| Year |
Citation |
Score |
| 2024 |
Eade L, Sullivan MP, Allison TM, Goldstone DC, Hartinger C. Not All Binding Sites Are Equal: Site Determination and Folding State Analysis of Gas-phase Protein-Metallodrug Adducts. Chemistry (Weinheim An Der Bergstrasse, Germany). e202400268. PMID 38472116 DOI: 10.1002/chem.202400268 |
0.649 |
|
| 2024 |
Long D, Eade L, Sullivan MP, Dost K, Meier-Menches SM, Goldstone DC, Hartinger CG, Wicker JS, Taškova K. AdductHunter: identifying protein-metal complex adducts in mass spectra. Journal of Cheminformatics. 16: 15. PMID 38321500 DOI: 10.1186/s13321-023-00797-7 |
0.635 |
|
| 2023 |
Łomzik M, Błauż A, Głodek M, Makal A, Tchoń D, Ayine-Tora DM, Hartinger C, Rychlik B, Plażuk D. Organometallic Ru, Os, Rh and Ir half-sandwich conjugates of ispinesib - impact of the organometallic group on the antimitotic activity. Dalton Transactions (Cambridge, England : 2003). PMID 37464882 DOI: 10.1039/d3dt01217d |
0.315 |
|
| 2023 |
Tremlett WDJ, Söhnel T, Crowley JD, Wright LJ, Hartinger CG. Ferrocene-Derived Palladium(II)-Based Metallosupramolecular Structures: Synthesis, Guest Interaction, and Stimulus-Responsiveness Studies. Inorganic Chemistry. PMID 36791401 DOI: 10.1021/acs.inorgchem.2c04399 |
0.336 |
|
| 2023 |
Sullivan MP, Adams M, Riisom M, Herbert CD, Tong KKH, Astin JW, Jamieson SMF, Hanif M, Goldstone DC, Hartinger CG. Platinum(terpyridine) complexes with N-heterocyclic carbene co-ligands: high antiproliferative activity and low toxicity . Dalton Transactions (Cambridge, England : 2003). PMID 36637059 DOI: 10.1039/d2dt02539f |
0.697 |
|
| 2022 |
Riaz Z, Lee BYT, Stjärnhage J, Movassaghi S, Söhnel T, Jamieson SMF, Shaheen MA, Hanif M, Hartinger CG. Anticancer Ru and Os complexes of N-(4-chlorophenyl)pyridine-2-carbothioamide: Substitution of the labile chlorido ligand with phosphines. Journal of Inorganic Biochemistry. 241: 112115. PMID 36731369 DOI: 10.1016/j.jinorgbio.2022.112115 |
0.399 |
|
| 2022 |
Lee BYT, Phillips AD, Hanif M, Söhnel T, Hartinger CG. Triazolyl- vs Pyridyl-Functionalized -Heterocyclic Carbene Complexes: Impact of the Pendant N-Donor Ligand on Intramolecular C-C Bond Formation. Acs Organic & Inorganic Au. 2: 511-524. PMID 36510612 DOI: 10.1021/acsorginorgau.2c00035 |
0.331 |
|
| 2022 |
Tong KKH, Riisom M, Leung E, Hanif M, Söhnel T, Jamieson SMF, Hartinger CG. Impact of Coordination Mode and Ferrocene Functionalization on the Anticancer Activity of N-Heterocyclic Carbene Half-Sandwich Complexes. Inorganic Chemistry. 61: 17226-17241. PMID 36240488 DOI: 10.1021/acs.inorgchem.2c02832 |
0.396 |
|
| 2022 |
Riisom M, Eade L, Tremlett WDJ, Hartinger CG. The aqueous stability and interactions of organoruthenium compounds with serum proteins, cell culture medium and human serum. Metallomics : Integrated Biometal Science. PMID 35751650 DOI: 10.1093/mtomcs/mfac043 |
0.38 |
|
| 2021 |
Green LPM, Steel TR, Riisom M, Hanif M, Söhnel T, Jamieson SMF, Wright LJ, Crowley JD, Hartinger CG. Synthetic Strategy Towards Heterodimetallic Half-Sandwich Complexes Based on a Symmetric Ditopic Ligand. Frontiers in Chemistry. 9: 786367. PMID 34926406 DOI: 10.3389/fchem.2021.786367 |
0.427 |
|
| 2021 |
Lee BYT, Sullivan MP, Yano E, Tong KKH, Hanif M, Kawakubo-Yasukochi T, Jamieson SMF, Soehnel T, Goldstone DC, Hartinger CG. Anthracenyl Functionalization of Half-Sandwich Carbene Complexes: Anticancer Activity and Reactions with Biomolecules. Inorganic Chemistry. PMID 34528438 DOI: 10.1021/acs.inorgchem.1c01675 |
0.698 |
|
| 2021 |
Tong K, Hanif M, Movassaghi S, Sullivan MP, Lovett J, Hummitzsch K, Soehnel T, Jamieson S, Bhargava S, Harris H, Hartinger C. Triazolyl-functionalized N-Heterocyclic Carbene Half-sandwich Compounds: Coordination Mode, Reactivity and in vitro Anticancer Activity. Chemmedchem. PMID 34196118 DOI: 10.1002/cmdc.202100311 |
0.706 |
|
| 2021 |
Sullivan MP, Cziferszky M, Tolbatov I, Truong D, Mercadante D, Re N, Gust R, Goldstone DC, Hartinger C. Probing the Paradigm of Promiscuity for N-Heterocyclic Carbene Complexes and their Protein Adduct Formation. Angewandte Chemie (International Ed. in English). PMID 34196088 DOI: 10.1002/anie.202106906 |
0.713 |
|
| 2021 |
Mirzadeh N, Reddy TS, Luwor R, Privér S, Reddy VG, Kumar JR, Stephens AN, Plebanski M, Hartinger C, Bhargava S. Dinuclear orthometallated gold(I)-gold(III) anti-cancer complexes with potent in vivo activity through a ROS-dependent mechanism. Metallomics : Integrated Biometal Science. PMID 34165566 DOI: 10.1093/mtomcs/mfab039 |
0.326 |
|
| 2021 |
Lee BYT, Phillips AD, Hanif M, Tong KKH, Söhnel T, Hartinger CG. Heptadentate, Octadentate, Or Even Nonadentate? Denticity in the Unexpected Formation of an All-Carbon Donor-Atom Ligand in Rh(Cp*)(Anthracenyl-NHC) Complexes. Inorganic Chemistry. PMID 34100283 DOI: 10.1021/acs.inorgchem.1c00711 |
0.322 |
|
| 2021 |
Yano E, Riisom M, Tong KKH, Hanif M, Leung E, Hartinger CG. Tracing the anticancer compound [Ru(η--cymene)(8-oxyquinolinato)Cl] in a biological environment by mass spectrometric methods. Analytical Methods : Advancing Methods and Applications. PMID 33683234 DOI: 10.1039/d0ay02311f |
0.342 |
|
| 2021 |
Arshad J, Tong KKH, Movassaghi S, Söhnel T, Jamieson SMF, Hanif M, Hartinger CG. Impact of the Metal Center and Leaving Group on the Anticancer Activity of Organometallic Complexes of Pyridine-2-carbothioamide. Molecules (Basel, Switzerland). 26. PMID 33562622 DOI: 10.3390/molecules26040833 |
0.392 |
|
| 2021 |
Shakil MS, Parveen S, Rana Z, Walsh F, Movassaghi S, Söhnel T, Azam M, Shaheen MA, Jamieson SMF, Hanif M, Rosengren RJ, Hartinger CG. High Antiproliferative Activity of Hydroxythiopyridones over Hydroxypyridones and Their Organoruthenium Complexes. Biomedicines. 9. PMID 33513800 DOI: 10.3390/biomedicines9020123 |
0.337 |
|
| 2021 |
Adams M, Sullivan MP, Tong KKH, Goldstone DC, Hanif M, Jamieson SMF, Hartinger CG. Mustards-Derived Terpyridine-Platinum Complexes as Anticancer Agents: DNA Alkylation vs Coordination. Inorganic Chemistry. PMID 33497565 DOI: 10.1021/acs.inorgchem.0c03317 |
0.711 |
|
| 2021 |
Małecka M, Skoczyńska A, Goodman DM, Hartinger CG, Budzisz E. Biological properties of ruthenium(II)/(III) complexes with flavonoids as ligands Coordination Chemistry Reviews. 436: 213849. DOI: 10.1016/J.CCR.2021.213849 |
0.318 |
|
| 2020 |
Daubit IM, Sullivan MP, John M, Goldstone DC, Hartinger CG, Metzler-Nolte N. A Combined Spectroscopic and Protein Crystallography Study Reveals Protein Interactions of Rh(NHC) Complexes at the Molecular Level. Inorganic Chemistry. PMID 33180473 DOI: 10.1021/acs.inorgchem.0c02438 |
0.704 |
|
| 2020 |
Łomzik M, Hanif M, Budniok A, Błauż A, Makal A, Tchoń DM, Leśniewska B, Tong KKH, Movassaghi S, Söhnel T, Jamieson SMF, Zafar A, Reynisson J, Rychlik B, Hartinger CG, et al. Metal-Dependent Cytotoxic and Kinesin Spindle Protein Inhibitory Activity of Ru, Os, Rh, and Ir Half-Sandwich Complexes of Ispinesib-Derived Ligands. Inorganic Chemistry. PMID 33003697 DOI: 10.1021/acs.inorgchem.0c00957 |
0.439 |
|
| 2020 |
Tong KKH, Hanif M, Lovett JH, Hummitzsch K, Harris HH, Söhnel T, Jamieson SMF, Hartinger CG. Thiourea-Derived Chelating Ligands and Their Organometallic Compounds: Investigations into Their Anticancer Activity. Molecules (Basel, Switzerland). 25. PMID 32796732 DOI: 10.3390/Molecules25163661 |
0.452 |
|
| 2020 |
Hanif M, Arshad J, Astin J, Rana Z, Zafar A, Movassaghi S, Leung E, Patel K, Soehnel T, Reynisson J, Sarojini V, Rosengren R, Jamieson S, Hartinger C. A Multitargeted Approach in the Discovery of an Organorhodium Anticancer Agent Based On Vorinostat as a Potent Histone Deacetylase Inhibitor. Angewandte Chemie (International Ed. in English). PMID 32431061 DOI: 10.1002/Anie.202005758 |
0.372 |
|
| 2020 |
Lisboa LS, Findlay JA, Wright LJ, Hartinger CG, Crowley JD. A low symmetry heterobimetallic [PdPtL4]4+ cage: assembly, guest binding and stimulus-induced switching. Angewandte Chemie (International Ed. in English). PMID 32220036 DOI: 10.1002/Anie.202003220 |
0.4 |
|
| 2020 |
