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Janine H. Santos - Publications

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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Rickard BP, Overchuk M, Obaid G, Ruhi MK, Demirci U, Fenton SE, Santos JH, Kessel D, Rizvi I. Photochemical Targeting of Mitochondria to Overcome Chemoresistance in Ovarian Cancer. Photochemistry and Photobiology. PMID 36117466 DOI: 10.1111/php.13723  0.428
2022 Bikomeye JC, Terwoord JM, Santos JH, Beyer AM. Emerging mitochondrial signaling mechanisms in cardio-oncology: beyond oxidative stress. American Journal of Physiology. Heart and Circulatory Physiology. PMID 35930448 DOI: 10.1152/ajpheart.00231.2022  0.487
2022 Vellers HL, Cho HY, Gladwell W, Gerrish K, Santos JH, Ofman G, Miller-DeGraff L, Mahler TB, Kleeberger SR. NRF2 Alters Mitochondrial Gene Expression in Neonate Mice Exposed to Hyperoxia. Antioxidants (Basel, Switzerland). 11. PMID 35453445 DOI: 10.3390/antiox11040760  0.417
2020 Lozoya OA, Xu F, Grenet D, Wang T, Grimm SA, Godfrey V, Waidyanatha S, Woychik RP, Santos JH. Single Nucleotide Resolution Analysis Reveals Pervasive, Long-Lasting DNA Methylation Changes by Developmental Exposure to a Mitochondrial Toxicant. Cell Reports. 32: 108131. PMID 32937126 DOI: 10.1016/j.celrep.2020.108131  0.393
2020 Bowen C, Childers G, Perry C, Martin N, McPherson CA, Lauten T, Santos J, Harry GJ. Mitochondrial-related effects of pentabromophenol, tetrabromobisphenol A, and triphenyl phosphate on murine BV-2 microglia cells. Chemosphere. 255: 126919. PMID 32402876 DOI: 10.1016/J.Chemosphere.2020.126919  0.326
2019 Ait-Aissa K, Blaszak SC, Beutner G, Tsaih SW, Morgan G, Santos JH, Flister MJ, Joyce DL, Camara AKS, Gutterman DD, Donato AJ, Porter GA, Beyer AM. Mitochondrial Oxidative Phosphorylation defect in the Heart of Subjects with Coronary Artery Disease. Scientific Reports. 9: 7623. PMID 31110224 DOI: 10.1038/S41598-019-43761-Y  0.485
2019 Lozoya OA, Wang T, Grenet D, Wolfgang TC, Sobhany M, Ganini da Silva D, Riadi G, Chandel N, Woychik RP, Santos JH. Mitochondrial acetyl-CoA reversibly regulates locus-specific histone acetylation and gene expression. Life Science Alliance. 2. PMID 30737248 DOI: 10.26508/lsa.201800228  0.434
2018 Lozoya OA, Martinez-Reyes I, Wang T, Grenet D, Bushel P, Li J, Chandel N, Woychik RP, Santos JH. Mitochondrial nicotinamide adenine dinucleotide reduced (NADH) oxidation links the tricarboxylic acid (TCA) cycle with methionine metabolism and nuclear DNA methylation. Plos Biology. 16: e2005707. PMID 29668680 DOI: 10.1371/Journal.Pbio.2005707  0.466
2018 Ganini D, Santos JH, Bonini MG, Mason RP. Switch of Mitochondrial Superoxide Dismutase into a Prooxidant Peroxidase in Manganese-Deficient Cells and Mice. Cell Chemical Biology. PMID 29398562 DOI: 10.1016/J.Chembiol.2018.01.007  0.435
2016 Halilovic A, Schmedt T, Benischke AS, Hamill CE, Chen Y, Santos JH, Jurkunas UV. Menadione-induced DNA damage leads to mitochondrial dysfunction and fragmentation during rosette formation in Fuchs Endothelial Corneal Dystrophy. Antioxidants & Redox Signaling. PMID 26935406 DOI: 10.1089/Ars.2015.6532  0.492
2015 Martínez-Reyes I, Diebold LP, Kong H, Schieber M, Huang H, Hensley CT, Mehta MM, Wang T, Santos JH, Woychik R, Dufour E, Spelbrink JN, Weinberg SE, Zhao Y, DeBerardinis RJ, et al. TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions. Molecular Cell. PMID 26725009 DOI: 10.1016/J.Molcel.2015.12.002  0.496
2015 Beyer AM, Freed JK, Durand MJ, Riedel M, Ait-Aissa K, Green P, Hockenberry JC, Morgan RG, Donato AJ, Peleg R, Gasparii M, Rokkas CK, Santos JH, Priel E, Gutterman DD. Critical Role for Telomerase in the Mechanism of Flow Mediated Dilation in the Human Microcirculation. Circulation Research. PMID 26699654 DOI: 10.1161/Circresaha.115.307918  0.427
2015 Hart PC, Mao M, de Abreu AL, Ansenberger-Fricano K, Ekoue DN, Ganini D, Kajdacsy-Balla A, Diamond AM, Minshall RD, Consolaro ME, Santos JH, Bonini MG. MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer. Nature Communications. 6: 6053. PMID 25651975 DOI: 10.1038/Ncomms7053  0.375
