Year |
Citation |
Score |
2020 |
Reyes-Fernández EZ, Schuldiner S. Acidification of Cytoplasm in Escherichia coli Provides a Strategy to Cope with Stress and Facilitates Development of Antibiotic Resistance. Scientific Reports. 10: 9954. PMID 32561799 DOI: 10.1038/S41598-020-66890-1 |
0.338 |
|
2019 |
Alon Cudkowicz N, Schuldiner S. Deletion of the major Escherichia coli multidrug transporter AcrB reveals transporter plasticity and redundancy in bacterial cells. Plos One. 14: e0218828. PMID 31251753 DOI: 10.1371/Journal.Pone.0218828 |
0.509 |
|
2018 |
Yaffe D, Forrest LR, Schuldiner S. The ins and outs of vesicular monoamine transporters. The Journal of General Physiology. PMID 29666153 DOI: 10.1085/Jgp.201711980 |
0.541 |
|
2018 |
Schuldiner S. The Escherichia coli effluxome. Research in Microbiology. PMID 29574104 DOI: 10.1016/J.Resmic.2018.02.006 |
0.536 |
|
2016 |
Yaffe D, Vergara-Jaque A, Forrest LR, Schuldiner S. Emulating proton-induced conformational changes in the vesicular monoamine transporter VMAT2 by mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27821772 DOI: 10.1073/Pnas.1605162113 |
0.521 |
|
2016 |
Shuster Y, Steiner-Mordoch S, Alon Cudkowicz N, Schuldiner S. A Transporter Interactome Is Essential for the Acquisition of Antimicrobial Resistance to Antibiotics. Plos One. 11: e0152917. PMID 27050393 DOI: 10.1371/Journal.Pone.0152917 |
0.475 |
|
2015 |
Melchior DL, Brill S, Wright GE, Schuldiner S. A liposomal method for evaluation of inhibitors of H(+)-coupled multidrug transporters. Journal of Pharmacological and Toxicological Methods. 77: 53-57. PMID 26463179 DOI: 10.1016/J.Vascn.2015.09.007 |
0.514 |
|
2015 |
Brill S, Sade-Falk O, Elbaz-Alon Y, Schuldiner S. Specificity determinants in small multidrug transporters. Journal of Molecular Biology. 427: 468-77. PMID 25479374 DOI: 10.1016/J.Jmb.2014.11.015 |
0.52 |
|
2015 |
Vergara-Jaque A, Yaffe D, Shuster Y, Listov D, Meena S, Singh SK, Schuldiner S, Forrest LR. Carboxyl Residues Required for Transport by a Vesicular Monoamine Transporter Homolog from Brevibacillus Brevis (BbMAT) Biophysical Journal. 108: 462a. DOI: 10.1016/J.Bpj.2014.11.2522 |
0.571 |
|
2014 |
Yaffe D, Vergara-Jaque A, Shuster Y, Listov D, Meena S, Singh SK, Forrest LR, Schuldiner S. Functionally important carboxyls in a bacterial homologue of the vesicular monoamine transporter (VMAT). The Journal of Biological Chemistry. 289: 34229-40. PMID 25336661 DOI: 10.1074/Jbc.M114.607366 |
0.576 |
|
2014 |
Schuldiner S. Competition as a way of life for H(+)-coupled antiporters. Journal of Molecular Biology. 426: 2539-46. PMID 24862284 DOI: 10.1016/J.Jmb.2014.05.020 |
0.486 |
|
2014 |
Lohr C, Christensen AL, Veshaguri S, Tutkus M, Iversen L, Kemmer G, Yaffe D, Zollmann T, Curran P, Schuldiner S, Tampé R, Pomorski T, Mindell J, Stamou D. Single Liposomes Used to Study the Activity of Individual Transporters Biophysical Journal. 106: 229a. DOI: 10.1016/J.Bpj.2013.11.1339 |
0.401 |
|
2013 |
Ugolev Y, Segal T, Yaffe D, Gros Y, Schuldiner S. Identification of conformationally sensitive residues essential for inhibition of vesicular monoamine transport by the noncompetitive inhibitor tetrabenazine. The Journal of Biological Chemistry. 288: 32160-71. PMID 24062308 DOI: 10.1074/Jbc.M113.502971 |
0.564 |
|
2013 |
Nasie I, Steiner-Mordoch S, Schuldiner S. Topology determination of untagged membrane proteins. Methods in Molecular Biology (Clifton, N.J.). 1033: 121-30. PMID 23996174 DOI: 10.1007/978-1-62703-487-6_8 |
0.335 |
|
2013 |
Yaffe D, Radestock S, Shuster Y, Forrest LR, Schuldiner S. Identification of molecular hinge points mediating alternating access in the vesicular monoamine transporter VMAT2. Proceedings of the National Academy of Sciences of the United States of America. 110: E1332-41. PMID 23530208 DOI: 10.1073/Pnas.1220497110 |
0.532 |
|
2012 |
Nasie I, Steiner-Mordoch S, Schuldiner S. New substrates on the block: clinically relevant resistances for EmrE and homologues. Journal of Bacteriology. 194: 6766-70. PMID 23042996 DOI: 10.1128/Jb.01318-12 |
0.444 |
|
2012 |
Brill S, Falk OS, Schuldiner S. Transforming a drug/H+ antiporter into a polyamine importer by a single mutation. Proceedings of the National Academy of Sciences of the United States of America. 109: 16894-9. PMID 23035252 DOI: 10.1073/Pnas.1211831109 |
0.427 |
|
2012 |
Schuldiner S. Undecided membrane proteins insert in random topologies. Up, down and sideways: it does not really matter. Trends in Biochemical Sciences. 37: 215-9. PMID 22444835 DOI: 10.1016/J.Tibs.2012.02.006 |
0.4 |
|
2010 |
