsika D, Gall FM, Fischer T, Riedl R. New perspectives in oral peptide delivery. Drug Discovery Today. PMID 33497830 DOI: 10.1016/j.drudis.2021.01.020  0.739
2021 Shrestha N, Gall FM, Vesin J, Chambon M, Turcatti G, Fotiadis D, Riedl R, Plattet P. Antiviral Screen against Canine Distemper Virus-Induced Membrane Fusion Activity. Viruses. 13. PMID 33477492 DOI: 10.3390/v13010128  0.744
2020 Neidhart B, Kowalska M, Valentin JDP, Gall FM, Ren Q, Riedl R, Pot S, Rottmar M. Tissue Inhibitor of Metalloproteinase (TIMP) Peptidomimetic as an Adjunctive Therapy for Infectious Keratitis. Biomacromolecules. PMID 33347749 DOI: 10.1021/acs.biomac.0c01473  0.731
2020 Fischer T, Riedl R. Challenges with matrix metalloproteinase inhibition and future drug discovery avenues. Expert Opinion On Drug Discovery. 1-14. PMID 32921161 DOI: 10.1080/17460441.2020.1819235  0.499
2020 Kalbermatter D, Shrestha N, Gall FM, Wyss M, Riedl R, Plattet P, Fotiadis D. Cryo-EM structure of the prefusion state of canine distemper virus fusion protein ectodomain. Journal of Structural Biology: X. 4: 100021. PMID 32647825 DOI: 10.1016/j.yjsbx.2020.100021  0.734
2020 Lindenmann U, Brand M, Gall F, Frasson D, Hunziker L, Kroslakova I, Sievers M, Riedl R. Discovery of a novel Class of potent and selective non-competitive Sentrin-specific Protease 1 Inhibitors. Chemmedchem. PMID 32083799 DOI: 10.1002/Cmdc.202000067  0.748
2019 Höck S, Riedl R. CyBy: a strongly typed, purely functional framework for chemical data management. Journal of Cheminformatics. 11: 80. PMID 33430953 DOI: 10.1186/S13321-019-0403-2  0.708
2019 Fischer T, Riedl R. Inhibitory Antibodies Designed for Matrix Metalloproteinase Modulation. Molecules (Basel, Switzerland). 24. PMID 31216704 DOI: 10.3390/Molecules24122265  0.493
2019 Fischer T, Gazzola S, Riedl R. Approaching Target Selectivity by De Novo Drug Design. Expert Opinion On Drug Discovery. 1-13. PMID 31179763 DOI: 10.1080/17460441.2019.1615435  0.749
2019 Fischer T, Koulas SM, Tsagkarakou AS, Kyriakis E, Stravodimos GA, Skamnaki VT, Liggri PGV, Zographos SE, Riedl R, Leonidas DD. High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl--acyl-β-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors. Molecules (Basel, Switzerland). 24. PMID 30987252 DOI: 10.3390/Molecules24071322  0.483
2019 Fischer T, Senn N, Riedl R. Design and Structural Evolution of Matrix Metalloproteinase Inhibitors. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30720221 DOI: 10.1002/Chem.201805361  0.701
2019 Gall FM, Hohl D, Frasson D, Wermelinger T, Mittl PRE, Sievers M, Riedl R. Drug design inspired by Nature: Crystallographic detection of auto-tailored protease inhibitor template. Angewandte Chemie (International Ed. in English). PMID 30615822 DOI: 10.1002/Anie.201812348  0.787
2019 Fischer T, Senn N, Riedl R. Frontispiece: Design and Structural Evolution of Matrix Metalloproteinase Inhibitors Chemistry – a European Journal. 25. DOI: 10.1002/Chem.201983461  0.671
2019 Gall FM, Hohl D, Frasson D, Wermelinger T, Mittl PRE, Sievers M, Riedl R. Cover Picture: Drug Design Inspired by Nature: Crystallographic Detection of an Auto‐Tailored Protease Inhibitor Template (Angew. Chem. Int. Ed. 12/2019) Angewandte Chemie International Edition. 58: 3653-3653. DOI: 10.1002/Anie.201901671  0.776
