| Year |
Citation |
Score |
| 2015 |
Southwell AL, Franciosi S, Villanueva EB, Xie Y, Winter LA, Veeraraghavan J, Jonason A, Felczak B, Zhang W, Kovalik V, Waltl S, Hall G, Pouladi MA, Smith ES, Bowers WJ, et al. Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease. Neurobiology of Disease. 76: 46-56. PMID 25662335 DOI: 10.1016/J.Nbd.2015.01.002 |
0.361 |
|
| 2015 |
Evans EE, Jonason AS, Bussler H, Torno S, Veeraraghavan J, Reilly C, Doherty MA, Seils J, Winter LA, Mallow C, Kirk R, Howell A, Giralico S, Scrivens M, Klimatcheva K, ... ... Bowers WJ, et al. Antibody Blockade of Semaphorin 4D Promotes Immune Infiltration into Tumor and Enhances Response to Other Immunomodulatory Therapies. Cancer Immunology Research. 3: 689-701. PMID 25614511 DOI: 10.1158/2326-6066.Cir-14-0171 |
0.312 |
|
| 2014 |
Smith ES, Jonason A, Reilly C, Veeraraghavan J, Fisher T, Doherty M, Klimatcheva E, Mallow C, Cornelius C, Leonard JE, Marchi N, Janigro D, Argaw AT, Pham T, Seils J, ... ... Bowers WJ, et al. SEMA4D compromises blood-brain barrier, activates microglia, and inhibits remyelination in neurodegenerative disease. Neurobiology of Disease. 73: 254-268. PMID 25461192 DOI: 10.1016/J.Nbd.2014.10.008 |
0.355 |
|
| 2013 |
Montgomery SL, Narrow WC, Mastrangelo MA, Olschowka JA, O'Banion MK, Bowers WJ. Chronic neuron- and age-selective down-regulation of TNF receptor expression in triple-transgenic Alzheimer disease mice leads to significant modulation of amyloid- and Tau-related pathologies. The American Journal of Pathology. 182: 2285-97. PMID 23567638 DOI: 10.1016/J.Ajpath.2013.02.030 |
0.655 |
|
| 2012 |
Montgomery SL, Bowers WJ. Tumor necrosis factor-alpha and the roles it plays in homeostatic and degenerative processes within the central nervous system. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 42-59. PMID 21728035 DOI: 10.1007/S11481-011-9287-2 |
0.623 |
|
| 2011 |
Hadaczek P, Beyer J, Kells A, Narrow W, Bowers W, Federoff HJ, Forsayeth J, Bankiewicz KS. Evaluation of an AAV2-based rapamycin-regulated glial cell line-derived neurotrophic factor (GDNF) expression vector system. Plos One. 6: e27728. PMID 22132130 DOI: 10.1371/Journal.Pone.0027728 |
0.532 |
|
| 2011 |
Schnell L, Hunanyan AS, Bowers WJ, Horner PJ, Federoff HJ, Gullo M, Schwab ME, Mendell LM, Arvanian VL. Combined delivery of Nogo-A antibody, neurotrophin-3 and the NMDA-NR2d subunit establishes a functional 'detour' in the hemisected spinal cord. The European Journal of Neuroscience. 34: 1256-67. PMID 21995852 DOI: 10.1111/J.1460-9568.2011.07862.X |
0.485 |
|
| 2011 |
Hunter JM, Bowers WJ, Maarouf CL, Mastrangelo MA, Daugs ID, Kokjohn TA, Kalback WM, Luehrs DC, Valla J, Beach TG, Roher AE. Biochemical and morphological characterization of the AβPP/PS/tau triple transgenic mouse model and its relevance to sporadic Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 27: 361-76. PMID 21860086 DOI: 10.3233/Jad-2011-110608 |
0.373 |
|
| 2011 |
Montgomery SL, Mastrangelo MA, Habib D, Narrow WC, Knowlden SA, Wright TW, Bowers WJ. Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-α suppressive therapeutic strategies in the brain. The American Journal of Pathology. 179: 2053-70. PMID 21835156 DOI: 10.1016/J.Ajpath.2011.07.001 |
0.658 |
|
| 2011 |
Domm W, Brooks L, Chung HL, Feng C, Bowers WJ, Watson G, McGrath JL, Dewhurst S. Robust antigen-specific humoral immune responses to sublingually delivered adenoviral vectors encoding HIV-1 Env: association with mucoadhesion and efficient penetration of the sublingual barrier. Vaccine. 29: 7080-9. PMID 21801777 DOI: 10.1016/J.Vaccine.2011.07.008 |
0.368 |
|
| 2011 |
de Silva S, Bowers WJ. Targeting the central nervous system with herpes simplex virus / Sleeping Beauty hybrid amplicon vectors. Current Gene Therapy. 11: 332-40. PMID 21711226 DOI: 10.2174/156652311797415845 |
0.619 |
|
| 2011 |
Bowers WJ, Breakefield XO, Sena-Esteves M. Genetic therapy for the nervous system. Human Molecular Genetics. 20: R28-41. PMID 21429918 DOI: 10.1093/Hmg/Ddr110 |
0.309 |
|
| 2011 |