Elbaz Y, Danieli T, Kanner BI, Schuldiner S. Expression of neurotransmitter transporters for structural and biochemical studies. Protein Expression and Purification. 73: 152-60. PMID 20566324 DOI: 10.1016/J.Pep.2010.06.001 |
0.516 |
|
2010 |
Nasie I, Steiner-Mordoch S, Gold A, Schuldiner S. Topologically random insertion of EmrE supports a pathway for evolution of inverted repeats in ion-coupled transporters. The Journal of Biological Chemistry. 285: 15234-44. PMID 20308069 DOI: 10.1074/Jbc.M110.108746 |
0.534 |
|
2010 |
Gros Y, Schuldiner S. Directed evolution reveals hidden properties of VMAT, a neurotransmitter transporter. The Journal of Biological Chemistry. 285: 5076-84. PMID 20007701 DOI: 10.1074/Jbc.M109.081216 |
0.529 |
|
2009 |
Miller D, Charalambous K, Rotem D, Schuldiner S, Curnow P, Booth PJ. In vitro unfolding and refolding of the small multidrug transporter EmrE. Journal of Molecular Biology. 393: 815-32. PMID 19699749 DOI: 10.1016/J.Jmb.2009.08.039 |
0.397 |
|
2009 |
Tal N, Schuldiner S. A coordinated network of transporters with overlapping specificities provides a robust survival strategy. Proceedings of the National Academy of Sciences of the United States of America. 106: 9051-6. PMID 19451626 DOI: 10.1073/Pnas.0902400106 |
0.516 |
|
2009 |
Schuldiner S. EmrE, a model for studying evolution and mechanism of ion-coupled transporters. Biochimica Et Biophysica Acta. 1794: 748-62. PMID 19167526 DOI: 10.1016/J.Bbapap.2008.12.018 |
0.53 |
|
2008 |
Elbaz Y, Salomon T, Schuldiner S. Identification of a glycine motif required for packing in EmrE, a multidrug transporter from Escherichia coli. The Journal of Biological Chemistry. 283: 12276-83. PMID 18321856 DOI: 10.1074/Jbc.M710338200 |
0.528 |
|
2008 |
Adam Y, Edwards RH, Schuldiner S. Expression and function of the rat vesicular monoamine transporter 2. American Journal of Physiology. Cell Physiology. 294: C1004-11. PMID 18287335 DOI: 10.1152/Ajpcell.00348.2007 |
0.798 |
|
2008 |
Steiner-Mordoch S, Soskine M, Solomon D, Rotem D, Gold A, Yechieli M, Adam Y, Schuldiner S. Parallel topology of genetically fused EmrE homodimers. The Embo Journal. 27: 17-26. PMID 18059473 DOI: 10.1038/Sj.Emboj.7601951 |
0.789 |
|
2007 |
Adam Y, Tayer N, Rotem D, Schreiber G, Schuldiner S. The fast release of sticky protons: kinetics of substrate binding and proton release in a multidrug transporter. Proceedings of the National Academy of Sciences of the United States of America. 104: 17989-94. PMID 17984053 DOI: 10.1073/Pnas.0704425104 |
0.762 |
|
2007 |
Agarwal V, Fink U, Schuldiner S, Reif B. MAS solid-state NMR studies on the multidrug transporter EmrE. Biochimica Et Biophysica Acta. 1768: 3036-43. PMID 17976529 DOI: 10.1016/J.Bbamem.2007.09.012 |
0.418 |
|
2007 |
Schuldiner S. Controversy over EmrE structure. Science (New York, N.Y.). 317: 748-51; author reply. PMID 17690276 DOI: 10.1126/Science.317.5839.748D |
0.377 |
|
2007 |
Schuldiner S. When biochemistry meets structural biology: the cautionary tale of EmrE. Trends in Biochemical Sciences. 32: 252-8. PMID 17452106 DOI: 10.1016/J.Tibs.2007.04.002 |
0.398 |
|
2006 |
Soskine M, Mark S, Tayer N, Mizrachi R, Schuldiner S. On parallel and antiparallel topology of a homodimeric multidrug transporter. The Journal of Biological Chemistry. 281: 36205-12. PMID 17003034 DOI: 10.1074/Jbc.M607186200 |
0.423 |
|
2006 |
Schuldiner S. Structural biology: the ins and outs of drug transport. Nature. 443: 156-7. PMID 16971936 DOI: 10.1038/443156B |
0.476 |
|
2006 |
Rotem D, Steiner-Mordoch S, Schuldiner S. Identification of tyrosine residues critical for the function of an ion-coupled multidrug transporter. The Journal of Biological Chemistry. 281: 18715-22. PMID 16672221 DOI: 10.1074/Jbc.M602088200 |
0.564 |
|
2005 |
Sigal N, Vardy E, Molshanski-Mor S, Eitan A, Pilpel Y, Schuldiner S, Bibi E. 3D model of the Escherichia coli multidrug transporter MdfA reveals an essential membrane-embedded positive charge. Biochemistry. 44: 14870-80. PMID 16274234 DOI: 10.1021/Bi051574P |
0.382 |
|
2005 |
Vardy E, Steiner-Mordoch S, Schuldiner S. Characterization of bacterial drug antiporters homologous to mammalian neurotransmitter transporters. Journal of Bacteriology. 187: 7518-25. PMID 16237035 DOI: 10.1128/Jb.187.21.7518-7525.2005 |
0.498 |
|
2005 |
Sharoni M, Steiner-Mordoch S, Schuldiner S. Exploring the binding domain of EmrE, the smallest multidrug transporter. The Journal of Biological Chemistry. 280: 32849-55. PMID 16049002 DOI: 10.1074/Jbc.M504910200 |
0.475 |
|
2005 |
Elbaz Y, Tayer N, Steinfels E, Steiner-Mordoch S, Schuldiner S. Substrate-induced tryptophan fluorescence changes in EmrE, the smallest ion-coupled multidrug transporter. Biochemistry. 44: 7369-77. PMID 15882076 DOI: 10.1021/Bi050356T |
