Shimon Schuldiner, Ph.D. - Publications

Affiliations: 
Life Sciences Hebrew University, Jerusalem, Jerusalem, Israel 

150 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Reyes-Fernández EZ, Schuldiner S. Acidification of Cytoplasm in Escherichia coli Provides a Strategy to Cope with Stress and Facilitates Development of Antibiotic Resistance. Scientific Reports. 10: 9954. PMID 32561799 DOI: 10.1038/S41598-020-66890-1  0.338
2019 Alon Cudkowicz N, Schuldiner S. Deletion of the major Escherichia coli multidrug transporter AcrB reveals transporter plasticity and redundancy in bacterial cells. Plos One. 14: e0218828. PMID 31251753 DOI: 10.1371/Journal.Pone.0218828  0.509
2018 Yaffe D, Forrest LR, Schuldiner S. The ins and outs of vesicular monoamine transporters. The Journal of General Physiology. PMID 29666153 DOI: 10.1085/Jgp.201711980  0.541
2018 Schuldiner S. The Escherichia coli effluxome. Research in Microbiology. PMID 29574104 DOI: 10.1016/J.Resmic.2018.02.006  0.536
2016 Yaffe D, Vergara-Jaque A, Forrest LR, Schuldiner S. Emulating proton-induced conformational changes in the vesicular monoamine transporter VMAT2 by mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27821772 DOI: 10.1073/Pnas.1605162113  0.521
2016 Shuster Y, Steiner-Mordoch S, Alon Cudkowicz N, Schuldiner S. A Transporter Interactome Is Essential for the Acquisition of Antimicrobial Resistance to Antibiotics. Plos One. 11: e0152917. PMID 27050393 DOI: 10.1371/Journal.Pone.0152917  0.475
2015 Melchior DL, Brill S, Wright GE, Schuldiner S. A liposomal method for evaluation of inhibitors of H(+)-coupled multidrug transporters. Journal of Pharmacological and Toxicological Methods. 77: 53-57. PMID 26463179 DOI: 10.1016/J.Vascn.2015.09.007  0.514
2015 Brill S, Sade-Falk O, Elbaz-Alon Y, Schuldiner S. Specificity determinants in small multidrug transporters. Journal of Molecular Biology. 427: 468-77. PMID 25479374 DOI: 10.1016/J.Jmb.2014.11.015  0.52
2015 Vergara-Jaque A, Yaffe D, Shuster Y, Listov D, Meena S, Singh SK, Schuldiner S, Forrest LR. Carboxyl Residues Required for Transport by a Vesicular Monoamine Transporter Homolog from Brevibacillus Brevis (BbMAT) Biophysical Journal. 108: 462a. DOI: 10.1016/J.Bpj.2014.11.2522  0.571
2014 Yaffe D, Vergara-Jaque A, Shuster Y, Listov D, Meena S, Singh SK, Forrest LR, Schuldiner S. Functionally important carboxyls in a bacterial homologue of the vesicular monoamine transporter (VMAT). The Journal of Biological Chemistry. 289: 34229-40. PMID 25336661 DOI: 10.1074/Jbc.M114.607366  0.576
2014 Schuldiner S. Competition as a way of life for H(+)-coupled antiporters. Journal of Molecular Biology. 426: 2539-46. PMID 24862284 DOI: 10.1016/J.Jmb.2014.05.020  0.486
2014 Lohr C, Christensen AL, Veshaguri S, Tutkus M, Iversen L, Kemmer G, Yaffe D, Zollmann T, Curran P, Schuldiner S, Tampé R, Pomorski T, Mindell J, Stamou D. Single Liposomes Used to Study the Activity of Individual Transporters Biophysical Journal. 106: 229a. DOI: 10.1016/J.Bpj.2013.11.1339  0.401
2013 Ugolev Y, Segal T, Yaffe D, Gros Y, Schuldiner S. Identification of conformationally sensitive residues essential for inhibition of vesicular monoamine transport by the noncompetitive inhibitor tetrabenazine. The Journal of Biological Chemistry. 288: 32160-71. PMID 24062308 DOI: 10.1074/Jbc.M113.502971  0.564
2013 Nasie I, Steiner-Mordoch S, Schuldiner S. Topology determination of untagged membrane proteins. Methods in Molecular Biology (Clifton, N.J.). 1033: 121-30. PMID 23996174 DOI: 10.1007/978-1-62703-487-6_8  0.335
2013 Yaffe D, Radestock S, Shuster Y, Forrest LR, Schuldiner S. Identification of molecular hinge points mediating alternating access in the vesicular monoamine transporter VMAT2. Proceedings of the National Academy of Sciences of the United States of America. 110: E1332-41. PMID 23530208 DOI: 10.1073/Pnas.1220497110  0.532
2012 Nasie I, Steiner-Mordoch S, Schuldiner S. New substrates on the block: clinically relevant resistances for EmrE and homologues. Journal of Bacteriology. 194: 6766-70. PMID 23042996 DOI: 10.1128/Jb.01318-12  0.444
2012 Brill S, Falk OS, Schuldiner S. Transforming a drug/H+ antiporter into a polyamine importer by a single mutation. Proceedings of the National Academy of Sciences of the United States of America. 109: 16894-9. PMID 23035252 DOI: 10.1073/Pnas.1211831109  0.427
2012 Schuldiner S. Undecided membrane proteins insert in random topologies. Up, down and sideways: it does not really matter. Trends in Biochemical Sciences. 37: 215-9. PMID 22444835 DOI: 10.1016/J.Tibs.2012.02.006  0.4