Desai MK, Guercio BJ, Narrow WC, Bowers WJ. An Alzheimer's disease-relevant presenilin-1 mutation augments amyloid-beta-induced oligodendrocyte dysfunction. Glia. 59: 627-40. PMID 21294162 DOI: 10.1002/Glia.21131 |
0.714 |
|
| 2011 |
Philippidou P, Valdez G, Akmentin W, Bowers WJ, Federoff HJ, Halegoua S. Trk retrograde signaling requires persistent, Pincher-directed endosomes. Proceedings of the National Academy of Sciences of the United States of America. 108: 852-7. PMID 21187387 DOI: 10.1073/Pnas.1015981108 |
0.493 |
|
| 2011 |
Roher A, Bowers W, Hunter J, Maarouf C, Daugs I, Valla J, Kokjohn T, Beach T. P3-036: Morphological and biochemical analysis of the 3xTg-Alzheimer's disease mouse model: Implications for sporadic Alzheimer's disease and the amyloid cascade hypothesis Alzheimer's & Dementia. 7: S526-S526. DOI: 10.1016/J.Jalz.2011.05.1475 |
0.346 |
|
| 2010 |
Ryan DA, Mastrangelo MA, Narrow WC, Sullivan MA, Federoff HJ, Bowers WJ. Aβ-directed Single-chain Antibody Delivery Via a Serotype-1 AAV Vector Improves Learning Behavior and Pathology in Alzheimer's Disease Mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1471-1481. PMID 28178507 DOI: 10.1038/mt.2010.111 |
0.689 |
|
| 2010 |
Lee BD, Shin JH, VanKampen J, Petrucelli L, West AB, Ko HS, Lee YI, Maguire-Zeiss KA, Bowers WJ, Federoff HJ, Dawson VL, Dawson TM. Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease. Nature Medicine. 16: 998-1000. PMID 20729864 DOI: 10.1038/Nm.2199 |
0.489 |
|
| 2010 |
Desai MK, Mastrangelo MA, Ryan DA, Sudol KL, Narrow WC, Bowers WJ. Early oligodendrocyte/myelin pathology in Alzheimer's disease mice constitutes a novel therapeutic target. The American Journal of Pathology. 177: 1422-35. PMID 20696774 DOI: 10.2353/Ajpath.2010.100087 |
0.788 |
|
| 2010 |
Kells AP, Eberling J, Su X, Pivirotto P, Bringas J, Hadaczek P, Narrow WC, Bowers WJ, Federoff HJ, Forsayeth J, Bankiewicz KS. Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9567-77. PMID 20631185 DOI: 10.1523/Jneurosci.0942-10.2010 |
0.614 |
|
| 2010 |
de Silva S, Lotta LT, Burris CA, Bowers WJ. Virion-associated cofactor high-mobility group DNA-binding protein-1 facilitates transposition from the herpes simplex virus/Sleeping Beauty amplicon vector platform. Human Gene Therapy. 21: 1615-22. PMID 20568967 DOI: 10.1089/Hum.2010.022 |
0.605 |
|
| 2010 |
Ryan DA, Mastrangelo MA, Narrow WC, Sullivan MA, Federoff HJ, Bowers WJ. Abeta-directed single-chain antibody delivery via a serotype-1 AAV vector improves learning behavior and pathology in Alzheimer's disease mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1471-81. PMID 20551911 DOI: 10.1038/Mt.2010.111 |
0.709 |
|
| 2010 |
de Silva S, Mastrangelo MA, Lotta LT, Burris CA, Izsvák Z, Ivics Z, Bowers WJ. Herpes simplex virus/Sleeping Beauty vector-based embryonic gene transfer using the HSB5 mutant: loss of apparent transposition hyperactivity in vivo. Human Gene Therapy. 21: 1603-13. PMID 20507234 DOI: 10.1089/Hum.2010.062 |
0.61 |
|
| 2010 |
Ryan DA, Narrow WC, Federoff HJ, Bowers WJ. An improved method for generating consistent soluble amyloid-beta oligomer preparations for in vitro neurotoxicity studies. Journal of Neuroscience Methods. 190: 171-9. PMID 20452375 DOI: 10.1016/J.Jneumeth.2010.05.001 |
0.681 |
|
| 2010 |
Xiong Y, Coombes CE, Kilaru A, Li X, Gitler AD, Bowers WJ, Dawson VL, Dawson TM, Moore DJ. GTPase activity plays a key role in the pathobiology of LRRK2. Plos Genetics. 6: e1000902. PMID 20386743 DOI: 10.1371/Journal.Pgen.1000902 |
0.332 |
|
| 2010 |
Park KM, Bowers WJ. Tumor necrosis factor-alpha mediated signaling in neuronal homeostasis and dysfunction. Cellular Signalling. 22: 977-83. PMID 20096353 DOI: 10.1016/J.Cellsig.2010.01.010 |
0.503 |
|
| 2010 |
Park KM, Yule DI, Bowers WJ. Impaired TNF-alpha control of IP3R-mediated Ca2+ release in Alzheimer's disease mouse neurons. Cellular Signalling. 22: 519-26. PMID 19922794 DOI: 10.1016/J.Cellsig.2009.11.006 |
0.542 |
|
| 2010 |
de Silva S, Mastrangelo MA, Lotta LT, Burris CA, Federoff HJ, Bowers WJ. Extending the transposable payload limit of Sleeping Beauty (SB) using the Herpes Simplex Virus (HSV)/SB amplicon-vector platform. Gene Therapy. 17: 424-31. PMID 19865178 DOI: 10.1038/Gt.2009.144 |
