Xinshu Grace Xiao, Ph.D - Publications

Affiliations: 
2009- Bioinformatics University of California, Los Angeles, Los Angeles, CA 
Area:
RNA, Computational Biology, Bioinformatics
Website:
https://www.ibp.ucla.edu/research/xiao/Home.html

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Yamamoto R, Liu Z, Choudhury M, Xiao X. dsRID: in silico identification of dsRNA regions using long-read RNA-seq data. Bioinformatics (Oxford, England). PMID 37871161 DOI: 10.1093/bioinformatics/btad649  0.301
2023 Liu Z, Quinones-Valdez G, Fu T, Huang E, Choudhury M, Reese F, Mortazavi A, Xiao X. L-GIREMI uncovers RNA editing sites in long-read RNA-seq. Genome Biology. 24: 171. PMID 37474948 DOI: 10.1186/s13059-023-03012-w  0.401
2023 Yamamoto R, Liu Z, Choudhury M, Xiao X. dsRID: Editing-free in silico identification of dsRNA region using long-read RNA-seq data. Biorxiv : the Preprint Server For Biology. PMID 37333092 DOI: 10.1101/2023.06.02.543466  0.384
2023 Choudhury M, Fu T, Amoah K, Jun HI, Chan TW, Park S, Walker DW, Bahn JH, Xiao X. Widespread RNA hypoediting in schizophrenia and its relevance to mitochondrial function. Science Advances. 9: eade9997. PMID 37027465 DOI: 10.1126/sciadv.ade9997  0.343
2023 Zheng R, Dunlap M, Lyu J, Gonzalez-Figueroa C, Bobkov G, Harvey SE, Chan TW, Quinones-Valdez G, Choudhury M, Vuong A, Flynn RA, Chang HY, Xiao X, Cheng C. LINE-associated cryptic splicing induces dsRNA-mediated interferon response and tumor immunity. Biorxiv : the Preprint Server For Biology. PMID 36865202 DOI: 10.1101/2023.02.23.529804  0.358
2022 Chan TW, Dodson JP, Arbet J, Boutros PC, Xiao X. Single-cell analysis in lung adenocarcinoma implicates RNA editing in cancer innate immunity and patient prognosis. Cancer Research. PMID 36449563 DOI: 10.1158/0008-5472.CAN-22-1062  0.336
2022 Quinones-Valdez G, Fu T, Chan TW, Xiao X. scAllele: A versatile tool for the detection and analysis of variants in scRNA-seq. Science Advances. 8: eabn6398. PMID 36054357 DOI: 10.1126/sciadv.abn6398  0.329
2022 Fu T, Chan TW, Bahn JH, Kim TH, Rowat AC, Xiao X. Multifaceted role of RNA editing in promoting loss-of-function of PODXL in cancer. Iscience. 25: 104836. PMID 35992085 DOI: 10.1016/j.isci.2022.104836  0.425
2022 He J, Fu T, Zhang L, Wanrong Gao L, Rensel M, Remage-Healey L, White SA, Gedman G, Whitelegge J, Xiao X, Schlinger BA. Improved Zebra Finch Brain Transcriptome identifies novel proteins with sex differences. Gene. 146803. PMID 35961439 DOI: 10.1016/j.gene.2022.146803  0.316
2021 Wang H, Chan TW, Vashisht AA, Drew BG, Calkin AC, Harris TE, Wohlschlegel JA, Xiao X, Reue K. Lipin 1 modulates mRNA splicing during fasting adaptation in liver. Jci Insight. 6. PMID 34494556 DOI: 10.1172/jci.insight.150114  0.336
2021 Amoah K, Hsiao YE, Bahn JH, Sun Y, Burghard C, Tan BX, Yang EW, Xiao X. Allele-specific alternative splicing and its functional genetic variants in human tissues. Genome Research. PMID 33452016 DOI: 10.1101/gr.265637.120  0.312