0.484 |
|
2005 |
Weinglass AB, Soskine M, Vazquez-Ibar JL, Whitelegge JP, Faull KF, Kaback HR, Schuldiner S. Exploring the role of a unique carboxyl residue in EmrE by mass spectrometry. The Journal of Biological Chemistry. 280: 7487-92. PMID 15623511 DOI: 10.1074/Jbc.M413555200 |
0.424 |
|
2004 |
Rotem D, Schuldiner S. EmrE, a multidrug transporter from Escherichia coli, transports monovalent and divalent substrates with the same stoichiometry. The Journal of Biological Chemistry. 279: 48787-93. PMID 15371426 DOI: 10.1074/Jbc.M408187200 |
0.555 |
|
2004 |
Vardy E, Arkin IT, Gottschalk KE, Kaback HR, Schuldiner S. Structural conservation in the major facilitator superfamily as revealed by comparative modeling. Protein Science : a Publication of the Protein Society. 13: 1832-40. PMID 15215526 DOI: 10.1110/Ps.04657704 |
0.465 |
|
2004 |
Gottschalk KE, Soskine M, Schuldiner S, Kessler H. A structural model of EmrE, a multi-drug transporter from Escherichia coli. Biophysical Journal. 86: 3335-48. PMID 15189838 DOI: 10.1529/Biophysj.103.034546 |
0.498 |
|
2004 |
Ninio S, Elbaz Y, Schuldiner S. The membrane topology of EmrE - a small multidrug transporter from Escherichia coli. Febs Letters. 562: 193-6. PMID 15044024 DOI: 10.1016/S0014-5793(04)00240-6 |
0.481 |
|
2004 |
Elbaz Y, Steiner-Mordoch S, Danieli T, Schuldiner S. In vitro synthesis of fully functional EmrE, a multidrug transporter, and study of its oligomeric state. Proceedings of the National Academy of Sciences of the United States of America. 101: 1519-24. PMID 14755055 DOI: 10.1073/Pnas.0306533101 |
0.519 |
|
2004 |
Soskine M, Adam Y, Schuldiner S. Direct evidence for substrate-induced proton release in detergent-solubilized EmrE, a multidrug transporter. The Journal of Biological Chemistry. 279: 9951-5. PMID 14701800 DOI: 10.1074/Jbc.M312853200 |
0.776 |
|
2003 |
Ubarretxena-Belandia I, Baldwin JM, Schuldiner S, Tate CG. Three-dimensional structure of the bacterial multidrug transporter EmrE shows it is an asymmetric homodimer. The Embo Journal. 22: 6175-81. PMID 14633977 DOI: 10.1093/Emboj/Cdg611 |
0.457 |
|
2003 |
Gutman N, Steiner-Mordoch S, Schuldiner S. An amino acid cluster around the essential Glu-14 is part of the substrate- and proton-binding domain of EmrE, a multidrug transporter from Escherichia coli. The Journal of Biological Chemistry. 278: 16082-7. PMID 12590142 DOI: 10.1074/Jbc.M213120200 |
0.494 |
|
2003 |
Ninio S, Schuldiner S. Characterization of an archaeal multidrug transporter with a unique amino acid composition. The Journal of Biological Chemistry. 278: 12000-5. PMID 12551892 DOI: 10.1074/Jbc.M213119200 |
0.483 |
|
2002 |
Soskine M, Steiner-Mordoch S, Schuldiner S. Crosslinking of membrane-embedded cysteines reveals contact points in the EmrE oligomer. Proceedings of the National Academy of Sciences of the United States of America. 99: 12043-8. PMID 12221291 DOI: 10.1073/Pnas.192392899 |
0.4 |
|
2001 |
Ninio S, Rotem D, Schuldiner S. Functional analysis of novel multidrug transporters from human pathogens. The Journal of Biological Chemistry. 276: 48250-6. PMID 11574548 DOI: 10.1074/Jbc.M108231200 |
0.499 |
|
2001 |
Rotem D, Sal-man N, Schuldiner S. In vitro monomer swapping in EmrE, a multidrug transporter from Escherichia coli, reveals that the oligomer is the functional unit. The Journal of Biological Chemistry. 276: 48243-9. PMID 11572877 DOI: 10.1074/Jbc.M108229200 |
0.507 |
|
2001 |
Schuldiner S, Granot D, Mordoch SS, Ninio S, Rotem D, Soskin M, Tate CG, Yerushalmi H. Small is mighty: EmrE, a multidrug transporter as an experimental paradigm. News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 16: 130-4. PMID 11443233 |
0.453 |
|
2001 |
Yelin R, Schuldiner S. Vesicular monoamine transporters heterologously expressed in the yeast Saccharomyces cerevisiae display high-affinity tetrabenazine binding. Biochimica Et Biophysica Acta. 1510: 426-41. PMID 11342177 DOI: 10.1016/S0005-2736(00)00374-6 |
0.498 |
|
2001 |
Schuldiner S, Granot D, Steiner S, Ninio S, Rotem D, Soskin M, Yerushalmi H. Precious things come in little packages. Journal of Molecular Microbiology and Biotechnology. 3: 155-62. PMID 11321568 |
0.493 |
|
2001 |
Yerushalmi H, Mordoch SS, Schuldiner S. A single carboxyl mutant of the multidrug transporter EmrE is fully functional. The Journal of Biological Chemistry. 276: 12744-8. PMID 11278804 DOI: 10.1074/Jbc.M010979200 |
0.529 |
|
2001 |
Tate CG, Kunji ER, Lebendiker M, Schuldiner S. The projection structure of EmrE, a proton-linked multidrug transporter from Escherichia coli, at 7 A resolution. The Embo Journal. 20: 77-81. PMID 11226157 DOI: 10.1093/Emboj/20.1.77 |