0.691 |
|
| 2010 |
Bowers WJ, Montogomery SL, Mastrangelo MA, Narrow WC. P1-318: Ablated TNF receptor expression differentially affects microglial activation and amyloid deposition in the 3xTg-AD mouse model Alzheimer's & Dementia. 6: S265-S266. DOI: 10.1016/J.Jalz.2010.05.871 |
0.347 |
|
| 2010 |
Bowers WJ, Desai MK, Mastrangelo MA, Ryan DA, Sudol KL, Narrow WC. P2-242: Oligodendrocyte cell lineage represents an amyloid beta 1-42 sensitive cell population leading to white matter alterations during early Alzheimer's disease Alzheimer's & Dementia. 6: S385-S385. DOI: 10.1016/J.Jalz.2010.05.1291 |
0.755 |
|
| 2009 |
Sudol KL, Mastrangelo MA, Narrow WC, Frazer ME, Levites YR, Golde TE, Federoff HJ, Bowers WJ. Generating Differentially Targeted Amyloid-β Specific Intrabodies as a Passive Vaccination Strategy for Alzheimer's Disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2031-2040. PMID 28178451 DOI: 10.1038/mt.2009.174 |
0.532 |
|
| 2009 |
de Silva S, Bowers WJ. Herpes Virus Amplicon Vectors. Viruses. 1: 594-629. PMID 19956558 DOI: 10.3390/V1030594 |
0.597 |
|
| 2009 |
Mastrangelo MA, Sudol KL, Narrow WC, Bowers WJ. Interferon-{gamma} differentially affects Alzheimer's disease pathologies and induces neurogenesis in triple transgenic-AD mice. The American Journal of Pathology. 175: 2076-88. PMID 19808651 DOI: 10.2353/Ajpath.2009.090059 |
0.446 |
|
| 2009 |
Park KM, Yule DI, Bowers WJ. Tumor necrosis factor-alpha-mediated regulation of the inositol 1,4,5-trisphosphate receptor promoter. The Journal of Biological Chemistry. 284: 27557-66. PMID 19666470 DOI: 10.1074/Jbc.M109.034504 |
0.484 |
|
| 2009 |
Sudol KL, Mastrangelo MA, Narrow WC, Frazer ME, Levites YR, Golde TE, Federoff HJ, Bowers WJ. Generating differentially targeted amyloid-beta specific intrabodies as a passive vaccination strategy for Alzheimer's disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2031-40. PMID 19638957 DOI: 10.1038/Mt.2009.174 |
0.562 |
|
| 2009 |
Chiu YG, Bowers WJ, Lim ST, Ryan DA, Federoff HJ. Effects of herpes simplex virus amplicon transduction on murine dendritic cells. Human Gene Therapy. 20: 442-52. PMID 19199821 DOI: 10.1089/Hum.2008.160 |
0.686 |
|
| 2009 |
Fiandaca MS, Varenika V, Eberling J, McKnight T, Bringas J, Pivirotto P, Beyer J, Hadaczek P, Bowers W, Park J, Federoff H, Forsayeth J, Bankiewicz KS. Real-time MR imaging of adeno-associated viral vector delivery to the primate brain Neuroimage. 47: T27-T35. PMID 19095069 DOI: 10.1016/J.Neuroimage.2008.11.012 |
0.51 |
|
| 2009 |
Daubeuf S, Singh D, Tan Y, Liu H, Federoff HJ, Bowers WJ, Tolba K. HSV ICP0 recruits USP7 to modulate TLR-mediated innate response. Blood. 113: 3264-75. PMID 18952891 DOI: 10.1182/Blood-2008-07-168203 |
0.525 |
|
| 2009 |
Desai MK, Sudol KL, Janelsins MC, Mastrangelo MA, Frazer ME, Bowers WJ. Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology. Glia. 57: 54-65. PMID 18661556 DOI: 10.1002/Glia.20734 |
0.765 |
|
| 2009 |
Federoff HJ, Chiu YG, Bowers WJ, Lim ST, Ryan DA. Effects of HSV amplicon transduction on murine dendritic cells Human Gene Therapy. 90126111624022. DOI: 10.1089/Hgt.2008.160 |
0.663 |
|
| 2008 |
Frazer ME, Hughes JE, Mastrangelo MA, Tibbens JL, Federoff HJ, Bowers WJ. Reduced Pathology and Improved Behavioral Performance in Alzheimer's Disease Mice Vaccinated With HSV Amplicons Expressing Amyloid-β and Interleukin-4. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 845-853. PMID 28178487 DOI: 10.1038/Mt.2008.39 |
0.594 |
|
| 2008 |
Janelsins MC, Mastrangelo MA, Park KM, Sudol KL, Narrow WC, Oddo S, LaFerla FM, Callahan LM, Federoff HJ, Bowers WJ. Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice. The American Journal of Pathology. 173: 1768-82. PMID 18974297 DOI: 10.2353/Ajpath.2008.080528 |
0.733 |
|
| 2008 |
Park KM, Yule DI, Bowers WJ. Tumor necrosis factor-alpha potentiates intraneuronal Ca2+ signaling via regulation of the inositol 1,4,5-trisphosphate receptor. The Journal of Biological Chemistry. 283: 33069-79. PMID 18838384 DOI: 10.1074/Jbc.M802209200 |