Truong D, Sullivan MP, Tong KKH, Steel TR, Prause A, Lovett JH, Andersen JW, Jamieson SMF, Harris HH, Ott I, Weekley CM, Hummitzsch K, Söhnel T, Hanif M, Metzler-Nolte N, ... ... Hartinger CG, et al. Potent Inhibition of Thioredoxin Reductase by the Rh Derivatives of Anticancer M(arene/Cp*)(NHC)Cl Complexes. Inorganic Chemistry. PMID 32073260 DOI: 10.1021/Acs.Inorgchem.9B03640 |
0.726 |
|
| 2020 |
Mohabeer PK, Carr B, Hanif M, Hartinger C, Groutso T, Jelley RE, Söhnel T, Blackman AG. Synthesis, structure and fluxionality of Co(III) complexes containing chelated sulfate Polyhedron. 176: 114303. DOI: 10.1016/J.Poly.2019.114303 |
0.452 |
|
| 2019 |
Parveen S, Hanif M, Leung E, Tong KKH, Yang A, Astin J, De Zoysa GH, Steel TR, Goodman D, Movassaghi S, Söhnel T, Sarojini V, Jamieson SMF, Hartinger CG. Anticancer organorhodium and -iridium complexes with low toxicity in vivo but high potency in vitro: DNA damage, reactive oxygen species formation, and haemolytic activity. Chemical Communications (Cambridge, England). PMID 31498360 DOI: 10.1039/C9Cc03822A |
0.388 |
|
| 2019 |
Tremlett WDJ, Tong KKH, Steel TR, Movassaghi S, Hanif M, Jamieson SMF, Söhnel T, Hartinger CG. Hydroxyquinoline-derived anticancer organometallics: Introduction of amphiphilic PTA as an ancillary ligand increases their aqueous solubility. Journal of Inorganic Biochemistry. 199: 110768. PMID 31357065 DOI: 10.1016/J.Jinorgbio.2019.110768 |
0.498 |
|
| 2019 |
Sullivan MP, Morrow SJ, Goldstone DC, Hartinger CG. Gel Electrophoresis in Combination with Laser Ablation-Inductively Coupled Plasma Mass Spectrometry to Quantify the Interaction of Cisplatin with Human Serum Albumin. Electrophoresis. PMID 31087392 DOI: 10.1002/Elps.201900070 |
0.638 |
|
| 2019 |
Parveen S, Tong K, Rauf M, Kubanik M, Shaheen M, Soehnel T, Jamieson S, Hanif M, Hartinger C. Coordination Chemistry of Organoruthenium Compounds with Benzoylthiourea Ligands and their Biological Properties. Chemistry, An Asian Journal. PMID 30706633 DOI: 10.1002/Asia.201801798 |
0.487 |
|
| 2019 |
Sullivan MP, Nieuwoudt MK, Bowmaker GA, Lam NYS, Truong D, Goldstone DC, Hartinger CG. Correction: Unexpected arene ligand exchange results in the oxidation of an organoruthenium anticancer agent: the first X-ray structure of a protein-Ru(carbene) adduct. Chemical Communications (Cambridge, England). 55: 716. PMID 30600817 DOI: 10.1039/c8cc90551g |
0.635 |
|
| 2019 |
Ashraf A, Aman F, Movassaghi S, Zafar A, Kubanik M, Siddiqui WA, Reynisson J, Söhnel T, Jamieson SMF, Hanif M, Hartinger CG. Structural Modifications of the Antiinflammatory Oxicam Scaffold and Preparation of Anticancer Organometallic Compounds Organometallics. 38: 361-374. DOI: 10.1021/Acs.Organomet.8B00751 |
0.494 |
|
| 2019 |
Enyedy ÉA, Mészáros JP, Spengler G, Hanif M, Hartinger CG. Comparative solution studies and cytotoxicity of gallium(III) and iron(III) complexes of 3-hydroxy-2(1H)-pyridinones Polyhedron. 172: 141-147. DOI: 10.1016/J.Poly.2019.04.010 |
0.422 |
|
| 2019 |
Kumar S, Gallician G, Weidener D, Sullivan MP, Söhnel T, Hanif M, Hartinger CG. Design of organoruthenium complexes for nanoparticle functionalization Journal of Organometallic Chemistry. 891: 64-71. DOI: 10.1016/J.Jorganchem.2019.03.020 |
0.688 |
|
| 2018 |
Arshad J, Hanif M, Zafar A, Movassaghi S, Tong KKH, Reynisson J, Kubanik M, Waseem A, Söhnel T, Jamieson SMF, Hartinger CG. Organoruthenium and Organoosmium Complexes of 2-Pyridinecarbothioamides Functionalized with a Sulfonamide Motif: Synthesis, Cytotoxicity and Biomolecule Interactions. Chempluschem. 83: 612-619. PMID 31950635 DOI: 10.1002/Cplu.201800194 |
0.507 |
|
| 2018 |
Lam NYS, Truong D, Burmeister H, Babak MV, Holtkamp HU, Movassaghi S, Ayine-Tora DM, Zafar A, Kubanik M, Oehninger L, Söhnel T, Reynisson J, Jamieson SMF, Gaiddon C, Ott I, ... Hartinger CG, et al. From Catalysis to Cancer: Toward Structure-Activity Relationships for Benzimidazol-2-ylidene-Derived N-Heterocyclic-Carbene Complexes as Anticancer Agents. Inorganic Chemistry. PMID 30406647 DOI: 10.1021/Acs.Inorgchem.8B02634 |
0.534 |
|
| 2018 |
Ashraf A, Ejaz SA, Rahman SU, Siddiqui WA, Arshad MN, Lecka J, Sévigny J, Zayed MEM, Asiri AM, Iqbal J, Hartinger CG, Hanif M. Hybrid compounds from chalcone and 1,2-benzothiazine pharmacophores as selective inhibitors of alkaline phosphatase isozymes. European Journal of Medicinal Chemistry. 159: 282-291. PMID 30296687 DOI: 10.1016/J.Ejmech.2018.09.063 |
0.39 |
|
| 2018 |
Klose MHM, Schöberl A, Heffeter P, Berger W, Hartinger CG, Koellensperger G, Meier-Menches SM, Keppler BK. Serum-binding properties of isosteric ruthenium and osmium anticancer agents elucidated by SEC-ICP-MS. Monatshefte Fur Chemie. 149: 1719-1726. PMID 30237619 DOI: 10.1007/S00706-018-2280-1 |
0.414 |
|
| 2018 |
Nazarov AA, Mendoza-Ferri MG, Hanif M, Keppler BK, Dyson PJ, Hartinger CG. Understanding the interactions of diruthenium anticancer agents with amino acids. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 30046902 DOI: 10.1007/S00775-018-1597-X |
0.464 |
|
| 2018 |
Movassaghi S, Leung E, Hanif M, Lee BYT, Holtkamp HU, Tu JKY, Söhnel T, Jamieson SMF, Hartinger CG. A Bioactive l-Phenylalanine-Derived Arene in Multitargeted Organoruthenium Compounds: Impact on the Antiproliferative Activity and Mode of Action. Inorganic Chemistry. PMID 29949354 DOI: 10.1021/Acs.Inorgchem.8B01187 |
0.519 |
|
| 2018 |
Sullivan MP, Nieuwoudt MK, Bowmaker GA, Lam NYS, Truong D, Goldstone DC, Hartinger CG. Unexpected arene ligand exchange results in the oxidation of an organoruthenium anticancer agent: the first X-ray structure of a protein-Ru(carbene) adduct. Chemical Communications (Cambridge, England). PMID 29713703 DOI: 10.1039/C8Cc02433B |
0.691 |
|
| 2018 |
Holtkamp HU, Movassaghi S, Morrow SJ, Kubanik M, Hartinger CG. Metallomic study on the metabolism of RAPTA-C and cisplatin in cell culture medium and its impact on cell accumulation. Metallomics : Integrated Biometal Science. PMID 29484339 DOI: 10.1039/C8Mt00024G |
0.372 |
|
| 2018 |
Babak MV, Pfaffeneder-Kmen M, Meier-Menches SM, Legina MS, Theiner S, Licona C, Orvain C, Hejl M, Hanif M, Jakupec MA, Keppler BK, Gaiddon C, Hartinger CG. Rollover Cyclometalated Bipyridine Platinum Complexes as Potent Anticancer Agents: Impact of the Ancillary Ligands on the Mode of Action. Inorganic Chemistry. 57: 2851-2864. PMID 29442506 DOI: 10.1021/Acs.Inorgchem.7B03210 |
0.479 |
|
| 2018 |
Hanif M, Hartinger CG. Anticancer metallodrugs: where is the next cisplatin? Future Medicinal Chemistry. 10: 615-617. PMID 29411994 DOI: 10.4155/Fmc-2017-0317 |
0.374 |
|
| 2018 |
Giringer K, Holtkamp HU, Movassaghi S, Tremlett W, Lam NYS, Kubanik M, Hartinger CG. Analysis of ruthenium anticancer agents by MEEKC-UV and MEEKC-ICP-MS: impact of structural motifs on lipophilicity and biological activity. Electrophoresis. PMID 29400408 DOI: 10.1002/Elps.201700443 |
0.49 |
|
| 2018 |
Sullivan MP, Holtkamp HU, Hartinger CG. Antitumor Metallodrugs that Target Proteins. Metal Ions in Life Sciences. 18. PMID 29394032 DOI: 10.1515/9783110470734-019 |
0.682 |
|
| 2018 |
Movassaghi S, Hanif M, Holtkamp HU, Söhnel T, Jamieson SMF, Hartinger CG. Making organoruthenium complexes of 8-hydroxyquinolines more hydrophilic: impact of a novel l-phenylalanine-derived arene ligand on the biological activity. Dalton Transactions (Cambridge, England : 2003). 47: 2192-2201. PMID 29359219 DOI: 10.1039/C7Dt04451H |
0.499 |
|
| 2018 |
Kubanik M, Lam NYS, Holtkamp HU, Söhnel T, Anderson RF, Jamieson SMF, Hartinger CG. Quinoline-para-quinones and metals: coordination-assisted formation of quinoline-ortho-quinones. Chemical Communications (Cambridge, England). PMID 29322135 DOI: 10.1039/C7Cc09478G |
0.346 |
|
| 2018 |
Meier-Menches SM, Gerner C, Berger W, Hartinger CG, Keppler BK. Structure-activity relationships for ruthenium and osmium anticancer agents - towards clinical development. Chemical Society Reviews. 47: 909-928. PMID 29170783 DOI: 10.1039/C7Cs00332C |
0.351 |
|
| 2018 |
Movassaghi S, Singh S, Mansur A, Tong KKH, Hanif M, Holtkamp HU, Söhnel T, Jamieson SMF, Hartinger CG. Correction to “(Pyridin-2-yl)-NHC Organoruthenium Complexes: Antiproliferative Properties and Reactivity Toward Biomolecules” Organometallics. 37: 4172-4172. DOI: 10.1021/Acs.Organomet.8B00706 |
0.415 |
|
| 2018 |