0.411 |
|
2000 |
Yerushalmi H, Schuldiner S. A model for coupling of H(+) and substrate fluxes based on "time-sharing" of a common binding site. Biochemistry. 39: 14711-9. PMID 11101285 DOI: 10.1021/Bi001892I |
0.544 |
|
2000 |
Glaubitz C, Gröger A, Gottschalk K, Spooner P, Watts A, Schuldiner S, Kessler H. 31P-CP-MAS NMR studies on TPP+ bound to the ion-coupled multidrug transport protein EmrE. Febs Letters. 480: 127-31. PMID 11034313 DOI: 10.1016/S0014-5793(00)01916-5 |
0.431 |
|
2000 |
Yerushalmi H, Schuldiner S. A common binding site for substrates and protons in EmrE, an ion-coupled multidrug transporter. Febs Letters. 476: 93-7. PMID 10878258 DOI: 10.1042/Bst028A143A |
0.534 |
|
2000 |
Yerushalmi H, Schuldiner S. An essential glutamyl residue in EmrE, a multidrug antiporter from Escherichia coli. The Journal of Biological Chemistry. 275: 5264-9. PMID 10681497 DOI: 10.1074/Jbc.275.8.5264 |
0.514 |
|
2000 |
Muth TR, Schuldiner S. A membrane-embedded glutamate is required for ligand binding to the multidrug transporter EmrE. The Embo Journal. 19: 234-40. PMID 10637227 DOI: 10.1093/Emboj/19.2.234 |
0.506 |
|
1999 |
Williams KA, Geldmacher-Kaufer U, Padan E, Schuldiner S, Kühlbrandt W. Projection structure of NhaA, a secondary transporter from Escherichia coli, at 4.0 A resolution. The Embo Journal. 18: 3558-63. PMID 10393172 DOI: 10.1093/Emboj/18.13.3558 |
0.395 |
|
1999 |
Mordoch SS, Granot D, Lebendiker M, Schuldiner S. Scanning cysteine accessibility of EmrE, an H+-coupled multidrug transporter from Escherichia coli, reveals a hydrophobic pathway for solutes. The Journal of Biological Chemistry. 274: 19480-6. PMID 10383465 DOI: 10.1074/Jbc.274.27.19480 |
0.494 |
|
1999 |
Yelin R, Rotem D, Schuldiner S. EmrE, a small Escherichia coli multidrug transporter, protects Saccharomyces cerevisiae from toxins by sequestration in the vacuole. Journal of Bacteriology. 181: 949-56. PMID 9922260 DOI: 10.1128/Jb.181.3.949-956.1999 |
0.457 |
|
1998 |
Yelin R, Steiner-Mordoch S, Aroeti B, Schuldiner S. Glycosylation of a vesicular monoamine transporter: a mutation in a conserved proline residue affects the activity, glycosylation, and localization of the transporter. Journal of Neurochemistry. 71: 2518-27. PMID 9832151 DOI: 10.1046/J.1471-4159.1998.71062518.X |
0.488 |
|
1998 |
Yelin R, Schuldiner S. Purification of vesicular monoamine transporters: from classical techniques to histidine tags. Methods in Enzymology. 296: 64-72. PMID 9779440 DOI: 10.1016/S0076-6879(98)96006-2 |
0.575 |
|
1998 |
Schwaiger M, Lebendiker M, Yerushalmi H, Coles M, Gröger A, Schwarz C, Schuldiner S, Kessler H. NMR investigation of the multidrug transporter EmrE, an integral membrane protein. European Journal of Biochemistry / Febs. 254: 610-9. PMID 9688273 DOI: 10.1046/J.1432-1327.1998.2540610.X |
0.467 |
|
1998 |
Schuldiner S, Steiner-Mordoch S, Yelin R. Molecular and biochemical studies of rat vesicular monoamine transporter. Advances in Pharmacology (San Diego, Calif.). 42: 223-7. PMID 9327884 DOI: 10.1016/S1054-3589(08)60733-4 |
0.586 |
|
1997 |
Rothman A, Gerchman Y, Padan E, Schuldiner S. Probing the conformation of NhaA, a Na+/H+ antiporter from Escherichia coli, with trypsin. Biochemistry. 36: 14572-6. PMID 9398175 DOI: 10.1021/Bi971800Y |
0.36 |
|
1997 |
Klyachko KA, Schuldiner S, Neyfakh AA. Mutations affecting substrate specificity of the Bacillus subtilis multidrug transporter Bmr. Journal of Bacteriology. 179: 2189-93. PMID 9079903 |
0.449 |
|
1997 |
Schuldiner S, Lebendiker M, Yerushalmi H. EmrE, the smallest ion-coupled transporter, provides a unique paradigm for structure-function studies. The Journal of Experimental Biology. 200: 335-41. PMID 9050242 |
0.406 |
|
1997 |
Yelin R, Mordoch S, Schuldiner S. The role of glycosylation in the vesicular monoamine transporter Neuroscience Letters. 237: S53. DOI: 10.1016/S0304-3940(97)90219-6 |
0.51 |
|
1996 |
Rothman A, Padan E, Schuldiner S. Topological analysis of NhaA, a Na+/H+ antiporter from Escherichia coli. The Journal of Biological Chemistry. 271: 32288-92. PMID 8943289 DOI: 10.1074/Jbc.271.50.32288 |
0.352 |
|
1996 |
Yerushalmi H, Lebendiker M, Schuldiner S. Negative dominance studies demonstrate the oligomeric structure of EmrE, a multidrug antiporter from Escherichia coli. The Journal of Biological Chemistry. 271: 31044-8. PMID 8940098 DOI: 10.1074/Jbc.271.49.31044 |
0.475 |
|
1996 |
Lebendiker M, Schuldiner S. Identification of residues in the translocation pathway of EmrE, a multidrug antiporter from Escherichia coli. The Journal of Biological Chemistry. 271: 21193-9. PMID 8702890 DOI: 10.1074/Jbc.271.35.21193 |
