| Year |
Citation |
Score |
| 2024 |
Doerfler R, Yerneni S, Newby A, Chaudhary N, Shu A, Fein K, Hofstatter Azambuja J, Whitehead KA. Characterization and comparison of human and mouse milk cells. Plos One. 19: e0297821. PMID 38295101 DOI: 10.1371/journal.pone.0297821 |
0.76 |
|
| 2023 |
Strelkova Petersen DM, Chaudhary N, Arral ML, Weiss RM, Whitehead KA. The mixing method used to formulate lipid nanoparticles affects mRNA delivery efficacy and organ tropism. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 192: 126-135. PMID 37838143 DOI: 10.1016/j.ejpb.2023.10.006 |
0.638 |
|
| 2023 |
Friis KP, Gracin S, Oag S, Leijon A, Sand E, Lindberg B, Lázaro-Ibáñez E, Lindqvist J, Whitehead KA, Bak A. Spray dried lipid nanoparticle formulations enable intratracheal delivery of mRNA. Journal of Controlled Release : Official Journal of the Controlled Release Society. 363: 389-401. PMID 37741463 DOI: 10.1016/j.jconrel.2023.09.031 |
0.812 |
|
| 2023 |
Fein KC, Arral ML, Kim JS, Newby AN, Whitehead KA. Placental drug transport and fetal exposure during pregnancy is determined by drug molecular size, chemistry, and conformation. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 37473809 DOI: 10.1016/j.jconrel.2023.07.029 |
0.781 |
|
| 2023 |
Melamed JR, Yerneni SS, Arral ML, LoPresti ST, Chaudhary N, Sehrawat A, Muramatsu H, Alameh MG, Pardi N, Weissman D, Gittes GK, Whitehead KA. Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer. Science Advances. 9: eade1444. PMID 36706177 DOI: 10.1126/sciadv.ade1444 |
0.777 |
|
| 2022 |
Fein KC, Gleeson JP, Cochran K, Lamson NG, Doerfler R, Melamed JR, Whitehead KA. Long-term daily oral administration of intestinal permeation enhancers is safe and effective in mice. Bioengineering & Translational Medicine. 8: e10342. PMID 36684095 DOI: 10.1002/btm2.10342 |
0.787 |
|
| 2022 |
Doerfler R, Melamed JR, Whitehead KA. The Effect of Infant Gastric Digestion on Human Maternal Milk Cells. Molecular Nutrition & Food Research. e2200090. PMID 35984112 DOI: 10.1002/mnfr.202200090 |
0.718 |
|
| 2022 |
Lamson NG, Fein KC, Gleeson JP, Newby AN, Xian S, Cochran K, Chaudhary N, Melamed JR, Ball RL, Suri K, Ahuja V, Zhang A, Berger A, Kolodieznyi D, Schmidt BF, ... ... Whitehead KA, et al. The strawberry-derived permeation enhancer pelargonidin enables oral protein delivery. Proceedings of the National Academy of Sciences of the United States of America. 119: e2207829119. PMID 35943988 DOI: 10.1073/pnas.2207829119 |
0.783 |
|
| 2022 |
Gleeson JP, Chaudhary N, Fein KC, Doerfler R, Hredzak-Showalter P, Whitehead KA. Profiling of mature-stage human breast milk cells identifies six unique lactocyte subpopulations. Science Advances. 8: eabm6865. PMID 35767604 DOI: 10.1126/sciadv.abm6865 |
0.773 |
|
| 2021 |
Fein KC, Gleeson JP, Newby AN, Whitehead KA. Intestinal permeation enhancers enable oral delivery of macromolecules up to 70 kDa in size. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 34879228 DOI: 10.1016/j.ejpb.2021.11.010 |
0.809 |
|
| 2021 |
Melamed JR, Hajj KA, Chaudhary N, Strelkova D, Arral ML, Pardi N, Alameh MG, Miller JB, Farbiak L, Siegwart DJ, Weissman D, Whitehead KA. Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 34801660 DOI: 10.1016/j.jconrel.2021.11.022 |
0.801 |
|
| 2021 |
