Year |
Citation |
Score |
2020 |
Jiang X, Yuan Y, Huang J, Zhang S, Luo S, Wang N, Pu D, Zhao N, Tang Q, Hirata K, Yang X, Jiao Y, Sakata-Kato T, Wu JW, Yan C, ... ... Yin H, et al. Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum. Cell. PMID 32860739 DOI: 10.1016/J.Cell.2020.08.015 |
0.491 |
|
2020 |
Wang Y, Zhang S, Li H, Wang H, Zhang T, Hutchinson MR, Yin H, Wang X. Small-Molecule Modulators of Toll-like Receptors. Accounts of Chemical Research. PMID 32233400 DOI: 10.1021/Acs.Accounts.9B00631 |
0.615 |
|
2020 |
Jiang S, Tanji H, Yin K, Zhang S, Sakaniwa K, Huang J, Yang Y, Li J, Ohto U, Shimizu T, Yin HH. Rationally designed small-molecule inhibitors targeting an unconventional pocket on the TLR8 protein-protein interface. Journal of Medicinal Chemistry. PMID 32233366 DOI: 10.1021/Acs.Jmedchem.9B02128 |
0.687 |
|
2019 |
Russell AE, Sneider A, Witwer KW, Bergese P, Bhattacharyya SN, Cocks A, Cocucci E, Erdbrügger U, Falcon-Perez JM, Freeman DW, Gallagher TM, Hu S, Huang Y, Jay SM, Kano SI, ... ... Yin H, et al. Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop. Journal of Extracellular Vesicles. 8: 1684862. PMID 31762963 DOI: 10.1080/20013078.2019.1684862 |
0.331 |
|
2019 |
Padilla-Salinas R, Anderson R, Sakaniwa K, Zhang S, Nordeen P, Lu C, Shimizu T, Yin HH. Discovery of Novel Small Molecule Dual Inhibitors Targeting Toll-like Receptor 7 and 8. Journal of Medicinal Chemistry. PMID 31687820 DOI: 10.1021/Acs.Jmedchem.9B01201 |
0.666 |
|
2019 |
Peng Y, Zhang X, Zhang T, Grace PM, Li H, Wang Y, Li H, Chen H, Watkins LR, Hutchinson MR, Yin H, Wang X. Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain. Brain, Behavior, and Immunity. PMID 31542403 DOI: 10.1016/J.Bbi.2019.09.013 |
0.575 |
|
2019 |
Zhang Y, Jin X, Liang J, Guo Y, Sun G, Zeng X, Yin H. Extracellular vesicles derived from ODN-stimulated macrophages transfer and activate Cdc42 in recipient cells and thereby increase cellular permissiveness to EV uptake. Science Advances. 5: eaav1564. PMID 31355328 DOI: 10.1126/Sciadv.Aav1564 |
0.322 |
|
2019 |
Tamura R, Balabanova A, Frakes SA, Bargmann A, Grimm J, Koch TH, Yin HH. Photoactivatable Prodrug of Doxazolidine Targeting Exosomes. Journal of Medicinal Chemistry. PMID 30703330 DOI: 10.1021/Acs.Jmedchem.8B01508 |
0.325 |
|
2018 |
Hu Z, Tanji H, Jiang S, Zhang S, Koo K, Chan J, Sakaniwa K, Ohto U, Candia A, Shimizu T, Yin H. Small-Molecule TLR8 Antagonists via Structure-Based Rational Design. Cell Chemical Biology. PMID 30100350 DOI: 10.1016/J.Chembiol.2018.07.004 |
0.685 |
|
2018 |
Sammond DW, Kastelowitz N, Donohoe BS, Alahuhta M, Lunin VV, Chung D, Sarai NS, Yin H, Mittal A, Himmel ME, Guss AM, Bomble YJ. An iterative computational design approach to increase the thermal endurance of a mesophilic enzyme. Biotechnology For Biofuels. 11: 189. PMID 30002729 DOI: 10.1186/S13068-018-1178-9 |
0.695 |
|
2018 |
Bhattacharyya S, Wang W, Qin W, Cheng K, Coulup S, Chavez S, Jiang S, Raparia K, De Almeida LMV, Stehlik C, Tamaki Z, Yin H, Varga J. TLR4-dependent fibroblast activation drives persistent organ fibrosis in skin and lung. Jci Insight. 3. PMID 29997297 DOI: 10.1172/Jci.Insight.98850 |
0.514 |
|
2018 |
Zhang L, Shi L, Soars S, Kamps J, Yin HH. Discovery of Novel Small-molecule Inhibitors of Nuclear Factor-κB Signaling with Anti-inflammatory and Anti-cancer Properties. Journal of Medicinal Chemistry. PMID 29870245 DOI: 10.1021/Acs.Jmedchem.7B01557 |
0.338 |
|
2018 |
Grace PM, Wang X, Strand KA, Baratta MV, Zhang Y, Galer EL, Yin H, Maier SF, Watkins LR. DREADDed microglia in pain: Implications for spinal inflammatory signaling in male rats. Experimental Neurology. PMID 29530713 DOI: 10.1016/J.Expneurol.2018.03.005 |
0.539 |
|
2017 |
Zhang S, Hu Z, Tanji H, Jiang S, Das N, Li J, Sakaniwa K, Jin J, Bian Y, Ohto U, Shimizu T, Yin H. Small-molecule inhibition of TLR8 through stabilization of its resting state. Nature Chemical Biology. PMID 29155428 DOI: 10.1038/Nchembio.2518 |
0.749 |
|
2017 |
Bhattacharyya S, Midwood KS, Yin H, Varga J. Toll-Like Receptor-4 Signaling Drives Persistent Fibroblast Activation and Prevents Fibrosis Resolution in Scleroderma. Advances in Wound Care. 6: 356-369. PMID 29062592 DOI: 10.1089/Wound.2017.0732 |
