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Walid S. Kamoun, Ph.D. - Publications

Affiliations: 
2006 University of North Carolina, Charlotte, Charlotte, NC, United States 
Area:
Physiology Biology, Oncology
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46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kamoun WS, Kirpotin DB, Huang ZR, Tipparaju SK, Noble CO, Hayes ME, Luus L, Koshkaryev A, Kim J, Olivier K, Kornaga T, Oyama S, Askoxylakis V, Pien C, Kuesters G, et al. Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse models. Nature Biomedical Engineering. 3: 264-280. PMID 30952988 DOI: 10.1038/S41551-019-0385-4  0.305
2019 Dumont N, Merrigan S, Turpin J, Lavoie C, Papavasiliou V, Geretti E, Espelin C, Luus L, Kamoun W, Ghasemi O, Sahagian GG, Muller W, Hendriks B, Wickham TJ, Drummond DC. Nanoliposome targeting in breast Cancer is influenced by the tumor microenvironment. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 30654182 DOI: 10.1016/J.Nano.2018.12.010  0.331
2019 Koshkaryev A, Alkan O, Geng B, Luus L, Raue A, Kamoun W, Tipparaju S, Kirpotin D, Drummond D. Abstract 8: Targeting DNA-damage response pathway with a novel nano-liposomal ATR inhibitor in solid tumors Cancer Research. 79: 8-8. DOI: 10.1158/1538-7445.Sabcs18-8  0.332
2018 Ernstoff MS, Ma WW, Tsai FY, Munster PN, Zhang T, Kamoun W, Pipas JM, Chen S, Santillana S, Askoxylakis V. A phase 1 study evaluating the safety, pharmacology and preliminary activity of MM-310 in patients with solid tumors. Journal of Clinical Oncology. 36. DOI: 10.1200/Jco.2018.36.15_Suppl.Tps2604  0.315
2018 Kamoun W, Swindell E, Pien C, Luus L, Cain J, Kandela I, Huang R, Tipparaju S, Kirpotin D, Bshara W, Askoxylakis V, Morrison C, Drummond D. Abstract 5771: Targeting EphA2 in bladder cancer using a novel antibody-directed nanotherapeutic Cancer Research. 78: 5771-5771. DOI: 10.1158/1538-7445.Am2018-5771  0.357
2017 Kamoun WS, Sawyer AJ, Pien C, Koshkaryev A, Luus L, Merrigan S, Sun G, Kozin S, Huang ZR, Tipparaju SK, Kirpotin DB, Xu H, Askoxylakis V, Reynolds PC, Drummond DC. Abstract 3096: Mechanisms of synergy of carboplatin and an EphA2-targeted docetaxel antibody-directed nanotherapeutic Cancer Research. 77: 3096-3096. DOI: 10.1158/1538-7445.Am2017-3096  0.355
2016 Peterson TE, Kirkpatrick ND, Huang Y, Farrar CT, Marijt KA, Kloepper J, Datta M, Amoozgar Z, Seano G, Jung K, Kamoun WS, Vardam T, Snuderl M, Goveia J, Chatterjee S, et al. Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages. Proceedings of the National Academy of Sciences of the United States of America. PMID 27044097 DOI: 10.1073/Pnas.1525349113  0.39
2016 Amoozgar Z, Peterson TE, Kirkpatrick ND, Huang Y, Farrar CT, Marijt KA, Kloepper J, Datta M, Seano G, Jung K, Kamoun WS, Vardam T, Snuderl M, Goveia J, Chatterjee S, et al. Abstract LB-346: Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-346  0.394
2016 Kamoun WS, Luus L, Pien C, Kornaga T, Oyama S, Huang ZR, Tipparaju S, Kirpotin DB, Marks JD, Koshkaryev A, Geddie M, Xu L, Lugovosky A, Drummond DC. Abstract 871: Nanoliposomal targeting of ephrin receptor A2 (EphA2): Preclinical in vitro and in vivo rationale Cancer Research. 76: 871-871. DOI: 10.1158/1538-7445.Am2016-871  0.354
2016 Kamoun WS, Oyama S, Kornaga T, Feng T, Luus L, Pham MT, Kirpotin DB, Marks JD, Geddie M, Xu L, Lugovskoy AA, Murphy M, Morrisson C, Drummond DC. Abstract 750: Nanoliposomal targeting of Ephrin receptor A2 (EphA2): Clinical translation: Cancer Research. 76: 750-750. DOI: 10.1158/1538-7445.Am2016-750  0.354