Movassaghi S, Singh S, Mansur A, Tong KKH, Hanif M, Holtkamp HU, Söhnel T, Jamieson SMF, Hartinger CG. (Pyridin-2-yl)-NHC Organoruthenium Complexes: Antiproliferative Properties and Reactivity toward Biomolecules Organometallics. 37: 1575-1584. DOI: 10.1021/Acs.Organomet.8B00153 |
0.467 |
|
| 2017 |
Hanif M, Meier SM, Adhireksan Z, Henke H, Martic S, Movassaghi S, Labib M, Kandioller W, Jamieson SMF, Hejl M, Jakupec MA, Kraatz HB, Davey CA, Keppler BK, Hartinger CG. Functionalization of Ruthenium(II)(η -p-cymene)(3-hydroxy-2-pyridone) Complexes with (Thio)Morpholine: Synthesis and Bioanalytical Studies. Chempluschem. 82: 841-847. PMID 31961568 DOI: 10.1002/Cplu.201700050 |
0.498 |
|
| 2017 |
Plażuk D, Wieczorek A, Ciszewski WM, Kowalczyk K, Błauż A, Pawlędzio S, Makal A, Eurtivong C, Arabshahi HJ, Reynisson J, Hartinger CG, Rychlik B. Synthesis and in vitro Biological Evaluation of Ferrocenyl Side-Chain-Functionalized Paclitaxel Derivatives. Chemmedchem. 12: 1882-1892. PMID 28941201 DOI: 10.1002/Cmdc.201700576 |
0.376 |
|
| 2017 |
Arshad J, Hanif M, Movassaghi S, Kubanik M, Waseem A, Söhnel T, Jamieson SMF, Hartinger CG. Anticancer Ru(η(6)-p-cymene) complexes of 2-pyridinecarbothioamides: A structure-activity relationship study. Journal of Inorganic Biochemistry. PMID 28916262 DOI: 10.1016/J.Jinorgbio.2017.08.034 |
0.482 |
|
| 2017 |
Artner C, Holtkamp HU, Hartinger CG, Meier-Menches SM. Characterizing activation mechanisms and binding preferences of ruthenium metallo-prodrugs by a competitive binding assay. Journal of Inorganic Biochemistry. 177: 322-327. PMID 28739166 DOI: 10.1016/J.Jinorgbio.2017.07.010 |
0.425 |
|
| 2017 |
Artner C, Holtkamp HU, Kandioller W, Hartinger CG, Meier-Menches SM, Keppler BK. DNA or protein? Capillary zone electrophoresis-mass spectrometry rapidly elucidates metallodrug binding selectivity. Chemical Communications (Cambridge, England). 53: 8002-8005. PMID 28675406 DOI: 10.1039/C7Cc04582D |
0.359 |
|
| 2017 |
Meier SM, Kreutz D, Winter L, Klose MHM, Cseh K, Weiss T, Bileck A, Alte B, Mader JC, Jana S, Chatterjee A, Bhattacharyya A, Hejl M, Jakupec MA, Heffeter P, ... ... Hartinger CG, et al. An Organoruthenium Anticancer Agent Shows Unexpected Target Selectivity For Plectin. Angewandte Chemie (International Ed. in English). PMID 28547791 DOI: 10.1002/Anie.201702242 |
0.323 |
|
| 2017 |
Sullivan MP, Groessl M, Meier SM, Kingston RL, Goldstone DC, Hartinger CG. The metalation of hen egg white lysozyme impacts protein stability as shown by ion mobility mass spectrometry, differential scanning calorimetry, and X-ray crystallography. Chemical Communications (Cambridge, England). PMID 28361137 DOI: 10.1039/C6Cc10150J |
0.626 |
|
| 2017 |
Aman F, Hanif M, Kubanik M, Ashraf A, Söhnel T, Jamieson SM, Siddiqui WA, Hartinger CG. Anti-Inflammatory Oxicams as Multi-donor Ligand Systems: pH- and Solvent-Dependent Coordination Modes of Meloxicam and Piroxicam to Ru and Os. Chemistry (Weinheim An Der Bergstrasse, Germany). 23: 4893-4902. PMID 28198061 DOI: 10.1002/Chem.201700263 |
0.441 |
|
| 2017 |
Holtkamp HU, Morrow SJ, Kubanik M, Hartinger CG. Cobalt complexes as internal standards for capillary zone electrophoresis-mass spectrometry studies in biological inorganic chemistry. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 28044210 DOI: 10.1007/S00775-016-1426-Z |
0.428 |
|
| 2017 |
Holtkamp HU, Hartinger CG. Advanced metallomics methods in anticancer metallodrug mode of action studies Trends in Analytical Chemistry. 104: 110-117. DOI: 10.1016/J.Trac.2017.09.023 |
0.382 |
|
| 2017 |
Ashraf A, Hanif M, Kubanik M, Söhnel T, Jamieson SMF, Bhattacharyya A, Hartinger CG. Aspirin-inspired organometallic compounds: Structural characterization and cytotoxicity Journal of Organometallic Chemistry. 839: 31-37. DOI: 10.1016/J.Jorganchem.2017.01.016 |
0.509 |
|
| 2017 |
Muller CMA, Babak MV, Kubanik M, Hanif M, Jamieson SMF, Hartinger CG, Wright LJ. Reprint of: Pt(II) pyridinium amidate (PYA) complexes: Preparation and in vitro anticancer activity studies Inorganica Chimica Acta. 454: 247-253. DOI: 10.1016/J.Ica.2016.09.045 |
0.421 |
|
| 2017 |
Hanif M, Meier SM, Adhireksan Z, Henke H, Martic S, Movassaghi S, Labib M, Kandioller W, Jamieson SMF, Hejl M, Jakupec MA, Kraatz H, Davey CA, Keppler BK, Hartinger CG. Back Cover: Functionalization of Ruthenium(II)(η6
-p
-cymene)(3-hydroxy-2-pyridone) Complexes with (Thio)Morpholine: Synthesis and Bioanalytical Studies (ChemPlusChem 6/2017) Chempluschem. 82. DOI: 10.1002/Cplu.201700176 |
0.379 |
|
| 2016 |
Hanif M, Moon S, Sullivan MP, Movassaghi S, Kubanik M, Goldstone DC, Söhnel T, Jamieson SM, Hartinger CG. Anticancer activity of Ru- and Os(arene) compounds of a maleimide-functionalized bioactive pyridinecarbothioamide ligand. Journal of Inorganic Biochemistry. PMID 27470012 DOI: 10.1016/J.Jinorgbio.2016.06.025 |
0.744 |
|
| 2016 |
Wieczorek A, Błauż A, Żal A, Arabshahi HJ, Reynisson J, Hartinger CG, Rychlik B, Plażuk D. Ferrocenyl Paclitaxel and Docetaxel Derivatives: Impact of an Organometallic Moiety on the Mode of Action of Taxanes. Chemistry (Weinheim An Der Bergstrasse, Germany). 22: 11413-21. PMID 27376707 DOI: 10.1002/Chem.201601809 |
0.362 |
|
| 2016 |
Kubanik M, Kandioller W, Kim K, Anderson RF, Klapproth E, Jakupec MA, Roller A, Söhnel T, Keppler BK, Hartinger CG. Towards targeting anticancer drugs: ruthenium(ii)-arene complexes with biologically active naphthoquinone-derived ligand systems. Dalton Transactions (Cambridge, England : 2003). PMID 27214822 DOI: 10.1039/C6Dt01110A |
0.524 |
|
| 2016 |
Holtkamp H, Grabmann G, Hartinger CG. Electrophoretic separation techniques and their hyphenation to mass spectrometry in biological inorganic chemistry. Electrophoresis. 37: 959-72. PMID 26643265 DOI: 10.1002/Elps.201500502 |
0.348 |
|
| 2016 |
Muller CMA, Babak MV, Kubanik M, Hanif M, Jamieson SMF, Hartinger CG, Wright LJ. Pt(II) pyridinium amidate (PYA) complexes: Preparation and in vitro anticancer activity studies Inorganica Chimica Acta. 450: 124-130. DOI: 10.1016/J.Ica.2016.05.025 |
0.421 |
|
| 2016 |
Ashraf A, Siddiqui WA, Akbar J, Mustafa G, Krautscheid H, Ullah N, Mirza B, Sher F, Hanif M, Hartinger CG. Metal complexes of benzimidazole derived sulfonamide: Synthesis, molecular structures and antimicrobial activity Inorganica Chimica Acta. 443: 179-185. DOI: 10.1016/J.Ica.2015.12.031 |
0.472 |
|
| 2016 |
Murray BS, Babak MV, Hartinger CG, Dyson PJ. The development of RAPTA compounds for the treatment of tumors Coordination Chemistry Reviews. 306: 86-114. DOI: 10.1016/J.Ccr.2015.06.014 |
0.358 |
|
| 2016 |
Parveen S, Hanif M, Movassaghi S, Sullivan MP, Kubanik M, Shaheen MA, Söhnel T, Jamieson SMF, Hartinger CG. Cationic Ru(η6-p-cymene) Complexes of 3-Hydroxy-4-pyr(id)ones - Lipophilic Triphenylphosphine as Co-Ligand Is Key to Highly Stable and Cytotoxic Anticancer Agents European Journal of Inorganic Chemistry. 2017: 1721-1727. DOI: 10.1002/Ejic.201601163 |
0.726 |
|
| 2016 |
Ashraf A, Kubanik M, Aman F, Holtkamp H, Söhnel T, Jamieson SMF, Hanif M, Siddiqui WA, Hartinger CG. RuII(η6‐p‐cymene) Complexes of Bioactive 1,2‐Benzothiazines: Protein Binding vs. Antitumor Activity European Journal of Inorganic Chemistry. 2016: 1376-1382. DOI: 10.1002/Ejic.201501361 |
0.505 |
|
| 2016 |
Kurzwernhart A, Mokesch S, Klapproth E, Adib‐Ravazi MS, Jakupec MA, Hartinger CG, Kandioller W, Keppler BK. Flavonoid‐Based Organometallics with Different Metal Centers – Investigations of the Effects on Reactivity and Cytotoxicity European Journal of Inorganic Chemistry. 2016: 240-246. DOI: 10.1002/Ejic.201501020 |
0.485 |
|
| 2015 |
Babak MV, Meier SM, Huber KVM, Reynisson J, Legin AA, Jakupec MA, Roller A, Stukalov A, Gridling M, Bennett KL, Colinge J, Berger W, Dyson PJ, Superti-Furga G, Keppler BK, ... Hartinger CG, et al. Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action. Chemical Science. 6: 2449-2456. PMID 29308157 DOI: 10.1039/C4Sc03905J |
0.403 |
|
| 2015 |
Babak MV, Plażuk D, Meier SM, Arabshahi HJ, Reynisson J, Rychlik B, Błauż A, Szulc K, Hanif M, Strobl S, Roller A, Keppler BK, Hartinger CG. Half-sandwich ruthenium(II) biotin conjugates as biological vectors to cancer cells. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 5110-7. PMID 25676245 DOI: 10.1002/Chem.201403974 |
