| Year |
Citation |
Score |
| 2024 |
Zhang Y, Chen F, Balic M, Creighton CJ. An essential gene signature of breast cancer metastasis reveals targetable pathways. Breast Cancer Research : Bcr. 26: 98. PMID 38867323 DOI: 10.1186/s13058-024-01855-0 |
0.401 |
|
| 2024 |
Chen F, Zhang Y, Sedlazeck FJ, Creighton CJ. Germline structural variation globally impacts the cancer transcriptome including disease-relevant genes. Cell Reports. Medicine. 101446. PMID 38442712 DOI: 10.1016/j.xcrm.2024.101446 |
0.344 |
|
| 2024 |
Amara CS, Kami Reddy KR, Yuntao Y, Chan YS, Piyarathna DWB, Dobrolecki LE, Shih DJH, Shi Z, Xu J, Huang S, Ellis MJ, Apolo AB, Ballester LY, Gao J, Hansel DE, ... ... Creighton CJ, et al. The IL6/JAK/STAT3 signaling axis is a therapeutic vulnerability in SMARCB1-deficient bladder cancer. Nature Communications. 15: 1373. PMID 38355560 DOI: 10.1038/s41467-024-45132-2 |
0.315 |
|
| 2023 |
Chen F, Zhang Y, Chandrashekar DS, Varambally S, Creighton CJ. Global impact of somatic structural variation on the cancer proteome. Nature Communications. 14: 5637. PMID 37704602 DOI: 10.1038/s41467-023-41374-8 |
0.341 |
|
| 2023 |
Monsivais D, Parks SE, Chandrashekar DS, Varambally S, Creighton CJ. Using cancer proteomics data to identify gene candidates for therapeutic targeting. Oncotarget. 14: 399-412. PMID 37141409 DOI: 10.18632/oncotarget.28420 |
0.351 |
|
| 2023 |
Zhang Y, Chen F, Creighton CJ. Pan-cancer molecular subtypes of metastasis reveal distinct and evolving transcriptional programs. Cell Reports. Medicine. 100932. PMID 36731467 DOI: 10.1016/j.xcrm.2023.100932 |
0.338 |
|
| 2023 |
Creighton CJ. Gene Expression Profiles in Cancers and Their Therapeutic Implications. Cancer Journal (Sudbury, Mass.). 29: 9-14. PMID 36693152 DOI: 10.1097/PPO.0000000000000638 |
0.367 |
|
| 2022 |
Garcia-Recio S, Hinoue T, Wheeler GL, Kelly BJ, Garrido-Castro AC, Pascual T, De Cubas AA, Xia Y, Felsheim BM, McClure MB, Rajkovic A, Karaesmen E, Smith MA, Fan C, Ericsson PIG, ... ... Creighton CJ, et al. Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis. Nature Cancer. PMID 36585450 DOI: 10.1038/s43018-022-00491-x |
0.339 |
|
| 2022 |
Lin M, Ku AT, Dong J, Yue F, Jiang W, Ibrahim AA, Peng F, Creighton CJ, Nagi C, Gutierrez C, Rosen JM, Zhang XH, Hilsenbeck SG, Chen X, Du YN, et al. STAT5 confers lactogenic properties in breast tumorigenesis and restricts metastatic potential. Oncogene. PMID 36261627 DOI: 10.1038/s41388-022-02500-w |
0.346 |
|
| 2022 |
Si H, Zhao N, Pedroza A, Zaske AM, Rosen JM, Creighton CJ, Roarty K. Noncanonical Wnt/Ror2 signaling regulates cell-matrix adhesion to prompt directional tumor cell invasion in breast cancer. Molecular Biology of the Cell. mbcE22020055. PMID 36001375 DOI: 10.1091/mbc.E22-02-0055 |
0.333 |
|
| 2022 |
Kundu ST, Rodriguez BL, Gibson LA, Warner AN, Perez MG, Bajaj R, Fradette JJ, Class CA, Solis LM, Rojas Alvarez FR, Wistuba II, Diao L, Chen F, Sachdeva M, Wang J, ... ... Creighton CJ, et al. The microRNA-183/96/182 cluster inhibits lung cancer progression and metastasis by inducing an interleukin-2-mediated antitumor CD8 cytotoxic T-cell response. Genes & Development. PMID 35654454 DOI: 10.1101/gad.349321.121 |
0.307 |
|
| 2022 |
Zhang Y, Chen F, Chandrashekar DS, Varambally S, Creighton CJ. Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways. Nature Communications. 13: 2669. PMID 35562349 DOI: 10.1038/s41467-022-30342-3 |
0.369 |
|
| 2022 |
Wang W, Han D, Cai Q, Shen T, Dong B, Lewis MT, Wang R, Meng Y, Zhou W, Yi P, Creighton CJ, Moore DD, Yang F. MAPK4 promotes triple negative breast cancer growth and reduces tumor sensitivity to PI3K blockade. Nature Communications. 13: 245. PMID 35017531 DOI: 10.1038/s41467-021-27921-1 |
0.358 |
|
| 2021 |
Tan X, Banerjee P, Liu X, Yu J, Lee S, Ahn YH, Creighton CJ, Kurie JM. Transcriptional control of a collagen deposition and adhesion process that promotes lung adenocarcinoma growth and metastasis. Jci Insight. PMID 34874914 DOI: 10.1172/jci.insight.153948 |
0.316 |
|
| 2021 |
Zhang Y, Chen F, Pleasance E, Williamson L, Grisdale CJ, Titmuss E, Laskin J, Jones SJM, Cortes-Ciriano I, Marra MA, Creighton CJ. Rearrangement-mediated cis-regulatory alterations in advanced patient tumors reveal interactions with therapy. Cell Reports. 37: 110023. PMID 34788622 DOI: 10.1016/j.celrep.2021.110023 |
0.309 |
|
| 2021 |
Wang Z, Hulsurkar M, Zhuo L, Xu J, Yang H, Naderinezhad S, Wang L, Zhang G, Ai N, Li L, Chang JT, Zhang S, Fazli L, Creighton CJ, Bai F, et al. CKB inhibits epithelial-mesenchymal transition and prostate cancer progression by sequestering and inhibiting AKT activation. Neoplasia (New York, N.Y.). 23: 1147-1165. PMID 34706306 DOI: 10.1016/j.neo.2021.09.005 |
0.342 |
|
| 2021 |
Tan X, Banerjee P, Shi L, Xiao GY, Rodriguez BL, Grzeskowiak CL, Liu X, Yu J, Gibbons DL, Russell WK, Creighton CJ, Kurie JM. p53 loss activates prometastatic secretory vesicle biogenesis in the Golgi. Science Advances. 7. PMID 34144984 DOI: 10.1126/sciadv.abf4885 |
0.318 |
|
| 2021 |
Yue F, Jiang W, Ku AT, Young AIJ, Zhang W, Souto EP, Gao Y, Yu Z, Wang Y, Creighton CJ, Nagi C, Wang T, Hilsenbeck SG, Feng XH, Huang S, et al. A Wnt-Independent LGR4-EGFR Signaling Axis in Cancer Metastasis. Cancer Research. PMID 34099494 DOI: 10.1158/0008-5472.CAN-21-1112 |
0.34 |
|
| 2021 |
Bota-Rabassedas N, Banerjee P, Niu Y, Cao W, Luo J, Xi Y, Tan X, Sheng K, Ahn YH, Lee S, Parra ER, Rodriguez-Canales J, Albritton J, Weiger M, Liu X, ... ... Creighton CJ, et al. Contextual cues from cancer cells govern cancer-associated fibroblast heterogeneity. Cell Reports. 35: 109009. PMID 33882319 DOI: 10.1016/j.celrep.2021.109009 |
0.365 |
|
| 2021 |
Monsivais D, Vasquez YM, Chen F, Zhang Y, Chandrashekar DS, Faver JC, Masand RP, Scheurer ME, Varambally S, Matzuk MM, Creighton CJ. Mass-spectrometry-based proteomic correlates of grade and stage reveal pathways and kinases associated with aggressive human cancers. Oncogene. PMID 33627787 DOI: 10.1038/s41388-021-01681-0 |
0.314 |
|
| 2021 |
Chen F, Zhang Y, Creighton CJ. Systematic identification of non-coding somatic single nucleotide variants associated with altered transcription and DNA methylation in adult and pediatric cancers. Nar Cancer. 3: zcab001. PMID 33554123 DOI: 10.1093/narcan/zcab001 |
0.308 |
|
| 2021 |
Addison JB, Voronkova MA, Fugett JH, Lin CC, Linville NC, Trinh B, Livengood RH, Smolkin MB, Schaller MD, Ruppert JM, Pugacheva EN, Creighton CJ, Ivanov AV. Functional hierarchy and cooperation of EMT master transcription factors in breast cancer metastasis. Molecular Cancer Research : McR. PMID 33500360 DOI: 10.1158/1541-7786.MCR-20-0532 |
0.349 |
|
| 2020 |
Wetendorf M, Li R, Wu SP, Liu J, Creighton CJ, Wang T, Janardhan KS, Willson CJ, Lanz RB, Murphy BD, Lydon JP, DeMayo FJ. Constitutive expression of progesterone receptor isoforms promotes the development of hormone-dependent ovarian neoplasms. Science Signaling. 13. PMID 33023986 DOI: 10.1126/scisignal.aaz9646 |
0.328 |
|
| 2020 |
Tan X, Shi L, Banerjee P, Liu X, Guo HF, Yu J, Bota-Rabassedas N, Rodriguez BL, Gibbons DL, Russell WK, Creighton CJ, Kurie JM. A pro-tumorigenic secretory pathway activated by p53 deficiency in lung adenocarcinoma. The Journal of Clinical Investigation. PMID 32931483 DOI: 10.1172/Jci137186 |
0.368 |
|
| 2020 |
Vykoukal J, Fahrmann JF, Gregg JR, Tang Z, Basourakos S, Irajizad E, Park S, Yang G, Creighton CJ, Fleury A, Mayo J, Paulucci-Holthauzen A, Dennison JB, Murage E, Peterson CB, et al. Caveolin-1-mediated sphingolipid oncometabolism underlies a metabolic vulnerability of prostate cancer. Nature Communications. 11: 4279. PMID 32855410 DOI: 10.1038/S41467-020-17645-Z |
0.399 |
|
| 2020 |
Wang X, Wendel JRH, Emerson RE, Broaddus RR, Creighton CJ, Rusch DB, Buechlein A, DeMayo FJ, Lydon JP, Hawkins SM. Pten and Dicer1 loss in the mouse uterus causes poorly differentiated endometrial adenocarcinoma. Oncogene. PMID 32843721 DOI: 10.1038/S41388-020-01434-5 |
0.477 |
|
| 2020 |
Bajaj R, Kundu ST, Grzeskowiak CL, Fradette JJ, Scott KL, Creighton CJ, Gibbons DL. IMPAD1 and KDELR2 drive invasion and metastasis by enhancing Golgi-mediated secretion. Oncogene. PMID 32753652 DOI: 10.1038/S41388-020-01410-Z |
0.379 |
|
| 2020 |
Kwon OJ, Choi JM, Zhang L, Jia D, Li Z, Zhang Y, Jung SY, Creighton CJ, Xin L. The Sca-1 and Sca-1 mouse prostatic luminal cell lineages are independently sustained. Stem Cells (Dayton, Ohio). PMID 32627901 DOI: 10.1002/Stem.3253 |
0.343 |
|
| 2020 |
Kim O, Park EY, Klinkebiel DL, Pack SD, Shin YH, Abdullaev Z, Emerson RE, Coffey DM, Kwon SY, Creighton CJ, Kwon S, Chang EC, Chiang T, Yatsenko AN, Chien J, et al. In vivo modeling of metastatic human high-grade serous ovarian cancer in mice. Plos Genetics. 16: e1008808. PMID 32497036 DOI: 10.1371/Journal.Pgen.1008808 |
0.413 |
|
| 2020 |
Msaouel P, Malouf GG, Su X, Yao H, Tripathi DN, Soeung M, Gao J, Rao P, Coarfa C, Creighton CJ, Bertocchio JP, Kunnimalaiyaan S, Multani AS, Blando J, He R, et al. Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma. Cancer Cell. PMID 32359397 DOI: 10.1016/J.Ccell.2020.04.002 |
0.331 |
|
| 2020 |
Yuan Y, Ju YS, Kim Y, Li J, Wang Y, Yoon CJ, Yang Y, Martincorena I, Creighton CJ, Weinstein JN, Xu Y, Han L, Kim HL, Nakagawa H, Park K, et al. Publisher Correction: Comprehensive molecular characterization of mitochondrial genomes in human cancers. Nature Genetics. PMID 32047324 DOI: 10.1038/S41588-020-0587-4 |
0.311 |
|
| 2020 |
Calabrese C, Davidson NR, Demircioğlu D, Fonseca NA, He Y, Kahles A, Lehmann KV, Liu F, Shiraishi Y, Soulette CM, Urban L, Greger L, Li S, Liu D, ... ... Creighton CJ, et al. Genomic basis for RNA alterations in cancer. Nature. 578: 129-136. PMID 32025019 DOI: 10.1038/S41586-020-1970-0 |
0.391 |
|
| 2020 |
Yuan Y, Ju YS, Kim Y, Li J, Wang Y, Yoon CJ, Yang Y, Martincorena I, Creighton CJ, Weinstein JN, Xu Y, Han L, Kim HL, Nakagawa H, Park K, et al. Comprehensive molecular characterization of mitochondrial genomes in human cancers. Nature Genetics. PMID 32024997 DOI: 10.1038/S41588-019-0557-X |
0.388 |
|
| 2020 |
Zhang Y, Chen F, Fonseca NA, He Y, Fujita M, Nakagawa H, Zhang Z, Brazma A, Creighton CJ. High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations. Nature Communications. 11: 736. PMID 32024823 DOI: 10.1038/S41467-019-13885-W |
0.415 |
|
| 2020 |
Tan X, Banerjee P, Pham EA, Rutaganira FUN, Basu K, Bota-Rabassedas N, Guo HF, Grzeskowiak CL, Liu X, Yu J, Shi L, Peng DH, Rodriguez BL, Zhang J, Zheng V, ... ... Creighton CJ, et al. PI4KIIIβ is a therapeutic target in chromosome 1q-amplified lung adenocarcinoma. Science Translational Medicine. 12. PMID 31969487 DOI: 10.1126/Scitranslmed.Aax3772 |
0.412 |
|
| 2020 |
Jung K, Park J, Sirupangi T, Jia D, Gandhi N, Pudakalakatti S, Elswood J, Porter W, Putluri N, Zhang XH-, Chen X, Bhattacharya PK, Creighton CJ, Lewis MT, Rosen JM, et al. Abstract P3-06-12: Autophagy-mediated survival mechanism to c-Src inhibitor therapy in triple negative breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P3-06-12 |
0.428 |
|
| 2020 |
King TA, Liu MC, McClure MB, Hinoue T, Kelly BJ, Creighton CJ, Bowen J, Leraas K, Burns RT, Coppens S, Rezk S, Garrett AL, Balko JM, Parker JS, Park BH, et al. Abstract GS3-08: Multiplatform analysis of matched primary and metastatic breast tumors from the AURORA US Network Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-Gs3-08 |
0.439 |
|
| 2019 |
Chen F, Chandrashekar DS, Varambally S, Creighton CJ. Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers. Nature Communications. 10: 5679. PMID 31831737 DOI: 10.1038/S41467-019-13528-0 |
0.441 |
|
| 2019 |
Creighton CJ. Proteomic signatures of clear cell renal cell carcinoma. Nature Reviews. Nephrology. PMID 31780818 DOI: 10.1038/S41581-019-0233-5 |
0.34 |
|
| 2019 |
Manshouri R, Coyaud E, Kundu ST, Peng DH, Stratton SA, Alton K, Bajaj R, Fradette JJ, Minelli R, Peoples MD, Carugo A, Chen F, Bristow C, Kovacs JJ, Barton MC, ... ... Creighton CJ, et al. ZEB1/NuRD complex suppresses TBC1D2b to stimulate E-cadherin internalization and promote metastasis in lung cancer. Nature Communications. 10: 5125. PMID 31719531 DOI: 10.1038/S41467-019-12832-Z |
0.418 |
|
| 2019 |
Thangavel H, Angelis C, Vasaikar S, Bhat R, Jolly MK, Nagi C, Creighton CJ, Chen F, Dobrolecki LE, George JT, Kumar T, Abdulkareem NM, Mao S, Nardone A, Rimawi M, et al. A CTC-Cluster-Specific Signature Derived from OMICS Analysis of Patient-Derived Xenograft Tumors Predicts Outcomes in Basal-Like Breast Cancer. Journal of Clinical Medicine. 8. PMID 31652963 DOI: 10.3390/Jcm8111772 |
0.434 |
|
| 2019 |
Zhang Y, Yang L, Kucherlapati M, Hadjipanayis A, Pantazi A, Bristow CA, Lee EA, Mahadeshwar HS, Tang J, Zhang J, Seth S, Lee S, Ren X, Song X, Sun H, ... ... Creighton CJ, et al. Global impact of somatic structural variation on the DNA methylome of human cancers. Genome Biology. 20: 209. PMID 31610796 DOI: 10.1186/S13059-019-1818-9 |
0.376 |
|
| 2019 |
Fahrmann JF, Vykoukal J, Fleury A, Tripathi S, Dennison JB, Murage E, Wang P, Yu CY, Capello M, Creighton CJ, Do KA, Long JP, Irajizad E, Peterson C, Katayama H, et al. Association between plasma diacetylspermine and tumor spermine synthase with outcome in triple negative breast cancer. Journal of the National Cancer Institute. PMID 31503278 DOI: 10.1093/Jnci/Djz182 |
0.4 |
|
| 2019 |
Thakur VS, Aguila B, Brett-Morris A, Creighton CJ, Welford SM. Spermidine/spermine N1-acetyltransferase 1 is a gene-specific transcriptional regulator that drives brain tumor aggressiveness. Oncogene. PMID 31399646 DOI: 10.1038/S41388-019-0917-0 |
0.407 |
|
| 2019 |
Kim SJ, Garcia-Recio S, Creighton CJ, Perou CM, Rosen JM. Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression. Oncogene. PMID 31289359 DOI: 10.1038/S41388-019-0852-0 |
0.419 |
|
| 2019 |
Liu J, Wang T, Creighton CJ, Wu SP, Ray M, Janardhan KS, Willson CJ, Cho SN, Castro PD, Ittmann MM, Li JL, Davis RJ, DeMayo FJ. JNK represses Lkb-deficiency-induced lung squamous cell carcinoma progression. Nature Communications. 10: 2148. PMID 31089135 DOI: 10.1038/S41467-019-09843-1 |
0.345 |
|
| 2019 |
Monsivais D, Kriseman M, Creighton CJ, Matzuk MM. Reply to Liu et al.: ALK5-mediated tumor suppressor signaling through SMAD2 and SMAD3 in the uterus. Proceedings of the National Academy of Sciences of the United States of America. 116: 9166-9167. PMID 31068478 DOI: 10.1073/Pnas.1904354116 |
0.382 |
|
| 2019 |
Mukhopadhyay UK, Oturkar CC, Adams C, Wickramasekera N, Bansal S, Medisetty R, Miller A, Swetzig WM, Silwal-Pandit L, Borresen-Dale AL, Creighton CJ, Park JH, Konduri SD, Mukhopadhyay A, Caradori A, et al. TP53 Status as a Determinant of Pro- versus Anti-tumorigenic Effects of Estrogen Receptor-beta in Breast Cancer. Journal of the National Cancer Institute. PMID 30990221 DOI: 10.1093/Jnci/Djz051 |
0.357 |
|
| 2019 |
Wei X, Zhang L, Zhou Z, Kwon OJ, Zhang Y, Nguyen H, Dumpit R, True L, Nelson P, Dong B, Xue W, Birchmeier W, Taketo MM, Xu F, Creighton CJ, et al. Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect Mechanisms. Cell Stem Cell. PMID 30982770 DOI: 10.1016/J.Stem.2019.03.010 |
0.325 |
|
| 2019 |
Xu J, Reznik E, Lee HJ, Gundem G, Jonsson P, Sarungbam J, Bialik A, Sanchez-Vega F, Creighton CJ, Hoekstra JG, Zhang L, Sajjakulnukit P, Kremer D, Tolstyka ZP, Casuscelli J, et al. Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma. Elife. 8. PMID 30924768 DOI: 10.7554/Elife.38986 |
0.387 |
|
| 2019 |
Kwon OJ, Zhang Y, Li Y, Wei X, Zhang L, Chen R, Creighton CJ, Xin L. Functional Heterogeneity of Mouse Prostate Stromal Cells Revealed by Single-Cell RNA-Seq. Iscience. 13: 328-338. PMID 30878879 DOI: 10.1016/J.Isci.2019.02.032 |
0.378 |
|
| 2019 |
Wang W, Shen T, Dong B, Creighton CJ, Meng Y, Zhou W, Shi Q, Zhou H, Zhang Y, Moore DD, Yang F. MAPK4 overexpression promotes tumor progression via noncanonical activation of AKT/mTOR signaling. The Journal of Clinical Investigation. PMID 30688659 DOI: 10.1172/Jci97712 |
