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Natosha L. Finley, Ph.D.

Affiliations: 
2005 University of Cincinnati, Cincinnati, OH 
Area:
Medical Biophysics
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"Natosha Finley"
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Paul R. Rosevear grad student 2005 University of Cincinnati
 (Phosphorylation induced modulation of cardiac troponin conformation.)

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Springer TI, Emerson CC, Johns CW, et al. (2017) Interaction with adenylate cyclase toxin from Bordetella pertussis affects the metal binding properties of calmodulin. Febs Open Bio. 7: 25-34
Kuster DW, Govindan S, Springer TI, et al. (2015) A hypertrophic cardiomyopathy-associated MYBPC3 mutation common in populations of South Asian descent causes contractile dysfunction. The Journal of Biological Chemistry. 290: 5855-67
Springer TI, Goebel E, Hariraju D, et al. (2014) Mutation in the β-hairpin of the Bordetella pertussis adenylate cyclase toxin modulates N-lobe conformation in calmodulin. Biochemical and Biophysical Research Communications. 453: 43-8
Finley NL, Cuperman TI. (2014) Cardiac myosin binding protein-C: a structurally dynamic regulator of myocardial contractility. PflüGers Archiv : European Journal of Physiology. 466: 433-8
Holly A, Cuperman TI, Liber C, et al. (2012) The Effects of C-Terminal Mutations on the Folding of Cardiac Myosin Binding Protein-C Biophysical Journal. 102: 558a
Sadayappan S, Finley N, Howarth JW, et al. (2008) Role of the acidic N' region of cardiac troponin I in regulating myocardial function. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1246-57
Sakthivel S, Finley NL, Rosevear PR, et al. (2005) In vivo and in vitro analysis of cardiac troponin I phosphorylation. The Journal of Biological Chemistry. 280: 703-14
Finley NL, Rosevear PR. (2004) Introduction of negative charge mimicking protein kinase C phosphorylation of cardiac troponin I. Effects on cardiac troponin C. The Journal of Biological Chemistry. 279: 54833-40
Finley NL, Howarth JW, Rosevear PR. (2004) Structure of the Mg2+-loaded C-lobe of cardiac troponin C bound to the N-domain of cardiac troponin I: comparison with the Ca2+-loaded structure. Biochemistry. 43: 11371-9
Rosevear PR, Finley N. (2003) Molecular mechanism of levosimendan action: an update. Journal of Molecular and Cellular Cardiology. 35: 1011-5
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