0.506 |
|
| 2008 |
Mastrangelo MA, Bowers WJ. Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice. Bmc Neuroscience. 9: 81. PMID 18700006 DOI: 10.1186/1471-2202-9-81 |
0.386 |
|
| 2008 |
Frazer ME, Hughes JE, Mastrangelo MA, Tibbens JL, Federoff HJ, Bowers WJ. Reduced pathology and improved behavioral performance in Alzheimer's disease mice vaccinated with HSV amplicons expressing amyloid-beta and interleukin-4. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 845-53. PMID 18388924 DOI: 10.1038/mt.2008.39 |
0.538 |
|
| 2008 |
Burris CA, de Silva S, Narrow WC, Casey AE, Lotta LT, Federoff HJ, Bowers WJ. Hexamethylene bisacetamide leads to reduced helper virus-free HSV-1 amplicon expression titers via suppression of ICP0. The Journal of Gene Medicine. 10: 152-64. PMID 18058952 DOI: 10.1002/Jgm.1130 |
0.705 |
|
| 2008 |
Nechushtan H, Pham D, Zhang Y, Morgensztern D, Yi KH, Shin SU, Federoff HJ, Bowers WJ, Tolba KA, Rosenblatt JD. Augmentation of anti-tumor responses of adoptively transferred CD8+T cells in the lymphopenic setting by HSV amplicon transduction. Cancer Immunology, Immunotherapy : Cii. 57: 663-75. PMID 17952436 DOI: 10.1007/S00262-007-0405-1 |
0.52 |
|
| 2008 |
Desai MK, Sudol KL, Janelsins MC, Mastrangelo MA, Frazer ME, Bowers WJ. P3-404: Triple-transgenic Alzheimer's disease mice exhibit marked abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology Alzheimer's & Dementia. 4: T640-T640. DOI: 10.1016/J.Jalz.2008.05.1975 |
0.753 |
|
| 2008 |
Bowers WJ, Janelsins MC, Federoff HJ. Gene therapy and vaccination Neuroimmune Pharmacology. 709-724. DOI: 10.1007/978-0-387-72573-4_48 |
0.593 |
|
| 2007 |
Yi KH, Nechushtan H, Bowers WJ, Walker GR, Zhang Y, Pham DG, Podack ER, Federoff HJ, Tolba KA, Rosenblatt JD. Adoptively transferred tumor-specific T cells stimulated ex vivo using herpes simplex virus amplicons encoding 4-1BBL persist in the host and show antitumor activity in vivo. Cancer Research. 67: 10027-37. PMID 17942937 DOI: 10.1158/0008-5472.Can-06-2391 |
0.54 |
|
| 2007 |
Duke CM, Maguire CA, Keefer MC, Federoff HJ, Bowers WJ, Dewhurst S. HSV-1 amplicon vectors elicit polyfunctional T cell responses to HIV-1 Env, and strongly boost responses to an adenovirus prime. Vaccine. 25: 7410-21. PMID 17868958 DOI: 10.1016/J.Vaccine.2007.08.015 |
0.532 |
|
| 2007 |
Peterson EB, Mastrangelo MA, Federoff HJ, Bowers WJ. Neuronal specificity of HSV/sleeping beauty amplicon transduction in utero is driven primarily by tropism and cell type composition. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1848-55. PMID 17653102 DOI: 10.1038/Sj.Mt.6300267 |
0.596 |
|
| 2007 |
Santos K, Sanfilippo CM, Narrow WC, Casey AE, Rodriguez-Colon SM, McDermott MP, Federoff HJ, Bowers WJ, Dewhurst S. Infectivity of herpes simplex virus type-1 (HSV-1) amplicon vectors in dendritic cells is determined by the helper virus strain used for packaging. Journal of Virological Methods. 145: 37-46. PMID 17606303 DOI: 10.1016/J.Jviromet.2007.05.013 |
0.532 |
|
| 2007 |
Santos K, Simon DA, Conway E, Bowers WJ, Mitra S, Foster TH, Lugade A, Lord EM, Federoff HJ, Dewhurst S, Frelinger JG. Spatial and temporal expression of herpes simplex virus type 1 amplicon-encoded genes: implications for their use as immunization vectors. Human Gene Therapy. 18: 93-105. PMID 17298238 DOI: 10.1089/Hum.2006.082 |
0.607 |
|
| 2007 |
Sortwell CE, Bowers WJ, Counts SE, Pitzer MR, Fleming MF, McGuire SO, Maguire-Zeiss KA, Federoff HJ, Collier TJ. Effects of ex vivo transduction of mesencephalic reaggregates with bcl-2 on grafted dopamine neuron survival. Brain Research. 1134: 33-44. PMID 17196186 DOI: 10.1016/J.Brainres.2006.11.079 |
0.58 |
|
| 2007 |
Santos K, Duke CM, Rodriguez-Colon SM, Dakwar A, Fan S, Keefer MC, Federoff HJ, Frelinger JG, Bowers WJ, Dewhurst S. Effect of promoter strength on protein expression and immunogenicity of an HSV-1 amplicon vector encoding HIV-1 Gag. Vaccine. 25: 1634-46. PMID 17145123 DOI: 10.1016/J.Vaccine.2006.11.004 |
0.574 |
|
| 2007 |
Tan Y, Rosenblatt JD, Federoff HJ, Bowers WJ, Tolba KA. Regulation of TLR Signaling by USP7. Blood. 110: 2300-2300. DOI: 10.1182/Blood.V110.11.2300.2300 |