Gleeson JP, Fein KC, Whitehead KA. Oral delivery of peptide therapeutics in infants: Challenges and opportunities. Advanced Drug Delivery Reviews. PMID 33774115 DOI: 10.1016/j.addr.2021.03.011 |
0.789 |
|
| 2020 |
Cheng YW, Shiwarski DJ, Ball RL, Whitehead KA, Feinberg AW. Engineering Aligned Skeletal Muscle Tissue Using Decellularized Plant-Derived Scaffolds. Acs Biomaterials Science & Engineering. 6: 3046-3054. PMID 33463300 DOI: 10.1021/acsbiomaterials.0c00058 |
0.701 |
|
| 2020 |
Zheng S, Lavrenyuk K, Lamson NG, Fein KC, Whitehead KA, Dahl KN. Piperazine Derivatives Enhance Epithelial Cell Monolayer Permeability by Increased Cell Force Generation and Loss of Cadherin Structures. Acs Biomaterials Science & Engineering. 6: 367-374. PMID 33463243 DOI: 10.1021/acsbiomaterials.9b01660 |
0.798 |
|
| 2020 |
Gleeson JP, Fein KC, Chaudhary N, Doerfler R, Newby AN, Whitehead KA. The enhanced intestinal permeability of infant mice enables oral protein and macromolecular absorption without delivery technology. International Journal of Pharmaceutics. 593: 120120. PMID 33249250 DOI: 10.1016/j.ijpharm.2020.120120 |
0.808 |
|
| 2020 |
Hajj KA, Melamed JR, Chaudhary N, Lamson NG, Ball RL, Yerneni SS, Whitehead KA. A potent branched-tail lipid nanoparticle enables multiplexed mRNA delivery and gene editing in vivo. Nano Letters. PMID 32496069 DOI: 10.1021/Acs.Nanolett.0C00596 |
0.78 |
|
| 2020 |
Cochran KE, Lamson NG, Whitehead KA. Expanding the utility of the dextran sulfate sodium (DSS) mouse model to induce a clinically relevant loss of intestinal barrier function. Peerj. 8: e8681. PMID 32195049 DOI: 10.7717/Peerj.8681 |
0.78 |
|
| 2020 |
Cheng Y, Shiwarski DJ, Ball RL, Whitehead KA, Feinberg AW. Engineering Aligned Skeletal Muscle Tissue Using Decellularized Plant-Derived Scaffolds Acs Biomaterials Science & Engineering. 6: 3046-3054. DOI: 10.1021/Acsbiomaterials.0C00058 |
0.707 |
|
| 2019 |
Lamson NG, Berger A, Fein KC, Whitehead KA. Anionic nanoparticles enable the oral delivery of proteins by enhancing intestinal permeability. Nature Biomedical Engineering. PMID 31686002 DOI: 10.1038/S41551-019-0465-5 |
0.806 |
|
| 2019 |
Lamson NG, Ball RL, Fein KC, Whitehead KA. Thrifty, Rapid Intestinal Monolayers (TRIM) Using Caco-2 Epithelial Cells for Oral Drug Delivery Experiments. Pharmaceutical Research. 36: 172. PMID 31659456 DOI: 10.1007/S11095-019-2712-6 |
0.794 |
|
| 2019 |
Levy ES, Samy KE, Lamson NG, Whitehead KA, Kroetz DL, Desai TA. Reversible Inhibition of Efflux Transporters by Hydrogel Microdevices. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 31639417 DOI: 10.1016/J.Ejpb.2019.10.007 |
0.795 |
|
| 2019 |
He J, Hajj KA, Knapp CM, Whitehead KA. Development of a clinically relevant chemoresistant mantle cell lymphoma cell culture model. Experimental Biology and Medicine (Maywood, N.J.). 1535370219857594. PMID 31208205 DOI: 10.1177/1535370219857594 |
0.754 |
|
| 2019 |
Kasiewicz LN, Whitehead KA. Lipid nanoparticles silence tumor necrosis factor α to improve wound healing in diabetic mice. Bioengineering & Translational Medicine. 4: 75-82. PMID 30680320 DOI: 10.1002/btm2.10123 |
0.781 |
|
| 2019 |
Hajj KA, Ball RL, Deluty SB, Singh SR, Strelkova D, Knapp CM, Whitehead KA. Branched-Tail Lipid Nanoparticles Potently Deliver mRNA In Vivo due to Enhanced Ionization at Endosomal pH. Small (Weinheim An Der Bergstrasse, Germany). e1805097. PMID 30637934 DOI: 10.1002/Smll.201805097 |
