Kvido Stříšovský
Affiliations: | 2005-2011 | MRC Laboratory of Molecular Biology, Cambridge, England, United Kingdom | |
| 2011- | Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences |
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"Kvido Stříšovský"Parents
Sign in to add mentor| Jan Konvalinka | grad student | Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (Chemistry Tree) | |
| Matthew Freeman | post-doc | 2005-2011 | MRC-LMB |
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Publications
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| Bhaduri S, Braza MKE, Stanchev S, et al. (2025) An in vitro platform for the enzymatic characterization of the rhomboid protease RHBDL4. The Journal of Biological Chemistry. 108275 |
| Novotný P, Humpolíčková J, Nováková V, et al. (2024) The zymogenic form of SARS-CoV-2 main protease: A discrete target for drug discovery. The Journal of Biological Chemistry. 108079 |
| Bhaduri S, Braza MKE, Stanchev S, et al. (2024) An platform for the enzymatic characterization of the rhomboid protease RHBDL4. Biorxiv : the Preprint Server For Biology |
| Bach K, Dohnálek J, Škerlová J, et al. (2024) Extensive targeting of chemical space at the prime side of ketoamide inhibitors of rhomboid proteases by branched substituents empowers their selectivity and potency. European Journal of Medicinal Chemistry. 275: 116606 |
| Poláchová E, Bach K, Heuten E, et al. (2022) Chemical Blockage of the Mitochondrial Rhomboid Protease PARL by Novel Ketoamide Inhibitors Reveals Its Role in PINK1/Parkin-Dependent Mitophagy. Journal of Medicinal Chemistry. 66: 251-265 |
| Grieve AG, Yeh YC, Chang YF, et al. (2021) Conformational surveillance of Orai1 by a rhomboid intramembrane protease prevents inappropriate CRAC channel activation. Molecular Cell |
| Gandhi S, Baker RP, Cho S, et al. (2020) Designed Parasite-Selective Rhomboid Inhibitors Block Invasion and Clear Blood-Stage Malaria. Cell Chemical Biology |
| Liu G, Beaton SE, Grieve AG, et al. (2020) Bacterial rhomboid proteases mediate quality control of orphan membrane proteins. The Embo Journal. e102922 |
| Škerle J, Humpolíčková J, Johnson N, et al. (2020) Membrane Protein Dimerization in Cell-Derived Lipid Membranes Measured by FRET with MC Simulations. Biophysical Journal |
| Makukhin N, Havelka V, Poláchová E, et al. (2019) Resolving oxidative damage to methionine by an unexpected membrane-associated stereoselective reductase discovered using chiral fluorescent probes. The Febs Journal. 286: 4024-4035 |