0.456 |
|
| 2015 |
Nazarov AA, Meier SM, Zava O, Nosova YN, Milaeva ER, Hartinger CG, Dyson PJ. Protein ruthenation and DNA alkylation: chlorambucil-functionalized RAPTA complexes and their anticancer activity. Dalton Transactions (Cambridge, England : 2003). 44: 3614-23. PMID 25407500 DOI: 10.1039/C4Dt02764G |
0.422 |
|
| 2015 |
Kubanik M, Tu JKY, Söhnel T, Hejl M, Jakupec MA, Kandioller W, Keppler BK, Hartinger CG. Expanding on the Structural Diversity of Flavone- Derived RutheniumII(ƞ6-arene) Anticancer Agents Metallodrugs. 1. DOI: 10.1515/MEDR-2015-0001 |
0.414 |
|
| 2015 |
Kubanik M, Holtkamp H, Söhnel T, Jamieson SMF, Hartinger CG. Impact of the Halogen Substitution Pattern on the Biological Activity of Organoruthenium 8-Hydroxyquinoline Anticancer Agents Organometallics. 34: 5658-5668. DOI: 10.1021/Acs.Organomet.5B00868 |
0.461 |
|
| 2015 |
Kandioller W, Kubanik M, Bytzek AK, Jakupec MA, Roller A, Keppler BK, Hartinger CG. The rearrangement of tosylated flavones to 1′-(alkylamino)aurones with primary amines Tetrahedron. 71: 8953-8959. DOI: 10.1016/J.Tet.2015.09.062 |
0.336 |
|
| 2015 |
Moon S, Hanif M, Kubanik M, Holtkamp H, Söhnel T, Jamieson SMF, Hartinger CG. Organoruthenium and Osmium Anticancer Complexes Bearing a Maleimide Functional Group: Reactivity to Cysteine, Stability, and Cytotoxicity Chempluschem. 80: 231-236. DOI: 10.1002/Cplu.201402390 |
0.49 |
|
| 2015 |
Hartinger C. Ligand Design in Medicinal Inorganic Chemistry. Edited by Tim Storr. Angewandte Chemie. 54: 2324-2324. DOI: 10.1002/Anie.201412260 |
0.352 |
|
| 2015 |
Hartinger C. Ligand Design in Medicinal Inorganic Chemistry. Herausgegeben von Tim Storr. Angewandte Chemie. 127: 2354-2354. DOI: 10.1002/Ange.201412260 |
0.353 |
|
| 2014 |
Hanif M, Babak MV, Hartinger CG. Development of anticancer agents: wizardry with osmium. Drug Discovery Today. 19: 1640-8. PMID 24955838 DOI: 10.1016/J.Drudis.2014.06.016 |
0.44 |
|
| 2014 |
Hanif M, Nawaz MA, Babak MV, Iqbal J, Roller A, Keppler BK, Hartinger CG. RutheniumII(η6-arene) complexes of thiourea derivatives: synthesis, characterization and urease inhibition. Molecules (Basel, Switzerland). 19: 8080-92. PMID 24936709 DOI: 10.3390/Molecules19068080 |
0.486 |
|
| 2014 |
Meier SM, Novak MS, Kandioller W, Jakupec MA, Roller A, Keppler BK, Hartinger CG. Aqueous chemistry and antiproliferative activity of a pyrone-based phosphoramidate Ru(arene) anticancer agent. Dalton Transactions (Cambridge, England : 2003). 43: 9851-5. PMID 24872129 DOI: 10.1039/C4Dt00569D |
0.365 |
|
| 2014 |
Egger AE, Theiner S, Kornauth C, Heffeter P, Berger W, Keppler BK, Hartinger CG. Quantitative bioimaging by LA-ICP-MS: a methodological study on the distribution of Pt and Ru in viscera originating from cisplatin- and KP1339-treated mice. Metallomics : Integrated Biometal Science. 6: 1616-25. PMID 24823867 DOI: 10.1039/C4Mt00072B |
0.318 |
|
| 2014 |
Meier SM, Babak MV, Keppler BK, Hartinger CG. Efficiently detecting metallodrug-protein adducts: ion trap versus time-of-flight mass analyzers. Chemmedchem. 9: 1351-5. PMID 24643974 DOI: 10.1002/Cmdc.201400020 |
0.4 |
|
| 2014 |
Dömötör O, Aicher S, Schmidlehner M, Novak MS, Roller A, Jakupec MA, Kandioller W, Hartinger CG, Keppler BK, Enyedy ÉA. Antitumor pentamethylcyclopentadienyl rhodium complexes of maltol and allomaltol: synthesis, solution speciation and bioactivity. Journal of Inorganic Biochemistry. 134: 57-65. PMID 24556426 DOI: 10.1016/J.Jinorgbio.2014.01.020 |
0.462 |
|
| 2014 |
Aman F, Hanif M, Siddiqui W, Ashraf A, Filak L, Reynisson J, Soehnel T, Jamieson S, Hartinger C. Anticancer Ruthenium(η 6 - p -cymene) Complexes of Nonsteroidal Anti-inflammatory Drug Derivatives Organometallics. 33: 5546-5553. DOI: 10.1021/Om500825H |
0.436 |
|
| 2014 |
Sija E, Hartinger CG, Keppler BK, Kiss T, Enyedy EA. Solution equilibrium studies of anticancer ruthenium(II)-η6- p-cymene complexes of pyridinecarboxylic acids Polyhedron. 67: 51-58. DOI: 10.1016/J.Poly.2013.08.057 |
0.37 |
|
| 2014 |
Nazarov AA, Hartinger CG, Dyson PJ. Opening the lid on piano-stool complexes: An account of ruthenium(II)–arene complexes with medicinal applications Journal of Organometallic Chemistry. 751: 251-260. DOI: 10.1016/J.Jorganchem.2013.09.016 |
0.392 |
|
| 2013 |
Hanif M, Meier SM, Nazarov AA, Risse J, Legin A, Casini A, Jakupec MA, Keppler BK, Hartinger CG. Influence of the π-coordinated arene on the anticancer activity of ruthenium(II) carbohydrate organometallic complexes. Frontiers in Chemistry. 1: 27. PMID 24790955 DOI: 10.3389/Fchem.2013.00027 |
0.501 |
|
| 2013 |
Enyedy EA, Sija E, Jakusch T, Hartinger CG, Kandioller W, Keppler BK, Kiss T. Solution equilibria of anticancer ruthenium(II)-(η(6)-p-cymene)-hydroxy(thio)pyr(id)one complexes: impact of sulfur vs. oxygen donor systems on the speciation and bioactivity. Journal of Inorganic Biochemistry. 127: 161-8. PMID 23721887 DOI: 10.1016/J.Jinorgbio.2013.05.002 |
0.477 |
|
| 2013 |
Meier SM, Novak M, Kandioller W, Jakupec MA, Arion VB, Metzler-Nolte N, Keppler BK, Hartinger CG. Identification of the structural determinants for anticancer activity of a ruthenium arene peptide conjugate Chemistry - a European Journal. 19: 9297-9307. PMID 23712572 DOI: 10.1002/Chem.201300889 |
0.389 |
|
| 2013 |
Hartinger CG, Groessl M, Meier SM, Casini A, Dyson PJ. Application of mass spectrometric techniques to delineate the modes-of-action of anticancer metallodrugs. Chemical Society Reviews. 42: 6186-99. PMID 23660626 DOI: 10.1039/C3Cs35532B |
0.39 |
|
| 2013 |
Grabmann G, Keppler BK, Hartinger CG. A systematic capillary electrophoresis study on the effect of the buffer composition on the reactivity of the anticancer drug cisplatin to the DNA model 2'-deoxyguanosine 5'-monophosphate (dGMP). Analytical and Bioanalytical Chemistry. 405: 6417-24. PMID 23620371 DOI: 10.1007/S00216-013-6937-7 |
0.398 |
|
| 2013 |
Kandioller W, Balsano E, Meier SM, Jungwirth U, Göschl S, Roller A, Jakupec MA, Berger W, Keppler BK, Hartinger CG. Organometallic anticancer complexes of lapachol: metal centre-dependent formation of reactive oxygen species and correlation with cytotoxicity. Chemical Communications (Cambridge, England). 49: 3348-50. PMID 23505633 DOI: 10.1039/C3Cc40432C |
0.425 |
|
| 2013 |
Valiahdi SM, Egger AE, Miklos W, Jungwirth U, Meelich K, Nock P, Berger W, Hartinger CG, Galanski M, Jakupec MA, Keppler BK. Influence of extracellular pH on the cytotoxicity, cellular accumulation, and DNA interaction of novel pH-sensitive 2-aminoalcoholatoplatinum(II) complexes. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 18: 249-60. PMID 23354303 DOI: 10.1007/S00775-012-0970-4 |
0.369 |
|
| 2013 |
Babak MV, Meier SM, Legin AA, Adib Razavi MS, Roller A, Jakupec MA, Keppler BK, Hartinger CG. Am(m)ines make the difference: organoruthenium am(m)ine complexes and their chemistry in anticancer drug development. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 4308-18. PMID 23341078 DOI: 10.1002/Chem.201202657 |
0.528 |
|
| 2013 |
De Luca A, Hartinger CG, Dyson PJ, Lo Bello M, Casini A. A new target for gold(I) compounds: glutathione-S-transferase inhibition by auranofin. Journal of Inorganic Biochemistry. 119: 38-42. PMID 23183361 DOI: 10.1016/J.Jinorgbio.2012.08.006 |
0.409 |
|
| 2013 |
Kurzwernhart A, Kandioller W, Enyedy ÉA, Novak M, Jakupec MA, Keppler BK, Hartinger CG. 3-Hydroxyflavones vs. 3-hydroxyquinolinones: structure-activity relationships and stability studies on Ru(II)(arene) anticancer complexes with biologically active ligands. Dalton Transactions (Cambridge, England : 2003). 42: 6193-202. PMID 23168616 DOI: 10.1039/C2Dt32206D |
0.506 |
|
| 2013 |
Dömötör O, Hartinger CG, Bytzek AK, Kiss T, Keppler BK, Enyedy EA. Characterization of the binding sites of the anticancer ruthenium(III) complexes KP1019 and KP1339 on human serum albumin via competition studies. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 18: 9-17. PMID 23076343 DOI: 10.1007/S00775-012-0944-6 |
0.382 |
|
| 2013 |
Groessl M, Hartinger CG. Anticancer metallodrug research analytically painting the "omics" picture--current developments and future trends. Analytical and Bioanalytical Chemistry. 405: 1791-808. PMID 23070042 DOI: 10.1007/S00216-012-6450-4 |
