☰

Matthew D. Lynes, Ph.D. - Publications

Affiliations: 
2012 Boston University, Boston, MA, United States 
Area:
Biochemistry, Nutrition
Tree Info Grants Similar researchers PubMed Report error

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Townsend KL, Pritchard E, Coburn JM, Kwon YM, Blaszkiewicz M, Lynes MD, Kaplan DL, Tseng YH. Silk Hydrogel-Mediated Delivery of Bone Morphogenetic Protein 7 Directly to Subcutaneous White Adipose Tissue Increases Browning and Energy Expenditure. Frontiers in Bioengineering and Biotechnology. 10: 884601. PMID 35646839 DOI: 10.3389/fbioe.2022.884601  0.695
2022 Lynes MD, Carlone DL, Townsend KL, Breault DT, Tseng YH. Telomerase Reverse Transcriptase Expression Marks a Population of Rare Adipose Tissue Stem Cells. Stem Cells (Dayton, Ohio). 40: 102-111. PMID 35511869 DOI: 10.1093/stmcls/sxab005  0.649
2021 Angueira AR, Sakers AP, Holman CD, Cheng L, Arbocco MN, Shamsi F, Lynes MD, Shrestha R, Okada C, Batmanov K, Susztak K, Tseng YH, Liaw L, Seale P. Defining the lineage of thermogenic perivascular adipose tissue. Nature Metabolism. PMID 33846639 DOI: 10.1038/s42255-021-00380-0  0.418
2021 Shamsi F, Piper M, Ho LL, Huang TL, Gupta A, Streets A, Lynes MD, Tseng YH. Vascular smooth muscle-derived Trpv1 progenitors are a source of cold-induced thermogenic adipocytes. Nature Metabolism. PMID 33846638 DOI: 10.1038/s42255-021-00373-z  0.375
2021 Schlein C, Fischer AW, Sass F, Worthmann A, Tödter K, Jaeckstein MY, Behrens J, Lynes MD, Kiebish MA, Narain NR, Bussberg V, Darkwah A, Jespersen NZ, Nielsen S, Scheele C, et al. Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution. Cell Reports. 34: 108624. PMID 33440156 DOI: 10.1016/j.celrep.2020.108624  0.37
2020 Wang CH, Lundh M, Fu A, Kriszt R, Huang TL, Lynes MD, Leiria LO, Shamsi F, Darcy J, Greenwood BP, Narain NR, Tolstikov V, Smith KL, Emanuelli B, Chang YT, et al. CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice. Science Translational Medicine. 12. PMID 32848096 DOI: 10.1126/Scitranslmed.Aaz8664  0.485
2020 Darcy J, Fang Y, McFadden S, Lynes MD, Leiria LO, Dreyfuss JM, Bussburg V, Tolstikov V, Greenwood B, Narain NR, Kiebish MA, Bartke A, Tseng YH. Integrated metabolomics reveals altered lipid metabolism in adipose tissue in a model of extreme longevity. Geroscience. PMID 32632845 DOI: 10.1007/s11357-020-00221-0  0.393
2020 Lynes MD, Tseng YH. Commentary on: "The Presence of Active Brown Adipose Tissue Determines Cold-Induced Energy Expenditure and Oxylipin Profiles in Humans". The Journal of Clinical Endocrinology and Metabolism. 105. PMID 32559764 DOI: 10.1210/Clinem/Dgaa339  0.457
2020 Shamsi F, Xue R, Huang TL, Lundh M, Liu Y, Leiria LO, Lynes MD, Kempf E, Wang CH, Sugimoto S, Nigro P, Landgraf K, Schulz T, Li Y, Emanuelli B, et al. FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis. Nature Communications. 11: 1421. PMID 32184391 DOI: 10.1038/S41467-020-15055-9  0.402
2020 Sato M, Tsuji T, Yang K, Ren X, Dreyfuss JM, Huang TL, Wang CH, Shamsi F, Leiria LO, Lynes MD, Yau KW, Tseng YH. Cell-autonomous light sensitivity via Opsin3 regulates fuel utilization in brown adipocytes. Plos Biology. 18: e3000630. PMID 32040503 DOI: 10.1371/Journal.Pbio.3000630  0.469