2020 Chan TW, Fu T, Bahn JH, Jun HI, Lee JH, Quinones-Valdez G, Cheng C, Xiao X. RNA editing in cancer impacts mRNA abundance in immune response pathways. Genome Biology. 21: 268. PMID 33106178 DOI: 10.1186/s13059-020-02171-4  0.426
2020 Tran SS, Zhou Q, Xiao X. Statistical inference of differential RNA editing sites from RNA-sequencing data by hierarchical modeling. Bioinformatics (Oxford, England). PMID 32003773 DOI: 10.1093/Bioinformatics/Btaa066  0.502
2019 Cass AA, Xiao X. mountainClimber Identifies Alternative Transcription Start and Polyadenylation Sites in RNA-Seq. Cell Systems. PMID 31542416 DOI: 10.1016/J.Cels.2019.07.011  0.547
2019 Arefeen A, Xiao X, Jiang T. DeepPASTA: deep neural network based polyadenylation site analysis. Bioinformatics (Oxford, England). PMID 31081512 DOI: 10.1093/Bioinformatics/Btz283  0.466
2019 Yang EW, Bahn JH, Hsiao EY, Tan BX, Sun Y, Fu T, Zhou B, Van Nostrand EL, Pratt GA, Freese P, Wei X, Quinones-Valdez G, Urban AE, Graveley BR, Burge CB, ... ... Xiao X, et al. Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNA. Nature Communications. 10: 1338. PMID 30902979 DOI: 10.1038/S41467-019-09292-W  0.72
2019 Quinones-Valdez G, Tran SS, Jun HI, Bahn JH, Yang EW, Zhan L, Brümmer A, Wei X, Van Nostrand EL, Pratt GA, Yeo GW, Graveley BR, Xiao X. Regulation of RNA editing by RNA-binding proteins in human cells. Communications Biology. 2: 19. PMID 30652130 DOI: 10.1038/s42003-018-0271-8  0.631
2019 Tran SS, Jun HI, Bahn JH, Azghadi A, Ramaswami G, Van Nostrand EL, Nguyen TB, Hsiao YE, Lee C, Pratt GA, Martínez-Cerdeño V, Hagerman RJ, Yeo GW, Geschwind DH, Xiao X. Widespread RNA editing dysregulation in brains from autistic individuals. Nature Neuroscience. 22: 25-36. PMID 30559470 DOI: 10.1038/S41593-018-0287-X  0.581
2018 Cheung R, Insigne KD, Yao D, Burghard CP, Wang J, Hsiao YE, Jones EM, Goodman DB, Xiao X, Kosuri S. A Multiplexed Assay for Exon Recognition Reveals that an Unappreciated Fraction of Rare Genetic Variants Cause Large-Effect Splicing Disruptions. Molecular Cell. PMID 30503770 DOI: 10.1016/J.Molcel.2018.10.037  0.388
2018 Arefeen A, Liu J, Xiao X, Jiang T. TAPAS: tool for alternative polyadenylation site analysis. Bioinformatics (Oxford, England). 34: 2521-2529. PMID 30052912 DOI: 10.1093/Bioinformatics/Bty110  0.442
2018 Harvey SE, Xu Y, Lin X, Gao XD, Qiu Y, Ahn J, Xiao X, Cheng C. Co-regulation of alternative splicing by hnRNPM and ESRP1 during EMT. Rna (New York, N.Y.). PMID 30042172 DOI: 10.1261/Rna.066712.118  0.451
2018 Hsiao YE, Bahn JH, Yang Y, Lin X, Tran S, Yang EW, Quinones-Valdez G, Xiao X. RNA editing in nascent RNA affects pre-mRNA splicing. Genome Research. PMID 29724793 DOI: 10.1101/Gr.231209.117  0.532
2018 He X, Li F, Bor B, Koyano K, Cen L, Xiao X, Shi W, Wong DTW. Human tRNA-Derived Small RNAs Modulate Host-Oral Microbial Interactions. Journal of Dental Research. 22034518770605. PMID 29702004 DOI: 10.1177/0022034518770605  0.404
2018 Li F, Kaczor-Urbanowicz KE, Sun J, Majem B, Lo HC, Kim Y, Koyano K, Liu Rao S, Young Kang S, Mi Kim S, Kim KM, Kim S, Chia D, Elashoff D, Grogan TR, ... Xiao X, et al. Characterization of Human Salivary Extracellular RNA by Next-generation Sequencing. Clinical Chemistry. PMID 29685897 DOI: 10.1373/Clinchem.2017.285072  0.494