2014 Shaughnessy DT, McAllister K, Worth L, Haugen AC, Meyer JN, Domann FE, Van Houten B, Mostoslavsky R, Bultman SJ, Baccarelli AA, Begley TJ, Sobol RW, Hirschey MD, Ideker T, Santos JH, et al. Mitochondria, energetics, epigenetics, and cellular responses to stress. Environmental Health Perspectives. 122: 1271-8. PMID 25127496 DOI: 10.1289/Ehp.1408418  0.494
2014 Furda A, Santos JH, Meyer JN, Van Houten B. Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 1105: 419-37. PMID 24623245 DOI: 10.1007/978-1-62703-739-6_31  0.382
2014 Sharma NK, Lebedeva M, Thomas T, Kovalenko OA, Stumpf JD, Shadel GS, Santos JH. Intrinsic mitochondrial DNA repair defects in Ataxia Telangiectasia. Dna Repair. 13: 22-31. PMID 24342190 DOI: 10.1016/J.Dnarep.2013.11.002  0.385
2013 Ansenberger-Fricano K, Ganini D, Mao M, Chatterjee S, Dallas S, Mason RP, Stadler K, Santos JH, Bonini MG. The peroxidase activity of mitochondrial superoxide dismutase. Free Radical Biology & Medicine. 54: 116-24. PMID 22982047 DOI: 10.1016/J.Freeradbiomed.2012.08.573  0.436
2012 Woo DK, Green PD, Santos JH, D'Souza AD, Walther Z, Martin WD, Christian BE, Chandel NS, Shadel GS. Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC(Min/+) mice. The American Journal of Pathology. 180: 24-31. PMID 22056359 DOI: 10.1016/J.Ajpath.2011.10.003  0.537
2012 Sharma NK, Reyes A, Green P, Caron MJ, Bonini MG, Gordon DM, Holt IJ, Santos JH. Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria. Nucleic Acids Research. 40: 712-25. PMID 21937513 DOI: 10.1093/Nar/Gkr758  0.501
2010 Lee HY, Choi CS, Birkenfeld AL, Alves TC, Jornayvaz FR, Jurczak MJ, Zhang D, Woo DK, Shadel GS, Ladiges W, Rabinovitch PS, Santos JH, Petersen KF, Samuel VT, Shulman GI. Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance. Cell Metabolism. 12: 668-74. PMID 21109199 DOI: 10.1016/J.Cmet.2010.11.004  0.434
2010 Gordon DM, Santos JH. The emerging role of telomerase reverse transcriptase in mitochondrial DNA metabolism. Journal of Nucleic Acids. 2010. PMID 20936168 DOI: 10.4061/2010/390791  0.496
2010 Kovalenko OA, Caron MJ, Ulema P, Medrano C, Thomas AP, Kimura M, Bonini MG, Herbig U, Santos JH. A mutant telomerase defective in nuclear-cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunction. Aging Cell. 9: 203-19. PMID 20089117 DOI: 10.1111/J.1474-9726.2010.00551.X  0.472
2007 Lu B, Yadav S, Shah PG, Liu T, Tian B, Pukszta S, Villaluna N, Kutejová E, Newlon CS, Santos JH, Suzuki CK. Roles for the human ATP-dependent Lon protease in mitochondrial DNA maintenance. The Journal of Biological Chemistry. 282: 17363-74. PMID 17420247 DOI: 10.1074/jbc.M611540200  0.448
2006 Santos JH, Meyer JN, Mandavilli BS, Van Houten B. Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 314: 183-99. PMID 16673882 DOI: 10.1385/1-59259-973-7:183  0.379
2006 Santos JH, Meyer JN, Van Houten B. Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis. Human Molecular Genetics. 15: 1757-68. PMID 16613901 DOI: 10.1093/Hmg/Ddl098  0.474
2005 Stuart GR, Santos JH, Strand MK, Van Houten B, Copeland WC. Mitochondrial and nuclear DNA defects in Saccharomyces cerevisiae with mutations in DNA polymerase gamma associated with progressive external ophthalmoplegia. Human Molecular Genetics. 15: 363-74. PMID 16368709 DOI: 10.1093/hmg/ddi454  0.398
2004 Santos JH, Meyer JN, Skorvaga M, Annab LA, Van Houten B. Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage. Aging Cell. 3: 399-411. PMID 15569357 DOI: 10.1111/J.1474-9728.2004.00124.X  0.487
2003 Karthikeyan G, Santos JH, Graziewicz MA, Copeland WC, Isaya G, Van Houten B, Resnick MA. Reduction in frataxin causes progressive accumulation of mitochondrial damage. Human Molecular Genetics. 12: 3331-42. PMID 14570713 DOI: 10.1093/Hmg/Ddg349  0.493
2003 Santos JH, Hunakova L, Chen Y, Bortner C, Van Houten B. Cell sorting experiments link persistent mitochondrial DNA damage with loss of mitochondrial membrane potential and apoptotic cell death. The Journal of Biological Chemistry. 278: 1728-34. PMID 12424245 DOI: 10.1074/jbc.M208752200  0.397
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