2016 Kirpotin DB, Tipparaju S, Huang ZR, Kamoun WS, Pien C, Kornaga T, Oyama S, Olivier K, Marks JD, Koshkaryev A, Schihl SS, Fetterly G, Schoeberl B, Noble C, Hayes M, et al. Abstract 3912: MM-310, a novel EphA2-targeted docetaxel nanoliposome Cancer Research. 76: 3912-3912. DOI: 10.1158/1538-7445.Am2016-3912  0.346
2016 Koshkaryev A, Fitzgerald J, Kim J, Kalra A, Kamoun W, Blanchette S, Luus L, Klinz S, Alkan O, Kornaga T, Bates S, Pommier Y, Drummond DC. Abstract 2075: Differential tissue clearance results in improved therapeutic index for irinotecan liposome injection (ONIVYDE) when combined with the PARP inhibitor veliparib in preclinical cervical tumors Cancer Research. 76: 2075-2075. DOI: 10.1158/1538-7445.Am2016-2075  0.324
2016 Drummond DC, Straubinger NL, Chaudhuri TR, Moser M, Kamoun WS, Luus L, Huang ZR, Tipparaju S, Gillard B, Morrison C, Repasky E, Kirpotin DB, Straubinger RM. Abstract 2069: Activity of an EphA2-targeted docetaxel nanoliposome in pancreatic patient-derived models as monotherapy and in combination with gemcitabine Cancer Research. 76: 2069-2069. DOI: 10.1158/1538-7445.Am2016-2069  0.329
2016 Peterson T, Kirkpatrick N, Huang Y, Farrar C, Marjit K, Kloepper J, Datta M, Amoozgar Z, Seano G, Jung K, Kamoun W, Vardam T, Snuderl M, Goveia J, Chatterjee S, et al. Tmic-07. Dual Inhibition Of Ang-2 And Vegf Receptors Normalizes Tumor Vasculature And Prolongs Survival In Glioblastoma By Altering Macrophages Neuro-Oncology. 18. DOI: 10.1093/Neuonc/Now212.847  0.367
2015 Datta M, Via LE, Kamoun WS, Liu C, Chen W, Seano G, Weiner DM, Schimel D, England K, Martin JD, Gao X, Xu L, Barry CE, Jain RK. Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery. Proceedings of the National Academy of Sciences of the United States of America. 112: 1827-32. PMID 25624495 DOI: 10.1073/Pnas.1424563112  0.341
2015 Datta M, Via LE, Kamoun WS, Liu C, Chen W, Seano G, Weiner DM, Schimel D, England K, Martin JD, Gao X, Xu L, Barry CE, Jain RK. Abstract B19: Anti-VEGF treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Tumang15-B19  0.356
2014 Kalra AV, Spernyak J, Kim J, Sengooba A, Klinz S, Paz N, Cain J, Kamoun W, Straubinger N, Qu Y, Trueman S, Bayever E, Nielsen U, Drummond D, Fitzgerald J, et al. Abstract 2065: Magnetic resonance imaging with an iron oxide nanoparticle demonstrates the preclinical feasibility of predicting intratumoral uptake and activity of MM-398, a nanoliposomal irinotecan (nal-IRI) Cancer Research. 74: 2065-2065. DOI: 10.1158/1538-7445.Am2014-2065  0.326
2013 Samuel R, Daheron L, Liao S, Vardam T, Kamoun WS, Batista A, Buecker C, Schäfer R, Han X, Au P, Scadden DT, Duda DG, Fukumura D, Jain RK. Generation of functionally competent and durable engineered blood vessels from human induced pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 12774-9. PMID 23861493 DOI: 10.1073/Pnas.1310675110  0.355
2013 Snuderl M, Batista A, Kirkpatrick ND, Ruiz de Almodovar C, Riedemann L, Walsh EC, Anolik R, Huang Y, Martin JD, Kamoun W, Knevels E, Schmidt T, Farrar CT, Vakoc BJ, Mohan N, et al. Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell. 152: 1065-76. PMID 23452854 DOI: 10.1016/J.Cell.2013.01.036  0.363
2012 Kodack DP, Chung E, Yamashita H, Incio J, Duyverman AM, Song Y, Farrar CT, Huang Y, Ager E, Kamoun W, Goel S, Snuderl M, Lussiez A, Hiddingh L, Mahmood S, et al. Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases. Proceedings of the National Academy of Sciences of the United States of America. 109: E3119-27. PMID 23071298 DOI: 10.1073/Pnas.1216078109  0.311