0.784 |
|
| 2019 |
Brown TD, Whitehead KA, Mitragotri S. Materials for oral delivery of proteins and peptides Nature Reviews Materials. 5: 127-148. DOI: 10.1038/S41578-019-0156-6 |
0.69 |
|
| 2019 |
Zheng S, Lavrenyuk K, Lamson NG, Fein KC, Whitehead KA, Dahl KN. Piperazine Derivatives Enhance Epithelial Cell Monolayer Permeability by Increased Cell Force Generation and Loss of Cadherin Structures Acs Biomaterials Science & Engineering. 6: 367-374. DOI: 10.1021/Acsbiomaterials.9B01660 |
0.793 |
|
| 2018 |
Knapp CM, He J, Lister J, Whitehead KA. Lipid nanoparticle siRNA cocktails for the treatment of mantle cell lymphoma. Bioengineering & Translational Medicine. 3: 138-147. PMID 30065968 DOI: 10.1002/btm2.10088 |
0.742 |
|
| 2018 |
Ball RL, Hajj KA, Vizelman J, Bajaj P, Whitehead KA. Lipid nanoparticle formulations for enhanced co-delivery of siRNA and mRNA. Nano Letters. PMID 29694050 DOI: 10.1021/Acs.Nanolett.8B01101 |
0.808 |
|
| 2018 |
Ball RL, Bajaj P, Whitehead KA. Oral delivery of siRNA lipid nanoparticles: Fate in the GI tract. Scientific Reports. 8: 2178. PMID 29391566 DOI: 10.1038/S41598-018-20632-6 |
0.799 |
|
| 2017 |
Kasiewicz LN, Whitehead KA. Recent advances in biomaterials for the treatment of diabetic foot ulcers. Biomaterials Science. PMID 28829074 DOI: 10.1039/C7Bm00264E |
0.772 |
|
| 2017 |
Cummings CS, Fein K, Murata H, Ball RL, Russell AJ, Whitehead KA. ATRP-grown protein-polymer conjugates containing phenylpiperazine selectively enhance transepithelial protein transport. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28455168 DOI: 10.1016/J.Jconrel.2017.04.035 |
0.782 |
|
| 2017 |
Fein KC, Lamson NG, Whitehead KA. Structure-Function Analysis of Phenylpiperazine Derivatives as Intestinal Permeation Enhancers. Pharmaceutical Research. PMID 28374339 DOI: 10.1007/S11095-017-2149-8 |
0.79 |
|
| 2017 |
Ball RL, Bajaj P, Whitehead KA. Achieving long-term stability of lipid nanoparticles: examining the effect of pH, temperature, and lyophilization. International Journal of Nanomedicine. 12: 305-315. PMID 28115848 DOI: 10.2147/Ijn.S123062 |
0.757 |
|
| 2017 |
Hajj KA, Whitehead KA. Tools for translation: non-viral materials for therapeutic mRNA delivery Nature Reviews Materials. 2: 17056. DOI: 10.1038/Natrevmats.2017.56 |
0.793 |
|
| 2016 |
Whitehead KA. A new lease on half-life. Science Translational Medicine. 8: 369ec201. PMID 27974661 DOI: 10.1126/Scitranslmed.Aal3699 |
0.346 |
|
| 2016 |
Knapp CM, He J, Lister J, Whitehead KA. Lipidoid nanoparticle mediated silencing of Mcl-1 induces apoptosis in mantle cell lymphoma. Experimental Biology and Medicine (Maywood, N.J.). PMID 27022142 DOI: 10.1177/1535370216640944 |
0.758 |
|
| 2016 |
Lamson NG, Cusimano G, Suri K, Zhang A, Whitehead KA. The pH of Piperazine Derivative Solutions Predicts Their Utility as Transepithelial Permeation Enhancers. Molecular Pharmaceutics. PMID 26730955 DOI: 10.1021/Acs.Molpharmaceut.5B00803 |
0.798 |
|
| 2016 |
Whitehead KA. Gobbling up inflammation to ameliorate autoimmunity Science Translational Medicine. 8: 355ec145-355ec145. DOI: 10.1126/Scitranslmed.Aah6435 |
0.314 |
|
| 2016 |
Whitehead KA. A captive peptide for T cell activation Science Translational Medicine. 8. DOI: 10.1126/Scitranslmed.Aah4508 |
