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Matthew B. Seefeldt, Ph.D.

Affiliations: 
2004 University of Colorado, Boulder, Boulder, CO, United States 
Area:
Chemical Engineering, Pharmaceutical Chemistry, Medical Biophysics, General Biophysics
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"Matthew Seefeldt"
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Theodore W. Randolph grad student 2004 CU Boulder
 (High pressure refolding of protein aggregates: Efficacy and thermodynamics.)

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Seefeldt MB, Rosendahl MS, Cleland JL, et al. (2009) Application of high hydrostatic pressure to dissociate aggregates and refold proteins. Current Pharmaceutical Biotechnology. 10: 447-55
Qoronfleh MW, Hesterberg LK, Seefeldt MB. (2007) Confronting high-throughput protein refolding using high pressure and solution screens. Protein Expression and Purification. 55: 209-24
Seefeldt MB, Crouch C, Kendrick B, et al. (2007) Specific volume and adiabatic compressibility measurements of native and aggregated recombinant human interleukin-1 receptor antagonist: density differences enable pressure-modulated refolding. Biotechnology and Bioengineering. 98: 476-85
Kim YS, Randolph TW, Seefeldt MB, et al. (2006) High-pressure studies on protein aggregates and amyloid fibrils. Methods in Enzymology. 413: 237-53
Seefeldt MB, Kim YS, Tolley KP, et al. (2005) High-pressure studies of aggregation of recombinant human interleukin-1 receptor antagonist: thermodynamics, kinetics, and application to accelerated formulation studies. Protein Science : a Publication of the Protein Society. 14: 2258-66
Hesterberg LK, Seefeldt MB, Carpenter JF, et al. (2005) High-hydrostatic pressure refolding of proteins Genetic Engineering News. 25: 46-47
Seefeldt MB, Webb JN, Carpenter JF, et al. (2005) Enhanced refolding of recombinant proteins using high hydrostatic pressure American Biotechnology Laboratory. 23
Seefeldt MB, Ouyang J, Froland WA, et al. (2004) High-pressure refolding of bikunin: efficacy and thermodynamics. Protein Science : a Publication of the Protein Society. 13: 2639-50
Randolph TW, Seefeldt M, Carpenter JF. (2002) High hydrostatic pressure as a tool to study protein aggregation and amyloidosis. Biochimica Et Biophysica Acta. 1595: 224-34
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