0.45 |
|
| 2019 |
Kriseman M, Monsivais D, Agno J, Masand RP, Creighton CJ, Matzuk MM. Uterine double-conditional inactivation of and in mice causes endometrial dysregulation, infertility, and uterine cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 30651315 DOI: 10.1073/Pnas.1806862116 |
0.397 |
|
| 2019 |
Bhat R, Qin L, Angelis CD, Sahay D, Bhargava D, Creighton C, Yadav P, Yazdanfard S, Alrawi A, Yadav V, Vasaikar S, Nanda S, Sethunath V, Fu X, Zhang B, et al. Abstract P6-20-10: Role of GPR110 in breast cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-P6-20-10 |
0.365 |
|
| 2019 |
Jung K, Park J, Sirupangi T, Jia D, Gandhi N, Pudakalakatti S, Elswood J, Porter W, Putluri N, Zhang X, Chen X, Bhattacharya P, Creighton C, Lewis M, Rosen J, et al. Abstract P2-02-14: Metabolic regulation and drug resistance in c-Src activated triple negative breast cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P2-02-14 |
0.421 |
|
| 2019 |
Chandrashekar DS, Creighton CJ, Ponce-Rodriguez I, Varambally S. Abstract 2481: Developing analysis platform for pan-cancer study of DNA methylation, mirna and lncrna expression based on tumor subtypes using TCGA data Cancer Research. 79: 2481-2481. DOI: 10.1158/1538-7445.Am2019-2481 |
0.448 |
|
| 2018 |
Chen F, Zhang Y, Varambally S, Creighton CJ. Molecular correlates of metastasis by systematic pan-cancer analysis across The Cancer Genome Atlas. Molecular Cancer Research : McR. PMID 30401717 DOI: 10.1158/1541-7786.Mcr-18-0601 |
0.482 |
|
| 2018 |
Bu W, Liu Z, Jiang W, Nagi C, Huang S, Edwards DP, Jo E, Mo Q, Creighton CJ, Hilsenbeck SG, Leavitt AD, Lewis MT, Wong STC, Li Y. Mammary precancerous stem and non-stem cells evolve into cancers of distinct subtypes. Cancer Research. PMID 30401712 DOI: 10.1158/0008-5472.Can-18-1087 |
0.425 |
|
| 2018 |
Wang Y, Xu X, Maglic D, Dill MT, Mojumdar K, Ng PK, Jeong KJ, Tsang YH, Moreno D, Bhavana VH, Peng X, Ge Z, Chen H, Li J, Chen Z, ... ... Creighton CJ, et al. Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer. Cell Reports. 25: 1304-1317.e5. PMID 30380420 DOI: 10.1016/J.Celrep.2018.10.001 |
0.481 |
|
| 2018 |
Suer I, Guzel E, Karatas OF, Creighton CJ, Ittmann M, Ozen M. MicroRNAs as prognostic markers in prostate cancer. The Prostate. PMID 30345533 DOI: 10.1002/Pros.23731 |
0.358 |
|
| 2018 |
Classe M, Yao H, Mouawad R, Creighton CJ, Burgess A, Allanic F, Wassef M, Leroy X, Verillaud B, Mortuaire G, Bielle F, Le Tourneau C, Kurtz JE, Khayat D, Su X, et al. Integrated Multi-omic Analysis of Esthesioneuroblastomas Identifies Two Subgroups Linked to Cell Ontogeny. Cell Reports. 25: 811-821.e5. PMID 30332658 DOI: 10.1016/J.Celrep.2018.09.047 |
0.366 |
|
| 2018 |
Lu Y, Cao J, Napoli M, Xia Z, Zhao N, Creighton CJ, Li W, Chen X, Flores ER, McManus MT, Rosen JM. MiR-205 Regulates Basal Cell Identity and Stem Cell Regenerative Potential during Mammary Reconstitution. Stem Cells (Dayton, Ohio). PMID 30267595 DOI: 10.1002/Stem.2914 |
0.33 |
|
| 2018 |
Lei JT, Shao J, Zhang J, Iglesia M, Chan DW, Cao J, Anurag M, Singh P, He X, Kosaka Y, Matsunuma R, Crowder R, Hoog J, Phommaly C, Goncalves R, ... ... Creighton CJ, et al. Functional Annotation of ESR1 Gene Fusions in Estrogen Receptor-Positive Breast Cancer. Cell Reports. 24: 1434-1444.e7. PMID 30089255 DOI: 10.1016/J.Celrep.2018.07.009 |
0.402 |
|
| 2018 |
Kundu ST, Grzeskowiak CL, Fradette JJ, Gibson LA, Rodriguez LB, Creighton CJ, Scott KL, Gibbons DL. TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins. Nature Communications. 9: 2731. PMID 30013069 DOI: 10.1038/S41467-018-05013-X |
0.438 |
|
| 2018 |
Grzeskowiak CL, Kundu ST, Mo X, Ivanov AA, Zagorodna O, Lu H, Chapple RH, Tsang YH, Moreno D, Mosqueda M, Eterovic K, Fradette JJ, Ahmad S, Chen F, Chong Z, ... ... Creighton CJ, et al. In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer. Nature Communications. 9: 2732. PMID 30013058 DOI: 10.1038/S41467-018-04572-3 |
0.389 |
|
| 2018 |
Zhang Y, Yang L, Kucherlapati M, Chen F, Hadjipanayis A, Pantazi A, Bristow CA, Lee EA, Mahadeshwar HS, Tang J, Zhang J, Seth S, Lee S, Ren X, Song X, ... ... Creighton CJ, et al. A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases. Cell Reports. 24: 515-527. PMID 29996110 DOI: 10.1016/J.Celrep.2018.06.025 |
0.429 |
|
| 2018 |
Reddy JP, Atkinson RL, Larson R, Burks JK, Smith D, Debeb BG, Ruffell B, Creighton CJ, Bambhroliya A, Reuben JM, Van Laere SJ, Krishnamurthy S, Symmans WF, Brewster AM, Woodward WA. Mammary stem cell and macrophage markers are enriched in normal tissue adjacent to inflammatory breast cancer. Breast Cancer Research and Treatment. PMID 29858753 DOI: 10.1007/S10549-018-4835-6 |
0.389 |
|
| 2018 |
You R, DeMayo FJ, Liu J, Cho SN, Burt BM, Creighton CJ, Casal RF, Lazarus DR, Lu W, Tung HY, Yuan X, Hill AA, Kim M, Perusich S, Cornwell LD, et al. IL17A Regulates Tumor Latency and Metastasis in Lung Adeno and Squamous SQ.2b and AD.1 Cancer. Cancer Immunology Research. PMID 29653981 DOI: 10.1158/2326-6066.Cir-17-0554 |
0.408 |
|
| 2018 |
Campbell JD, Yau C, Bowlby R, Liu Y, Brennan K, Fan H, Taylor AM, Wang C, Walter V, Akbani R, Byers LA, Creighton CJ, Coarfa C, Shih J, Cherniack AD, et al. Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. Cell Reports. 23: 194-212.e6. PMID 29617660 DOI: 10.1016/J.Celrep.2018.03.063 |
0.367 |
|
| 2018 |
Palaniappan M, Edwards D, Creighton CJ, Medina D, Conneely OM. Reprogramming of the estrogen responsive transcriptome contributes to tamoxifen-dependent protection against tumorigenesis in the p53 null mammary epithelial cells. Plos One. 13: e0194913. PMID 29590203 DOI: 10.1371/Journal.Pone.0194913 |
0.49 |
|
| 2018 |
Shao L, Wang J, Karatas OF, Feng S, Zhang Y, Creighton CJ, Ittmann M. Fibroblast growth factor receptor signaling plays a key role in transformation induced by the TMPRSS2/ERG fusion gene and decreased PTEN. Oncotarget. 9: 14456-14471. PMID 29581856 DOI: 10.18632/Oncotarget.24470 |
0.425 |
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| 2018 |
Nair A, Chung HC, Sun T, Tyagi S, Dobrolecki LE, Dominguez-Vidana R, Kurley SJ, Orellana M, Renwick A, Henke DM, Katsonis P, Schmitt E, Chan DW, Li H, Mao S, ... ... Creighton CJ, et al. Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer. Nature Medicine. PMID 29578538 DOI: 10.1038/Nm.4507 |
0.413 |
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| 2018 |
Bhat RR, Yadav P, Sahay D, Bhargava DK, Creighton CJ, Yazdanfard S, Al-Rawi A, Yadav V, Qin L, Nanda S, Sethunath V, Fu X, De Angelis C, Narkar VA, Osborne CK, et al. GPCRs profiling and identification of GPR110 as a potential new target in HER2+ breast cancer. Breast Cancer Research and Treatment. PMID 29574636 DOI: 10.1007/S10549-018-4751-9 |
0.403 |
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| 2018 |
Danussi C, Bose P, Parthasarathy PT, Silberman PC, Van Arnam JS, Vitucci M, Tang OY, Heguy A, Wang Y, Chan TA, Riggins GJ, Sulman EP, Lang F, Creighton CJ, Deneen B, et al. Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling. Nature Communications. 9: 1057. PMID 29535300 DOI: 10.1038/S41467-018-03476-6 |
0.369 |
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| 2018 |
Yu-Lee LY, Yu G, Lee YC, Lin SC, Pan J, Pan T, Yu KJ, Liu B, Creighton CJ, Rodriguez-Canales J, Villalobos PA, Wistuba II, de Nadal E, Posas F, Gallick GE, et al. Osteoblast-secreted factors mediate dormancy of metastatic prostate cancer in the bone via activation of the TGFβRIII-p38MAPK-pS249/T252RB pathway. Cancer Research. PMID 29514796 DOI: 10.1158/0008-5472.Can-17-1051 |
0.378 |
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| 2018 |
Creighton CJ, Chen F, Zhang Y, Gibbons DL, Deneen B, Kwiatkowski D, Ittmann M. Pan-cancer molecular classes transcending tumor lineage across 32 cancer types, multiple data platforms, and over 10,000 cases. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29440175 DOI: 10.1158/1078-0432.Ccr-17-3378 |
0.425 |
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| 2018 |
Reznik E, Luna A, Aksoy BA, Liu EM, La K, Ostrovnaya I, Creighton CJ, Hakimi AA, Sander C. A Landscape of Metabolic Variation across Tumor Types. Cell Systems. PMID 29396322 DOI: 10.1016/J.Cels.2017.12.014 |
0.383 |
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| 2018 |
Tan X, Banerjee P, Liu X, Yu J, Gibbons DL, Wu P, Scott KL, Diao L, Zheng X, Wang J, Jalali A, Suraokar M, Fujimoto J, Behrens C, Liu X, ... ... Creighton CJ, et al. The epithelial-to-mesenchymal transition activator ZEB1 initiates a prometastatic competing endogenous RNA network. The Journal of Clinical Investigation. PMID 29324442 DOI: 10.1172/Jci97225 |
0.361 |
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| 2018 |
Lei J, Shao J, Zhang J, Iglesia M, Chan D, Cao J, Anurag M, Singh P, Haricharan S, Kavuri S, Matsunuma R, Schmidt C, Kosaka Y, Crowder R, Hoog J, ... ... Creighton C, et al. Abstract PD8-03: ESR1 gene fusions drive endocrine therapy resistance and metastasis in breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-Pd8-03 |
0.462 |
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| 2018 |
Jung KH, Park JH, Sirupangi T, Jia D, Pudakalakatti S, Gandhi N, Elswood J, Putluri V, Creighton CJ, Porter W, Lewis MT, Chen X, Putluri N, Bhattacharya PK, Wong LC, et al. Abstract 1331: Inhibition of mitochondrial reprogramming regulated c-Src in triple-negative breast cancer activates autophagy-mediated survival mechanism Cancer Research. 78: 1331-1331. DOI: 10.1158/1538-7445.Am2018-1331 |
0.409 |
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| 2017 |
Hsieh JJ, Le V, Cao D, Cheng EH, Creighton CJ. Genomic classifications of renal cell carcinoma: a critical step towards the future application of personalized kidney cancer care with pan-omics precision. The Journal of Pathology. PMID 29266437 DOI: 10.1002/Path.5022 |
0.362 |
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| 2017 |
El-Shennawy L, Dubrovskyi O, Kastrati I, Danes JM, Zhang Y, Whiteley HE, Creighton CJ, Frasor J. Coactivation of estrogen receptor and IKK-β induces a dormant metastatic phenotype in ER-positive breast cancer. Cancer Research. PMID 29229606 DOI: 10.1158/0008-5472.Can-17-1686 |
0.463 |
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| 2017 |
Coarfa C, Florentin D, Putluri N, Ding Y, Au J, He D, Ragheb A, Frolov A, Michailidis G, Lee M, Kadmon D, Miles B, Smith C, Ittmann M, Rowley D, ... ... Creighton CJ, et al. Influence of the neural microenvironment on prostate cancer. The Prostate. PMID 29131367 DOI: 10.1002/Pros.23454 |
0.341 |
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| 2017 |
Sreekumar A, Toneff MJ, Toh E, Roarty K, Creighton CJ, Belka GK, Lee DK, Xu J, Chodosh LA, Richards JS, Rosen JM. WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis. Developmental Cell. PMID 29103953 DOI: 10.1016/J.Devcel.2017.10.007 |
0.378 |
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| 2017 |
Zhu W, Krishna S, Garcia C, Lin CJ, Mitchell BD, Scott KL, Mohila CA, Creighton CJ, Yoo SH, Lee HK, Deneen B. Daam2 driven degradation of VHL promotes gliomagenesis. Elife. 6. PMID 29053101 DOI: 10.7554/Elife.31926 |
0.464 |
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| 2017 |
Karatas OF, Wang J, Shao L, Ozen M, Zhang Y, Creighton CJ, Ittmann M. miR-33a is a tumor suppressor microRNA that is decreased in prostate cancer. Oncotarget. 8: 60243-60256. PMID 28947967 DOI: 10.18632/Oncotarget.19521 |
0.384 |
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| 2017 |
Glasgow SM, Carlson JC, Zhu W, Chaboub LS, Kang P, Lee HK, Clovis YM, Lozzi BE, McEvilly RJ, Rosenfeld MG, Creighton CJ, Lee SK, Mohila CA, Deneen B. Glia-specific enhancers and chromatin structure regulate NFIA expression and glioma tumorigenesis. Nature Neuroscience. PMID 28892058 DOI: 10.1038/Nn.4638 |
0.344 |
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| 2017 |
Carron EC, Homra S, Rosenberg J, Coffelt SB, Kittrell F, Zhang Y, Creighton CJ, Fuqua SA, Medina D, Machado HL. Macrophages promote the progression of premalignant mammary lesions to invasive cancer. Oncotarget. 8: 50731-50746. PMID 28881599 DOI: 10.18632/Oncotarget.14913 |
0.391 |
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| 2017 |
Chen F, Zhang Y, Bossé D, Lalani AA, Hakimi AA, Hsieh JJ, Choueiri TK, Gibbons DL, Ittmann M, Creighton CJ. Pan-urologic cancer genomic subtypes that transcend tissue of origin. Nature Communications. 8: 199. PMID 28775315 DOI: 10.1038/S41467-017-00289-X |
0.446 |
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| 2017 |
Schliekelman MJ, Creighton CJ, Baird BN, Chen Y, Banerjee P, Bota-Rabassedas N, Ahn YH, Roybal JD, Chen F, Zhang Y, Mishra DK, Kim MP, Liu X, Mino B, Villalobos P, et al. Thy-1(+) Cancer-associated Fibroblasts Adversely Impact Lung Cancer Prognosis. Scientific Reports. 7: 6478. PMID 28744021 DOI: 10.1038/S41598-017-06922-5 |
0.399 |
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| 2017 |
Chandrashekar DS, Bashel B, Balasubramanya SAH, Creighton CJ, Ponce-Rodriguez I, Chakravarthi BVSK, Varambally S. UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses. Neoplasia (New York, N.Y.). 19: 649-658. PMID 28732212 DOI: 10.1016/J.Neo.2017.05.002 |
0.455 |
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| 2017 |
Wang Z, Kim TB, Peng B, Karam JA, Creighton CJ, Joon AY, Kawakami F, Trevisan P, Jonasch E, Chow CW, Rodriguez-Canales J, Tamboli P, Tannir NM, Wood CG, Monzon FA, et al. Sarcomatoid renal cell carcinoma has a distinct molecular pathogenesis, driver mutation profile and transcriptional landscape. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28710314 DOI: 10.1158/1078-0432.Ccr-17-1057 |
0.342 |
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| 2017 |
Roarty K, Pfefferle AD, Creighton CJ, Perou CM, Rosen JM. Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression. Oncogene. 36: 5958-5968. PMID 28650466 DOI: 10.1038/Onc.2017.206 |
0.461 |
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| 2017 |
Casuscelli J, Weinhold N, Gundem G, Wang L, Zabor EC, Drill E, Wang PI, Nanjangud GJ, Redzematovic A, Nargund AM, Manley BJ, Arcila ME, Donin NM, Cheville JC, Thompson RH, ... ... Creighton CJ, et al. Genomic landscape and evolution of metastatic chromophobe renal cell carcinoma. Jci Insight. 2. PMID 28614790 DOI: 10.1172/Jci.Insight.92688 |
0.353 |
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| 2017 |
Wang Y, Wang J, Zhang L, Karatas OF, Shao LJ, Zhang Y, Castro P, Creighton CJ, Ittmann M. RGS12 is a novel tumor suppressor gene in African American prostate cancer that represses AKT and MNX1 expression. Cancer Research. PMID 28611045 DOI: 10.1158/0008-5472.Can-17-0669 |
0.446 |
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| 2017 |
Croce CM, Casadei L, Calore F, Creighton CJ, Guescini M, Batte K, Iwenofu OH, Zewdu A, Braggio D, Bill KL, Fadda P, Lovat F, Lopez G, Gasparini P, Chen JL, et al. Exosome-derived miR-25-3p and miR-92a-3p stimulate liposarcoma progression. Cancer Research. PMID 28588009 DOI: 10.1158/0008-5472.Can-16-2984 |
0.302 |
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| 2017 |
Zhang Y, Kwok-Shing Ng P, Kucherlapati M, Chen F, Liu Y, Tsang YH, de Velasco G, Jeong KJ, Akbani R, Hadjipanayis A, Pantazi A, Bristow CA, Lee E, Mahadeshwar HS, Tang J, ... ... Creighton CJ, et al. A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations. Cancer Cell. PMID 28528867 DOI: 10.1016/J.Ccell.2017.04.013 |
0.402 |
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| 2017 |
Lu H, Villafane N, Dogruluk T, Grzeskowiak CL, Kong K, Tsang YH, Zagorodna O, Pantazi A, Yang L, Neill NJ, Kim YW, Creighton CJ, Verhaak RG, Mills GB, Park P, et al. Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer. Cancer Research. PMID 28512244 DOI: 10.1158/0008-5472.Can-16-2745 |
0.367 |
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| 2017 |