0.361 |
|
| 2013 |
Meier SM, Hanif M, Adhireksan Z, Pichler V, Novak M, Jirkovsky E, Jakupec MA, Arion VB, Davey CA, Keppler BK, Hartinger CG. Novel metal(ii) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents Chemical Science. 4: 1837. DOI: 10.1039/C3Sc22294B |
0.493 |
|
| 2013 |
Enyedy EA, Bognár GM, Kiss T, Hanif M, Hartinger CG. Solution equilibrium studies on anticancer ruthenium(II)-η6- p-cymene complexes of 3-hydroxy-2(1H)-pyridones Journal of Organometallic Chemistry. 734: 38-44. DOI: 10.1016/J.Jorganchem.2012.10.042 |
0.443 |
|
| 2013 |
Schwarz MB, Kurzwernhart A, Roller A, Kandioller W, Keppler BK, Hartinger CG. Rhodium(Cp*) Compounds with Flavone‐derived Ligand Systems: Synthesis and Characterization Zeitschrift FüR Anorganische Und Allgemeine Chemie. 639: 1648-1654. DOI: 10.1002/Zaac.201300145 |
0.499 |
|
| 2012 |
Kurzwernhart A, Kandioller W, Bächler S, Bartel C, Martic S, Buczkowska M, Mühlgassner G, Jakupec MA, Kraatz HB, Bednarski PJ, Arion VB, Marko D, Keppler BK, Hartinger CG. Structure-activity relationships of targeted RuII(η6-p-cymene) anticancer complexes with flavonol-derived ligands. Journal of Medicinal Chemistry. 55: 10512-22. PMID 23134291 DOI: 10.1021/Jm301376A |
0.506 |
|
| 2012 |
Enyedy ÉA, Dömötör O, Varga E, Kiss T, Trondl R, Hartinger CG, Keppler BK. Comparative solution equilibrium studies of anticancer gallium(III) complexes of 8-hydroxyquinoline and hydroxy(thio)pyrone ligands. Journal of Inorganic Biochemistry. 117: 189-97. PMID 23089600 DOI: 10.1016/J.Jinorgbio.2012.08.005 |
0.413 |
|
| 2012 |
Henke H, Kandioller W, Hanif M, Keppler BK, Hartinger CG. Organometallic ruthenium and osmium compounds of pyridin-2- and -4-ones as potential anticancer agents. Chemistry & Biodiversity. 9: 1718-27. PMID 22976964 DOI: 10.1002/Cbdv.201200005 |
0.482 |
|
| 2012 |
Grabmann G, Meier SM, Scaffidi-Domianello YY, Galanski M, Keppler BK, Hartinger CG. Capillary zone electrophoresis and capillary zone electrophoresis-electrospray ionization mass spectrometry studies on the behavior of anticancer cis- and trans-[dihalidobis(2-propanone oxime)platinum(II)] complexes in aqueous solutions. Journal of Chromatography. A. 1267: 156-61. PMID 22897861 DOI: 10.1016/J.Chroma.2012.07.062 |
0.408 |
|
| 2012 |
Kurzwernhart A, Kandioller W, Bartel C, Bächler S, Trondl R, Mühlgassner G, Jakupec MA, Arion VB, Marko D, Keppler BK, Hartinger CG. Targeting the DNA-topoisomerase complex in a double-strike approach with a topoisomerase inhibiting moiety and covalent DNA binder. Chemical Communications (Cambridge, England). 48: 4839-41. PMID 22498692 DOI: 10.1039/C2Cc31040F |
0.378 |
|
| 2012 |
Bytzek AK, Hartinger CG. Capillary electrophoretic methods in the development of metal-based therapeutics and diagnostics: new methodology and applications. Electrophoresis. 33: 622-34. PMID 22451055 DOI: 10.1002/Elps.201100402 |
0.307 |
|
| 2012 |
Meier SM, Hanif M, Kandioller W, Keppler BK, Hartinger CG. Biomolecule binding vs. anticancer activity: reactions of Ru(arene)[(thio)pyr-(id)one] compounds with amino acids and proteins. Journal of Inorganic Biochemistry. 108: 91-5. PMID 22420927 DOI: 10.1016/J.Jinorgbio.2011.08.011 |
0.466 |
|
| 2012 |
Nazarov AA, Risse J, Ang WH, Schmitt F, Zava O, Ruggi A, Groessl M, Scopelitti R, Juillerat-Jeanneret L, Hartinger CG, Dyson PJ. Anthracene-tethered ruthenium(II) arene complexes as tools to visualize the cellular localization of putative organometallic anticancer compounds. Inorganic Chemistry. 51: 3633-9. PMID 22394115 DOI: 10.1021/Ic202530J |
0.43 |
|
| 2012 |
Jungwirth U, Xanthos DN, Gojo J, Bytzek AK, Körner W, Heffeter P, Abramkin SA, Jakupec MA, Hartinger CG, Windberger U, Galanski M, Keppler BK, Berger W. Anticancer activity of methyl-substituted oxaliplatin analogs. Molecular Pharmacology. 81: 719-28. PMID 22331606 DOI: 10.1124/Mol.111.077321 |
0.332 |
|
| 2012 |
Bartel C, Bytzek AK, Scaffidi-Domianello YY, Grabmann G, Jakupec MA, Hartinger CG, Galanski M, Keppler BK. Cellular accumulation and DNA interaction studies of cytotoxic trans-platinum anticancer compounds. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 17: 465-74. PMID 22227950 DOI: 10.1007/S00775-011-0869-5 |
0.446 |
|
| 2012 |
Meier SM, Tsybin YO, Dyson PJ, Keppler BK, Hartinger CG. Fragmentation methods on the balance: unambiguous top-down mass spectrometric characterization of oxaliplatin-ubiquitin binding sites. Analytical and Bioanalytical Chemistry. 402: 2655-62. PMID 22065348 DOI: 10.1007/S00216-011-5523-0 |
0.334 |
|
| 2012 |
Hanif M, Nazarov AA, Legin A, Groessl M, Arion VB, Jakupec MA, Tsybin YO, Dyson PJ, Keppler BK, Hartinger CG. Maleimide-functionalised organoruthenium anticancer agents and their binding to thiol-containing biomolecules. Chemical Communications (Cambridge, England). 48: 1475-7. PMID 22003496 DOI: 10.1039/C1Cc14713G |
0.406 |
|
| 2012 |
Hudej R, Kljun J, Kandioller W, Repnik U, Turk B, Hartinger CG, Keppler BK, Miklavčič D, Turel I. Synthesis and Biological Evaluation of the Thionated Antibacterial Agent Nalidixic Acid and Its Organoruthenium(II) Complex Organometallics. 31: 5867-5874. DOI: 10.1021/Om300424W |
0.463 |
|
| 2012 |
Hanif M, Nazarov AA, Hartinger CG. Synthesis of [RuII(η6-p-cymene)(PPh3)(L)Cl]PF6 complexes with carbohydrate-derived phosphites, imidazole or indazole co-ligands Inorganica Chimica Acta. 380: 211-215. DOI: 10.1016/J.Ica.2011.10.007 |
0.433 |
|
| 2011 |
Hartinger CG, Phillips AD, Nazarov AA. Polynuclear ruthenium, osmium and gold complexes. the quest for innovative anticancer chemotherapeutics Current Topics in Medicinal Chemistry. 11: 2688-2702. PMID 22039871 DOI: 10.2174/156802611798040769 |
0.444 |
|
| 2011 |
Nazarov A, Hartinger C. Editorial [Hot Topic: Metal Containing Complexes with Anticancer Properties (Guest Editors: A. Nazarov & C. Hartinger)] Current Topics in Medicinal Chemistry. 11: 2601-2601. PMID 22039865 DOI: 10.2174/156802611798040750 |
0.377 |
|
| 2011 |
Bytzek AK, Boeck K, Hermann G, Hann S, Keppler BK, Hartinger CG, Koellensperger G. LC- and CZE-ICP-MS approaches for the in vivo analysis of the anticancer drug candidate sodium trans-[tetrachloridobis(1H-indazole)ruthenate(III)] (KP1339) in mouse plasma. Metallomics : Integrated Biometal Science. 3: 1049-55. PMID 21935553 DOI: 10.1039/C1Mt00055A |
0.361 |
|
| 2011 |
Enyedy EA, Horváth L, Hetényi A, Tuccinardi T, Hartinger CG, Keppler BK, Kiss T. Interactions of the carrier ligands of antidiabetic metal complexes with human serum albumin: a combined spectroscopic and separation approach with molecular modeling studies. Bioorganic & Medicinal Chemistry. 19: 4202-10. PMID 21696966 DOI: 10.1016/J.Bmc.2011.05.063 |
0.398 |
|
| 2011 |
Kljun J, Bytzek AK, Kandioller W, Bartel C, Jakupec MA, Hartinger CG, Keppler BK, Turel I. Physicochemical Studies and Anticancer Potency of Ruthenium η-p-Cymene Complexes Containing Antibacterial Quinolones. Organometallics. 30: 2506-2512. PMID 21552495 DOI: 10.1021/Om101180C |
0.476 |
|
| 2011 |
Wu B, Ong MS, Groessl M, Adhireksan Z, Hartinger CG, Dyson PJ, Davey CA. A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 3562-6. PMID 21344528 DOI: 10.1002/Chem.201100298 |
0.344 |
|
| 2011 |
Jungwirth U, Kowol CR, Keppler BK, Hartinger CG, Berger W, Heffeter P. Anticancer activity of metal complexes: involvement of redox processes. Antioxidants & Redox Signaling. 15: 1085-127. PMID 21275772 DOI: 10.1089/Ars.2010.3663 |
0.397 |
|
| 2011 |
Hanif M, Meier SM, Kandioller W, Bytzek A, Hejl M, Hartinger CG, Nazarov AA, Arion VB, Jakupec MA, Dyson PJ, Keppler BK. From hydrolytically labile to hydrolytically stable Ru(II)-arene anticancer complexes with carbohydrate-derived co-ligands. Journal of Inorganic Biochemistry. 105: 224-31. PMID 21194622 DOI: 10.1016/J.Jinorgbio.2010.10.004 |
0.49 |
|
| 2011 |
Reithofer MR, Bytzek AK, Valiahdi SM, Kowol CR, Groessl M, Hartinger CG, Jakupec MA, Galanski M, Keppler BK. Tuning of lipophilicity and cytotoxic potency by structural variation of anticancer platinum(IV) complexes. Journal of Inorganic Biochemistry. 105: 46-51. PMID 21134601 DOI: 10.1016/J.Jinorgbio.2010.09.006 |
