| Year |
Citation |
Score |
| 2024 |
Mummey HM, Elison W, Korgaonkar K, Elgamal RM, Kudtarkar P, Griffin E, Benaglio P, Miller M, Jha A, Manning Fox JE, McCarthy MI, Preissl S, Gloyn AL, MacDonald PE, Gaulton KJ. Single cell multiome profiling of pancreatic islets reveals physiological changes in cell type-specific regulation associated with diabetes risk. Biorxiv : the Preprint Server For Biology. PMID 39149326 DOI: 10.1101/2024.08.03.606460 |
0.363 |
|
| 2024 |
McGrail C, Sears TJ, Kudtarkar P, Carter H, Gaulton K. Genetic association and machine learning improves discovery and prediction of type 1 diabetes. Medrxiv : the Preprint Server For Health Sciences. PMID 39132494 DOI: 10.1101/2024.07.31.24311310 |
0.351 |
|
| 2024 |
Smith K, Deutsch AJ, McGrail C, Kim H, Hsu S, Huerta-Chagoya A, Mandla R, Schroeder PH, Westerman KE, Szczerbinski L, Majarian TD, Kaur V, Williamson A, Zaitlen N, Claussnitzer M, ... ... Gaulton KJ, et al. Multi-ancestry polygenic mechanisms of type 2 diabetes. Nature Medicine. PMID 38443691 DOI: 10.1038/s41591-024-02865-3 |
0.305 |
|
| 2023 |
McGrail C, Chiou J, Elgamal R, Luckett AM, Oram RA, Benaglio P, Gaulton KJ. Genetic discovery and risk prediction for type 1 diabetes in individuals without high-risk HLA-DR3/DR4 haplotypes. Medrxiv : the Preprint Server For Health Sciences. PMID 37986756 DOI: 10.1101/2023.11.11.23298405 |
0.348 |
|
| 2023 |
Smith K, Deutsch AJ, McGrail C, Kim H, Hsu S, Mandla R, Schroeder PH, Westerman KE, Szczerbinski L, Majarian TD, Kaur V, Williamson A, Claussnitzer M, Florez JC, Manning AK, ... ... Gaulton KJ, et al. Multi-ancestry Polygenic Mechanisms of Type 2 Diabetes Elucidate Disease Processes and Clinical Heterogeneity. Research Square. PMID 37886436 DOI: 10.21203/rs.3.rs-3399145/v1 |
0.319 |
|
| 2023 |
Smith K, Deutsch AJ, McGrail C, Kim H, Hsu S, Mandla R, Schroeder PH, Westerman KE, Szczerbinski L, Majarian TD, Kaur V, Williamson A, Claussnitzer M, Florez JC, Manning AK, ... ... Gaulton KJ, et al. Multi-ancestry Polygenic Mechanisms of Type 2 Diabetes Elucidate Disease Processes and Clinical Heterogeneity. Medrxiv : the Preprint Server For Health Sciences. PMID 37808749 DOI: 10.1101/2023.09.28.23296294 |
0.319 |
|
| 2023 |
Kudtarkar P, Costanzo MC, Sun Y, Jang D, Koesterer R, Mychaleckyj JC, Nayak U, Onengut-Gumuscu S, Rich SS, Flannick JA, Gaulton KJ, Burtt NP. Leveraging type 1 diabetes human genetic and genomic data in the T1D knowledge portal. Plos Biology. 21: e3002233. PMID 37561710 DOI: 10.1371/journal.pbio.3002233 |
0.3 |
|
| 2023 |
Benaglio P, Newsome J, Han JY, Chiou J, Aylward A, Corban S, Miller M, Okino ML, Kaur J, Preissl S, Gorkin DU, Gaulton KJ. Mapping genetic effects on cell type-specific chromatin accessibility and annotating complex immune trait variants using single nucleus ATAC-seq in peripheral blood. Plos Genetics. 19: e1010759. PMID 37289818 DOI: 10.1371/journal.pgen.1010759 |
0.358 |
|
| 2023 |
Gaulton KJ, Preissl S, Ren B. Interpreting non-coding disease-associated human variants using single-cell epigenomics. Nature Reviews. Genetics. PMID 37161089 DOI: 10.1038/s41576-023-00598-6 |
0.378 |
|
| 2023 |
Costanzo MC, von Grotthuss M, Massung J, Jang D, Caulkins L, Koesterer R, Gilbert C, Welch RP, Kudtarkar P, Hoang Q, Boughton AP, Singh P, Sun Y, Duby M, Moriondo A, ... ... Gaulton KJ, et al. The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits. Cell Metabolism. PMID 36963395 DOI: 10.1016/j.cmet.2023.03.001 |