2010 Elbaz Y, Danieli T, Kanner BI, Schuldiner S. Expression of neurotransmitter transporters for structural and biochemical studies. Protein Expression and Purification. 73: 152-60. PMID 20566324 DOI: 10.1016/J.Pep.2010.06.001  0.516
2010 Nasie I, Steiner-Mordoch S, Gold A, Schuldiner S. Topologically random insertion of EmrE supports a pathway for evolution of inverted repeats in ion-coupled transporters. The Journal of Biological Chemistry. 285: 15234-44. PMID 20308069 DOI: 10.1074/Jbc.M110.108746  0.534
2010 Gros Y, Schuldiner S. Directed evolution reveals hidden properties of VMAT, a neurotransmitter transporter. The Journal of Biological Chemistry. 285: 5076-84. PMID 20007701 DOI: 10.1074/Jbc.M109.081216  0.529
2009 Miller D, Charalambous K, Rotem D, Schuldiner S, Curnow P, Booth PJ. In vitro unfolding and refolding of the small multidrug transporter EmrE. Journal of Molecular Biology. 393: 815-32. PMID 19699749 DOI: 10.1016/J.Jmb.2009.08.039  0.397
2009 Tal N, Schuldiner S. A coordinated network of transporters with overlapping specificities provides a robust survival strategy. Proceedings of the National Academy of Sciences of the United States of America. 106: 9051-6. PMID 19451626 DOI: 10.1073/Pnas.0902400106  0.516
2009 Schuldiner S. EmrE, a model for studying evolution and mechanism of ion-coupled transporters. Biochimica Et Biophysica Acta. 1794: 748-62. PMID 19167526 DOI: 10.1016/J.Bbapap.2008.12.018  0.53
2008 Elbaz Y, Salomon T, Schuldiner S. Identification of a glycine motif required for packing in EmrE, a multidrug transporter from Escherichia coli. The Journal of Biological Chemistry. 283: 12276-83. PMID 18321856 DOI: 10.1074/Jbc.M710338200  0.528
2008 Adam Y, Edwards RH, Schuldiner S. Expression and function of the rat vesicular monoamine transporter 2. American Journal of Physiology. Cell Physiology. 294: C1004-11. PMID 18287335 DOI: 10.1152/Ajpcell.00348.2007  0.798
2008 Steiner-Mordoch S, Soskine M, Solomon D, Rotem D, Gold A, Yechieli M, Adam Y, Schuldiner S. Parallel topology of genetically fused EmrE homodimers. The Embo Journal. 27: 17-26. PMID 18059473 DOI: 10.1038/Sj.Emboj.7601951  0.789
2007 Adam Y, Tayer N, Rotem D, Schreiber G, Schuldiner S. The fast release of sticky protons: kinetics of substrate binding and proton release in a multidrug transporter. Proceedings of the National Academy of Sciences of the United States of America. 104: 17989-94. PMID 17984053 DOI: 10.1073/Pnas.0704425104  0.762
2007 Agarwal V, Fink U, Schuldiner S, Reif B. MAS solid-state NMR studies on the multidrug transporter EmrE. Biochimica Et Biophysica Acta. 1768: 3036-43. PMID 17976529 DOI: 10.1016/J.Bbamem.2007.09.012  0.418
2007 Schuldiner S. Controversy over EmrE structure. Science (New York, N.Y.). 317: 748-51; author reply. PMID 17690276 DOI: 10.1126/Science.317.5839.748D  0.377
2007 Schuldiner S. When biochemistry meets structural biology: the cautionary tale of EmrE. Trends in Biochemical Sciences. 32: 252-8. PMID 17452106 DOI: 10.1016/J.Tibs.2007.04.002  0.398
2006 Soskine M, Mark S, Tayer N, Mizrachi R, Schuldiner S. On parallel and antiparallel topology of a homodimeric multidrug transporter. The Journal of Biological Chemistry. 281: 36205-12. PMID 17003034 DOI: 10.1074/Jbc.M607186200  0.423
2006 Schuldiner S. Structural biology: the ins and outs of drug transport. Nature. 443: 156-7. PMID 16971936 DOI: 10.1038/443156B  0.476
2006 Rotem D, Steiner-Mordoch S, Schuldiner S. Identification of tyrosine residues critical for the function of an ion-coupled multidrug transporter. The Journal of Biological Chemistry. 281: 18715-22. PMID 16672221 DOI: 10.1074/Jbc.M602088200  0.564
2005 Sigal N, Vardy E, Molshanski-Mor S, Eitan A, Pilpel Y, Schuldiner S, Bibi E. 3D model of the Escherichia coli multidrug transporter MdfA reveals an essential membrane-embedded positive charge. Biochemistry. 44: 14870-80. PMID 16274234 DOI: 10.1021/Bi051574P  0.382
2005 Vardy E, Steiner-Mordoch S, Schuldiner S. Characterization of bacterial drug antiporters homologous to mammalian neurotransmitter transporters. Journal of Bacteriology. 187: 7518-25. PMID 16237035 DOI: 10.1128/Jb.187.21.7518-7525.2005  0.498
2005 Sharoni M, Steiner-Mordoch S, Schuldiner S. Exploring the binding domain of EmrE, the smallest multidrug transporter. The Journal of Biological Chemistry. 280: 32849-55. PMID 16049002 DOI: 10.1074/Jbc.M504910200  0.475