0.444 |
|
| 2011 |
Kandioller W, Kurzwernhart A, Hanif M, Meier SM, Henke H, Keppler BK, Hartinger CG. Pyrone derivatives and metals: From natural products to metal-based drugs Journal of Organometallic Chemistry. 696: 999-1010. DOI: 10.1016/J.Jorganchem.2010.11.010 |
0.341 |
|
| 2010 |
Görmen M, Pigeon P, Top S, Hillard EA, Huché M, Hartinger CG, de Montigny F, Plamont MA, Vessières A, Jaouen G. Synthesis, cytotoxicity, and COMPARE analysis of ferrocene and [3]ferrocenophane tetrasubstituted olefin derivatives against human cancer cells. Chemmedchem. 5: 2039-50. PMID 20949584 DOI: 10.1002/Cmdc.201000286 |
0.379 |
|
| 2010 |
Abramkin SA, Jungwirth U, Valiahdi SM, Dworak C, Habala L, Meelich K, Berger W, Jakupec MA, Hartinger CG, Nazarov AA, Galanski M, Keppler BK. {(1R,2R,4R)-4-methyl-1,2-cyclohexanediamine}oxalatoplatinum(II): a novel enantiomerically pure oxaliplatin derivative showing improved anticancer activity in vivo. Journal of Medicinal Chemistry. 53: 7356-64. PMID 20886814 DOI: 10.1021/Jm100953C |
0.329 |
|
| 2010 |
Hartinger CG. Trapping unstable benzoquinone analogues by coordination to a [(η(5)-C(5)Me(5))Ir] fragment and the anticancer activity of the resulting complexes. Angewandte Chemie (International Ed. in English). 49: 8304-5. PMID 20803595 DOI: 10.1002/Anie.201003565 |
0.397 |
|
| 2010 |
Hanif M, Henke H, Meier SM, Martic S, Labib M, Kandioller W, Jakupec MA, Arion VB, Kraatz HB, Keppler BK, Hartinger CG. Is the reactivity of M(II)-arene complexes of 3-hydroxy-2(1H)-pyridones to biomolecules the anticancer activity determining parameter? Inorganic Chemistry. 49: 7953-63. PMID 20704358 DOI: 10.1021/Ic1009785 |
0.523 |
|
| 2010 |
Hanif M, Nazarov AA, Hartinger CG, Kandioller W, Jakupec MA, Arion VB, Dyson PJ, Keppler BK. Osmium(II)--versus ruthenium(II)--arene carbohydrate-based anticancer compounds: similarities and differences. Dalton Transactions (Cambridge, England : 2003). 39: 7345-52. PMID 20601976 DOI: 10.1039/C003085F |
0.465 |
|
| 2010 |
Fei Z, Zhu DR, Yang X, Meng L, Lu Q, Ang WH, Scopelliti R, Hartinger CG, Dyson PJ. An internal fluorescent probe based on anthracene to evaluate cation-anion interactions in imidazolium salts. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 6473-81. PMID 20455221 DOI: 10.1002/Chem.201000253 |
0.314 |
|
| 2010 |
Egger AE, Hartinger CG, Renfrew AK, Dyson PJ. Metabolization of [Ru(eta(6)-C (6)H (5)CF (3))(pta)Cl (2)]: a cytotoxic RAPTA-type complex with a strongly electron withdrawing arene ligand. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 15: 919-27. PMID 20364440 DOI: 10.1007/S00775-010-0654-X |
0.459 |
|
| 2010 |
Bytzek AK, Reithofer MR, Galanski M, Groessl M, Keppler BK, Hartinger CG. The first example of MEEKC-ICP-MS coupling and its application for the analysis of anticancer platinum complexes. Electrophoresis. 31: 1144-50. PMID 20349510 DOI: 10.1002/Elps.200900522 |
0.379 |
|
| 2010 |
Groessl M, Tsybin YO, Hartinger CG, Keppler BK, Dyson PJ. Ruthenium versus platinum: interactions of anticancer metallodrugs with duplex oligonucleotides characterised by electrospray ionisation mass spectrometry. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 15: 677-88. PMID 20213306 DOI: 10.1007/S00775-010-0635-0 |
0.348 |
|
| 2010 |
Hanif M, Schaaf P, Kandioller W, Hejl M, Jakupec MA, Roller A, Keppler BK, Hartinger CG. Influence of the Arene Ligand and the Leaving Group on the Anticancer Activity of (Thio)maltol Ruthenium(II)–(η6-Arene) Complexes Australian Journal of Chemistry. 63: 1521-1528. DOI: 10.1071/Ch10232 |
0.516 |
|
| 2010 |
Kasser JH, Kandioller W, Hartinger CG, Nazarov AA, Arion VB, Dyson PJ, Keppler BK. Mannich products of kojic acid and N-heterocycles and their Ru(II)-arene complexes: Synthesis, characterization and stability Journal of Organometallic Chemistry. 695: 875-881. DOI: 10.1016/J.Jorganchem.2010.01.007 |
0.48 |
|
| 2010 |
Renfrew AK, Egger AE, Scopelliti R, Hartinger CG, Dyson PJ. Synthesis and characterisation of the water soluble bis-phosphine complex [Ru(η6-cymene)(PPh2(o-C6H4O)-κ2-P,O)(pta)]+ and an investigation of its cytotoxic effects Comptes Rendus Chimie. 13: 1144-1150. DOI: 10.1016/J.Crci.2010.03.014 |
0.453 |
|
| 2010 |
Casini A, Hartinger CG, Nazarov AA, Dyson PJ. Organometallic Antitumour Agents with Alternative Modes of Action Topics in Organometallic Chemistry. 32: 57-80. DOI: 10.1007/978-3-642-13185-1_3 |
0.348 |
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| 2009 |
Egger AE, Rappel C, Jakupec MA, Hartinger CG, Heffeter P, Keppler BK. Development of an experimental protocol for uptake studies of metal compounds in adherent tumor cells. Journal of Analytical Atomic Spectrometry. 24: 51-61. PMID 22723721 DOI: 10.1039/B810481F |
0.364 |
|
| 2009 |
Bytzek AK, Enyedy EA, Kiss T, Keppler BK, Hartinger CG. Biodistribution of anti-diabetic Zn(II) complexes in human serum and in vitro protein-binding studies by means of CZE-ICP-MS. Electrophoresis. 30: 4075-82. PMID 19960475 DOI: 10.1002/Elps.200900212 |
0.396 |
|
| 2009 |
Kandioller W, Hartinger CG, Nazarov AA, Bartel C, Skocic M, Jakupec MA, Arion VB, Keppler BK. Maltol-derived ruthenium-cymene complexes with tumor inhibiting properties: the impact of ligand-metal bond stability on anticancer activity in vitro. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 12283-91. PMID 19821465 DOI: 10.1002/Chem.200901939 |
0.508 |
|
| 2009 |
Groessl M, Bytzek A, Hartinger CG. The serum protein binding of pharmacologically active gallium(III) compounds assessed by hyphenated CE-MS techniques. Electrophoresis. 30: 2720-7. PMID 19621374 DOI: 10.1002/Elps.200800745 |
0.359 |
|
| 2009 |
Kasser J, Nazarov AA, Hartinger CG, Wdziekonski B, Dani C, Kuznetsov ML, Arion VB, Keppler BK. A one step/one pot synthesis of N,N-bis(phosphonomethyl)amino acids and their effects on adipogenic and osteogenic differentiation of human mesenchymal stem cells. Bioorganic & Medicinal Chemistry. 17: 3388-93. PMID 19369079 DOI: 10.1016/J.Bmc.2009.03.039 |
0.3 |
|
| 2009 |
Mendoza-Ferri MG, Hartinger CG, Mendoza MA, Groessl M, Egger AE, Eichinger RE, Mangrum JB, Farrell NP, Maruszak M, Bednarski PJ, Klein F, Jakupec MA, Nazarov AA, Severin K, Keppler BK. Transferring the concept of multinuclearity to ruthenium complexes for improvement of anticancer activity. Journal of Medicinal Chemistry. 52: 916-25. PMID 19170599 DOI: 10.1021/Jm8013234 |
0.469 |
|
| 2009 |
Hartinger CG, Dyson PJ. Bioorganometallic chemistry--from teaching paradigms to medicinal applications. Chemical Society Reviews. 38: 391-401. PMID 19169456 DOI: 10.1039/B707077M |
0.386 |
|
| 2009 |
Nováková O, Nazarov AA, Hartinger CG, Keppler BK, Brabec V. DNA interactions of dinuclear RuII arene antitumor complexes in cell-free media Biochemical Pharmacology. 77: 364-374. PMID 19014908 DOI: 10.1016/J.Bcp.2008.10.021 |
0.457 |
|
| 2009 |
Mendoza-Ferri MG, Hartinger CG, Nazarov AA, Eichinger RE, Jakupec MA, Severin K, Keppler BK. Influence of the arene ligand, the number and type of metal centers, and the leaving group on the in vitro antitumor activity of polynuclear organometallic compounds Organometallics. 28: 6260-6265. DOI: 10.1021/Om900715J |
0.497 |
|
| 2009 |
Kandioller W, Hartinger CG, Nazarov AA, Kuznetsov ML, John RO, Bartel C, Jakupec MA, Arion VB, Keppler BK. From Pyrone to Thiopyrone Ligands−Rendering Maltol-Derived Ruthenium(II)−Arene Complexes That Are Anticancer Active in Vitro Organometallics. 28: 4249-4251. DOI: 10.1021/Om900483T |
0.389 |
|
| 2009 |
Renfrew AK, Phillips AD, Egger AE, Hartinger CG, Bosquain SS, Nazarov AA, Keppler BK, Gonsalvi L, Peruzzini M, Dyson PJ. Influence of Structural Variation on the Anticancer Activity of RAPTA-Type Complexes: ptn versus pta Organometallics. 28: 1165-1172. DOI: 10.1021/Om800899E |
0.452 |
|
| 2009 |
Kandioller W, Hartinger CG, Nazarov AA, Kasser J, John R, Jakupec MA, Arion VB, Dyson PJ, Keppler BK. Tuning the anticancer activity of maltol-derived ruthenium complexes by derivatization of the 3-hydroxy-4-pyrone moiety Journal of Organometallic Chemistry. 694: 922-929. DOI: 10.1016/J.Jorganchem.2008.10.016 |
0.461 |
|
| 2009 |