0.509 |
|
1996 |
Arkin IT, Russ WP, Lebendiker M, Schuldiner S. Determining the secondary structure and orientation of EmrE, a multi-drug transporter, indicates a transmembrane four-helix bundle. Biochemistry. 35: 7233-8. PMID 8679552 DOI: 10.1021/Bi960094I |
0.391 |
|
1996 |
Steiner-Mordoch S, Shirvan A, Schuldiner S. Modification of the pH profile and tetrabenazine sensitivity of rat VMAT1 by replacement of aspartate 404 with glutamate. The Journal of Biological Chemistry. 271: 13048-54. PMID 8662678 DOI: 10.1074/Jbc.271.22.13048 |
0.557 |
|
1996 |
Schuldiner S, Lebendiker M, Mordoch S, Yelin R, Yerushalmi H. Chapter 18 From multidrug resistance to vesicular neurotransmitter transport Handbook of Biological Physics. 2: 405-431. DOI: 10.1016/S1383-8121(96)80059-5 |
0.374 |
|
1995 |
Yelin R, Schuldiner S. The pharmacological profile of the vesicular monoamine transporter resembles that of multidrug transporters. Febs Letters. 377: 201-7. PMID 8543051 DOI: 10.1016/0014-5793(95)01346-6 |
0.575 |
|
1995 |
Yerushalmi H, Lebendiker M, Schuldiner S. EmrE, an Escherichia coli 12-kDa multidrug transporter, exchanges toxic cations and H+ and is soluble in organic solvents. The Journal of Biological Chemistry. 270: 6856-63. PMID 7896833 DOI: 10.1074/Jbc.270.12.6856 |
0.556 |
|
1995 |
Harel-Bronstein M, Dibrov P, Olami Y, Pinner E, Schuldiner S, Padan E. MH1, a second-site revertant of an Escherichia coli mutant lacking Na+/H+ antiporters (delta nhaA delta nhaB), regains Na+ resistance and a capacity to excrete Na+ in a delta microH(+)-independent fashion. The Journal of Biological Chemistry. 270: 3816-22. PMID 7876124 DOI: 10.1074/Jbc.270.8.3816 |
0.368 |
|
1995 |
Pinner E, Padan E, Schuldiner S. Amiloride and harmaline are potent inhibitors of NhaB, a Na+/H+ antiporter from Escherichia coli. Febs Letters. 365: 18-22. PMID 7774707 DOI: 10.1016/0014-5793(95)00364-F |
0.406 |
|
1995 |
Schuldiner S, Shirvan A, Linial M. Vesicular neurotransmitter transporters: from bacteria to humans. Physiological Reviews. 75: 369-92. PMID 7724667 DOI: 10.1152/Physrev.1995.75.2.369 |
0.474 |
|
1995 |
Rimon A, Gerchman Y, Olami Y, Schuldiner S, Padan E. Replacements of histidine 226 of NhaA-Na+/H+ antiporter of Escherichia coli. Cysteine (H226C) or serine (H226S) retain both normal activity and pH sensitivity, aspartate (H226D) shifts the pH profile toward basic pH, and alanine (H226A) inactivates the carrier at all pH values. The Journal of Biological Chemistry. 270: 26813-7. PMID 7592922 DOI: 10.1074/Jbc.270.45.26813 |
0.337 |
|
1994 |
Howell M, Shirvan A, Stern-Bach Y, Steiner-Mordoch S, Strasser JE, Dean GE, Schuldiner S. Cloning and functional expression of a tetrabenazine sensitive vesicular monoamine transporter from bovine chromaffin granules. Febs Letters. 338: 16-22. PMID 8307150 DOI: 10.1016/0014-5793(94)80108-8 |
0.766 |
|
1994 |
Carmel O, Dover N, Rahav-Manor O, Dibrov P, Kirsch D, Karpel R, Schuldiner S, Padan E. A single amino acid substitution (Glu134-->Ala) in NhaR1 increases the inducibility by Na+ of the product of nhaA, a Na+/H+ antiporter gene in Escherichia coli. The Embo Journal. 13: 1981-9. PMID 8168494 DOI: 10.1002/J.1460-2075.1994.Tb06467.X |
0.374 |
|
1994 |
Padan E, Schuldiner S. Molecular physiology of Na+/H+ antiporters, key transporters in circulation of Na+ and H+ in cells. Biochimica Et Biophysica Acta. 1185: 129-51. PMID 8167133 DOI: 10.1016/0005-2728(94)90204-6 |
0.428 |
|
1994 |
Padan E, Schuldiner S. Molecular biology of Na+/H+ antiporters: molecular devices that couple the Na+ and H+ circulation in cells. Biochimica Et Biophysica Acta. 1187: 206-10. PMID 8075114 DOI: 10.1016/0005-2728(94)90112-0 |
0.319 |
|
1994 |
Shirvan A, Laskar O, Steiner-Mordoch S, Schuldiner S. Histidine-419 plays a role in energy coupling in the vesicular monoamine transporter from rat. Febs Letters. 356: 145-50. PMID 7988710 DOI: 10.1016/0014-5793(94)01252-0 |
0.524 |
|
1994 |
Schuldiner S, Shirvan A, Stern-Bach Y, Steiner-Mordoch S, Yelin R, Laskar O. From bacterial antibiotic resistance to neurotransmitter uptake. A common theme of cell survival. Annals of the New York Academy of Sciences. 733: 174-84. PMID 7978865 DOI: 10.1111/J.1749-6632.1994.Tb17267.X |
0.696 |
|
1994 |
Pinner E, Padan E, Schuldiner S. Kinetic properties of NhaB, a Na+/H+ antiporter from Escherichia coli. The Journal of Biological Chemistry. 269: 26274-9. PMID 7929345 |
0.348 |
|
1994 |
Schuldiner S. A molecular glimpse of vesicular monoamine transporters. Journal of Neurochemistry. 62: 2067-78. PMID 7910628 DOI: 10.1046/J.1471-4159.1994.62062067.X |