0.538 |
|
| 2006 |
Halterman MW, Giuliano RE, Bowers WJ, Federoff HJ. Improved HSV-1 amplicon packaging using virion host shutoff mutants lacking mRNAse activity. The Journal of Gene Medicine. 8: 1320-8. PMID 16989006 DOI: 10.1002/Jgm.972 |
0.746 |
|
| 2006 |
Tyler CM, Wuertzer CA, Bowers WJ, Federoff HJ. HSV amplicons: neuro applications. Current Gene Therapy. 6: 337-50. PMID 16787185 DOI: 10.2174/156652306777592045 |
0.779 |
|
| 2006 |
Bowers WJ, Mastrangelo MA, Howard DF, Southerland HA, Maguire-Zeiss KA, Federoff HJ. Neuronal precursor-restricted transduction via in utero CNS gene delivery of a novel bipartite HSV amplicon/transposase hybrid vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 580-8. PMID 16412694 DOI: 10.1016/J.Ymthe.2005.11.011 |
0.6 |
|
| 2006 |
Arvanian VL, Bowers WJ, Anderson A, Horner PJ, Federoff HJ, Mendell LM. Combined delivery of neurotrophin-3 and NMDA receptors 2D subunit strengthens synaptic transmission in contused and staggered double hemisected spinal cord of neonatal rat. Experimental Neurology. 197: 347-52. PMID 16289170 DOI: 10.1016/J.Expneurol.2005.10.008 |
0.478 |
|
| 2006 |
Tolba KA, Bowers W, Tan Y, Daubeuf S, Federoff HJ, Rosenblatt JD. HSV ICP0 Inhibits TLR-Mediated NF-κB Response to TLR Signaling. Blood. 108: 5487-5487. DOI: 10.1182/blood.v108.11.5487.5487 |
0.46 |
|
| 2006 |
Janelsins MC, Mastrangelo MA, Park KM, Fowlkes KL, Kinsky M, Narrow WC, Oddo S, LaFerla FM, Federoff HJ, Bowers WJ. 248. Revealing the Role(s) of TNF-alpha in Early Alzheimer's Disease Via rAAV-Mediated Hippocampal Gene Transfer in a Triple Transgenic Mouse Model Molecular Therapy. 13: S95. DOI: 10.1016/J.Ymthe.2006.08.275 |
0.7 |
|
| 2006 |
Fowlkes KL, Mastrangelo MA, Narrow WC, Levites Y, Golde TE, Federoff HJ, Bowers WJ. 247. Devising Aβ-Specific Passive Immunization Strategies for Alzheimer's Disease Using rAAV Vector-Mediated scFv Antibody Delivery Molecular Therapy. 13: S94-S95. DOI: 10.1016/J.Ymthe.2006.08.274 |
0.574 |
|
| 2005 |
Federoff HJ, Bowers WJ. Immune shaping and the development of Alzheimer's disease vaccines. Science of Aging Knowledge Environment : Sage Ke. 2005: pe35. PMID 16293586 DOI: 10.1126/Sageke.2005.46.Pe35 |
0.549 |
|
| 2005 |
Reinblatt M, Pin RH, Bowers WJ, Federoff HJ, Fong Y. Herpes simplex virus amplicon delivery of a hypoxia-inducible soluble vascular endothelial growth factor receptor (sFlk-1) inhibits angiogenesis and tumor growth in pancreatic adenocarcinoma. Annals of Surgical Oncology. 12: 1025-36. PMID 16244806 DOI: 10.1245/Aso.2005.03.081 |
0.517 |
|
| 2005 |
Janelsins MC, Mastrangelo MA, Oddo S, LaFerla FM, Federoff HJ, Bowers WJ. Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice. Journal of Neuroinflammation. 2: 23. PMID 16232318 DOI: 10.1186/1742-2094-2-23 |
0.689 |
|
| 2005 |
Corso TD, Torres G, Goulah C, Roy I, Gambino AS, Nayda J, Buckley T, Stachowiak EK, Bergey EJ, Pudavar H, Dutta P, Bloom DC, Bowers WJ, Stachowiak MK. Transfection of tyrosine kinase deleted FGF receptor-1 into rat brain substantia nigra reduces the number of tyrosine hydroxylase expressing neurons and decreases concentration levels of striatal dopamine. Brain Research. Molecular Brain Research. 139: 361-6. PMID 16039006 DOI: 10.1016/J.Molbrainres.2005.05.032 |
0.317 |
|
| 2005 |
Gorantla S, Santos K, Meyer V, Dewhurst S, Bowers WJ, Federoff HJ, Gendelman HE, Poluektova L. Human dendritic cells transduced with herpes simplex virus amplicons encoding human immunodeficiency virus type 1 (HIV-1) gp120 elicit adaptive immune responses from human cells engrafted into NOD/SCID mice and confer partial protection against HIV-1 challenge. Journal of Virology. 79: 2124-32. PMID 15681415 DOI: 10.1128/Jvi.79.4.2124-2132.2005 |
0.532 |
|
| 2005 |
Bowers WJ, Mastrangelo MA, Stanley HA, Casey AE, Milo LJ, Federoff HJ. HSV amplicon-mediated Abeta vaccination in Tg2576 mice: differential antigen-specific immune responses. Neurobiology of Aging. 26: 393-407. PMID 15653168 DOI: 10.1016/J.Neurobiolaging.2004.04.006 |
0.578 |
|
| 2005 |