0.322 |
|
2017 |
Kargas V, Marzinek JK, Holdbrook DA, Yin H, Ford RC, Bond PJ. A Polar SxxS Motif Drives Assembly of the Transmembrane Domains of Toll-Like Receptor 4. Biochimica Et Biophysica Acta. PMID 28739292 DOI: 10.1016/J.Bbamem.2017.07.010 |
0.403 |
|
2017 |
Kastelowitz N, Tamura R, Onasoga A, Stalker TJ, White OR, Brown PN, Brodsky GL, Brass LF, Branchford BR, Di Paola J, Yin H. Peptides derived from MARCKS block coagulation complex assembly on phosphatidylserine. Scientific Reports. 7: 4275. PMID 28655899 DOI: 10.1038/S41598-017-04494-Y |
0.387 |
|
2017 |
Zhang L, Dewan V, Yin HH. Discovery of Small Molecules as Multi-Toll-like Receptor Agonists with Proinflammatory and Anticancer Activities. Journal of Medicinal Chemistry. PMID 28537730 DOI: 10.1021/Acs.Jmedchem.7B00419 |
0.665 |
|
2017 |
Zeng X, Wu P, Yao C, Liang J, Zhang ST, Yin HH. Small molecule and peptide recognition of protein transmembrane domains. Biochemistry. PMID 28353343 DOI: 10.1021/Acs.Biochem.6B00909 |
0.612 |
|
2017 |
Tamura R, Yin H. Rationally Designed Peptide Probes for Extracellular Vesicles. Advances in Clinical Chemistry. 79: 25-41. PMID 28212713 DOI: 10.1016/Bs.Acc.2016.09.001 |
0.408 |
|
2017 |
de Jesus AJ, Yin H. Computational Design of Membrane Curvature-Sensing Peptides. Methods in Molecular Biology (Clifton, N.J.). 1529: 417-437. PMID 27914065 DOI: 10.1007/978-1-4939-6637-0_22 |
0.8 |
|
2016 |
Das N, Dewan V, Grace PM, Gunn RJ, Tamura R, Tzarum N, Watkins LR, Wilson IA, Yin H. HMGB1 Activates Proinflammatory Signaling via TLR5 Leading to Allodynia. Cell Reports. 17: 1128-1140. PMID 27760316 DOI: 10.1016/J.Celrep.2016.09.076 |
0.776 |
|
2016 |
de Jesus AJ, White OR, Flynn AD, Yin H. Determinants of Curvature-Sensing Behavior for MARCKS-Fragment Peptides. Biophysical Journal. 110: 1980-92. PMID 27166806 DOI: 10.1016/J.Bpj.2016.04.007 |
0.805 |
|
2016 |
Flynn AD, Yin H. Lipid-Targeting Peptide Probes for Extracellular Vesicles. Journal of Cellular Physiology. PMID 26909741 DOI: 10.1002/Jcp.25354 |
0.394 |
|
2016 |
Yin H, Flynn AD. Drugging Membrane Protein Interactions. Annual Review of Biomedical Engineering. PMID 26863923 DOI: 10.1146/Annurev-Bioeng-092115-025322 |
0.38 |
|
2016 |
Sammond DW, Kastelowitz N, Himmel ME, Yin H, Crowley MF, Bomble YJ. Comparing Residue Clusters from Thermophilic and Mesophilic Enzymes Reveals Adaptive Mechanisms. Plos One. 11: e0145848. PMID 26741367 DOI: 10.1371/Journal.Pone.0145848 |
0.709 |
|
2016 |
Yan L, Liang J, Yao C, Wu P, Zeng X, Cheng K, Yin H. Cover Picture: Pyrimidine Triazole Thioether Derivatives as Toll-Like Receptor 5 (TLR5)/Flagellin Complex Inhibitors (ChemMedChem 8/2016) Chemmedchem. 11: 730-730. DOI: 10.1002/Cmdc.201600184 |
0.513 |
|
2015 |
Wang T, de Jesus AJ, Shi Y, Yin H. Pyridoxamine is a substrate of the energy-coupling factor transporter HmpT. Cell Discovery. 1: 15014. PMID 27462413 DOI: 10.1038/Celldisc.2015.14 |
0.76 |
|
2015 |
Yan L, Liang J, Yao C, Wu P, Zeng X, Cheng K, Yin H. Pyrimidine Triazole Thioether Derivatives as Toll-Like Receptor 5 (TLR5)/Flagellin Complex Inhibitors. Chemmedchem. PMID 26634412 DOI: 10.1002/Cmdc.201500471 |
0.572 |
|
2015 |
Wang X, Zhang Y, Peng Y, Hutchinson MR, Rice KC, Yin H, Watkins LR. Pharmacological characterization of the opioid inactive isomers (+)-naltrexone and (+)-naloxone as Toll-like receptor 4 antagonists. British Journal of Pharmacology. PMID 26603732 DOI: 10.1111/Bph.13394 |
0.533 |
|
2015 |
Yu S, Wang S, Yu H, Feng Y, Zhang S, Zhu M, Yin H, Meng X. A ratiometric two-photon fluorescent probe for hydrazine and its applications. Sensors and Actuators. B, Chemical. 220: 1338-1345. PMID 26500394 DOI: 10.1016/J.Snb.2015.07.051 |
0.485 |
|
2015 |
Li J, Csakai A, Jin J, Zhang F, Yin H. Therapeutic Developments Targeting Toll-like Receptor-4-Mediated Neuroinflammation. Chemmedchem. PMID 26136385 DOI: 10.1002/Cmdc.201500188 |
0.391 |
|
2015 |
Cheng K, Gao M, Godfroy JI, Brown PN, Kastelowitz N, Yin H. Specific activation of the TLR1-TLR2 heterodimer by small-molecule agonists. Science Advances. 1. PMID 26101787 DOI: 10.1126/Sciadv.1400139 |
0.521 |
|
2015 |