2005 Elbaz Y, Tayer N, Steinfels E, Steiner-Mordoch S, Schuldiner S. Substrate-induced tryptophan fluorescence changes in EmrE, the smallest ion-coupled multidrug transporter. Biochemistry. 44: 7369-77. PMID 15882076 DOI: 10.1021/Bi050356T  0.484
2005 Weinglass AB, Soskine M, Vazquez-Ibar JL, Whitelegge JP, Faull KF, Kaback HR, Schuldiner S. Exploring the role of a unique carboxyl residue in EmrE by mass spectrometry. The Journal of Biological Chemistry. 280: 7487-92. PMID 15623511 DOI: 10.1074/Jbc.M413555200  0.424
2004 Rotem D, Schuldiner S. EmrE, a multidrug transporter from Escherichia coli, transports monovalent and divalent substrates with the same stoichiometry. The Journal of Biological Chemistry. 279: 48787-93. PMID 15371426 DOI: 10.1074/Jbc.M408187200  0.555
2004 Vardy E, Arkin IT, Gottschalk KE, Kaback HR, Schuldiner S. Structural conservation in the major facilitator superfamily as revealed by comparative modeling. Protein Science : a Publication of the Protein Society. 13: 1832-40. PMID 15215526 DOI: 10.1110/Ps.04657704  0.465
2004 Gottschalk KE, Soskine M, Schuldiner S, Kessler H. A structural model of EmrE, a multi-drug transporter from Escherichia coli. Biophysical Journal. 86: 3335-48. PMID 15189838 DOI: 10.1529/Biophysj.103.034546  0.498
2004 Ninio S, Elbaz Y, Schuldiner S. The membrane topology of EmrE - a small multidrug transporter from Escherichia coli. Febs Letters. 562: 193-6. PMID 15044024 DOI: 10.1016/S0014-5793(04)00240-6  0.481
2004 Elbaz Y, Steiner-Mordoch S, Danieli T, Schuldiner S. In vitro synthesis of fully functional EmrE, a multidrug transporter, and study of its oligomeric state. Proceedings of the National Academy of Sciences of the United States of America. 101: 1519-24. PMID 14755055 DOI: 10.1073/Pnas.0306533101  0.519
2004 Soskine M, Adam Y, Schuldiner S. Direct evidence for substrate-induced proton release in detergent-solubilized EmrE, a multidrug transporter. The Journal of Biological Chemistry. 279: 9951-5. PMID 14701800 DOI: 10.1074/Jbc.M312853200  0.776
2003 Ubarretxena-Belandia I, Baldwin JM, Schuldiner S, Tate CG. Three-dimensional structure of the bacterial multidrug transporter EmrE shows it is an asymmetric homodimer. The Embo Journal. 22: 6175-81. PMID 14633977 DOI: 10.1093/Emboj/Cdg611  0.457
2003 Gutman N, Steiner-Mordoch S, Schuldiner S. An amino acid cluster around the essential Glu-14 is part of the substrate- and proton-binding domain of EmrE, a multidrug transporter from Escherichia coli. The Journal of Biological Chemistry. 278: 16082-7. PMID 12590142 DOI: 10.1074/Jbc.M213120200  0.494
2003 Ninio S, Schuldiner S. Characterization of an archaeal multidrug transporter with a unique amino acid composition. The Journal of Biological Chemistry. 278: 12000-5. PMID 12551892 DOI: 10.1074/Jbc.M213119200  0.483
2002 Soskine M, Steiner-Mordoch S, Schuldiner S. Crosslinking of membrane-embedded cysteines reveals contact points in the EmrE oligomer. Proceedings of the National Academy of Sciences of the United States of America. 99: 12043-8. PMID 12221291 DOI: 10.1073/Pnas.192392899  0.4
2001 Ninio S, Rotem D, Schuldiner S. Functional analysis of novel multidrug transporters from human pathogens. The Journal of Biological Chemistry. 276: 48250-6. PMID 11574548 DOI: 10.1074/Jbc.M108231200  0.499
2001 Rotem D, Sal-man N, Schuldiner S. In vitro monomer swapping in EmrE, a multidrug transporter from Escherichia coli, reveals that the oligomer is the functional unit. The Journal of Biological Chemistry. 276: 48243-9. PMID 11572877 DOI: 10.1074/Jbc.M108229200  0.507
2001 Schuldiner S, Granot D, Mordoch SS, Ninio S, Rotem D, Soskin M, Tate CG, Yerushalmi H. Small is mighty: EmrE, a multidrug transporter as an experimental paradigm. News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 16: 130-4. PMID 11443233  0.453
2001 Yelin R, Schuldiner S. Vesicular monoamine transporters heterologously expressed in the yeast Saccharomyces cerevisiae display high-affinity tetrabenazine binding. Biochimica Et Biophysica Acta. 1510: 426-41. PMID 11342177 DOI: 10.1016/S0005-2736(00)00374-6  0.498
2001 Schuldiner S, Granot D, Steiner S, Ninio S, Rotem D, Soskin M, Yerushalmi H. Precious things come in little packages. Journal of Molecular Microbiology and Biotechnology. 3: 155-62. PMID 11321568  0.493
2001 Yerushalmi H, Mordoch SS, Schuldiner S. A single carboxyl mutant of the multidrug transporter EmrE is fully functional. The Journal of Biological Chemistry. 276: 12744-8. PMID 11278804 DOI: 10.1074/Jbc.M010979200  0.529