0.337 |
|
| 2016 |
Knapp CM, Guo P, Whitehead KA. Lipidoid Tail Structure Strongly Influences siRNA Delivery Activity Cellular and Molecular Bioengineering. 1-10. DOI: 10.1007/S12195-016-0436-9 |
0.793 |
|
| 2015 |
Kasiewicz LN, Whitehead KA. Silencing TNFα with lipidoid nanoparticles downregulates both TNFα and MCP-1 in an in vitro co-culture model of diabetic foot ulcers. Acta Biomaterialia. PMID 26689461 DOI: 10.1016/J.Actbio.2015.12.023 |
0.792 |
|
| 2015 |
Ball RL, Knapp CM, Whitehead KA. Lipidoid Nanoparticles for siRNA Delivery to the Intestinal Epithelium: In Vitro Investigations in a Caco-2 Model. Plos One. 10: e0133154. PMID 26192592 DOI: 10.1371/Journal.Pone.0133154 |
0.825 |
|
| 2015 |
Veiseh O, Tang BC, Whitehead KA, Anderson DG, Langer R. Managing diabetes with nanomedicine: challenges and opportunities. Nature Reviews. Drug Discovery. 14: 45-57. PMID 25430866 DOI: 10.1038/Nrd4477 |
0.59 |
|
| 2014 |
Knapp CM, Whitehead KA. In pursuit of a moving target: nanotherapeutics for the treatment of non-Hodgkin B-cell lymphoma. Expert Opinion On Drug Delivery. 11: 1923-37. PMID 25244254 DOI: 10.1517/17425247.2014.945419 |
0.718 |
|
| 2014 |
Whitehead KA, Dorkin JR, Vegas AJ, Chang PH, Veiseh O, Matthews J, Fenton OS, Zhang Y, Olejnik KT, Yesilyurt V, Chen D, Barros S, Klebanov B, Novobrantseva T, Langer R, et al. Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity. Nature Communications. 5: 4277. PMID 24969323 DOI: 10.1038/Ncomms5277 |
0.82 |
|
| 2013 |
Mizrahi B, Shankarappa SA, Hickey JM, Dohlman JC, Timko BP, Whitehead KA, Lee JJ, Langer R, Anderson DG, Kohane DS. A Stiff Injectable Biodegradable Elastomer. Advanced Functional Materials. 23: 1527-1533. PMID 23667350 DOI: 10.1002/Adfm.201202433 |
0.771 |
|
| 2012 |
Whitehead KA, Matthews J, Chang PH, Niroui F, Dorkin JR, Severgnini M, Anderson DG. In vitro-in vivo translation of lipid nanoparticles for hepatocellular siRNA delivery. Acs Nano. 6: 6922-9. PMID 22770391 DOI: 10.1021/Nn301922X |
0.553 |
|
| 2012 |
Chen D, Love KT, Chen Y, Eltoukhy AA, Kastrup C, Sahay G, Jeon A, Dong Y, Whitehead KA, Anderson DG. Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation. Journal of the American Chemical Society. 134: 6948-51. PMID 22475086 DOI: 10.1021/Ja301621Z |
0.725 |
|
| 2012 |
Kanasty RL, Whitehead KA, Vegas AJ, Anderson DG. Action and reaction: the biological response to siRNA and its delivery vehicles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 513-24. PMID 22252451 DOI: 10.1038/Mt.2011.294 |
0.762 |
|
| 2011 |
Whitehead KA, Dahlman JE, Langer RS, Anderson DG. Silencing or stimulation? siRNA delivery and the immune system. Annual Review of Chemical and Biomolecular Engineering. 2: 77-96. PMID 22432611 DOI: 10.1146/Annurev-Chembioeng-061010-114133 |
0.587 |
|
| 2011 |
Siegwart DJ, Whitehead KA, Nuhn L, Sahay G, Cheng H, Jiang S, Ma M, Lytton-Jean A, Vegas A, Fenton P, Levins CG, Love KT, Lee H, Cortez C, Collins SP, et al. Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery. Proceedings of the National Academy of Sciences of the United States of America. 108: 12996-3001. PMID 21784981 DOI: 10.1073/Pnas.1106379108 |
0.796 |
|
| 2011 |
Whitehead KA, Sahay G, Li GZ, Love KT, Alabi CA, Ma M, Zurenko C, Querbes W, Langer RS, Anderson DG. Synergistic silencing: combinations of lipid-like materials for efficacious siRNA delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1688-94. PMID 21750531 DOI: 10.1038/Mt.2011.141 |