Daubeuf S, Rosenblatt JD, Bowers WJ, Federoff HJ, Tolba KA. HSV Encoded ICP-0 Inhibits TLR Signaling in CLL Cells by Targeting TRAF-6. Blood. 106: 2953-2953. DOI: 10.1182/Blood.V106.11.2953.2953 |
0.566 |
|
| 2005 |
Bowers WJ, Mastrangelo MA, Casey AE, Southerland HA, Maguire-Zeiss KA, Federoff HJ. 431. In Utero CNS Delivery of an Integrating HSV-1 Amplicon Vector Leads to Prolonged, Neuron-Specific Gene Expression Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.433 |
0.598 |
|
| 2004 |
Wang H, Yu SW, Koh DW, Lew J, Coombs C, Bowers W, Federoff HJ, Poirier GG, Dawson TM, Dawson VL. Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10963-73. PMID 15574746 DOI: 10.1523/Jneurosci.3461-04.2004 |
0.487 |
|
| 2004 |
Pin RH, Reinblatt M, Bowers WJ, Federoff HJ, Fong Y. Herpes simplex virus amplicon delivery of a hypoxia-inducible angiogenic inhibitor blocks capillary formation in hepatocellular carcinoma. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 8: 812-22; discussion 8. PMID 15531234 DOI: 10.1016/J.Gassur.2004.08.007 |
0.531 |
|
| 2004 |
Arvanian VL, Bowers WJ, Petruska JC, Motin V, Manuzon H, Narrow WC, Federoff HJ, Mendell LM. Viral delivery of NR2D subunits reduces Mg2+ block of NMDA receptor and restores NT-3-induced potentiation of AMPA-kainate responses in maturing rat motoneurons. Journal of Neurophysiology. 92: 2394-404. PMID 15152019 DOI: 10.1152/Jn.00278.2004 |
0.503 |
|
| 2004 |
Daubeuf S, Rosenblatt JD, Bowers WJ, Urbistondo NT, Federoff HJ, Tolba KA. HSV Amplicon Transduction Activates an Innate Immune Response in CLL B Cells;Implications for Immune Therapy and Vaccine Development. Blood. 104: 2514-2514. DOI: 10.1182/Blood.V104.11.2514.2514 |
0.566 |
|
| 2004 |
Bowers WJ, Mastrangelo MA, Stanley HA, Chiu Y, Federoff HJ. P4-340 Immunological assessment of acute CNS inflammatory processes elicited in an Alzheimer's disease mouse model following HSV amplicon-based Aβ vaccination Neurobiology of Aging. 25: S572. DOI: 10.1016/S0197-4580(04)81898-0 |
0.543 |
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| 2004 |
Callahan LM, Edwards K, Maguire-Zeiss KA, Bowers WJ, Narrow WC, Kang S, Mastrangelo MA, Giuliano RE, Federoff HJ. P3-259 Expression of pathogenic tau, P301L, leads to microtubule disruption in hippocampal neurons Neurobiology of Aging. 25: S428. DOI: 10.1016/S0197-4580(04)81409-X |
0.512 |
|
| 2004 |
Janelsins MC, Mastrangelo MA, Federoff HJ, Bowers WJ. 226. Developing a CNS-Specific Inflammatory Model To Investigate Gene Therapy/Inflammation Interactions in the Context of Neurodegeneration|[ast]| Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.170 |
0.71 |
|
| 2004 |
Stanley HA, Bowers WJ, Mastrangelo MA, Federoff HJ. 211. Creation of a HSV VP22-Sleeping Beauty Fusion Protein To Facilitate Integration of HSV-1 Amplicon Vectors|[ast]| Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.152 |
0.578 |
|
| 2004 |
Bowers WJ, Mastrangelo MA, Stanley HA, Chiu Y, Federoff HJ. 43. Immunological Response Characterization in an Alzheimer's Disease Mouse Model Following HSV Amplicon-Based A|[beta]| Vaccination|[ast]| Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.05.068 |
0.577 |
|
| 2003 |
Kyrkanides S, Miller Jn, Bowers WJ, Federoff HJ. Transcriptional and posttranslational regulation of Cre recombinase by RU486 as the basis for an enhanced inducible expression system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 790-5. PMID 14599812 DOI: 10.1016/J.Ymthe.2003.07.005 |
0.539 |
|
| 2003 |
Harvey BK, Chang CF, Chiang YH, Bowers WJ, Morales M, Hoffer BJ, Wang Y, Federoff HJ. HSV amplicon delivery of glial cell line-derived neurotrophic factor is neuroprotective against ischemic injury. Experimental Neurology. 183: 47-55. PMID 12957487 DOI: 10.1016/S0014-4886(03)00080-3 |
0.674 |
|
| 2003 |
Zhang Y, Hong Y, Bounhar Y, Blacker M, Roucou X, Tounekti O, Vereker E, Bowers WJ, Federoff HJ, Goodyer CG, LeBlanc A. p75 neurotrophin receptor protects primary cultures of human neurons against extracellular amyloid beta peptide cytotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7385-94. PMID 12917374 DOI: 10.1523/Jneurosci.23-19-07385.2003 |