2001 Tate CG, Kunji ER, Lebendiker M, Schuldiner S. The projection structure of EmrE, a proton-linked multidrug transporter from Escherichia coli, at 7 A resolution. The Embo Journal. 20: 77-81. PMID 11226157 DOI: 10.1093/Emboj/20.1.77  0.411
2000 Yerushalmi H, Schuldiner S. A model for coupling of H(+) and substrate fluxes based on "time-sharing" of a common binding site. Biochemistry. 39: 14711-9. PMID 11101285 DOI: 10.1021/Bi001892I  0.544
2000 Glaubitz C, Gröger A, Gottschalk K, Spooner P, Watts A, Schuldiner S, Kessler H. 31P-CP-MAS NMR studies on TPP+ bound to the ion-coupled multidrug transport protein EmrE. Febs Letters. 480: 127-31. PMID 11034313 DOI: 10.1016/S0014-5793(00)01916-5  0.431
2000 Yerushalmi H, Schuldiner S. A common binding site for substrates and protons in EmrE, an ion-coupled multidrug transporter. Febs Letters. 476: 93-7. PMID 10878258 DOI: 10.1042/Bst028A143A  0.534
2000 Yerushalmi H, Schuldiner S. An essential glutamyl residue in EmrE, a multidrug antiporter from Escherichia coli. The Journal of Biological Chemistry. 275: 5264-9. PMID 10681497 DOI: 10.1074/Jbc.275.8.5264  0.514
2000 Muth TR, Schuldiner S. A membrane-embedded glutamate is required for ligand binding to the multidrug transporter EmrE. The Embo Journal. 19: 234-40. PMID 10637227 DOI: 10.1093/Emboj/19.2.234  0.506
1999 Williams KA, Geldmacher-Kaufer U, Padan E, Schuldiner S, Kühlbrandt W. Projection structure of NhaA, a secondary transporter from Escherichia coli, at 4.0 A resolution. The Embo Journal. 18: 3558-63. PMID 10393172 DOI: 10.1093/Emboj/18.13.3558  0.395
1999 Mordoch SS, Granot D, Lebendiker M, Schuldiner S. Scanning cysteine accessibility of EmrE, an H+-coupled multidrug transporter from Escherichia coli, reveals a hydrophobic pathway for solutes. The Journal of Biological Chemistry. 274: 19480-6. PMID 10383465 DOI: 10.1074/Jbc.274.27.19480  0.494
1999 Yelin R, Rotem D, Schuldiner S. EmrE, a small Escherichia coli multidrug transporter, protects Saccharomyces cerevisiae from toxins by sequestration in the vacuole. Journal of Bacteriology. 181: 949-56. PMID 9922260 DOI: 10.1128/Jb.181.3.949-956.1999  0.457
1998 Yelin R, Steiner-Mordoch S, Aroeti B, Schuldiner S. Glycosylation of a vesicular monoamine transporter: a mutation in a conserved proline residue affects the activity, glycosylation, and localization of the transporter. Journal of Neurochemistry. 71: 2518-27. PMID 9832151 DOI: 10.1046/J.1471-4159.1998.71062518.X  0.488
1998 Yelin R, Schuldiner S. Purification of vesicular monoamine transporters: from classical techniques to histidine tags. Methods in Enzymology. 296: 64-72. PMID 9779440 DOI: 10.1016/S0076-6879(98)96006-2  0.575
1998 Schwaiger M, Lebendiker M, Yerushalmi H, Coles M, Gröger A, Schwarz C, Schuldiner S, Kessler H. NMR investigation of the multidrug transporter EmrE, an integral membrane protein. European Journal of Biochemistry / Febs. 254: 610-9. PMID 9688273 DOI: 10.1046/J.1432-1327.1998.2540610.X  0.467
1998 Schuldiner S, Steiner-Mordoch S, Yelin R. Molecular and biochemical studies of rat vesicular monoamine transporter. Advances in Pharmacology (San Diego, Calif.). 42: 223-7. PMID 9327884 DOI: 10.1016/S1054-3589(08)60733-4  0.586
1997 Rothman A, Gerchman Y, Padan E, Schuldiner S. Probing the conformation of NhaA, a Na+/H+ antiporter from Escherichia coli, with trypsin. Biochemistry. 36: 14572-6. PMID 9398175 DOI: 10.1021/Bi971800Y  0.36
1997 Klyachko KA, Schuldiner S, Neyfakh AA. Mutations affecting substrate specificity of the Bacillus subtilis multidrug transporter Bmr. Journal of Bacteriology. 179: 2189-93. PMID 9079903  0.449
1997 Schuldiner S, Lebendiker M, Yerushalmi H. EmrE, the smallest ion-coupled transporter, provides a unique paradigm for structure-function studies. The Journal of Experimental Biology. 200: 335-41. PMID 9050242  0.406
1997 Yelin R, Mordoch S, Schuldiner S. The role of glycosylation in the vesicular monoamine transporter Neuroscience Letters. 237: S53. DOI: 10.1016/S0304-3940(97)90219-6  0.51
1996 Rothman A, Padan E, Schuldiner S. Topological analysis of NhaA, a Na+/H+ antiporter from Escherichia coli. The Journal of Biological Chemistry. 271: 32288-92. PMID 8943289 DOI: 10.1074/Jbc.271.50.32288  0.352
1996 Yerushalmi H, Lebendiker M, Schuldiner S. Negative dominance studies demonstrate the oligomeric structure of EmrE, a multidrug antiporter from Escherichia coli. The Journal of Biological Chemistry. 271: 31044-8. PMID 8940098 DOI: 10.1074/Jbc.271.49.31044  0.475