Selfridge BR, Wang X, Zhang Y, Yin H, Grace PM, Watkins LR, Jacobson AE, Rice KC. Structure-Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists. Journal of Medicinal Chemistry. 58: 5038-52. PMID 26010811 DOI: 10.1021/Acs.Jmedchem.5B00426 |
0.554 |
|
2015 |
Daniele SG, Béraud D, Davenport C, Cheng K, Yin H, Maguire-Zeiss KA. Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders. Science Signaling. 8: ra45. PMID 25969543 DOI: 10.1126/Scisignal.2005965 |
0.505 |
|
2015 |
Yan L, de Jesus AJ, Tamura R, Li V, Cheng K, Yin H. Curvature sensing MARCKS-ED peptides bind to membranes in a stereo-independent manner. Journal of Peptide Science : An Official Publication of the European Peptide Society. 21: 577-85. PMID 25851418 DOI: 10.1002/Psc.2772 |
0.81 |
|
2015 |
Wang X, Wang X, Feng Y, Zhu M, Yin H, Guo Q, Meng X. A two-photon fluorescent probe for detecting endogenous hypochlorite in living cells. Dalton Transactions (Cambridge, England : 2003). 44: 6613-9. PMID 25757874 DOI: 10.1039/C5Dt00012B |
0.378 |
|
2015 |
Gao M, Cheng K, Yin H. Targeting protein-protein interfaces using macrocyclic peptides. Biopolymers. PMID 25664609 DOI: 10.1002/Bip.22625 |
0.577 |
|
2015 |
Northcutt AL, Hutchinson MR, Wang X, Baratta MV, Hiranita T, Cochran TA, Pomrenze MB, Galer EL, Kopajtic TA, Li CM, Amat J, Larson G, Cooper DC, Huang Y, O'Neill CE, ... Yin H, et al. DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling. Molecular Psychiatry. PMID 25644383 DOI: 10.1038/Mp.2014.177 |
0.491 |
|
2015 |
D'Atri LP, Etulain J, Rivadeneyra L, Lapponi MJ, Centurion M, Cheng K, Yin H, Schattner M. Expression and functionality of Toll-like receptor 3 in the megakaryocytic lineage. Journal of Thrombosis and Haemostasis : Jth. 13: 839-50. PMID 25594115 DOI: 10.1111/Jth.12842 |
0.527 |
|
2015 |
Smith C, Wang X, Yin H. Caspases come together over LPS. Trends in Immunology. 36: 59-61. PMID 25573609 DOI: 10.1016/J.It.2014.12.007 |
0.393 |
|
2015 |
Yang H, Chen YZ, Zhang Y, Wang X, Zhao X, Godfroy JI, Liang Q, Zhang M, Zhang T, Yuan Q, Ann Royal M, Driscoll M, Xia NS, Yin H, Xue D. A lysine-rich motif in the phosphatidylserine receptor PSR-1 mediates recognition and removal of apoptotic cells. Nature Communications. 6: 5717. PMID 25564762 DOI: 10.1038/Ncomms6717 |
0.446 |
|
2015 |
Kastelowitz N, Jarvis A, White OR, Brown PN, Brodsky G, Tamura R, Paola JAD, Yin H. MARCKS ED Inhibits Fibrin Formation By Blocking Coagulation Protein Complex Assembly on Phosphatidylserine Blood. 126: 2272-2272. DOI: 10.1182/Blood.V126.23.2272.2272 |
0.399 |
|
2015 |
Grace P, Wang X, Urban D, Baratta M, Galer E, Strand K, Zhang Y, Yin H, Roth B, Maier S, Watkins L. (250) Selective manipulation of spinal microglia by chemogenetics: implications for allodynia and inflammatory signaling The Journal of Pain. 16: S38. DOI: 10.1016/J.Jpain.2015.01.167 |
0.433 |
|
2015 |
Kargas VE, Holdbrook DA, Godfroy JI, Yin H, Ford RC, Bond PJ. Sending Innate Immune Signals Across the Membrane: A Multiscale Simulation Approach to Toll-Like Receptor Assembly Biophysical Journal. 108: 99. DOI: 10.1016/J.Bpj.2014.11.567 |
0.394 |
|
2015 |
Berglund NA, Febbraio MA, Ford RC, Godfroy JI, Holdbrook DA, Kargas VE, Khalid S, Lancaster GI, Yin H, Bond PJ. Establishing the Structural Rules for Ligand Recognition, Signaling and Assembly in Innate Immune Receptors Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.562 |
0.382 |
|
2015 |
Grace P, Wang X, Urban D, Baratta M, Galer E, Strand K, Zhang Y, Yin H, Roth B, Maier S, Watkins L. Selective manipulation of spinal microglia by chemogenetics: Implications for allodynia and inflammatory signaling Brain, Behavior, and Immunity. 49: e7. DOI: 10.1016/J.Bbi.2015.06.045 |
0.544 |
|
2014 |
Gao M, London N, Cheng K, Tamura R, Jin J, Schueler-Furman O, Yin H. Rationally Designed Macrocyclic Peptides as Synergistic Agonists of LPS-Induced Inflammatory Response. Tetrahedron. 70: 7664-7668. PMID 25400297 DOI: 10.1016/J.Tet.2014.07.026 |
0.579 |
|
2014 |
Beninson LA, Brown PN, Loughridge AB, Saludes JP, Maslanik T, Hills AK, Woodworth T, Craig W, Yin H, Fleshner M. Acute stressor exposure modifies plasma exosome-associated heat shock protein 72 (Hsp72) and microRNA (miR-142-5p and miR-203). Plos One. 9: e108748. PMID 25259839 DOI: 10.1371/Journal.Pone.0108748 |