0.304 |
|
| 2023 |
Kudtarkar P, Costanzo MC, Sun Y, Jang D, Koesterer R, Mychaleckyj JC, Nayak U, Onengut-Gumuscu S, Rich SS, Flannick JA, Gaulton KJ, Burtt NP. Leveraging type 1 diabetes human genetic and genomic data in the T1D Knowledge Portal. Biorxiv : the Preprint Server For Biology. PMID 36778413 DOI: 10.1101/2023.02.03.526066 |
0.357 |
|
| 2022 |
Mahajan A, Spracklen CN, Zhang W, Ng MCY, Petty LE, Kitajima H, Yu GZ, Rüeger S, Speidel L, Kim YJ, Horikoshi M, Mercader JM, Taliun D, Moon S, Kwak SH, ... ... Gaulton KJ, et al. Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation. Nature Genetics. PMID 35551307 DOI: 10.1038/s41588-022-01058-3 |
0.622 |
|
| 2021 |
Chiou J, Geusz RJ, Okino ML, Han JY, Miller M, Melton R, Beebe E, Benaglio P, Huang S, Korgaonkar K, Heller S, Kleger A, Preissl S, Gorkin DU, Sander M, ... Gaulton KJ, et al. Interpreting type 1 diabetes risk with genetics and single-cell epigenomics. Nature. PMID 34012112 DOI: 10.1038/s41586-021-03552-w |
0.432 |
|
| 2021 |
Aylward A, Okino ML, Benaglio P, Chiou J, Beebe E, Padilla JA, Diep S, Gaulton KJ. Glucocorticoid signaling in pancreatic islets modulates gene regulatory programs and genetic risk of type 2 diabetes. Plos Genetics. 17: e1009531. PMID 33983929 DOI: 10.1371/journal.pgen.1009531 |
0.309 |
|
| 2021 |
Geusz RJ, Wang A, Chiou J, Lancman JJ, Wetton N, Kefalopoulou S, Wang J, Qui Y, Yan J, Aylward A, Ren B, Dong PDS, Gaulton KJ, Sander M. Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development. Elife. 10. PMID 33544077 DOI: 10.7554/eLife.59067 |
0.323 |
|
| 2021 |
Yan J, Qiu Y, Ribeiro Dos Santos AM, Yin Y, Li YE, Vinckier N, Nariai N, Benaglio P, Raman A, Li X, Fan S, Chiou J, Chen F, Frazer KA, Gaulton KJ, et al. Systematic analysis of binding of transcription factors to noncoding variants. Nature. PMID 33505025 DOI: 10.1038/s41586-021-03211-0 |
0.321 |
|
| 2020 |
Gorkin DU, Barozzi I, Zhao Y, Zhang Y, Huang H, Lee AY, Li B, Chiou J, Wildberg A, Ding B, Zhang B, Wang M, Strattan JS, Davidson JM, Qiu Y, ... ... Gaulton K, et al. An atlas of dynamic chromatin landscapes in mouse fetal development. Nature. 583: 744-751. PMID 32728240 DOI: 10.1038/S41586-020-2093-3 |
0.33 |
|
| 2020 |
Kim H, Grotthuss MV, Mercader JM, Chiou J, Gaulton KJ, Manning A, Florez JC, Udler M. 1644-P: High Throughput Approach Enables Expanded Clustering of Type 2 Diabetes Genetic Loci Informed by Phenotypic Associations Diabetes. 69. DOI: 10.2337/Db20-1644-P |
0.443 |
|
| 2019 |
Benaglio P, D'Antonio-Chronowska A, Ma W, Yang F, Young Greenwald WW, Donovan MKR, DeBoever C, Li H, Drees F, Singhal S, Matsui H, van Setten J, Sotoodehnia N, Gaulton KJ, Smith EN, et al. Allele-specific NKX2-5 binding underlies multiple genetic associations with human electrocardiographic traits. Nature Genetics. PMID 31570892 DOI: 10.1038/S41588-019-0499-3 |
0.514 |
|
| 2019 |
Greenwald WW, Chiou J, Yan J, Qiu Y, Dai N, Wang A, Nariai N, Aylward A, Han JY, Kadakia N, Regue L, Okino ML, Drees F, Kramer D, Vinckier N, ... ... Gaulton KJ, et al. Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk. Nature Communications. 10: 2078. PMID 31064983 DOI: 10.1038/S41467-019-09975-4 |
0.416 |
|
| 2019 |