2019 Gall FM, Hohl D, Frasson D, Wermelinger T, Mittl PRE, Sievers M, Riedl R. Titelbild: Von der Natur inspiriertes Wirkstoffdesign: kristallographische Detektion eines selbstgenerierten Inhibitor‐Grundgerüsts (Angew. Chem. 12/2019) Angewandte Chemie. 131: 3691-3691. DOI: 10.1002/Ange.201901671  0.756
2019 Gall FM, Hohl D, Frasson D, Wermelinger T, Mittl PRE, Sievers M, Riedl R. Von der Natur inspiriertes Wirkstoffdesign: kristallographische Detektion eines selbstgenerierten Inhibitor‐Grundgerüsts Angewandte Chemie. 131: 4091-4096. DOI: 10.1002/Ange.201812348  0.755
2019 Agnello S, Brand M, Chellat MF, Gazzola S, Riedl R. Eine strukturelle Evaluierung medizinalchemischer Strategien gegen Wirkstoffresistenzen Angewandte Chemie. 131: 3336-3383. DOI: 10.1002/Ange.201802416  0.707
2018 Kalbermatter D, Shrestha N, Ader-Ebert N, Herren M, Moll P, Plemper RK, Altmann KH, Langedijk JP, Gall F, Lindenmann U, Riedl R, Fotiadis D, Plattet P. Primary Resistance Mechanism of the Canine Distemper Virus Fusion Protein against a Small-Molecule Membrane Fusion Inhibitor. Virus Research. PMID 30296457 DOI: 10.1016/J.Virusres.2018.10.003  0.731
2018 Agnello S, Brand M, Chellat MF, Gazzola S, Riedl R. A Structural View on Medicinal Chemistry Strategies against Drug Resistance. Angewandte Chemie (International Ed. in English). PMID 29846032 DOI: 10.1002/Anie.201802416  0.745
2017 Fischer T, Riedl R. Development of a Non-Hydroxamate Dual Matrix Metalloproteinase (MMP)-7/-13 Inhibitor. Molecules (Basel, Switzerland). 22. PMID 32961647 DOI: 10.3390/Molecules22091548  0.481
2017 Senn N, Ott M, Lanz J, Riedl R. Targeted Polypharmacology: Discovery of a Highly Potent Non-Hydroxamate Dual Matrix Metalloproteinase (MMP)-10/-13 Inhibitor. Journal of Medicinal Chemistry. PMID 28953404 DOI: 10.1021/Acs.Jmedchem.7B01001  0.753
2017 Chellat MF, Riedl R. Pseudouridimycin: the first Nucleoside Analogue that Selectively Inhibits Bacterial RNA Polymerase. Angewandte Chemie (International Ed. in English). PMID 28895263 DOI: 10.1002/Anie.201708133  0.771
2017 Fischer T, Riedl R. Targeted Fluoro Positioning for the Discovery of a Potent and Highly Selective Matrix Metalloproteinase Inhibitor. Chemistryopen. 6: 192-195. PMID 28413749 DOI: 10.1002/Open.201600158  0.533
2017 Fischer T, Riedl R. Targeted Fluoro Positioning for the Discovery of a Potent and Highly Selective Matrix Metalloproteinase Inhibitor. Chemistryopen. 6: 167. PMID 28413746 DOI: 10.1002/open.201700042  0.462
2017 Eid SA, Adams M, Scherer T, Torres-Gómez H, Hackl MT, Kaplanian M, Riedl R, Luger A, Fürnsinn C. Emodin, a compound with putative antidiabetic potential, deteriorates glucose tolerance in rodents. European Journal of Pharmacology. PMID 28108376 DOI: 10.1016/J.Ejphar.2017.01.022  0.726
2017 Fischer T, Riedl R. Cover profile : targeted fluoro positioning for the discovery of a potent and highly selective matrix metalloproteinase inhibitor Chemistryopen. 6: 167. DOI: 10.21256/Zhaw-1688  0.507
2017 Fischer T, Riedl R. Cover Picture: Targeted Fluoro Positioning for the Discovery of a Potent and Highly Selective Matrix Metalloproteinase Inhibitor (ChemistryOpen 2/2017) Chemistryopen. 6: 165-165. DOI: 10.1002/Open.201700043  0.507
