Kelsey Bohn, Ph.D. - Publications
Affiliations: | 2015 | Chemistry | Purdue University, West Lafayette, IN, United States |
Year | Citation | Score | |||
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2017 | Namanja-Magliano HA, Bohn K, Agrawal N, Willoughby ME, Hrycyna CA, Chmielewski J. Dual inhibitors of the human blood-brain barrier drug efflux transporters P-glycoprotein and ABCG2 based on the antiviral azidothymidine. Bioorganic & Medicinal Chemistry. PMID 28712845 DOI: 10.1016/J.Bmc.2017.07.001 | 0.782 | |||
2017 | Bohn K, Lange A, Chmielewski J, Hrycyna CA. Dual Modulation of Human P-glycoprotein and ABCG2 with Prodrug Dimers of the Atypical Antipsychotic Agent Paliperidone in a Model of the Blood-Brain Barrier. Molecular Pharmaceutics. PMID 28264565 DOI: 10.1021/Acs.Molpharmaceut.6B01044 | 0.683 | |||
2016 | Butler KV, Bohn K, Hrycyna CA, Jin J. Non-Substrate Based, Small Molecule Inhibitors of the Human Isoprenylcysteine Carboxyl Methyltransferase. Medchemcomm. 7: 1016-1021. PMID 27547295 DOI: 10.1039/C6Md00130K | 0.576 | |||
2014 | Emmert D, Campos CR, Ward D, Lu P, Namanja HA, Bohn K, Miller DS, Sharom FJ, Chmielewski J, Hrycyna CA. Reversible dimers of the atypical antipsychotic quetiapine inhibit p-glycoprotein-mediated efflux in vitro with increased binding affinity and in situ at the blood-brain barrier. Acs Chemical Neuroscience. 5: 305-17. PMID 24483607 DOI: 10.1021/Cn4002329 | 0.513 | |||
2014 | Hrycyna CA, Summers RL, Lehane AM, Pires MM, Namanja H, Bohn K, Kuriakose J, Ferdig M, Henrich PP, Fidock DA, Kirk K, Chmielewski J, Martin RE. Quinine dimers are potent inhibitors of the Plasmodium falciparum chloroquine resistance transporter and are active against quinoline-resistant P. falciparum. Acs Chemical Biology. 9: 722-30. PMID 24369685 DOI: 10.1021/Cb4008953 | 0.635 | |||
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