Warrington NM, Beaumont RN, Horikoshi M, Day FR, Helgeland Ø, Laurin C, Bacelis J, Peng S, Hao K, Feenstra B, Wood AR, Mahajan A, Tyrrell J, Robertson NR, Rayner NW, ... ... Gaulton KJ, et al. Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Nature Genetics. PMID 31043758 DOI: 10.1038/S41588-019-0403-1 |
0.54 |
|
| 2019 |
Zhang Q, Chao TC, Patil VS, Qin Y, Tiwari SK, Chiou J, Dobin A, Tsai CM, Li Z, Dang J, Gupta S, Urdahl K, Nizet V, Gingeras TR, Gaulton KJ, et al. The long noncoding RNA regulates inflammatory gene expression. The Embo Journal. PMID 30918008 DOI: 10.15252/Embj.2018100041 |
0.325 |
|
| 2019 |
Fernández-Tajes J, Gaulton KJ, van de Bunt M, Torres J, Thurner M, Mahajan A, Gloyn AL, Lage K, McCarthy MI. Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data. Genome Medicine. 11: 19. PMID 30914061 DOI: 10.1186/S13073-019-0628-8 |
0.499 |
|
| 2019 |
Morris AP, Le TH, Wu H, Akbarov A, van der Most PJ, Hemani G, Smith GD, Mahajan A, Gaulton KJ, Nadkarni GN, Valladares-Salgado A, Wacher-Rodarte N, Mychaleckyj JC, Dueker ND, Guo X, et al. Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies. Nature Communications. 10: 29. PMID 30604766 DOI: 10.1038/S41467-018-07867-7 |
0.355 |
|
| 2019 |
WORTHAM M, LIU F, FLEISCHMAN J, WALLACE M, HARRINGTON AR, CHIOU J, GAULTON K, METALLO C, SANDER M. 4-LB: Feeding-Stimulated Regulation of the Epigenome Controls Adaptive Insulin Secretion Diabetes. 68: 4-LB. DOI: 10.2337/Db19-4-Lb |
0.345 |
|
| 2018 |
Aylward A, Chiou J, Okino ML, Kadakia N, Gaulton KJ. Shared genetic risk contributes to type 1 and type 2 diabetes etiology. Human Molecular Genetics. PMID 30407494 DOI: 10.1093/Hmg/Ddy314 |
0.504 |
|
| 2018 |
Udler MS, Kim J, von Grotthuss M, Bonàs-Guarch S, Cole JB, Chiou J, Boehnke M, Laakso M, Atzmon G, Glaser B, Mercader JM, Gaulton K, Flannick J, Getz G, et al. Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis. Plos Medicine. 15: e1002654. PMID 30240442 DOI: 10.1371/Journal.Pmed.1002654 |
0.418 |
|
| 2018 |
Liang J, Le TH, Velez Edwards DR, Tayo BO, Gaulton KJ, Smith JA, Lu Y, Jensen RA, Chen G, Yanek LR, Schwander K, Tajuddin SM, Sofer T, Kim W, Kayima J, et al. Correction: Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations. Plos Genetics. 14: e1007345. PMID 29750786 DOI: 10.1371/Journal.Pgen.1007345 |
0.418 |
|
| 2018 |
Thurner M, van de Bunt M, Torres JM, Mahajan A, Nylander V, Bennett AJ, Gaulton KJ, Barrett A, Burrows C, Bell CG, Lowe R, Beck S, Rakyan VK, Gloyn AL, McCarthy MI. Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci. Elife. 7. PMID 29412141 DOI: 10.7554/Elife.31977 |
0.496 |
|
| 2018 |
Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, et al. Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data. 5: 180002. PMID 29360107 DOI: 10.1038/sdata.2018.2 |
0.51 |
|
| 2018 |
Thurner M, Bunt Mvd, Torres JM, Mahajan A, Nylander V, Bennett AJ, Gaulton KJ, Barrett A, Burrows C, Bell CG, Lowe R, Beck S, Rakyan VK, Gloyn AL, McCarthy MI. Author response: Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci Elife. DOI: 10.7554/Elife.31977.047 |
0.426 |
|
| 2018 |
Mahajan A, Kitajima H, Sim X, Ng M, Zhang W, Below JE, Payne AJ, Gaulton K, Morris A. Discovery and Fine-Mapping of Type 2 Diabetes Susceptibility Loci in Diverse Populations Using More than a Million Individuals Diabetes. 67. DOI: 10.2337/Db18-212-Lb |
0.378 |
|
| 2017 |
