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Paul R. Rosevear

Affiliations: 
University of Cincinnati, Cincinnati, OH 
Area:
Medical Biophysics
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"Paul Rosevear"
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Natosha L. Finley grad student 2005 University of Cincinnati

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Cheng Y, Lindert S, Kekenes-Huskey P, et al. (2014) Computational studies of the effect of the S23D/S24D troponin I mutation on cardiac troponin structural dynamics. Biophysical Journal. 107: 1675-85
Cheng Y, Lindert S, Kekenes-Huskey P, et al. (2014) Exploring How Phosphorylation Influences C-I Interaction and Calcium Sensitivity of Troponin by Molecular Dynamics Simulations Biophysical Journal. 106: 660a
Michalek AJ, Howarth JW, Gulick J, et al. (2013) Phosphorylation modulates the mechanical stability of the cardiac myosin-binding protein C motif. Biophysical Journal. 104: 442-52
Howarth JW, Ramisetti S, Nolan K, et al. (2012) Structural insight into unique cardiac myosin-binding protein-C motif: a partially folded domain. The Journal of Biological Chemistry. 287: 8254-62
Solaro RJ, Rosevear P, Kobayashi T. (2008) The unique functions of cardiac troponin I in the control of cardiac muscle contraction and relaxation. Biochemical and Biophysical Research Communications. 369: 82-7
Sadayappan S, Finley N, Howarth JW, et al. (2008) Role of the acidic N' region of cardiac troponin I in regulating myocardial function. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1246-57
Howarth JW, Meller J, Solaro RJ, et al. (2007) Phosphorylation-dependent conformational transition of the cardiac specific N-extension of troponin I in cardiac troponin. Journal of Molecular Biology. 373: 706-22
Sakthivel S, Finley NL, Rosevear PR, et al. (2005) In vivo and in vitro analysis of cardiac troponin I phosphorylation. The Journal of Biological Chemistry. 280: 703-14
Finley NL, Rosevear PR. (2004) Introduction of negative charge mimicking protein kinase C phosphorylation of cardiac troponin I. Effects on cardiac troponin C. The Journal of Biological Chemistry. 279: 54833-40
Finley NL, Howarth JW, Rosevear PR. (2004) Structure of the Mg2+-loaded C-lobe of cardiac troponin C bound to the N-domain of cardiac troponin I: comparison with the Ca2+-loaded structure. Biochemistry. 43: 11371-9
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