2017 Brümmer A, Yang Y, Chan TW, Xiao X. Structure-mediated modulation of mRNA abundance by A-to-I editing. Nature Communications. 8: 1255. PMID 29093448 DOI: 10.1038/S41467-017-01459-7  0.524
2017 Kaczor-Urbanowicz KE, Kim Y, Li F, Galeev T, Kitchen RR, Koyano K, Jeong SH, Wang X, Elashoff D, Kang SY, Kim SM, Kim K, Kim S, Chia D, Xiao X, et al. Novel approaches for bioinformatic analysis of salivary RNA Sequencing data in the biomarker development process. Bioinformatics (Oxford, England). PMID 28961734 DOI: 10.1093/Bioinformatics/Btx504  0.457
2017 Touma M, Kang X, Gao F, Zhao Y, Cass AA, Biniwale R, Xiao X, Eghbali M, Coppola G, Reemtsen B, Wang Y. Wnt11 regulates cardiac chamber development and disease during perinatal maturation. Jci Insight. 2. PMID 28878122 DOI: 10.1172/Jci.Insight.94904  0.309
2017 Yang Y, Fan X, Mao M, Song X, Wu P, Zhang Y, Jin Y, Yang Y, Chen L, Wang Y, Wong CC, Xiao X, Wang Z. Extensive translation of circular RNAs driven by N(6)-methyladenosine. Cell Research. PMID 28281539 DOI: 10.1038/Cr.2017.31  0.627
2017 Gao C, Hu J, Wei C, Hsiao YE, Ren S, Xue Y, Zhou Y, Zhang J, Chen J, Xiao X, Fu X, Xing Y, Wang Y. Function Beyond RNA Splicing for RBFox Family Members in Heart Journal of Molecular and Cellular Cardiology. 112: 146-147. DOI: 10.1016/J.Yjmcc.2017.07.050  0.41
2016 Hasin-Brumshtein Y, Khan AH, Hormozdiari F, Pan C, Parks BW, Petyuk VA, Piehowski PD, Bruemmer A, Pellegrini M, Xiao X, Eskin E, Smith RD, Lusis AJ, Smith DJ. Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots, splicing QTLs and novel non-coding genes. Elife. 5. PMID 27623010 DOI: 10.7554/Elife.15614  0.422
2016 Wang Z, Zhang XJ, Ji YX, Zhang P, Deng KQ, Gong J, Ren S, Wang X, Chen I, Wang H, Gao C, Yokota T, Ang YS, Li S, Cass A, ... ... Xiao X, et al. The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy. Nature Medicine. PMID 27618650 DOI: 10.1038/Nm.4179  0.372
2016 Touma M, Kang X, Zhao Y, Cass AA, Gao F, Biniwale R, Coppola G, Xiao X, Reemtsen B, Wang Y. Decoding the Long Noncoding RNA during Cardiac Maturation: A Roadmap for Functional Discovery. Circulation. Cardiovascular Genetics. PMID 27591185 DOI: 10.1161/Circgenetics.115.001363  0.401
2016 Cass AA, Bahn JH, Lee JH, Greer C, Lin X, Kim Y, Hsiao YE, Xiao X. Global analyses of endonucleolytic cleavage in mammals reveal expanded repertoires of cleavage-inducing small RNAs and their targets. Nucleic Acids Research. PMID 26975654 DOI: 10.1093/Nar/Gkw164  0.517
2016 Hsiao YE, Bahn JH, Lin X, Chan TM, Wang R, Xiao X. Alternative splicing modulated by genetic variants demonstrates accelerated evolution regulated by highly conserved proteins. Genome Research. PMID 26888265 DOI: 10.1101/Gr.193359.115  0.489
2016 Fuxjager MJ, Lee JH, Chan TM, Bahn JH, Chew JG, Xiao X, Schlinger BA. Research Resource: Hormones, genes and athleticism: effect of androgens on the avian muscular transcriptome. Molecular Endocrinology (Baltimore, Md.). me20151270. PMID 26745669 DOI: 10.1210/Me.2015-1270  0.31