Willems SM, Wright DJ, Day FR, Trajanoska K, Joshi PK, Morris JA, Matteini AM, Garton FC, Grarup N, Oskolkov N, Thalamuthu A, Mangino M, Liu J, Demirkan A, Lek M, ... ... Gaulton KJ, et al. Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness. Nature Communications. 8: 16015. PMID 29313844 DOI: 10.1038/Ncomms16015 |
0.375 |
|
| 2017 |
Jun G, Manning A, Almeida M, Zawistowski M, Wood AR, Teslovich TM, Fuchsberger C, Feng S, Cingolani P, Gaulton KJ, Dyer T, Blackwell TW, Chen H, Chines PS, Choi S, et al. Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees. Proceedings of the National Academy of Sciences of the United States of America. PMID 29279374 DOI: 10.1073/Pnas.1705859115 |
0.658 |
|
| 2017 |
Jason F, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, et al. Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data. 4: 170179. PMID 29257133 DOI: 10.1038/Sdata.2017.179 |
0.659 |
|
| 2017 |
Gaulton KJ. Mechanisms of Type 2 Diabetes Risk Loci. Current Diabetes Reports. 17: 72. PMID 28741265 DOI: 10.1007/S11892-017-0908-X |
0.395 |
|
| 2017 |
Scott RA, Scott LJ, Mägi R, Marullo L, Gaulton KJ, Kaakinen M, Pervjakova N, Pers TH, Johnson AD, Eicher JD, Jackson AU, Ferreira T, Lee Y, Ma C, Steinthorsdottir V, et al. An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. Diabetes. PMID 28566273 DOI: 10.2337/Db16-1253 |
0.701 |
|
| 2017 |
Liang J, Le TH, Edwards DRV, Tayo BO, Gaulton KJ, Smith JA, Lu Y, Jensen RA, Chen G, Yanek LR, Schwander K, Tajuddin SM, Sofer T, Kim W, Kayima J, et al. Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations. Plos Genetics. 13: e1006728. PMID 28498854 DOI: 10.1371/Journal.Pgen.1006728 |
0.458 |
|
| 2017 |
Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA, Mahajan A, Locke AE, Cingolani P, Pers TH, Viñuela A, Brown AA, Wu Y, ... ... Gaulton KJ, et al. A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. Diabetes. PMID 28341696 DOI: 10.2337/Db16-1329 |
0.639 |
|
| 2017 |
Carrat GR, Hu M, Nguyen-Tu MS, Chabosseau P, Gaulton KJ, van de Bunt M, Siddiq A, Falchi M, Thurner M, Canouil M, Pattou F, Leclerc I, Pullen TJ, Cane MC, Prabhala P, et al. Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice. American Journal of Human Genetics. PMID 28132686 DOI: 10.1016/J.Ajhg.2017.01.011 |
0.422 |
|
| 2016 |
Lotta LA, Gulati P, Day FR, Payne F, Ongen H, van de Bunt M, Gaulton KJ, Eicher JD, Sharp SJ, Luan J, De Lucia Rolfe E, Stewart ID, Wheeler E, Willems SM, Adams C, et al. Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance. Nature Genetics. PMID 27841877 DOI: 10.1038/Ng.3714 |
0.362 |
|
| 2016 |
Field Y, Boyle EA, Telis N, Gao Z, Gaulton KJ, Golan D, Yengo L, Rocheleau G, Froguel P, McCarthy MI, Pritchard JK. Detection of human adaptation during the past 2000 years. Science (New York, N.Y.). PMID 27738015 DOI: 10.1126/Science.Aag0776 |
0.422 |
|
| 2016 |
Horikoshi M, Beaumont RN, Day FR, Warrington NM, Kooijman MN, Fernandez-Tajes J, Feenstra B, van Zuydam NR, Gaulton KJ, Grarup N, Bradfield JP, Strachan DP, Li-Gao R, Ahluwalia TS, Kreiner E, et al. Genome-wide associations for birth weight and correlations with adult disease. Nature. PMID 27680694 DOI: 10.1038/Nature19806 |
0.655 |
|
| 2016 |
Mahajan A, Rodan AR, Le TH, Gaulton KJ, Haessler J, Stilp AM, Kamatani Y, Zhu G, Sofer T, Puri S, Schellinger JN, Chu PL, Cechova S, van Zuydam N, et al. Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity. American Journal of Human Genetics. 99: 636-646. PMID 27588450 DOI: 10.1016/J.Ajhg.2016.07.012 |