0.677 |
|
2014 |
Grace PM, Ramos KM, Rodgers KM, Wang X, Hutchinson MR, Lewis MT, Morgan KN, Kroll JL, Taylor FR, Strand KA, Zhang Y, Berkelhammer D, Huey MG, Greene LI, Cochran TA, ... Yin H, et al. Activation of adult rat CNS endothelial cells by opioid-induced toll-like receptor 4 (TLR4) signaling induces proinflammatory, biochemical, morphological, and behavioral sequelae. Neuroscience. 280: 299-317. PMID 25241065 DOI: 10.1016/J.Neuroscience.2014.09.020 |
0.553 |
|
2014 |
Morton LA, Tamura R, de Jesus AJ, Espinoza A, Yin H. Biophysical investigations with MARCKS-ED: dissecting the molecular mechanism of its curvature sensing behaviors. Biochimica Et Biophysica Acta. 1838: 3137-44. PMID 25195712 DOI: 10.1016/J.Bbamem.2014.08.027 |
0.798 |
|
2014 |
Li Y, Smith C, Wu H, Teng P, Shi Y, Padhee S, Jones T, Nguyen AM, Cao C, Yin H, Cai J. Short antimicrobial lipo-α/γ-AA hybrid peptides. Chembiochem : a European Journal of Chemical Biology. 15: 2275-80. PMID 25169879 DOI: 10.1002/Cbic.201402264 |
0.497 |
|
2014 |
Kastelowitz N, Yin H. Exosomes and microvesicles: identification and targeting by particle size and lipid chemical probes. Chembiochem : a European Journal of Chemical Biology. 15: 923-8. PMID 24740901 DOI: 10.1002/Cbic.201400043 |
0.368 |
|
2014 |
Padhee S, Smith C, Wu H, Li Y, Manoj N, Qiao Q, Khan Z, Cao C, Yin H, Cai J. The development of antimicrobial a-AApeptides that suppress proinflammatory immune responses. Chembiochem : a European Journal of Chemical Biology. 15: 688-94. PMID 24677440 DOI: 10.1002/Cbic.201300709 |
0.478 |
|
2014 |
Li Y, Smith C, Wu H, Padhee S, Manoj N, Cardiello J, Qiao Q, Cao C, Yin H, Cai J. Lipidated cyclic γ-AApeptides display both antimicrobial and anti-inflammatory activity. Acs Chemical Biology. 9: 211-7. PMID 24144063 DOI: 10.1021/Cb4006613 |
0.519 |
|
2014 |
Beninson L, Campisi J, Brown P, Loughridge A, Saludes J, Hills A, Woodworth T, Craig W, Yin H, Fleshner M. 12. Exposure to acute stress modifies plasma exosomes capable of improving host defense to bacterial challenge Brain, Behavior, and Immunity. 40: e4. DOI: 10.1016/J.Bbi.2014.06.032 |
0.682 |
|
2013 |
Lluis MW, Yin H. Engineering and utilization of reporter cell lines for cell-based assays of transmembrane receptors. Methods in Molecular Biology (Clifton, N.J.). 1063: 211-25. PMID 23975780 DOI: 10.1007/978-1-62703-583-5_12 |
0.354 |
|
2013 |
de Jesus AJ, Kastelowitz N, Yin H. Changes in lipid density induce membrane curvature. Rsc Advances. 3: 13622-13625. PMID 23930220 DOI: 10.1039/C3Ra42332H |
0.785 |
|
2013 |
Saludes JP, Morton LA, Coulup SK, Fiorini Z, Cook BM, Beninson L, Chapman ER, Fleshner M, Yin H. Multivalency amplifies the selection and affinity of bradykinin-derived peptides for lipid nanovesicles. Molecular Biosystems. 9: 2005-9. PMID 23715428 DOI: 10.1039/C3Mb70109C |
0.802 |
|
2013 |
Wang X, Grace PM, Pham MN, Cheng K, Strand KA, Smith C, Li J, Watkins LR, Yin H. Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 2713-22. PMID 23568774 DOI: 10.1096/Fj.12-222992 |
0.66 |
|
2013 |
Li J, Wang X, Zhang F, Yin H. Toll-like receptors as therapeutic targets for autoimmune connective tissue diseases. Pharmacology & Therapeutics. 138: 441-51. PMID 23531543 DOI: 10.1016/J.Pharmthera.2013.03.003 |
0.446 |
|
2013 |
Wang X, Smith C, Yin H. Targeting Toll-like receptors with small molecule agents. Chemical Society Reviews. 42: 4859-66. PMID 23503527 DOI: 10.1039/C3Cs60039D |
0.448 |
|
2013 |
Lee J, Sammond DW, Fiorini Z, Saludes JP, Resch MG, Hao B, Wang W, Yin H, Liu X. Computationally designed peptide inhibitors of the ubiquitin E3 ligase SCF(Fbx4). Chembiochem : a European Journal of Chemical Biology. 14: 445-51. PMID 23401343 DOI: 10.1002/Cbic.201200777 |
0.793 |
|
2013 |
Lluis MW, Godfroy JI, Yin H. Protein engineering methods applied to membrane protein targets. Protein Engineering, Design & Selection : Peds. 26: 91-100. PMID 23118339 DOI: 10.1093/Protein/Gzs079 |
0.365 |
|
2013 |
Morton LA, Yang H, Saludes JP, Fiorini Z, Beninson L, Chapman ER, Fleshner M, Xue D, Yin H. MARCKS-ED peptide as a curvature and lipid sensor. Acs Chemical Biology. 8: 218-25. PMID 23075500 DOI: 10.1021/Cb300429E |
