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Louise Scharf, Ph.D. - Publications

Affiliations: 
2010 Biochemistry and Molecular Biology University of Chicago, Chicago, IL 
Area:
Molecular Biology, Biochemistry, Immunology
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Wang H, Gristick HB, Scharf L, West AP, Galimidi RP, Seaman MS, Freund NT, Nussenzweig MC, Bjorkman PJ. Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies. Elife. 6. PMID 28548638 DOI: 10.7554/Elife.27389  0.413
2017 Freund NT, Wang H, Scharf L, Nogueira L, Horwitz JA, Bar-On Y, Golijanin J, Sievers SA, Sok D, Cai H, Cesar Lorenzi JC, Halper-Stromberg A, Toth I, Piechocka-Trocha A, Gristick HB, et al. Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller. Science Translational Medicine. 9. PMID 28100831 DOI: 10.1126/Scitranslmed.Aal2144  0.337
2017 Wang H, Gristick HB, Scharf L, West AP, Galimidi RP, Seaman MS, Freund NT, Nussenzweig MC, Bjorkman PJ. Author response: Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies Elife. DOI: 10.7554/Elife.27389.032  0.343
2016 Scharf L, West AP, Sievers SA, Chen C, Jiang S, Gao H, Gray MD, McGuire AT, Scheid JF, Nussenzweig MC, Stamatatos L, Bjorkman PJ. Structural basis for germline antibody recognition of HIV-1 immunogens. Elife. 5. PMID 26997349 DOI: 10.7554/Elife.13783  0.44
2016 Scharf L, West AP, Sievers SA, Chen C, Jiang S, Gao H, Gray MD, McGuire AT, Scheid JF, Nussenzweig MC, Stamatatos L, Bjorkman PJ. Author response: Structural basis for germline antibody recognition of HIV-1 immunogens Elife. DOI: 10.7554/Elife.13783.028  0.352
2015 Ding S, Veillette M, Coutu M, Prévost J, Scharf L, Bjorkman PJ, Ferrari G, Robinson JE, Stürzel C, Hahn BH, Sauter D, Kirchhoff F, Lewis GK, Pazgier M, Finzi A. A Highly-Conserved Residue of the HIV-1-gp120 Inner Domain is Important for ADCC Responses Mediated by Anti-Cluster A Antibodies. Journal of Virology. PMID 26637462 DOI: 10.1128/Jvi.02779-15  0.365
2015 Freund NT, Horwitz JA, Nogueira L, Sievers SA, Scharf L, Scheid JF, Gazumyan A, Liu C, Velinzon K, Goldenthal A, Sanders RW, Moore JP, Bjorkman PJ, Seaman MS, Walker BD, et al. A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo. Plos Pathogens. 11: e1005238. PMID 26516768 DOI: 10.1371/Journal.Ppat.1005238  0.378
2015 Scharf L, Wang H, Gao H, Chen S, McDowall AW, Bjorkman PJ. Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env. Cell. 162: 1379-90. PMID 26359989 DOI: 10.1016/J.Cell.2015.08.035  0.397
2015 Dosenovic P, von Boehmer L, Escolano A, Jardine J, Freund NT, Gitlin AD, McGuire AT, Kulp DW, Oliveira T, Scharf L, Pietzsch J, Gray MD, Cupo A, van Gils MJ, Yao KH, et al. Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice. Cell. 161: 1505-15. PMID 26091035 DOI: 10.1016/J.Cell.2015.06.003  0.385
2014 Scharf L, Scheid JF, Lee JH, West AP, Chen C, Gao H, Gnanapragasam PN, Mares R, Seaman MS, Ward AB, Nussenzweig MC, Bjorkman PJ. Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike. Cell Reports. 7: 785-95. PMID 24767986 DOI: 10.1016/J.Celrep.2014.04.001  0.374
2014 West AP, Scharf L, Scheid JF, Klein F, Bjorkman PJ, Nussenzweig MC. Structural insights on the role of antibodies in HIV-1 vaccine and therapy. Cell. 156: 633-48. PMID 24529371 DOI: 10.1016/J.Cell.2014.01.052  0.343
