James A. Searles, Ph.D.

Affiliations: 
2000 University of Colorado, Boulder, Boulder, CO, United States 
Area:
Chemical Engineering, Pharmacy
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"James Searles"

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Theodore W. Randolph grad student 2000 CU Boulder
 (Heterogeneity phenomena in pharmaceutical lyophilization.)
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Wang J, Searles JA, Torres E, et al. (2022) IMPACT OF ANNEALING AND CONTROLLED ICE NUCLEATION ON PROPERTIES OF A LYOPHILIZED 50 MG/ML MAB FORMULATION. Journal of Pharmaceutical Sciences
Nail S, Tchessalov S, Shalaev E, et al. (2017) Recommended Best Practices for Process Monitoring Instrumentation in Pharmaceutical Freeze Drying-2017. Aaps Pharmscitech
Randolph TW, Searles JA. (2002) Freezing and annealing phenomena in lyophilization: Effect upon primary drying rate, morphology, and heterogeneity American Pharmaceutical Review. 5: 40-46
Searles JA, Carpenter JF, Randolph TW. (2001) Annealing to optimize the primary drying rate, reduce freezing-induced drying rate heterogeneity, and determine T(g)' in pharmaceutical lyophilization. Journal of Pharmaceutical Sciences. 90: 872-87
Searles JA, Carpenter JF, Randolph TW. (2001) The ice nucleation temperature determines the primary drying rate of lyophilization for samples frozen on a temperature-controlled shelf. Journal of Pharmaceutical Sciences. 90: 860-71
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