0.493 |
|
1993 |
Schuldiner S, Liu Y, Edwards RH. Reserpine binding to a vesicular amine transporter expressed in Chinese hamster ovary fibroblasts. The Journal of Biological Chemistry. 268: 29-34. PMID 8416935 |
0.49 |
|
1993 |
Taglicht D, Padan E, Schuldiner S. Proton-sodium stoichiometry of NhaA, an electrogenic antiporter from Escherichia coli. The Journal of Biological Chemistry. 268: 5382-7. PMID 8383669 |
0.324 |
|
1993 |
Gerchman Y, Olami Y, Rimon A, Taglicht D, Schuldiner S, Padan E. Histidine-226 is part of the pH sensor of NhaA, a Na+/H+ antiporter in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 90: 1212-6. PMID 8381959 DOI: 10.1073/Pnas.90.4.1212 |
0.377 |
|
1993 |
Padan E, Schuldiner S. Na+/H+ antiporters, molecular devices that couple the Na+ and H+ circulation in cells. Journal of Bioenergetics and Biomembranes. 25: 647-69. PMID 8144493 DOI: 10.1007/Bf00770252 |
0.377 |
|
1993 |
Ahmed M, Borsch CM, Neyfakh AA, Schuldiner S. Mutants of the Bacillus subtilis multidrug transporter Bmr with altered sensitivity to the antihypertensive alkaloid reserpine. The Journal of Biological Chemistry. 268: 11086-9. PMID 8098708 |
0.424 |
|
1993 |
Pinner E, Kotler Y, Padan E, Schuldiner S. Physiological role of nhaB, a specific Na+/H+ antiporter in Escherichia coli. The Journal of Biological Chemistry. 268: 1729-34. PMID 8093613 |
0.325 |
|
1993 |
Schuldiner S, Steiner-Mordoch S, Yelin R, Wall SC, Rudnick G. Amphetamine derivatives interact with both plasma membrane and secretory vesicle biogenic amine transporters. Molecular Pharmacology. 44: 1227-31. PMID 7903417 |
0.5 |
|
1992 |
Liu Y, Peter D, Roghani A, Schuldiner S, Privé GG, Eisenberg D, Brecha N, Edwards RH. A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter. Cell. 70: 539-51. PMID 1505023 DOI: 10.1016/0092-8674(92)90425-C |
0.521 |
|
1992 |
Suchi R, Stern-Bach Y, Schuldiner S. Modification of arginyl or histidyl groups affects the energy coupling of the amine transporter. Biochemistry. 31: 12500-3. PMID 1463736 DOI: 10.1021/Bi00164A029 |
0.79 |
|
1992 |
Stern-Bach Y, Keen JN, Bejerano M, Steiner-Mordoch S, Wallach M, Findlay JB, Schuldiner S. Homology of a vesicular amine transporter to a gene conferring resistance to 1-methyl-4-phenylpyridinium. Proceedings of the National Academy of Sciences of the United States of America. 89: 9730-3. PMID 1357668 DOI: 10.1073/Pnas.89.20.9730 |
0.767 |
|
1992 |
Pinner E, Padan E, Schuldiner S. Cloning, sequencing, and expression of the nhaB gene, encoding a Na+/H+ antiporter in Escherichia coli. The Journal of Biological Chemistry. 267: 11064-8. PMID 1317851 |
0.35 |
|
1992 |
Pinner E, Carmel O, Bercovier H, Sela S, Padan E, Schuldiner S. Cloning, sequencing and expression of the nhaA and nhaR genes from Salmonella enteritidis. Archives of Microbiology. 157: 323-8. PMID 1317153 DOI: 10.1007/Bf00248676 |
0.349 |
|
1992 |
Rahav-Manor O, Carmel O, Karpel R, Taglicht D, Glaser G, Schuldiner S, Padan E. NhaR, a protein homologous to a family of bacterial regulatory proteins (LysR), regulates nhaA, the sodium proton antiporter gene in Escherichia coli. The Journal of Biological Chemistry. 267: 10433-8. PMID 1316901 |
0.304 |
|
1991 |
Suchi R, Stern-Bach Y, Gabay T, Schuldiner S. Covalent modification of the amine transporter with N,N'-dicyclohexylcarbodiimide. Biochemistry. 30: 6490-4. PMID 2054348 DOI: 10.1021/Bi00240A020 |
0.746 |
|
1990 |
Stern-Bach Y, Greenberg-Ofrath N, Flechner I, Schuldiner S. Identification and purification of a functional amine transporter from bovine chromaffin granules. The Journal of Biological Chemistry. 265: 3961-6. PMID 2303487 |
0.788 |
|
1990 |
Rudnick G, Steiner-Mordoch SS, Fishkes H, Stern-Bach Y, Schuldiner S. Energetics of reserpine binding and occlusion by the chromaffin granule biogenic amine transporter. Biochemistry. 29: 603-8. PMID 2140052 DOI: 10.1021/Bi00455A002 |
0.785 |
|
1989 |
Shirvan MH, Schuldiner S, Rottem S. Role of Na+ cycle in cell volume regulation of Mycoplasma gallisepticum. Journal of Bacteriology. 171: 4410-6. PMID 2753860 DOI: 10.1128/Jb.171.8.4410-4416.1989 |
0.392 |
|
1989 |
Padan E, Maisler N, Taglicht D, Karpel R, Schuldiner S. Deletion of ant in Escherichia coli reveals its function in adaptation to high salinity and an alternative Na+/H+ antiporter system(s). The Journal of Biological Chemistry. 264: 20297-302. PMID 2555351 |
0.331 |
|
1989 |
Rudnick G, Kirk KL, Fishkes H, Schuldiner S. Zwitterionic and anionic forms of a serotonin analog as transport substrates. The Journal of Biological Chemistry. 264: 14865-8. PMID 2549040 |