0.49 |
|
| 2003 |
Bowers WJ, Olschowka JA, Federoff HJ. Immune responses to replication-defective HSV-1 type vectors within the CNS: implications for gene therapy. Gene Therapy. 10: 941-5. PMID 12756414 DOI: 10.1038/Sj.Gt.3302047 |
0.596 |
|
| 2003 |
Wang X, Wiley RD, Evans TG, Bowers WJ, Federoff HJ, Dewhurst S. Cellular immune responses to helper-free HSV-1 amplicon particles encoding HIV-1 gp120 are enhanced by DNA priming. Vaccine. 21: 2288-97. PMID 12744859 DOI: 10.1016/S0264-410X(03)00099-9 |
0.528 |
|
| 2003 |
Olschowka JA, Bowers WJ, Hurley SD, Mastrangelo MA, Federoff HJ. Helper-free HSV-1 amplicons elicit a markedly less robust innate immune response in the CNS. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 218-27. PMID 12597910 DOI: 10.1016/S1525-0016(02)00036-9 |
0.609 |
|
| 2003 |
Snyder JE, Bowers WJ, Livingstone AM, Lee FE, Federoff HJ, Mosmann TR. Measuring the frequency of mouse and human cytotoxic T cells by the Lysispot assay: independent regulation of cytokine secretion and short-term killing. Nature Medicine. 9: 231-5. PMID 12539041 DOI: 10.1038/Nm821 |
0.56 |
|
| 2002 |
Wang SW, Mu X, Bowers WJ, Klein WH. Retinal ganglion cell differentiation in cultured mouse retinal explants. Methods (San Diego, Calif.). 28: 448-56. PMID 12507463 DOI: 10.1016/S1046-2023(02)00264-5 |
0.351 |
|
| 2002 |
Tolba KA, Bowers WJ, Muller J, Housekneckt V, Giuliano RE, Federoff HJ, Rosenblatt JD. Herpes simplex virus (HSV) amplicon-mediated codelivery of secondary lymphoid tissue chemokine and CD40L results in augmented antitumor activity. Cancer Research. 62: 6545-51. PMID 12438249 |
0.496 |
|
| 2002 |
Maguire-Zeiss KA, Bowers WJ, Federoff HJ. Somatic mosaic approaches and the aging brain. Neurobiology of Aging. 23: 977-84. PMID 12392799 DOI: 10.1016/S0197-4580(02)00077-5 |
0.54 |
|
| 2002 |
Bowers WJ, Federoff HJ. Amyloid immunotherapy-engendered CNS inflammation. Neurobiology of Aging. 23: 675-6; discussion 68. PMID 12392770 DOI: 10.1016/S0197-4580(02)00035-0 |
0.529 |
|
| 2002 |
Tolba KA, Bowers WJ, Eling DJ, Casey AE, Kipps TJ, Federoff HJ, Rosenblatt JD. HSV amplicon-mediated delivery of LIGHT enhances the antigen-presenting capacity of chronic lymphocytic leukemia. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 455-63. PMID 12377186 DOI: 10.1006/Mthe.2002.0693 |
0.549 |
|
| 2002 |
Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJ, Poirier GG, Dawson TM, Dawson VL. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science (New York, N.Y.). 297: 259-63. PMID 12114629 DOI: 10.1126/Science.1072221 |
0.486 |
|
| 2002 |
Bowers WJ, Chen X, Guo H, Frisina DR, Federoff HJ, Frisina RD. Neurotrophin-3 transduction attenuates cisplatin spiral ganglion neuron ototoxicity in the cochlea. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 12-8. PMID 12095298 DOI: 10.1006/Mthe.2002.0627 |
0.581 |
|
| 2002 |
Detrait ER, Bowers WJ, Halterman MW, Giuliano RE, Bennice L, Federoff HJ, Richfield EK. Reporter gene transfer induces apoptosis in primary cortical neurons. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 723-30. PMID 12027556 DOI: 10.1006/Mthe.2002.0609 |
0.734 |
|
| 2002 |
Hocknell PK, Wiley RD, Wang X, Evans TG, Bowers WJ, Hanke T, Federoff HJ, Dewhurst S. Expression of human immunodeficiency virus type 1 gp120 from herpes simplex virus type 1-derived amplicons results in potent, specific, and durable cellular and humoral immune responses. Journal of Virology. 76: 5565-80. PMID 11991985 DOI: 10.1128/Jvi.76.11.5565-5580.2002 |
0.557 |
|
| 2002 |
Halaby IA, Lyden SP, Davies MG, Roztocil E, Salamone LJ, Brooks AI, Green RM, Federoff HJ, Bowers WJ. Glucocorticoid-regulated VEGF expression in ischemic skeletal muscle. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 300-6. PMID 11863420 DOI: 10.1006/Mthe.2002.0539 |
0.517 |
|
| 2002 |
Wang SW, Mu X, Bowers WJ, Kim DS, Plas DJ, Crair MC, Federoff HJ, Gan L, Klein WH. Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth. Development (Cambridge, England). 129: 467-77. PMID 11807038 |
0.438 |
|
| 2001 |