2020 Kodani S, Lynes M, Shamsi F, Wang C, Sugimoto S, Xue R, Huang TL, White AP, Cypess AM, Tseng Y. 1701-P: The Role of UGT1a in Regulating Brown Adipose Tissue and Thermogenic Function Diabetes. 69. DOI: 10.2337/Db20-1701-P  0.473
2019 Lynes MD, Kodani SD, Tseng YH. Lipokines and Thermogenesis. Endocrinology. PMID 31504387 DOI: 10.1210/En.2019-00337  0.432
2019 Leiria LO, Wang CH, Lynes MD, Yang K, Shamsi F, Sato M, Sugimoto S, Chen EY, Bussberg V, Narain NR, Sansbury BE, Darcy J, Huang TL, Kodani SD, Sakaguchi M, et al. 12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat. Cell Metabolism. PMID 31353262 DOI: 10.1016/J.Cmet.2019.07.001  0.429
2019 Darcy J, Wang C, Lundh M, Shamsi F, Lynes M, D'aprigny T, Emanuelli B, Tseng Y. 1999-P: Cysteine-Rich Protein 2 (CRIP2) Is a Novel Transcriptional Regulator of Uncoupling Protein 1 Diabetes. 68. DOI: 10.2337/Db19-1999-P  0.397
2018 Lynes MD, Shamsi F, Sustarsic EG, Leiria LO, Wang CH, Su SC, Huang TL, Gao F, Narain NR, Chen EY, Cypess AM, Schulz TJ, Gerhart-Hines Z, Kiebish MA, Tseng YH. Cold-Activated Lipid Dynamics in Adipose Tissue Highlights a Role for Cardiolipin in Thermogenic Metabolism. Cell Reports. 24: 781-790. PMID 30021173 DOI: 10.1016/J.Celrep.2018.06.073  0.488
2018 Sustarsic EG, Ma T, Lynes MD, Larsen M, Karavaeva I, Havelund JF, Nielsen CH, Jedrychowski MP, Moreno-Torres M, Lundh M, Plucinska K, Jespersen NZ, Grevengoed TJ, Kramar B, Peics J, et al. Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis. Cell Metabolism. PMID 29861389 DOI: 10.1016/J.Cmet.2018.05.003  0.475
2018 Stanford KI, Lynes MD, Takahashi H, Baer LA, Arts PJ, May FJ, Lehnig AC, Middelbeek RJW, Richard JJ, So K, Chen EY, Gao F, Narain NR, Distefano G, Shettigar VK, et al. 12,13-diHOME: An Exercise-Induced Lipokine that Increases Skeletal Muscle Fatty Acid Uptake. Cell Metabolism. 27: 1111-1120.e3. PMID 29719226 DOI: 10.1016/J.Cmet.2018.03.020  0.334
2018 Bartelt A, Widenmaier SB, Schlein C, Johann K, Goncalves RLS, Eguchi K, Fischer AW, Parlakgül G, Snyder NA, Nguyen TB, Bruns OT, Franke D, Bawendi MG, Lynes MD, Leiria LO, et al. Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity. Nature Medicine. PMID 29400713 DOI: 10.1038/Nm.4481  0.479
2017 Ramirez AK, Lynes MD, Shamsi F, Xue R, Tseng YH, Kahn CR, Kasif S, Dreyfuss JM. Integrating Extracellular Flux Measurements and Genome-Scale Modeling Reveals Differences between Brown and White Adipocytes. Cell Reports. 21: 3040-3048. PMID 29241534 DOI: 10.1016/J.Celrep.2017.11.065  0.389
2017 Lynes MD, Leiria LO, Lundh M, Bartelt A, Shamsi F, Huang TL, Takahashi H, Hirshman MF, Schlein C, Lee A, Baer LA, May FJ, Gao F, Narain NR, Chen EY, et al. Corrigendum: The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue. Nature Medicine. 23: 1384. PMID 29117173 DOI: 10.1038/Nm1117-1384B  0.401
2017 Townsend KL, Madden C, Blaszkiewicz M, McDougall L, Tupone D, Lynes MD, Mishina Y, Yu P, Morrison S, Tseng YH. Re-Establishment of Energy Balance in a Male Mouse Model with POMC Neuron Deletion of BMPR1A. Endocrinology. PMID 29040444 DOI: 10.1210/En.2017-00212  0.666
2017 Lynes MD, Tseng YH. Deciphering adipose tissue heterogeneity. Annals of the New York Academy of Sciences. PMID 28763833 DOI: 10.1111/Nyas.13398  0.477