0.45 |
|
| 2016 |
Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P, Moutsianas L, McCarthy DJ, Rivas MA, Perry JR, Sim X, Blackwell TW, Robertson NR, et al. The genetic architecture of type 2 diabetes. Nature. PMID 27398621 DOI: 10.1038/Nature18642 |
0.666 |
|
| 2016 |
Liu CT, Raghavan S, Maruthur N, Kabagambe EK, Hong J, Ng MC, Hivert MF, Lu Y, An P, Bentley AR, Drolet AM, Gaulton KJ, Guo X, Armstrong LL, Irvin MR, et al. Trans-ethnic Meta-Analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin. American Journal of Human Genetics. PMID 27321945 DOI: 10.1016/J.Ajhg.2016.05.006 |
0.542 |
|
| 2015 |
Roman TS, Marvelle AF, Fogarty MP, Vadlamudi S, Gonzalez AJ, Buchkovich ML, Huyghe JR, Fuchsberger C, Jackson AU, Wu Y, Civelek M, Lusis AJ, Gaulton KJ, Sethupathy P, Kangas AJ, et al. Multiple Hepatic Regulatory Variants at the GALNT2 GWAS Locus Associated with High-Density Lipoprotein Cholesterol. American Journal of Human Genetics. 97: 801-15. PMID 26637976 DOI: 10.1016/J.Ajhg.2015.10.016 |
0.73 |
|
| 2015 |
van de Bunt M, Manning Fox JE, Dai X, Barrett A, Grey C, Li L, Bennett AJ, Johnson PR, Rajotte RV, Gaulton KJ, Dermitzakis ET, MacDonald PE, McCarthy MI, Gloyn AL. Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors. Plos Genetics. 11: e1005694. PMID 26624892 DOI: 10.1371/Journal.Pgen.1005694 |
0.542 |
|
| 2015 |
Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Mägi R, Reschen ME, Mahajan A, Locke A, William Rayner N, Robertson N, Scott RA, Prokopenko I, Scott LJ, Green T, Sparso T, et al. Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nature Genetics. PMID 26551672 DOI: 10.1038/Ng.3437 |
0.684 |
|
| 2015 |
Horikoshi M, M?gi R, van de Bunt M, Surakka I, Sarin AP, Mahajan A, Marullo L, Thorleifsson G, H?gg S, Hottenga JJ, Ladenvall C, Ried JS, Winkler TW, Willems SM, Pervjakova N, ... ... Gaulton KJ, et al. Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation. Plos Genetics. 11: e1005230. PMID 26132169 DOI: 10.1371/Journal.Pgen.1005230 |
0.507 |
|
| 2015 |
Moutsianas L, Agarwala V, Fuchsberger C, Flannick J, Rivas MA, Gaulton KJ, Albers PK, McVean G, Boehnke M, Altshuler D, McCarthy MI. The power of gene-based rare variant methods to detect disease-associated variation and test hypotheses about complex disease. Plos Genetics. 11: e1005165. PMID 25906071 DOI: 10.1371/Journal.Pgen.1005165 |
0.44 |
|
| 2015 |
Reschen ME, Gaulton KJ, Lin D, Soilleux EJ, Morris AJ, Smyth SS, O'Callaghan CA. Lipid-induced epigenomic changes in human macrophages identify a coronary artery disease-associated variant that regulates PPAP2B Expression through Altered C/EBP-beta binding. Plos Genetics. 11: e1005061. PMID 25835000 DOI: 10.1371/Journal.Pgen.1005061 |
0.433 |
|
| 2015 |
Mahajan A, Sim X, Ng HJ, Manning A, Rivas MA, Highland HM, Locke AE, Grarup N, Im HK, Cingolani P, Flannick J, Fontanillas P, Fuchsberger C, Gaulton KJ, Teslovich TM, et al. Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus. Plos Genetics. 11: e1004876. PMID 25625282 DOI: 10.1371/Journal.Pgen.1004876 |
0.688 |
|
| 2015 |