1996 Lebendiker M, Schuldiner S. Identification of residues in the translocation pathway of EmrE, a multidrug antiporter from Escherichia coli. The Journal of Biological Chemistry. 271: 21193-9. PMID 8702890 DOI: 10.1074/Jbc.271.35.21193  0.509
1996 Arkin IT, Russ WP, Lebendiker M, Schuldiner S. Determining the secondary structure and orientation of EmrE, a multi-drug transporter, indicates a transmembrane four-helix bundle. Biochemistry. 35: 7233-8. PMID 8679552 DOI: 10.1021/Bi960094I  0.391
1996 Steiner-Mordoch S, Shirvan A, Schuldiner S. Modification of the pH profile and tetrabenazine sensitivity of rat VMAT1 by replacement of aspartate 404 with glutamate. The Journal of Biological Chemistry. 271: 13048-54. PMID 8662678 DOI: 10.1074/Jbc.271.22.13048  0.557
1996 Schuldiner S, Lebendiker M, Mordoch S, Yelin R, Yerushalmi H. Chapter 18 From multidrug resistance to vesicular neurotransmitter transport Handbook of Biological Physics. 2: 405-431. DOI: 10.1016/S1383-8121(96)80059-5  0.374
1995 Yelin R, Schuldiner S. The pharmacological profile of the vesicular monoamine transporter resembles that of multidrug transporters. Febs Letters. 377: 201-7. PMID 8543051 DOI: 10.1016/0014-5793(95)01346-6  0.575
1995 Yerushalmi H, Lebendiker M, Schuldiner S. EmrE, an Escherichia coli 12-kDa multidrug transporter, exchanges toxic cations and H+ and is soluble in organic solvents. The Journal of Biological Chemistry. 270: 6856-63. PMID 7896833 DOI: 10.1074/Jbc.270.12.6856  0.556
1995 Harel-Bronstein M, Dibrov P, Olami Y, Pinner E, Schuldiner S, Padan E. MH1, a second-site revertant of an Escherichia coli mutant lacking Na+/H+ antiporters (delta nhaA delta nhaB), regains Na+ resistance and a capacity to excrete Na+ in a delta microH(+)-independent fashion. The Journal of Biological Chemistry. 270: 3816-22. PMID 7876124 DOI: 10.1074/Jbc.270.8.3816  0.368
1995 Pinner E, Padan E, Schuldiner S. Amiloride and harmaline are potent inhibitors of NhaB, a Na+/H+ antiporter from Escherichia coli. Febs Letters. 365: 18-22. PMID 7774707 DOI: 10.1016/0014-5793(95)00364-F  0.406
1995 Schuldiner S, Shirvan A, Linial M. Vesicular neurotransmitter transporters: from bacteria to humans. Physiological Reviews. 75: 369-92. PMID 7724667 DOI: 10.1152/Physrev.1995.75.2.369  0.474
1995 Rimon A, Gerchman Y, Olami Y, Schuldiner S, Padan E. Replacements of histidine 226 of NhaA-Na+/H+ antiporter of Escherichia coli. Cysteine (H226C) or serine (H226S) retain both normal activity and pH sensitivity, aspartate (H226D) shifts the pH profile toward basic pH, and alanine (H226A) inactivates the carrier at all pH values. The Journal of Biological Chemistry. 270: 26813-7. PMID 7592922 DOI: 10.1074/Jbc.270.45.26813  0.337
1994 Howell M, Shirvan A, Stern-Bach Y, Steiner-Mordoch S, Strasser JE, Dean GE, Schuldiner S. Cloning and functional expression of a tetrabenazine sensitive vesicular monoamine transporter from bovine chromaffin granules. Febs Letters. 338: 16-22. PMID 8307150 DOI: 10.1016/0014-5793(94)80108-8  0.766
1994 Carmel O, Dover N, Rahav-Manor O, Dibrov P, Kirsch D, Karpel R, Schuldiner S, Padan E. A single amino acid substitution (Glu134-->Ala) in NhaR1 increases the inducibility by Na+ of the product of nhaA, a Na+/H+ antiporter gene in Escherichia coli. The Embo Journal. 13: 1981-9. PMID 8168494 DOI: 10.1002/J.1460-2075.1994.Tb06467.X  0.374
1994 Padan E, Schuldiner S. Molecular physiology of Na+/H+ antiporters, key transporters in circulation of Na+ and H+ in cells. Biochimica Et Biophysica Acta. 1185: 129-51. PMID 8167133 DOI: 10.1016/0005-2728(94)90204-6  0.428
1994 Padan E, Schuldiner S. Molecular biology of Na+/H+ antiporters: molecular devices that couple the Na+ and H+ circulation in cells. Biochimica Et Biophysica Acta. 1187: 206-10. PMID 8075114 DOI: 10.1016/0005-2728(94)90112-0  0.319
1994 Shirvan A, Laskar O, Steiner-Mordoch S, Schuldiner S. Histidine-419 plays a role in energy coupling in the vesicular monoamine transporter from rat. Febs Letters. 356: 145-50. PMID 7988710 DOI: 10.1016/0014-5793(94)01252-0  0.524
1994 Schuldiner S, Shirvan A, Stern-Bach Y, Steiner-Mordoch S, Yelin R, Laskar O. From bacterial antibiotic resistance to neurotransmitter uptake. A common theme of cell survival. Annals of the New York Academy of Sciences. 733: 174-84. PMID 7978865 DOI: 10.1111/J.1749-6632.1994.Tb17267.X  0.696
1994 Pinner E, Padan E, Schuldiner S. Kinetic properties of NhaB, a Na+/H+ antiporter from Escherichia coli. The Journal of Biological Chemistry. 269: 26274-9. PMID 7929345  0.348