0.805 |
|
2013 |
Coulup SK, Morton LA, Yin H. Abstract 2233: MARCKS-ED peptide targets highly curved vesicles: Potential probe for exosome detection. Cancer Research. 73: 2233-2233. DOI: 10.1158/1538-7445.Am2013-2233 |
0.812 |
|
2012 |
Yin H. Constrained Peptides as Miniature Protein Structures International Scholarly Research Notices. 2012: 692190-692190. PMID 25969758 DOI: 10.5402/2012/692190 |
0.368 |
|
2012 |
Godfroy JI, Roostan M, Moroz YS, Korendovych IV, Yin H. Isolated Toll-like receptor transmembrane domains are capable of oligomerization. Plos One. 7: e48875. PMID 23155421 DOI: 10.1371/Journal.Pone.0048875 |
0.664 |
|
2012 |
Wang X, Fiorini Z, Smith C, Zhang Y, Li J, Watkins LR, Yin H. Repositioning antimicrobial agent pentamidine as a disruptor of the lateral interactions of transmembrane domain 5 of EBV latent membrane protein 1. Plos One. 7: e47703. PMID 23094078 DOI: 10.1371/Journal.Pone.0047703 |
0.598 |
|
2012 |
Zhang S, Cheng K, Wang X, Yin H. Selection, synthesis, and anti-inflammatory evaluation of the arylidene malonate derivatives as TLR4 signaling inhibitors. Bioorganic & Medicinal Chemistry. 20: 6073-9. PMID 22985959 DOI: 10.1016/J.Bmc.2012.08.022 |
0.675 |
|
2012 |
Cheng K, Wang X, Zhang S, Yin H. Discovery of small-molecule inhibitors of the TLR1/TLR2 complex. Angewandte Chemie (International Ed. in English). 51: 12246-9. PMID 22969053 DOI: 10.1002/Anie.201204910 |
0.685 |
|
2012 |
Due MR, Piekarz AD, Wilson N, Feldman P, Ripsch MS, Chavez S, Yin H, Khanna R, White FA. Neuroexcitatory effects of morphine-3-glucuronide are dependent on Toll-like receptor 4 signaling. Journal of Neuroinflammation. 9: 200. PMID 22898544 DOI: 10.1186/1742-2094-9-200 |
0.301 |
|
2012 |
Hutchinson MR, Northcutt AL, Hiranita T, Wang X, Lewis SS, Thomas J, van Steeg K, Kopajtic TA, Loram LC, Sfregola C, Galer E, Miles NE, Bland ST, Amat J, Rozeske RR, ... ... Yin H, et al. Opioid activation of toll-like receptor 4 contributes to drug reinforcement. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11187-200. PMID 22895704 DOI: 10.1523/Jneurosci.0684-12.2012 |
0.535 |
|
2012 |
Miyauchi K, Urano E, Takeda S, Murakami T, Okada Y, Cheng K, Yin H, Kubo M, Komano J. Toll-like receptor (TLR) 3 as a surrogate sensor of retroviral infection in human cells. Biochemical and Biophysical Research Communications. 424: 519-23. PMID 22771581 DOI: 10.1016/J.Bbrc.2012.06.148 |
0.52 |
|
2012 |
Saludes JP, Morton LA, Ghosh N, Beninson LA, Chapman ER, Fleshner M, Yin H. Detection of highly curved membrane surfaces using a cyclic peptide derived from synaptotagmin-I. Acs Chemical Biology. 7: 1629-35. PMID 22769435 DOI: 10.1021/Cb3002705 |
0.802 |
|
2012 |
Morton LA, Saludes JP, Yin H. Constant pressure-controlled extrusion method for the preparation of Nano-sized lipid vesicles. Journal of Visualized Experiments : Jove. PMID 22760481 DOI: 10.3791/4151 |
0.78 |
|
2012 |
Wang X, Saludes JP, Zhao TX, Csakai A, Fiorini Z, Chavez SA, Li J, Lee GI, Varga K, Yin H. Targeting the lateral interactions of transmembrane domain 5 of Epstein-Barr virus latent membrane protein 1. Biochimica Et Biophysica Acta. 1818: 2282-9. PMID 22609737 DOI: 10.1016/J.Bbamem.2012.05.013 |
0.74 |
|
2012 |
Wang X, Loram LC, Ramos K, de Jesus AJ, Thomas J, Cheng K, Reddy A, Somogyi AA, Hutchinson MR, Watkins LR, Yin H. Morphine activates neuroinflammation in a manner parallel to endotoxin. Proceedings of the National Academy of Sciences of the United States of America. 109: 6325-30. PMID 22474354 DOI: 10.1073/Pnas.1200130109 |
0.77 |
|
2012 |
Lee G, Sammond DW, Joce C, Takeshita R, McQuate SE, Ghosh N, Martin JM, Wang X, Zhao TX, Saludes JP, Csakai A, Fiorini Z, Chavez SA, Li J, Varga K, ... Yin H, et al. Investigation of homo-oligomeric interface and binding hotspot of Latent membrane protein-1 (LMP-1) of Epstein-Barr virus (EBV) Rapid Communication in Photoscience. 1: 58-58. DOI: 10.5857/Rcp.2012.1.2.058 |
0.779 |
|
2012 |
Coulup SK, Saludes JP, Yin H. Abstract 4745: Multivalent dendrimeric peptides as new biomarker probes for the detection of cancer metastasis Cancer Research. 72: 4745-4745. DOI: 10.1158/1538-7445.Am2012-4745 |
0.733 |
|
2012 |