Wang W, Meng Y, Dong B, Dong J, Ittmann MM, Creighton CJ, Yang L, Zhang H, Shen T, Wang J, Rowley DR, Li Y, Chen F, Moore DD, Yang F. A Versatile Tumor Gene Deletion System Reveals a Crucial Role for FGFR1 in Breast Cancer Metastasis. Neoplasia (New York, N.Y.). 19: 421-428. PMID 28433771 DOI: 10.1016/J.Neo.2017.03.003 |
0.469 |
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| 2017 |
Nargund AM, Pham CG, Dong Y, Wang PI, Osmangeyoglu HU, Xie Y, Aras O, Han S, Oyama T, Takeda S, Ray CE, Dong Z, Berge M, Hakimi AA, Monette S, ... ... Creighton CJ, et al. The SWI/SNF Protein PBRM1 Restrains VHL-Loss-Driven Clear Cell Renal Cell Carcinoma. Cell Reports. 18: 2893-2906. PMID 28329682 DOI: 10.1016/J.Celrep.2017.02.074 |
0.352 |
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| 2017 |
Wetendorf M, Wu SP, Wang X, Creighton CJ, Wang T, Lanz RB, Blok L, Tsai SY, Tsai MJ, Lydon JP, DeMayo FJ. Decreased epithelial progesterone receptor A at the window of receptivity is required for preparation of the endometrium for embryo attachment†. Biology of Reproduction. 96: 313-326. PMID 28203817 DOI: 10.1095/Biolreprod.116.144410 |
0.322 |
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| 2017 |
John Lin CC, Yu K, Hatcher A, Huang TW, Lee HK, Carlson J, Weston MC, Chen F, Zhang Y, Zhu W, Mohila CA, Ahmed N, Patel AJ, Arenkiel BR, Noebels JL, ... Creighton CJ, et al. Identification of diverse astrocyte populations and their malignant analogs. Nature Neuroscience. PMID 28166219 DOI: 10.1038/Nn.4493 |
0.313 |
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| 2017 |
Gibbons DL, Creighton CJ. Pan-cancer survey of epithelial-mesenchymal transition markers across The Cancer Genome Atlas. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 28073171 DOI: 10.1002/dvdy.24485 |
0.324 |
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| 2017 |
Ellis MJ, Suman VJ, Hoog J, Goncalves R, Sanati S, Creighton CJ, DeSchryver K, Crouch E, Brink A, Watson M, Luo J, Tao Y, Barnes M, Dowsett M, Budd GT, et al. Ki67 Proliferation Index as a Tool for Chemotherapy Decisions During and After Neoadjuvant Aromatase Inhibitor Treatment of Breast Cancer: Results From the American College of Surgeons Oncology Group Z1031 Trial (Alliance). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016694406. PMID 28045625 DOI: 10.1200/Jco.2016.69.4406 |
0.351 |
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| 2017 |
Fu X, Pereira R, Zhao D, Jung S, Jeselsohn R, Creighton C, Shea M, Nardone A, Angelis C, Tsimelzon A, Wang T, Gutierrez C, Huang S, Edwards D, Rimawi M, et al. Abstract PD2-04: FOXA1 induces a pro-metastatic secretome through ER-dependent and independent transcriptional reprogramming in endocrine-resistant breast cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-Pd2-04 |
0.352 |
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| 2017 |
Lei J, Shao J, Zhang J, Iglesia M, Cao J, Chan D, He X, Kosaka Y, Schmidt C, Matsunuma R, Haricharan S, Crowder R, Hoog J, Phommaly C, Goncalves R, ... ... Creighton C, et al. Abstract PD2-03: Recurrent functionally diverse in-frameESR1gene fusions drive endocrine resistance in breast cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-Pd2-03 |
0.461 |
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| 2017 |
Park J, Jung K, Sirupangi T, Vithayathil S, Jin F, Putluri V, Piyarathna D, Yotnda P, Bhat V, Sreekumar A, Lewis M, Coarfa C, Putluri N, Creighton C, Wong L, et al. Abstract P6-01-07: Mitochondria-nuclear communication regulates epithelial-mesenchymal transition and metastasis in triple negative breast cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P6-01-07 |
0.371 |
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| 2017 |
Reddy J, Atkinson R, Larson R, Burks J, Smith D, Debeb B, Ruffell B, Creighton C, Reuben J, Krishnamurthy S, Symmans W, Brewster A, Laere SV. Abstract P4-03-14: Stem cell and macrophage markers are enriched in normal tissue adjacent to inflammatory breast cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P4-03-14 |
0.359 |
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| 2017 |
Amin S, Awadalla P, Biankin A, Boutros P, Brazma A, Brooks AN, Calabrese C, Chang D, Chateigner A, Chen K, Chong Z, Craft B, Creighton C, Demircioğlu D, Fonseca N, et al. Abstract SY10-02: Pan-cancer study of recurrent and heterogeneous RNA aberrations and association with whole-genome variants Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Sy10-02 |
0.329 |
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| 2017 |
Lei JT, Shao J, Zhang J, Iglesia M, Chan DW, Matsunuma R, He X, Singh P, Kosaka Y, Crowder R, Haricharan S, Kavuri S, Hoog J, Phommaly C, Goncalves R, ... ... Creighton CJ, et al. Abstract 1033: Estrogen receptor gene fusions drive endocrine therapy resistance in estrogen receptor positive breast cancer Cancer Research. 77: 1033-1033. DOI: 10.1158/1538-7445.Am2017-1033 |
0.433 |
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| 2017 |
Danussi C, Bose P, Parthasarathy P, Silberman P, Arnam JSV, Vitucci M, Tang O, Heguy A, Chan T, Sulman E, Lang F, Creighton CJ, Deneen B, Miller CR, Picketts D, et al. Gene-24. Atrx Deficiency In Glioma Cells Of Origin Promotes Disease-Defining Phenotypes By Way Of Global Epigenomic Remodeling Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.398 |
0.334 |
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| 2016 |
Zeng H, Ortiz A, Shen PF, Cheng CJ, Lee YC, Yu G, Lin SC, Creighton CJ, Yu-Lee LY, Lin SH. Angiomotin regulates prostate cancer cell proliferation by signaling through the Hippo-YAP pathway. Oncotarget. PMID 28052036 DOI: 10.18632/Oncotarget.14358 |
0.458 |
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| 2016 |
Tan X, Banerjee P, Guo HF, Ireland S, Pankova D, Ahn YH, Nikolaidis IM, Liu X, Zhao Y, Xue Y, Burns AR, Roybal J, Gibbons DL, Zal T, Creighton CJ, et al. Epithelial-to-mesenchymal transition drives a pro-metastatic Golgi compaction process through scaffolding protein PAQR11. The Journal of Clinical Investigation. PMID 27869652 DOI: 10.1172/Jci88736 |
0.377 |
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| 2016 |
Karatas OF, Suer I, Yuceturk B, Yilmaz M, Oz B, Guven G, Cansiz H, Creighton CJ, Ittmann M, Ozen M. Identification of microRNA profile specific to cancer stem-like cells directly isolated from human larynx cancer specimens. Bmc Cancer. 16: 853. PMID 27816053 DOI: 10.1186/S12885-016-2863-3 |
0.414 |
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| 2016 |
Fu X, Jeselsohn R, Pereira R, Hollingsworth EF, Creighton CJ, Li F, Shea M, Nardone A, De Angelis C, Heiser LM, Anur P, Wang N, Grasso CS, Spellman PT, Griffith OL, et al. FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 113: E6600-E6609. PMID 27791031 DOI: 10.1073/Pnas.1612835113 |
0.419 |
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| 2016 |
Chen F, Zhang Y, Parra E, Rodriguez J, Behrens C, Akbani R, Lu Y, Kurie JM, Gibbons DL, Mills GB, Wistuba II, Creighton CJ. Multiplatform-based molecular subtypes of non-small-cell lung cancer. Oncogene. PMID 27775076 DOI: 10.1038/Onc.2016.303 |
0.4 |
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| 2016 |
Peng DH, Ungewiss C, Tong P, Byers LA, Wang J, Canales JR, Villalobos PA, Uraoka N, Mino B, Behrens C, Wistuba II, Han RI, Wanna CA, Fahrenholtz M, Grande-Allen KJ, ... Creighton CJ, et al. ZEB1 induces LOXL2-mediated collagen stabilization and deposition in the extracellular matrix to drive lung cancer invasion and metastasis. Oncogene. PMID 27694892 DOI: 10.1038/Onc.2016.358 |
0.462 |
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| 2016 |
Treekitkarnmongkol W, Katayama H, Kai K, Sasai K, Jones JC, Wang J, Shen L, Sahin AA, Gagea Iurascu M, Ueno NT, Creighton CJ, Sen S. Aurora Kinase-A Overexpression in Mouse Mammary Epithelium Induces Mammary Adenocarcinomas Harboring Genetic Alterations Shared with Human Breast Cancer. Carcinogenesis. PMID 27624071 DOI: 10.1093/Carcin/Bgw097 |
0.493 |
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| 2016 |
Zhang B, Kwon OJ, Henry G, Malewska A, Wei X, Zhang L, Brinkley W, Zhang Y, Castro PD, Titus M, Chen R, Sayeeduddin M, Raj GV, Mauck R, Roehrborn C, ... Creighton CJ, et al. Non-Cell-Autonomous Regulation of Prostate Epithelial Homeostasis by Androgen Receptor. Molecular Cell. PMID 27594448 DOI: 10.1016/J.Molcel.2016.07.025 |
0.314 |
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| 2016 |
Zhang L, Wang J, Wang Y, Zhang Y, Castro P, Shao L, Sreekumar A, Putluri N, Guha N, Deepak S, Padmanaban A, Creighton CJ, Ittmann M. MNX1 is oncogenically upregulated in African-American prostate cancer. Cancer Research. PMID 27578002 DOI: 10.1158/0008-5472.Can-16-0087 |
0.347 |
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| 2016 |
Malouf GG, Compérat E, Yao H, Mouawad R, Lindner V, Rioux-Leclercq N, Verkarre V, Leroy X, Dainese L, Classe M, Descotes JL, Barthelemy P, Yacoub M, Rouprêt M, Bernhard JC, ... Creighton CJ, et al. Unique Transcriptomic Profile of Collecting Duct Carcinomas Relative to Upper Tract Urothelial Carcinomas and other Kidney Carcinomas. Scientific Reports. 6: 30988. PMID 27484008 DOI: 10.1038/Srep30988 |
0.356 |
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| 2016 |
Verstovsek S, Manshouri T, Pilling D, Bueso-Ramos CE, Newberry KJ, Prijic S, Knez L, Bozinovic K, Harris DM, Spaeth EL, Post SM, Multani AS, Rampal RK, Ahn J, Levine RL, ... Creighton CJ, et al. Role of neoplastic monocyte-derived fibrocytes in primary myelofibrosis. The Journal of Experimental Medicine. PMID 27481130 DOI: 10.1084/Jem.20160283 |
0.308 |
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| 2016 |
Zhang T, Guo L, Creighton CJ, Lu Q, Gibbons DL, Yi ES, Deng B, Molina JR, Sun Z, Yang P, Yang Y. A genetic cell context-dependent role for ZEB1 in lung cancer. Nature Communications. 7: 12231. PMID 27456471 DOI: 10.1038/Ncomms12231 |
0.377 |
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| 2016 |
Farach A, Ding Y, Lee M, Creighton C, Delk NA, Ittmann M, Miles B, Rowley D, Farach-Carson MC, Ayala GE. Neuronal trans-differentiation in prostate cancer cells. The Prostate. PMID 27403603 DOI: 10.1002/Pros.23221 |
0.385 |
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| 2016 |
Kwon OJ, Zhang L, Wang J, Su Q, Feng Q, Zhang XH, Mani SA, Paulter R, Creighton CJ, Ittmann MM, Xin L. Notch promotes tumor metastasis in a prostate-specific Pten-null mouse model. The Journal of Clinical Investigation. PMID 27294523 DOI: 10.1172/Jci84637 |
0.417 |
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| 2016 |
Lin SC, Kao CY, Lee HJ, Creighton CJ, Ittmann MM, Tsai SJ, Tsai SY, Tsai MJ. Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer. Nature Communications. 7: 11418. PMID 27108958 DOI: 10.1038/Ncomms11418 |
0.371 |
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| 2016 |
Vasquez YM, Wu SP, Anderson ML, Hawkins SM, Creighton CJ, Ray M, Tsai SY, Tsai MJ, Lydon JP, DeMayo FJ. Endometrial Expression of Steroidogenic Factor 1 Promotes Cystic Glandular Morphogenesis. Molecular Endocrinology (Baltimore, Md.). me20151215. PMID 27018534 DOI: 10.1210/Me.2015-1215 |
0.356 |
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| 2016 |
Malorni L, Giuliano M, Migliaccio I, Wang T, Creighton CJ, Lupien M, Fu X, Hilsenbeck SG, Healy N, De Angelis C, Mazumdar A, Trivedi MV, Massarweh S, Gutierrez C, De Placido S, et al. Blockade of AP-1 Potentiates Endocrine Therapy and Overcomes Resistance. Molecular Cancer Research : McR. PMID 26965145 DOI: 10.1158/1541-7786.Mcr-15-0423 |
0.384 |
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| 2016 |
Chen F, Zhang Y, Şenbabaoğlu Y, Ciriello G, Yang L, Reznik E, Shuch B, Micevic G, De Velasco G, Shinbrot E, Noble MS, Lu Y, Covington KR, Xi L, Drummond JA, ... ... Creighton CJ, et al. Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma. Cell Reports. PMID 26947078 DOI: 10.1016/J.Celrep.2016.02.024 |
0.366 |
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| 2016 |
Park JH, Vithayathil S, Kumar S, Sung PL, Dobrolecki LE, Putluri V, Bhat VB, Bhowmik SK, Gupta V, Arora K, Wu D, Tsouko E, Zhang Y, Maity S, Donti TR, ... ... Creighton CJ, et al. Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer. Cell Reports. PMID 26923594 DOI: 10.1016/J.Celrep.2016.02.004 |
0.397 |
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| 2016 |
Roca FJ, Loomans HA, Wittman AT, Creighton CJ, Hawkins SM. Ten-Eleven Translocation Genes are Downregulated in Endometriosis. Current Molecular Medicine. 16: 288-98. PMID 26917261 DOI: 10.2174/1566524016666160225153844 |
0.322 |
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| 2016 |
Nikolai BC, Lanz RB, York B, Dasgupta S, Mitsiades N, Creighton CJ, Tsimelzon A, Hilsenbeck SG, Lonard DM, Smith CL, O'Malley BW. HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes. Cancer Research. 76: 1463-75. PMID 26833126 DOI: 10.1158/0008-5472.Can-15-2383 |
0.448 |
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| 2016 |
Tsang YH, Dogruluk T, Tedeschi PM, Wardwell-Ozgo J, Lu H, Espitia M, Nair N, Minelli R, Chong Z, Chen F, Chang QE, Dennison JB, Dogruluk A, Li M, Ying H, ... ... Creighton CJ, et al. Functional annotation of rare gene aberration drivers of pancreatic cancer. Nature Communications. 7: 10500. PMID 26806015 DOI: 10.1038/Ncomms10500 |
0.463 |
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| 2016 |
Gingras MC, Covington KR, Chang DK, Donehower LA, Gill AJ, Ittmann MM, Creighton CJ, Johns AL, Shinbrot E, Dewal N, Fisher WE, Pilarsky C, Grützmann R, Overman MJ, et al. Ampullary Cancers Harbor the Tumor Suppressor Gene ELF3 and Exhibit Frequent WNT Dysregulation. Cell Reports. PMID 26804919 DOI: 10.1016/J.Celrep.2015.12.005 |
0.39 |
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| 2016 |
Hakimi AA, Reznik E, Lee CH, Creighton CJ, Brannon AR, Luna A, Aksoy BA, Liu EM, Shen R, Lee W, Chen Y, Stirdivant SM, Russo P, Chen YB, Tickoo SK, et al. An Integrated Metabolic Atlas of Clear Cell Renal Cell Carcinoma. Cancer Cell. 29: 104-116. PMID 26766592 DOI: 10.1016/J.Ccell.2015.12.004 |
0.323 |
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| 2016 |
Ungewiss C, Rizvi ZH, Roybal JD, Peng DH, Gold KA, Shin DH, Creighton CJ, Gibbons DL. The microRNA-200/Zeb1 axis regulates ECM-dependent β1-integrin/FAK signaling, cancer cell invasion and metastasis through CRKL. Scientific Reports. 6: 18652. PMID 26728244 DOI: 10.1038/Srep18652 |
0.444 |
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| 2016 |
Lerner SP, Kim J, Kwiatkowski DJ, Getz G, Weinstein JN, Cherniack A, Guo G, Akbani R, Hoadley KA, Kim WY, Robertson G, Mungall AJ, Hinoue T, Laird PW, Al-Ahmadie H, ... ... Creighton CJ, et al. Comprehensive characterization of 412 muscle invasive urothelial carcinomas: Final analysis of The Cancer Genome Atlas (TCGA) project. Journal of Clinical Oncology. 34: 405-405. DOI: 10.1200/Jco.2016.34.2_Suppl.405 |
0.385 |
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| 2016 |
Malouf GG, Comperat E, Yao H, Mouawad R, Lindner V, Rioux-Leclercq N, Verkarre V, Leroy X, Dainese L, Classe M, Descotes J, Barthelemy P, Yacoub M, Roupret M, Bernhard J, ... Creighton CJ, et al. Transcriptomic profiling of collecting duct carcinoma to reveal metabolic and immune aberrations. Journal of Clinical Oncology. 34: 4572-4572. DOI: 10.1200/Jco.2016.34.15_Suppl.4572 |
0.344 |
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| 2016 |
Kwon O, Zhang L, Jianghua W, Creighton C, Ittmann M, Xin L. Abstract A36: Notch signaling promotes tumor metastasis in the Pten null mouse model for prostate cancer Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-A36 |
0.444 |
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| 2016 |
Kundu ST, Grzeskowiak C, Creighton CJ, Scott KL, Gibbons DL. Abstract B25: A novel in vivo gain-of-function screen for metastasis drivers in non-small cell lung cancers Cancer Research. 76. DOI: 10.1158/1538-7445.Tummet15-B25 |