1994 Schuldiner S. A molecular glimpse of vesicular monoamine transporters. Journal of Neurochemistry. 62: 2067-78. PMID 7910628 DOI: 10.1046/J.1471-4159.1994.62062067.X  0.493
1993 Schuldiner S, Liu Y, Edwards RH. Reserpine binding to a vesicular amine transporter expressed in Chinese hamster ovary fibroblasts. The Journal of Biological Chemistry. 268: 29-34. PMID 8416935  0.49
1993 Taglicht D, Padan E, Schuldiner S. Proton-sodium stoichiometry of NhaA, an electrogenic antiporter from Escherichia coli. The Journal of Biological Chemistry. 268: 5382-7. PMID 8383669  0.324
1993 Gerchman Y, Olami Y, Rimon A, Taglicht D, Schuldiner S, Padan E. Histidine-226 is part of the pH sensor of NhaA, a Na+/H+ antiporter in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 90: 1212-6. PMID 8381959 DOI: 10.1073/Pnas.90.4.1212  0.377
1993 Padan E, Schuldiner S. Na+/H+ antiporters, molecular devices that couple the Na+ and H+ circulation in cells. Journal of Bioenergetics and Biomembranes. 25: 647-69. PMID 8144493 DOI: 10.1007/Bf00770252  0.377
1993 Ahmed M, Borsch CM, Neyfakh AA, Schuldiner S. Mutants of the Bacillus subtilis multidrug transporter Bmr with altered sensitivity to the antihypertensive alkaloid reserpine. The Journal of Biological Chemistry. 268: 11086-9. PMID 8098708  0.424
1993 Pinner E, Kotler Y, Padan E, Schuldiner S. Physiological role of nhaB, a specific Na+/H+ antiporter in Escherichia coli. The Journal of Biological Chemistry. 268: 1729-34. PMID 8093613  0.325
1993 Schuldiner S, Steiner-Mordoch S, Yelin R, Wall SC, Rudnick G. Amphetamine derivatives interact with both plasma membrane and secretory vesicle biogenic amine transporters. Molecular Pharmacology. 44: 1227-31. PMID 7903417  0.5
1992 Liu Y, Peter D, Roghani A, Schuldiner S, Privé GG, Eisenberg D, Brecha N, Edwards RH. A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter. Cell. 70: 539-51. PMID 1505023 DOI: 10.1016/0092-8674(92)90425-C  0.521
1992 Suchi R, Stern-Bach Y, Schuldiner S. Modification of arginyl or histidyl groups affects the energy coupling of the amine transporter. Biochemistry. 31: 12500-3. PMID 1463736 DOI: 10.1021/Bi00164A029  0.79
1992 Stern-Bach Y, Keen JN, Bejerano M, Steiner-Mordoch S, Wallach M, Findlay JB, Schuldiner S. Homology of a vesicular amine transporter to a gene conferring resistance to 1-methyl-4-phenylpyridinium. Proceedings of the National Academy of Sciences of the United States of America. 89: 9730-3. PMID 1357668 DOI: 10.1073/Pnas.89.20.9730  0.767
1992 Pinner E, Padan E, Schuldiner S. Cloning, sequencing, and expression of the nhaB gene, encoding a Na+/H+ antiporter in Escherichia coli. The Journal of Biological Chemistry. 267: 11064-8. PMID 1317851  0.35
1992 Pinner E, Carmel O, Bercovier H, Sela S, Padan E, Schuldiner S. Cloning, sequencing and expression of the nhaA and nhaR genes from Salmonella enteritidis. Archives of Microbiology. 157: 323-8. PMID 1317153 DOI: 10.1007/Bf00248676  0.349
1992 Rahav-Manor O, Carmel O, Karpel R, Taglicht D, Glaser G, Schuldiner S, Padan E. NhaR, a protein homologous to a family of bacterial regulatory proteins (LysR), regulates nhaA, the sodium proton antiporter gene in Escherichia coli. The Journal of Biological Chemistry. 267: 10433-8. PMID 1316901  0.304
1991 Suchi R, Stern-Bach Y, Gabay T, Schuldiner S. Covalent modification of the amine transporter with N,N'-dicyclohexylcarbodiimide. Biochemistry. 30: 6490-4. PMID 2054348 DOI: 10.1021/Bi00240A020  0.746
1990 Stern-Bach Y, Greenberg-Ofrath N, Flechner I, Schuldiner S. Identification and purification of a functional amine transporter from bovine chromaffin granules. The Journal of Biological Chemistry. 265: 3961-6. PMID 2303487  0.788
1990 Rudnick G, Steiner-Mordoch SS, Fishkes H, Stern-Bach Y, Schuldiner S. Energetics of reserpine binding and occlusion by the chromaffin granule biogenic amine transporter. Biochemistry. 29: 603-8. PMID 2140052 DOI: 10.1021/Bi00455A002  0.785
1989 Shirvan MH, Schuldiner S, Rottem S. Role of Na+ cycle in cell volume regulation of Mycoplasma gallisepticum. Journal of Bacteriology. 171: 4410-6. PMID 2753860 DOI: 10.1128/Jb.171.8.4410-4416.1989  0.392
1989 Padan E, Maisler N, Taglicht D, Karpel R, Schuldiner S. Deletion of ant in Escherichia coli reveals its function in adaptation to high salinity and an alternative Na+/H+ antiporter system(s). The Journal of Biological Chemistry. 264: 20297-302. PMID 2555351  0.331
1989 Rudnick G, Kirk KL, Fishkes H, Schuldiner S. Zwitterionic and anionic forms of a serotonin analog as transport substrates. The Journal of Biological Chemistry. 264: 14865-8. PMID 2549040  0.429