Maguire-Zeiss KA, Bowers WJ, Federoff HJ. HSV vector-mediated gene delivery to the central nervous system. Current Opinion in Molecular Therapeutics. 3: 482-90. PMID 11699893 |
0.549 |
|
| 2001 |
Willis RA, Bowers WJ, Turner MJ, Fisher TL, Abdul-Alim CS, Howard DF, Federoff HJ, Lord EM, Frelinger JG. Dendritic cells transduced with HSV-1 amplicons expressing prostate-specific antigen generate antitumor immunity in mice. Human Gene Therapy. 12: 1867-79. PMID 11589829 DOI: 10.1089/104303401753153929 |
0.563 |
|
| 2001 |
Ballas N, Battaglioli E, Atouf F, Andres ME, Chenoweth J, Anderson ME, Burger C, Moniwa M, Davie JR, Bowers WJ, Federoff HJ, Rose DW, Rosenfeld MG, Brehm P, Mandel G. Regulation of neuronal traits by a novel transcriptional complex. Neuron. 31: 353-65. PMID 11516394 DOI: 10.1016/S0896-6273(01)00371-3 |
0.525 |
|
| 2001 |
Tolba KA, Bowers WJ, Hilchey SP, Halterman MW, Howard DF, Giuliano RE, Federoff HJ, Rosenblatt JD. Development of herpes simplex virus-1 amplicon-based immunotherapy for chronic lymphocytic leukemia. Blood. 98: 287-95. PMID 11435295 DOI: 10.1182/Blood.V98.2.287 |
0.737 |
|
| 2001 |
Chen X, Frisina RD, Bowers WJ, Frisina DR, Federoff HJ. HSV amplicon-mediated neurotrophin-3 expression protects murine spiral ganglion neurons from cisplatin-induced damage. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 958-63. PMID 11407910 DOI: 10.1006/Mthe.2001.0334 |
0.592 |
|
| 2001 |
Bowers WJ, Howard DF, Brooks AI, Halterman MW, Federoff HJ. Expression of vhs and VP16 during HSV-1 helper virus-free amplicon packaging enhances titers. Gene Therapy. 8: 111-20. PMID 11313780 DOI: 10.1038/Sj.Gt.3301340 |
0.74 |
|
| 2001 |
Jackson M, Song W, Liu MY, Jin L, Dykes-Hoberg M, Lin CI, Bowers WJ, Federoff HJ, Sternweis PC, Rothstein JD. Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins. Nature. 410: 89-93. PMID 11242047 DOI: 10.1038/35065091 |
0.474 |
|
| 2001 |
Bowers WJ, Maguire-Zeiss KA, Harvey BK, Federoff HJ. Gene therapeutic approaches to the treatment of Parkinson's disease Clinical Neuroscience Research. 1: 483-495. DOI: 10.1016/S1566-2772(01)00026-3 |
0.676 |
|
| 2000 |
Brooks AI, Cory-Slechta DA, Bowers WJ, Murg SL, Federoff HJ. Enhanced learning in mice parallels vector-mediated nerve growth factor expression in hippocampus. Human Gene Therapy. 11: 2341-52. PMID 11096439 DOI: 10.1089/104303400750038453 |
0.497 |
|
| 2000 |
Bowers WJ, Howard DF, Federoff HJ. Discordance between expression and genome transfer titering of HSV amplicon vectors: recommendation for standardized enumeration. Molecular Therapy : the Journal of the American Society of Gene Therapy. 1: 294-9. PMID 10933945 DOI: 10.1006/Mthe.2000.0039 |
0.592 |
|
| 1999 |
Tolba K, Federoff HJ, Bowers W, Facciponte J, Baka J, Challita-Eid P, Rosenblatt JD. Helper-Free Herpes Simplex Virus Amplicons allow Efficient Transduction of Leukemia Cells with a costimulatory ligand without Loss of MHC-I Expression Journla of Immunotherapy. 22: 466. DOI: 10.1097/00002371-199909000-00058 |
0.549 |
|
| 1997 |
Baglia LA, Bowers WJ, Ruddell A. The avian C/EBPgamma gene encodes a highly conserved leucine zipper transcription factor. Gene. 190: 297-302. PMID 9197547 DOI: 10.1016/S0378-1119(97)00016-4 |
0.651 |
|
| 1997 |
Bowers WJ, Howard DF, Federoff HJ. Gene therapeutic strategies for neuroprotection: implications for Parkinson's disease. Experimental Neurology. 144: 58-68. PMID 9126153 DOI: 10.1006/Exnr.1996.6389 |
0.585 |
|
| 1996 |
Bowers WJ, Baglia LA, Ruddel A. Regulation of avian leukosis virus long terminal repeat-enhanced transcription by C/EBP-Rel interactions. Journal of Virology. 70: 3051-9. PMID 8627783 DOI: 10.1128/Jvi.70.5.3051-3059.1996 |
0.329 |
|
| 1994 |
Bowers WJ, Petrosino JF, Smith CD, Ruddell A. Transcriptional regulation of ALV bursal lymphomagenesis. Leukemia. 8: S211-3. PMID 8152295 |
0.609 |
|
| 1992 |
Bowers WJ, Ruddell A. a1/EBP: a leucine zipper protein that binds CCAAT/enhancer elements in the avian leukosis virus long terminal repeat enhancer. Journal of Virology. 66: 6578-86. PMID 1328681 DOI: 10.1128/Jvi.66.11.6578-6586.1992 |
0.635 |
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