0.429 |
|
1989 |
Shirvan MH, Schuldiner S, Rottem S. Volume regulation in Mycoplasma gallisepticum: evidence that Na+ is extruded via a primary Na+ pump. Journal of Bacteriology. 171: 4417-24. PMID 2526806 DOI: 10.1128/Jb.171.8.4417-4424.1989 |
0.428 |
|
1987 |
Schuldiner S, Gabizon R, Stern Y, Suchi R. The amine transporter from bovine chromaffin granules: photolabeling and partial purification. Annals of the New York Academy of Sciences. 493: 189-93. PMID 3473960 DOI: 10.1111/J.1749-6632.1987.Tb27200.X |
0.543 |
|
1987 |
Padan E, Schuldiner S. Intracellular pH and membrane potential as regulators in the prokaryotic cell. The Journal of Membrane Biology. 95: 189-98. PMID 3295250 DOI: 10.1007/Bf01869481 |
0.345 |
|
1987 |
Goldberg EB, Arbel T, Chen J, Karpel R, Mackie GA, Schuldiner S, Padan E. Characterization of a Na+/H+ antiporter gene of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 84: 2615-9. PMID 3033655 DOI: 10.1073/Pnas.84.9.2615 |
0.32 |
|
1986 |
Padan E, Schuldiner S. Intracellular pH regulation in bacterial cells. Methods in Enzymology. 125: 337-52. PMID 3713535 DOI: 10.1016/S0076-6879(86)25029-6 |
0.363 |
|
1986 |
Schuldiner S, Agmon V, Brandsma J, Cohen A, Friedman E, Padan E. Induction of SOS functions by alkaline intracellular pH in Escherichia coli. Journal of Bacteriology. 168: 936-9. PMID 3096964 DOI: 10.1128/Jb.168.2.936-939.1986 |
0.342 |
|
1985 |
Gabizon R, Schuldiner S. The amine transporter from bovine chromaffin granules. Partial purification. The Journal of Biological Chemistry. 260: 3001-5. PMID 3972813 |
0.461 |
|
1985 |
Schuldiner S, Gabizon R, Maron R, Suchi R, Stern Y. The amine transporter from bovine chromaffin granules. Annals of the New York Academy of Sciences. 456: 268-76. PMID 2868685 DOI: 10.1111/J.1749-6632.1985.Tb14875.X |
0.532 |
|
1984 |
Zilberstein D, Agmon V, Schuldiner S, Padan E. Escherichia coli intracellular pH, membrane potential, and cell growth. Journal of Bacteriology. 158: 246-52. PMID 6325389 DOI: 10.1128/Jb.158.1.246-252.1984 |
0.351 |
|
1983 |
Maron R, Stern Y, Kanner BI, Schuldiner S. Functional asymmetry of the amine transporter from chromaffin granules. The Journal of Biological Chemistry. 258: 11476-81. PMID 6311813 |
0.398 |
|
1982 |
Gabizon R, Yetinson T, Schuldiner S. Photoinactivation and identification of the biogenic amine transporter in chromaffin granules from bovine adrenal medulla. The Journal of Biological Chemistry. 257: 15145-50. PMID 7174689 |
0.455 |
|
1982 |
Schuldiner S, Rozengurt E. Na+/H+ antiport in Swiss 3T3 cells: mitogenic stimulation leads to cytoplasmic alkalinization. Proceedings of the National Academy of Sciences of the United States of America. 79: 7778-82. PMID 6961450 DOI: 10.1073/Pnas.79.24.7778 |
0.355 |
|
1980 |
Rudnick G, Fishkes H, Nelson PJ, Schuldiner S. Evidence for two distinct serotonin transport systems in platelets. The Journal of Biological Chemistry. 255: 3638-41. PMID 7364762 |
0.413 |
|
1980 |
Kanner BI, Sharon I, Maron R, Schuldiner S. Electrogenic transport of biogenic amines in chromaffin granule membrane vesicles. Febs Letters. 111: 83-6. PMID 7358168 DOI: 10.1016/0014-5793(80)80766-6 |
0.475 |
|
1980 |
Zilberstein D, Padan E, Schuldiner S. A single locus in Escherichia coli governs growth in alkaline pH and on carbon sources whose transport is sodium dependent. Febs Letters. 116: 177-80. PMID 6997070 DOI: 10.1016/0014-5793(80)80637-5 |
0.374 |
|
1980 |
Schuldiner S, Maron R, Kanner BI. Active transport of biogenic amines in chromaffin granule membrane vesicles. Monographs in Neural Sciences. 7: 117-28. PMID 6453280 DOI: 10.1159/000388819 |
0.531 |
|
1980 |
Kanner BI, Sharon I, Maron R, Schuldiner S. Electrogenic transport of biogenic amines in chromaffin granule membrane vesicle (1980) FEBS Letters 111, 83-86 Febs Letters. 115: 325. DOI: 10.1016/0014-5793(80)81199-9 |
0.475 |
|
1979 |
Kanner BI, Fishkes H, Maron R, Sharon I, Schuldiner S. Reserpine as a competitive and reversible inhibitor of the catecholamine transporter of bovine chromaffin granules. Febs Letters. 100: 175-8. PMID 437101 DOI: 10.1016/0014-5793(79)81158-8 |
0.486 |
|
1979 |
Maron R, Fishkes H, Kanner BI, Schuldiner S. Solubilization and reconstitution of the catecholamine transporter from bovine chromaffin granules. Biochemistry. 18: 4781-5. PMID 41569 DOI: 10.1021/Bi00589A003 |
0.529 |
|
1979 |
Ramos S, Schuldiner S, Kaback HR. The use of flow dialysis for determinations of deltapH and active transport. Methods in Enzymology. 55: 680-8. PMID 37407 DOI: 10.1016/0076-6879(79)55076-9 |
0.4 |
|
1979 |