1989 Shirvan MH, Schuldiner S, Rottem S. Volume regulation in Mycoplasma gallisepticum: evidence that Na+ is extruded via a primary Na+ pump. Journal of Bacteriology. 171: 4417-24. PMID 2526806 DOI: 10.1128/Jb.171.8.4417-4424.1989  0.428
1987 Schuldiner S, Gabizon R, Stern Y, Suchi R. The amine transporter from bovine chromaffin granules: photolabeling and partial purification. Annals of the New York Academy of Sciences. 493: 189-93. PMID 3473960 DOI: 10.1111/J.1749-6632.1987.Tb27200.X  0.543
1987 Padan E, Schuldiner S. Intracellular pH and membrane potential as regulators in the prokaryotic cell. The Journal of Membrane Biology. 95: 189-98. PMID 3295250 DOI: 10.1007/Bf01869481  0.345
1987 Goldberg EB, Arbel T, Chen J, Karpel R, Mackie GA, Schuldiner S, Padan E. Characterization of a Na+/H+ antiporter gene of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 84: 2615-9. PMID 3033655 DOI: 10.1073/Pnas.84.9.2615  0.32
1986 Padan E, Schuldiner S. Intracellular pH regulation in bacterial cells. Methods in Enzymology. 125: 337-52. PMID 3713535 DOI: 10.1016/S0076-6879(86)25029-6  0.363
1986 Schuldiner S, Agmon V, Brandsma J, Cohen A, Friedman E, Padan E. Induction of SOS functions by alkaline intracellular pH in Escherichia coli. Journal of Bacteriology. 168: 936-9. PMID 3096964 DOI: 10.1128/Jb.168.2.936-939.1986  0.342
1985 Gabizon R, Schuldiner S. The amine transporter from bovine chromaffin granules. Partial purification. The Journal of Biological Chemistry. 260: 3001-5. PMID 3972813  0.461
1985 Schuldiner S, Gabizon R, Maron R, Suchi R, Stern Y. The amine transporter from bovine chromaffin granules. Annals of the New York Academy of Sciences. 456: 268-76. PMID 2868685 DOI: 10.1111/J.1749-6632.1985.Tb14875.X  0.532
1984 Zilberstein D, Agmon V, Schuldiner S, Padan E. Escherichia coli intracellular pH, membrane potential, and cell growth. Journal of Bacteriology. 158: 246-52. PMID 6325389 DOI: 10.1128/Jb.158.1.246-252.1984  0.351
1983 Maron R, Stern Y, Kanner BI, Schuldiner S. Functional asymmetry of the amine transporter from chromaffin granules. The Journal of Biological Chemistry. 258: 11476-81. PMID 6311813  0.398
1982 Gabizon R, Yetinson T, Schuldiner S. Photoinactivation and identification of the biogenic amine transporter in chromaffin granules from bovine adrenal medulla. The Journal of Biological Chemistry. 257: 15145-50. PMID 7174689  0.455
1982 Schuldiner S, Rozengurt E. Na+/H+ antiport in Swiss 3T3 cells: mitogenic stimulation leads to cytoplasmic alkalinization. Proceedings of the National Academy of Sciences of the United States of America. 79: 7778-82. PMID 6961450 DOI: 10.1073/Pnas.79.24.7778  0.355
1980 Rudnick G, Fishkes H, Nelson PJ, Schuldiner S. Evidence for two distinct serotonin transport systems in platelets. The Journal of Biological Chemistry. 255: 3638-41. PMID 7364762  0.413
1980 Kanner BI, Sharon I, Maron R, Schuldiner S. Electrogenic transport of biogenic amines in chromaffin granule membrane vesicles. Febs Letters. 111: 83-6. PMID 7358168 DOI: 10.1016/0014-5793(80)80766-6  0.475
1980 Zilberstein D, Padan E, Schuldiner S. A single locus in Escherichia coli governs growth in alkaline pH and on carbon sources whose transport is sodium dependent. Febs Letters. 116: 177-80. PMID 6997070 DOI: 10.1016/0014-5793(80)80637-5  0.374
1980 Schuldiner S, Maron R, Kanner BI. Active transport of biogenic amines in chromaffin granule membrane vesicles. Monographs in Neural Sciences. 7: 117-28. PMID 6453280 DOI: 10.1159/000388819  0.531
1980 Kanner BI, Sharon I, Maron R, Schuldiner S. Electrogenic transport of biogenic amines in chromaffin granule membrane vesicle (1980) FEBS Letters 111, 83-86 Febs Letters. 115: 325. DOI: 10.1016/0014-5793(80)81199-9  0.475
1979 Kanner BI, Fishkes H, Maron R, Sharon I, Schuldiner S. Reserpine as a competitive and reversible inhibitor of the catecholamine transporter of bovine chromaffin granules. Febs Letters. 100: 175-8. PMID 437101 DOI: 10.1016/0014-5793(79)81158-8  0.486
1979 Maron R, Fishkes H, Kanner BI, Schuldiner S. Solubilization and reconstitution of the catecholamine transporter from bovine chromaffin granules. Biochemistry. 18: 4781-5. PMID 41569 DOI: 10.1021/Bi00589A003  0.529
1979 Ramos S, Schuldiner S, Kaback HR. The use of flow dialysis for determinations of deltapH and active transport. Methods in Enzymology. 55: 680-8. PMID 37407 DOI: 10.1016/0076-6879(79)55076-9  0.4