2013 Luoma AM, Castro CD, Mayassi T, Bembinster LA, Bai L, Picard D, Anderson B, Scharf L, Kung JE, Sibener LV, Savage PB, Jabri B, Bendelac A, Adams EJ. Crystal structure of Vδ1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human γδ T cells. Immunity. 39: 1032-42. PMID 24239091 DOI: 10.1016/J.Immuni.2013.11.001  0.683
2013 Klein F, Mouquet H, Dosenovic P, Scheid JF, Scharf L, Nussenzweig MC. Antibodies in HIV-1 vaccine development and therapy. Science (New York, N.Y.). 341: 1199-204. PMID 24031012 DOI: 10.1126/Science.1241144  0.335
2013 Fox LM, Miksanek J, May NA, Scharf L, Lockridge JL, Veerapen N, Besra GS, Adams EJ, Hudson AW, Gumperz JE. Expression of CD1c enhances human invariant NKT cell activation by α-GalCer. Cancer Immunity. 13: 9. PMID 23885215  0.564
2013 West AP, Scharf L, Horwitz J, Klein F, Nussenzweig MC, Bjorkman PJ. Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues. Proceedings of the National Academy of Sciences of the United States of America. 110: 10598-603. PMID 23754383 DOI: 10.1073/Pnas.1309215110  0.354
2013 Li NS, Scharf L, Adams EJ, Piccirilli JA. Highly stereocontrolled total synthesis of β-D-mannosyl phosphomycoketide: a natural product from Mycobacterium tuberculosis. The Journal of Organic Chemistry. 78: 5970-86. PMID 23724960 DOI: 10.1021/Jo4006602  0.555
2013 Scharf L, West AP, Gao H, Lee T, Scheid JF, Nussenzweig MC, Bjorkman PJ, Diskin R. Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody. Proceedings of the National Academy of Sciences of the United States of America. 110: 6049-54. PMID 23524883 DOI: 10.1073/Pnas.1303682110  0.386
2013 Luoma AM, Castro CD, Mayassi T, Bembinster LA, Bai L, Picard D, Anderson B, Scharf L, Kung JE, Sibener LV, Savage PB, Jabri B, Bendelac A, Adams EJ. Crystal Structure of V delta 1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human gamma delta T Cells. Immunity. 39: 1032-1042. DOI: 10.2210/Pdb4Mng/Pdb  0.658
2012 Mouquet H, Scharf L, Euler Z, Liu Y, Eden C, Scheid JF, Halper-Stromberg A, Gnanapragasam PN, Spencer DI, Seaman MS, Schuitemaker H, Feizi T, Nussenzweig MC, Bjorkman PJ. Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies. Proceedings of the National Academy of Sciences of the United States of America. 109: E3268-77. PMID 23115339 DOI: 10.1073/Pnas.1217207109  0.388
2012 Sandstrom A, Scharf L, McRae G, Hawk AJ, Meredith SC, Adams EJ. γδ T cell receptors recognize the non-classical major histocompatibility complex (MHC) molecule T22 via conserved anchor residues in a MHC peptide-like fashion. The Journal of Biological Chemistry. 287: 6035-43. PMID 22215668 DOI: 10.1074/Jbc.M111.333153  0.599
2010 Scharf L, Li NS, Hawk AJ, Garzón D, Zhang T, Fox LM, Kazen AR, Shah S, Haddadian EJ, Gumperz JE, Saghatelian A, Faraldo-Gómez JD, Meredith SC, Piccirilli JA, Adams EJ. The 2.5 Ã… structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation. Immunity. 33: 853-62. PMID 21167756 DOI: 10.1016/J.Immuni.2010.11.026  0.624
2009 Fox LM, Cox DG, Lockridge JL, Wang X, Chen X, Scharf L, Trott DL, Ndonye RM, Veerapen N, Besra GS, Howell AR, Cook ME, Adams EJ, Hildebrand WH, Gumperz JE. Recognition of lyso-phospholipids by human natural killer T lymphocytes. Plos Biology. 7: e1000228. PMID 19859526 DOI: 10.1371/Journal.Pbio.1000228  0.637
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