Saludes J, Morton L, Ghosh N, Beninson L, Chapman E, Fleshner M, Yin H. Abstract 4743: Exosomes in motion: Visualizing cancer metastasis via the Synaptotagmin C2B domain Cancer Research. 72: 4743-4743. DOI: 10.1158/1538-7445.Am2012-4743 |
0.789 |
|
2012 |
Cheng K, Wang X, Zhang S, Yin H. Inside Back Cover: Discovery of Small‐Molecule Inhibitors of the TLR1/TLR2 Complex (Angew. Chem. Int. Ed. 49/2012) Angewandte Chemie. 51: 12375-12375. DOI: 10.1002/Anie.201208674 |
0.661 |
|
2012 |
Cheng K, Wang X, Zhang S, Yin H. Innenrücktitelbild: Discovery of Small-Molecule Inhibitors of the TLR1/TLR2 Complex (Angew. Chem. 49/2012) Angewandte Chemie. 124: 12543-12543. DOI: 10.1002/Ange.201208674 |
0.662 |
|
2011 |
Joce C, Wiener AA, Yin H. Multi-Tox: application of the ToxR-transcriptional reporter assay to the study of multi-pass protein transmembrane domain oligomerization. Biochimica Et Biophysica Acta. 1808: 2948-53. PMID 21791200 DOI: 10.1016/J.Bbamem.2011.07.008 |
0.366 |
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2011 |
Liu L, Ghosh N, Slivka PF, Fiorini Z, Hutchinson MR, Watkins LR, Yin H. An MD2 hot-spot-mimicking peptide that suppresses TLR4-mediated inflammatory response in vitro and in vivo. Chembiochem : a European Journal of Chemical Biology. 12: 1827-31. PMID 21678541 DOI: 10.1002/Cbic.201100211 |
0.681 |
|
2011 |
Joce C, Wiener A, Yin H. Transmembrane domain oligomerization propensity determined by ToxR assay. Journal of Visualized Experiments. PMID 21654625 DOI: 10.3791/2721 |
0.418 |
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2011 |
Chavez SA, Martinko AJ, Lau C, Pham MN, Cheng K, Bevan DE, Mollnes TE, Yin H. Development of β-amino alcohol derivatives that inhibit Toll-like receptor 4 mediated inflammatory response as potential antiseptics. Journal of Medicinal Chemistry. 54: 4659-69. PMID 21591694 DOI: 10.1021/Jm2003365 |
0.531 |
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2011 |
Sammond DW, Joce C, Takeshita R, McQuate SE, Ghosh N, Martin JM, Yin H. Transmembrane peptides used to investigate the homo-oligomeric interface and binding hotspot of latent membrane protein 1. Biopolymers. 95: 772-84. PMID 21560118 DOI: 10.1002/Bip.21672 |
0.801 |
|
2011 |
Cheng K, Wang X, Yin H. Small-molecule inhibitors of the TLR3/dsRNA complex. Journal of the American Chemical Society. 133: 3764-7. PMID 21355588 DOI: 10.1021/Ja111312H |
0.596 |
|
2011 |
Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, Yin H, Rodriguez JM, Becerril J, Berndt N, Hamilton AD, Wang HG, Sebti SM. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner. The Journal of Biological Chemistry. 286: 9382-92. PMID 21148306 DOI: 10.1074/Jbc.M110.203638 |
0.761 |
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2011 |
Yin H. Abstract LB-242: Dissecting Cell Signaling Mediated by Multi-spanning Transmembrane Domain Association Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-242 |
0.411 |
|
2011 |
Liu L, Ghosh N, Slivka PF, Fiorini Z, Hutchinson MR, Watkins LR, Yin H. Inside Cover: An MD2 Hot-Spot-Mimicking Peptide that Suppresses TLR4-Mediated Inflammatory Response in vitro and in vivo (ChemBioChem 12/2011) Chembiochem. 12: 1786-1786. DOI: 10.1002/Cbic.201190054 |
0.658 |
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2010 |
Bevan DE, Martinko AJ, Loram LC, Stahl JA, Taylor FR, Joshee S, Watkins LR, Yin H. Selection, Preparation, and Evaluation of Small- Molecule Inhibitors of Toll-Like Receptor 4. Acs Medicinal Chemistry Letters. 1: 194-198. PMID 20824192 DOI: 10.1021/Ml100041F |
0.545 |
|
2010 |
Joce C, Stahl JA, Shridhar M, Hutchinson MR, Watkins LR, Fedichev PO, Yin H. Application of a novel in silico high-throughput screen to identify selective inhibitors for protein-protein interactions. Bioorganic & Medicinal Chemistry Letters. 20: 5411-3. PMID 20709548 DOI: 10.1016/J.Bmcl.2010.07.103 |
0.493 |
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2010 |
Yin H, Gao L, Shen B, Chao L, Chao J. Kallistatin inhibits vascular inflammation by antagonizing tumor necrosis factor-alpha-induced nuclear factor kappaB activation. Hypertension. 56: 260-7. PMID 20566960 DOI: 10.1161/Hypertensionaha.110.152330 |
0.302 |