1979 Maron R, Kanner BI, Schuldiner S. The role of a transmembrane pH gradient in 5-hydroxy tryptamine uptake by synaptic vesicles from rat brain. Febs Letters. 98: 237-40. PMID 33834 DOI: 10.1016/0014-5793(79)80190-8  0.309
1979 Zilberstein D, Schuldiner S, Padan E. Proton electrochemical gradient in Escherichia coli cells and its relation to active transport of lactose. Biochemistry. 18: 669-73. PMID 33700 DOI: 10.1021/Bi00571A018  0.494
1978 Schuldiner S, Fishkes H, Kanner BI. Role of a transmembrane pH gradient in epinephrine transport by chromaffin granule membrane vesicles. Proceedings of the National Academy of Sciences of the United States of America. 75: 3713-6. PMID 29292 DOI: 10.1073/Pnas.75.8.3713  0.518
1978 Schuldiner S, Fishkes H. Sodium-proton antiport in isolated membrane vesicles of Escherichia coli. Biochemistry. 17: 706-11. PMID 23828 DOI: 10.1021/Bi00597A023  0.362
1977 Schuldiner S, Weil R, Robertson DE, Kaback HR. Microenvironment of the binding site in the lac carrier protein. Proceedings of the National Academy of Sciences of the United States of America. 74: 1851-4. PMID 325557 DOI: 10.1073/Pnas.74.5.1851  0.338
1976 Rudnick G, Schuldiner S, Kaback HR. Equilibrium between two forms of the lac carrier protein in energized and nonenergized membrane vesicles from Escherichia coli Biochemistry. 15: 5126-5131. PMID 791364 DOI: 10.1021/bi00668a028  0.322
1976 Schuldiner S, Weil R, Kaback HR. Energy-dependent binding of dansylgalactoside to the lac carrier protein: direct binding measurements. Proceedings of the National Academy of Sciences of the United States of America. 73: 109-12. PMID 174094 DOI: 10.1073/Pnas.73.1.109  0.415
1976 Ramos S, Schuldiner S, Kaback HR. The electrochemical gradient of protons and its relationship to active transport in Escherichia coli membrane vesicles. Proceedings of the National Academy of Sciences of the United States of America. 73: 1892-6. PMID 6961 DOI: 10.1073/Pnas.73.6.1892  0.464
1976 Schuldiner S, Rudnick G, Weil R, Kaback HR. Mechanism of β galactoside transport in Escherichia coli membrane vesicles Trends Biochem.Sci.. 1: 41-45. DOI: 10.1016/S0968-0004(76)80181-8  0.436
1976 Schuldiner S, Rudnick G, Weil R, Kaback HR. Mechanism of β-galactoside transport in Escherichia coli membrane vesicles Trends in Biochemical Sciences. 1: 41-45. DOI: 10.1016/S0968-0004(76)80181-8  0.332
1975 Kaback HR, Rudnick G, Schuldiner S, Short SA. Active transport in isolated bacterial membrane vesicles: binding of beta-galactosides to the LAC carrier protein. Annals of the New York Academy of Sciences. 264: 350-7. PMID 769642 DOI: 10.1111/j.1749-6632.1975.tb31495.x  0.376
1975 Schuldiner S, Kaback HR. Membrane potential and active transport in membrane vesicles from Escherichia coli. Biochemistry. 14: 5451-61. PMID 172125 DOI: 10.1021/bi00696a011  0.318
1975 Patel L, Schuldiner S, Kaback HR. Reversible effects of chaotropic agents on the proton permeability of Escherichia coli membrane vesicles. Proceedings of the National Academy of Sciences of the United States of America. 72: 3387-91. PMID 171661 DOI: 10.1073/Pnas.72.9.3387  0.435
1974 Schuldiner S, Padan E, Rottenberg H, Gromet-Elhanan Z, Avron M. Delta pH and membrane potential in bacterial chromatophores. Febs Letters. 49: 174-7. PMID 4216516 DOI: 10.1016/0014-5793(74)80505-3  0.338
1973 Schuldiner S, Rottenberg H, Avron M. Stimulation of ATP synthesis by a membrane potential in chloroplasts. European Journal of Biochemistry / Febs. 39: 455-62. PMID 4129992 DOI: 10.1111/J.1432-1033.1973.Tb03144.X  0.363
1971 Schuldiner S, Avron M. On the mechanism of the energy-dependent quenching of atebrin fluorescence in isolated chloroplasts. Febs Letters. 14: 233-236. PMID 11945766 DOI: 10.1016/0014-5793(71)80625-7  0.33
1971 Schuldiner S, Avron M. Anion permeability of chloroplasts. European Journal of Biochemistry / Febs. 19: 227-31. PMID 5552391 DOI: 10.1111/J.1432-1033.1971.Tb01308.X  0.332
1971 Walz D, Schuldiner S, Avron M. Photoreactions of chloroplasts in a glycine medium. European Journal of Biochemistry / Febs. 22: 439-44. PMID 5132193 DOI: 10.1111/J.1432-1033.1971.Tb01562.X  0.334
1969 Schuldiner S, Ohad I. Biogenesis of chloroplast membranes. 3. Light-dependent induction of proton pump activity in whole cells and its correlation to cytochrome f photooxidation during greening of a Chlamydomonas reinhardti mutant (y-I). Biochimica Et Biophysica Acta. 180: 165-77. PMID 5787264 DOI: 10.1016/0005-2728(69)90203-5  0.33
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