2017 Lynes MD, Leiria LO, Lundh M, Bartelt A, Shamsi F, Huang TL, Takahashi H, Hirshman MF, Schlein C, Lee A, Baer LA, May FJ, Gao F, Narain NR, Chen EY, et al. The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue. Nature Medicine. PMID 28346411 DOI: 10.1038/Nm.4297  0.508
2016 Zhu Y, Gao Y, Tao C, Shao M, Zhao S, Huang W, Yao T, Johnson JA, Liu T, Cypess AM, Gupta O, Holland WL, Gupta RK, Spray DC, Tanowitz HB, ... ... Lynes MD, et al. Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals. Cell Metabolism. 24: 420-433. PMID 27626200 DOI: 10.1016/J.Cmet.2016.08.005  0.447
2016 Schulz TJ, Graja A, Huang TL, Xue R, An D, Poehle-Kronawitter S, Lynes MD, Tolkachov A, O'Sullivan LE, Hirshman MF, Schupp M, Goodyear LJ, Mishina Y, Tseng YH. Loss of BMP receptor type 1A in murine adipose tissue attenuates age-related onset of insulin resistance. Diabetologia. PMID 27209464 DOI: 10.1007/S00125-016-3990-8  0.426
2015 Lynes MD, Tseng YH. The Thermogenic Circuit: Regulators of Thermogenic Competency and Differentiation. Genes & Diseases. 2: 164-172. PMID 26491708 DOI: 10.1016/J.Gendis.2015.03.001  0.423
2015 Zhang X, Tian Y, Zhang H, Kavishwar A, Lynes M, Brownell AL, Sun H, Tseng YH, Moore A, Ran C. Curcumin analogues as selective fluorescence imaging probes for brown adipose tissue and monitoring browning. Scientific Reports. 5: 13116. PMID 26269357 DOI: 10.1038/Srep13116  0.413
2015 Xue R, Lynes MD, Dreyfuss JM, Shamsi F, Schulz TJ, Zhang H, Huang TL, Townsend KL, Li Y, Takahashi H, Weiner LS, White AP, Lynes MS, Rubin LL, Goodyear LJ, et al. Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes. Nature Medicine. 21: 760-8. PMID 26076036 DOI: 10.1038/Nm.3881  0.687
2015 Lynes MD, Schulz TJ, Pan AJ, Tseng YH. Disruption of insulin signaling in Myf5-expressing progenitors leads to marked paucity of brown fat but normal muscle development. Endocrinology. 156: 1637-47. PMID 25625589 DOI: 10.1210/En.2014-1773  0.431
2014 Lynes MD, Tseng YH. Unwiring the transcriptional heat circuit. Proceedings of the National Academy of Sciences of the United States of America. 111: 14318-9. PMID 25261553 DOI: 10.1073/Pnas.1416145111  0.486
2014 Castiglioni A, Hettmer S, Lynes MD, Rao TN, Tchessalova D, Sinha I, Lee BT, Tseng YH, Wagers AJ. Isolation of progenitors that exhibit myogenic/osteogenic bipotency in vitro by fluorescence-activated cell sorting from human fetal muscle. Stem Cell Reports. 2: 92-106. PMID 24678452 DOI: 10.1016/J.Stemcr.2013.12.006  0.32
2013 Townsend KL, An D, Lynes MD, Huang TL, Zhang H, Goodyear LJ, Tseng YH. Increased mitochondrial activity in BMP7-treated brown adipocytes, due to increased CPT1- and CD36-mediated fatty acid uptake. Antioxidants & Redox Signaling. 19: 243-57. PMID 22938691 DOI: 10.1089/Ars.2012.4536  0.695
2011 Lynes M, Narisawa S, Millán JL, Widmaier EP. Interactions between CD36 and global intestinal alkaline phosphatase in mouse small intestine and effects of high-fat diet. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 301: R1738-47. PMID 21900644 DOI: 10.1152/Ajpregu.00235.2011  0.645
2011 Lynes MD, Widmaier EP. Involvement of CD36 and intestinal alkaline phosphatases in fatty acid transport in enterocytes, and the response to a high-fat diet. Life Sciences. 88: 384-91. PMID 21172358 DOI: 10.1016/J.Lfs.2010.12.015  0.637
Show low-probability matches.