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2010 |
Buchanan MM, Hutchinson M, Watkins LR, Yin H. Toll-like receptor 4 in CNS pathologies. Journal of Neurochemistry. 114: 13-27. PMID 20402965 DOI: 10.1111/J.1471-4159.2010.06736.X |
0.474 |
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2010 |
Hutchinson MR, Loram LC, Zhang Y, Shridhar M, Rezvani N, Berkelhammer D, Phipps S, Foster PS, Landgraf K, Falke JJ, Rice KC, Maier SF, Yin H, Watkins LR. Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity. Neuroscience. 168: 551-63. PMID 20381591 DOI: 10.1016/J.Neuroscience.2010.03.067 |
0.514 |
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2010 |
Hutchinson MR, Lewis SS, Coats BD, Rezvani N, Zhang Y, Wieseler JL, Somogyi AA, Yin H, Maier SF, Rice KC, Watkins LR. Possible involvement of toll-like receptor 4/myeloid differentiation factor-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences. Neuroscience. 167: 880-93. PMID 20178837 DOI: 10.1016/J.Neuroscience.2010.02.011 |
0.48 |
|
2010 |
Zhao TX, Martinko AJ, Le VH, Zhao J, Yin H. Development of agents that modulate protein-protein interactions in membranes. Current Pharmaceutical Design. 16: 1055-62. PMID 20030619 DOI: 10.2174/138161210790963878 |
0.371 |
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2010 |
Hutchinson MR, Zhang Y, Shridhar M, Evans JH, Buchanan MM, Zhao TX, Slivka PF, Coats BD, Rezvani N, Wieseler J, Hughes TS, Landgraf KE, Chan S, Fong S, Phipps S, ... ... Yin H, et al. Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain, Behavior, and Immunity. 24: 83-95. PMID 19679181 DOI: 10.1016/J.Bbi.2009.08.004 |
0.465 |
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2009 |
Tang J, Yin H, Qiu J, Tucker MJ, DeGrado WF, Gai F. Using two fluorescent probes to dissect the binding, insertion, and dimerization kinetics of a model membrane peptide. Journal of the American Chemical Society. 131: 3816-7. PMID 19256494 DOI: 10.1021/Ja809007F |
0.558 |
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2009 |
Slivka PF, Shridhar M, Lee GI, Sammond DW, Hutchinson MR, Martinko AJ, Buchanan MM, Sholar PW, Kearney JJ, Harrison JA, Watkins LR, Yin H. A peptide antagonist of the TLR4-MD2 interaction. Chembiochem : a European Journal of Chemical Biology. 10: 645-9. PMID 19184989 DOI: 10.1002/Cbic.200800769 |
0.784 |
|
2008 |
Li Y, Chase AR, Slivka PF, Baggett CT, Zhao TX, Yin H. Design, synthesis, and evaluation of biotinylated opioid derivatives as novel probes to study opioid pharmacology. Bioconjugate Chemistry. 19: 2585-9. PMID 19090701 DOI: 10.1021/Bc8003815 |
0.3 |
|
2008 |
Caputo GA, Litvinov RI, Li W, Bennett JS, Degrado WF, Yin H. Computationally designed peptide inhibitors of protein-protein interactions in membranes. Biochemistry. 47: 8600-6. PMID 18642886 DOI: 10.1021/Bi800687H |
0.727 |
|
2008 |
Slivka PF, Wong J, Caputo GA, Yin H. Peptide probes for protein transmembrane domains. Acs Chemical Biology. 3: 402-11. PMID 18533658 DOI: 10.1021/Cb800049W |
0.69 |
|
2008 |
Yin H. Exogenous agents that target transmembrane domains of proteins Angewandte Chemie - International Edition. 47: 2744-2752. PMID 18318029 DOI: 10.1002/Anie.200704780 |
0.362 |
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2007 |
White TC, Berny MA, Robinson DK, Yin H, DeGrado WF, Hanson SR, McCarty OJ. The leech product saratin is a potent inhibitor of platelet integrin alpha2beta1 and von Willebrand factor binding to collagen. The Febs Journal. 274: 1481-91. PMID 17489103 DOI: 10.1111/J.1742-4658.2007.05689.X |
0.457 |
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2007 |
Yin H, Slusky JS, Berger BW, Walters RS, Vilaire G, Litvinov RI, Lear JD, Caputo GA, Bennett JS, DeGrado WF. Computational design of peptides that target transmembrane helices. Science (New York, N.Y.). 315: 1817-22. PMID 17395823 DOI: 10.1126/Science.1136782 |
0.795 |
|
2007 |
White T, Berny M, Robinson D, Yin H, DeGrado W, Hanson S, McCarty O. THE LEECH PRODUCT SARATIN IS A POTENT INHIBITOR OF PLATELET INTEGRIN ALPHA2BETA1 AND VWF BINDING TO COLLAGEN Journal of Thrombosis and Haemostasis. 5: P-M-347-P-M-347. DOI: 10.1111/J.1538-7836.2007.Tb01268.X |
0.444 |
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2006 |