Biba F, Groessl M, Egger A, Roller A, Hartinger CG, Keppler BK. New Insights into the Chemistry of the Antineoplastic Lanthanum Complex Tris(1,10-phenanthroline)tris(thiocyanato-κN)lanthanum(III) (KP772) and Its Interaction with Biomolecules European Journal of Inorganic Chemistry. 2009: 4282-4287. DOI: 10.1002/Ejic.200900038 |
0.47 |
|
| 2008 |
Ashraf SM, Kandioller W, Mendoza-Ferri M, Nazarov AA, Hartinger CG, Keppler BK. The Hydration of Chloroacetonitriles Catalyzed by Mono- and Dinuclear Ru II - and Os II -Arene Complexes Chemistry & Biodiversity. 5: 2060-2066. PMID 18972538 DOI: 10.1002/Cbdv.200890188 |
0.427 |
|
| 2008 |
Hartinger CG, Jakupec MA, Zorbas-Seifried S, Groessl M, Egger A, Berger W, Zorbas H, Dyson PJ, Keppler BK. KP1019, a new redox-active anticancer agent--preclinical development and results of a clinical phase I study in tumor patients. Chemistry & Biodiversity. 5: 2140-55. PMID 18972504 DOI: 10.1002/Cbdv.200890195 |
0.332 |
|
| 2008 |
Egger AE, Hartinger CG, Ben Hamidane H, Tsybin YO, Keppler BK, Dyson PJ. High resolution mass spectrometry for studying the interactions of cisplatin with oligonucleotides. Inorganic Chemistry. 47: 10626-33. PMID 18947179 DOI: 10.1021/Ic801371R |
0.342 |
|
| 2008 |
Hartinger CG, Nazarov AA, Ashraf SM, Dyson PJ, Keppler BK. Carbohydrate-metal complexes and their potential as anticancer agents. Current Medicinal Chemistry. 15: 2574-91. PMID 18855680 DOI: 10.2174/092986708785908978 |
0.487 |
|
| 2008 |
Hartinger CG, Casini A, Duhot C, Tsybin YO, Messori L, Dyson PJ. Stability of an organometallic ruthenium-ubiquitin adduct in the presence of glutathione: relevance to antitumour activity. Journal of Inorganic Biochemistry. 102: 2136-41. PMID 18834634 DOI: 10.1016/J.Jinorgbio.2008.08.002 |
0.435 |
|
| 2008 |
Casini A, Gabbiani C, Sorrentino F, Rigobello MP, Bindoli A, Geldbach TJ, Marrone A, Re N, Hartinger CG, Dyson PJ, Messori L. Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium(II)-arene compounds. Journal of Medicinal Chemistry. 51: 6773-81. PMID 18834187 DOI: 10.1021/Jm8006678 |
0.389 |
|
| 2008 |
Ashraf SM, Berger I, Nazarov AA, Hartinger CG, Koroteev MP, Nifant'ev EE, Keppler BK. Phosphite-derivatized ruthenium-carbohydrate complexes in the catalytic hydration of nitriles. short communication. Chemistry & Biodiversity. 5: 1640-1644. PMID 18729099 DOI: 10.1002/Cbdv.200890151 |
0.428 |
|
| 2008 |
Groessl M, Hartinger CG, Połeć-Pawlak K, Jarosz M, Dyson PJ, Keppler BK. Elucidation of the interactions of an anticancer ruthenium complex in clinical trials with biomolecules utilizing capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry. Short communication. Chemistry & Biodiversity. 5: 1609-14. PMID 18729095 DOI: 10.1002/Cbdv.200890148 |
0.453 |
|
| 2008 |
Berger I, Hanif M, Nazarov AA, Hartinger CG, John RO, Kuznetsov ML, Groessl M, Schmitt F, Zava O, Biba F, Arion VB, Galanski M, Jakupec MA, Juillerat-Jeanneret L, Dyson PJ, et al. In vitro anticancer activity and biologically relevant metabolization of organometallic ruthenium complexes with carbohydrate-based ligands. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 9046-57. PMID 18688905 DOI: 10.1002/Chem.200801032 |
0.461 |
|
| 2008 |
Chatterjee S, Kundu S, Bhattacharyya A, Hartinger CG, Dyson PJ. The ruthenium(II)-arene compound RAPTA-C induces apoptosis in EAC cells through mitochondrial and p53-JNK pathways. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 13: 1149-55. PMID 18597125 DOI: 10.1007/S00775-008-0400-9 |
0.301 |
|
| 2008 |
Scolaro C, Hartinger CG, Allardyce CS, Keppler BK, Dyson PJ. Hydrolysis study of the bifunctional antitumour compound RAPTA-C, [Ru(eta6-p-cymene)Cl2(pta)]. Journal of Inorganic Biochemistry. 102: 1743-8. PMID 18582946 DOI: 10.1016/J.Jinorgbio.2008.05.004 |
0.37 |
|
| 2008 |
Groessl M, Hartinger CG, Polec-Pawlak K, Jarosz M, Keppler BK. Capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry: A novel approach for the analysis of anticancer metallodrugs in human serum and plasma Electrophoresis. 29: 2224-2232. PMID 18512673 DOI: 10.1002/Elps.200780790 |
0.393 |
|
| 2008 |
Heffeter P, Jungwirth U, Jakupec M, Hartinger C, Galanski M, Elbling L, Micksche M, Keppler B, Berger W. Resistance against novel anticancer metal compounds: Differences and similarities Drug Resistance Updates. 11: 1-16. PMID 18394950 DOI: 10.1016/J.Drup.2008.02.002 |
0.351 |
|
| 2008 |
Casini A, Hartinger C, Gabbiani C, Mini E, Dyson PJ, Keppler BK, Messori L. Gold(III) compounds as anticancer agents: relevance of gold-protein interactions for their mechanism of action. Journal of Inorganic Biochemistry. 102: 564-75. PMID 18177942 DOI: 10.1016/J.Jinorgbio.2007.11.003 |
0.424 |
|
| 2008 |
Jakupec MA, Galanski M, Arion VB, Hartinger CG, Keppler BK. Antitumour metal compounds: more than theme and variations. Dalton Transactions. 183-94. PMID 18097483 DOI: 10.1039/B712656P |
0.464 |
|
| 2008 |
Dorcier A, Hartinger CG, Scopelliti R, Fish RH, Keppler BK, Dyson PJ. Studies on the reactivity of organometallic Ru-, Rh- and Os-pta complexes with DNA model compounds Journal of Inorganic Biochemistry. 102: 1066-1076. PMID 18086499 DOI: 10.1016/J.Jinorgbio.2007.10.016 |
0.465 |
|
| 2008 |
Mendoza-Ferri MG, Hartinger CG, Eichinger RE, Stolyarova N, Severin K, Jakupec MA, Nazarov AA, Keppler BK. Influence of the spacer length on the in vitro anticancer activity of dinuclear ruthenium arene compounds Organometallics. 27: 2405-2407. DOI: 10.1021/Om800207T |
0.407 |
|
| 2008 |
Habala L, Dworak C, Nazarov AA, Hartinger CG, Abramkin SA, Arion VB, Lindner W, Galanski M, Keppler BK. Methyl-substituted trans-1,2-cyclohexanediamines as new ligands for oxaliplatin-type complexes Tetrahedron. 64: 137-146. DOI: 10.1016/J.Tet.2007.10.069 |
0.379 |
|
| 2008 |
Chaplin AB, Béni Z, Hartinger CG, Hamidane HB, Phillips AD, Scopelliti R, Dyson PJ. Linked metal-cluster systems: Isolation and characterisation of {anti-[(p-cymene)RuCl]-μ-[κ 2-P,P′κ 1-P′-(PPh2CH2)3CMe]-[AuPt 3(CO)3(PCy3)3]}(PF6) 2 Journal of Cluster Science. 19: 295-309. DOI: 10.1007/S10876-007-0175-0 |
0.371 |
|
| 2008 |
Mendoza-Ferri MG, Hartinger CG, Nazarov AA, Kandioller W, Severin K, Keppler BK. Modifying the structure of dinuclear ruthenium complexes with antitumor activity Applied Organometallic Chemistry. 22: 326-332. DOI: 10.1002/Aoc.1394 |
0.496 |
|
| 2007 |
Groessl M, Hartinger CG, Dyson PJ, Keppler BK. CZE-ICP-MS as a tool for studying the hydrolysis of ruthenium anticancer drug candidates and their reactivity towards the DNA model compound dGMP. Journal of Inorganic Biochemistry. 102: 1060-5. PMID 18222004 DOI: 10.1016/J.Jinorgbio.2007.11.018 |
0.415 |
|
| 2007 |
Hartinger CG, Tsybin YO, Fuchser J, Dyson PJ. Characterization of platinum anticancer drug protein-binding sites using a top-down mass spectrometric approach. Inorganic Chemistry. 47: 17-9. PMID 18067289 DOI: 10.1021/Ic702236M |
0.366 |
|
| 2007 |
Scolaro C, Chaplin AB, Hartinger CG, Bergamo A, Cocchietto M, Keppler BK, Sava G, Dyson PJ. Tuning the hydrophobicity of ruthenium(II)-arene (RAPTA) drugs to modify uptake, biomolecular interactions and efficacy. Dalton Transactions (Cambridge, England : 2003). 5065-72. PMID 17992291 DOI: 10.1039/B705449A |
0.398 |
|
| 2007 |
Hartinger CG, Keppler BK. CE in anticancer metallodrug research--an update. Electrophoresis. 28: 3436-3446. PMID 17847132 DOI: 10.1002/Elps.200700114 |
0.413 |
|
| 2007 |
Timerbaev AR, Foteeva LS, Rudnev AV, Abramski JK, Połeć‐Pawlak K, Hartinger CG, Jarosz M, Keppler BK. Probing the stability of serum protein-ruthenium(III) drug adducts in the presence of extracellular reductants using CE. Electrophoresis. 28: 2235-2240. PMID 17557359 DOI: 10.1002/Elps.200600707 |
0.393 |
|
| 2007 |
Groessl M, Reisner E, Hartinger CG, Eichinger R, Semenova O, Timerbaev AR, Jakupec MA, Arion VB, Keppler BK. Structure-activity relationships for NAMI-A-type complexes (HL)[trans-RuCl4L(S-dmso)ruthenate(III)] (L = imidazole, indazole, 1,2,4-triazole, 4-amino-1,2,4-triazole, and 1-methyl-1,2,4-triazole): aquation, redox properties, protein binding, and antiproliferative activity. Journal of Medicinal Chemistry. 50: 2185-93. PMID 17402720 DOI: 10.1021/Jm061081Y |
0.5 |
|
| 2007 |