0.464 |
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| 2016 |
Peng DH, Tong P, Byers LA, Wang J, Creighton CJ, Gibbons DL. Abstract A27: Zeb1 induces LOXL2-mediated collagen stabilization and deposition in the extracellular matrix to drive lung cancer invasion and metastasis Cancer Research. 76. DOI: 10.1158/1538-7445.Tummet15-A27 |
0.461 |
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| 2016 |
Zheng Z, Bu W, Tian L, Fan C, Gao X, Zhang X, Yu C, Wang H, Liao Y, Li Y, Lewis M, Edwards D, Zwaka T, Hilsenbeck S, Medina D, ... ... Creighton C, et al. Abstract P2-06-11: Wild type N-Ras, overexpressed in basal-like breast cancer, promotes tumor formation by inducing IL8 secretion via JAK2 activation Cancer Research. 75: 2139-2139. DOI: 10.1158/1538-7445.Sabcs15-P2-06-11 |
0.393 |
|
| 2016 |
Casadei L, Creighton C, Batte K, Chelouche-Lev D, Croce CM, Pollock RE. Abstract 966: Circulating exosomal miRNAs as potential biomarker in liposarcoma Cancer Research. 76: 966-966. DOI: 10.1158/1538-7445.Am2016-966 |
0.319 |
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| 2016 |
Kundu S, Grzeskowiak C, Creighton CJ, Scott KL, Gibbons DL. Abstract 688: Identifying TMEM106B as a novel metastasis driver in non-small cell lung cancers through anin vivogain-of-function screen Cancer Research. 76: 688-688. DOI: 10.1158/1538-7445.Am2016-688 |
0.46 |
|
| 2016 |
Roarty K, Pfefferle AD, Creighton CJ, Perou CM, Rosen JM. Abstract 3306: Wnt pathway dynamics in breast cancer progression Cancer Research. 76: 3306-3306. DOI: 10.1158/1538-7445.Am2016-3306 |
0.468 |
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| 2016 |
Braggio D, Shang H, Lee Y, Al-Sannaa GA, Creighton CJ, Bolshakov S, Lazar AJ, Lev D, Pollock RE. Abstract 2286: Targeting the notch pathway: A potential therapeutic approach for desmoid tumors Cancer Research. 76: 2286-2286. DOI: 10.1158/1538-7445.Am2016-2286 |
0.441 |
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| 2016 |
Park JH, Vithayathil S, Wu D, Putluri V, Sung P, Tsouko E, Bhat VB, Coarfa C, Frigo DE, Lewis MT, Sreekumar A, Yotnda P, Creighton CJ, Putluri N, Wong LC, et al. Abstract 217: Mitochondrial reprogramming regulated cancer pathway in triple negative breast cancer Cancer Research. 76: 217-217. DOI: 10.1158/1538-7445.Am2016-217 |
0.42 |
|
| 2016 |
Weinstein JN, Lerner SP, Kwiatkowski DJ, Getz G, Kim J, Al-ahmadie HA, Cherniack AD, Guo G, Akbani R, Hoadley KA, Kim WY, Robertson G, Mungall AJ, Hinoue T, Laird PW, ... ... Creighton CJ, et al. Abstract 128: Comprehensive molecular characterization of 412 muscle-invasive urothelial bladder carcinomas: final analysis of The Cancer Genome Atlas (TCGA) project Cancer Research. 76: 128-128. DOI: 10.1158/1538-7445.Am2016-128 |
0.447 |
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| 2015 |
Lerner SP, Weinstein J, Kwiatkowski D, Kim J, Robertson G, Hoadley KA, Akbani R, Creighton C. The Cancer Genome Atlas Project on Muscle-invasive Bladder Cancer. European Urology Focus. 1: 94-95. PMID 28723366 DOI: 10.1016/J.Euf.2014.11.002 |
0.356 |
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| 2015 |
Monsivais D, Clementi C, Peng J, Titus MM, Barrish JP, Creighton CJ, Lydon JP, DeMayo FJ, Matzuk MM. Uterine ALK3 is essential during the window of implantation. Proceedings of the National Academy of Sciences of the United States of America. PMID 26721398 DOI: 10.1073/Pnas.1523758113 |
0.316 |
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| 2015 |
Duz MB, Karatas OF, Guzel E, Turgut NF, Yilmaz M, Creighton CJ, Ozen M. Identification of miR-139-5p as a saliva biomarker for tongue squamous cell carcinoma: a pilot study. Cellular Oncology (Dordrecht). PMID 26650483 DOI: 10.1007/S13402-015-0259-Z |
0.351 |
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| 2015 |
Pankoval D, Chen Y, Terajima M, Schliekelman MJ, Baird BN, Fahrenholtz M, Sun L, Gill BJ, Vadakkan TJ, Kim MP, Ahn YH, Roybal JD, Liu X, Parra Cuentas ER, Rodriguez J, ... ... Creighton CJ, et al. Cancer-associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma. Molecular Cancer Research : McR. PMID 26631572 DOI: 10.1158/1541-7786.Mcr-15-0307 |
0.397 |
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| 2015 |
Dogruluk T, Tsang YH, Espitia M, Chen F, Chen T, Chong Z, Appadurai V, Dogruluk A, Eterovic AK, Bonnen PE, Creighton CJ, Chen K, Mills GB, Scott KL. Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations. Cancer Research. PMID 26627007 DOI: 10.1158/0008-5472.Can-15-1654 |
0.386 |
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| 2015 |
Linehan WM, Spellman PT, Ricketts CJ, Creighton CJ, Fei SS, Davis C, Wheeler DA, Murray BA, Schmidt L, Vocke CD, Peto M, Al Mamun AA, Shinbrot E, Sethi A, Brooks S, et al. Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. The New England Journal of Medicine. PMID 26536169 DOI: 10.1056/Nejmoa1505917 |
0.314 |
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| 2015 |
Karatas OF, Suer I, Yuceturk B, Yilmaz M, Hajiyev Y, Creighton CJ, Ittmann M, Ozen M. The role of miR-145 in stem cell characteristics of human laryngeal squamous cell carcinoma Hep-2 cells. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. PMID 26490990 DOI: 10.1007/S13277-015-4219-Z |
0.37 |
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| 2015 |
Bill KL, Garnett J, Meaux I, Ma XY, Bolshakov S, Creighton CJ, Barriere C, Dubusche L, Lazar A, Prudner BC, Casadei L, Braggio DA, Lopez G, Zewdu A, Bid HK, et al. SAR405838: A novel and potent inhibitor of the MDM2:p53 axis for the treatment of dedifferentiated liposarcoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26475335 DOI: 10.1158/1078-0432.Ccr-15-1522 |
0.351 |
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| 2015 |
Kim J, Akbani R, Creighton CJ, Lerner SP, Weinstein JN, Getz G, Kwiatkowski DJ. Invasive Bladder Cancer: Genomic Insights and Therapeutic Promise. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 4514-24. PMID 26473186 DOI: 10.1158/1078-0432.Ccr-14-1215 |
0.444 |
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| 2015 |
Lopez G, Song Y, Lam R, Ruder D, Creighton CJ, Bid HK, Bill KL, Bolshakov S, Zhang X, Lev D, Pollock RE. HDAC Inhibition for the Treatment of Epithelioid Sarcoma: Novel Cross Talk Between Epigenetic Components. Molecular Cancer Research : McR. PMID 26396249 DOI: 10.1158/1541-7786.Mcr-15-0295 |
0.398 |
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| 2015 |
Shang H, Braggio D, Lee YJ, Al Sannaa GA, Creighton CJ, Bolshakov S, Lazar AJ, Lev D, Pollock RE. Targeting the Notch pathway: A potential therapeutic approach for desmoid tumors. Cancer. PMID 26349011 DOI: 10.1002/Cncr.29564 |
0.342 |
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| 2015 |
Fullerton PT, Creighton CJ, Matzuk MM. Insights Into SMAD4 Loss in Pancreatic Cancer From Inducible Restoration of TGF-β Signaling. Molecular Endocrinology (Baltimore, Md.). 29: 1440-53. PMID 26284758 DOI: 10.1210/Me.2015-1102 |
0.364 |
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| 2015 |
Creighton CJ, Huang S. Reverse phase protein arrays in signaling pathways: a data integration perspective. Drug Design, Development and Therapy. 9: 3519-27. PMID 26185419 DOI: 10.2147/Dddt.S38375 |
0.375 |
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| 2015 |
Zheng ZY, Tian L, Bu W, Fan C, Gao X, Wang H, Liao YH, Li Y, Lewis MT, Edwards D, Zwaka TP, Hilsenbeck SG, Medina D, Perou CM, Creighton CJ, et al. Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation. Cell Reports. PMID 26166574 DOI: 10.1016/J.Celrep.2015.06.044 |
0.367 |
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| 2015 |
Koparir A, Karatas OF, Yuceturk B, Yuksel B, Bayrak AO, Gerdan OF, Sagiroglu MS, Gezdirici A, Kirimtay K, Selcuk E, Karabay A, Creighton CJ, Yuksel A, Ozen M. Novel POC1A mutation in primordial dwarfism reveals new insights for centriole biogenesis. Human Molecular Genetics. 24: 5378-87. PMID 26162852 DOI: 10.1093/Hmg/Ddv261 |
0.328 |
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| 2015 |
Feng S, Wang J, Zhang Y, Creighton CJ, Ittmann M. FGF23 promotes prostate cancer progression. Oncotarget. PMID 26019137 DOI: 10.18632/Oncotarget.4174 |
0.396 |
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| 2015 |
Ozen M, Karatas OF, Gulluoglu S, Bayrak OF, Sevli S, Guzel E, Ekici ID, Caskurlu T, Solak M, Creighton CJ, Ittmann M. Overexpression of miR-145-5p inhibits proliferation of prostate cancer cells and reduces SOX2 expression. Cancer Investigation. 33: 251-8. PMID 25951106 DOI: 10.3109/07357907.2015.1025407 |
0.344 |
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| 2015 |
Rathmell KW, Chen F, Creighton CJ. Genomics of chromophobe renal cell carcinoma: implications from a rare tumor for pan-cancer studies. Oncoscience. 2: 81-90. PMID 25859550 DOI: 10.18632/oncoscience.130 |
0.335 |
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| 2015 |
Yu B, Swatkoski S, Holly A, Lee LC, Giroux V, Lee CS, Hsu D, Smith JL, Yuen G, Yue J, Ann DK, Simpson RM, Creighton CJ, Figg WD, Gucek M, et al. Oncogenesis driven by the Ras/Raf pathway requires the SUMO E2 ligase Ubc9. Proceedings of the National Academy of Sciences of the United States of America. 112: E1724-33. PMID 25805818 DOI: 10.1073/Pnas.1415569112 |
0.413 |
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| 2015 |
Kundu ST, Byers LA, Peng DH, Roybal JD, Diao L, Wang J, Tong P, Creighton CJ, Gibbons DL. The miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers. Oncogene. PMID 25798833 DOI: 10.1038/Onc.2015.71 |
0.398 |
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| 2015 |
Farrugia MK, Sharma SB, Lin CC, McLaughlin SL, Vanderbilt DB, Ammer AG, Salkeni MA, Stoilov P, Agazie YM, Creighton CJ, Ruppert JM. Regulation of anti-apoptotic signaling by Kruppel-like factors 4 and 5 mediates lapatinib resistance in breast cancer. Cell Death & Disease. 6: e1699. PMID 25789974 DOI: 10.1038/cddis.2015.65 |
0.369 |
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| 2015 |
Liu J, Cho SN, Akkanti B, Jin N, Mao J, Long W, Chen T, Zhang Y, Tang X, Wistub II, Creighton CJ, Kheradmand F, DeMayo FJ. ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis. Cell Reports. PMID 25753424 DOI: 10.1016/J.Celrep.2015.02.014 |
0.461 |
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| 2015 |
Zhang L, Shao L, Creighton CJ, Zhang Y, Xin L, Ittmann M, Wang J. Function of phosphorylation of NF-kB p65 ser536 in prostate cancer oncogenesis. Oncotarget. 6: 6281-94. PMID 25749044 DOI: 10.18632/Oncotarget.3366 |
0.356 |
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| 2015 |
Mishra DK, Creighton CJ, Zhang Y, Chen F, Thrall MJ, Kim MP. Ex vivo four-dimensional lung cancer model mimics metastasis. The Annals of Thoracic Surgery. 99: 1149-56. PMID 25701100 DOI: 10.1016/J.Athoracsur.2014.08.085 |
0.359 |
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| 2015 |
Chen Y, Terajima M, Yang Y, Sun L, Ahn YH, Pankova D, Puperi DS, Watanabe T, Kim MP, Blackmon SH, Rodriguez J, Liu H, Behrens C, Wistuba II, Minelli R, ... ... Creighton CJ, et al. Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma. The Journal of Clinical Investigation. 125: 1147-62. PMID 25664850 DOI: 10.1172/Jci74725 |
0.388 |
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| 2015 |
Roarty K, Shore AN, Creighton CJ, Rosen JM. Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium. The Journal of Cell Biology. 208: 351-66. PMID 25624393 DOI: 10.1083/Jcb.201408058 |
0.351 |
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| 2015 |
Zhao S, Kurenbekova L, Gao Y, Roos A, Creighton CJ, Rao P, Hicks J, Man TK, Lau C, Brown AM, Jones SN, Lazar AJ, Ingram D, Lev D, Donehower LA, et al. NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma. Oncogene. PMID 25579177 DOI: 10.1038/Onc.2014.429 |
0.437 |
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| 2015 |
Giuliano M, Herrera S, Christiny P, Shaw C, Creighton CJ, Mitchell T, Bhat R, Zhang X, Mao S, Dobrolecki LE, Al-rawi A, Chen F, Veneziani BM, Zhang XH, Hilsenbeck SG, et al. Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis. Breast Cancer Research : Bcr. 17: 3. PMID 25572662 DOI: 10.1186/S13058-014-0508-5 |
0.43 |
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| 2015 |
Hadsell DL, Hadsell LA, Olea W, Rijnkels M, Creighton CJ, Smyth I, Short KM, Cox LL, Cox TC. In-silico QTL mapping of postpubertal mammary ductal development in the mouse uncovers potential human breast cancer risk loci. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 26: 57-79. PMID 25552398 DOI: 10.1007/S00335-014-9551-X |
0.356 |
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| 2015 |
Addison JB, Koontz C, Fugett JH, Creighton CJ, Chen D, Farrugia MK, Padon RR, Voronkova MA, McLaughlin SL, Livengood RH, Lin CC, Ruppert JM, Pugacheva EN, Ivanov AV. KAP1 promotes proliferation and metastatic progression of breast cancer cells. Cancer Research. 75: 344-55. PMID 25421577 DOI: 10.1158/0008-5472.Can-14-1561 |
0.476 |
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| 2015 |
Quintás-Cardama A, Zhang N, Qiu YH, Post S, Creighton CJ, Cortes J, Coombes KR, Kornblau SM. Loss of TRIM62 expression is an independent adverse prognostic factor in acute myeloid leukemia. Clinical Lymphoma, Myeloma & Leukemia. 15: 115-127.e15. PMID 25248926 DOI: 10.1016/J.Clml.2014.07.011 |
0.348 |
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| 2015 |
Zhao D, Pan C, Sun J, Gilbert C, Drews-Elger K, Azzam DJ, Picon-Ruiz M, Kim M, Ullmer W, El-Ashry D, Creighton CJ, Slingerland JM. VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2. Oncogene. 34: 3107-19. PMID 25151964 DOI: 10.1038/Onc.2014.257 |
0.403 |
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| 2015 |
Guzel E, Karatas OF, Semercioz A, Ekici S, Aykan S, Yentur S, Creighton CJ, Ittmann M, Ozen M. Identification of microRNAs differentially expressed in prostatic secretions of patients with prostate cancer. International Journal of Cancer. Journal International Du Cancer. 136: 875-9. PMID 24976077 DOI: 10.1002/Ijc.29054 |
0.328 |
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| 2015 |
Bharadwaj U, Eckols TK, Kolosov M, Kasembeli MM, Adam A, Torres D, Zhang X, Dobrolecki LE, Wei W, Lewis MT, Dave B, Chang JC, Landis MD, Creighton CJ, Mancini MA, et al. Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer. Oncogene. 34: 1341-53. PMID 24681959 DOI: 10.1038/Onc.2014.72 |
0.458 |
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| 2015 |
Albiges L, Murray B, Brooks A, Cherniack A, Berger A, Creighton CJ, Ricketts C, Bottaro DP, Srinivasan R, Schmidt LS, Meyerson M, Spellman P, Linehan WM, Choueiri TK. Distinct MET alterations to induce a common phenotype and to define a MET-driven subset of papillary RCC: Results from the Cancer Genome Atlas (TCGA) Kidney Renal Papillary (KIRP) Working Group. Journal of Clinical Oncology. 33: 4521-4521. DOI: 10.1200/Jco.2015.33.15_Suppl.4521 |
0.369 |
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| 2015 |
Fu X, Jeselsohn R, Hollingsworth EF, Lopez-Terrada D, Creighton CJ, Nardone A, Shea M, Heiser LM, Anur P, Wang N, Grasso C, Spellman P, Gutierrez C, Rimawi MF, Hilsenbeck SG, et al. Abstract PD6-2: FoxA1 gene amplification in ER+ breast cancer mediates endocrine resistance by increasing IL-8 Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-Pd6-2 |
0.411 |
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| 2015 |
Westbrook TF, Nair A, Sun T, Karlin KL, Kessler J, Migliaccio I, Nguyen DX, Bernardi RJ, Renwick A, Creighton CJ, Dephoure N, Gygi SP, Shaw CA, Gibbs R, Wheeler D, et al. Abstract P6-11-01: A broad spectrum therapeutic strategy for TNBC revealed by a new pathway that coordinates oncogenic RTKs Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P6-11-01 |
0.458 |