2012 Huang Y, Yuan J, Righi E, Kamoun WS, Ancukiewicz M, Nezivar J, Santosuosso M, Martin JD, Martin MR, Vianello F, Leblanc P, Munn LL, Huang P, Duda DG, Fukumura D, et al. Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. 109: 17561-6. PMID 23045683 DOI: 10.1073/Pnas.1215397109  0.359
2012 Chauhan VP, Stylianopoulos T, Martin JD, Popovi? Z, Chen O, Kamoun WS, Bawendi MG, Fukumura D, Jain RK. Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner. Nature Nanotechnology. 7: 383-8. PMID 22484912 DOI: 10.1038/Nnano.2012.45  0.301
2012 Kodack D, Chung E, Yamashita H, Incio J, Peters A, Song Y, Ager E, Huang Y, Farrar C, Lussiez A, Goel S, Snuderl M, Kamoun W, Hiddingh L, Tannous B, et al. Abstract P3-12-03: Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases. Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P3-12-03  0.326
2011 Liu J, Liao S, Huang Y, Samuel R, Shi T, Naxerova K, Huang P, Kamoun W, Jain RK, Fukumura D, Xu L. PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3638-48. PMID 21459800 DOI: 10.1158/1078-0432.Ccr-10-2456  0.301
2011 Farrar CT, Kamoun WS, Ley CD, Kim YR, Catana C, Kwon SJ, Rosen BR, Jain RK, Sorensen AG. Sensitivity of MRI tumor biomarkers to VEGFR inhibitor therapy in an orthotopic mouse glioma model. Plos One. 6: e17228. PMID 21390238 DOI: 10.1371/Journal.Pone.0017228  0.361
2011 Hiratsuka S, Goel S, Kamoun WS, Maru Y, Fukumura D, Duda DG, Jain RK. Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation. Proceedings of the National Academy of Sciences of the United States of America. 108: 3725-30. PMID 21321210 DOI: 10.1073/Pnas.1100446108  0.354
2011 Baish JW, Stylianopoulos T, Lanning RM, Kamoun WS, Fukumura D, Munn LL, Jain RK. Scaling rules for diffusive drug delivery in tumor and normal tissues. Proceedings of the National Academy of Sciences of the United States of America. 108: 1799-803. PMID 21224417 DOI: 10.1073/Pnas.1018154108  0.347
2011 di Tomaso E, Snuderl M, Kamoun WS, Duda DG, Auluck PK, Fazlollahi L, Andronesi OC, Frosch MP, Wen PY, Plotkin SR, Hedley-Whyte ET, Sorensen AG, Batchelor TT, Jain RK. Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape. Cancer Research. 71: 19-28. PMID 21199795 DOI: 10.1158/0008-5472.Can-10-2602  0.393
2010 Kozin SV, Kamoun WS, Huang Y, Dawson MR, Jain RK, Duda DG. Recruitment of myeloid but not endothelial precursor cells facilitates tumor regrowth after local irradiation. Cancer Research. 70: 5679-85. PMID 20631066 DOI: 10.1158/0008-5472.Can-09-4446  0.37
2010 Kamoun WS, Chae SS, Lacorre DA, Tyrrell JA, Mitre M, Gillissen MA, Fukumura D, Jain RK, Munn LL. Simultaneous measurement of RBC velocity, flux, hematocrit and shear rate in vascular networks. Nature Methods. 7: 655-60. PMID 20581828 DOI: 10.1038/Nmeth.1475  0.332
2010 Chae SS, Kamoun WS, Farrar CT, Kirkpatrick ND, Niemeyer E, de Graaf AM, Sorensen AG, Munn LL, Jain RK, Fukumura D. Angiopoietin-2 interferes with anti-VEGFR2-induced vessel normalization and survival benefit in mice bearing gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 3618-27. PMID 20501615 DOI: 10.1158/1078-0432.Ccr-09-3073  0.388
2010 Wong HK, Lahdenranta J, Kamoun WS, Chan AW, McClatchey AI, Plotkin SR, Jain RK, di Tomaso E. Anti-vascular endothelial growth factor therapies as a novel therapeutic approach to treating neurofibromatosis-related tumors. Cancer Research. 70: 3483-93. PMID 20406973 DOI: 10.1158/0008-5472.Can-09-3107  0.394
2010 Farrar CT, Kamoun WS, Ley CD, Kim YR, Kwon SJ, Dai G, Rosen BR, di Tomaso E, Jain RK, Sorensen AG. In vivo validation of MRI vessel caliber index measurement methods with intravital optical microscopy in a U87 mouse brain tumor model. Neuro-Oncology. 12: 341-50. PMID 20308312 DOI: 10.1093/Neuonc/Nop032  0.33