Maron R, Kanner BI, Schuldiner S. The role of a transmembrane pH gradient in 5-hydroxy tryptamine uptake by synaptic vesicles from rat brain. Febs Letters. 98: 237-40. PMID 33834 DOI: 10.1016/0014-5793(79)80190-8 |
0.309 |
|
1979 |
Zilberstein D, Schuldiner S, Padan E. Proton electrochemical gradient in Escherichia coli cells and its relation to active transport of lactose. Biochemistry. 18: 669-73. PMID 33700 DOI: 10.1021/Bi00571A018 |
0.494 |
|
1978 |
Schuldiner S, Fishkes H, Kanner BI. Role of a transmembrane pH gradient in epinephrine transport by chromaffin granule membrane vesicles. Proceedings of the National Academy of Sciences of the United States of America. 75: 3713-6. PMID 29292 DOI: 10.1073/Pnas.75.8.3713 |
0.518 |
|
1978 |
Schuldiner S, Fishkes H. Sodium-proton antiport in isolated membrane vesicles of Escherichia coli. Biochemistry. 17: 706-11. PMID 23828 DOI: 10.1021/Bi00597A023 |
0.362 |
|
1977 |
Schuldiner S, Weil R, Robertson DE, Kaback HR. Microenvironment of the binding site in the lac carrier protein. Proceedings of the National Academy of Sciences of the United States of America. 74: 1851-4. PMID 325557 DOI: 10.1073/Pnas.74.5.1851 |
0.338 |
|
1976 |
Rudnick G, Schuldiner S, Kaback HR. Equilibrium between two forms of the lac carrier protein in energized and nonenergized membrane vesicles from Escherichia coli Biochemistry. 15: 5126-5131. PMID 791364 DOI: 10.1021/bi00668a028 |
0.322 |
|
1976 |
Schuldiner S, Weil R, Kaback HR. Energy-dependent binding of dansylgalactoside to the lac carrier protein: direct binding measurements. Proceedings of the National Academy of Sciences of the United States of America. 73: 109-12. PMID 174094 DOI: 10.1073/Pnas.73.1.109 |
0.415 |
|
1976 |
Ramos S, Schuldiner S, Kaback HR. The electrochemical gradient of protons and its relationship to active transport in Escherichia coli membrane vesicles. Proceedings of the National Academy of Sciences of the United States of America. 73: 1892-6. PMID 6961 DOI: 10.1073/Pnas.73.6.1892 |
0.464 |
|
1976 |
Schuldiner S, Rudnick G, Weil R, Kaback HR. Mechanism of β galactoside transport in Escherichia coli membrane vesicles Trends Biochem.Sci.. 1: 41-45. DOI: 10.1016/S0968-0004(76)80181-8 |
0.436 |
|
1976 |
Schuldiner S, Rudnick G, Weil R, Kaback HR. Mechanism of β-galactoside transport in Escherichia coli membrane vesicles Trends in Biochemical Sciences. 1: 41-45. DOI: 10.1016/S0968-0004(76)80181-8 |
0.332 |
|
1975 |
Kaback HR, Rudnick G, Schuldiner S, Short SA. Active transport in isolated bacterial membrane vesicles: binding of beta-galactosides to the LAC carrier protein. Annals of the New York Academy of Sciences. 264: 350-7. PMID 769642 DOI: 10.1111/j.1749-6632.1975.tb31495.x |
0.376 |
|
1975 |
Schuldiner S, Kaback HR. Membrane potential and active transport in membrane vesicles from Escherichia coli. Biochemistry. 14: 5451-61. PMID 172125 DOI: 10.1021/bi00696a011 |
0.318 |
|
1975 |
Patel L, Schuldiner S, Kaback HR. Reversible effects of chaotropic agents on the proton permeability of Escherichia coli membrane vesicles. Proceedings of the National Academy of Sciences of the United States of America. 72: 3387-91. PMID 171661 DOI: 10.1073/Pnas.72.9.3387 |
0.435 |
|
1974 |
Schuldiner S, Padan E, Rottenberg H, Gromet-Elhanan Z, Avron M. Delta pH and membrane potential in bacterial chromatophores. Febs Letters. 49: 174-7. PMID 4216516 DOI: 10.1016/0014-5793(74)80505-3 |
0.338 |
|
1973 |
Schuldiner S, Rottenberg H, Avron M. Stimulation of ATP synthesis by a membrane potential in chloroplasts. European Journal of Biochemistry / Febs. 39: 455-62. PMID 4129992 DOI: 10.1111/J.1432-1033.1973.Tb03144.X |
0.363 |
|
1971 |
Schuldiner S, Avron M. On the mechanism of the energy-dependent quenching of atebrin fluorescence in isolated chloroplasts. Febs Letters. 14: 233-236. PMID 11945766 DOI: 10.1016/0014-5793(71)80625-7 |
0.33 |
|
1971 |
Schuldiner S, Avron M. Anion permeability of chloroplasts. European Journal of Biochemistry / Febs. 19: 227-31. PMID 5552391 DOI: 10.1111/J.1432-1033.1971.Tb01308.X |
0.332 |
|
1971 |
Walz D, Schuldiner S, Avron M. Photoreactions of chloroplasts in a glycine medium. European Journal of Biochemistry / Febs. 22: 439-44. PMID 5132193 DOI: 10.1111/J.1432-1033.1971.Tb01562.X |
0.334 |
|
1969 |
Schuldiner S, Ohad I. Biogenesis of chloroplast membranes. 3. Light-dependent induction of proton pump activity in whole cells and its correlation to cytochrome f photooxidation during greening of a Chlamydomonas reinhardti mutant (y-I). Biochimica Et Biophysica Acta. 180: 165-77. PMID 5787264 DOI: 10.1016/0005-2728(69)90203-5 |
0.33 |
|
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