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| 2015 |
Giuliano M, Herrera S, Christiny P, Shaw C, Creighton CJ, Mitchell T, Bhat R, Zhang X, Mao S, Dobrolecki L, Al-rawi A, Chen F, Veneziani BM, Zhang XH, Hilsenbeck SG, et al. Abstract P4-01-06: Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P4-01-06 |
0.443 |
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| 2015 |
Qin L, Hahn MB, Fu X, Shea MJ, Giuliano M, Nanda S, Xu X, Hu H, Jung SY, Heiser LM, Wang N, Gray JW, Hilsenbeck SG, Creighton C, Shaw CA, et al. Abstract P3-05-13: Overexpression of insulin receptor substrate 4 can mediate acquired resistance to lapatinib-containing regimens in HER2+ breast cancer cells Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P3-05-13 |
0.396 |
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| 2015 |
Park JH, Kumar S, Vithayathil S, Arora K, Putluri N, Tsouko E, Donti TR, Frigo DE, Creighton CJ, Lewis MT, Sreekumar A, Wong L, Kaipparettu BA. Abstract P1-07-06: Activation of oncogenic pathways by mitochondrial reprogramming in triple negative breast cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P1-07-06 |
0.474 |
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| 2015 |
Midorikawa Y, Yamamoto S, Tatsuno K, Ueda H, Tsuji S, Nagae G, Sonoda K, Shibata T, Covington KR, Creighton CJ, Sugitani M, Wheeler DA, Takayama T, Aburatani H. Abstract 958: Early hepatocellular carcinoma as another entity from classical hepatocellular carcinoma by integrated genomic analysis Cancer Research. 75: 958-958. DOI: 10.1158/1538-7445.Am2015-958 |
0.303 |
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| 2015 |
Park JH, Vithayathil SA, Putluri N, Tsouko E, Donti TR, Frigo DE, Creighton CJ, Lewis MT, Sreekumar A, Wong L, Kaipparettu BA. Abstract 3055: Regulation of mitochondria-nuclear crosstalk in triple negative breast cancer Cancer Research. 75: 3055-3055. DOI: 10.1158/1538-7445.Am2015-3055 |
0.477 |
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| 2015 |
Weinstein JN, Kim J, Creighton CJ, Akbani R, Hoadley KA, Kim WY, Morgan MB, Hinoue T, Cherniack A, Su X, Mungall AJ, Ryan MC, Bajorin DF, Rosenberg JE, Czerniak B, et al. Abstract 2969: Progress in The Cancer Genome Atlas bladder cancer project Cancer Research. 75: 2969-2969. DOI: 10.1158/1538-7445.Am2015-2969 |
0.365 |
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| 2015 |
Liu J, Cho S, Zhang Y, Creighton CJ, DeMayo FJ. Abstract 2308: The role of LKB1 in development of lung squamous cell carcinoma in mice Cancer Research. 75: 2308-2308. DOI: 10.1158/1538-7445.Am2015-2308 |
0.38 |
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| 2015 |
Zheng Z, Bu W, Tian L, Fan C, Gao X, Yu C, Jun L, Zhang X, Liao Y, Li Y, Lewis MT, Edwards D, Hilsenbeck SG, Medina D, Zwaka TP, ... ... Creighton CJ, et al. Abstract 2139: Wild type N-Ras, overexpressed in basal-like breast cancer, promotes tumor formation by inducing IL8 secretion via JAK2 activation Molecular and Cellular Biology. DOI: 10.1158/1538-7445.Am2015-2139 |
0.373 |
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| 2015 |
Lu H, Pantazi A, Dogruluk T, Dogruluk A, Creighton C, Mills GB, Kucherlapati R, Scott KL. Abstract 1099: High-throughput engineering and functional annotation of cancer fusion genes Cancer Research. 75: 1099-1099. DOI: 10.1158/1538-7445.Am2015-1099 |
0.345 |
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| 2015 |
Qi Y, Kai K, Creighton CJ, Eckhardt B, Saya H, Tripathy D, Ueno NT. Abstract 1078: TGF-β and TNF-α activate gene transcription programs associated with poor breast cancer prognosis Cancer Research. 75: 1078-1078. DOI: 10.1158/1538-7445.Am2015-1078 |
0.43 |
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| 2014 |
Totoki Y, Tatsuno K, Covington KR, Ueda H, Creighton CJ, Kato M, Tsuji S, Donehower LA, Slagle BL, Nakamura H, Yamamoto S, Shinbrot E, Hama N, Lehmkuhl M, Hosoda F, et al. Trans-ancestry mutational landscape of hepatocellular carcinoma genomes. Nature Genetics. 46: 1267-73. PMID 25362482 DOI: 10.1038/Ng.3126 |
0.339 |
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| 2014 |
Yang F, Chen Y, Shen T, Guo D, Dakhova O, Ittmann MM, Creighton CJ, Zhang Y, Dang TD, Rowley DR. Stromal TGF-β signaling induces AR activation in prostate cancer. Oncotarget. 5: 10854-69. PMID 25333263 DOI: 10.18632/Oncotarget.2536 |
0.344 |
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| 2014 |
Qin J, Lee HJ, Wu SP, Lin SC, Lanz RB, Creighton CJ, DeMayo FJ, Tsai SY, Tsai MJ. Androgen deprivation-induced NCoA2 promotes metastatic and castration-resistant prostate cancer. The Journal of Clinical Investigation. 124: 5013-26. PMID 25295534 DOI: 10.1172/Jci76412 |
0.406 |
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| 2014 |
Yu Z, Kim J, He L, Creighton CJ, Gunaratne PH, Hawkins SM, Matzuk MM. Functional analysis of miR-34c as a putative tumor suppressor in high-grade serous ovarian cancer. Biology of Reproduction. 91: 113. PMID 25273528 DOI: 10.1095/Biolreprod.114.121988 |
0.402 |
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| 2014 |
Fu X, Creighton CJ, Biswal NC, Kumar V, Shea M, Herrera S, Contreras A, Gutierrez C, Wang T, Nanda S, Giuliano M, Morrison G, Nardone A, Karlin KL, Westbrook TF, et al. Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase. Breast Cancer Research : Bcr. 16: 430. PMID 25212826 DOI: 10.1186/S13058-014-0430-X |
0.381 |
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| 2014 |
Davis CF, Ricketts CJ, Wang M, Yang L, Cherniack AD, Shen H, Buhay C, Kang H, Kim SC, Fahey CC, Hacker KE, Bhanot G, Gordenin DA, Chu A, Gunaratne PH, ... ... Creighton CJ, et al. The somatic genomic landscape of chromophobe renal cell carcinoma. Cancer Cell. 26: 319-30. PMID 25155756 DOI: 10.1016/J.Ccr.2014.07.014 |
0.389 |
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| 2014 |
Kwon OJ, Valdez JM, Zhang L, Zhang B, Wei X, Su Q, Ittmann MM, Creighton CJ, Xin L. Increased Notch signalling inhibits anoikis and stimulates proliferation of prostate luminal epithelial cells. Nature Communications. 5: 4416. PMID 25048699 DOI: 10.1038/Ncomms5416 |
0.367 |
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| 2014 |
Putluri N, Maity S, Kommagani R, Kommangani R, Creighton CJ, Putluri V, Chen F, Nanda S, Bhowmik SK, Terunuma A, Dorsey T, Nardone A, Fu X, Shaw C, Sarkar TR, et al. Pathway-centric integrative analysis identifies RRM2 as a prognostic marker in breast cancer associated with poor survival and tamoxifen resistance. Neoplasia (New York, N.Y.). 16: 390-402. PMID 25016594 DOI: 10.1016/J.Neo.2014.05.007 |
0.452 |
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| 2014 |
Karatas OF, Guzel E, Suer I, Ekici ID, Caskurlu T, Creighton CJ, Ittmann M, Ozen M. miR-1 and miR-133b are differentially expressed in patients with recurrent prostate cancer. Plos One. 9: e98675. PMID 24967583 DOI: 10.1371/Journal.Pone.0098675 |
0.323 |
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| 2014 |
Large MJ, Wetendorf M, Lanz RB, Hartig SM, Creighton CJ, Mancini MA, Kovanci E, Lee KF, Threadgill DW, Lydon JP, Jeong JW, DeMayo FJ. The epidermal growth factor receptor critically regulates endometrial function during early pregnancy. Plos Genetics. 10: e1004451. PMID 24945252 DOI: 10.1371/Journal.Pgen.1004451 |
0.364 |
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| 2014 |
Feng Q, Zhang Z, Shea MJ, Creighton CJ, Coarfa C, Hilsenbeck SG, Lanz R, He B, Wang L, Fu X, Nardone A, Song Y, Bradner J, Mitsiades N, Mitsiades CS, et al. An epigenomic approach to therapy for tamoxifen-resistant breast cancer. Cell Research. 24: 809-19. PMID 24874954 DOI: 10.1038/Cr.2014.71 |
0.431 |
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| 2014 |
Yang Y, Ahn YH, Chen Y, Tan X, Guo L, Gibbons DL, Ungewiss C, Peng DH, Liu X, Lin SH, Thilaganathan N, Wistuba II, Rodriguez-Canales J, McLendon G, Creighton CJ, et al. ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism. The Journal of Clinical Investigation. 124: 2696-708. PMID 24762440 DOI: 10.1172/Jci72171 |
0.427 |
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| 2014 |
Kommagani R, Szwarc MM, Kovanci E, Creighton CJ, O'Malley BW, Demayo FJ, Lydon JP. A murine uterine transcriptome, responsive to steroid receptor coactivator-2, reveals transcription factor 23 as essential for decidualization of human endometrial stromal cells. Biology of Reproduction. 90: 75. PMID 24571987 DOI: 10.1095/Biolreprod.114.117531 |
0.373 |
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| 2014 |
Liu S, Lai L, Zuo Q, Dai F, Wu L, Wang Y, Zhou Q, Liu J, Liu J, Li L, Lin Q, Creighton CJ, Costello MG, Huang S, Jia C, et al. PKA turnover by the REGγ-proteasome modulates FoxO1 cellular activity and VEGF-induced angiogenesis. Journal of Molecular and Cellular Cardiology. 72: 28-38. PMID 24560667 DOI: 10.1016/J.Yjmcc.2014.02.007 |
0.318 |
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| 2014 |
Weinstein JN, Akbani R, Broom BM, Wang W, Verhaak RGW, McConkey D, Lerner S, Morgan M, Creighton CJ, Smith C, Cherniack AD, Kim J, Pedamallu CS, Noble MS, Al-Ahmadie HA, et al. Comprehensive molecular characterization of urothelial bladder carcinoma Nature. 507: 315-322. PMID 24476821 DOI: 10.1038/Nature12965 |
0.424 |
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| 2014 |
Parikh N, Hilsenbeck S, Creighton CJ, Dayaram T, Shuck R, Shinbrot E, Xi L, Gibbs RA, Wheeler DA, Donehower LA. Effects of TP53 mutational status on gene expression patterns across 10 human cancer types. The Journal of Pathology. 232: 522-33. PMID 24374933 DOI: 10.1002/Path.4321 |
0.433 |
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| 2014 |
Geldres C, Savoldo B, Hoyos V, Caruana I, Zhang M, Yvon E, Del Vecchio M, Creighton CJ, Ittmann M, Ferrone S, Dotti G. T lymphocytes redirected against the chondroitin sulfate proteoglycan-4 control the growth of multiple solid tumors both in vitro and in vivo. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 962-71. PMID 24334762 DOI: 10.1158/1078-0432.Ccr-13-2218 |
0.36 |
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| 2014 |
Carstens JL, Shahi P, Van Tsang S, Smith B, Creighton CJ, Zhang Y, Seamans A, Seethammagari M, Vedula I, Levitt JM, Ittmann MM, Rowley DR, Spencer DM. FGFR1-WNT-TGF-β signaling in prostate cancer mouse models recapitulates human reactive stroma. Cancer Research. 74: 609-20. PMID 24305876 DOI: 10.1158/0008-5472.Can-13-1093 |
0.367 |
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| 2014 |
Zhang P, Garnett J, Creighton CJ, Al Sannaa GA, Igram DR, Lazar A, Liu X, Liu C, Pollock RE. EZH2-miR-30d-KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesis. The Journal of Pathology. 232: 308-18. PMID 24132643 DOI: 10.1002/Path.4294 |
0.358 |
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| 2014 |
Fan Y, Ge N, Wang X, Sun W, Mao R, Bu W, Creighton CJ, Zheng P, Vasudevan S, An L, Yang J, Zhao YJ, Zhang H, Li XN, Rao PH, et al. Amplification and over-expression of MAP3K3 gene in human breast cancer promotes formation and survival of breast cancer cells. The Journal of Pathology. 232: 75-86. PMID 24122835 DOI: 10.1002/Path.4283 |
0.437 |
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| 2014 |
Mishra DK, Creighton CJ, Zhang Y, Gibbons DL, Kurie JM, Kim MP. Gene expression profile of A549 cells from tissue of 4D model predicts poor prognosis in lung cancer patients. International Journal of Cancer. Journal International Du Cancer. 134: 789-98. PMID 23934967 DOI: 10.1002/Ijc.28428 |
0.389 |
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| 2014 |
Zhang B, Chen H, Zhang L, Dakhova O, Zhang Y, Lewis MT, Creighton CJ, Ittmann MM, Xin L. A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis. Oncogene. 33: 3099-108. PMID 23851498 DOI: 10.1038/Onc.2013.281 |
0.475 |
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| 2014 |
Wardwell-Ozgo J, Dogruluk T, Gifford A, Zhang Y, Heffernan TP, van Doorn R, Creighton CJ, Chin L, Scott KL. HOXA1 drives melanoma tumor growth and metastasis and elicits an invasion gene expression signature that prognosticates clinical outcome. Oncogene. 33: 1017-26. PMID 23435427 DOI: 10.1038/Onc.2013.30 |
0.356 |
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| 2014 |
Weinstein JN, Kim J, Creighton CJ, Akbani R, Hoadley KA, Kim WY, Morgan MB, Hinoue T, Rosenberg JE, Bajorin DF, Hansel DE, Al-Ahmadie H, Gordenin D, Stuart JM, Robertson G, et al. Comprehensive molecular profiling of urothelial bladder cancer at the DNA, RNA, and protein levels: A TCGA project. Journal of Clinical Oncology. 32: 4509-4509. DOI: 10.1200/Jco.2014.32.15_Suppl.4509 |
0.42 |
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| 2014 |
Yu B, Swatkoski S, Holly A, Lee LC, Giroux V, Lee C, Carver J, Creighton C, Ann DK, Figg WD, Gucek M, Luo J. Abstract B29: A critical role of the SUMO pathway in KRAS-driven oncogenesis Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-B29 |
0.392 |
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| 2014 |
Addison J, Koontz C, McLaughlin S, Livengood R, Pugacheva E, Chen D, Creighton C, Ivanov AV. Abstract LB-2: TRIM28 is overexpressed in breast cancer and regulates the expression of multiple cancer-associated genes Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-2 |
0.494 |
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| 2014 |
Weinstein JN, Kim J, Creighton CJ, Akbani R, Hoadley KA, Kim WY, Morgan MB, Hinoue T, Cherniack A, Su X, Mungall AJ, Ryan MC, Rosenberg JE, Bajorin DF, Czerniak B, et al. Abstract 987: Comprehensive characterization of urothelial bladder cancer: a TCGA Project update Cancer Research. 74: 987-987. DOI: 10.1158/1538-7445.Am2014-987 |
0.46 |
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| 2014 |
Anderson ML, Kim GE, Mach CM, Creighton CJ, Lev D. Abstract 5242: miR-10b functions as a novel tumor suppressor in uterine leiomyosarcoma by promoting overexpression of SDC1 Cancer Research. 74: 5242-5242. DOI: 10.1158/1538-7445.Am2014-5242 |
0.362 |
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| 2014 |
Park J, Arora K, Vithayathil SA, Donti TR, Creighton C, Lewis MT, Sreekumar A, Wong L, Kaipparettu BA. Abstract 4327: Mitochondrial reprogramming in triple negative breast cancer progression Cancer Research. 74: 4327-4327. DOI: 10.1158/1538-7445.Am2014-4327 |
0.453 |
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| 2014 |
Covington KR, Donehower LA, Creighton C, Slagle BL, Goss JA, Cotton RT, Gingras M, Shinbrot E, Guiteau JJ, Nguyen TN, Harring TR, Muzny DM, Walker K, Doddapaneni H, Gibbs RA, et al. Abstract 2211: Viral subtypes in hepatocellular carcinoma are associated with different mechanisms of WNT/CTNNB1 alteration Cancer Research. 74: 2211-2211. DOI: 10.1158/1538-7445.Am2014-2211 |
0.303 |
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| 2014 |
Kim M, Mishra D, Thrall M, Creighton C, Gibbons D, Kurie J, Kim M. A549 and H1299 Cells Form Metastatic Lesions in the Ex Vivo 4D Lung Cancer Model Journal of Surgical Research. 186: 557-558. DOI: 10.1016/J.Jss.2013.11.469 |
0.314 |
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| 2013 |
Creighton CJ. Widespread molecular patterns associated with drug sensitivity in breast cancer cell lines, with implications for human tumors. Plos One. 8: e71158. PMID 24386073 DOI: 10.1371/Journal.Pone.0071158 |
0.425 |
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| 2013 |
Clementi C, Tripurani SK, Large MJ, Edson MA, Creighton CJ, Hawkins SM, Kovanci E, Kaartinen V, Lydon JP, Pangas SA, DeMayo FJ, Matzuk MM. Activin-like kinase 2 functions in peri-implantation uterine signaling in mice and humans. Plos Genetics. 9: e1003863. PMID 24244176 DOI: 10.1371/Journal.Pgen.1003863 |
0.337 |
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| 2013 |
