Meenhard Herlyn, DVM, DSc
Affiliations: | Bioengineering | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Biomedical Engineering, Oncology, Cell BiologyWebsite:
https://wistar.org/our-scientists/meenhard-herlynGoogle:
"Meenhard Herlyn"Bio:
https://en.wikipedia.org/wiki/Meenhard_Herlyn
Parents
Sign in to add mentor| Wallace Clark, Jr. | research scientist | University of Pennsylvania/Wistar Institute | |
| Hilary Koprowski | research scientist | University of Pennsylvania/Wistar Institute (ID Tree) |
Children
Sign in to add trainee| Chelsea C. Pinnix | grad student | 2006 | Penn |
| Gao Zhang | grad student | 2012 | Penn |
BETA: Related publications
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Publications
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| Guo Y, Wang H, Liu S, et al. (2025) Engineered extracellular vesicles with DR5 agonistic scFvs simultaneously target tumor and immunosuppressive stromal cells. Science Advances. 11: eadp9009 |
| Wei S, Du K, Lan H, et al. (2024) A Comprehensive Proteogenomic and Spatial Analysis of Innate and Acquired Resistance of Metastatic Melanoma to Immune Checkpoint Blockade Therapies. Biorxiv : the Preprint Server For Biology |
| Zhang X, Pant SM, Ritch CC, et al. (2024) Cell state dependent effects of Bmal1 on melanoma immunity and tumorigenicity. Nature Communications. 15: 633 |
| Jagirdar K, Portuallo ME, Wei M, et al. (2023) ERK hyperactivation serves as a unified mechanism of escape in intrinsic and acquired CDK4/6 inhibitor resistance in acral lentiginous melanoma. Oncogene |
| Zhang W, Yang J, Wang B, et al. (2023) HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation. Cell Reports. 42: 113352 |
| Kim H, Feng Y, Murad R, et al. (2023) Melanoma-intrinsic NR2F6 activity regulates antitumor immunity. Science Advances. 9: eadf6621 |
| Guo W, Zhong W, Xiao Z, et al. (2023) Tumor-derived Small Extracellular Vesicles Inhibit the Efficacy of CAR T Cells against Solid Tumors. Cancer Research |
| Jain V, Harper SL, Versace AM, et al. (2022) Targeting UGCG overcomes resistance to lysosomal autophagy inhibition. Cancer Discovery |
| Ramirez-Salazar E, Herlyn M, Somasundaram R. (2022) Challenges in the humanized mouse model for cancer: A commentary. Journal of Cancer Biology. 2: 42-43 |
| Stejerean-Todoran I, Zimmermann K, Gibhardt CS, et al. (2022) MCU controls melanoma progression through a redox-controlled phenotype switch. Embo Reports. e54746 |