Robert A. Durham - Publications

Affiliations: 
Pfizer, Inc., San Diego, CA, United States 
Area:
Alzheimer's, drug discovery

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Wood KM, McCush F, Conboy JJ, Durham R, Tate B, Bednar MM, Landen JW, Geoghegan KF, Bales KR. IP/MS analysis of human CSF Aβ following a single dose of the C-terminal anti-Aβ antibody ponezumab (PF-04360365) to Alzheimer patients Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1015  0.39
2009 Wang EQ, Wentland J, Rajadhyaksha M, Durham RA, Freeman GB. P3-273: Pharmacokinetic and pharmacodynamic evaluation of PF-04360365, a humanized monoclonal anti-amyloid antibody, in young and aged cynomolgus monkeys Alzheimer's & Dementia. 5: P423-P423. DOI: 10.1016/J.Jalz.2009.04.944  0.314
2008 Conboy JJ, Wood KG, Lame ME, Durham RA, Geoghegan KF. Modification of amyloid-beta(1-40) by a protease inhibitor creates risk of error in mass spectrometric quantitation of amyloid-beta(1-42). Analytical Biochemistry. 382: 147-9. PMID 18706385 DOI: 10.1016/J.Ab.2008.07.033  0.469
2005 Beach TG, Walker DG, Potter PE, Sue LI, Scott S, Layne KJ, Newell AJ, Rauschkolb PK, Poston ME, Webster SD, Durham RA, Emmerling MR, Sawada K, Honer WG, Fisher A, et al. Cortical cholinergic deafferentation induces aβ deposition toward a physiological animal model of alzheimer's disease Molecular Neurosurgery With Targeted Toxins. 143-180. DOI: 10.1007/978-1-59259-896-0_7  0.393
2004 Sunderland T, Mirza N, Putnam KT, Linker G, Bhupali D, Durham R, Soares H, Kimmel L, Friedman D, Bergeson J, Csako G, Levy JA, Bartko JJ, Cohen RM. Cerebrospinal fluid beta-amyloid1-42 and tau in control subjects at risk for Alzheimer's disease: the effect of APOE epsilon4 allele. Biological Psychiatry. 56: 670-6. PMID 15522251 DOI: 10.1016/j.biopsych.2004.07.021  0.408
2004 Cataldo AM, Petanceska S, Terio NB, Peterhoff CM, Durham R, Mercken M, Mehta PD, Buxbaum J, Haroutunian V, Nixon RA. Abeta localization in abnormal endosomes: association with earliest Abeta elevations in AD and Down syndrome. Neurobiology of Aging. 25: 1263-72. PMID 15465622 DOI: 10.1016/J.Neurobiolaging.2004.02.027  0.563
2003 Beach TG, Walker DG, Sue LI, Scott S, Layne KJ, Newell AJ, Potter PE, Durham RA, Emmerling MR, Webster SD. Immunotoxin Lesion of the Cholinergic Nucleus Basalis Causes Aβ Deposition: Towards a Physiologic Animal Model of Alzheimers Disease Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents. 3: 57-75. DOI: 10.2174/1568013033358635  0.462
2002 Walker LC, Bian F, Callahan MJ, Lipinski WJ, Durham RA, LeVine H. Modeling Alzheimer's disease and other proteopathies in vivo: is seeding the key? Amino Acids. 23: 87-93. PMID 12373522 DOI: 10.1007/S00726-001-0113-7  0.734
2002 Walker LC, Callahan MJ, Bian F, Durham RA, Roher AE, Lipinski WJ. Exogenous induction of cerebral beta-amyloidosis in betaAPP-transgenic mice. Peptides. 23: 1241-7. PMID 12128081 DOI: 10.1016/S0196-9781(02)00059-1  0.736
2001 Gyure KA, Durham R, Stewart WF, Smialek JE, Troncoso JC. Intraneuronal abeta-amyloid precedes development of amyloid plaques in Down syndrome. Archives of Pathology & Laboratory Medicine. 125: 489-92. PMID 11260621 DOI: 10.1043/0003-9985(2001)125<0489:Iaapdo>2.0.Co;2  0.463
2001 Callahan MJ, Lipinski WJ, Bian F, Durham RA, Pack A, Walker LC. Augmented senile plaque load in aged female beta-amyloid precursor protein-transgenic mice. The American Journal of Pathology. 158: 1173-7. PMID 11238065 DOI: 10.1016/S0002-9440(10)64064-3  0.707
2000 Roher AE, Kuo YM, Potter PE, Emmerling MR, Durham RA, Walker DG, Sue LI, Honer WG, Beach TG. Cortical cholinergic denervation elicits vascular A beta deposition. Annals of the New York Academy of Sciences. 903: 366-73. PMID 10818527 DOI: 10.1111/J.1749-6632.2000.Tb06388.X  0.485
2000 Kane MD, Lipinski WJ, Callahan MJ, Bian F, Durham RA, Schwarz RD, Roher AE, Walker LC. Evidence for seeding of beta -amyloid by intracerebral infusion of Alzheimer brain extracts in beta -amyloid precursor protein-transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3606-11. PMID 10804202  0.756
2000 Beach TG, Potter PE, Kuo YM, Emmerling MR, Durham RA, Webster SD, Walker DG, Sue LI, Scott S, Layne KJ, Roher AE. Cholinergic deafferentation of the rabbit cortex: a new animal model of Abeta deposition. Neuroscience Letters. 283: 9-12. PMID 10729621 DOI: 10.1016/S0304-3940(00)00916-2  0.559
2000 Kane MD, Lipinski WJ, Callahan MJ, Bian F, Durham RA, Schwarz RD, Roher AE, Walker LC. Evidence for Seeding of β-Amyloid by Intracerebral Infusion of Alzheimer Brain Extracts in β-Amyloid Precursor Protein-Transgenic Mice The Journal of Neuroscience. 20: 3606-3611. DOI: 10.1523/Jneurosci.20-10-03606.2000  0.736
2000 Durham RA, Emmerling MR, Roher AE, Davis MD, Walker LC. Measurement of Aβ40 and Aβ42 using microdialysis coupled to a sensitive sandwich ELISA Neurobiology of Aging. 21: 89. DOI: 10.1016/S0197-4580(00)82626-3  0.566
2000 Roher AE, Potter PE, Kuo Y, Emmerling MR, Durham RA, Webster SD, Walker DG, Beach TG. Selective deafferentation of the rabbit cortex: A new animal model of Alzheimer's disease Neurobiology of Aging. 21: 85. DOI: 10.1016/S0197-4580(00)82606-8  0.354
2000 Cataldo AM, Nixon RA, Troncoso JC, Durham RA, Buxbaum JD, Epstein C, Carlson E, Peterhoff CM. Endocytic alterations in human preclinical AD and a trisomic mouse model of down syndrome: Implications for β-amyloidogenesis Neurobiology of Aging. 21: 65. DOI: 10.1016/S0197-4580(00)82515-4  0.41
2000 Walker LC, Lipinski WJ, Callahan MJ, Bian F, Durham RA, Schwartz RD, Roher AE, Kane MD. Seeding of β-amyloidosis in βAPP-transgenic mice by the intracerebral injection of Alzheimer brain extract Neurobiology of Aging. 21: 126. DOI: 10.1016/S0197-4580(00)82366-0  0.686
1999 Walker LC, Durham RA. Cerebrovascular amyloidosis: experimental analysis in vitro and in vivo. Histology and Histopathology. 14: 827-37. PMID 10425553  0.639
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