2017 Chellat MF, Riedl R. Pseudouridimycin: das erste Nukleosid-Analogon, das bakterielle RNA-Polymerase selektiv inhibiert Angewandte Chemie. 129: 13364-13366. DOI: 10.1002/Ange.201708133  0.737
2016 Chellat MF, Raguž L, Riedl R. Targeting Antibiotic Resistance. Angewandte Chemie (International Ed. in English). PMID 27000559 DOI: 10.1002/Anie.201506818  0.742
2016 Fischer T, Riedl R. Molecular Recognition of the Catalytic Zinc(II) Ion in MMP-13: Structure-Based Evolution of an Allosteric Inhibitor to Dual Binding Mode Inhibitors with Improved Lipophilic Ligand Efficiencies. International Journal of Molecular Sciences. 17. PMID 26938528 DOI: 10.3390/Ijms17030314  0.51
2016 Chellat MF, Raguž L, Riedl R. Antibiotikaresistenzen gezielt überwinden Angewandte Chemie. 128: 6710-6738. DOI: 10.1002/Ange.201506818  0.759
2015 Lanz J, Riedl R. Merging allosteric and active site binding motifs: de novo generation of target selectivity and potency via natural-product-derived fragments. Chemmedchem. 10: 451-4. PMID 25487909 DOI: 10.1002/Cmdc.201402478  0.691
2015 Lanz J, Riedl R. Cover Picture: Merging Allosteric and Active Site Binding Motifs: De novo Generation of Target Selectivity and Potency via Natural-Product-Derived Fragments (ChemMedChem 3/2015) Chemmedchem. 10: 425-425. DOI: 10.1002/Cmdc.201590003  0.671
2013 Fischer T, Riedl R. Strategic targeting of multiple water-mediated interactions: a concise and rational structure-based design approach to potent and selective MMP-13 inhibitors. Chemmedchem. 8: 1457-61, 1572. PMID 23894097 DOI: 10.1002/Cmdc.201300278  0.466
2013 Fischer T, Riedl R. Back Cover: Strategic Targeting of Multiple Water‐Mediated Interactions: A Concise and Rational Structure‐Based Design Approach to Potent and Selective MMP‐13 Inhibitors (ChemMedChem 9/2013) Chemmedchem. 8: 1572-1572. DOI: 10.1002/Cmdc.201390039  0.494
2012 Höck S, Riedl R. chemf: A purely functional chemistry toolkit. Journal of Cheminformatics. 4: 38. PMID 23253942 DOI: 10.1186/1758-2946-4-38  0.698
2002 Supekova L, Pezacki JP, Su AI, Loweth CJ, Riedl R, Geierstanger B, Schultz PG, Wemmer DE. Genomic effects of polyamide/DNA interactions on mRNA expression. Chemistry & Biology. 9: 821-7. PMID 12144926 DOI: 10.1016/S1074-5521(02)00174-6  0.745
2000 Berkessel A, Riedl R. Combinatorial de novo synthesis of catalysts: how much of a hit-structure is needed for activity? Journal of Combinatorial Chemistry. 2: 215-9. PMID 10827924 DOI: 10.1021/Cc990073I  0.495
1998 Riedl R, Tappe R, Berkessel A. Probing the scope of the asymmetric dihydroxylation of polymer-bound olefins. Monitoring of HRMAS NMR allows for reaction control and on-bead measurement of enantiomeric excess Journal of the American Chemical Society. 120: 8994-9000. DOI: 10.1021/Ja980183D  0.474
1997 Berkessel A, Riedl R. Fluorescence Reporters for Phosphodiesterase Activity Angewandte Chemie (International Edition in English). 36: 1481-1483. DOI: 10.1002/Anie.199714811  0.477
1997 Berkessel A, Riedl R. Fluoreszenz-Reporter für Phosphodiesterase-Aktivität Angewandte Chemie. 109: 1518-1520. DOI: 10.1002/Ange.19971091313  0.468
Show low-probability matches.