2015 Gao C, Ren S, Lee JH, Qiu J, Chapski DJ, Rau CD, Zhou Y, Abdellatif M, Nakano A, Vondriska TM, Xiao X, Fu XD, Chen JN, Wang Y. RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure. The Journal of Clinical Investigation. PMID 26619120 DOI: 10.1172/Jci84015  0.449
2015 Bhate A, Parker DJ, Bebee TW, Ahn J, Arif W, Rashan EH, Chorghade S, Chau A, Lee JH, Anakk S, Carstens RP, Xiao X, Kalsotra A. ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation. Nature Communications. 6: 8768. PMID 26531099 DOI: 10.1038/Ncomms9768  0.375
2015 Ahn J, Xiao X. RASER: reads aligner for SNPs and editing sites of RNA. Bioinformatics (Oxford, England). PMID 26323713 DOI: 10.1093/Bioinformatics/Btv505  0.402
2015 Bahn JH, Ahn J, Lin X, Zhang Q, Lee JH, Civelek M, Xiao X. Genomic analysis of ADAR1 binding and its involvement in multiple RNA processing pathways. Nature Communications. 6: 6355. PMID 25751603 DOI: 10.1038/Ncomms7355  0.471
2015 Zhang Q, Xiao X. Genome sequence-independent identification of RNA editing sites Nature Methods. 12: 347-350. PMID 25730491 DOI: 10.1038/Nmeth.3314  0.473
2015 Li Z, Yu J, Hosohama L, Nee K, Gkountela S, Chaudhari S, Cass AA, Xiao X, Clark AT. The Sm protein methyltransferase PRMT5 is not required for primordial germ cell specification in mice. The Embo Journal. 34: 748-58. PMID 25519955 DOI: 10.15252/Embj.201489319  0.371
2015 Bahn JH, Zhang Q, Li F, Chan TM, Lin X, Kim Y, Wong DT, Xiao X. The landscape of microRNA, Piwi-interacting RNA, and circular RNA in human saliva. Clinical Chemistry. 61: 221-30. PMID 25376581 DOI: 10.1373/Clinchem.2014.230433  0.437
2014 Xu Y, Gao XD, Lee JH, Huang H, Tan H, Ahn J, Reinke LM, Peter ME, Feng Y, Gius D, Siziopikou KP, Peng J, Xiao X, Cheng C. Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing. Genes & Development. 28: 1191-203. PMID 24840202 DOI: 10.1101/Gad.241968.114  0.363
2013 Chan TM, Lo LY, Sze-To HY, Leung KS, Xiao X, Wong MH. Modeling associated protein-DNA pattern discovery with unified scores. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 10: 696-707. PMID 24091402 DOI: 10.1109/Tcbb.2013.60  0.352
2013 Lee JH, Ang JK, Xiao X. Analysis and design of RNA sequencing experiments for identifying RNA editing and other single-nucleotide variants. Rna (New York, N.Y.). 19: 725-32. PMID 23598527 DOI: 10.1261/Rna.037903.112  0.492
2013 Wang Y, Xiao X, Zhang J, Choudhury R, Robertson A, Li K, Ma M, Burge CB, Wang Z. A complex network of factors with overlapping affinities represses splicing through intronic elements Nature Structural and Molecular Biology. 20: 36-45. PMID 23241926 DOI: 10.1038/Nsmb.2459  0.724
2012 Bass B, Hundley H, Li JB, Peng Z, Pickrell J, Xiao XG, Yang L. The difficult calls in RNA editing. Interviewed by H Craig Mak. Nature Biotechnology. 30: 1207-9. PMID 23222792 DOI: 10.1038/Nbt.2452  0.363
2012 Wang Y, Ma M, Xiao X, Wang Z. Intronic splicing enhancers, cognate splicing factors and context-dependent regulation rules. Nature Structural & Molecular Biology. 19: 1044-52. PMID 22983564 DOI: 10.1038/Nsmb.2377  0.653