2010 Snuderl M, Kirkpatrick ND, Walsh EC, Chung E, Kamoun WS, Peterson TE, Munn LL, Duda DG, Fukumura D, Carmeliet P, Xu L, Jain RK. Abstract LB-363: Inhibition of placental growth factor (PlGF) leads to regression of medulloblastoma Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-363  0.391
2009 di Tomaso E, London N, Fuja D, Logie J, Tyrrell JA, Kamoun W, Munn LL, Jain RK. PDGF-C induces maturation of blood vessels in a model of glioblastoma and attenuates the response to anti-VEGF treatment. Plos One. 4: e5123. PMID 19352490 DOI: 10.1371/Journal.Pone.0005123  0.388
2009 Kamoun WS, Ley CD, Farrar CT, Duyverman AM, Lahdenranta J, Lacorre DA, Batchelor TT, di Tomaso E, Duda DG, Munn LL, Fukumura D, Sorensen AG, Jain RK. Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 2542-52. PMID 19332720 DOI: 10.1200/Jco.2008.19.9356  0.372
2008 Kamoun WS, Schmugge SJ, Kraftchick JP, Clemens MG, Shin MC. Liver microcirculation analysis by red blood cell motion modeling in intravital microscopy images. Ieee Transactions On Bio-Medical Engineering. 55: 162-70. PMID 18232358 DOI: 10.1109/Tbme.2007.910670  0.495
2006 Karaa A, Kamoun WS, Xu H, Zhang J, Clemens MG. Differential effects of oxidative stress on hepatic endothelial and Kupffer cell eicosanoid release in response to endothelin-1. Microcirculation (New York, N.Y. : 1994). 13: 457-66. PMID 16864412 DOI: 10.1080/10739680600776278  0.549
2006 Kamoun WS, Karaa A, Kresge N, Merkel SM, Korneszczuk K, Clemens MG. LPS inhibits endothelin-1-induced endothelial NOS activation in hepatic sinusoidal cells through a negative feedback involving caveolin-1. Hepatology (Baltimore, Md.). 43: 182-90. PMID 16374854 DOI: 10.1002/Hep.20940  0.692
2006 Karaa A, Kamoun W, Bryson J, Hamid N, Clemens M. HEPATOCYTES AND ENDOTHELIAL CELLS FUNCTIONAL ASSESSMENT IN PRECISION CUT LIVER SLICES. Shock. 25: 95. DOI: 10.1097/00024382-200606001-00286  0.544
2005 Karaa A, Kamoun WS, Clemens MG. Oxidative stress disrupts nitric oxide synthase activation in liver endothelial cells. Free Radical Biology & Medicine. 39: 1320-31. PMID 16257641 DOI: 10.1016/J.Freeradbiomed.2005.06.014  0.575
2005 Karaa A, Kamoun WS, Clemens MG. Chronic ethanol sensitizes the liver to endotoxin via effects on endothelial nitric oxide synthase regulation. Shock (Augusta, Ga.). 24: 447-54. PMID 16247331 DOI: 10.1097/01.Shk.0000180616.13941.7D  0.547
2005 Kamoun WS, Shin MC, Keller S, Karaa A, Huynh T, Clemens MG. Induction of biphasic changes in perfusion heterogeneity of rat liver after sequential stress in vivo. Shock (Augusta, Ga.). 24: 324-31. PMID 16205316 DOI: 10.1097/01.Shk.0000180618.98692.Ee  0.53
2005 Merkel SM, Kamoun W, Karaa A, Korneszczuk K, Schrum LW, Clemens MG. LPS inhibits endothelin-1-mediated eNOS translocation to the cell membrane in sinusoidal endothelial cells. Microcirculation (New York, N.Y. : 1994). 12: 433-42. PMID 16020391 DOI: 10.1080/10739680590960377  0.696
2005 Kamoun WS, Shin MC, Karaa A, Clemens MG. Quantification of hepatic microcirculation heterogeneity of perfusion: effects of endothelin-1. Microvascular Research. 69: 180-6. PMID 15896361 DOI: 10.1016/J.Mvr.2005.03.003  0.502
2004 Karaa A, Kamoun WS, Thompson KJ, Schrum LW, Clemens MG. Chronic Alcohol Consumption Upregulates Caveolin-1 and Sensitizes the Liver Microcirculation to Endotoxin Shock. 21: 65. DOI: 10.1097/00024382-200406002-00192  0.484
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