0.765 |
|
| 2011 |
Timko BP, Whitehead K, Gao W, Kohane DS, Farokhzad O, Anderson D, Langer R. Advances in drug delivery Annual Review of Materials Research. 41: 1-20. DOI: 10.1146/annurev-matsci-062910-100359 |
0.777 |
|
| 2010 |
Mahon KP, Love KT, Whitehead KA, Qin J, Akinc A, Leshchiner E, Leshchiner I, Langer R, Anderson DG. Combinatorial approach to determine functional group effects on lipidoid-mediated siRNA delivery. Bioconjugate Chemistry. 21: 1448-54. PMID 20715849 DOI: 10.1021/Bc100041R |
0.65 |
|
| 2010 |
Cheng H, Kastrup CJ, Ramanathan R, Siegwart DJ, Ma M, Bogatyrev SR, Xu Q, Whitehead KA, Langer R, Anderson DG. Nanoparticulate cellular patches for cell-mediated tumoritropic delivery. Acs Nano. 4: 625-31. PMID 20121215 DOI: 10.1021/Nn901319Y |
0.624 |
|
| 2010 |
Love KT, Mahon KP, Levins CG, Whitehead KA, Querbes W, Dorkin JR, Qin J, Cantley W, Qin LL, Racie T, Frank-Kamenetsky M, Yip KN, Alvarez R, Sah DW, de Fougerolles A, et al. Lipid-like materials for low-dose, in vivo gene silencing. Proceedings of the National Academy of Sciences of the United States of America. 107: 1864-9. PMID 20080679 DOI: 10.1073/Pnas.0910603106 |
0.625 |
|
| 2010 |
Love KT, Mahon KP, Levins CG, Whitehead KA, Querbes W, Dorkin JR, Qin J, Cantley W, Qin LL, Racie T, Frank-Kamenetsky M, Yip KN, Alvarez R, Sah DWY, De Fougerolles A, et al. Lipid-like materials for low-dose, in vivo gene silencing (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 5 (1864-1869)) DOI:10.1073/pnas.0910603106 Proceedings of the National Academy of Sciences of the United States of America. 107: 9915. DOI: 10.1073/pnas.1005136107 |
0.337 |
|
| 2010 |
Whitehead KA, Langer R, Anderson DG. Knocking down barriers: Advances in siRNA delivery (Nature Reviews Drug Discovery (2009) 8 (129-138) DOI:10.1038/nrd2742) Nature Reviews Drug Discovery. 9: 412. DOI: 10.1038/nrd3182 |
0.587 |
|
| 2009 |
Whitehead KA, Langer R, Anderson DG. Knocking down barriers: advances in siRNA delivery. Nature Reviews. Drug Discovery. 8: 129-38. PMID 19180106 DOI: 10.1038/Nrd2742 |
0.637 |
|
| 2009 |
Whitehead KA, Langer R, Anderson DG. Erratum: Knocking down barriers: advances in siRNA delivery Nature Reviews Drug Discovery. 8: 516-516. DOI: 10.1038/Nrd2919-C1 |
0.573 |
|
| 2008 |
Whitehead K, Karr N, Mitragotri S. Discovery of synergistic permeation enhancers for oral drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 128: 128-33. PMID 18433909 DOI: 10.1016/J.Jconrel.2008.03.005 |
0.707 |
|
| 2008 |
Whitehead K, Mitragotri S. Mechanistic analysis of chemical permeation enhancers for oral drug delivery. Pharmaceutical Research. 25: 1412-9. PMID 18311478 DOI: 10.1007/S11095-008-9542-2 |
0.69 |
|
| 2008 |
Whitehead K, Karr N, Mitragotri S. Safe and effective permeation enhancers for oral drug delivery. Pharmaceutical Research. 25: 1782-8. PMID 18058001 DOI: 10.1007/S11095-007-9488-9 |
0.691 |
|
| 2004 |
Whitehead K, Shen Z, Mitragotri S. Oral delivery of macromolecules using intestinal patches: applications for insulin delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 98: 37-45. PMID 15245887 DOI: 10.1016/J.Jconrel.2004.04.013 |
0.65 |
|
| Show low-probability matches. |