Lei Jia, Ph.D.
Affiliations: | 1998-2002 | Chemistry | Peking University, Beijing, Beijing Shi, China |
| 2002-2008 | Chemistry | New York University, New York, NY, United States |
Area:
mutagenesis and carcinogenesis; molecular modeling; computational chemistryGoogle:
"Lei Jia"Parents
Sign in to add mentor| Luhua Lai | research assistant | 2001-2002 | Peking University | |
| Suse Broyde | grad student | 2007 | NYU | |
| (Structural and thermodynamic properties of spiroiminodihydantoin damaged DNA.) | ||||
| Nicholas E. Geacintov | grad student | 2002-2007 | NYU (Chemistry Tree) | |
| Robert Shapiro | grad student | 2002-2007 | NYU (Chemistry Tree) | |
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Publications
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| Liu Z, Ding S, Kropachev K, et al. (2015) Correction: Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function. Plos One. 10: e0142068 |
| Broyde S, Wang L, Cai Y, et al. (2011) Covalent polycyclic aromatic hydrocarbon-DNA adducts: Carcinogenicity, structure, and function Current Cancer Research. 6: 181-207 |
| Jia L, Kropachev K, Ding S, et al. (2009) Exploring damage recognition models in prokaryotic nucleotide excision repair with a benzo[a]pyrene-derived lesion in UvrB. Biochemistry. 48: 8948-57 |
| Ding S, Jia L, Durandin A, et al. (2009) Absolute configurations of spiroiminodihydantoin and allantoin stereoisomers: comparison of computed and measured electronic circular dichroism spectra. Chemical Research in Toxicology. 22: 1189-93 |
| Jia L, Geacintov NE, Broyde S. (2008) The N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesions. Nucleic Acids Research. 36: 6571-84 |
| Dimitri A, Jia L, Shafirovich V, et al. (2008) Transcription of DNA containing the 5-guanidino-4-nitroimidazole lesion by human RNA polymerase II and bacteriophage T7 RNA polymerase. Dna Repair. 7: 1276-88 |
| Jia L, Shafirovich V, Geacintov NE, et al. (2007) Lesion specificity in the base excision repair enzyme hNeil1: modeling and dynamics studies. Biochemistry. 46: 5305-14 |
| Durandin A, Jia L, Crean C, et al. (2006) Assignment of absolute configurations of the enantiomeric spiroiminodihydantoin nucleobases by experimental and computational optical rotatory dispersion methods. Chemical Research in Toxicology. 19: 908-13 |
| Jia L, Shafirovich V, Shapiro R, et al. (2006) Flexible 5-guanidino-4-nitroimidazole DNA lesions: structures and thermodynamics. Biochemistry. 45: 6644-55 |
| Jia L, Shafirovich V, Shapiro R, et al. (2005) Structural and thermodynamic features of spiroiminodihydantoin damaged DNA duplexes. Biochemistry. 44: 13342-53 |