Kommagani R, Szwarc MM, Kovanci E, Gibbons WE, Putluri N, Maity S, Creighton CJ, Sreekumar A, DeMayo FJ, Lydon JP, O'Malley BW. Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization. Plos Genetics. 9: e1003900. PMID 24204309 DOI: 10.1371/Journal.Pgen.1003900 |
0.364 |
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| 2013 |
Li X, Large MJ, Creighton CJ, Lanz RB, Jeong JW, Young SL, Lessey BA, Palomino WA, Tsai SY, Demayo FJ. COUP-TFII regulates human endometrial stromal genes involved in inflammation. Molecular Endocrinology (Baltimore, Md.). 27: 2041-54. PMID 24176914 DOI: 10.1210/Me.2013-1191 |
0.384 |
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| 2013 |
Atkinson RL, Yang WT, Rosen DG, Landis MD, Wong H, Lewis MT, Creighton CJ, Sexton KR, Hilsenbeck SG, Sahin AA, Brewster AM, Woodward WA, Chang JC. Cancer stem cell markers are enriched in normal tissue adjacent to triple negative breast cancer and inversely correlated with DNA repair deficiency. Breast Cancer Research : Bcr. 15: R77. PMID 24008095 DOI: 10.1186/Bcr3471 |
0.409 |
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| 2013 |
Creighton CJ, Gibbons DL, Kurie JM. The role of epithelial-mesenchymal transition programming in invasion and metastasis: a clinical perspective. Cancer Management and Research. 5: 187-95. PMID 23986650 DOI: 10.2147/Cmar.S35171 |
0.501 |
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| 2013 |
Peng S, Creighton CJ, Zhang Y, Sen B, Mazumdar T, Myers JN, Lai SY, Woolfson A, Lorenzi MV, Bell D, Williams MD, Johnson FM. Tumor grafts derived from patients with head and neck squamous carcinoma authentically maintain the molecular and histologic characteristics of human cancers. Journal of Translational Medicine. 11: 198. PMID 23981300 DOI: 10.1186/1479-5876-11-198 |
0.359 |
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| 2013 |
Abazeed ME, Adams DJ, Hurov KE, Tamayo P, Creighton CJ, Sonkin D, Giacomelli AO, Du C, Fries DF, Wong KK, Mesirov JP, Loeffler JS, Schreiber SL, Hammerman PS, Meyerson M. Integrative radiogenomic profiling of squamous cell lung cancer. Cancer Research. 73: 6289-98. PMID 23980093 DOI: 10.1158/0008-5472.Can-13-1616 |
0.38 |
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| 2013 |
Lain AR, Creighton CJ, Conneely OM. Research resource: progesterone receptor targetome underlying mammary gland branching morphogenesis. Molecular Endocrinology (Baltimore, Md.). 27: 1743-61. PMID 23979845 DOI: 10.1210/Me.2013-1144 |
0.374 |
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| 2013 |
Bayrak OF, Gulluoglu S, Aydemir E, Ture U, Acar H, Atalay B, Demir Z, Sevli S, Creighton CJ, Ittmann M, Sahin F, Ozen M. MicroRNA expression profiling reveals the potential function of microRNA-31 in chordomas. Journal of Neuro-Oncology. 115: 143-51. PMID 23912551 DOI: 10.1007/S11060-013-1211-6 |
0.317 |
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| 2013 |
Kaipparettu BA, Ma Y, Park JH, Lee TL, Zhang Y, Yotnda P, Creighton CJ, Chan WY, Wong LJ. Crosstalk from non-cancerous mitochondria can inhibit tumor properties of metastatic cells by suppressing oncogenic pathways. Plos One. 8: e61747. PMID 23671572 DOI: 10.1371/Journal.Pone.0061747 |
0.415 |
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| 2013 |
Mach CM, Kim J, Soibam B, Creighton CJ, Hawkins SM, Zighelboim I, Goodfellow P, Gunaratne PH, Odunsi K, Salem PA, Anderson ML. Novel MicroRNAs regulating proliferation and apoptosis in uterine papillary serous carcinomas. Cancer Letters. 335: 314-22. PMID 23454583 DOI: 10.1016/J.Canlet.2013.02.043 |
0.338 |
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| 2013 |
Feng S, Dakhova O, Creighton CJ, Ittmann M. Endocrine fibroblast growth factor FGF19 promotes prostate cancer progression. Cancer Research. 73: 2551-62. PMID 23440425 DOI: 10.1158/0008-5472.Can-12-4108 |
0.392 |
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| 2013 |
Mo W, Chen J, Patel A, Zhang L, Chau V, Li Y, Cho W, Lim K, Xu J, Lazar AJ, Creighton CJ, Bolshakov S, McKay RM, Lev D, Le LQ, et al. CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors. Cell. 152: 1077-90. PMID 23434321 DOI: 10.1016/J.Cell.2013.01.053 |
0.378 |
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| 2013 |
Wander SA, Zhao D, Besser AH, Hong F, Wei J, Ince TA, Milikowski C, Bishopric NH, Minn AJ, Creighton CJ, Slingerland JM. PI3K/mTOR inhibition can impair tumor invasion and metastasis in vivo despite a lack of antiproliferative action in vitro: implications for targeted therapy. Breast Cancer Research and Treatment. 138: 369-81. PMID 23430223 DOI: 10.1007/S10549-012-2389-6 |
0.443 |
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| 2013 |
Hoffman A, Ghadimi MP, Demicco EG, Creighton CJ, Torres K, Colombo C, Peng T, Lusby K, Ingram D, Hornick JL, Wang WL, Ravi V, Lazar AJ, Lev D, Pollock RE. Localized and metastatic myxoid/round cell liposarcoma: clinical and molecular observations. Cancer. 119: 1868-77. PMID 23401071 DOI: 10.1002/Cncr.27847 |
0.303 |
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| 2013 |
Lusby K, Savannah KB, Demicco EG, Zhang Y, Ghadimi MP, Young ED, Colombo C, Lam R, Dogan TE, Hornick JL, Lazar AJ, Hunt KK, Anderson ML, Creighton CJ, Lev D, et al. Uterine leiomyosarcoma management, outcome, and associated molecular biomarkers: a single institution's experience. Annals of Surgical Oncology. 20: 2364-72. PMID 23334251 DOI: 10.1245/S10434-012-2834-0 |
0.367 |
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| 2013 |
Verhaak RG, Tamayo P, Yang JY, Hubbard D, Zhang H, Creighton CJ, Fereday S, Lawrence M, Carter SL, Mermel CH, Kostic AD, Etemadmoghadam D, Saksena G, Cibulskis K, Duraisamy S, et al. Prognostically relevant gene signatures of high-grade serous ovarian carcinoma. The Journal of Clinical Investigation. 123: 517-25. PMID 23257362 DOI: 10.1172/Jci65833 |
0.37 |
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| 2013 |
Qin J, Wu SP, Creighton CJ, Dai F, Xie X, Cheng CM, Frolov A, Ayala G, Lin X, Feng XH, Ittmann MM, Tsai SJ, Tsai MJ, Tsai SY. COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis. Nature. 493: 236-40. PMID 23201680 DOI: 10.1038/Nature11674 |
0.374 |
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| 2013 |
Donehower LA, Creighton CJ, Schultz N, Shinbrot E, Chang K, Gunaratne PH, Muzny D, Sander C, Hamilton SR, Gibbs RA, Wheeler D. MLH1-silenced and non-silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes. The Journal of Pathology. 229: 99-110. PMID 22899370 DOI: 10.1002/Path.4087 |
0.325 |
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| 2013 |
Wardwell-Ozgo J, Dogruluk T, Gifford A, zhang Y, Doorn Rv, Creighton C, Scott K. Abstract 3881: HOXA1 drives melanoma tumor growth and metastasis and elicits an invasion gene expression signature that prognosticates clinical outcome. Cancer Research. 73: 3881-3881. DOI: 10.1158/1538-7445.Am2013-3881 |
0.357 |
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| 2013 |
Peng S, Creighton C, Zhang Y, Sen B, Mazumdar T, Myers J, Bell D, El-Naggar A, Williams M, Johnson F. Abstract 333: Molecular and histologic characterization a patient-derived heterotransplant mouse model of head and neck squamous carcinoma. Cancer Research. 73: 333-333. DOI: 10.1158/1538-7445.Am2013-333 |
0.427 |
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| 2013 |
Kumar S, Gupta V, Vithayathil S, Park J, Donti TR, Creighton CJ, Lewis MT, Sreekumar A, Wong L, Kaipparettu BA. Abstract 1696: Mitochondria-nuclear cross talk regulate cancer properties by activating oncogenic pathways. Cancer Research. 73: 1696-1696. DOI: 10.1158/1538-7445.Am2013-1696 |
0.422 |
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| 2013 |
Mishra DK, Creighton C, Zhang Y, Gibbons DL, Kurie JM, Kim MP. Abstract 1508: Gene expression analysis of perfusable nodules grown onex vivo3D model shows effects on extracellular matrix, cell signaling and immune response. Cancer Research. 73: 1508-1508. DOI: 10.1158/1538-7445.Am2013-1508 |
0.398 |
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| 2013 |
Chakravarti D, Su X, Cho M, Gi YJ, Benham A, Coarfa C, Venkatanarayan A, Alana J, Creighton C, Xiao w, Leung M, Vin H, Chan IL, Aquino A, Müller N, et al. Abstract 1119: Induced pluripotency in adult keratinocytes through downregulation of ΔNp63 or DGCR8. Cancer Research. 73: 1119-1119. DOI: 10.1158/1538-7445.Am2013-1119 |
0.372 |
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| 2013 |
Trivedi M, Bhat R, Yadav V, Yadav P, Al-Rawi A, Christiny P, Nanda S, Giuliano M, Creighton C, Osborne C, Narkar V, Schiff R. Abstract P6-04-05: GPR110 overexpression increases tumorigenic potential of HER2+ breast cancer cells Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P6-04-05 |
0.453 |
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| 2012 |
Creighton CJ. Using large-scale molecular data sets to improve breast cancer treatment. Breast Cancer Management. 1: 57-64. PMID 23869198 DOI: 10.2217/Bmt.12.14 |
0.415 |
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| 2012 |
Weng MT, Lee JH, Wei SC, Li Q, Shahamatdar S, Hsu D, Schetter AJ, Swatkoski S, Mannan P, Garfield S, Gucek M, Kim MK, Annunziata CM, Creighton CJ, Emanuele MJ, et al. Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 109: E3659-67. PMID 23236152 DOI: 10.1073/Pnas.1207673110 |
0.448 |
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| 2012 |
Valdez JM, Zhang L, Su Q, Dakhova O, Zhang Y, Shahi P, Spencer DM, Creighton CJ, Ittmann MM, Xin L. Notch and TGFβ form a reciprocal positive regulatory loop that suppresses murine prostate basal stem/progenitor cell activity. Cell Stem Cell. 11: 676-88. PMID 23122291 DOI: 10.1016/J.Stem.2012.07.003 |
0.334 |
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| 2012 |
Creighton CJ. Molecular classification and drug response prediction in cancer. Current Drug Targets. 13: 1488-94. PMID 22974392 DOI: 10.2174/138945012803530143 |
0.402 |
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| 2012 |
Creighton CJ. The molecular profile of luminal B breast cancer. Biologics : Targets & Therapy. 6: 289-97. PMID 22956860 DOI: 10.2147/Btt.S29923 |
0.456 |
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| 2012 |
Shore AN, Kabotyanski EB, Roarty K, Smith MA, Zhang Y, Creighton CJ, Dinger ME, Rosen JM. Pregnancy-induced noncoding RNA (PINC) associates with polycomb repressive complex 2 and regulates mammary epithelial differentiation. Plos Genetics. 8: e1002840. PMID 22911650 DOI: 10.1371/Journal.Pgen.1002840 |
0.341 |
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| 2012 |
Ahn YH, Gibbons DL, Chakravarti D, Creighton CJ, Rizvi ZH, Adams HP, Pertsemlidis A, Gregory PA, Wright JA, Goodall GJ, Flores ER, Kurie JM. ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression. The Journal of Clinical Investigation. 122: 3170-83. PMID 22850877 DOI: 10.1172/Jci63608 |
0.384 |
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| 2012 |
Brewer Savannah KJ, Demicco EG, Lusby K, Ghadimi MP, Belousov R, Young E, Zhang Y, Huang KL, Lazar AJ, Hunt KK, Pollock RE, Creighton CJ, Anderson ML, Lev D. Dual targeting of mTOR and aurora-A kinase for the treatment of uterine Leiomyosarcoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 4633-45. PMID 22821997 DOI: 10.1158/1078-0432.Ccr-12-0436 |
0.383 |
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| 2012 |
Muzny DM, Bainbridge MN, Chang K, Dinh HH, Drummond JA, Fowler G, Kovar CL, Lewis LR, Morgan MB, Newsham IF, Reid JG, Santibanez J, Shinbrot E, Trevino LR, Wu YQ, ... ... Creighton CJ, et al. Comprehensive molecular characterization of human colon and rectal cancer Nature. 487: 330-337. PMID 22810696 DOI: 10.1038/Nature11252 |
0.397 |
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| 2012 |
Hawkins SM, Andreu-Vieyra CV, Kim TH, Jeong JW, Hodgson MC, Chen R, Creighton CJ, Lydon JP, Gunaratne PH, DeMayo FJ, Matzuk MM. Dysregulation of uterine signaling pathways in progesterone receptor-Cre knockout of dicer. Molecular Endocrinology (Baltimore, Md.). 26: 1552-66. PMID 22798293 DOI: 10.1210/Me.2012-1042 |
0.345 |
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| 2012 |
Chen AC, Migliaccio I, Rimawi M, Lopez-Tarruella S, Creighton CJ, Massarweh S, Huang C, Wang YC, Batra SK, Gutierrez MC, Osborne CK, Schiff R. Upregulation of mucin4 in ER-positive/HER2-overexpressing breast cancer xenografts with acquired resistance to endocrine and HER2-targeted therapies. Breast Cancer Research and Treatment. 134: 583-93. PMID 22644656 DOI: 10.1007/S10549-012-2082-9 |
0.406 |
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| 2012 |
Xu J, Wan M, He Q, Bassett RL, Fu X, Chen AC, Shi F, Creighton CJ, Schiff R, Huo L, Liu D. SGK3 is associated with estrogen receptor expression in breast cancer. Breast Cancer Research and Treatment. 134: 531-41. PMID 22576469 DOI: 10.1007/S10549-012-2081-X |
0.449 |
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| 2012 |
Shan W, Akinfenwa PY, Savannah KB, Kolomeyevskaya N, Laucirica R, Thomas DG, Odunsi K, Creighton CJ, Lev DC, Anderson ML. A small-molecule inhibitor targeting the mitotic spindle checkpoint impairs the growth of uterine leiomyosarcoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3352-65. PMID 22535157 DOI: 10.1158/1078-0432.Ccr-11-3058 |
0.403 |
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| 2012 |
Creighton CJ, Hernandez-Herrera A, Jacobsen A, Levine DA, Mankoo P, Schultz N, Du Y, Zhang Y, Larsson E, Sheridan R, Xiao W, Spellman PT, Getz G, Wheeler DA, Perou CM, et al. Integrated analyses of microRNAs demonstrate their widespread influence on gene expression in high-grade serous ovarian carcinoma. Plos One. 7: e34546. PMID 22479643 DOI: 10.1371/Journal.Pone.0034546 |
0.352 |
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| 2012 |
Ghadimi MP, Young ED, Belousov R, Zhang Y, Lopez G, Lusby K, Kivlin C, Demicco EG, Creighton CJ, Lazar AJ, Pollock RE, Lev D. Survivin is a viable target for the treatment of malignant peripheral nerve sheath tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 2545-57. PMID 22407831 DOI: 10.1158/1078-0432.Ccr-11-2592 |
0.391 |
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| 2012 |
Kim J, Coffey DM, Creighton CJ, Yu Z, Hawkins SM, Matzuk MM. High-grade serous ovarian cancer arises from fallopian tube in a mouse model. Proceedings of the National Academy of Sciences of the United States of America. 109: 3921-6. PMID 22331912 DOI: 10.1073/Pnas.1117135109 |
0.429 |
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| 2012 |
Kessler JD, Kahle KT, Sun T, Meerbrey KL, Schlabach MR, Schmitt EM, Skinner SO, Xu Q, Li MZ, Hartman ZC, Rao M, Yu P, Dominguez-Vidana R, Liang AC, Solimini NL, ... ... Creighton CJ, et al. A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. Science (New York, N.Y.). 335: 348-53. PMID 22157079 DOI: 10.1126/Science.1212728 |
0.458 |
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| 2012 |
Creighton CJ, Sada YH, Zhang Y, Tsimelzon A, Wong H, Dave B, Landis MD, Bear HD, Rodriguez A, Chang JC. A gene transcription signature of obesity in breast cancer. Breast Cancer Research and Treatment. 132: 993-1000. PMID 21750966 DOI: 10.1007/S10549-011-1595-Y |
0.363 |
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| 2012 |
Casa AJ, Potter AS, Malik S, Lazard Z, Kuiatse I, Kim HT, Tsimelzon A, Creighton CJ, Hilsenbeck SG, Brown PH, Oesterreich S, Lee AV. Estrogen and insulin-like growth factor-I (IGF-I) independently down-regulate critical repressors of breast cancer growth. Breast Cancer Research and Treatment. 132: 61-73. PMID 21541704 DOI: 10.1007/S10549-011-1540-0 |
0.435 |
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| 2012 |
Shore AN, Kabotyanski EB, Roarty K, Smith MA, Zhang Y, Creighton CJ, Dinger ME, Rosen JM. Overexpression of mPINC inhibits differentiation of HC11 cells. Plos Genetics. DOI: 10.1371/Journal.Pgen.1002840.G005 |
0.323 |
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| 2012 |