2012 Li G, Bahn JH, Lee JH, Peng G, Chen Z, Nelson SF, Xiao X. Identification of allele-specific alternative mRNA processing via transcriptome sequencing. Nucleic Acids Research. 40: e104. PMID 22467206 DOI: 10.1093/Nar/Gks280  0.48
2012 Anderson ES, Lin CH, Xiao X, Stoilov P, Burge CB, Black DL. The cardiotonic steroid digitoxin regulates alternative splicing through depletion of the splicing factors SRSF3 and TRA2B. Rna (New York, N.Y.). 18: 1041-9. PMID 22456266 DOI: 10.1261/Rna.032912.112  0.657
2012 Gomez G, Lee JH, Veldman MB, Lu J, Xiao X, Lin S. Identification of vascular and hematopoietic genes downstream of etsrp by deep sequencing in zebrafish. Plos One. 7: e31658. PMID 22438865 DOI: 10.1371/Journal.Pone.0031658  0.402
2012 Bahn JH, Lee JH, Li G, Greer C, Peng G, Xiao X. Accurate identification of A-to-I RNA editing in human by transcriptome sequencing. Genome Research. 22: 142-50. PMID 21960545 DOI: 10.1101/Gr.124107.111  0.407
2011 Lee JH, Gao C, Peng G, Greer C, Ren S, Wang Y, Xiao X. Analysis of transcriptome complexity through RNA sequencing in normal and failing murine hearts. Circulation Research. 109: 1332-41. PMID 22034492 DOI: 10.1161/Circresaha.111.249433  0.365
2011 Xiao X, Lee JH. Systems analysis of alternative splicing and its regulation. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 2: 550-565. PMID 20836047 DOI: 10.1002/Wsbm.84  0.513
2009 Xiao X, Wang Z, Jang M, Nutiu R, Wang ET, Burge CB. Splice site strength-dependent activity and genetic buffering by poly-G runs Nature Structural and Molecular Biology. 16: 1094-1100. PMID 19749754 DOI: 10.1038/Nsmb.1661  0.745
2008 Kalsotra A, Xiao X, Ward AJ, Castle JC, Johnson JM, Burge CB, Cooper TA. A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart Proceedings of the National Academy of Sciences of the United States of America. 105: 20333-20338. PMID 19075228 DOI: 10.1073/Pnas.0809045105  0.609
2007 Xiao X, Wang Z, Jang M, Burge CB. Coevolutionary networks of splicing cis-regulatory elements Proceedings of the National Academy of Sciences of the United States of America. 104: 18583-18588. PMID 17998536 DOI: 10.1073/Pnas.0707349104  0.714
2007 Calarco JA, Xing Y, Cáceres M, Calarco JP, Xiao X, Pan Q, Lee C, Preuss TM, Blencowe BJ. Global analysis of alternative splicing differences between humans and chimpanzees. Genes & Development. 21: 2963-75. PMID 17978102 DOI: 10.1101/Gad.1606907  0.413
2007 Wang Z, Xiao X, Friedman B, Shomron N, Burge CB. Towards an RNA Splicing Code The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A147-B  0.631
2006 Stadler MB, Shomron N, Yeo GW, Schneider A, Xiao X, Burge CB. Inference of splicing regulatory activities by sequence neighborhood analysis. Plos Genetics. 2: e191. PMID 17121466 DOI: 10.1371/Journal.Pgen.0020191  0.693
2006 Wang Z, Xiao X, Van Nostrand E, Burge CB. General and Specific Functions of Exonic Splicing Silencers in Splicing Control Molecular Cell. 23: 61-70. PMID 16797197 DOI: 10.1016/J.Molcel.2006.05.018  0.704
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