Yin H, Litvinov RI, Vilaire G, Zhu H, Li W, Caputo GA, Moore DT, Lear JD, Weisel JW, Degrado WF, Bennett JS. Activation of platelet alphaIIbbeta3 by an exogenous peptide corresponding to the transmembrane domain of alphaIIb. The Journal of Biological Chemistry. 281: 36732-41. PMID 17032655 DOI: 10.1074/Jbc.M605877200 |
0.712 |
|
2006 |
Yin H, Gerlach LO, Miller MW, Moore DT, Liu D, Vilaire G, Bennett JS, DeGrado WF. Arylamide derivatives as allosteric inhibitors of the integrin alpha2beta1/type I collagen interaction. Bioorganic & Medicinal Chemistry Letters. 16: 3380-2. PMID 16678410 DOI: 10.1016/J.Bmcl.2006.04.037 |
0.628 |
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2006 |
Yin H, Frederick KK, Liu D, Wand AJ, Degrado WF. Arylamide derivatives as peptidomimetic inhibitors of calmodulin. Organic Letters. 8: 223-5. PMID 16408880 DOI: 10.1021/Ol052478J |
0.526 |
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2006 |
White TC, Robinson DK, Yin H, DeGrado WF, Hanson SR, McCarty OJT. The Leech Product Saratin Is a Potent Inhibitor of Both VWF and Integrin α2β1 Binding to Collagen. Blood. 108: 3928-3928. DOI: 10.1182/Blood.V108.11.3928.3928 |
0.458 |
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2006 |
Yin H, Slusky JS, Berger BW, Litvinov RI, Vilaire G, Lear JD, DeGrado WF, Bennett JS. Regulation of the Function of αvβ3 in Platelets by a Designed Peptide Targeting the αv Transmembrane Domain. Blood. 108: 1504-1504. DOI: 10.1182/Blood.V108.11.1504.1504 |
0.802 |
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2005 |
Yin H, Lee GI, Sedey KA, Kutzki O, Park HS, Orner BP, Ernst JT, Wang HG, Sebti SM, Hamilton AD. Terphenyl-Based Bak BH3 alpha-helical proteomimetics as low-molecular-weight antagonists of Bcl-xL. Journal of the American Chemical Society. 127: 10191-6. PMID 16028929 DOI: 10.1021/Ja050122X |
0.782 |
|
2005 |
Chen L, Yin H, Farooqi B, Sebti S, Hamilton AD, Chen J. p53 alpha-Helix mimetics antagonize p53/MDM2 interaction and activate p53. Molecular Cancer Therapeutics. 4: 1019-25. PMID 15956260 DOI: 10.1158/1535-7163.Mct-04-0342 |
0.478 |
|
2005 |
Yin H, Hamilton AD. Strategies for targeting protein-protein interactions with synthetic agents. Angewandte Chemie (International Ed. in English). 44: 4130-63. PMID 15954154 DOI: 10.1002/Anie.200461786 |
0.499 |
|
2005 |
Yin H, Lee GI, Sedey KA, Rodriguez JM, Wang HG, Sebti SM, Hamilton AD. Terephthalamide derivatives as mimetics of helical peptides: disruption of the Bcl-x(L)/Bak interaction. Journal of the American Chemical Society. 127: 5463-8. PMID 15826183 DOI: 10.1021/Ja0446404 |
0.689 |
|
2005 |
Yin H, Lee GI, Park HS, Payne GA, Rodriguez JM, Sebti SM, Hamilton AD. Terphenyl-based helical mimetics that disrupt the p53/HDM2 interaction. Angewandte Chemie (International Ed. in English). 44: 2704-7. PMID 15765497 DOI: 10.1002/Anie.200462316 |
0.646 |
|
2005 |
Yin H, Zhu H, Vilaire G, Li W, Litvinov RI, DeGrado WF, Bennett JS. Activation of Platelet α Iibβ 3 by Exogenous Peptides Corresponding to the Transmembrane Domains of α Iib and β 3. Blood. 106: 384-384. DOI: 10.1182/Blood.V106.11.384.384 |
0.494 |
|
2005 |
Yin H, Hamilton AD. Strategien zur Modulation von Protein-Protein-Wechselwirkungen mit synthetischen Substanzen Angewandte Chemie. 117: 4200-4235. DOI: 10.1002/Ange.200461786 |
0.458 |
|
2004 |
Yin H, Hamilton AD. Terephthalamide derivatives as mimetics of the helical region of Bak peptide target Bcl-xL protein. Bioorganic & Medicinal Chemistry Letters. 14: 1375-9. PMID 15006365 DOI: 10.1016/J.Bmcl.2003.09.096 |
0.539 |
|
2003 |
Ernst JT, Becerril J, Park HS, Yin H, Hamilton AD. Design and application of an alpha-helix-mimetic scaffold based on an oligoamide-foldamer strategy: antagonism of the Bak BH3/Bcl-xL complex. Angewandte Chemie (International Ed. in English). 42: 535-9. PMID 12569483 DOI: 10.1002/Anie.200390154 |
0.762 |
|
2002 |
Kutzki O, Park HS, Ernst JT, Orner BP, Yin H, Hamilton AD. Development of a potent Bcl-x(L) antagonist based on alpha-helix mimicry. Journal of the American Chemical Society. 124: 11838-9. PMID 12358513 DOI: 10.1021/Ja026861K |
0.792 |
|
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