Kim J, Coffey DM, Creighton CJ, Yu Z, Hawkins SM, Matzuk MM. Abstract 4878: The fallopian tube is the origin of high-grade serous ovarian carcinomas in a mouse model Cancer Research. 72: 4878-4878. DOI: 10.1158/1538-7445.Am2012-4878 |
0.436 |
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| 2012 |
Azzam DJ, Elger KD, Zhao D, Ranganathan P, Capobianco T, Minn AJ, Creighton C, Picon M, Sun J, Pan C, Wander SA, Ashry DE, Slingerland JM. Abstract 3478: CD44+CD24low+progenitors in ER negative breast cancer have higher Notch1 activation, self-renewal, and chemo resistance and generate CD44+CD24negcells and tumors that metastasize Cancer Research. 72: 3478-3478. DOI: 10.1158/1538-7445.Am2012-3478 |
0.34 |
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| 2012 |
Kessler JD, Kahle KT, Sun T, Meerbrey KL, Schlabach MR, Schmitt EM, Skinner SO, Xu Q, Li MZ, Hartman ZC, Rao M, Yu P, Dominguez-Vidana R, Liang AC, Solimini NL, ... ... Creighton C, et al. Abstract 3091: A sumoylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis Cancer Research. 72: 3091-3091. DOI: 10.1158/1538-7445.Am2012-3091 |
0.45 |
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| 2012 |
Fu X, Kumar V, Shea M, Biswal N, Nanda S, Chayanam S, Mitchell T, Hergenroeder G, Meerbrey K, Joshi A, Westbrook T, Mills G, Creighton C, Hilsenbeck S, Osborne C, et al. Abstract PD01-01: Overcoming endocrine therapy resistance related to PTEN loss by strategic combinations with mTOR, AKT, or MEK inhibitors Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-Pd01-01 |
0.383 |
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| 2012 |
Yadav P, Bhat R, Chayanam S, Christiny P, Nanda S, Hu H, Creighton C, Osborne C, Schiff R, Trivedi M. Abstract P4-06-02: Identification of novel G-protein coupled receptor targets in HER2-positive breast cancer. Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P4-06-02 |
0.397 |
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| 2012 |
Au JK, Florentin D, Ding Y, He D, Creighton CJ, Frolov A, Dakhova O, Zhang Y, Smith C, Kadmon D, Miles B, Ittmann M, Rowley D, Ayala G. 313 Influence Of The Neural Microenvironment In Prostate Cancer The Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.373 |
0.325 |
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| 2012 |
Ayala G, Florentin D, Au JK, Ding Y, He D, Creighton CJ, Frolov A, Dakhova O, Zhang Y, Smith C, Kadmon D, Miles B, Ittmann M, Rowley D. 1633 TARGETING THE NEURAL MICROENVIRONMENT IN PROSTATE CANCER: A NEOADJUVANT BOTOX CLINICAL TRIAL Journal of Urology. 187. DOI: 10.1016/J.Juro.2012.02.1450 |
0.322 |
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| 2011 |
Batts TD, Machado HL, Zhang Y, Creighton CJ, Li Y, Rosen JM. Stem cell antigen-1 (sca-1) regulates mammary tumor development and cell migration. Plos One. 6: e27841. PMID 22140470 DOI: 10.1371/Journal.Pone.0027841 |
0.428 |
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| 2011 |
Dong J, Huang S, Caikovski M, Ji S, McGrath A, Custorio MG, Creighton CJ, Maliakkal P, Bogoslovskaia E, Du Z, Zhang X, Lewis MT, Sablitzky F, Brisken C, Li Y. ID4 regulates mammary gland development by suppressing p38MAPK activity. Development (Cambridge, England). 138: 5247-56. PMID 22069192 DOI: 10.1242/Dev.069203 |
0.385 |
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| 2011 |
Schliekelman MJ, Gibbons DL, Faca VM, Creighton CJ, Rizvi ZH, Zhang Q, Wong CH, Wang H, Ungewiss C, Ahn YH, Shin DH, Kurie JM, Hanash SM. Targets of the tumor suppressor miR-200 in regulation of the epithelial-mesenchymal transition in cancer. Cancer Research. 71: 7670-82. PMID 21987723 DOI: 10.1158/0008-5472.Can-11-0964 |
0.407 |
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| 2011 |
Ahn YH, Yang Y, Gibbons DL, Creighton CJ, Yang F, Wistuba II, Lin W, Thilaganathan N, Alvarez CA, Roybal J, Goldsmith EJ, Tournier C, Kurie JM. Map2k4 functions as a tumor suppressor in lung adenocarcinoma and inhibits tumor cell invasion by decreasing peroxisome proliferator-activated receptor γ2 expression. Molecular and Cellular Biology. 31: 4270-85. PMID 21896780 DOI: 10.1128/Mcb.05562-11 |
0.431 |
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| 2011 |
Colombo C, Creighton CJ, Ghadimi MP, Bolshakov S, Warneke CL, Zhang Y, Lusby K, Zhu S, Lazar AJ, West RB, van de Rijn M, Lev D. Increased midkine expression correlates with desmoid tumour recurrence: a potential biomarker and therapeutic target. The Journal of Pathology. 225: 574-82. PMID 21826666 DOI: 10.1002/Path.2951 |
0.386 |
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| 2011 |
Putluri N, Shojaie A, Vasu VT, Nalluri S, Vareed SK, Putluri V, Vivekanandan-Giri A, Byun J, Pennathur S, Sana TR, Fischer SM, Palapattu GS, Creighton CJ, Michailidis G, Sreekumar A. Metabolomic profiling reveals a role for androgen in activating amino acid metabolism and methylation in prostate cancer cells. Plos One. 6: e21417. PMID 21789170 DOI: 10.1371/Journal.Pone.0021417 |
0.38 |
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| 2011 |
Yu W, Feng S, Dakhova O, Creighton CJ, Cai Y, Wang J, Li R, Frolov A, Ayala G, Ittmann M. FGFR-4 Arg³â¸â¸ enhances prostate cancer progression via extracellular signal-related kinase and serum response factor signaling. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4355-66. PMID 21622724 DOI: 10.1158/1078-0432.Ccr-10-2858 |
0.384 |
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| 2011 |
Helland Ã…, Anglesio MS, George J, Cowin PA, Johnstone CN, House CM, Sheppard KE, Etemadmoghadam D, Melnyk N, Rustgi AK, Phillips WA, Johnsen H, Holm R, Kristensen GB, Birrer MJ, ... ... Creighton CJ, et al. Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers. Plos One. 6: e18064. PMID 21533284 DOI: 10.1371/Journal.Pone.0018064 |
0.432 |
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| 2011 |
Bu W, Chen J, Morrison GD, Huang S, Creighton CJ, Huang J, Chamness GC, Hilsenbeck SG, Roop DR, Leavitt AD, Li Y. Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer Oncogene. 30: 4399-4409. PMID 21532625 DOI: 10.1038/Onc.2011.147 |
0.462 |
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| 2011 |
Vareed SK, Bhat VB, Thompson C, Vasu VT, Fermin D, Choi H, Creighton CJ, Gayatri S, Lan L, Putluri N, Thangjam GS, Kaur P, Shabahang M, Giri JG, Nesvizhskii AI, et al. Metabolites of purine nucleoside phosphorylase (NP) in serum have the potential to delineate pancreatic adenocarcinoma. Plos One. 6: e17177. PMID 21448452 DOI: 10.1371/Journal.Pone.0017177 |
0.33 |
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| 2011 |
Mullany LK, Fan HY, Liu Z, White LD, Marshall A, Gunaratne P, Anderson ML, Creighton CJ, Xin L, Deavers M, Wong KK, Richards JS. Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo. Oncogene. 30: 3522-36. PMID 21423204 DOI: 10.1038/Onc.2011.70 |
0.466 |
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| 2011 |
Yang Y, Ahn YH, Gibbons DL, Zang Y, Lin W, Thilaganathan N, Alvarez CA, Moreira DC, Creighton CJ, Gregory PA, Goodall GJ, Kurie JM. The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. The Journal of Clinical Investigation. 121: 1373-85. PMID 21403400 DOI: 10.1172/Jci42579 |
0.384 |
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| 2011 |
Sun T, Aceto N, Meerbrey KL, Kessler JD, Zhou C, Migliaccio I, Nguyen DX, Pavlova NN, Botero M, Huang J, Bernardi RJ, Schmitt E, Hu G, Li MZ, Dephoure N, ... ... Creighton CJ, et al. Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase. Cell. 144: 703-18. PMID 21376233 DOI: 10.1016/J.Cell.2011.02.003 |
0.432 |
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| 2011 |
Litzenburger BC, Creighton CJ, Tsimelzon A, Chan BT, Hilsenbeck SG, Wang T, Carboni JM, Gottardis MM, Huang F, Chang JC, Lewis MT, Rimawi MF, Lee AV. High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 2314-27. PMID 21177763 DOI: 10.1158/1078-0432.Ccr-10-1903 |
0.403 |
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| 2011 |
Roybal JD, Zang Y, Ahn YH, Yang Y, Gibbons DL, Baird BN, Alvarez C, Thilaganathan N, Liu DD, Saintigny P, Heymach JV, Creighton CJ, Kurie JM. miR-200 Inhibits lung adenocarcinoma cell invasion and metastasis by targeting Flt1/VEGFR1. Molecular Cancer Research : McR. 9: 25-35. PMID 21115742 DOI: 10.1158/1541-7786.Mcr-10-0497 |
0.403 |
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| 2011 |
Suo J, Snider SJ, Mills GB, Creighton CJ, Chen AC, Schiff R, Lloyd RE, Chang EC. Int6 regulates both proteasomal degradation and translation initiation and is critical for proper formation of acini by human mammary epithelium. Oncogene. 30: 724-36. PMID 20890303 DOI: 10.1038/Onc.2010.445 |
0.336 |
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| 2011 |
Quintás-Cardama A, Qiu YH, Post S, Zhang Y, Creighton C, Cortes JE, Kornblau SM. Proteomic Profiling of 112 Proteins in Chronic Myeloid Leukemia Patient Samples Using Reverse Phase Proteins Arrays (RPPA) Reveals Distinct Protein Expression Signatures Associated with Advanced Phase Disease and the CD34+ Compartment Blood. 118: 2503-2503. DOI: 10.1182/Blood.V118.21.2503.2503 |
0.325 |
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| 2011 |
Atkinson RL, Yang WT, Landis MD, Wong H, Creighton C, Hilsenbeck SG, Lewis MT, Woodward WA, Brewster A, Sahin AA, Chang JC. Abstract LB-106: Expression of stem cell biomarkers in benign breast tissue from patients with triple negative breast cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-106 |
0.424 |
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| 2011 |
Fu X, Nanda S, Gillihan RM, Shea M, Creighton CJ, Hilsenbeck SG, Lee AV, Schiff R, Osborne KC. Abstract 2290: Crosstalk between ER and PI3K signaling pathways in human luminal type breast cancer and its therapeutic implications Cancer Research. 71: 2290-2290. DOI: 10.1158/1538-7445.Am2011-2290 |
0.416 |
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| 2011 |
Creighton C. SR2-3: Integrative Genomic Analyses of Breast Cancer from The Cancer Genome Atlas (TCGA). Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-Sr2-3 |
0.477 |
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| 2011 |
Malorni L, Giuliano M, Migliaccio I, Wang T, Creighton C, Lupien M, Hilsenbeck S, Healy N, Mazumdar A, Trivedi M, Jeselsohn R, He H, Fu X, Gutierrez C, Brown M, et al. P4-01-18: AP-1 Blockade Potentiates the Anti-Tumor Effect of Endocrine Treatment and Reverts the Resistant Phenotype in Hormone Receptor-Positive Breast Cancer. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P4-01-18 |
0.389 |
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| 2011 |
Healy N, Creighton C, Fu X, Tsimelzon A, Hilsenbeck S, Miller N, Kerin M, Osborne C, Schiff R. P3-03-05: Identification of miRNAs and Their Associated Target Genes Involved in Endocrine Resistance in Breast Cancer. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P3-03-05 |
0.396 |
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| 2011 |
Mach C, Kim J, Creighton C, Gunaratne P, Anderson M. A unique microRNA locus at 19q13.41 sensitizes epithelial ovarian cancers to chemotherapy Gynecologic Oncology. 120. DOI: 10.1016/J.Ygyno.2010.12.016 |
0.35 |
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| 2010 |
Su X, Chakravarti D, Cho MS, Liu L, Gi YJ, Lin YL, Leung ML, El-Naggar A, Creighton CJ, Suraokar MB, Wistuba I, Flores ER. TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs. Nature. 467: 986-90. PMID 20962848 DOI: 10.1038/Nature09459 |
0.337 |
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| 2010 |
Feng S, Agoulnik IU, Truong A, Li Z, Creighton CJ, Kaftanovskaya EM, Pereira R, Han HD, Lopez-Berestein G, Klonisch T, Ittmann MM, Sood AK, Agoulnik AI. Suppression of relaxin receptor RXFP1 decreases prostate cancer growth and metastasis. Endocrine-Related Cancer. 17: 1021-33. PMID 20861284 DOI: 10.1677/Erc-10-0073 |
0.455 |
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| 2010 |
Creighton CJ, Fu X, Hennessy BT, Casa AJ, Zhang Y, Gonzalez-Angulo AM, Lluch A, Gray JW, Brown PH, Hilsenbeck SG, Osborne CK, Mills GB, Lee AV, Schiff R. Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer. Breast Cancer Research : Bcr. 12: R40. PMID 20569503 DOI: 10.1186/Bcr2594 |
0.391 |
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| 2010 |
Pond AC, Herschkowitz JI, Schwertfeger KL, Welm B, Zhang Y, York B, Cardiff RD, Hilsenbeck S, Perou CM, Creighton CJ, Lloyd RE, Rosen JM. Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer. Cancer Research. 70: 4868-79. PMID 20501844 DOI: 10.1158/0008-5472.Can-09-4404 |
0.445 |
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| 2010 |
Monaco ME, Creighton CJ, Lee P, Zou X, Topham MK, Stafforini DM. Expression of Long-chain Fatty Acyl-CoA Synthetase 4 in Breast and Prostate Cancers Is Associated with Sex Steroid Hormone Receptor Negativity. Translational Oncology. 3: 91-8. PMID 20360933 DOI: 10.1593/Tlo.09202 |
0.434 |
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| 2010 |
Creighton CJ, Chang JC, Rosen JM. Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer. Journal of Mammary Gland Biology and Neoplasia. 15: 253-60. PMID 20354771 DOI: 10.1007/S10911-010-9173-1 |
0.49 |
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| 2010 |
Creighton CJ, Fountain MD, Yu Z, Nagaraja AK, Zhu H, Khan M, Olokpa E, Zariff A, Gunaratne PH, Matzuk MM, Anderson ML. Molecular profiling uncovers a p53-associated role for microRNA-31 in inhibiting the proliferation of serous ovarian carcinomas and other cancers. Cancer Research. 70: 1906-15. PMID 20179198 DOI: 10.1158/0008-5472.Can-09-3875 |
0.434 |
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| 2010 |
Franco HL, Lee KY, Rubel CA, Creighton CJ, White LD, Broaddus RR, Lewis MT, Lydon JP, Jeong JW, DeMayo FJ. Constitutive activation of smoothened leads to female infertility and altered uterine differentiation in the mouse Biology of Reproduction. 82: 991-999. PMID 20130264 DOI: 10.1095/Biolreprod.109.081513 |
0.306 |
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| 2010 |
Nagaraja AK, Creighton CJ, Yu Z, Zhu H, Gunaratne PH, Reid JG, Olokpa E, Itamochi H, Ueno NT, Hawkins SM, Anderson ML, Matzuk MM. A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer. Molecular Endocrinology (Baltimore, Md.). 24: 447-63. PMID 20081105 DOI: 10.1210/Me.2009-0295 |
0.432 |
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| 2010 |
LaMarca HL, Visbal AP, Creighton CJ, Liu H, Zhang Y, Behbod F, Rosen JM. CCAAT/enhancer binding protein beta regulates stem cell activity and specifies luminal cell fate in the mammary gland. Stem Cells (Dayton, Ohio). 28: 535-44. PMID 20054865 DOI: 10.1002/Stem.297 |
0.379 |
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| 2010 |
Hammerich-Hille S, Kaipparettu BA, Tsimelzon A, Creighton CJ, Jiang S, Polo JM, Melnick A, Meyer R, Oesterreich S. SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells. The Journal of Biological Chemistry. 285: 3608-16. PMID 19901029 DOI: 10.1074/Jbc.M109.066431 |
0.4 |
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| 2010 |
Zhang L, Zhao W, Valdez JM, Creighton CJ, Xin L. Low-density taqman miRNA array reveals miRNAs differentially expressed in prostatic stem cells and luminal cells Prostate. 70: 297-304. PMID 19827049 DOI: 10.1002/Pros.21064 |
0.33 |
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| 2010 |
Pond AC, Herschkowitz JI, Hilsenbeck S, Creighton C, Lloyd RE, Rosen JM. Abstract 282: FGF receptor signaling accelerates Wnt-1 mammary tumorigenesis and enhances translation of Wnt/β-catenin target oncogenes Cancer Research. 70: 282-282. DOI: 10.1158/1538-7445.Am10-282 |
0.462 |
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| 2010 |
Gunaratne P, Ghosh R, Mach C, Creighton CJ, Levine DA, Hayes DN, Wheeler D, Matzuk MM, Anderson ML, Gibbs RA. Abstract 2029: Identification of novel tumor suppressor microRNAs implicated in epithelial ovarian cancer from the 19q13.41 non-coding RNA cluster Cancer Research. 70: 2029-2029. DOI: 10.1158/1538-7445.Am10-2029 |
