James A. Searles, Ph.D.
Affiliations: | 2000 | University of Colorado, Boulder, Boulder, CO, United States |
Area:
Chemical Engineering, PharmacyGoogle:
"James Searles"Parents
Sign in to add mentorTheodore W. Randolph | grad student | 2000 | CU Boulder | |
(Heterogeneity phenomena in pharmaceutical lyophilization.) |
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Publications
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Wang J, Searles JA, Torres E, et al. (2022) IMPACT OF ANNEALING AND CONTROLLED ICE NUCLEATION ON PROPERTIES OF A LYOPHILIZED 50 MG/ML MAB FORMULATION. Journal of Pharmaceutical Sciences |
Nail S, Tchessalov S, Shalaev E, et al. (2017) Recommended Best Practices for Process Monitoring Instrumentation in Pharmaceutical Freeze Drying-2017. Aaps Pharmscitech |
Randolph TW, Searles JA. (2002) Freezing and annealing phenomena in lyophilization: Effect upon primary drying rate, morphology, and heterogeneity American Pharmaceutical Review. 5: 40-46 |
Searles JA, Carpenter JF, Randolph TW. (2001) Annealing to optimize the primary drying rate, reduce freezing-induced drying rate heterogeneity, and determine T(g)' in pharmaceutical lyophilization. Journal of Pharmaceutical Sciences. 90: 872-87 |
Searles JA, Carpenter JF, Randolph TW. (2001) The ice nucleation temperature determines the primary drying rate of lyophilization for samples frozen on a temperature-controlled shelf. Journal of Pharmaceutical Sciences. 90: 860-71 |