Berger I, Nazarov AA, Hartinger CG, Groessl M, Valiahdi S, Jakupec MA, Keppler BK. A glucose derivative as natural alternative to the cyclohexane-1,2-diamine ligand in the anticancer drug oxaliplatin? Chemmedchem. 2: 505-514. PMID 17340670 DOI: 10.1002/Cmdc.200600279 |
0.5 |
|
| 2007 |
Aleksenko SS, Hartinger CG, Semenova O, Meelich K, Timerbaev AR, Keppler BK. Characterization of interactions between human serum albumin and tumor-inhibiting amino alcohol platinum(II) complexes using capillary electrophoresis. Journal of Chromatography A. 1155: 218-221. PMID 17240384 DOI: 10.1016/J.Chroma.2007.01.017 |
0.429 |
|
| 2007 |
Zorbas-Seifried S, Jakupec MA, Kukushkin NV, Groessl M, Hartinger CG, Semenova O, Zorbas H, Kukushkin VY, Keppler BK. Reversion of structure-activity relationships of antitumor platinum complexes by acetoxime but not hydroxylamine ligands. Molecular Pharmacology. 71: 357-65. PMID 17050805 DOI: 10.1124/Mol.106.030726 |
0.416 |
|
| 2007 |
Hartinger CG, Ang WH, Casini A, Messori L, Keppler BK, Dyson PJ. Mass spectrometric analysis of ubiquitin–platinum interactions of leading anticancer drugs: MALDI versus ESI Journal of Analytical Atomic Spectrometry. 22: 960-967. DOI: 10.1039/B703350H |
0.387 |
|
| 2007 |
Berger I, Nazarov AA, Hartinger CG, Groessl M, Valiahdi S, Jakupec MA, Keppler BK. Cover Picture: A glucose derivative as natural alternative to the cyclohexane‐1,2‐diamine ligand in the anticancer drug oxaliplatin? (ChemMedChem 4/2007) Chemmedchem. 2: 385-385. DOI: 10.1002/Cmdc.200790008 |
0.335 |
|
| 2006 |
Zorbas-Seifried S, Hartinger CG, Meelich K, Galanski M, Keppler BK, Zorbas H. DNA interactions of pH-sensitive, antitumor bis(aminoalcohol) dichloroplatinum(II) complexes Biochemistry. 45: 14817-14825. PMID 17144675 DOI: 10.1021/Bi061063I |
0.345 |
|
| 2006 |
Hartinger CG, Zorbas-Seifried S, Jakupec MA, Kynast B, Zorbas H, Keppler BK. From bench to bedside – preclinical and early clinical development of the anticancer agent indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019 or FFC14A) Journal of Inorganic Biochemistry. 100: 891-904. PMID 16603249 DOI: 10.1016/J.Jinorgbio.2006.02.013 |
0.34 |
|
| 2006 |
Schluga P, Hartinger CG, Egger A, Reisner E, Galanski M, Jakupec MA, Keppler BK. Redox behavior of tumor-inhibiting ruthenium(III) complexes and effects of physiological reductants on their binding to GMP. Dalton Transactions (Cambridge, England : 2003). 1796-802. PMID 16568190 DOI: 10.1039/B511792E |
0.415 |
|
| 2006 |
Polec‐Pawlak K, Abramski JK, Semenova O, Hartinger CG, Timerbaev AR, Keppler BK, Jarosz M. Platinum group metallodrug-protein binding studies by capillary electrophoresis - inductively coupled plasma-mass spectrometry: a further insight into the reactivity of a novel antitumor ruthenium(III) complex toward human serum proteins. Electrophoresis. 27: 1128-1135. PMID 16440400 DOI: 10.1002/Elps.200500694 |
0.397 |
|
| 2006 |
Timerbaev AR, Hartinger CG, Keppler BK. Metallodrug research and analysis using capillary electrophoresis Trends in Analytical Chemistry. 25: 868-875. DOI: 10.1016/J.Trac.2006.04.009 |
0.315 |
|
| 2006 |
Hartinger CG, Ferri-Mendoza MG, Nazarov AA, Keppler BK. Electrospray ionization mass spectrometric study on the coordination behavior of dacarbazine towards transition metal ions Polyhedron. 25: 1971-1978. DOI: 10.1016/J.Poly.2005.12.022 |
0.467 |
|
| 2005 |
Schluga P, Hartinger CG, Galanski M, Meelich K, Timerbaev AR, Keppler BK. Tumour-inhibiting platinum(II) complexes with aminoalcohol ligands : biologically important transformations studied by micellar electrokinetic chromatography, nuclear magnetic resonance spectroscopy and mass spectrometry Analyst. 130: 1383-1389. PMID 16172663 DOI: 10.1039/B506490B |
0.425 |
|
| 2005 |
Timerbaev AR, Rudnev AV, Semenova O, Hartinger CG, Keppler BK. Comparative binding of antitumor indazolium [trans-tetrachlorobis(1H-indazole)ruthenate(III)] to serum transport proteins assayed by capillary zone electrophoresis. Analytical Biochemistry. 341: 326-333. PMID 15907879 DOI: 10.1016/J.Ab.2005.03.020 |
0.396 |
|
| 2005 |
Jakupec MA, Reisner E, Eichinger A, Pongratz M, Arion VB, Galanski M, Hartinger CG, Keppler BK. Redox-active antineoplastic ruthenium complexes with indazole: correlation of in vitro potency and reduction potential. Journal of Medicinal Chemistry. 48: 2831-7. PMID 15828821 DOI: 10.1021/Jm0490742 |
0.438 |
|
| 2005 |
Rudnev AV, Aleksenko SS, Semenova O, Hartinger CG, Timerbaev AR, Keppler BK. Determination of binding constants and stoichiometries for platinum anticancer drugs and serum transport proteins by capillary electrophoresis using the Hummel‐Dreyer method Ieee Journal of Solid-State Circuits. 28: 121-127. PMID 15754818 DOI: 10.1002/Jssc.200401930 |
0.342 |
|
| 2005 |
Sulyok M, Hann S, Hartinger CG, Keppler BK, Stingeder G, Koellensperger G. Two dimensional separation schemes for investigation of the interaction of an anticancer ruthenium(III) compound with plasma proteins Journal of Analytical Atomic Spectrometry. 20: 856-863. DOI: 10.1039/B508060F |
0.362 |
|
| 2005 |
Nazarov AA, Koroteev MP, Hartinger CG, Keppler BK, Nifant’ev EE. On the Coordination Properties of New Bicyclophosphite-Carbohydrates Monatshefte Fur Chemie. 136: 137-146. DOI: 10.1007/S00706-004-0238-Y |
0.384 |
|
| 2005 |
Hartinger CG, Nazarov AA, Arion VB, Giester G, Kuznetsov ML, Galanski M, Keppler BK. 1,1'‐Bis(oxazolin‐2‐yl)ferrocenes: An Investigation of Their Complexation Behavior toward [Pd(η3‐allyl)Cl]2 European Journal of Inorganic Chemistry. 2005: 1589-1600. DOI: 10.1002/Ejic.200400737 |
0.366 |
|
| 2004 |
Warnke U, Rappel C, Meier H, Kloft C, Galanski M, Hartinger CG, Keppler BK, Jaehde U. Analysis of platinum adducts with DNA nucleotides and nucleosides by capillary electrophoresis coupled to ESI-MS: indications of guanosine 5'-monophosphate O6-N7 chelation. Chembiochem : a European Journal of Chemical Biology. 5: 1543-9. PMID 15515088 DOI: 10.1002/Cbic.200400015 |
0.341 |
|
| 2004 |
Timerbaev AR, Aleksenko SS, Polec-Pawlak K, Ruzik R, Semenova O, Hartinger CG, Oszwaldowski S, Galanski M, Jarosz M, Keppler BK. Platinum metallodrug-protein binding studies by capillary electrophoresis-inductively coupled plasma-mass spectrometry: characterization of interactions between Pt(II) complexes and human serum albumin. Electrophoresis. 25: 1988-1995. PMID 15237398 DOI: 10.1002/Elps.200305984 |
0.445 |
|
| 2004 |
Pongratz M, Schluga P, Jakupec MA, Arion VB, Hartinger CG, Allmaier G, Keppler BK. Transferrin binding and transferrin-mediated cellular uptake of the ruthenium coordination compound KP1019, studied by means of AAS, ESI-MS and CD spectroscopy Journal of Analytical Atomic Spectrometry. 19: 46-51. DOI: 10.1039/B309160K |
0.383 |
|
| 2003 |
Hartinger CG, Schluga P, Galanski M, Baumgartner C, Timerbaev AR, Keppler BK. Tumor‐inhibiting platinum(II) complexes with aminoalcohol ligands: Comparison of the mode of action by capillary electrophoresis and electrospray ionization‐mass spectrometry Electrophoresis. 24: 2038-2044. PMID 12858373 DOI: 10.1002/Elps.200305463 |
0.399 |
|
| 2003 |
Hartinger CG, Timerbaev AR, Keppler BK. Capillary electrophoresis in anti-cancer metallodrug research: advances and future challenges. Electrophoresis. 24: 2023-2037. PMID 12858372 DOI: 10.1002/Elps.200305452 |
0.358 |
|
| 2003 |
Hartinger CG, Nazarov AA, Chevchenko V, Arion VB, Galanski M, Keppler BK. Synthesis, crystal structures, and electrospray ionisation mass spectrometry investigations of ether- and thioether-substituted ferrocenes Dalton Transactions. 3098-3102. DOI: 10.1039/B304115H |
0.378 |
|
| 2003 |
Arion VB, Nazarov AA, Hartinger CG, Giester G, Keppler BK. Crystallographic report: Crystal structure of 1-bromo-1'-[(2S)-N-(1-hydroxy-3-methylbutane-2-yl)]-ferroceneamide Applied Organometallic Chemistry. 17: 723-724. DOI: 10.1002/Aoc.501 |
0.306 |
|
| 2002 |
Nazarov AA, Hartinger CG, Arion VB, Giester G, Keppler BK. Synthesis of ferrocenylglucose phosphonite and bisphosphinite: Pd(II) and Pt(II) complexes, Pd-catalyzed allylic alkylation Tetrahedron. 58: 8489-8492. DOI: 10.1016/S0040-4020(02)01027-X |
0.349 |
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