0.401 |
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| 2010 |
Sun T, Meerbrey K, Kessler J, Botero M, Migliaccio I, Nguyen D, Pavlova N, Bernardi R, Schmitt E, Hilsenbeck S, Creighton C, Shaw C, Gibbs R, Wheeler D, Osborne C, et al. Abstract S6-10: Identification of a Novel Tumor Suppressor Network Reveals a Role for Proto-Oncogenic Receptor Tyrosine Kinases in Triple-Negative Breast Cancer Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-S6-10 |
0.458 |
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| 2010 |
Arias PA, Creighton CJ, Yu Z, Gunaratne PH, Anderson ML, Matzuk MM, Hawkins SM. MicroRNAs in Endometrioid Ovarian Cancer Target the Ephrin Receptor Signaling Pathway. Biology of Reproduction. 83: 692-692. DOI: 10.1093/Biolreprod/83.S1.692 |
0.374 |
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| 2010 |
Yu Z, Creighton C, Fountain MD, Nagaraja AK, Zhu H, Khan MF, Han DY, Olokpa E, Hawkins SM, Gunaratne P, Anderson ML, Matzuk MM. MiR-31 Is a Tumor Suppressor MicroRNA That Functions in Ovarian Cancer. Biology of Reproduction. 83: 35-35. DOI: 10.1093/Biolreprod/83.S1.35 |
0.368 |
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| 2009 |
Gibbons DL, Lin W, Creighton C, Zhang S, Lozano G, Kurie J. Use of a murine model of NSCLC to evaluate the role of the microRNA-200 family in regulating EMT and metastasis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 11006. PMID 27964037 DOI: 10.1200/Jco.2009.27.15_Suppl.11006 |
0.397 |
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| 2009 |
Chang CC, Zhou X, Taylor JJ, Huang WT, Ren X, Monzon F, Feng Y, Rao PH, Lu XY, Fabio F, Hilsenbeck S, Creighton CJ, Jaffe ES, Lau CC. Genomic profiling of plasmablastic lymphoma using array comparative genomic hybridization (aCGH): revealing significant overlapping genomic lesions with diffuse large B-cell lymphoma. Journal of Hematology & Oncology. 2: 47. PMID 19909553 DOI: 10.1186/1756-8722-2-47 |
0.302 |
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| 2009 |
Gibbons DL, Lin W, Creighton CJ, Rizvi ZH, Gregory PA, Goodall GJ, Thilaganathan N, Du L, Zhang Y, Pertsemlidis A, Kurie JM. Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression. Genes & Development. 23: 2140-51. PMID 19759262 DOI: 10.1101/Gad.1820209 |
0.422 |
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| 2009 |
Creighton CJ, Li X, Landis M, Dixon JM, Neumeister VM, Sjolund A, Rimm DL, Wong H, Rodriguez A, Herschkowitz JI, Fan C, Zhang X, He X, Pavlick A, Gutierrez MC, et al. Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proceedings of the National Academy of Sciences of the United States of America. 106: 13820-5. PMID 19666588 DOI: 10.1073/Pnas.0905718106 |
0.41 |
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| 2009 |
Dakhova O, Ozen M, Creighton CJ, Li R, Ayala G, Rowley D, Ittmann M. Global gene expression analysis of reactive stroma in prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 3979-89. PMID 19509179 DOI: 10.1158/1078-0432.Ccr-08-1899 |
0.428 |
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| 2009 |
Luo J, Emanuele MJ, Li D, Creighton CJ, Schlabach MR, Westbrook TF, Wong KK, Elledge SJ. A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene Cell. 137: 835-848. PMID 19490893 DOI: 10.1016/J.Cell.2009.05.006 |
0.369 |
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| 2009 |
Gibbons DL, Lin W, Creighton CJ, Zheng S, Berel D, Yang Y, Raso MG, Liu DD, Wistuba II, Lozano G, Kurie JM. Expression signatures of metastatic capacity in a genetic mouse model of lung adenocarcinoma. Plos One. 4: e5401. PMID 19404390 DOI: 10.1371/Journal.Pone.0005401 |
0.368 |
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| 2009 |
Choi K, Ahn YH, Gibbons DL, Tran HT, Creighton CJ, Girard L, Minna JD, Qin FX, Kurie JM. Distinct biological roles for the notch ligands Jagged-1 and Jagged-2. The Journal of Biological Chemistry. 284: 17766-74. PMID 19398556 DOI: 10.1074/Jbc.M109.003111 |
0.394 |
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| 2009 |
Creighton CJ, Reid JG, Gunaratne PH. Expression profiling of microRNAs by deep sequencing. Briefings in Bioinformatics. 10: 490-7. PMID 19332473 DOI: 10.1093/Bib/Bbp019 |
0.321 |
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| 2009 |
Castro P, Creighton CJ, Ozen M, Bcrel D, Mims MP, Ittmann M. Genomic profiling of prostate cancers from African American men 1 Neoplasia. 11: 305-312. PMID 19242612 DOI: 10.1593/Neo.81530 |
0.365 |
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| 2009 |
Creighton CJ, Kent Osborne C, Van De Vijver MJ, Foekens JA, Klijn JG, Horlings HM, Nuyten D, Wang Y, Zhang Y, Chamness GC, Hilsenbeck SG, Lee AV, Schiff R. Molecular profiles of progesterone receptor loss in human breast tumors Breast Cancer Research and Treatment. 114: 287-299. PMID 18425577 DOI: 10.1007/S10549-008-0017-2 |
0.405 |
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| 2009 |
Creighton C, Fu X, Hilsenbeck S, Osborne C, Hennessy B, Mills G, Lee A, Schiff R. Gene Expression Signatures of PI3K Signaling Are Associated with Low ER Levels and the Luminal B Subtype in Breast Cancer Cell Lines and Human Tumors, and in Patients Predicts Poor Outcome. Cancer Research. 69: 31-31. DOI: 10.1158/0008-5472.Sabcs-09-31 |
0.428 |
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| 2009 |
Litzenburger B, Tsimelzon A, Hilsenbeck S, Creighton C, Carboni J, Gottardis M, Wicha M, Chang J, Lewis M, Lee A. High IGF-IR Activity in Triple-Negative Breast Cancer Cell Lines Correlates with Sensitivity to IGF-IR Inhibitor BMS-754807 in This Subtype of Human Breast Cancer. Cancer Research. 69: 1132-1132. DOI: 10.1158/0008-5472.Sabcs-09-1132 |
0.439 |
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| 2009 |
Casa A, Malik S, Lazard Z, Kuiatse I, Tsimelzon A, Creighton C, Hilsenbeck S, Lee A, Oesterreich S. Estrogen and IGF-I Independently Down-Regulate Critical Repressors of Breast Cancer Growth. Cancer Research. 69: 1126-1126. DOI: 10.1158/0008-5472.Sabcs-09-1126 |
0.435 |
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| 2009 |
Yang Y, Ahn Y, Gibbons DL, Zang Y, Lin W, Thilaganthan N, Moreira DC, Creighton CJ, Goodall GJ, Kurie JM. Abstract A29: The Notch ligand Jagged2 promotes metastasis through a GATA3/miR‐200 regulatory loop Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-A29 |
0.416 |
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| 2009 |
Ayala GE, Ding Y, Creighton C, Rowley DR. Neuronal Mimicry As A Resistance Phenotype In Cancer Cells The Journal of Urology. 181: 211-211. DOI: 10.1016/S0022-5347(09)60607-8 |
0.34 |
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| 2008 |
Chang JC, Creighton C, Landis M, Lewis MT, Li X, Pavlick A, Rosen J, Perou CM, Rosen J. Gene signature of cancer stem cells in an intrinsic subgroup of breast cancers with mesenchymal properties. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 11009. PMID 27948335 DOI: 10.1200/Jco.2008.26.15_Suppl.11009 |
0.409 |
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| 2008 |
Creighton CJ, Nagaraja AK, Hanash SM, Matzuk MM, Gunaratne PH. A bioinformatics tool for linking gene expression profiling results with public databases of microRNA target predictions. Rna (New York, N.Y.). 14: 2290-6. PMID 18812437 DOI: 10.1261/Rna.1188208 |
0.349 |
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| 2008 |
Creighton CJ, Massarweh S, Huang S, Tsimelzon A, Hilsenbeck SG, Osborne CK, Shou J, Malorni L, Schiff R. Development of resistance to targeted therapies transforms the clinically associated molecular profile subtype of breast tumor xenografts. Cancer Research. 68: 7493-501. PMID 18794137 DOI: 10.1158/0008-5472.Can-08-1404 |
0.449 |
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| 2008 |
Zhong L, Roybal J, Chaerkady R, Zhang W, Choi K, Alvarez CA, Tran H, Creighton CJ, Yan S, Strieter RM, Pandey A, Kurie JM. Identification of secreted proteins that mediate cell-cell interactions in an in vitro model of the lung cancer microenvironment Cancer Research. 68: 7237-7245. PMID 18757440 DOI: 10.1158/0008-5472.Can-08-1529 |
0.4 |
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| 2008 |
Creighton CJ, Casa A, Lazard Z, Huang S, Tsimelzon A, Hilsenbeck SG, Osborne CK, Lee AV. Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 4078-85. PMID 18757322 DOI: 10.1200/Jco.2007.13.4429 |
0.451 |
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| 2008 |
Fernandez-Valdivia R, Mukherjee A, Creighton CJ, Buser AC, DeMayo FJ, Edwards DP, Lydon JP. Transcriptional response of the murine mammary gland to acute progesterone exposure. Endocrinology. 149: 6236-50. PMID 18687774 DOI: 10.1210/En.2008-0768 |
0.373 |
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| 2008 |
Gu P, Reid JG, Gao X, Shaw CA, Creighton C, Tran PL, Zhou X, Drabek RB, Steffen DL, Hoang DM, Weiss MK, Naghavi AO, El-daye J, Khan MF, Legge GB, et al. Novel microRNA candidates and miRNA-mRNA pairs in embryonic stem (ES) cells. Plos One. 3: e2548. PMID 18648548 DOI: 10.1371/Journal.Pone.0002548 |
0.305 |
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| 2008 |
Creighton CJ. Multiple oncogenic pathway signatures show coordinate expression patterns in human prostate tumors Plos One. 3. PMID 18350153 DOI: 10.1371/Journal.Pone.0001816 |
0.424 |
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| 2008 |
Iwanaga K, Yang Y, Raso MG, Ma L, Hanna AE, Thilaganathan N, Moghaddam S, Evans CM, Li H, Cai WW, Sato M, Minna JD, Wu H, Creighton CJ, Demayo FJ, et al. Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer. Cancer Research. 68: 1119-27. PMID 18281487 DOI: 10.1158/0008-5472.Can-07-3117 |
0.315 |
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| 2008 |
Massarweh S, Osborne CK, Creighton CJ, Qin L, Tsimelzon A, Huang S, Weiss H, Rimawi M, Schiff R. Tamoxifen resistance in breast tumors is driven by growth factor receptor signaling with repression of classic estrogen receptor genomic function. Cancer Research. 68: 826-33. PMID 18245484 DOI: 10.1158/0008-5472.Can-07-2707 |
0.389 |
|
| 2008 |
Ozen M, Creighton CJ, Ozdemir M, Ittmann M. Widespread deregulation of microRNA expression in human prostate cancer Oncogene. 27: 1788-1793. PMID 17891175 DOI: 10.1038/Sj.Onc.1210809 |
0.377 |
|
| 2008 |
Nagaraja AK, Creighton CJ, Reid JG, Gunaratne PH, Ma L, Anderson ML, Matzuk MM. MicroRNAs in Human Ovarian Cancer. Biology of Reproduction. 78: 200-200. DOI: 10.1093/Biolreprod/78.S1.200A |
0.369 |
|
| 2007 |
Choi K, Creighton CJ, Stivers D, Fujimoto N, Kurie JM. Transcriptional profiling of non-small cell lung cancer cells with activating EGFR somatic mutations Plos One. 2. PMID 18030354 DOI: 10.1371/Journal.Pone.0001226 |
0.357 |
|
| 2007 |
Yu J, Cao Q, Mehra R, Laxman B, Yu J, Tomlins SA, Creighton CJ, Dhanasekaran SM, Shen R, Chen G, Morris DS, Marquez VE, Shah RB, Ghosh D, Varambally S, et al. Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer. Cancer Cell. 12: 419-31. PMID 17996646 DOI: 10.1016/J.Ccr.2007.10.016 |
0.422 |
|
| 2007 |
Creighton CJ. A gene transcription signature associated with hormone independence in a subset of both breast and prostate cancers Bmc Genomics. 8. PMID 17598908 DOI: 10.1186/1471-2164-8-199 |
0.442 |
|
| 2007 |
Creighton CJ. A gene transcription signature of the Akt/mTOR pathway in clinical breast tumors Oncogene. 26: 4648-4655. PMID 17213801 DOI: 10.1038/Sj.Onc.1210245 |
0.45 |
|
| 2007 |
Rae JM, Creighton CJ, Meck JM, Haddad BR, Johnson MD. MDA-MB-435 cells are derived from M14 melanoma cells--a loss for breast cancer, but a boon for melanoma research. Breast Cancer Research and Treatment. 104: 13-9. PMID 17004106 DOI: 10.1007/S10549-006-9392-8 |
0.379 |
|
| 2007 |
Chang JC, Li X, Wong H, Creighton C, Hilsenbeck SG, Osborne CK, Rosen JM, Lewis MT. Therapeutic resistance and tumor-initiation: Molecular pathways involved in breast cancer stem cell self-renewal Journal of Clinical Oncology. 25: 528-528. DOI: 10.1200/Jco.2007.25.18_Suppl.528 |
0.396 |
|
| 2007 |
Makris A, Creighton C, Osborne KC, Hilsenbeck S, Harrison MK, Ostler PJ, Spears C, Brown P, Elledge R, Chang JC. Predictive gene expression patterns of response to adriamycin and cyclophosphamide (AC) in human breast cancers Journal of Clinical Oncology. 25: 527-527. DOI: 10.1200/Jco.2007.25.18_Suppl.527 |
0.38 |
|
| 2007 |
Tham Y, Creighton C, Gutierrez C, Osborne CK, Brown P, Chang JC. A gene expression signature of eventual brain metastases in patients with breast cancer Journal of Clinical Oncology. 25: 1019-1019. DOI: 10.1200/Jco.2007.25.18_Suppl.1019 |
0.389 |
|
| 2006 |
Creighton CJ, Rae JM. When will tumor gene expression profiling be incorporated into clinical breast cancer decision making? Breast Cancer Research : Bcr. 8: 302. PMID 16834787 DOI: 10.1186/Bcr1519 |
0.442 |
|
| 2006 |
Haas CS, Creighton CJ, Pi X, Maine I, Koch AE, Haines GK, Ling S, Chinnaiyan AM, Holoshitz J. Identification of genes modulated in rheumatoid arthritis using complementary DNA microarray analysis of lymphoblastoid B cell lines from disease-discordant monozygotic twins Arthritis and Rheumatism. 54: 2047-2060. PMID 16804865 DOI: 10.1002/Art.21953 |
0.308 |
|
| 2006 |
Creighton CJ, Cordero KE, Larios JM, Miller RS, Johnson MD, Chinnaiyan AM, Lippman ME, Rae JM. Genes regulated by estrogen in breast tumor cells in vitro are similarly regulated in vivo in tumor xenografts and human breast tumors. Genome Biology. 7: R28. PMID 16606439 DOI: 10.1186/Gb-2006-7-4-R28 |
0.451 |
|
| 2006 |
Creighton CJ, Hilger AM, Murthy S, Rae JM, Chinnaiyan AM, El-Ashry D. Activation of mitogen-activated protein kinase in estrogen receptor alpha-positive breast cancer cells in vitro induces an in vivo molecular phenotype of estrogen receptor alpha-negative human breast tumors. Cancer Research. 66: 3903-11. PMID 16585219 DOI: 10.1158/0008-5472.Can-05-4363 |
0.472 |
|
| 2006 |
Creighton C, Rae J, Chinnaiyan A, Lippman M. Improved prediction of disease-free survival in tamoxifen-treated patients using an expression signature of estrogen-regulated genes as compared to progesterone receptor Journal of Clinical Oncology. 24: 535-535. DOI: 10.1200/Jco.2006.24.18_Suppl.535 |
0.412 |
|
| 2005 |
Creighton CJ, Bromberg-White JL, Misek DE, Monsma DJ, Brichory F, Kuick R, Giordano TJ, Gao W, Omenn GS, Webb CP, Hanash SM. Analysis of tumor-host interactions by gene expression profiling of lung adenocarcinoma xenografts identifies genes involved in tumor formation. Molecular Cancer Research : McR. 3: 119-29. PMID 15798092 DOI: 10.1158/1541-7786.Mcr-04-0189 |
0.466 |
|
| 2005 |
Dhanasekaran SM, Dash A, Yu J, Maine IP, Laxman B, Tomlins SA, Creighton CJ, Menon A, Rubin MA, Chinnaiyan AM. Molecular profiling of human prostate tissues: insights into gene expression patterns of prostate development during puberty The Faseb Journal. 19: 243-245. PMID 15548588 DOI: 10.1096/Fj.04-2415Fje |
0.307 |
|
| 2003 |
Hanash S, Creighton C. Making sense of microarray data to classify cancer Pharmacogenomics Journal. 3: 308-311. PMID 14597962 DOI: 10.1038/Sj.Tpj.6500209 |
0.409 |
|
| 2003 |
Creighton C, Kuick R, Misek DE, Rickman DS, Brichory FM, Rouillard JM, Omenn GS, Hanash S. Profiling of pathway-specific changes in gene expression following growth of human cancer cell lines transplanted into mice. Genome Biology. 4: R46. PMID 12844362 DOI: 10.1186/Gb-2003-4-7-R46 |
0.476 |
|
| 2003 |
Creighton C, Hanash S, Beer D. Gene expression patterns define pathways correlated with loss of differentiation in lung adenocarcinomas. Febs Letters. 540: 167-170. PMID 12681502 DOI: 10.1016/S0014-5793(03)00259-X |
0.387 |
|
| 2003 |
Creighton C, Hanash S. Mining gene expression databases for association rules Bioinformatics. 19: 79-86. PMID 12499296 DOI: 10.1093/Bioinformatics/19.1.79 |
0.314 |
|
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