Wood AR, Tuke MA, Nalls M, Hernandez D, Gibbs JR, Lin H, Xu CS, Li Q, Shen J, Jun G, Almeida M, Tanaka T, Perry JR, Gaulton K, Rivas M, et al. Whole-genome sequencing to understand the genetic architecture of common gene expression and biomarker phenotypes. Human Molecular Genetics. 24: 1504-12. PMID 25378555 DOI: 10.1093/Hmg/Ddu560 |
0.515 |
|
| 2014 |
Fogarty MP, Cannon ME, Vadlamudi S, Gaulton KJ, Mohlke KL. Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus. Plos Genetics. 10: e1004633. PMID 25211022 DOI: 10.1371/Journal.Pgen.1004633 |
0.675 |
|
| 2014 |
Chambers JC, Abbott J, Zhang W, Turro E, Scott WR, Tan ST, Afzal U, Afaq S, Loh M, Lehne B, O'Reilly P, Gaulton KJ, Pearson RD, Li X, Lavery A, et al. The South Asian genome. Plos One. 9: e102645. PMID 25115870 DOI: 10.1371/Journal.Pone.0102645 |
0.496 |
|
| 2014 |
McCarthy DJ, Humburg P, Kanapin A, Rivas MA, Gaulton K, Cazier JB, Donnelly P. Choice of transcripts and software has a large effect on variant annotation. Genome Medicine. 6: 26. PMID 24944579 DOI: 10.1186/Gm543 |
0.411 |
|
| 2014 |
Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, et al. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature Genetics. 46: 234-44. PMID 24509480 DOI: 10.1038/Ng.2897 |
0.693 |
|
| 2014 |
Lange LA, Hu Y, Zhang H, Xue C, Schmidt EM, Tang ZZ, Bizon C, Lange EM, Smith JD, Turner EH, Jun G, Kang HM, Peloso G, Auer P, Li KP, ... ... Gaulton K, et al. Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. American Journal of Human Genetics. 94: 233-45. PMID 24507775 DOI: 10.1016/J.Ajhg.2014.01.010 |
0.476 |
|
| 2014 |
Pasquali L, Gaulton KJ, Rodríguez-Seguí SA, Mularoni L, Miguel-Escalada I, Akerman I, Tena JJ, Morán I, Gómez-Marín C, van de Bunt M, Ponsa-Cobas J, Castro N, Nammo T, Cebola I, García-Hurtado J, et al. Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants. Nature Genetics. 46: 136-43. PMID 24413736 DOI: 10.1038/Ng.2870 |
0.463 |
|
| 2013 |
Rivas MA, Pirinen M, Neville MJ, Gaulton KJ, Moutsianas L, Lindgren CM, Karpe F, McCarthy MI, Donnelly P. Assessing association between protein truncating variants and quantitative traits. Bioinformatics (Oxford, England). 29: 2419-26. PMID 23860716 DOI: 10.1093/Bioinformatics/Btt409 |
0.471 |
|
| 2010 |
Lange LA, Croteau-Chonka DC, Marvelle AF, Qin L, Gaulton KJ, Kuzawa CW, McDade TW, Wang Y, Li Y, Levy S, Borja JB, Lange EM, Adair LS, Mohlke KL. Genome-wide association study of homocysteine levels in Filipinos provides evidence for CPS1 in women and a stronger MTHFR effect in young adults. Human Molecular Genetics. 19: 2050-8. PMID 20154341 DOI: 10.1093/Hmg/Ddq062 |
0.682 |
|
| 2010 |
Gaulton KJ, Nammo T, Pasquali L, Simon JM, Giresi PG, Fogarty MP, Panhuis TM, Mieczkowski P, Secchi A, Bosco D, Berney T, Montanya E, Mohlke KL, Lieb JD, Ferrer J. A map of open chromatin in human pancreatic islets. Nature Genetics. 42: 255-9. PMID 20118932 DOI: 10.1038/Ng.530 |
0.626 |
|
| 2008 |
Gaulton KJ, Willer CJ, Li Y, Scott LJ, Conneely KN, Jackson AU, Duren WL, Chines PS, Narisu N, Bonnycastle LL, Luo J, Tong M, Sprau AG, Pugh EW, Doheny KF, et al. Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes. Diabetes. 57: 3136-44. PMID 18678618 DOI: 10.2337/Db07-1731 |
0.636 |
|
| 2007 |
Gaulton KJ, Mohlke KL, Vision TJ. A computational system to select candidate genes for complex human traits. Bioinformatics (Oxford, England). 23: 1132-40. PMID 17237041 DOI: 10.1093/Bioinformatics/Btm001 |
0.569 |
|
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